MCID: CLL009
MIFTS: 32

Colloid Carcinoma of the Pancreas

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Colloid Carcinoma of the Pancreas

MalaCards integrated aliases for Colloid Carcinoma of the Pancreas:

Name: Colloid Carcinoma of the Pancreas 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:7717
NCIt 50 C37214
UMLS 73 C1333081

Summaries for Colloid Carcinoma of the Pancreas

MalaCards based summary : Colloid Carcinoma of the Pancreas is related to pseudomyxoma peritonei and tumor of exocrine pancreas. An important gene associated with Colloid Carcinoma of the Pancreas is PSCA (Prostate Stem Cell Antigen), and among its related pathways/superpathways are Gastric cancer and Development EGFR signaling pathway. Affiliated tissues include pancreas, lung and liver, and related phenotypes are cellular and growth/size/body region

Related Diseases for Colloid Carcinoma of the Pancreas

Diseases related to Colloid Carcinoma of the Pancreas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 97)
# Related Disease Score Top Affiliating Genes
1 pseudomyxoma peritonei 30.0 KRAS MUC1 MUC2 MUC5AC
2 tumor of exocrine pancreas 10.2 MUC1 MUC2
3 pancreatic intraductal papillary-mucinous neoplasm 10.2 MUC1 MUC2
4 sigmoid neoplasm 10.2 HRAS KRAS
5 syringocystadenoma papilliferum 10.2 KRAS MUC1
6 duodenum adenocarcinoma 10.2 KRAS MUC2
7 paronychia 10.2 HRAS KRAS
8 cystadenocarcinoma 10.2 HRAS MUC1 MUC2
9 duodenal disease 10.2 KRAS MUC1 MUC2
10 familial colorectal cancer type x 10.2 BRCA2 SMAD4
11 pancreatic ductal carcinoma 10.2 MUC1 MUC2 SMAD4
12 schimmelpenning-feuerstein-mims syndrome 10.2 HRAS KRAS
13 mucinous adenocarcinoma 10.2 KRAS MUC1 MUC2
14 mutyh-associated polyposis 10.2 KRAS SMAD4
15 ampulla of vater adenocarcinoma 10.2 BRCA2 MUC1 MUC2
16 bile duct cysts 10.2 HRAS KRAS
17 apocrine adenoma 10.2 HRAS KRAS MUC1
18 appendix disease 10.2 HRAS KRAS MUC2
19 mucinous intrahepatic cholangiocarcinoma 10.2 MUC2 MUC5AC
20 aggressive digital papillary adenocarcinoma 10.2 HRAS KRAS MUC1
21 intestinal benign neoplasm 10.2 HRAS KRAS MUC2
22 cap polyposis 10.2 MUC2 MUC5AC
23 small intestine cancer 10.2 HRAS KRAS MUC2
24 carcinosarcoma 10.1 HRAS KRAS MUC1
25 colorectal adenocarcinoma 10.1 HRAS KRAS MUC2
26 breast mucoepidermoid carcinoma 10.1 MUC1 MUC5AC
27 solid adenocarcinoma with mucin production 10.1 MUC1 MUC5AC
28 pancreas disease 10.1 HRAS KRAS SMAD4
29 lung adenoid cystic carcinoma 10.1 HRAS KRAS
30 intestinal disease 10.1 HRAS KRAS MUC2
31 mucoepidermoid carcinoma 10.1 MUC1 MUC2 MUC5AC
32 nasal cavity adenocarcinoma 10.1 HRAS KRAS
33 bile duct cystadenocarcinoma 10.1 MUC1 MUC2 MUC5AC
34 mucinous tubular and spindle renal cell carcinoma 10.1 KRT19 MUC1 MUC2
35 meconium ileus 10.1 MUC1 MUC2 MUC5AC
36 clear cell adenoma 10.1 MUC2 MUC5AC
37 gastric tubular adenocarcinoma 10.1 MUC1 MUC2 MUC5AC
38 duodenum cancer 10.1 HRAS KRAS MUC1 MUC2
39 ampulla of vater cancer 10.1 HRAS KRAS MUC1 MUC2
40 hodgkin's lymphoma, lymphocytic depletion 10.1 FSCN1 FSCN3
41 gastric cardia carcinoma 10.1 MUC1 MUC5AC SMAD4
42 adenocarcinoma 10.1 HRAS KRAS MUC1 SMAD4
43 cryptogenic organizing pneumonia 10.1 MUC1 MUC5B
44 otitis media 10.1 MUC2 MUC5AC MUC5B
45 anal gland adenocarcinoma 10.1 KRT19 MUC5AC
46 lynch syndrome 10.1 BRCA2 KRAS MUC2
47 liver angiosarcoma 10.0 HRAS KRAS KRT19
48 anus adenocarcinoma 10.0 KRT19 MUC5AC
49 cystitis cystica 10.0 FSCN1 MUC2 MUC5AC
50 bile duct mucoepidermoid carcinoma 10.0 MUC1 MUC2 MUC5AC MUC5B

Graphical network of the top 20 diseases related to Colloid Carcinoma of the Pancreas:



Diseases related to Colloid Carcinoma of the Pancreas

Symptoms & Phenotypes for Colloid Carcinoma of the Pancreas

MGI Mouse Phenotypes related to Colloid Carcinoma of the Pancreas:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.18 BRCA2 FSCN1 GGT1 KRAS KRT19 MUC2
2 growth/size/body region MP:0005378 10.14 BRCA2 FSCN1 GGT1 HRAS KRAS KRT19
3 digestive/alimentary MP:0005381 10.11 BRCA2 HRAS KRAS KRT19 MUC2 MUC5AC
4 endocrine/exocrine gland MP:0005379 10.09 BRCA2 GGT1 HRAS KRAS KRT19 MUC2
5 immune system MP:0005387 10.06 BRCA2 FSCN1 GGT1 KRAS MUC2 MUC5AC
6 hematopoietic system MP:0005397 10.02 BRCA2 GGT1 KRAS MUC2 MUC5B PHEX
7 mortality/aging MP:0010768 9.9 BRCA2 FSCN1 GGT1 HRAS KRAS KRT19
8 limbs/digits/tail MP:0005371 9.73 BRCA2 GGT1 KRAS PHEX SFN SMAD4
9 neoplasm MP:0002006 9.56 BRCA2 HRAS KRAS KRT19 MUC2 PSCA
10 skeleton MP:0005390 9.23 BRCA2 GGT1 HRAS KRAS KRT19 PHEX

Drugs & Therapeutics for Colloid Carcinoma of the Pancreas

Search Clinical Trials , NIH Clinical Center for Colloid Carcinoma of the Pancreas

Genetic Tests for Colloid Carcinoma of the Pancreas

Anatomical Context for Colloid Carcinoma of the Pancreas

MalaCards organs/tissues related to Colloid Carcinoma of the Pancreas:

41
Pancreas, Lung, Liver, Breast, Ovary, Small Intestine, Appendix

Publications for Colloid Carcinoma of the Pancreas

Articles related to Colloid Carcinoma of the Pancreas:

# Title Authors Year
1
Pseudomyxoma peritonei associated with colloid carcinoma of the pancreas. ( 2998918 )
1986

Variations for Colloid Carcinoma of the Pancreas

Expression for Colloid Carcinoma of the Pancreas

Search GEO for disease gene expression data for Colloid Carcinoma of the Pancreas.

Pathways for Colloid Carcinoma of the Pancreas

Pathways related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.47 BRCA2 HRAS KRAS MUC2 SMAD4
2
Show member pathways
12.26 HRAS KRAS MUC1 SMAD4
3
Show member pathways
11.93 MUC1 MUC2 MUC5AC MUC5B
4
Show member pathways
11.87 HRAS MUC2 MUC5AC MUC5B
5 11.75 HRAS KRAS SMAD4
6 11.72 HRAS KRAS SFN
7
Show member pathways
11.72 MUC1 MUC2 MUC5AC MUC5B
8 11.63 HRAS KRAS SMAD4
9
Show member pathways
11.51 HRAS KRAS MUC1 MUC2 MUC5AC MUC5B
10
Show member pathways
11.29 MUC1 MUC2 MUC5AC MUC5B
11 10.86 MUC2 SMAD4
12 10.83 HRAS KRAS
13 10.81 HRAS KRAS SMAD4
14 10.55 HRAS KRAS

GO Terms for Colloid Carcinoma of the Pancreas

Cellular components related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.9 GGT1 HRAS KRAS KRT19 MSLN MUC1
2 extracellular exosome GO:0070062 9.61 FSCN1 GGT1 GGT2 KRT19 MUC1 MUC5AC
3 Golgi lumen GO:0005796 8.92 MUC1 MUC2 MUC5AC MUC5B

Biological processes related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 response to estradiol GO:0032355 9.65 BRCA2 GGT1 GGT2
2 glutamate metabolic process GO:0006536 9.51 GGT1 GGT2
3 zymogen activation GO:0031638 9.49 GGT1 GGT2
4 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.46 BRCA2 MUC1
5 glutathione catabolic process GO:0006751 9.43 GGT1 GGT2
6 leukotriene D4 biosynthetic process GO:1901750 9.4 GGT1 GGT2
7 cysteine biosynthetic process GO:0019344 9.37 GGT1 GGT2
8 response to isolation stress GO:0035900 9.32 HRAS KRAS
9 regulation of immune system process GO:0002682 9.26 GGT1 GGT2
10 O-glycan processing GO:0016266 9.26 MUC1 MUC2 MUC5AC MUC5B
11 peptide modification GO:0031179 9.16 GGT1 GGT2
12 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.1 HRAS KRAS MUC1 MUC2 MUC5AC MUC5B

Molecular functions related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutathione hydrolase activity GO:0036374 8.96 GGT1 GGT2
2 peptidyltransferase activity GO:0000048 8.62 GGT1 GGT2

Sources for Colloid Carcinoma of the Pancreas

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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