MCID: CLN012
MIFTS: 23

Colon Leiomyosarcoma

Categories: Cancer diseases, Gastrointestinal diseases, Muscle diseases

Aliases & Classifications for Colon Leiomyosarcoma

MalaCards integrated aliases for Colon Leiomyosarcoma:

Name: Colon Leiomyosarcoma 12 15 72
Colonic Leiomyosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5259
NCIt 50 C5494
UMLS 72 C1333093

Summaries for Colon Leiomyosarcoma

Disease Ontology : 12 A leiomyosarcoma and sarcoma of colon that is located in the colon.

MalaCards based summary : Colon Leiomyosarcoma, also known as colonic leiomyosarcoma, is related to leiomyosarcoma and leiomyoma. An important gene associated with Colon Leiomyosarcoma is KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include colon and colon, and related phenotype is integument.

Related Diseases for Colon Leiomyosarcoma

Diseases related to Colon Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 47)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 10.5
2 leiomyoma 10.1 KIT CD34
3 lung leiomyosarcoma 10.0 KIT CD34
4 gallbladder leiomyoma 10.0 KIT CD34
5 deep leiomyoma 10.0 KIT CD34
6 extracutaneous mastocytoma 10.0 KIT CD34
7 prostate leiomyosarcoma 10.0 KIT CD34
8 gallbladder sarcoma 10.0 KIT CD34
9 conventional fibrosarcoma 10.0 KIT CD34
10 plexiform schwannoma 10.0 KIT CD34
11 diffuse peritoneal leiomyomatosis 10.0 KIT CD34
12 peritoneal benign neoplasm 10.0 KIT CD34
13 breast angiosarcoma 10.0 KIT CD34
14 senile angioma 10.0 KIT CD34
15 angiomyoma 10.0 KIT CD34
16 spindle cell liposarcoma 10.0 KIT CD34
17 mesenchymal cell neoplasm 10.0 KIT CD34
18 benign perivascular tumor 10.0 KIT CD34
19 cardiovascular organ benign neoplasm 9.9 KIT CD34
20 muscle cancer 9.9 KIT CD34
21 vascular cancer 9.9 KIT CD34
22 neurofibroma 9.9 KIT CD34
23 connective tissue cancer 9.9 KIT CD34
24 leukocyte disease 9.9 KIT CD34
25 dermatofibrosarcoma protuberans 9.9 KIT CD34
26 gastrointestinal system cancer 9.8 KIT CD34
27 meckel diverticulum 9.8
28 lymphoma 9.8
29 colitis 9.8
30 adenocarcinoma 9.8
31 adenoma 9.8
32 ulcerative colitis 9.8
33 acute leukemia 9.8 KIT CD34
34 bone marrow cancer 9.8 KIT CD34
35 myelofibrosis 9.8 KIT CD34
36 gastric leiomyosarcoma 9.7 KIT ANO1
37 muscular disease 9.7 KIT CD34
38 gastric cardia carcinoma 9.7 KIT ANO1
39 ovarian brenner tumor 9.7 KIT ANO1
40 myeloma, multiple 9.7 KIT CD34
41 leukemia, acute myeloid 9.7 KIT CD34
42 leukemia, chronic myeloid 9.6 KIT CD34
43 hematologic cancer 9.4 KIT CD34
44 liver leiomyoma 9.3 KIT CD34 ANO1
45 small intestinal sarcoma 9.3 KIT CD34 ANO1
46 small intestine leiomyosarcoma 9.3 KIT CD34 ANO1
47 gastrointestinal stromal tumor 9.3 KIT CD34 ANO1

Graphical network of the top 20 diseases related to Colon Leiomyosarcoma:



Diseases related to Colon Leiomyosarcoma

Symptoms & Phenotypes for Colon Leiomyosarcoma

MGI Mouse Phenotypes related to Colon Leiomyosarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.8 ANO1 CD34 KIT

Drugs & Therapeutics for Colon Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Colon Leiomyosarcoma

Genetic Tests for Colon Leiomyosarcoma

Anatomical Context for Colon Leiomyosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Colon Leiomyosarcoma:

19
Colon

MalaCards organs/tissues related to Colon Leiomyosarcoma:

41
Colon

Publications for Colon Leiomyosarcoma

Articles related to Colon Leiomyosarcoma:

# Title Authors PMID Year
1
Case Report: Collision Tumour of Colon Leiomyosarcoma and Adenocarcinoma. 38
27504346 2016
2
A Rare Case of Colonic Leiomyosarcoma in Association with Ulcerative Colitis. 38
27725539 2016
3
Endoscopic resection of a large colonic leiomyosarcoma. 38
23012010 2012
4
Caffeine-assisted chemotherapy for colonic leiomyosarcoma. 38
10201501 1999
5
Ultrastructure of hepatic metastases from a colon leiomyosarcoma. 38
9505209 1997
6
Leiomyosarcoma of the colon presenting as acute suppurative peritonitis. 38
9086551 1997
7
Operative laparoscopy followed by colpotomy for resecting a colonic leiomyosarcoma. A case report. 38
1840072 1991
8
Diverticulosis and colonic leiomyosarcoma in an aged rhesus macaque. 38
2763427 1989
9
An unusual case of colonic leiomyosarcoma presenting with fever--significant uptake of radioactivity of gallium-67 in the tumor. 38
6519418 1984
10
Leiomyosarcoma of the colon. 38
663703 1978

Variations for Colon Leiomyosarcoma

Expression for Colon Leiomyosarcoma

Search GEO for disease gene expression data for Colon Leiomyosarcoma.

Pathways for Colon Leiomyosarcoma

GO Terms for Colon Leiomyosarcoma

Cellular components related to Colon Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.96 KIT CD34
2 apical plasma membrane GO:0016324 8.62 CD34 ANO1

Biological processes related to Colon Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hemopoiesis GO:0030097 8.62 KIT CD34

Sources for Colon Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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