MCID: CLC053
MIFTS: 20

Colchicine Poisoning

Categories: Rare diseases

Aliases & Classifications for Colchicine Poisoning

Summaries for Colchicine Poisoning

MalaCards based summary : Colchicine Poisoning is related to familial mediterranean fever and wallerian degeneration. An important gene associated with Colchicine Poisoning is TUBB1 (Tubulin Beta 1 Class VI). Affiliated tissues include heart, and related phenotypes are hypotension and dehydration

Related Diseases for Colchicine Poisoning

Diseases related to Colchicine Poisoning via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 familial mediterranean fever 9.9
2 wallerian degeneration 9.9

Symptoms & Phenotypes for Colchicine Poisoning

Human phenotypes related to Colchicine Poisoning:

60 33 (show all 29)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hypotension 60 33 hallmark (90%) Very frequent (99-80%) HP:0002615
2 dehydration 60 33 hallmark (90%) Very frequent (99-80%) HP:0001944
3 vomiting 60 33 hallmark (90%) Very frequent (99-80%) HP:0002013
4 respiratory distress 60 33 hallmark (90%) Very frequent (99-80%) HP:0002098
5 leukocytosis 60 33 hallmark (90%) Very frequent (99-80%) HP:0001974
6 metabolic acidosis 60 33 hallmark (90%) Very frequent (99-80%) HP:0001942
7 nausea 60 33 hallmark (90%) Very frequent (99-80%) HP:0002018
8 reduced consciousness/confusion 60 33 frequent (33%) Frequent (79-30%) HP:0004372
9 renal insufficiency 60 33 frequent (33%) Frequent (79-30%) HP:0000083
10 hypophosphatemia 60 33 frequent (33%) Frequent (79-30%) HP:0002148
11 hypokalemia 60 33 frequent (33%) Frequent (79-30%) HP:0002900
12 arrhythmia 60 33 frequent (33%) Frequent (79-30%) HP:0011675
13 congestive heart failure 60 33 frequent (33%) Frequent (79-30%) HP:0001635
14 lactic acidosis 60 33 frequent (33%) Frequent (79-30%) HP:0003128
15 hypocalcemia 60 33 frequent (33%) Frequent (79-30%) HP:0002901
16 hyponatremia 60 33 frequent (33%) Frequent (79-30%) HP:0002902
17 diarrhea 60 33 frequent (33%) Frequent (79-30%) HP:0002014
18 myocarditis 60 33 frequent (33%) Frequent (79-30%) HP:0012819
19 hypovolemia 60 33 frequent (33%) Frequent (79-30%) HP:0011106
20 oliguria 60 33 frequent (33%) Frequent (79-30%) HP:0100520
21 acute encephalopathy 60 33 frequent (33%) Frequent (79-30%) HP:0006846
22 hypomagnesemia 60 33 frequent (33%) Frequent (79-30%) HP:0002917
23 disseminated intravascular coagulation 60 33 frequent (33%) Frequent (79-30%) HP:0005521
24 cardiorespiratory arrest 60 33 frequent (33%) Frequent (79-30%) HP:0006543
25 cardiogenic shock 60 33 frequent (33%) Frequent (79-30%) HP:0030149
26 alopecia 60 33 occasional (7.5%) Occasional (29-5%) HP:0001596
27 abnormality of blood and blood-forming tissues 60 Frequent (79-30%)
28 abnormality of ion homeostasis 60 Frequent (79-30%)
29 abnormality of acid-base homeostasis 60 Frequent (79-30%)

Drugs & Therapeutics for Colchicine Poisoning

Search Clinical Trials , NIH Clinical Center for Colchicine Poisoning

Genetic Tests for Colchicine Poisoning

Anatomical Context for Colchicine Poisoning

MalaCards organs/tissues related to Colchicine Poisoning:

42
Heart

Publications for Colchicine Poisoning

Articles related to Colchicine Poisoning:

(show all 35)
# Title Authors Year
1
Evaluation of the Colchicine Poisoning Cases in a Pediatric Intensive Care Unit: Five Year Study. ( 27727039 )
2017
2
Assessment of 17 Pediatric Cases With Colchicine Poisoning in a 2-Year Period. ( 26928096 )
2016
3
Anagen Effluvium Following Acute Colchicine Poisoning. ( 28442873 )
2016
4
Extracorporeal life support in the treatment of colchicine poisoning. ( 26230148 )
2015
5
Colchicine poisoning: defusing the ticking time bomb. ( 23474521 )
2013
6
Fatal colchicine poisoning by accidental ingestion of Colchicum persicum: a case report. ( 24196723 )
2013
7
Rugged and accurate quantitation of colchicine in human plasma to support colchicine poisoning monitoring by using turbulent-flow LC-MS/MS analysis. ( 24295116 )
2013
8
Colchicine poisoning: a case report and review of literature. ( 22941521 )
2012
9
Colchicine poisoning: the dark side of an ancient drug. ( 20586571 )
2010
10
Colchicine poisoning in a very young child. ( 17013492 )
2006
11
Fatal colchicine poisoning by accidental ingestion of meadow saffron-case report. ( 15749368 )
2005
12
Accidental colchicine poisoning in a dog. ( 14992256 )
2004
13
Colchicine poisoning: case report of two suicides. ( 15240048 )
2004
14
Four children with colchicine poisoning. ( 15311853 )
2004
15
Accidental intravenous colchicine poisoning. ( 15570196 )
2004
16
Colchicine poisoning resulting from accidental ingestion of meadow saffron (Colchicum autumnale). ( 12455670 )
2002
17
Colchicine poisoning: case report of two homicides. ( 11394761 )
2001
18
Colchicine poisoning: report of a fatal case with body fluid and post-mortem tissue analysis by high-performance liquid chromatography. ( 10375125 )
1999
19
Colchicine poisoning by accidental ingestion of meadow saffron (Colchicum autumnale): pathological and medicolegal aspects. ( 10680067 )
1999
20
Colchicine poisoning: report of a fatal case and presentation of an HPLC procedure for body fluid and tissue analyses. ( 9013296 )
1997
21
Granulocyte-colony stimulating factor in the treatment of colchicine poisoning. ( 9154449 )
1997
22
Death following colchicine poisoning. ( 8113710 )
1994
23
Colchicine poisoning. ( 8207152 )
1994
24
Outpatient colchicine poisoning. ( 8467932 )
1993
25
Achilles and his evil squeeze. Colchicine poisoning. ( 1745297 )
1991
26
Dose-dependent reversal of acute murine colchicine poisoning by goat colchicine-specific Fab fragments. ( 1891780 )
1991
27
Colchicine poisoning: report of a fatal case with body fluid analysis by GC/MS and histopathologic examination of postmortem tissues. ( 1943060 )
1991
28
Acute colchicine poisoning presenting as symptomatic hypocalcaemia. ( 6487935 )
1984
29
Haemodynamic studies in eight cases of acute colchicine poisoning. ( 6862460 )
1983
30
Colchicine poisoning as a mode of suicide. ( 7175475 )
1982
31
Proposed mechanism for colchicine poisoning of microtubules reassembled in vitro from Strongylocentrotus purpuratus sperm tail outer doublet tubulin. ( 7397118 )
1980
32
Fatal colchicine poisoning in a boy with familial Mediterranean fever. ( 484593 )
1979
33
Addition of colchicine--tubulin complex to microtubule ends: the mechanism of substoichiometric colchicine poisoning. ( 269406 )
1977
34
Colchicine poisoning following ingestion of Gloriosa Superba tubers. ( 4693992 )
1973
35
Colchicine poisoning in relation to Hemerocallis and some other plants. ( 15396742 )
1949

Variations for Colchicine Poisoning

Expression for Colchicine Poisoning

Search GEO for disease gene expression data for Colchicine Poisoning.

Pathways for Colchicine Poisoning

GO Terms for Colchicine Poisoning

Sources for Colchicine Poisoning

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....