Aliases & Classifications for Cognitive Function 1, Social

MalaCards integrated aliases for Cognitive Function 1, Social:

Name: Cognitive Function 1, Social 57 73
Cognitive Function-1, Social 13
Social Cognition 57
Cgf1 57

Characteristics:

OMIM:

57
Inheritance:
x-linked imprinting


External Ids:

OMIM 57 300082
MedGen 42 C1848140
SNOMED-CT via HPO 69 88425004
UMLS 73 C1848140

Summaries for Cognitive Function 1, Social

MalaCards based summary : Cognitive Function 1, Social, also known as cognitive function-1, social, is related to schizophrenia and frontotemporal dementia. An important gene associated with Cognitive Function 1, Social is CGF1 (Cognitive Function 1, Social). The drugs Complement Factor I and insulin have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and cortex, and related phenotype is abnormality of the nervous system.

Description from OMIM: 300082

Related Diseases for Cognitive Function 1, Social

Diseases related to Cognitive Function 1, Social via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Related Disease Score Top Affiliating Genes
1 schizophrenia 10.4
2 frontotemporal dementia 10.2
3 dementia 10.2
4 frontotemporal dementia with parkinsonism-17 10.2
5 autism 10.1
6 multiple sclerosis 10.0
7 bipolar disorder 10.0
8 autism spectrum disorder 10.0
9 anorexia nervosa 10.0
10 williams-beuren syndrome 9.9
11 personality disorder 9.9
12 aging 9.9
13 anxiety 9.9
14 asperger syndrome 9.9
15 borderline personality disorder 9.9
16 relapsing-remitting multiple sclerosis 9.9
17 alzheimer disease 9.8
18 brain injury 9.8
19 alexithymia 9.8
20 behavioral variant of frontotemporal dementia 9.8
21 fragile x syndrome 9.7
22 dysphasia, familial developmental 9.7
23 spinal cord injury 9.7
24 traumatic brain injury 9.7
25 specific language impairment 9.7
26 autosomal dominant cerebellar ataxia 9.7
27 epilepsy 9.7
28 cannabis dependence 9.7
29 turner syndrome 9.7
30 depression 9.7
31 apnea, obstructive sleep 9.6
32 breast cancer 9.6
33 colorectal cancer 9.6
34 noonan syndrome 1 9.6
35 parkinson disease, late-onset 9.6
36 spinocerebellar ataxia 2 9.6
37 phenylketonuria 9.6
38 supranuclear palsy, progressive, 1 9.6
39 bulimia nervosa 9.6
40 hereditary spastic paraplegia 9.6
41 temporal lobe epilepsy 9.6
42 fetal alcohol syndrome 9.6
43 sleep apnea 9.6
44 pervasive developmental disorder 9.6
45 aphasia 9.6
46 anosognosia 9.6
47 antisocial personality disorder 9.6
48 hemiplegia 9.6
49 social phobia 9.6
50 intermittent explosive disorder 9.6

Graphical network of the top 20 diseases related to Cognitive Function 1, Social:



Diseases related to Cognitive Function 1, Social

Symptoms & Phenotypes for Cognitive Function 1, Social

Symptoms via clinical synopsis from OMIM:

57
Neuro:
social adjustment
verbal and higher-order executive function skills
development of sexual dimorphism in social behavior


Clinical features from OMIM:

300082

Human phenotypes related to Cognitive Function 1, Social:

32
# Description HPO Frequency HPO Source Accession
1 abnormality of the nervous system 32 HP:0000707

Drugs & Therapeutics for Cognitive Function 1, Social

Drugs for Cognitive Function 1, Social (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement Factor I
2 insulin
3 Insulin, Globin Zinc
4 Mitogens

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 Physical Exercise and Pollution: Cardiorrespiratory, Cerebral and Molecular Aspects Completed NCT02304731 Phase 4
2 Investigating Gains in Neurocognition in an Intervention Trial of Exercise Recruiting NCT02875301 Phase 3
3 The Potential of Carnosine Supplementation in Optimising Cardiometabolic Health Recruiting NCT02917928 Phase 2 Placebo
4 Social Cognition Assessment in Young Adults Completed NCT02922400 Not Applicable
5 Effects of Wheat Bran Extract on Cognitive and Memory Function Completed NCT02489747 Not Applicable
6 Social Cognition and Interaction Training for Adults With Psychotic Disorders: An Open Pilot Study in Finland Completed NCT02399020 Not Applicable
7 Associations of Cognition, Fitness, and Body Composition Among Ethnic Minority Youth Completed NCT03342924 Not Applicable
8 Comprehensive Versus Traditional Lifestyle Program Completed NCT03182621 Not Applicable
9 Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children Completed NCT02295072 Not Applicable
10 System-IGF-1 Pathway and Alzheimer's Disease Completed NCT00647478
11 Effects of Physical and Cognitive Training in Neuroplasticity, Health and Cognition. Movement Project Recruiting NCT03123900 Not Applicable
12 Physical Exercise for Education ('Fit to Study') Active, not recruiting NCT03286725 Not Applicable
13 Heart Rate Variability and Cognitive Load on Image-Based Virtual Reality Instructional Design in Otolaryngology Not yet recruiting NCT03501641 Not Applicable

Search NIH Clinical Center for Cognitive Function 1, Social

Genetic Tests for Cognitive Function 1, Social

Anatomical Context for Cognitive Function 1, Social

MalaCards organs/tissues related to Cognitive Function 1, Social:

41
Brain, Heart, Cortex, Testes, Prefrontal Cortex, Spinal Cord, Amygdala

Publications for Cognitive Function 1, Social

Articles related to Cognitive Function 1, Social:

(show top 50) (show all 226)
# Title Authors Year
1
Executive and social-cognitive determinants of environmental dependency syndrome in behavioral frontotemporal dementia. ( 29809029 )
2018
2
Resting state connectivity mediates the relationship between collectivism and social cognition. ( 29208492 )
2018
3
Normal Performance in Non-Visual Social Cognition Tasks in Women with Turner Syndrome. ( 29780353 )
2018
4
Subjective and Objective: Alexithymia and Social Cognition in Eating Disorders. ( 29916406 )
2018
5
The nature of social cognitive deficits in children and adults with Klinefelter syndrome (47,XXY). ( 29406610 )
2018
6
Differences in frontotemporal dysfunction during social and non-social cognition tasks between patients with autism spectrum disorder and schizophrenia. ( 29445197 )
2018
7
Variation in the Oxytocin Receptor Gene Is Associated With Social Cognition and ADHD. ( 28478728 )
2017
8
Neuro-cognition and social cognition elements of social functioning and social quality of life. ( 28916297 )
2017
9
Variation in mothers' arginine vasopressin receptor 1a and dopamine receptor D4 genes predicts maternal sensitivity via social cognition. ( 27581946 )
2017
10
Functional characterization of an oxytocin receptor gene variant (rs2268498) previously associated with social cognition by expression analysis in vitro and in human brain biopsy. ( 27421662 )
2017
11
Understanding Social Situations (USS): A proof-of-concept social-cognitive intervention targeting theory of mind and attributional bias in individuals with psychosis. ( 27281040 )
2017
12
Agreement between clients with schizophrenia and mental health workers on clients' social quality of life: The role of social cognition and symptoms. ( 27435825 )
2017
13
Social cognition and aggression in methamphetamine dependence with and without a history of psychosis. ( 29224181 )
2017
14
On the relationships between DSM-5 dysfunctional personality traits and social cognition deficits: A study in a sample of consecutively admitted Italian psychotherapy patients. ( 28493518 )
2017
15
Deficits in Social Cognition: An Unveiled Signature of Multiple Sclerosis. ( 28069095 )
2017
16
Social Cognition Deficits: Current Position and Future Directions for Neuropsychological Interventions in Cerebrovascular Disease. ( 28729755 )
2017
17
Nonmotor Symptoms in Parkinson Disease: A Descriptive Review on Social Cognition Ability. ( 28073327 )
2017
18
Social Behavior and Impairments in Social Cognition Following Traumatic Brain Injury. ( 28399953 )
2017
19
Longitudinal associations of social cognition and substance use in childhood and early adolescence: findings from the Avon Longitudinal Study of Parents and Children. ( 29058116 )
2017
20
Interaction Between Val158Met Catechol-O-Methyltransferase Polymorphism and Social Cognitive Functioning in Schizophrenia: Pilot Study. ( 28856668 )
2017
21
Phenotypic continuum between autism and schizophrenia: Evidence from the Movie for the Assessment of Social Cognition (MASC). ( 28089135 )
2017
22
Social Cognition in Children Born Preterm: A Perspective on Future Research Directions. ( 28611695 )
2017
23
Social cognition and the course of social functioning in first-episode psychosis. ( 28402046 )
2017
24
Social cognitive predictors of treatment outcome in cannabis dependence. ( 27883947 )
2017
25
The positive link between executive function and lifetime cannabis use in schizophrenia is not explained by current levels of superior social cognition. ( 28152399 )
2017
26
Disconnection as a mechanism for social cognition impairment in multiple sclerosis. ( 28566550 )
2017
27
Social Cognition Abilities in Patients With Different Multiple Sclerosis Subtypes. ( 28656885 )
2017
28
Treatment of social cognition in schizophrenia: Current status and future directions. ( 28712968 )
2017
29
How children's victimization relates to distorted versus sensitive social cognition: Perception, mood, and need fulfillment in response to Cyberball inclusion and exclusion. ( 27875750 )
2017
30
Treatment seeking in cannabis dependence: The role of social cognition. ( 27894043 )
2017
31
Exploring social cognition in schizophrenia. ( 27838738 )
2017
32
The Effect of Age, Race, and Sex on Social Cognitive Performance in Individuals With Schizophrenia. ( 28141631 )
2017
33
Contrasting metacognitive, social cognitive and alexithymia profiles in adults with borderline personality disorder, schizophrenia and substance use disorder. ( 28826064 )
2017
34
Validation of the Movie for the Assessment of Social Cognition in Adolescents with ASD: Fixation Duration and Pupil Dilation as Predictors of Performance. ( 27271932 )
2016
35
Social-cognitive functioning and social skills in patients with early treated phenylketonuria: a PKU-COBESO study. ( 26914933 )
2016
36
Emotional intelligence and non-social cognition in schizophrenia and bipolar I disorder. ( 27640523 )
2016
37
Oxytocin, but not vasopressin, impairs social cognitive ability among individuals with higher levels of social anxiety: a randomized controlled trial. ( 27053769 )
2016
38
Cognitive Impairment Involving Social Cognition in SPG4 Hereditary Spastic Paraplegia. ( 27688599 )
2016
39
Social cognition in normal and pathological aging. ( 27976623 )
2016
40
Alexithymia in Adolescents with Autism Spectrum Disorder: Its Relationship to Internalising Difficulties, Sensory Modulation and Social Cognition. ( 26659552 )
2016
41
A prosocial online game for social cognition training in adolescents with high-functioning autism: an fMRI study. ( 27051288 )
2016
42
The effects of cigarette smoking behavior and psychosis history on general and social cognition in bipolar disorder. ( 27650399 )
2016
43
Social cognition in Intermittent Explosive Disorder and aggression. ( 27621104 )
2016
44
A review of the relation between dissociation, memory, executive functioning and social cognition in military members and civilians with neuropsychiatric conditions. ( 27444881 )
2016
45
First empirical evaluation of the link between attachment, social cognition and borderline features in adolescents. ( 26298843 )
2016
46
Mentalizing the body: spatial and social cognition in anosognosia for hemiplegia. ( 26811254 )
2016
47
Intact social cognitive processes in outpatients with anorexia nervosa: a pilot study. ( 27594894 )
2016
48
Are There Differences in Neurocognition and Social Cognition Among Adolescents with Schizophrenia, a Pervasive Developmental Disorder, and Both Disorders? ( 27015370 )
2016
49
Social cognition makes an independent contribution to peer relations in children with Specific Language Impairment. ( 26745788 )
2016
50
Deficits in social cognition in first episode psychosis: A review of the literature. ( 27771557 )
2016

Variations for Cognitive Function 1, Social

Expression for Cognitive Function 1, Social

Search GEO for disease gene expression data for Cognitive Function 1, Social.

Pathways for Cognitive Function 1, Social

GO Terms for Cognitive Function 1, Social

Sources for Cognitive Function 1, Social

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....