MCID: CLN011
MIFTS: 23

Colon Leiomyoma

Categories: Gastrointestinal diseases

Aliases & Classifications for Colon Leiomyoma

MalaCards integrated aliases for Colon Leiomyoma:

Name: Colon Leiomyoma 12 15 71
Colonic Leiomyoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10656
NCIt 49 C5492
UMLS 71 C1333092

Summaries for Colon Leiomyoma

MalaCards based summary : Colon Leiomyoma, also known as colonic leiomyoma, is related to leiomyoma and gastric leiomyoma. An important gene associated with Colon Leiomyoma is FGG (Fibrinogen Gamma Chain), and among its related pathways/superpathways are Collagen chain trimerization and Development Angiotensin activation of ERK. Affiliated tissues include colon.

Related Diseases for Colon Leiomyoma

Diseases related to Colon Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 leiomyoma 10.4
2 gastric leiomyoma 9.8
3 tuberous sclerosis 9.8
4 leiomyosarcoma 9.8
5 smooth muscle tumor 9.8
6 dysfibrinogenemia, congenital 9.2 FGG FGB FGA
7 inherited blood coagulation disease 9.2 FGG FGB FGA
8 afibrinogenemia, congenital 9.1 FGG FGB FGA
9 thrombophilia 9.0 FGG FGB FGA
10 thrombosis 8.9 FGG FGB FGA

Graphical network of the top 20 diseases related to Colon Leiomyoma:



Diseases related to Colon Leiomyoma

Symptoms & Phenotypes for Colon Leiomyoma

Drugs & Therapeutics for Colon Leiomyoma

Search Clinical Trials , NIH Clinical Center for Colon Leiomyoma

Genetic Tests for Colon Leiomyoma

Anatomical Context for Colon Leiomyoma

MalaCards organs/tissues related to Colon Leiomyoma:

40
Colon

Publications for Colon Leiomyoma

Articles related to Colon Leiomyoma:

(show all 24)
# Title Authors PMID Year
1
Colonic Mucosubmucosal Elongated Polyp in the Sigmoid Colon on Surveillance Colonoscopy. 61
31616775 2019
2
Total laparoscopic surgery for treatment of leiomyoma of the transverse colon in a patient with an abdominal mesh: A case report. 61
31610453 2019
3
Two Cases of Leiomyoma in the Colon Masquerading as Other Types of Colonic Pedunculated Polyps. 61
29854494 2018
4
Cecal Leiomyoma: Can We Attempt Endoscopic Resection? 61
28058080 2016
5
Giant extraluminal leiomyoma of the colon: rare cause of symptomatic pelvic mass. 61
26011198 2015
6
Endoscopic Removal of Pedunculated Leiomyoma of the Sigmoid Colon. 61
26288610 2014
7
[Gastric cancer arising from gastric polyps in gardner syndrome - a case report]. 61
25731489 2014
8
A case of endoscopic resection of a colonic semipedunculated leiomyoma. 61
21980593 2011
9
Obscure-occult bleeding: resolution of unexplained chronic sideropenic anaemia by colonoscopic removal of a colonic leiomyoma. 61
22714624 2011
10
Colonic leiomyoma with huge ulceration. 61
18227569 2007
11
Endoscopic removal of pedunculated leiomyoma of the sigmoid colon (case report and literature review of dignostic and treatment options). 61
16989154 2006
12
[A case of pedunculated leiomyoma found during colonoscopic examination for anal bleeding]. 61
14978371 2004
13
Endoscopic resection of a large colonic leiomyoma. 61
11926585 2002
14
Colonic leiomyoma in a 12-year-old patient with tuberous sclerosis: a case report and brief review. 61
11396824 2001
15
Endosonographic probe-guided endoscopic removal of colonic pedunculated leiomyoma. 61
11190001 2000
16
Gastrointestinal tumors observed in nonhuman primates at the German primate center. 61
10203013 1998
17
Endoscopic removal of leiomyoma of the colon. 61
11847381 1997
18
[Hemoperitoneum caused by leiomyoma of the colon]. 61
9082239 1996
19
Gastrointestinal involvement in tuberous sclerosis. Two case reports. 61
7930433 1994
20
Endoscopic removal of colonic leiomyoma. 61
1500663 1992
21
Giant cystic leiomyoma of the sigmoid colon. 61
2009498 1991
22
Colonic leiomyoma--an unusual cause of gastrointestinal hemorrhage in childhood. Report of a case. 61
2351006 1990
23
Colonoscopic removal of a colonic leiomyoma: report of a case. 61
499727 1979
24
[An unusual case of transverse colonic leiomyoma revealed as malignant]. 61
5385929 1969

Variations for Colon Leiomyoma

Expression for Colon Leiomyoma

Search GEO for disease gene expression data for Colon Leiomyoma.

Pathways for Colon Leiomyoma

Pathways related to Colon Leiomyoma according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.41 FGG FGB FGA
2
Show member pathways
12.41 FGG FGB FGA
3
Show member pathways
12.32 FGG FGB FGA
4
Show member pathways
11.94 FGG FGB FGA
5
Show member pathways
11.81 FGG FGB FGA
6
Show member pathways
11.77 FGG FGB FGA
7 11.71 FGG FGB FGA
8
Show member pathways
11.63 FGG FGB FGA
9 11.53 FGG FGB FGA
10
Show member pathways
11.32 FGG FGB FGA
11 10.84 FGG FGB FGA
12 10.49 FGG FGB FGA

GO Terms for Colon Leiomyoma

Cellular components related to Colon Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.73 H3-4 FGG FGB FGA
2 cell surface GO:0009986 9.58 FGG FGB FGA
3 external side of plasma membrane GO:0009897 9.54 FGG FGB FGA
4 collagen-containing extracellular matrix GO:0062023 9.5 FGG FGB FGA
5 extracellular vesicle GO:1903561 9.48 FGB FGA
6 cell cortex GO:0005938 9.46 FGB FGA
7 blood microparticle GO:0072562 9.43 FGG FGB FGA
8 platelet alpha granule lumen GO:0031093 9.33 FGG FGB FGA
9 platelet alpha granule GO:0031091 9.13 FGG FGB FGA
10 fibrinogen complex GO:0005577 8.8 FGG FGB FGA

Biological processes related to Colon Leiomyoma according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.79 FGG FGB FGA
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.79 FGG FGB FGA
3 blood coagulation GO:0007596 9.78 FGG FGB FGA
4 platelet degranulation GO:0002576 9.77 FGG FGB FGA
5 platelet activation GO:0030168 9.76 FGG FGB FGA
6 cell-matrix adhesion GO:0007160 9.75 FGG FGB FGA
7 response to calcium ion GO:0051592 9.74 FGG FGB FGA
8 hemostasis GO:0007599 9.73 FGG FGB FGA
9 positive regulation of protein secretion GO:0050714 9.72 FGG FGB FGA
10 platelet aggregation GO:0070527 9.71 FGG FGB FGA
11 toll-like receptor signaling pathway GO:0002224 9.7 FGG FGB FGA
12 positive regulation of substrate adhesion-dependent cell spreading GO:1900026 9.69 FGG FGB FGA
13 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 9.67 FGG FGB FGA
14 negative regulation of endothelial cell apoptotic process GO:2000352 9.65 FGG FGB FGA
15 positive regulation of vasoconstriction GO:0045907 9.63 FGG FGB FGA
16 cellular response to interleukin-1 GO:0071347 9.62 FGG FGB
17 positive regulation of exocytosis GO:0045921 9.61 FGG FGB FGA
18 induction of bacterial agglutination GO:0043152 9.59 FGB FGA
19 cellular protein-containing complex assembly GO:0034622 9.58 FGG FGB FGA
20 fibrinolysis GO:0042730 9.54 FGG FGB FGA
21 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.5 FGG FGB FGA
22 protein polymerization GO:0051258 9.43 FGG FGB FGA
23 plasminogen activation GO:0031639 9.33 FGG FGB FGA
24 positive regulation of peptide hormone secretion GO:0090277 9.13 FGG FGB FGA
25 blood coagulation, fibrin clot formation GO:0072378 8.8 FGG FGB FGA

Molecular functions related to Colon Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.43 FGG FGB FGA
2 structural molecule activity GO:0005198 9.33 FGG FGB FGA
3 extracellular matrix structural constituent GO:0005201 9.13 FGG FGB FGA
4 cell adhesion molecule binding GO:0050839 8.8 FGG FGB FGA

Sources for Colon Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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