CGF1
MCID: CGN007
MIFTS: 35

Cognitive Function 1, Social (CGF1)

Aliases & Classifications for Cognitive Function 1, Social

MalaCards integrated aliases for Cognitive Function 1, Social:

Name: Cognitive Function 1, Social 57 73
Cognitive Function-1, Social 13
Social Cognition 57
Cgf1 57

Characteristics:

OMIM:

57
Inheritance:
x-linked imprinting


External Ids:

OMIM 57 300082
MedGen 42 C1848140
SNOMED-CT via HPO 69 88425004
UMLS 73 C1848140

Summaries for Cognitive Function 1, Social

MalaCards based summary : Cognitive Function 1, Social, also known as cognitive function-1, social, is related to perrault syndrome 1 and schizophrenia. An important gene associated with Cognitive Function 1, Social is CGF1 (Cognitive Function 1, Social). The drugs Insulin, Globin Zinc and Complement Factor I have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and prefrontal cortex, and related phenotype is abnormality of the nervous system.

Description from OMIM: 300082

Related Diseases for Cognitive Function 1, Social

Diseases related to Cognitive Function 1, Social via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
# Related Disease Score Top Affiliating Genes
1 perrault syndrome 1 11.1
2 schizophrenia 10.6
3 autism 10.3
4 frontotemporal dementia 10.3
5 dementia 10.3
6 frontotemporal dementia with parkinsonism-17 10.3
7 personality disorder 10.2
8 autism spectrum disorder 10.2
9 multiple sclerosis 10.2
10 bipolar disorder 10.2
11 borderline personality disorder 10.2
12 brain injury 10.2
13 anorexia nervosa 10.1
14 traumatic brain injury 10.1
15 digeorge syndrome 10.1
16 anxiety 10.1
17 relapsing-remitting multiple sclerosis 10.1
18 alzheimer disease 10.1
19 williams-beuren syndrome 10.1
20 depression 10.1
21 huntington disease 10.0
22 dysphasia, familial developmental 10.0
23 asperger syndrome 10.0
24 specific language impairment 10.0
25 epilepsy 10.0
26 psychotic disorder 10.0
27 eating disorder 10.0
28 47, xxy 10.0
29 alcohol dependence 9.9
30 attention deficit-hyperactivity disorder 9.9
31 fragile x syndrome 9.9
32 alcohol abuse 9.9
33 alexithymia 9.9
34 autosomal dominant cerebellar ataxia 9.9
35 schizoaffective disorder 9.9
36 behavioral variant of frontotemporal dementia 9.9
37 gilles de la tourette syndrome 9.8
38 obsessive-compulsive disorder 9.8
39 parkinson disease, late-onset 9.8
40 major depressive disorder 9.8
41 spinal cord injury 9.8
42 temporal lobe epilepsy 9.8
43 fetal alcohol syndrome 9.8
44 schizotypal personality disorder 9.8
45 amnestic disorder 9.8
46 disease of mental health 9.8
47 mental depression 9.8
48 cannabis dependence 9.8
49 post-traumatic stress disorder 9.8
50 mood disorder 9.8

Graphical network of the top 20 diseases related to Cognitive Function 1, Social:



Diseases related to Cognitive Function 1, Social

Symptoms & Phenotypes for Cognitive Function 1, Social

Symptoms via clinical synopsis from OMIM:

57
Neuro:
social adjustment
verbal and higher-order executive function skills
development of sexual dimorphism in social behavior


Clinical features from OMIM:

300082

Human phenotypes related to Cognitive Function 1, Social:

32
# Description HPO Frequency HPO Source Accession
1 abnormality of the nervous system 32 HP:0000707

Drugs & Therapeutics for Cognitive Function 1, Social

Drugs for Cognitive Function 1, Social (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Insulin, Globin Zinc
2 Complement Factor I
3 Mitogens
4 insulin

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects Completed NCT02304731 Phase 4
2 Investigating Gains in Neurocognition in an Intervention Trial of Exercise Recruiting NCT02875301 Phase 3
3 The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health Recruiting NCT02917928 Phase 2 Placebo
4 Social Cognition Assessment in Young Adults Completed NCT02922400 Not Applicable
5 Effects of Wheat Bran Extract on Cognitive and Memory Function Completed NCT02489747 Not Applicable
6 Effects of Physical and Cognitive Training in Neuroplasticity, Health and Cognition. Movement Project Completed NCT03123900 Not Applicable
7 Social Cognition and Interaction Training for Adults With Psychotic Disorders: An Open Pilot Study in Finland Completed NCT02399020 Not Applicable
8 Associations of Cognition, Fitness, and Body Composition Among Ethnic Minority Youth Completed NCT03342924 Not Applicable
9 Comprehensive Versus Traditional Lifestyle Program Completed NCT03182621 Not Applicable
10 Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children Completed NCT02295072 Not Applicable
11 System-IGF-1 Pathway and Alzheimer's Disease Completed NCT00647478
12 Heart Rate Variability and Cognitive Load on Image-Based Virtual Reality Instructional Design in Otolaryngology Recruiting NCT03501641 Not Applicable
13 Physical Exercise for Education ('Fit to Study') Active, not recruiting NCT03286725 Not Applicable

Search NIH Clinical Center for Cognitive Function 1, Social

Genetic Tests for Cognitive Function 1, Social

Anatomical Context for Cognitive Function 1, Social

MalaCards organs/tissues related to Cognitive Function 1, Social:

41
Brain, Cortex, Prefrontal Cortex, Heart, Testes, Temporal Lobe, Spinal Cord

Publications for Cognitive Function 1, Social

Articles related to Cognitive Function 1, Social:

(show top 50) (show all 276)
# Title Authors Year
1
From "under" to "over" social cognition in schizophrenia: Is there distinct profiles of impairments according to negative and positive symptoms? ( 30534527 )
2019
2
Resting state connectivity mediates the relationship between collectivism and social cognition. ( 29208492 )
2018
3
Normal Performance in Non-Visual Social Cognition Tasks in Women with Turner Syndrome. ( 29780353 )
2018
4
Subjective and Objective: Alexithymia and Social Cognition in Eating Disorders. ( 29916406 )
2018
5
Differences in frontotemporal dysfunction during social and non-social cognition tasks between patients with autism spectrum disorder and schizophrenia. ( 29445197 )
2018
6
Salivary testosterone in relation to social cognition and social anxiety in children and adolescents with 47,XXY (Klinefelter syndrome). ( 30036387 )
2018
7
Association Between Psychosis in Elderly Patients With Alzheimer Disease and Impaired Social Cognition. ( 29800937 )
2018
8
The Relationship Between Social Cognition and Awareness in Alzheimer Disease. ( 29187026 )
2018
9
Autism, early psychosis, and social anxiety disorder: understanding the role of social cognition and its relationship to disability in young adults with disorders characterized by social impairments. ( 30367029 )
2018
10
The Relationship of Clinical Symptoms with Social Cognition in Children Diagnosed with Attention Deficit Hyperactivity Disorder, Specific Learning Disorder or Autism Spectrum Disorder. ( 30518170 )
2018
11
Social Cognition in Schizophrenia and Autism Spectrum Disorders: A Systematic Review and Meta-Analysis of Direct Comparisons. ( 30459645 )
2018
12
Local structural connectivity is associated with social cognition in autism spectrum disorder. ( 30423029 )
2018
13
Transcranial direct current stimulation (tDCS) over right temporoparietal junction (rTPJ) for social cognition and social skills in adults with autism spectrum disorder (ASD). ( 30341695 )
2018
14
Prior Knowledge, Episodic Control and Theory of Mind in Autism: Toward an Integrative Account of Social Cognition. ( 30233436 )
2018
15
Social behaviour and social cognition in high-functioning adolescents with autism spectrum disorder (ASD): two sides of the same coin? ( 29959562 )
2018
16
Social cognition moderates the relationship between neurocognition and community functioning in bipolar disorder. ( 29631204 )
2018
17
What Is Going On? The Process of Generating Questions about Emotion and Social Cognition in Bipolar Disorder and Schizophrenia with Cartoon Situations and Faces. ( 29673215 )
2018
18
Functional outcome and social cognition in bipolar disorder: Is there a connection? ( 29787961 )
2018
19
Social Cognition and Borderline Personality Disorder: Splitting and Trust Impairment Findings. ( 30447728 )
2018
20
Pattern of social cognition deficits in individuals with borderline personality disorder. ( 29554632 )
2018
21
The effects of oxytocin on social cognition in borderline personality disorder. ( 29273344 )
2018
22
Rehabilitation of social cognition impairment after traumatic brain injury: A systematic review. ( 30553571 )
2018
23
Participation after Traumatic Brain Injury: the surplus value of social cognition tests beyond measures for executive functioning and dysexecutive behavior in a statistical prediction model. ( 30325200 )
2018
24
Relationship between social cognition and social behaviour following traumatic brain injury. ( 30325217 )
2018
25
Social cognition and traumatic brain injury: current knowledge. ( 30325238 )
2018
26
Treatment of social cognition impairments in patients with traumatic brain injury : a critical review. ( 30346856 )
2018
27
Social cognition and interaction training for major depression: A preliminary study. ( 30551340 )
2018
28
Social Cognition Differentiates Behavioral Variant Frontotemporal Dementia From Other Neurodegenerative Diseases and Psychiatric Disorders. ( 29501411 )
2018
29
The relationship between social cognition and executive function in Major Depressive Disorder in high-functioning adolescents and young adults. ( 29550719 )
2018
30
Social cognition in myotonic dystrophy type 1: Specific or secondary impairment? ( 30248121 )
2018
31
Role of social cognition in post-traumatic stress disorder: A review and meta-analysis. ( 30221467 )
2018
32
Neurocognitive and Metacognitive Profiles of Intact Social Cognition in Prolonged Schizophrenia. ( 30439777 )
2018
33
Neurobiology and treatment of social cognition in schizophrenia: Bridging the bed-bench gap. ( 30391541 )
2018
34
Social cognition in schizophrenia: The role of mentalizing in moral dilemma decision-making. ( 30415199 )
2018
35
Dissociated features of social cognition altered in mouse models of schizophrenia: Focus on social dominance and acoustic communication. ( 30236964 )
2018
36
Social cognition and short-term prediction of suicidal ideation in schizophrenia. ( 30243127 )
2018
37
The effects of combined oxytocin and cognitive behavioral social skills training on social cognition in schizophrenia. ( 30180918 )
2018
38
Add-on Yoga Therapy for Social Cognition in Schizophrenia: A Pilot Study. ( 30233119 )
2018
39
Social Cognition and Neurocognition in Schizophrenia and Healthy Controls: Intercorrelations of Performance and Effects of Manipulations Aimed at Increasing Task Difficulty. ( 30131729 )
2018
40
Loss of white matter connections after severe traumatic brain injury (TBI) and its relationship to social cognition. ( 29948905 )
2018
41
Aspects of alcohol use disorder affecting social cognition as assessed using the Mini Social and Emotional Assessment (mini-SEA). ( 29674250 )
2018
42
Sensory over-responsivity and social cognition in ASD: Effects of aversive sensory stimuli and attentional modulation on neural responses to social cues. ( 28284787 )
2018
43
Genetic and clinical features of social cognition in 22q11.2 deletion syndrome. ( 30004142 )
2018
44
Social cognition and self-other distinctions in neuropsychiatry: Insights from schizophrenia and Tourette syndrome. ( 29195921 )
2018
45
Brain-Derived Neurotrophic Factor (BDNF) and Serotonin Transporter (SERT) in Platelets of Patients with Mild Huntington's Disease: Relationships with Social Cognition Symptoms. ( 30039833 )
2018
46
Social Cognition and Oxytocin in Huntington's Disease: New Insights. ( 30149684 )
2018
47
Performance of Patients with Early Parkinson Disease on an Executive and Social Cognition Battery. ( 30239464 )
2018
48
Neuropsychological profile and social cognition in congenital central hypoventilation syndrome (CCHS): Correlation with neuroimaging in a clinical case. ( 28708033 )
2018
49
Intranasal oxytocin, social cognition and neurodevelopmental disorders: A meta-analysis. ( 29032324 )
2018
50
Schizotypal personality traits and social cognition are associated with childhood trauma exposure. ( 29923348 )
2018

Variations for Cognitive Function 1, Social

Expression for Cognitive Function 1, Social

Search GEO for disease gene expression data for Cognitive Function 1, Social.

Pathways for Cognitive Function 1, Social

GO Terms for Cognitive Function 1, Social

Sources for Cognitive Function 1, Social

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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