CGF1
MCID: CGN007
MIFTS: 31

Cognitive Function 1, Social (CGF1)

Aliases & Classifications for Cognitive Function 1, Social

MalaCards integrated aliases for Cognitive Function 1, Social:

Name: Cognitive Function 1, Social 58 74
Cognitive Function-1, Social 13
Social Cognition 58
Cgf1 58

Characteristics:

OMIM:

58
Inheritance:
x-linked imprinting


External Ids:

OMIM 58 300082
MedGen 43 C1848140
SNOMED-CT via HPO 70 88425004
UMLS 74 C1848140

Summaries for Cognitive Function 1, Social

MalaCards based summary : Cognitive Function 1, Social, also known as cognitive function-1, social, is related to cone-rod dystrophy and hearing loss 2 and schizophrenia. An important gene associated with Cognitive Function 1, Social is CGF1 (Cognitive Function 1, Social). The drugs Insulin, Globin Zinc and Complement Factor I have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and cortex, and related phenotype is abnormality of the nervous system.

Description from OMIM: 300082

Related Diseases for Cognitive Function 1, Social

Diseases related to Cognitive Function 1, Social via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 137)
# Related Disease Score Top Affiliating Genes
1 cone-rod dystrophy and hearing loss 2 11.1
2 schizophrenia 10.7
3 autism 10.5
4 frontotemporal dementia 10.4
5 dementia 10.4
6 bipolar disorder 10.3
7 autism spectrum disorder 10.3
8 personality disorder 10.3
9 multiple sclerosis 10.3
10 borderline personality disorder 10.3
11 brain injury 10.2
12 anorexia nervosa 10.2
13 traumatic brain injury 10.2
14 relapsing-remitting multiple sclerosis 10.2
15 depression 10.2
16 digeorge syndrome 10.1
17 epilepsy 10.1
18 anxiety 10.1
19 alzheimer disease 10.1
20 attention deficit-hyperactivity disorder 10.1
21 williams-beuren syndrome 10.1
22 pol iii-related leukodystrophies 10.1
23 huntington disease 10.0
24 major depressive disorder 10.0
25 temporal lobe epilepsy 10.0
26 mental depression 10.0
27 eating disorder 10.0
28 alcohol dependence 10.0
29 fragile x syndrome 10.0
30 dysphasia, familial developmental 10.0
31 stroke, ischemic 10.0
32 spinal cord injury 10.0
33 asperger syndrome 10.0
34 specific language impairment 10.0
35 47, xxy 10.0
36 amyotrophic lateral sclerosis 1 9.9
37 blood group, colton system 9.9
38 parkinson disease, late-onset 9.9
39 alcohol abuse 9.9
40 intermittent claudication 9.9
41 alexithymia 9.9
42 autosomal dominant cerebellar ataxia 9.9
43 lateral sclerosis 9.9
44 schizoaffective disorder 9.9
45 behavioral variant of frontotemporal dementia 9.9
46 gilles de la tourette syndrome 9.8
47 noonan syndrome 1 9.8
48 obsessive-compulsive disorder 9.8
49 down syndrome 9.8
50 aging 9.8

Graphical network of the top 20 diseases related to Cognitive Function 1, Social:



Diseases related to Cognitive Function 1, Social

Symptoms & Phenotypes for Cognitive Function 1, Social

Human phenotypes related to Cognitive Function 1, Social:

33
# Description HPO Frequency HPO Source Accession
1 abnormality of the nervous system 33 HP:0000707

Symptoms via clinical synopsis from OMIM:

58
Neuro:
social adjustment
verbal and higher-order executive function skills
development of sexual dimorphism in social behavior

Clinical features from OMIM:

300082

Drugs & Therapeutics for Cognitive Function 1, Social

Drugs for Cognitive Function 1, Social (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Insulin, Globin Zinc
2 Complement Factor I
3 Mitogens
4 insulin

Interventional clinical trials:

(show all 15)
# Name Status NCT ID Phase Drugs
1 Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects Completed NCT02304731 Phase 4
2 Investigating Gains in Neurocognition in an Intervention Trial of Exercise Recruiting NCT02875301 Phase 3
3 The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health Recruiting NCT02917928 Phase 2 Placebo
4 Social Cognition Assessment in Young Adults Completed NCT02922400 Not Applicable
5 Effects of Wheat Bran Extract on Cognitive and Memory Function Completed NCT02489747 Not Applicable
6 Effects of Physical and Cognitive Training in Neuroplasticity, Health and Cognition. Movement Project Completed NCT03123900 Not Applicable
7 Social Cognition and Interaction Training for Adults With Psychotic Disorders: An Open Pilot Study in Finland Completed NCT02399020 Not Applicable
8 Associations of Cognition, Fitness, and Body Composition Among Ethnic Minority Youth Completed NCT03342924 Not Applicable
9 Comprehensive Versus Traditional Lifestyle Program Completed NCT03182621 Not Applicable
10 Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children Completed NCT02295072 Not Applicable
11 System-IGF-1 Pathway and Alzheimer's Disease Completed NCT00647478
12 Heart Rate Variability and Cognitive Load on Image-Based Virtual Reality Instructional Design in Otolaryngology Recruiting NCT03501641 Not Applicable
13 The Cogni-Action Project: Physical Activity, Brain, and Cognition Active, not recruiting NCT03894241 Not Applicable
14 Physical Exercise for Education ('Fit to Study') Active, not recruiting NCT03286725 Not Applicable
15 Comparison of the Effectiveness of Different Home Exercise Programs Not yet recruiting NCT03878394 Not Applicable

Search NIH Clinical Center for Cognitive Function 1, Social

Genetic Tests for Cognitive Function 1, Social

Anatomical Context for Cognitive Function 1, Social

MalaCards organs/tissues related to Cognitive Function 1, Social:

42
Brain, Heart, Cortex, Temporal Lobe, Bone, Testes, Prefrontal Cortex

Publications for Cognitive Function 1, Social

Articles related to Cognitive Function 1, Social:

(show top 50) (show all 358)
# Title Authors Year
1
Social Cognition and the Aging Brain. ( 30986825 )
2019
2
More than words: Social cognition across variants of primary progressive aphasia. ( 30876954 )
2019
3
Altered social cognition and connectivity of default mode networks in the co-occurrence of autistic spectrum disorder and attention deficit hyperactivity disorder. ( 30843728 )
2019
4
Social Cognition in Autism and Other Neurodevelopmental Disorders: A Co-twin Control Study. ( 30972652 )
2019
5
Can vagus nerve stimulation improve social cognition in autism? ( 29615199 )
2019
6
Possible association between social cognition and metabolic dysfunctions in Bipolar Disorder and Schizophrenia: Preliminary results. ( 30795487 )
2019
7
Social cognition and interaction training (SCIT) for partially remitted patients with bipolar disorder in China. ( 30852431 )
2019
8
Social Cognition, Language, and Social Behavior in 7-Year-Old Children at Familial High-Risk of Developing Schizophrenia or Bipolar Disorder: The Danish High Risk and Resilience Study VIA 7-A Population-Based Cohort Study. ( 30852621 )
2019
9
Social cognition in first episode bipolar disorder patients. ( 30616122 )
2019
10
Social cognition in bipolar disorder: the role of sociodemographic, clinical and neurocognitive variables in emotional intelligence. ( 30786002 )
2019
11
Brain structural correlates of executive and social cognition profiles in behavioral variant frontotemporal dementia and elderly bipolar disorder. ( 28219620 )
2019
12
Intranasal oxytocin modulates higher order social cognition in body dysmorphic disorder. ( 30614171 )
2019
13
Effects of Childhood Maltreatment on Social Cognition and Brain Functional Connectivity in Borderline Personality Disorder Patients. ( 30988667 )
2019
14
Social cognition and emotion regulation: a multifaceted treatment (T-ScEmo) for patients with traumatic brain injury. ( 30798631 )
2019
15
Rehabilitative Support for Persons with Dementia and Their Families to Acquire Self-Management Attitude and Improve Social Cognition and Sense of Cognitive Empathy. ( 31023994 )
2019
16
Patterns of impaired social cognition in children and adolescents with epilepsy: The borders between different epilepsy phenotypes. ( 30894295 )
2019
17
Cognitive functions and social cognition in multiple sclerosis: An overview. ( 30877728 )
2019
18
Social cognition deficits and the role of amygdala in relapsing remitting multiple sclerosis patients without cognitive impairment. ( 30710839 )
2019
19
Role of social cognition in post-traumatic stress disorder: A review and meta-analysis. ( 30221467 )
2019
20
Nonsocial and social cognition in schizophrenia: current evidence and future directions. ( 31059632 )
2019
21
The Effect of Intranasal Oxytocin on Measures of Social Cognition in Schizophrenia: A Negative Report. ( 31037274 )
2019
22
Social cognition in schizophrenia: Validation of an ecological fMRI task. ( 30904774 )
2019
23
Social cognition in early course of schizophrenia: Exploratory factor analysis. ( 30832194 )
2019
24
Endogenous oxytocin levels are associated with impaired social cognition and neurocognition in schizophrenia. ( 30849617 )
2019
25
Cognition, social cognition, and Self-assessment in schizophrenia: prediction of different elements of everyday functional outcomes. ( 30683165 )
2019
26
From "under" to "over" social cognition in schizophrenia: Is there distinct profiles of impairments according to negative and positive symptoms? ( 30534527 )
2019
27
Oscillatory neural networks underlying resting-state, attentional control and social cognition task conditions in children with ASD, ADHD and ASD+ADHD. ( 30954695 )
2019
28
Co-designing a virtual world with young people to deliver social cognition therapy in early psychosis. ( 30908854 )
2019
29
Social cognition impairments are associated with behavioural changes in the long term after stroke. ( 30875394 )
2019
30
Short running head: Social Cognition Impairments after Stroke. ( 30831095 )
2019
31
Salivary testosterone in relation to social cognition and social anxiety in children and adolescents with 47,XXY (Klinefelter syndrome). ( 30036387 )
2018
32
Subjective and Objective: Alexithymia and Social Cognition in Eating Disorders. ( 29916406 )
2018
33
Association Between Psychosis in Elderly Patients With Alzheimer Disease and Impaired Social Cognition. ( 29800937 )
2018
34
The Relationship Between Social Cognition and Awareness in Alzheimer Disease. ( 29187026 )
2018
35
Autism, early psychosis, and social anxiety disorder: understanding the role of social cognition and its relationship to disability in young adults with disorders characterized by social impairments. ( 30367029 )
2018
36
The Relationship of Clinical Symptoms with Social Cognition in Children Diagnosed with Attention Deficit Hyperactivity Disorder, Specific Learning Disorder or Autism Spectrum Disorder. ( 30518170 )
2018
37
Local structural connectivity is associated with social cognition in autism spectrum disorder. ( 30423029 )
2018
38
Social Cognition in Schizophrenia and Autism Spectrum Disorders: A Systematic Review and Meta-Analysis of Direct Comparisons. ( 30459645 )
2018
39
Transcranial direct current stimulation (tDCS) over right temporoparietal junction (rTPJ) for social cognition and social skills in adults with autism spectrum disorder (ASD). ( 30341695 )
2018
40
Prior Knowledge, Episodic Control and Theory of Mind in Autism: Toward an Integrative Account of Social Cognition. ( 30233436 )
2018
41
Social behaviour and social cognition in high-functioning adolescents with autism spectrum disorder (ASD): two sides of the same coin? ( 29959562 )
2018
42
Corrigendum to "Phenotype continuum between autism and schizophrenia: Evidence from the Movie for the Assessment of the social cognition (MASC)" [Schizophr. Res. 185 (2017) 161-166]. ( 29550055 )
2018
43
Neural mechanisms of behavioral change in young adults with high-functioning autism receiving virtual reality social cognition training: A pilot study. ( 29517857 )
2018
44
Differences in frontotemporal dysfunction during social and non-social cognition tasks between patients with autism spectrum disorder and schizophrenia. ( 29445197 )
2018
45
Impaired White Matter Integrity and Social Cognition in High-Function Autism: Diffusion Tensor Imaging Study. ( 29486546 )
2018
46
Assessing Personal Constructs of Adolescents with Autism Spectrum Disorder: A Person-Centered Measure of Social Cognition. ( 29071565 )
2018
47
Functional outcome and social cognition in bipolar disorder: Is there a connection? ( 29787961 )
2018
48
Social cognition moderates the relationship between neurocognition and community functioning in bipolar disorder. ( 29631204 )
2018
49
What Is Going On? The Process of Generating Questions about Emotion and Social Cognition in Bipolar Disorder and Schizophrenia with Cartoon Situations and Faces. ( 29673215 )
2018
50
Social Cognition and Borderline Personality Disorder: Splitting and Trust Impairment Findings. ( 30447728 )
2018

Variations for Cognitive Function 1, Social

Expression for Cognitive Function 1, Social

Search GEO for disease gene expression data for Cognitive Function 1, Social.

Pathways for Cognitive Function 1, Social

GO Terms for Cognitive Function 1, Social

Sources for Cognitive Function 1, Social

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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