Colloid Carcinoma of the Pancreas disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Colloid Carcinoma of the Pancreas

MalaCards integrated aliases for Colloid Carcinoma of the Pancreas:

Name: Colloid Carcinoma of the Pancreas ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7717

NCIt ⁵⁰ C37214

UMLS ⁷³ C1333081

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Summaries for Colloid Carcinoma of the Pancreas

MalaCards based summary : Colloid Carcinoma of the Pancreas is related to pseudomyxoma peritonei and tumor of exocrine pancreas. An important gene associated with Colloid Carcinoma of the Pancreas is PSCA (Prostate Stem Cell Antigen), and among its related pathways/superpathways are Gastric cancer and Development EGFR signaling pathway. Affiliated tissues include pancreas, lung and liver, and related phenotypes are cellular and growth/size/body region

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Related Diseases for Colloid Carcinoma of the Pancreas

Diseases related to Colloid Carcinoma of the Pancreas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)

#	Related Disease	Score	Top Affiliating Genes
1	pseudomyxoma peritonei	30.0	KRAS MUC1 MUC2 MUC5AC
2	tumor of exocrine pancreas	10.2	MUC1 MUC2
3	pancreatic intraductal papillary-mucinous neoplasm	10.2	MUC1 MUC2
4	sigmoid neoplasm	10.2	HRAS KRAS
5	syringocystadenoma papilliferum	10.2	KRAS MUC1
6	duodenum adenocarcinoma	10.2	KRAS MUC2
7	paronychia	10.2	HRAS KRAS
8	cystadenocarcinoma	10.2	HRAS MUC1 MUC2
9	duodenal disease	10.2	KRAS MUC1 MUC2
10	familial colorectal cancer type x	10.2	BRCA2 SMAD4
11	pancreatic ductal carcinoma	10.2	MUC1 MUC2 SMAD4
12	schimmelpenning-feuerstein-mims syndrome	10.2	HRAS KRAS
13	mucinous adenocarcinoma	10.2	KRAS MUC1 MUC2
14	mutyh-associated polyposis	10.2	KRAS SMAD4
15	ampulla of vater adenocarcinoma	10.2	BRCA2 MUC1 MUC2
16	bile duct cysts	10.2	HRAS KRAS
17	apocrine adenoma	10.2	HRAS KRAS MUC1
18	appendix disease	10.2	HRAS KRAS MUC2
19	mucinous intrahepatic cholangiocarcinoma	10.2	MUC2 MUC5AC
20	aggressive digital papillary adenocarcinoma	10.2	HRAS KRAS MUC1
21	intestinal benign neoplasm	10.2	HRAS KRAS MUC2
22	cap polyposis	10.2	MUC2 MUC5AC
23	small intestine cancer	10.2	HRAS KRAS MUC2
24	carcinosarcoma	10.1	HRAS KRAS MUC1
25	colorectal adenocarcinoma	10.1	HRAS KRAS MUC2
26	breast mucoepidermoid carcinoma	10.1	MUC1 MUC5AC
27	solid adenocarcinoma with mucin production	10.1	MUC1 MUC5AC
28	pancreas disease	10.1	HRAS KRAS SMAD4
29	lung adenoid cystic carcinoma	10.1	HRAS KRAS
30	intestinal disease	10.1	HRAS KRAS MUC2
31	mucoepidermoid carcinoma	10.1	MUC1 MUC2 MUC5AC
32	nasal cavity adenocarcinoma	10.1	HRAS KRAS
33	bile duct cystadenocarcinoma	10.1	MUC1 MUC2 MUC5AC
34	mucinous tubular and spindle renal cell carcinoma	10.1	KRT19 MUC1 MUC2
35	meconium ileus	10.1	MUC1 MUC2 MUC5AC
36	clear cell adenoma	10.1	MUC2 MUC5AC
37	gastric tubular adenocarcinoma	10.1	MUC1 MUC2 MUC5AC
38	duodenum cancer	10.1	HRAS KRAS MUC1 MUC2
39	ampulla of vater cancer	10.1	HRAS KRAS MUC1 MUC2
40	hodgkin's lymphoma, lymphocytic depletion	10.1	FSCN1 FSCN3
41	gastric cardia carcinoma	10.1	MUC1 MUC5AC SMAD4
42	adenocarcinoma	10.1	HRAS KRAS MUC1 SMAD4
43	cryptogenic organizing pneumonia	10.1	MUC1 MUC5B
44	otitis media	10.1	MUC2 MUC5AC MUC5B
45	anal gland adenocarcinoma	10.1	KRT19 MUC5AC
46	lynch syndrome	10.1	BRCA2 KRAS MUC2
47	liver angiosarcoma	10.0	HRAS KRAS KRT19
48	anus adenocarcinoma	10.0	KRT19 MUC5AC
49	cystitis cystica	10.0	FSCN1 MUC2 MUC5AC
50	bile duct mucoepidermoid carcinoma	10.0	MUC1 MUC2 MUC5AC MUC5B

Graphical network of the top 20 diseases related to Colloid Carcinoma of the Pancreas:

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Symptoms & Phenotypes for Colloid Carcinoma of the Pancreas

MGI Mouse Phenotypes related to Colloid Carcinoma of the Pancreas:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cellular	MP:0005384	10.18	BRCA2 FSCN1 GGT1 KRAS KRT19 MUC2
2	growth/size/body region	MP:0005378	10.14	BRCA2 FSCN1 GGT1 HRAS KRAS KRT19
3	digestive/alimentary	MP:0005381	10.11	BRCA2 HRAS KRAS KRT19 MUC2 MUC5AC
4	endocrine/exocrine gland	MP:0005379	10.09	BRCA2 GGT1 HRAS KRAS KRT19 MUC2
5	immune system	MP:0005387	10.06	BRCA2 FSCN1 GGT1 KRAS MUC2 MUC5AC
6	hematopoietic system	MP:0005397	10.02	BRCA2 GGT1 KRAS MUC2 MUC5B PHEX
7	mortality/aging	MP:0010768	9.9	BRCA2 FSCN1 GGT1 HRAS KRAS KRT19
8	limbs/digits/tail	MP:0005371	9.73	BRCA2 GGT1 KRAS PHEX SFN SMAD4
9	neoplasm	MP:0002006	9.56	BRCA2 HRAS KRAS KRT19 MUC2 PSCA
10	skeleton	MP:0005390	9.23	BRCA2 GGT1 HRAS KRAS KRT19 PHEX

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Drugs & Therapeutics for Colloid Carcinoma of the Pancreas

Search Clinical Trials , NIH Clinical Center for Colloid Carcinoma of the Pancreas

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Genetic Tests for Colloid Carcinoma of the Pancreas

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Anatomical Context for Colloid Carcinoma of the Pancreas

MalaCards organs/tissues related to Colloid Carcinoma of the Pancreas:

⁴¹

Pancreas, Lung, Liver, Breast, Ovary, Small Intestine, Appendix

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Publications for Colloid Carcinoma of the Pancreas

Articles related to Colloid Carcinoma of the Pancreas:

#	Title	Authors	Year
1	Pseudomyxoma peritonei associated with colloid carcinoma of the pancreas. ( 2998918 )	Chejfec G....Gould V.E.	1986

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Genes for Colloid Carcinoma of the Pancreas

Genes related to Colloid Carcinoma of the Pancreas (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PSCA	Prostate Stem Cell Antigen	Protein Coding	14.64	DISEASES inferred ¹⁵
2	MUC2	Mucin 2, Oligomeric Mucus/Gel-Forming	Protein Coding	14.33	DISEASES inferred ¹⁵
3	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	14.2	DISEASES inferred ¹⁵
4	MUC5B	Mucin 5B, Oligomeric Mucus/Gel-Forming	Protein Coding	14.1	DISEASES inferred ¹⁵
5	PHEX	Phosphate Regulating Endopeptidase Homolog X-Linked	Protein Coding	13.96	DISEASES inferred ¹⁵
6	SMAD4	SMAD Family Member 4	Protein Coding	13.66	DISEASES inferred ¹⁵
7	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	13.61	DISEASES inferred ¹⁵
8	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	13.47	DISEASES inferred ¹⁵
9	BRCA2	BRCA2, DNA Repair Associated	Protein Coding	13.04	DISEASES inferred ¹⁵
10	FSCN3	Fascin Actin-Bundling Protein 3	Protein Coding	4.75	DISEASES inferred ¹⁵
11	SFN	Stratifin	Protein Coding	4.59	DISEASES inferred ¹⁵
12	FSCN1	Fascin Actin-Bundling Protein 1	Protein Coding	4.35	DISEASES inferred ¹⁵
13	MSLN	Mesothelin	Protein Coding	4.3	DISEASES inferred ¹⁵
14	MUC5AC	Mucin 5AC, Oligomeric Mucus/Gel-Forming	Protein Coding	3.84	DISEASES inferred ¹⁵
15	GGT2	Gamma-Glutamyltransferase 2	Protein Coding	3.67	DISEASES inferred ¹⁵
16	GGT1	Gamma-Glutamyltransferase 1	Protein Coding	3.65	DISEASES inferred ¹⁵
17	KRT19	Keratin 19	Protein Coding	3.5	DISEASES inferred ¹⁵

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Variations for Colloid Carcinoma of the Pancreas

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Expression for Colloid Carcinoma of the Pancreas

Search GEO for disease gene expression data for Colloid Carcinoma of the Pancreas.

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Pathways for Colloid Carcinoma of the Pancreas

Pathways related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

(show all 14)

#	Super pathways	Score	Top Affiliating Genes
1	Gastric cancer ³⁷ Show member pathways Breast cancer ³⁷ Hepatocellular carcinoma ³⁷	12.47	BRCA2 HRAS KRAS MUC2 SMAD4
2	Development EGFR signaling pathway ²² Show member pathways Development ERBB-family signaling ²² EGF Pathway ⁶⁴ EGFR Signaling Pathway ⁶⁷ ErbB receptor signaling network ¹	12.26	HRAS KRAS MUC1 SMAD4
3	O-linked glycosylation ⁶⁶ Show member pathways O-linked glycosylation of mucins ⁶⁶	11.93	MUC1 MUC2 MUC5AC MUC5B
4	IL-1 Family Signaling Pathways ⁶⁵ Show member pathways Immune response IL-1 signaling pathway ²² Mucin expression in CF via TLRs, EGFR signaling pathways ²²	11.87	HRAS MUC2 MUC5AC MUC5B
5	DNA Damage Response (only ATM dependent) ¹	11.75	HRAS KRAS SMAD4
6	MAP Kinase Signaling ⁴	11.72	HRAS KRAS SFN
7	Diseases of glycosylation ⁶⁶ Show member pathways Diseases associated with O-glycosylation of proteins ⁶⁶	11.72	MUC1 MUC2 MUC5AC MUC5B
8	AGE-RAGE signaling pathway in diabetic complications ³⁷	11.63	HRAS KRAS SMAD4
9	CLEC7A (Dectin-1) signaling ⁶⁶ Show member pathways Alternative NF-kappaB pathway ¹ CLEC7A/inflammasome pathway ⁶⁶ C-type lectin receptors (CLRs) ⁶⁶	11.51	HRAS KRAS MUC1 MUC2 MUC5AC MUC5B
10	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) ⁶⁶ Show member pathways Dectin-2 family ⁶⁶ Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) ⁶⁶ Defective GALNT12 causes colorectal cancer 1 (CRCS1) ⁶⁶ Termination of O-glycan biosynthesis ⁶⁶	11.29	MUC1 MUC2 MUC5AC MUC5B
11	NTHi-Induced Signaling ⁶⁴	10.86	MUC2 SMAD4
12	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling ¹	10.83	HRAS KRAS
13	Extracellular vesicle-mediated signaling in recipient cells ¹	10.81	HRAS KRAS SMAD4
14	p38MAPK events ⁶⁶	10.55	HRAS KRAS

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GO Terms for Colloid Carcinoma of the Pancreas

Cellular components related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	plasma membrane	GO:0005886	9.9	GGT1 HRAS KRAS KRT19 MSLN MUC1
2	extracellular exosome	GO:0070062	9.61	FSCN1 GGT1 GGT2 KRT19 MUC1 MUC5AC
3	Golgi lumen	GO:0005796	8.92	MUC1 MUC2 MUC5AC MUC5B

Biological processes related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

(show all 12)

#	Name	GO ID	Score	Top Affiliating Genes
1	response to estradiol	GO:0032355	9.65	BRCA2 GGT1 GGT2
2	glutamate metabolic process	GO:0006536	9.51	GGT1 GGT2
3	zymogen activation	GO:0031638	9.49	GGT1 GGT2
4	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	GO:0006978	9.46	BRCA2 MUC1
5	glutathione catabolic process	GO:0006751	9.43	GGT1 GGT2
6	leukotriene D4 biosynthetic process	GO:1901750	9.4	GGT1 GGT2
7	cysteine biosynthetic process	GO:0019344	9.37	GGT1 GGT2
8	response to isolation stress	GO:0035900	9.32	HRAS KRAS
9	regulation of immune system process	GO:0002682	9.26	GGT1 GGT2
10	O-glycan processing	GO:0016266	9.26	MUC1 MUC2 MUC5AC MUC5B
11	peptide modification	GO:0031179	9.16	GGT1 GGT2
12	stimulatory C-type lectin receptor signaling pathway	GO:0002223	9.1	HRAS KRAS MUC1 MUC2 MUC5AC MUC5B

Molecular functions related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	glutathione hydrolase activity	GO:0036374	8.96	GGT1 GGT2
2	peptidyltransferase activity	GO:0000048	8.62	GGT1 GGT2

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