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MCID: CNR001
MIFTS: 35

Coenurosis

Categories: Infectious diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Coenurosis

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MalaCards integrated aliases for Coenurosis:

Name: Coenurosis 12 15
Coenuriasis 73

Classifications:

MalaCards categories:
Global: Infectious diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:0050251
UMLS 73 C0009225
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Summaries for Coenurosis

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Disease Ontology : 12 A parasitic helminthiasis infectious disease that involves infection by metacestode larval stage (coenurus) of Taenia multiceps or Taenia serialis. Coenuri in the skin or subcutaneous tissue present as painless nodules, which manifest on the trunk, sclera, subconjuctiva, neck, shoulders, head and limbs. Coenuri in the central nervous system may cause headache, fever, vomiting, nerve palsies, jacksonian epilepsy, pachymeningitis, obstructive or communicating hydrocephalus, and intracranial arteritis with transient hemiparesis. Coenuri in the eye cause both intraocular and orbital infections.

MalaCards based summary : Coenurosis, also known as coenuriasis, is related to cysticercosis and cerebritis. An important gene associated with Coenurosis is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I), and among its related pathways/superpathways are Metabolism and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The drugs Vaccines and Dutasteride have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and brain.

Wikipedia : 76 Coenurosis, also known as caenurosis, coenuriasis, gid or sturdy, is a parasitic infection that develops... more...

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Related Diseases for Coenurosis

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Diseases related to Coenurosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 22)
# Related Disease Score Top Affiliating Genes
1 cysticercosis 29.8 MT-CO1 MT-ND1 TACSTD2
2 cerebritis 10.6
3 deafness, nonsyndromic sensorineural, mitochondrial 10.5 MT-CO1 MT-ND1
4 leber optic atrophy 10.5 MT-CO1 MT-ND1
5 cystic echinococcosis 10.4 MT-CO1 MT-ND1
6 echinococcosis 10.3 MT-CO1 MT-ND1
7 parasitic helminthiasis infectious disease 10.2 MT-CO1 MT-ND1
8 mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes 10.1 MT-CO1 MT-ND1
9 myoglobinuria 10.1 LDHA MT-CO1
10 kearns-sayre syndrome 10.0 MT-CO1 MT-ND1
11 arteritic anterior ischemic optic neuropathy 10.0 F2 MT-ND1
12 taeniasis 10.0 MT-CO1 MT-ND1 TACSTD2
13 ischemic optic neuropathy 10.0 F2 MT-ND1
14 subendocardial myocardial infarction 9.9 F2 LDHA
15 sparganosis 9.9
16 mitochondrial encephalomyopathy 9.8 MT-CO1 MT-ND1
17 phototoxic dermatitis 9.7 LDHA LDHC
18 non-gestational choriocarcinoma 9.7 LDHA LDHC
19 hermansky-pudlak syndrome 5 9.6 LDHA LDHC
20 breast abscess 9.6 LDHA LDHC
21 dressler's syndrome 9.3 LDHA LDHB LDHC
22 korean hemorrhagic fever 9.0 F2 LDHA LDHC

Graphical network of the top 20 diseases related to Coenurosis:



Diseases related to Coenurosis
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Symptoms & Phenotypes for Coenurosis

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Drugs & Therapeutics for Coenurosis

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Drugs for Coenurosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 4,Phase 3,Phase 2,Not Applicable
2
Dutasteride Approved, Investigational Phase 3 164656-23-9 152945 6918296
3
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
4 Estradiol valerate Approved, Investigational, Vet_approved Phase 3 979-32-8
5
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
6
Methyltestosterone Approved Phase 3 58-18-4 6010
7
Polyestradiol phosphate Approved Phase 3 28014-46-2
8
Testosterone Approved, Investigational Phase 3 58-22-0 6013
9
Testosterone enanthate Approved Phase 3 315-37-7 9416
10
Testosterone undecanoate Approved, Investigational Phase 3 5949-44-0
11
Dihydrotestosterone Illicit, Investigational Phase 3 521-18-6 10635
12 5-alpha Reductase Inhibitors Phase 3
13 Anabolic Agents Phase 3
14 Androgens Phase 3
15 Antineoplastic Agents, Hormonal Phase 3
16 Aromatase Inhibitors Phase 3
17 Estradiol 17 beta-cypionate Phase 3
18 Estradiol 3-benzoate Phase 3
19 Estrogen Antagonists Phase 3
20 Estrogens Phase 3
21 Hormone Antagonists Phase 3,Not Applicable
22 Hormones Phase 3,Not Applicable
23 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Not Applicable
24 Steroid Synthesis Inhibitors Phase 3
25 Testosterone 17 beta-cypionate Phase 3
26
Zinc Approved, Investigational Not Applicable 7440-66-6 23994
27 glucocorticoids Not Applicable

Interventional clinical trials:

(show all 18)
# Name Status NCT ID Phase Drugs
1 Study of Sanofi Pasteur's Intradermal Influenza Vaccine (IDflu™) in Adults and Elderly in Korea Completed NCT01215669 Phase 4
2 Testosterone and Its Metabolites in GID Completed NCT00146146 Phase 3 testosterone undecanoate alone;testosterone undecanoate plus letrozole;testosterone undecanoate plus dutasteride
3 Immunogenicity and Safety of a Vaccine Against Influenza (2010-2011 Northern Hemisphere Season, Intradermal Route) Completed NCT01138397 Phase 3
4 Lot-to-Lot Consistency Study of the Investigational, Inactivated, Split-Virion Influenza Vaccine in Adults Completed NCT00383539 Phase 3
5 Study of Inactivated, Split-Virion Influenza Vaccine Compared With the Reference Vaccine Vaxigrip® in the Elderly Completed NCT00383526 Phase 3
6 Study of the Influenza Vaccine (Split Virion, Inactivated) Northern Hemisphere 2009-2010 Formulation (Intradermal Route) Completed NCT00945438 Phase 2
7 Study of Immune Response in Adults and Elderly Subjects Vaccinated With Inactivated Influenza Vaccines Completed NCT00776438 Phase 2
8 Study of Inactivated, Split-Virion Influenza Vaccine Administered by Intradermal Route Versus Vaxigrip® in Adults Completed NCT00703651 Phase 2
9 Immunogenicity of the Inactivated Split-Virion Influenza Vaccine in Renal Transplant Subjects Completed NCT00606359 Phase 2
10 Immunogenicity of Two Dosages of Inactivated, Split-Virion Influenza Vaccine Given by an Alternate Route in the Elderly Completed NCT00296829 Phase 2
11 Immunogenicity Study of the Influenza Vaccine in Adults Completed NCT00258934 Phase 2
12 Study to Assess the Efficacy and Safety of SK-MS10 in Subjects With Acute and Chronic Gastritis Completed NCT01578811 Phase 2 Placebo;SK-MS10;SK-MS10
13 Intervention to Increase Screening for Glucocorticoid Induced Diabetes Completed NCT01743963 Not Applicable
14 Leuven Growing Into Deficit Follow-up Study Completed NCT01632813
15 Adipose-derived SVF for Treatment of Alopecia Completed NCT02626780 Not Applicable
16 Diarrhea and Bivalent Oral Polio Vaccine Immunity Completed NCT01559636 Not Applicable
17 Impact of Improving GI Symptoms on Autism Symptoms and Oxidative Stress Recruiting NCT02442115
18 Adipose-derived SVF for the Treatment of Knee OA Active, not recruiting NCT02726945 Not Applicable

Search NIH Clinical Center for Coenurosis

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Genetic Tests for Coenurosis

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Anatomical Context for Coenurosis

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MalaCards organs/tissues related to Coenurosis:

41
Eye, Skin, Brain
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Publications for Coenurosis

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Articles related to Coenurosis:

(show top 50) (show all 74)
# Title Authors Year
1
A Case of Coenurosis in a Wild Rabbit (<i>Lepus sinensis</i>) Caused by <i>Taenia serialis</i> Metacestode in Qinghai Tibetan Plateau Area, China. ( 29742875 )
2018
2
Atypical outbreak of acute coenurosis by Taenia multiceps in a sheep flock. ( 29671047 )
2018
3
The genome of tapeworm Taenia multiceps sheds light on understanding parasitic mechanism and control of coenurosis disease. ( 29947776 )
2018
4
Clinical, pathological and molecular evaluations and CT scan screening of coenurosis (Coenurus cerebralis) in sheep and calves. ( 28177040 )
2017
5
Neuropathological lesions of clinical and sub clinical Coenurosis (Coenurus cerebralis) in organized goat farms in India. ( 28426417 )
2017
6
Cerebral and non-cerebral coenurosis: on the genotypic and phenotypic diversity of Taenia multiceps. ( 27630103 )
2016
7
Diagnosis and surgical management of non-cerebral coenurosis (Taenia gaigeri) in local Black Bengal goat of Tripura: report of six cases. ( 27605809 )
2016
8
Clinical evolution of cerebral coenurosis from invasive to chronic infection in sheep and a goat. ( 27801381 )
2016
9
Application of polymerase chain reaction on cerebrospinal fluid for diagnosis of cerebral coenurosis in small ruminants. ( 26122997 )
2015
10
Regurgitations in a Lamb with Acute Coenurosis-A case Report. ( 26246831 )
2015
11
Experimental cerebral and non-cerebral coenurosis in goats: A comparative study on the morphological and molecular characteristics of the parasite. ( 26116455 )
2015
12
Clinical and morphopathological characteristics of an enzootic occurrence of acute coenurosis (Coenurus cerebralis) in a sheep herd. ( 26064018 )
2015
13
Prevalence of coenurosis in sheep and goats at three slaughter slabs in Ngorongoro District, Tanzania. ( 26306799 )
2015
14
Characteristics of non-cerebral coenurosis in tropical goats. ( 26073108 )
2015
15
Pathology in Practice. Cerebellar coenurosis in a sheep. ( 26421400 )
2015
16
Comparison of cerebral and non-cerebral coenurosis by genetic markers of glycolytic enzyme (enolase) and mitochondrial sequences in sheep and goats. ( 26527237 )
2015
17
Cerebral and non-cerebral coenurosis in small ruminants. ( 24862039 )
2014
18
Early stage of acute coenurosis in Iranian native sheep- case report. ( 25759742 )
2014
19
Cisternal cerebrospinal fluid analysis in 24 sheep with chronic coenurosis. ( 24715594 )
2014
20
Occurrence of non-cerebral coenurosis in sheep. ( 22260813 )
2013
21
Other cestodes: sparganosis, coenurosis and Taenia crassiceps cysticercosis. ( 23829923 )
2013
22
MRS findings in cerebral coenurosis due to Taenia multiceps. ( 21699611 )
2013
23
Molecular identification of Taenia serialis coenurosis in a wild Ethiopian gelada (Theropithecus gelada). ( 24050944 )
2013
24
Morphological and molecular characterization of bovine coenurosis in Sardinia, Italy. ( 23274489 )
2013
25
Magnetic resonance imaging of the brain and skull of sheep with cerebral coenurosis. ( 23176417 )
2012
26
Molecular characterization of subcutaneous and muscular coenurosis of goats in United Arab Emirates. ( 22884911 )
2012
27
Acute coenurosis of dairy sheep from 11 flocks in Greece. ( 22506508 )
2012
28
Diagnosis and treatment of coenurosis in sheep. ( 22503036 )
2012
29
AIRP best cases in radiologic-pathologic correlation: human coenurosis (Taenia Larva). ( 22411946 )
2012
30
Cerebral coenurosis in a cat caused by Taenia serialis: neurological, magnetic resonance imaging and pathological features. ( 22918847 )
2012
31
Prevalence and molecular characterization of bovine coenurosis from Eastern Anatolian region of Turkey. ( 21074326 )
2011
32
Survey on coenurosis in sheep and goats in Egypt. ( 21947971 )
2011
33
Cerebral coenurosis mimicking hydatid disease - report of two cases from South India. ( 21176715 )
2011
34
First report of coenurosis in sheep in the State of Mato Grosso do Sul, Brazil. ( 21184708 )
2010
35
Non-cerebral coenurosis in goats. ( 20502917 )
2010
36
Preliminary field trial of a vaccine against coenurosis caused by Taenia multiceps. ( 19345506 )
2009
37
Cerebellar dysfunction in a calf with chronic coenurosis. ( 19377093 )
2009
38
Coenurosis in a beef cattle herd in Greece. ( 18024927 )
2007
39
Two rare clinical manifestations of coenurosis in sheep. ( 17027156 )
2007
40
A survey of Taenia multiceps coenurosis in Sardinian sheep. ( 16973285 )
2007
41
Updates on morphobiology, epidemiology and molecular characterization of coenurosis in sheep. ( 16881398 )
2006
42
Spinal coenurosis causing posterior paralysis in a goat in Mongolia. ( 16489162 )
2006
43
Coenurosis in a pet rabbit. ( 11258733 )
2001
44
Surgical treatment of coenurosis (gid) in sheep. ( 11014487 )
2000
45
Correlation between MRI, computed tomographic findings and clinical signs in a case of ovine coenurosis. ( 10777046 )
2000
46
Outbreak of coenurosis (Taenia species) in anglonubian goats in the Sultanate of Oman. ( 10204227 )
1999
47
Computed tomographic findings in ovine coenurosis. ( 10528835 )
1999
48
Human coenurosis in North America: case reports and review. ( 9770151 )
1998
49
Fatal cerebral coenurosis in a cat. ( 7928552 )
1994
50
Long-term follow-up of the surgical treatment of intracranial coenurosis. ( 2334526 )
1990
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Variations for Coenurosis

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Expression for Coenurosis

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Search GEO for disease gene expression data for Coenurosis.
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Pathways for Coenurosis

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Pathways related to Coenurosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Metabolism 66
Show member pathways
 13.61 GOT2 LDHA LDHB LDHC MT-CO1 MT-ND1
2
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. 66
Show member pathways
 13.11 LDHA LDHB LDHC MT-CO1 MT-ND1
3
Glucose metabolism 66
Show member pathways
 12.25 GOT2 LDHA LDHB LDHC
4
Pyruvate metabolism and Citric Acid (TCA) cycle 66
Show member pathways
 11.7 LDHA LDHB LDHC
5
Glucagon signaling pathway 37
11.51 LDHA LDHB LDHC
6
Amino Acid metabolism 1
11.44 GOT2 LDHA
7
Sulfur amino acid metabolism 66
Show member pathways
 11.34 GOT2 LDHA LDHB LDHC
8
Pyruvate metabolism 37
Show member pathways
 11.06 LDHA LDHB LDHC
9
Propanoate metabolism 37
10.84 LDHA LDHB LDHC
10
Metabolic States and Circadian Oscillators 64
Show member pathways
 9.88 LDHA LDHB LDHC
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GO Terms for Coenurosis

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Cellular components related to Coenurosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.1 F2 GOT2 LDHA LDHB LDHC TACSTD2
2 respiratory chain GO:0070469 8.96 MT-CO1 MT-ND1

Biological processes related to Coenurosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.65 LDHA LDHB LDHC MT-CO1 MT-ND1
2 carbohydrate metabolic process GO:0005975 9.54 LDHA LDHB LDHC
3 NAD metabolic process GO:0019674 9.32 LDHA LDHB
4 lactate metabolic process GO:0006089 9.16 LDHA LDHB
5 pyruvate metabolic process GO:0006090 9.13 LDHA LDHB LDHC
6 carboxylic acid metabolic process GO:0019752 8.8 LDHA LDHB LDHC

Molecular functions related to Coenurosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.65 LDHA LDHB LDHC MT-CO1 MT-ND1
2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.33 LDHA LDHB LDHC
3 NAD binding GO:0051287 9.32 LDHA LDHB
4 lactate dehydrogenase activity GO:0004457 8.96 LDHA LDHB
5 L-lactate dehydrogenase activity GO:0004459 8.8 LDHA LDHB LDHC
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Sources for Coenurosis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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