MCID: CLN005
MIFTS: 33

Colon Lymphoma

Categories: Blood diseases, Cancer diseases, Gastrointestinal diseases, Immune diseases

Aliases & Classifications for Colon Lymphoma

MalaCards integrated aliases for Colon Lymphoma:

Name: Colon Lymphoma 12 15
Lymphoma of Colon 74
Colonic Lymphoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1523
NCIt 51 C4793
UMLS 74 C0519037

Summaries for Colon Lymphoma

MalaCards based summary : Colon Lymphoma, also known as lymphoma of colon, is related to mantle cell lymphoma and primary mediastinal large b-cell lymphoma. An important gene associated with Colon Lymphoma is RFWD3 (Ring Finger And WD Repeat Domain 3), and among its related pathways/superpathways are Immune response Fc epsilon RI pathway and NF-kappaB Signaling. Affiliated tissues include colon, b cells and thyroid, and related phenotypes are Reduced mammosphere formation and cellular

Related Diseases for Colon Lymphoma

Diseases related to Colon Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 82)
# Related Disease Score Top Affiliating Genes
1 mantle cell lymphoma 28.6 BCL6 CD19 CD5 CDKN2A PTPRC
2 primary mediastinal large b-cell lymphoma 10.3 BCL6 IRF4
3 bone lymphoma 10.3 BCL6 CD22
4 primary effusion lymphoma 10.3 BCL6 IRF4
5 mediastinal cancer 10.3 CD5 CD79A
6 intravascular large b-cell lymphoma 10.3 BCL6 CD5
7 heart lymphoma 10.3 BCL6 PTPRC
8 central nervous system hematologic cancer 10.2 BCL6 IRF4
9 composite lymphoma 10.2 BCL6 CD5
10 hodgkin's lymphoma, lymphocytic-histiocytic predominance 10.2 BCL6 PTPRC
11 testicular lymphoma 10.2 BCL6 PTPRC
12 relapsed/refractory diffuse large b-cell lymphoma 10.2 CD19 IRF4
13 selective igg deficiency disease 10.2 CD19 CD79A
14 posterior scleritis 10.2 CD19 CD22
15 congenital hypogammaglobulinemia 10.2 CD19 CD79A
16 richter's syndrome 10.2 CD5 IRF4
17 primary cutaneous diffuse large b-cell lymphoma, leg type 10.2 CDKN2A IRF4
18 solitary osseous plasmacytoma 10.2 CD19 CD79A
19 t-cell/histiocyte rich large b cell lymphoma 10.1 BCL6 TNFRSF8
20 lymphoma 10.1
21 cd45 deficiency 10.1 CD5 PTPRC
22 breast lymphoma 10.1 BCL6 CD5 CD79A
23 plasmacytoma 10.1 CD79A IRF4 PTPRC
24 conventional fibrosarcoma 10.1 PTPRC TNFRSF8
25 b cell prolymphocytic leukemia 10.1 CD19 CD5
26 lateral medullary syndrome 10.1 CD19 CD22
27 testicular infarct 10.1 PTPRC TNFRSF8
28 gamma heavy chain disease 10.1 CD19 PTPRC
29 plasma protein metabolism disease 10.1 CD19 CD5
30 reticulum cell sarcoma 10.1 PTPRC TNFRSF8
31 lymphoepithelioma-like thymic carcinoma 10.1 CD5 CDKN2A
32 primary cutaneous anaplastic large cell lymphoma 10.1 ALK IRF4 PTPRC
33 lymphoblastic lymphoma 10.0 BCL6 CD5 PTPRC
34 mediastinal malignant lymphoma 10.0 BCL6 CD79A TNFRSF8
35 bladder lymphoma 10.0 CD19 CD5 CD79A
36 autoimmune lymphoproliferative syndrome, type v 10.0 ALK BCL6 CD5
37 waldenstroem's macroglobulinemia 10.0 CD19 CD22 CD5
38 reticulohistiocytic granuloma 10.0 PTPRC TNFRSF8
39 anterior scleritis 10.0 CD19 CD22 CD5
40 necrotizing sialometaplasia 10.0 CD5 CDKN2A
41 marginal zone b-cell lymphoma 10.0 BCL6 CD5 CD79A IRF4
42 thymus lipoma 10.0 CD5 PTPRC TNFRSF8
43 immune system organ benign neoplasm 9.9 CD5 PTPRC TNFRSF8
44 pityriasis lichenoides 9.9 CD7 TNFRSF8
45 immune deficiency disease 9.9 CD19 CD79A TNFRSF8
46 pityriasis lichenoides et varioliformis acuta 9.9 CD7 TNFRSF8
47 adult lymphoma 9.9 ALK CD5 TNFRSF8
48 ecthyma 9.9 ALK TNFRSF8
49 plasmablastic lymphoma 9.9 BCL6 CDKN2A PTPRC
50 anaplastic large cell lymphoma 9.9 ALK PTPRC TNFRSF8

Graphical network of the top 20 diseases related to Colon Lymphoma:



Diseases related to Colon Lymphoma

Symptoms & Phenotypes for Colon Lymphoma

GenomeRNAi Phenotypes related to Colon Lymphoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 BCL6 CD22 CD5 CD7 CD79A PTPRC

MGI Mouse Phenotypes related to Colon Lymphoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.97 BCL6 CD19 CD22 CD79A CDKN2A IRF4
2 hematopoietic system MP:0005397 9.9 BCL6 CD19 CD22 CD5 CD7 CD79A
3 endocrine/exocrine gland MP:0005379 9.8 ALK BCL6 CD7 CDKN2A PTPRC RFWD3
4 immune system MP:0005387 9.7 BCL6 CD19 CD22 CD5 CD7 CD79A
5 neoplasm MP:0002006 9.17 ALK CD19 CD79A CDKN2A IRF4 MSH6

Drugs & Therapeutics for Colon Lymphoma

Search Clinical Trials , NIH Clinical Center for Colon Lymphoma

Genetic Tests for Colon Lymphoma

Anatomical Context for Colon Lymphoma

MalaCards organs/tissues related to Colon Lymphoma:

42
Colon, B Cells, Thyroid

Publications for Colon Lymphoma

Articles related to Colon Lymphoma:

(show all 12)
# Title Authors Year
1
Secondary thyroid malignancy from metastatic colon lymphoma. ( 30878969 )
2019
2
The management of primary small bowel and colon lymphoma--a review. ( 21912877 )
2012
3
Colon lymphoma causing intussusception. ( 22449682 )
2012
4
Sudden onset of renal failure requiring dialysis associated with large B-cell lymphoma of colon. ( 24475418 )
2012
5
Aggressive Burkitt-like lymphoma of colon in a patient with prior celiac disease. ( 17940628 )
2006
6
Primary colon lymphoma in Korea: a KASID (Korean Association for the Study of Intestinal Diseases) Study. ( 16416168 )
2005
7
Mantle-cell lymphoma of colon. ( 15729249 )
2005
8
Unusual abdominal tumors: case 3. Multiple lymphomatous polyposis in lymphoma of colon. ( 12610202 )
2003
9
Unexpected detection of colon lymphoma on a Tc-99m-labeled red blood cell abdominal scan. ( 11129152 )
2000
10
Successful nonsurgical treatment of primary mucosa-associated lymphoid tissue lymphoma of colon presenting with multiple polypoid lesions. ( 11007252 )
2000
11
Primary low grade B-cell lymphoma of colon mimicking inflammatory bowel disease: a case report. ( 9294917 )
1997
12
Hodgkin's lymphoma of colon: an unusual cause of isolated splenic vein obstruction. ( 8206544 )
1994

Variations for Colon Lymphoma

Expression for Colon Lymphoma

Search GEO for disease gene expression data for Colon Lymphoma.

Pathways for Colon Lymphoma

GO Terms for Colon Lymphoma

Cellular components related to Colon Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.92 CD19 CD5 CD79A PTPRC

Biological processes related to Colon Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of immune response GO:0050776 9.58 BCL6 CD19 CD22
2 B cell receptor signaling pathway GO:0050853 9.43 CD19 CD79A PTPRC
3 B cell proliferation GO:0042100 9.37 CD79A PTPRC
4 negative regulation of cell-matrix adhesion GO:0001953 9.32 BCL6 CDKN2A
5 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.16 IRF4 PTPRC
6 B cell differentiation GO:0030183 9.13 BCL6 CD79A PTPRC
7 T cell activation GO:0042110 8.8 CD7 IRF4 PTPRC

Molecular functions related to Colon Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.8 CD5 CD79A TNFRSF8

Sources for Colon Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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