MCID: CLC053
MIFTS: 21

Colchicine Poisoning

Categories: Rare diseases

Aliases & Classifications for Colchicine Poisoning

Summaries for Colchicine Poisoning

MalaCards based summary : Colchicine Poisoning is related to familial mediterranean fever and wallerian degeneration. An important gene associated with Colchicine Poisoning is TUBB1 (Tubulin Beta 1 Class VI). Affiliated tissues include heart, and related phenotypes are hypotension and reduced consciousness/confusion

Related Diseases for Colchicine Poisoning

Diseases related to Colchicine Poisoning via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 familial mediterranean fever 9.9
2 wallerian degeneration 9.9

Symptoms & Phenotypes for Colchicine Poisoning

Human phenotypes related to Colchicine Poisoning:

59 32 (show all 29)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hypotension 59 32 hallmark (90%) Very frequent (99-80%) HP:0002615
2 reduced consciousness/confusion 59 32 frequent (33%) Frequent (79-30%) HP:0004372
3 renal insufficiency 59 32 frequent (33%) Frequent (79-30%) HP:0000083
4 dehydration 59 32 hallmark (90%) Very frequent (99-80%) HP:0001944
5 vomiting 59 32 hallmark (90%) Very frequent (99-80%) HP:0002013
6 hypophosphatemia 59 32 frequent (33%) Frequent (79-30%) HP:0002148
7 hypokalemia 59 32 frequent (33%) Frequent (79-30%) HP:0002900
8 arrhythmia 59 32 frequent (33%) Frequent (79-30%) HP:0011675
9 respiratory distress 59 32 hallmark (90%) Very frequent (99-80%) HP:0002098
10 congestive heart failure 59 32 frequent (33%) Frequent (79-30%) HP:0001635
11 alopecia 59 32 occasional (7.5%) Occasional (29-5%) HP:0001596
12 lactic acidosis 59 32 frequent (33%) Frequent (79-30%) HP:0003128
13 hypocalcemia 59 32 frequent (33%) Frequent (79-30%) HP:0002901
14 leukocytosis 59 32 hallmark (90%) Very frequent (99-80%) HP:0001974
15 hyponatremia 59 32 frequent (33%) Frequent (79-30%) HP:0002902
16 diarrhea 59 32 frequent (33%) Frequent (79-30%) HP:0002014
17 myocarditis 59 32 frequent (33%) Frequent (79-30%) HP:0012819
18 metabolic acidosis 59 32 hallmark (90%) Very frequent (99-80%) HP:0001942
19 hypovolemia 59 32 frequent (33%) Frequent (79-30%) HP:0011106
20 oliguria 59 32 frequent (33%) Frequent (79-30%) HP:0100520
21 nausea 59 32 hallmark (90%) Very frequent (99-80%) HP:0002018
22 hypomagnesemia 59 32 frequent (33%) Frequent (79-30%) HP:0002917
23 cardiorespiratory arrest 59 32 frequent (33%) Frequent (79-30%) HP:0006543
24 cardiogenic shock 59 32 frequent (33%) Frequent (79-30%) HP:0030149
25 acute encephalopathy 59 32 frequent (33%) Frequent (79-30%) HP:0006846
26 disseminated intravascular coagulation 59 32 frequent (33%) Frequent (79-30%) HP:0005521
27 abnormality of blood and blood-forming tissues 59 Frequent (79-30%)
28 abnormality of ion homeostasis 59 Frequent (79-30%)
29 abnormality of acid-base homeostasis 59 Frequent (79-30%)

Drugs & Therapeutics for Colchicine Poisoning

Search Clinical Trials , NIH Clinical Center for Colchicine Poisoning

Genetic Tests for Colchicine Poisoning

Anatomical Context for Colchicine Poisoning

MalaCards organs/tissues related to Colchicine Poisoning:

41
Heart

Publications for Colchicine Poisoning

Articles related to Colchicine Poisoning:

(show all 35)
# Title Authors Year
1
Evaluation of the Colchicine Poisoning Cases in a Pediatric Intensive Care Unit: Five Year Study. ( 27727039 )
2016
2
Anagen Effluvium Following Acute Colchicine Poisoning. ( 28442873 )
2016
3
Assessment of 17 Pediatric Cases With Colchicine Poisoning in a 2-Year Period. ( 26928096 )
2016
4
Extracorporeal life support in the treatment of colchicine poisoning. ( 26230148 )
2015
5
Rugged and accurate quantitation of colchicine in human plasma to support colchicine poisoning monitoring by using turbulent-flow LC-MS/MS analysis. ( 24295116 )
2013
6
Fatal colchicine poisoning by accidental ingestion of Colchicum persicum: a case report. ( 24196723 )
2013
7
Colchicine poisoning: defusing the ticking time bomb. ( 23474521 )
2013
8
Colchicine poisoning: a case report and review of literature. ( 22941521 )
2012
9
Colchicine poisoning: the dark side of an ancient drug. ( 20586571 )
2010
10
Colchicine poisoning in a very young child. ( 17013492 )
2006
11
Fatal colchicine poisoning by accidental ingestion of meadow saffron-case report. ( 15749368 )
2005
12
Accidental intravenous colchicine poisoning. ( 15570196 )
2004
13
Accidental colchicine poisoning in a dog. ( 14992256 )
2004
14
Colchicine poisoning: case report of two suicides. ( 15240048 )
2004
15
Four children with colchicine poisoning. ( 15311853 )
2004
16
Colchicine poisoning resulting from accidental ingestion of meadow saffron (Colchicum autumnale). ( 12455670 )
2002
17
Colchicine poisoning: case report of two homicides. ( 11394761 )
2001
18
Colchicine poisoning by accidental ingestion of meadow saffron (Colchicum autumnale): pathological and medicolegal aspects. ( 10680067 )
1999
19
Colchicine poisoning: report of a fatal case with body fluid and post-mortem tissue analysis by high-performance liquid chromatography. ( 10375125 )
1999
20
Colchicine poisoning: report of a fatal case and presentation of an HPLC procedure for body fluid and tissue analyses. ( 9013296 )
1997
21
Granulocyte-colony stimulating factor in the treatment of colchicine poisoning. ( 9154449 )
1997
22
Death following colchicine poisoning. ( 8113710 )
1994
23
Colchicine poisoning. ( 8207152 )
1994
24
Outpatient colchicine poisoning. ( 8467932 )
1993
25
Colchicine poisoning: report of a fatal case with body fluid analysis by GC/MS and histopathologic examination of postmortem tissues. ( 1943060 )
1991
26
Achilles and his evil squeeze. Colchicine poisoning. ( 1745297 )
1991
27
Dose-dependent reversal of acute murine colchicine poisoning by goat colchicine-specific Fab fragments. ( 1891780 )
1991
28
Acute colchicine poisoning presenting as symptomatic hypocalcaemia. ( 6487935 )
1984
29
Haemodynamic studies in eight cases of acute colchicine poisoning. ( 6862460 )
1983
30
Colchicine poisoning as a mode of suicide. ( 7175475 )
1982
31
Proposed mechanism for colchicine poisoning of microtubules reassembled in vitro from Strongylocentrotus purpuratus sperm tail outer doublet tubulin. ( 7397118 )
1980
32
Fatal colchicine poisoning in a boy with familial Mediterranean fever. ( 484593 )
1979
33
Addition of colchicine--tubulin complex to microtubule ends: the mechanism of substoichiometric colchicine poisoning. ( 269406 )
1977
34
Colchicine poisoning following ingestion of Gloriosa Superba tubers. ( 4693992 )
1973
35
Colchicine poisoning in relation to Hemerocallis and some other plants. ( 15396742 )
1949

Variations for Colchicine Poisoning

Expression for Colchicine Poisoning

Search GEO for disease gene expression data for Colchicine Poisoning.

Pathways for Colchicine Poisoning

GO Terms for Colchicine Poisoning

Sources for Colchicine Poisoning

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9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
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28 GO
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33 ICD10
34 ICD10 via Orphanet
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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