Colloid Carcinoma of the Pancreas disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Colloid Carcinoma of the Pancreas

MalaCards integrated aliases for Colloid Carcinoma of the Pancreas:

Name: Colloid Carcinoma of the Pancreas ¹² ¹⁵

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:7717

NCIt ⁴⁹ C37214

UMLS ⁷¹ C1333081

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Summaries for Colloid Carcinoma of the Pancreas

MalaCards based summary : Colloid Carcinoma of the Pancreas is related to pseudomyxoma peritonei and adenocarcinoma. An important gene associated with Colloid Carcinoma of the Pancreas is MUC5B (Mucin 5B, Oligomeric Mucus/Gel-Forming), and among its related pathways/superpathways are CLEC7A (Dectin-1) signaling and O-linked glycosylation. Affiliated tissues include pancreas, and related phenotype is immune system.

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Related Diseases for Colloid Carcinoma of the Pancreas

Diseases related to Colloid Carcinoma of the Pancreas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)

#	Related Disease	Score	Top Affiliating Genes
1	pseudomyxoma peritonei	29.8	MUC5AC MUC1
2	adenocarcinoma	10.1
3	interstitial pneumonitis, desquamative, familial	10.1	MUC5B MUC1
4	ovarian mucinous neoplasm	10.0	PSCA MUC5AC
5	mucinous adenocarcinoma	10.0	MUC5AC MUC1
6	status asthmaticus	10.0	MUC5B MUC5AC
7	mucoepidermoid carcinoma	10.0	MUC5AC MUC1
8	nonspecific interstitial pneumonia	10.0	MUC5B MUC1
9	urinary bladder villous adenoma	10.0	MUC5AC MUC1
10	villous adenoma	10.0	MUC5AC MUC1
11	mucinous intrahepatic cholangiocarcinoma	10.0	MUC5AC MUC1
12	intrahepatic cholangiocarcinoma	10.0	MUC5AC MUC1
13	bile duct cystadenocarcinoma	10.0	MUC5AC MUC1
14	cystadenocarcinoma	10.0	MUC5AC MUC1
15	biliary tract benign neoplasm	10.0	MUC5AC MUC1
16	pancreatic mucinous cystadenoma	10.0	MUC5AC MUC1
17	cystadenoma	10.0	MUC5AC MUC1
18	middle ear disease	10.0	MUC5B MUC5AC
19	filamentary keratitis	10.0	MUC5AC MUC1
20	tumor of exocrine pancreas	10.0	MUC5AC MUC1
21	solid adenocarcinoma with mucin production	10.0	MUC5AC MUC1
22	colorectal cancer, hereditary nonpolyposis, type 8	10.0	MUC5AC MUC1
23	complete androgen insensitivity syndrome	10.0	MUC5AC MUC1
24	androgen insensitivity syndrome	10.0	MUC5AC MUC1
25	gastric diffuse adenocarcinoma	10.0	MUC5AC MUC1
26	meconium ileus	10.0	MUC5AC MUC1
27	paget disease, extramammary	10.0	MUC5AC MUC1
28	duodenum cancer	10.0	MUC5AC MUC1
29	duodenum disease	10.0	MUC5AC MUC1
30	ampulla of vater adenocarcinoma	9.9	MUC5AC MUC1
31	signet ring cell adenocarcinoma	9.9	MUC5AC MUC1
32	endocervical adenocarcinoma	9.9	MUC5AC MUC1
33	tubular adenocarcinoma	9.9	MUC5AC MUC1
34	ovarian cystadenocarcinoma	9.9	MUC5AC MUC1
35	small intestine cancer	9.9	MUC5AC MUC1
36	pancreatic ductal carcinoma	9.9	MUC5AC MUC1
37	cholecystitis	9.8	MUC5AC MUC1
38	ampulla of vater cancer	9.8	MUC5AC MUC1
39	dry eye syndrome	9.8	MUC5AC MUC1
40	ovary adenocarcinoma	9.8	MUC5AC MUC1
41	intrahepatic biliary papillomatosis	9.7	MUC5B MUC5AC MUC1
42	biliary papillomatosis	9.7	MUC5B MUC5AC MUC1
43	bile duct mucinous adenocarcinoma	9.7	MUC5B MUC5AC MUC1
44	bile duct mucoepidermoid carcinoma	9.7	MUC5B MUC5AC MUC1
45	chronic ethmoiditis	9.7	MUC5B MUC5AC MUC1
46	appendix disease	9.7	MUC5B MUC5AC MUC1
47	appendix cancer	9.7	MUC5B MUC5AC MUC1
48	colorectal cancer 1	9.7	MUC5B MUC5AC MUC1
49	pulmonary fibrosis, idiopathic	9.6	MUC5B MUC5AC MUC1
50	ductal carcinoma in situ	9.6	SFN MUC1

Graphical network of the top 20 diseases related to Colloid Carcinoma of the Pancreas:

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Symptoms & Phenotypes for Colloid Carcinoma of the Pancreas

MGI Mouse Phenotypes related to Colloid Carcinoma of the Pancreas:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	immune system	MP:0005387	9.02	MUC5AC MUC5B PHEX PSCA SFN

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Drugs & Therapeutics for Colloid Carcinoma of the Pancreas

Search Clinical Trials , NIH Clinical Center for Colloid Carcinoma of the Pancreas

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Genetic Tests for Colloid Carcinoma of the Pancreas

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Anatomical Context for Colloid Carcinoma of the Pancreas

MalaCards organs/tissues related to Colloid Carcinoma of the Pancreas:

⁴⁰

Pancreas

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Publications for Colloid Carcinoma of the Pancreas

Articles related to Colloid Carcinoma of the Pancreas:

(show all 11)

#	Title	Authors	PMID	Year
1	Colloid Carcinoma of the Pancreas: Case Report and Review of the Literature. ⁶¹	Orcutt ST...Hodul PJ	30631814	2016
2	Colloid carcinoma of the pancreas: a distinct pancreatic neoplasm with good prognosis. Report of a case. ⁶¹	Rubio-Perez I...Larranaga E	22406606	2012
3	[Colloid carcinoma of pancreas: a clinicopathologic study of 4 cases]. ⁶¹	Chang XY...Chen J	22336159	2011
4	Colloid carcinoma of the pancreas. ⁶¹	Plerhoples TA...Poultsides GA	21253833	2011
5	CT features of colloid carcinomas of the pancreas. ⁶¹	Ren FY...Lu JP	20529590	2010
6	MRI features of pancreatic colloid carcinoma. ⁶¹	Yoon MA...Lee MW	19770300	2009
7	Colloid carcinoma of the pancreas: review of selected pathological and clinical aspects. ⁶¹	Liszka L...Golka D	18985519	2008
8	Ductal neoplasia of the pancreas: nosologic, clinicopathologic, and biologic aspects. ⁶¹	Adsay NV...Andea AA	16183479	2005
9	Pathologic quiz case: a 52-year-old woman with jaundice and history of necrotizing pancreatitis. Primary colloid carcinoma of the pancreas. ⁶¹	Parwani AV...Ali SZ	15679436	2005
10	Pseudomyxoma peritonei associated with colloid carcinoma of the pancreas. ⁶¹	Chejfec G...Gould VE	2998918	1986
11	Colloid carcinoma of the pancreas. ⁶¹	MUIR EG	12987655	1952

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Genes for Colloid Carcinoma of the Pancreas

Genes related to Colloid Carcinoma of the Pancreas (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MUC5B	Mucin 5B, Oligomeric Mucus/Gel-Forming	Protein Coding	5.24	DISEASES inferred ¹⁵
2	PSCA	Prostate Stem Cell Antigen	Protein Coding	5.16	DISEASES inferred ¹⁵
3	MUC1	Mucin 1, Cell Surface Associated	Protein Coding	5.11	DISEASES inferred ¹⁵
4	SFN	Stratifin	Protein Coding	5.1	DISEASES inferred ¹⁵
5	PHEX	Phosphate Regulating Endopeptidase Homolog X-Linked	Protein Coding	5.05	DISEASES inferred ¹⁵
6	MUC5AC	Mucin 5AC, Oligomeric Mucus/Gel-Forming	Protein Coding	4.93	DISEASES inferred ¹⁵

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Variations for Colloid Carcinoma of the Pancreas

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Expression for Colloid Carcinoma of the Pancreas

Search GEO for disease gene expression data for Colloid Carcinoma of the Pancreas.

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Pathways for Colloid Carcinoma of the Pancreas

Pathways related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	CLEC7A (Dectin-1) signaling ⁶⁵ Show member pathways Alternative NF-kappaB pathway ¹ CLEC7A/inflammasome pathway ⁶⁵ C-type lectin receptors (CLRs) ⁶⁵	11.84	MUC5B MUC5AC MUC1
2	O-linked glycosylation ⁶⁵ Show member pathways O-linked glycosylation of mucins ⁶⁵	11.59	MUC5B MUC5AC MUC1
3	Diseases of glycosylation ⁶⁵ Show member pathways Diseases associated with O-glycosylation of proteins ⁶⁵	11.3	MUC5B MUC5AC MUC1
4	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) ⁶⁵ Show member pathways Dectin-2 family ⁶⁵ Defective GALNT12 causes colorectal cancer 1 (CRCS1) ⁶⁵ Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) ⁶⁵ Termination of O-glycan biosynthesis ⁶⁵	10.84	MUC5B MUC5AC MUC1

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GO Terms for Colloid Carcinoma of the Pancreas

Cellular components related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.56	SFN MUC5B MUC5AC MUC1
2	extracellular region	GO:0005576	9.55	SFN PSCA MUC5B MUC5AC MUC1
3	extracellular exosome	GO:0070062	9.35	SFN PSCA MUC5B MUC5AC MUC1
4	Golgi lumen	GO:0005796	8.8	MUC5B MUC5AC MUC1

Biological processes related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	GO:0006977	9.16	SFN MUC1
2	stimulatory C-type lectin receptor signaling pathway	GO:0002223	9.13	MUC5B MUC5AC MUC1
3	O-glycan processing	GO:0016266	8.8	MUC5B MUC5AC MUC1

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