MCID: CLN005
MIFTS: 30

Colon Lymphoma

Categories: Cancer diseases, Immune diseases, Gastrointestinal diseases

Aliases & Classifications for Colon Lymphoma

MalaCards integrated aliases for Colon Lymphoma:

Name: Colon Lymphoma 12 15
Lymphoma of Colon 73
Colonic Lymphoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1523
NCIt 50 C4793
SNOMED-CT 68 133751000119102
UMLS 73 C0519037

Summaries for Colon Lymphoma

MalaCards based summary : Colon Lymphoma, also known as lymphoma of colon, is related to lymphoma and bone lymphoma. An important gene associated with Colon Lymphoma is IRF4 (Interferon Regulatory Factor 4), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and NF-kappaB Signaling. Affiliated tissues include colon, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Related Diseases for Colon Lymphoma

Diseases related to Colon Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 lymphoma 28.5 ALK BCL6 TNFRSF8
2 bone lymphoma 10.7 BCL6 CD22
3 primary mediastinal large b-cell lymphoma 10.7 BCL6 IRF4
4 primary effusion lymphoma 10.6 BCL6 IRF4
5 intravascular large b-cell lymphoma 10.6 BCL6 CD5
6 composite lymphoma 10.5 BCL6 CD5
7 richter's syndrome 10.5 CD5 IRF4
8 heart lymphoma 10.5 BCL6 PTPRC
9 nodular lymphocyte predominant hodgkin lymphoma 10.5 BCL6 PTPRC
10 testicular lymphoma 10.5 BCL6 PTPRC
11 posterior scleritis 10.4 CD19 CD22
12 primary cutaneous diffuse large b-cell lymphoma, leg type 10.4 CDKN2A IRF4
13 t-cell/histiocyte rich large b cell lymphoma 10.4 BCL6 TNFRSF8
14 bladder lymphoma 10.3 CD19 CD5
15 cd45 deficiency 10.3 CD5 PTPRC
16 lateral medullary syndrome 10.3 CD19 CD22
17 b cell prolymphocytic leukemia 10.3 CD19 CD5
18 marginal zone b-cell lymphoma 10.3 BCL6 CD5 IRF4
19 plasma protein metabolism disease 10.3 CD19 CD5
20 lymphoma, mucosa-associated lymphoid type 10.3 BCL6 CD5 IRF4
21 splenic marginal zone lymphoma 10.2 BCL6 CD5
22 conventional fibrosarcoma 10.2 PTPRC TNFRSF8
23 primary central nervous system lymphoma 10.2 BCL6 CDKN2A
24 testicular infarct 10.2 PTPRC TNFRSF8
25 reticulum cell sarcoma 10.2 PTPRC TNFRSF8
26 lymphosarcoma 10.2 BCL6 CD22 PTPRC
27 mediastinal malignant lymphoma 10.2 BCL6 TNFRSF8
28 gamma heavy chain disease 10.2 CD19 PTPRC
29 breast lymphoma 10.2 ALK BCL6 CD5
30 primary cutaneous anaplastic large cell lymphoma 10.1 ALK IRF4 PTPRC
31 necrotizing sialometaplasia 10.1 CD5 CDKN2A
32 reticulohistiocytic granuloma 10.1 PTPRC TNFRSF8
33 malignant fibroxanthoma 10.1 ALK PTPRC
34 plasma cell neoplasm 10.1 CD19 PTPRC
35 lymphoblastic lymphoma 10.1 BCL6 CD5 PTPRC
36 anterior scleritis 10.1 CD19 CD22 CD5
37 ecthyma 10.0 ALK TNFRSF8
38 mucinous adenocarcinoma 10.0 ALK CDKN2A
39 adult lymphoma 9.9 ALK CD5 TNFRSF8
40 mature b-cell neoplasm 9.9 BCL6 CD19 PTPRC
41 pityriasis lichenoides et varioliformis acuta 9.9 CD7 TNFRSF8
42 immune system organ benign neoplasm 9.9 CD5 PTPRC TNFRSF8
43 central nervous system lymphoma 9.9 BCL6 CDKN2A
44 thymus lipoma 9.9 CD5 PTPRC TNFRSF8
45 pityriasis lichenoides 9.8 CD7 TNFRSF8
46 hodgkin's lymphoma, lymphocytic depletion 9.8 ALK PTPRC TNFRSF8
47 rhabdomyosarcoma 9.8 ALK MSH6 PTPRC
48 anaplastic large cell lymphoma 9.8 ALK PTPRC TNFRSF8
49 plasmablastic lymphoma 9.8 BCL6 CDKN2A PTPRC
50 prolymphocytic leukemia 9.8 CD19 CD5

Graphical network of the top 20 diseases related to Colon Lymphoma:



Diseases related to Colon Lymphoma

Symptoms & Phenotypes for Colon Lymphoma

GenomeRNAi Phenotypes related to Colon Lymphoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.02 CD5 CD7 PTPRC BCL6 CD22

MGI Mouse Phenotypes related to Colon Lymphoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.85 BCL6 CD19 CD22 CD5 CD7 CDKN2A
2 endocrine/exocrine gland MP:0005379 9.73 ALK BCL6 CD7 CDKN2A PTPRC TNFRSF8
3 immune system MP:0005387 9.65 BCL6 CD19 CD22 CD5 CD7 CDKN2A
4 neoplasm MP:0002006 9.1 IRF4 MSH6 PTPRC ALK CD19 CDKN2A

Drugs & Therapeutics for Colon Lymphoma

Search Clinical Trials , NIH Clinical Center for Colon Lymphoma

Genetic Tests for Colon Lymphoma

Anatomical Context for Colon Lymphoma

MalaCards organs/tissues related to Colon Lymphoma:

41
Colon

Publications for Colon Lymphoma

Articles related to Colon Lymphoma:

# Title Authors Year
1
The management of primary small bowel and colon lymphoma--a review. ( 21912877 )
2012
2
Colon lymphoma causing intussusception. ( 22449682 )
2012
3
Primary colon lymphoma in Korea: a KASID (Korean Association for the Study of Intestinal Diseases) Study. ( 16416168 )
2005
4
Unexpected detection of colon lymphoma on a Tc-99m-labeled red blood cell abdominal scan. ( 11129152 )
2000
5
Colonic lymphoma producing alpha-chain disease protein. ( 6804299 )
1982

Variations for Colon Lymphoma

Expression for Colon Lymphoma

Search GEO for disease gene expression data for Colon Lymphoma.

Pathways for Colon Lymphoma

GO Terms for Colon Lymphoma

Biological processes related to Colon Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 9.33 ALK BCL6 TNFRSF8
2 T cell activation GO:0042110 9.26 CD7 IRF4
3 positive regulation of B cell proliferation GO:0030890 8.96 BCL6 PTPRC
4 negative regulation of cell-matrix adhesion GO:0001953 8.62 BCL6 CDKN2A

Sources for Colon Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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