MCID: CLR079
MIFTS: 18

Colorectal Cancer 2

Categories: Cancer diseases, Genetic diseases, Gastrointestinal diseases, Rare diseases

Aliases & Classifications for Colorectal Cancer 2

MalaCards integrated aliases for Colorectal Cancer 2:

Name: Colorectal Cancer 2 57 29
Colorectal Cancer, Susceptibility to, 2 57 13
Colorectal Cancer, Susceptibility to, on Chromosome 8q24 57
Colorectal Cancer on Chromosome 8q24 57
Crcs2 57

Classifications:



External Ids:

OMIM 57 611469

Summaries for Colorectal Cancer 2

MalaCards based summary : Colorectal Cancer 2, also known as colorectal cancer, susceptibility to, 2, is related to colorectal cancer, hereditary nonpolyposis, type 2 and colorectal cancer. An important gene associated with Colorectal Cancer 2 is CRCS2 (Colorectal Cancer, Susceptibility To, 2). Affiliated tissues include appendix, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Description from OMIM: 611469

Related Diseases for Colorectal Cancer 2

Diseases in the Colorectal Cancer family:

Colorectal Cancer 1 Colorectal Cancer 2
Colorectal Cancer 3 Colorectal Cancer 5
Colorectal Cancer 6 Colorectal Cancer 7
Colorectal Cancer 8 Colorectal Cancer 9
Colorectal Cancer 10 Colorectal Cancer 11
Colorectal Cancer 12 Familial Colorectal Cancer
Familial Colorectal Cancer Type X

Diseases related to Colorectal Cancer 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 colorectal cancer, hereditary nonpolyposis, type 2 11.6
2 colorectal cancer 9.8

Symptoms & Phenotypes for Colorectal Cancer 2

Clinical features from OMIM:

611469

GenomeRNAi Phenotypes related to Colorectal Cancer 2 according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-1 9.61 MLH1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.61 MLH1
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-109 9.61 TK1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.61 MLH1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.61 TK1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-191 9.61 TK1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.61 MLH1 TK1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.61 TK1
9 Increased viability with MLN4924 (a NAE inhibitor) GR00250-A-3 8.62 MLH1 TK1

Drugs & Therapeutics for Colorectal Cancer 2

Search Clinical Trials , NIH Clinical Center for Colorectal Cancer 2

Genetic Tests for Colorectal Cancer 2

Genetic tests related to Colorectal Cancer 2:

# Genetic test Affiliating Genes
1 Colorectal Cancer 2 29

Anatomical Context for Colorectal Cancer 2

MalaCards organs/tissues related to Colorectal Cancer 2:

41
Appendix

Publications for Colorectal Cancer 2

Articles related to Colorectal Cancer 2:

# Title Authors Year
1
appendix 5: Metastatic colorectal cancer (2): eUpdate published online August 2016 (www.esmo.org/Guidelines/Gastrointestinal-Cancers). ( 27664253 )
2016
2
Colorectal cancer: 2 steps backward. ( 19820071 )
2009

Variations for Colorectal Cancer 2

Expression for Colorectal Cancer 2

Search GEO for disease gene expression data for Colorectal Cancer 2.

Pathways for Colorectal Cancer 2

GO Terms for Colorectal Cancer 2

Sources for Colorectal Cancer 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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