MCID: CLL009
MIFTS: 31

Colloid Carcinoma of the Pancreas

Categories: Cancer diseases, Endocrine diseases

Aliases & Classifications for Colloid Carcinoma of the Pancreas

MalaCards integrated aliases for Colloid Carcinoma of the Pancreas:

Name: Colloid Carcinoma of the Pancreas 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:7717
NCIt 51 C37214
UMLS 74 C1333081

Summaries for Colloid Carcinoma of the Pancreas

MalaCards based summary : Colloid Carcinoma of the Pancreas is related to pseudomyxoma peritonei and sigmoid neoplasm. An important gene associated with Colloid Carcinoma of the Pancreas is PSCA (Prostate Stem Cell Antigen), and among its related pathways/superpathways are Development EGFR signaling pathway and Integrated Breast Cancer Pathway. Affiliated tissues include pancreas, lung and liver, and related phenotypes are Decreased viability and Decreased viability

Related Diseases for Colloid Carcinoma of the Pancreas

Diseases related to Colloid Carcinoma of the Pancreas via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 70)
# Related Disease Score Top Affiliating Genes
1 pseudomyxoma peritonei 30.1 KRAS MUC1 MUC5AC
2 sigmoid neoplasm 10.3 HRAS KRAS
3 syringocystadenoma papilliferum 10.3 KRAS MUC1
4 paronychia 10.3 HRAS KRAS
5 familial colorectal cancer type x 10.3 BRCA2 SMAD4
6 mutyh-associated polyposis 10.3 KRAS SMAD4
7 schimmelpenning-feuerstein-mims syndrome 10.3 HRAS KRAS
8 bile duct cysts 10.3 HRAS KRAS
9 cryptogenic organizing pneumonia 10.3 MUC1 MUC5B
10 breast mucoepidermoid carcinoma 10.3 MUC1 MUC5AC
11 solid adenocarcinoma with mucin production 10.2 MUC1 MUC5AC
12 appendix disease 10.2 HRAS KRAS
13 lung adenoid cystic carcinoma 10.2 HRAS KRAS
14 nasal cavity adenocarcinoma 10.2 HRAS KRAS
15 apocrine adenoma 10.2 HRAS KRAS MUC1
16 bile duct cystadenocarcinoma 10.2 MUC1 MUC5AC
17 aggressive digital papillary adenocarcinoma 10.2 HRAS KRAS MUC1
18 duodenum cancer 10.2 HRAS KRAS MUC1
19 ampulla of vater cancer 10.2 HRAS KRAS MUC1
20 secondary hypertrophic osteoarthropathy 10.2 HRAS KRAS
21 carcinosarcoma 10.2 HRAS KRAS MUC1
22 bile duct mucoepidermoid carcinoma 10.2 MUC1 MUC5AC MUC5B
23 chronic ethmoiditis 10.2 MUC1 MUC5AC MUC5B
24 pancreas disease 10.2 HRAS KRAS SMAD4
25 ethmoid sinusitis 10.2 MUC1 MUC5AC MUC5B
26 colorectal cancer 1 10.1 MUC1 MUC5AC MUC5B
27 gastric cardia carcinoma 10.1 MUC1 MUC5AC SMAD4
28 anal gland adenocarcinoma 10.1 KRT19 MUC5AC
29 mucinous ovarian cystadenoma 10.1 MUC1 MUC5AC
30 ampulla of vater adenocarcinoma 10.1 BRCA2 MUC1
31 anus adenocarcinoma 10.1 KRT19 MUC5AC
32 immune system disease 10.1 MUC1 MUC5AC MUC5B
33 malignant struma ovarii 10.1 HRAS KRT19
34 filamentary keratitis 10.1 MUC1 MUC5AC
35 adenocarcinoma 10.1 HRAS KRAS MUC1 SMAD4
36 liver angiosarcoma 10.0 HRAS KRAS KRT19
37 ovarian cystadenocarcinoma 10.0 HRAS KRAS
38 respiratory system cancer 10.0 HRAS KRAS KRT19
39 pericardial mesothelioma 10.0 KRT19 MSLN MUC1
40 large intestine cancer 10.0 HRAS KRAS MUC1 SMAD4
41 pancreatic mucinous cystadenoma 10.0 HRAS MUC1 MUC5AC MUC5B
42 gastric adenocarcinoma 10.0 HRAS KRAS MUC1 SMAD4
43 respiratory system disease 9.9 HRAS KRAS MUC5AC MUC5B
44 gastrointestinal system cancer 9.9 HRAS KRAS KRT19 SMAD4
45 adenoid cystic carcinoma 9.9 HRAS KRAS KRT19 MUC1
46 cyclosporiasis 9.9 GGT1 GGT2
47 algoneurodystrophy 9.8 GGT1 GGT2
48 intrahepatic cholangiocarcinoma 9.8 KRAS KRT19 MUC1 MUC5AC
49 mucinous tubular and spindle renal cell carcinoma 9.8 KRT19 MUC1
50 squamous cell carcinoma 9.8 HRAS KRT19 MUC1 SMAD4

Graphical network of the top 20 diseases related to Colloid Carcinoma of the Pancreas:



Diseases related to Colloid Carcinoma of the Pancreas

Symptoms & Phenotypes for Colloid Carcinoma of the Pancreas

GenomeRNAi Phenotypes related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-2 9.47 HRAS KRAS MUC1
2 Decreased viability GR00106-A-0 9.47 KRAS
3 Decreased viability GR00221-A-1 9.47 HRAS KRAS
4 Decreased viability GR00221-A-2 9.47 HRAS KRAS
5 Decreased viability GR00221-A-3 9.47 HRAS
6 Decreased viability GR00301-A 9.47 KRAS
7 Decreased viability GR00381-A-1 9.47 KRAS
8 Decreased viability GR00402-S-2 9.47 HRAS KRAS MUC1

MGI Mouse Phenotypes related to Colloid Carcinoma of the Pancreas:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 10.03 BRCA2 HRAS KRAS KRT19 MUC5AC PHEX
2 immune system MP:0005387 10.02 BRCA2 GGT1 KRAS MUC5AC MUC5B PHEX
3 endocrine/exocrine gland MP:0005379 10.01 BRCA2 GGT1 HRAS KRAS KRT19 PHEX
4 integument MP:0010771 9.87 BRCA2 GGT1 HRAS KRAS KRT19 SFN
5 limbs/digits/tail MP:0005371 9.73 BRCA2 GGT1 KRAS PHEX SFN SMAD4
6 neoplasm MP:0002006 9.7 BRCA2 HRAS KRAS KRT19 PSCA SFN
7 normal MP:0002873 9.5 BRCA2 HRAS KRAS KRT19 MSLN PSCA
8 skeleton MP:0005390 9.23 BRCA2 GGT1 HRAS KRAS KRT19 PHEX

Drugs & Therapeutics for Colloid Carcinoma of the Pancreas

Search Clinical Trials , NIH Clinical Center for Colloid Carcinoma of the Pancreas

Genetic Tests for Colloid Carcinoma of the Pancreas

Anatomical Context for Colloid Carcinoma of the Pancreas

MalaCards organs/tissues related to Colloid Carcinoma of the Pancreas:

42
Pancreas, Lung, Liver, Breast, Ovary, Appendix

Publications for Colloid Carcinoma of the Pancreas

Articles related to Colloid Carcinoma of the Pancreas:

# Title Authors Year
1
Pseudomyxoma peritonei associated with colloid carcinoma of the pancreas. ( 2998918 )
1986

Variations for Colloid Carcinoma of the Pancreas

Expression for Colloid Carcinoma of the Pancreas

Search GEO for disease gene expression data for Colloid Carcinoma of the Pancreas.

Pathways for Colloid Carcinoma of the Pancreas

Pathways related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.11 HRAS KRAS MUC1 SMAD4
2 11.93 BRCA2 KRAS SMAD4
3
Show member pathways
11.86 MUC1 MUC5AC MUC5B
4 11.81 HRAS KRAS SMAD4
5
Show member pathways
11.79 HRAS KRAS SMAD4
6 11.77 HRAS KRAS SMAD4
7 11.64 HRAS KRAS SMAD4
8 11.6 HRAS KRAS SFN
9
Show member pathways
11.43 HRAS KRAS MUC1 MUC5AC MUC5B
10 11.33 HRAS KRAS SMAD4
11 10.94 GGT1 GGT2
12 10.91 GGT1 GGT2
13 10.9 HRAS KRAS
14 10.85 HRAS KRAS
15 10.73 HRAS KRAS
16 10.61 HRAS KRAS SMAD4
17 10.37 HRAS KRAS

GO Terms for Colloid Carcinoma of the Pancreas

Cellular components related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.85 GGT1 HRAS KRAS KRT19 MSLN MUC1
2 extracellular exosome GO:0070062 9.28 GGT1 GGT2 GGTLC3 KRT19 MUC1 MUC5AC
3 Golgi lumen GO:0005796 9.13 MUC1 MUC5AC MUC5B

Biological processes related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 female gonad development GO:0008585 9.54 BRCA2 SMAD4
2 regulation of long-term neuronal synaptic plasticity GO:0048169 9.52 HRAS KRAS
3 glutamate metabolic process GO:0006536 9.51 GGT1 GGT2
4 O-glycan processing GO:0016266 9.5 MUC1 MUC5AC MUC5B
5 zymogen activation GO:0031638 9.49 GGT1 GGT2
6 response to estradiol GO:0032355 9.48 GGT1 GGT2
7 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.46 BRCA2 MUC1
8 cysteine biosynthetic process GO:0019344 9.43 GGT1 GGT2
9 response to isolation stress GO:0035900 9.4 HRAS KRAS
10 regulation of immune system process GO:0002682 9.37 GGT1 GGT2
11 glutathione catabolic process GO:0006751 9.33 GGT1 GGT2 GGTLC3
12 peptide modification GO:0031179 9.26 GGT1 GGT2
13 leukotriene D4 biosynthetic process GO:1901750 9.13 GGT1 GGT2 GGTLC3
14 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.02 HRAS KRAS MUC1 MUC5AC MUC5B

Molecular functions related to Colloid Carcinoma of the Pancreas according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyltransferase activity GO:0000048 8.96 GGT1 GGT2
2 glutathione hydrolase activity GO:0036374 8.8 GGT1 GGT2 GGTLC3

Sources for Colloid Carcinoma of the Pancreas

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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