MCID: CLN011
MIFTS: 28

Colon Leiomyoma

Categories: Gastrointestinal diseases

Aliases & Classifications for Colon Leiomyoma

MalaCards integrated aliases for Colon Leiomyoma:

Name: Colon Leiomyoma 12 15 71
Colonic Leiomyoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10656
NCIt 50 C5492
UMLS 71 C1333092

Summaries for Colon Leiomyoma

MalaCards based summary : Colon Leiomyoma, also known as colonic leiomyoma, is related to leiomyoma and leiomyosarcoma. An important gene associated with Colon Leiomyoma is H3-4 (H3.4 Histone), and among its related pathways/superpathways are Developmental Biology and PI3K-Akt signaling pathway. Affiliated tissues include colon, and related phenotypes are behavior/neurological and mortality/aging

Related Diseases for Colon Leiomyoma

Diseases related to Colon Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 148)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 30.4 MED12 KIT FH CD34
2 leiomyosarcoma 30.2 MED12 KIT FH
3 smooth muscle tumor 29.7 MED12 KIT CD34 ANO1
4 adult brain stem glioma 10.4 H3-3B H3-3A
5 bone giant cell sarcoma 10.4 H3-3B H3-3A
6 malignant giant cell tumor 10.3 H3-3B H3-3A
7 telangiectatic osteogenic sarcoma 10.3 H3-3B H3-3A
8 spinal cord astrocytoma 10.3 H3-3B H3-3A
9 adult oligodendroglioma 10.3 H3-3B H3-3A
10 childhood oligodendroglioma 10.3 H3-3B H3-3A
11 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 10.3 KMT2A KIT
12 gastric leiomyosarcoma 10.3 KIT ANO1
13 small intestinal sarcoma 10.3 KIT ANO1
14 bizarre leiomyoma 10.3 MED12 FH
15 leiomyoma cutis 10.3 MED12 FH
16 childhood brain stem glioma 10.3 H3-3B H3-3A
17 dermis tumor 10.3 MED12 FH
18 mucinous stomach adenocarcinoma 10.3 KIT ANO1
19 childhood pilocytic astrocytoma 10.3 H3-3B H3-3A
20 juvenile pilocytic astrocytoma 10.2 H3-3B H3-3A
21 spinal cord sarcoma 10.2 KIT CD34
22 clear cell chondrosarcoma 10.2 H3-3B H3-3A
23 active peptic ulcer disease 10.2 KIT ANO1
24 bone giant cell tumor 10.2 H3-3B H3-3A CALCR
25 angiomyoma 10.2 KIT CD34
26 adult astrocytic tumour 10.2 H3-3B H3-3A
27 mucocele of appendix 10.2 KIT CD34
28 pineal region teratoma 10.2 SYP KIT
29 gallbladder leiomyosarcoma 10.2 KIT CD34
30 benign fibrous mesothelioma 10.2 KIT CD34
31 laryngeal small cell carcinoma 10.2 SYP KIT
32 retroperitoneal hemangiopericytoma 10.2 KIT CD34
33 breast leiomyosarcoma 10.2 KIT CD34
34 peritoneal benign neoplasm 10.2 MED12 CD34
35 leiomyomatosis 10.2 MED12 KIT FH
36 liver fibroma 10.2 KIT CD34
37 heart sarcoma 10.2 KIT CD34
38 skin sarcoma 10.2 KIT CD34
39 intravenous leiomyomatosis 10.2 MED12 CD34
40 vaginal endometrial stromal sarcoma 10.2 KIT CD34
41 chondroblastic osteosarcoma 10.2 H3-3B H3-3A
42 dartoic leiomyoma 10.2 FH CD34
43 chondroblastoma 10.2 H3-3B H3-3A ANO1
44 gastric leiomyoma 10.2 KIT FH ANO1
45 nasal cavity benign neoplasm 10.2 KIT CD34
46 parasagittal meningioma 10.2 CD34 ANO1
47 endometrial small cell carcinoma 10.2 SYP KIT
48 vagina sarcoma 10.2 KIT CD34
49 central nervous system leukemia 10.2 KMT2A CD34
50 benign breast phyllodes tumor 10.1 KIT CD34

Graphical network of the top 20 diseases related to Colon Leiomyoma:



Diseases related to Colon Leiomyoma

Symptoms & Phenotypes for Colon Leiomyoma

MGI Mouse Phenotypes related to Colon Leiomyoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10 AKT3 ANO1 CALCR DIS3 FOXO1 H3-3B
2 mortality/aging MP:0010768 9.97 AKT3 ANO1 CALCR DIS3 FH FOXA1
3 neoplasm MP:0002006 9.43 AKT3 CD34 FOXA1 FOXO1 KIT KMT2A
4 normal MP:0002873 9.28 AKT3 CALCR FOXO1 H3-3B KIT KMT2A

Drugs & Therapeutics for Colon Leiomyoma

Search Clinical Trials , NIH Clinical Center for Colon Leiomyoma

Genetic Tests for Colon Leiomyoma

Anatomical Context for Colon Leiomyoma

MalaCards organs/tissues related to Colon Leiomyoma:

40
Colon

Publications for Colon Leiomyoma

Articles related to Colon Leiomyoma:

(show all 24)
# Title Authors PMID Year
1
Colonic Mucosubmucosal Elongated Polyp in the Sigmoid Colon on Surveillance Colonoscopy. 61
31616775 2019
2
Total laparoscopic surgery for treatment of leiomyoma of the transverse colon in a patient with an abdominal mesh: A case report. 61
31610453 2019
3
Two Cases of Leiomyoma in the Colon Masquerading as Other Types of Colonic Pedunculated Polyps. 61
29854494 2018
4
Cecal Leiomyoma: Can We Attempt Endoscopic Resection? 61
28058080 2016
5
Giant extraluminal leiomyoma of the colon: rare cause of symptomatic pelvic mass. 61
26011198 2015
6
Endoscopic Removal of Pedunculated Leiomyoma of the Sigmoid Colon. 61
26288610 2014
7
[Gastric cancer arising from gastric polyps in gardner syndrome - a case report]. 61
25731489 2014
8
A case of endoscopic resection of a colonic semipedunculated leiomyoma. 61
21980593 2011
9
Obscure-occult bleeding: resolution of unexplained chronic sideropenic anaemia by colonoscopic removal of a colonic leiomyoma. 61
22714624 2011
10
Colonic leiomyoma with huge ulceration. 61
18227569 2007
11
Endoscopic removal of pedunculated leiomyoma of the sigmoid colon (case report and literature review of dignostic and treatment options). 61
16989154 2006
12
[A case of pedunculated leiomyoma found during colonoscopic examination for anal bleeding]. 61
14978371 2004
13
Endoscopic resection of a large colonic leiomyoma. 61
11926585 2002
14
Colonic leiomyoma in a 12-year-old patient with tuberous sclerosis: a case report and brief review. 61
11396824 2001
15
Endosonographic probe-guided endoscopic removal of colonic pedunculated leiomyoma. 61
11190001 2000
16
Gastrointestinal tumors observed in nonhuman primates at the German primate center. 61
10203013 1998
17
Endoscopic removal of leiomyoma of the colon. 61
11847381 1997
18
[Hemoperitoneum caused by leiomyoma of the colon]. 61
9082239 1996
19
Gastrointestinal involvement in tuberous sclerosis. Two case reports. 61
7930433 1994
20
Endoscopic removal of colonic leiomyoma. 61
1500663 1992
21
Giant cystic leiomyoma of the sigmoid colon. 61
2009498 1991
22
Colonic leiomyoma--an unusual cause of gastrointestinal hemorrhage in childhood. Report of a case. 61
2351006 1990
23
Colonoscopic removal of a colonic leiomyoma: report of a case. 61
499727 1979
24
[An unusual case of transverse colonic leiomyoma revealed as malignant]. 61
5385929 1969

Variations for Colon Leiomyoma

Expression for Colon Leiomyoma

Search GEO for disease gene expression data for Colon Leiomyoma.

Pathways for Colon Leiomyoma

GO Terms for Colon Leiomyoma

Cellular components related to Colon Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleoplasm GO:0005654 9.65 NOTCH4 MED12 KMT2A H3-4 H3-3B H3-3A
2 nucleosome GO:0000786 9.33 H3-4 H3-3B H3-3A
3 Barr body GO:0001740 8.62 H3-3B H3-3A

Biological processes related to Colon Leiomyoma according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 nucleosome assembly GO:0006334 9.65 H3-4 H3-3B H3-3A
2 Notch signaling pathway GO:0007219 9.63 NOTCH4 IL2RA FOXA1
3 male gonad development GO:0008584 9.61 KIT H3-3B H3-3A
4 spermatid development GO:0007286 9.58 KIT H3-3B H3-3A
5 regulation of megakaryocyte differentiation GO:0045652 9.54 KMT2A H3-3B H3-3A
6 muscle cell differentiation GO:0042692 9.51 H3-3B H3-3A
7 hemopoiesis GO:0030097 9.5 NOTCH4 KIT CD34
8 embryonic hemopoiesis GO:0035162 9.49 KMT2A KIT
9 pericentric heterochromatin assembly GO:0031508 9.26 H3-3B H3-3A
10 regulation of centromere complex assembly GO:0090230 9.16 H3-3B H3-3A
11 negative regulation of chromosome condensation GO:1902340 8.96 H3-3B H3-3A
12 telomeric heterochromatin assembly GO:0031509 8.62 H3-3B H3-3A

Sources for Colon Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....