MCID: CLN005
MIFTS: 37

Colon Lymphoma

Categories: Blood diseases, Cancer diseases, Gastrointestinal diseases, Immune diseases

Aliases & Classifications for Colon Lymphoma

MalaCards integrated aliases for Colon Lymphoma:

Name: Colon Lymphoma 12 15
Lymphoma of Colon 73
Colonic Lymphoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1523
NCIt 50 C4793
UMLS 73 C0519037

Summaries for Colon Lymphoma

MalaCards based summary : Colon Lymphoma, also known as lymphoma of colon, is related to bone lymphoma and primary mediastinal large b-cell lymphoma. An important gene associated with Colon Lymphoma is IRF4 (Interferon Regulatory Factor 4), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and NF-kappaB Signaling. Affiliated tissues include colon, b cells and bone, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Related Diseases for Colon Lymphoma

Diseases related to Colon Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 85)
# Related Disease Score Top Affiliating Genes
1 bone lymphoma 10.2 BCL6 CD22
2 primary mediastinal large b-cell lymphoma 10.2 BCL6 IRF4
3 primary effusion lymphoma 10.2 BCL6 IRF4
4 intravascular large b-cell lymphoma 10.2 BCL6 CD5
5 mediastinal cancer 10.2 CD5 CD79A
6 central nervous system hematologic cancer 10.2 BCL6 IRF4
7 heart lymphoma 10.2 BCL6 PTPRC
8 composite lymphoma 10.2 BCL6 CD5
9 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.2 BCL6 PTPRC
10 testicular lymphoma 10.2 BCL6 PTPRC
11 relapsed/refractory diffuse large b-cell lymphoma 10.2 CD19 IRF4
12 selective igg deficiency disease 10.1 CD19 CD79A
13 posterior scleritis 10.1 CD19 CD22
14 richter's syndrome 10.1 CD5 IRF4
15 congenital hypogammaglobulinemia 10.1 CD19 CD79A
16 primary cutaneous diffuse large b-cell lymphoma, leg type 10.1 CDKN2A IRF4
17 solitary osseous plasmacytoma 10.1 CD19 CD79A
18 t-cell/histiocyte rich large b cell lymphoma 10.1 BCL6 TNFRSF8
19 cd45 deficiency 10.1 CD5 PTPRC
20 lateral medullary syndrome 10.1 CD19 CD22
21 breast lymphoma 10.1 BCL6 CD5 CD79A
22 plasmacytoma 10.1 CD79A IRF4 PTPRC
23 b cell prolymphocytic leukemia 10.1 CD19 CD5
24 conventional fibrosarcoma 10.1 PTPRC TNFRSF8
25 waldenstroem's macroglobulinemia 10.1 CD19 CD5
26 testicular infarct 10.1 PTPRC TNFRSF8
27 plasma protein metabolism disease 10.1 CD19 CD5
28 gamma heavy chain disease 10.1 CD19 PTPRC
29 reticulum cell sarcoma 10.1 PTPRC TNFRSF8
30 lymphoepithelioma-like thymic carcinoma 10.1 CD5 CDKN2A
31 primary cutaneous anaplastic large cell lymphoma 10.0 ALK IRF4 PTPRC
32 lymphoblastic lymphoma 10.0 BCL6 CD5 PTPRC
33 autoimmune lymphoproliferative syndrome, type v 10.0 ALK BCL6 CD5
34 reticulohistiocytic granuloma 10.0 PTPRC TNFRSF8
35 splenic marginal zone lymphoma 10.0 BCL6 CD5
36 mediastinal malignant lymphoma 10.0 BCL6 CD79A TNFRSF8
37 anterior scleritis 10.0 CD19 CD22 CD5
38 bladder lymphoma 10.0 CD19 CD5 CD79A
39 lymphoma 10.0
40 necrotizing sialometaplasia 10.0 CD5 CDKN2A
41 cryoglobulinemia 10.0 CD5 CD79A
42 plasma cell neoplasm 10.0 CD19 CD79A PTPRC
43 marginal zone b-cell lymphoma 10.0 BCL6 CD5 CD79A IRF4
44 ecthyma 10.0 ALK TNFRSF8
45 thymus lipoma 10.0 CD5 PTPRC TNFRSF8
46 immune system organ benign neoplasm 10.0 CD5 PTPRC TNFRSF8
47 adult lymphoma 10.0 ALK CD5 TNFRSF8
48 pityriasis lichenoides 10.0 CD7 TNFRSF8
49 pityriasis lichenoides et varioliformis acuta 10.0 CD7 TNFRSF8
50 transient hypogammaglobulinemia of infancy 10.0 ALK CD19

Graphical network of the top 20 diseases related to Colon Lymphoma:



Diseases related to Colon Lymphoma

Symptoms & Phenotypes for Colon Lymphoma

GenomeRNAi Phenotypes related to Colon Lymphoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 BCL6 CD22 CD5 CD7 CD79A PTPRC

MGI Mouse Phenotypes related to Colon Lymphoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 BCL6 CD19 CD22 CD5 CD7 CD79A
2 cellular MP:0005384 9.86 BCL6 CD19 CD22 CD79A CDKN2A IRF4
3 immune system MP:0005387 9.7 BCL6 CD19 CD22 CD5 CD7 CD79A
4 neoplasm MP:0002006 9.17 ALK CD19 CD79A CDKN2A IRF4 MSH6

Drugs & Therapeutics for Colon Lymphoma

Search Clinical Trials , NIH Clinical Center for Colon Lymphoma

Genetic Tests for Colon Lymphoma

Anatomical Context for Colon Lymphoma

MalaCards organs/tissues related to Colon Lymphoma:

41
Colon, B Cells, Bone, Heart, T Cells, Thymus, Small Intestine

Publications for Colon Lymphoma

Articles related to Colon Lymphoma:

(show all 11)
# Title Authors Year
1
The management of primary small bowel and colon lymphoma--a review. ( 21912877 )
2012
2
Colon lymphoma causing intussusception. ( 22449682 )
2012
3
Sudden onset of renal failure requiring dialysis associated with large B-cell lymphoma of colon. ( 24475418 )
2012
4
Aggressive Burkitt-like lymphoma of colon in a patient with prior celiac disease. ( 17940628 )
2006
5
Primary colon lymphoma in Korea: a KASID (Korean Association for the Study of Intestinal Diseases) Study. ( 16416168 )
2005
6
Mantle-cell lymphoma of colon. ( 15729249 )
2005
7
Unusual abdominal tumors: case 3. Multiple lymphomatous polyposis in lymphoma of colon. ( 12610202 )
2003
8
Unexpected detection of colon lymphoma on a Tc-99m-labeled red blood cell abdominal scan. ( 11129152 )
2000
9
Successful nonsurgical treatment of primary mucosa-associated lymphoid tissue lymphoma of colon presenting with multiple polypoid lesions. ( 11007252 )
2000
10
Primary low grade B-cell lymphoma of colon mimicking inflammatory bowel disease: a case report. ( 9294917 )
1997
11
Hodgkin's lymphoma of colon: an unusual cause of isolated splenic vein obstruction. ( 8206544 )
1994

Variations for Colon Lymphoma

Expression for Colon Lymphoma

Search GEO for disease gene expression data for Colon Lymphoma.

Pathways for Colon Lymphoma

GO Terms for Colon Lymphoma

Cellular components related to Colon Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.92 CD19 CD5 CD79A PTPRC

Biological processes related to Colon Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of immune response GO:0050776 9.58 BCL6 CD19 CD22
2 positive regulation of B cell proliferation GO:0030890 9.43 BCL6 PTPRC
3 B cell receptor signaling pathway GO:0050853 9.43 CD19 CD79A PTPRC
4 B cell proliferation GO:0042100 9.37 CD79A PTPRC
5 negative regulation of cell-matrix adhesion GO:0001953 9.32 BCL6 CDKN2A
6 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.16 IRF4 PTPRC
7 B cell differentiation GO:0030183 9.13 BCL6 CD79A PTPRC
8 T cell activation GO:0042110 8.8 CD7 IRF4 PTPRC

Molecular functions related to Colon Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.92 ALK CD5 CD79A TNFRSF8

Sources for Colon Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....