MCID: CMM006
MIFTS: 23

Commensal Bacterial Infectious Disease

Categories: Infectious diseases

Aliases & Classifications for Commensal Bacterial Infectious Disease

MalaCards integrated aliases for Commensal Bacterial Infectious Disease:

Name: Commensal Bacterial Infectious Disease 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050339

Summaries for Commensal Bacterial Infectious Disease

Disease Ontology : 12 A bacterial infectious disease that results in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder.

MalaCards based summary : Commensal Bacterial Infectious Disease is related to chlamydia and pertussis. An important gene associated with Commensal Bacterial Infectious Disease is TST (Thiosulfate Sulfurtransferase), and among its related pathways/superpathways are Allograft rejection and Th17 cell differentiation. Related phenotype is Increased transferrin (TF) endocytosis.

Related Diseases for Commensal Bacterial Infectious Disease

Diseases related to Commensal Bacterial Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
# Related Disease Score Top Affiliating Genes
1 chlamydia 32.6 TNF IL6 IL1B IL10
2 pertussis 32.5 TNF IL6 IL1B IL10
3 toxic shock syndrome 32.3 TNF MYOM2 IL6 IL1B IL10
4 trachoma 11.4
5 lemierre's syndrome 11.4
6 inclusion conjunctivitis 11.4
7 lymphogranuloma venereum 11.4
8 actinobacillosis 11.4
9 actinomycosis 11.4
10 ritter's disease 11.4
11 gas gangrene 11.4
12 ventilation pneumonitis 10.7 TNF CD4
13 punctate inner choroidopathy 10.7 TNF IL10
14 exudative glomerulonephritis 10.7 TNF IL1B
15 scorpion envenomation 10.7 TNF IL6
16 tropical endomyocardial fibrosis 10.7 TNF IL10
17 endomyocardial fibrosis 10.7 TNF IL10
18 staphyloenterotoxemia 10.7 SETBP1 FUT2 EPHX2
19 staphylococcal toxic shock syndrome 10.6 TNF IL1B
20 pneumocystosis 10.6 TNF CD40LG CD4
21 bullous impetigo 10.6 IL6 EDNRB
22 angioimmunoblastic lymphadenopathy with dysproteinemia 10.6 TNF IL6
23 recurrent corneal erosion 10.6 IL6 IL1B
24 impetigo 10.6 MYOM2 IL6 EDNRB
25 bagassosis 10.6 IL6 IL1B
26 streptococcal toxic-shock syndrome 10.6 TNF MYOM2 IL6
27 autoimmune myocarditis 10.6 TNF IL6
28 multifocal choroiditis 10.6 TNF IL10
29 chronic graft versus host disease 10.6 TNF IL10 CD4
30 laryngitis 10.5 TNF IL6 IL1B
31 glossitis 10.5 TNF IL6 IL1B
32 polyclonal hypergammaglobulinemia 10.5 MYOM2 IL6 CD4
33 acute vascular insufficiency of intestine 10.5 TNF IL6 IL1B
34 periapical periodontitis 10.5 TNF IL6 IL1B
35 monoclonal gammopathy of uncertain significance 10.5 TNF MYOM2 IL6
36 stachybotrys chartarum 10.5 TNF IL6 IL1B
37 central nervous system vasculitis 10.5 TNF IL6 IL1B
38 endometrial disease 10.5 TNF IL6 IL1B
39 endometritis 10.5 TNF IL6 IL1B
40 pulpitis 10.5 TNF IL6 IL1B
41 tungiasis 10.5 TNF IL10
42 middle ear disease 10.5 TNF IL6 IL1B
43 primary systemic mycosis 10.5 TNF IL1B IL10
44 adult-onset still's disease 10.5 TNF IL6 IL1B
45 perinatal necrotizing enterocolitis 10.5 TNF IL6 IL1B
46 dengue shock syndrome 10.5 TNF IL6 IL1B
47 acute respiratory distress syndrome 10.5 TNF IL6 IL1B
48 scrub typhus 10.5 TNF IL1B IL10
49 aseptic meningitis 10.5 TNF IL1B IL10
50 transverse myelitis 10.5 TNF IL6 IL10

Graphical network of the top 20 diseases related to Commensal Bacterial Infectious Disease:



Diseases related to Commensal Bacterial Infectious Disease

Symptoms & Phenotypes for Commensal Bacterial Infectious Disease

GenomeRNAi Phenotypes related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased transferrin (TF) endocytosis GR00363-A 9.44 CD4 CD40LG CIAO3 EDNRB EPHX2 FUT2

Drugs & Therapeutics for Commensal Bacterial Infectious Disease

Search Clinical Trials , NIH Clinical Center for Commensal Bacterial Infectious Disease

Genetic Tests for Commensal Bacterial Infectious Disease

Anatomical Context for Commensal Bacterial Infectious Disease

Publications for Commensal Bacterial Infectious Disease

Variations for Commensal Bacterial Infectious Disease

Expression for Commensal Bacterial Infectious Disease

Search GEO for disease gene expression data for Commensal Bacterial Infectious Disease.

Pathways for Commensal Bacterial Infectious Disease

Pathways related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 35)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.82 TNF IL6 IL1B IL10 CD40LG CD4
2
Show member pathways
12.53 TNF IL6 IL1B IL10 CD4
3
Show member pathways
12.52 TNF IL6 IL1B IL10 CD4
4
Show member pathways
12.39 TNF IL6 IL1B IL10 CD40LG CD4
5
Show member pathways
12.29 TNF SELENOO IL6 IL1B
6
Show member pathways
12.22 TNF IL1B IL10 CD40LG
7 12.19 TNF IL6 IL1B IL10
8
Show member pathways
12.16 TNF IL6 IL1B IL10
9 12.13 TNF IL6 IL1B IL10
10 11.93 TNF IL6 IL10 CD4
11 11.92 TNF IL6 IL1B IL10
12
Show member pathways
11.92 TNF IL6 IL1B IL10 CD4
13 11.85 TNF IL1B CD40LG
14 11.85 TNF IL6 IL1B IL10
15 11.84 TNF IL6 IL1B
16 11.84 TNF IL6 IL1B CD4
17 11.8 TNF IL6 IL1B
18 11.73 TNF IL1B IL10 CD4
19 11.69 TNF IL6 IL1B IL10
20 11.63 TNF IL6 IL1B IL10
21 11.62 TNF IL6 IL1B
22 11.56 TNF IL6 IL1B
23
Show member pathways
11.56 TNF IL6 IL1B CD40LG
24 11.53 IL10 CD40LG CD4
25 11.44 TNF IL6 IL1B
26 11.42 TNF IL6 IL1B IL10
27 11.42 TNF IL6 IL1B IL10 CD4
28 11.27 TNF IL6 IL1B
29 11.24 TNF IL6 IL1B
30 11.17 TNF IL6 IL1B IL10
31 11.13 TNF IL6 IL1B IL10
32 11.12 TNF IL6 IL1B IL10 CD40LG
33 11.04 TNF IL6 IL1B IL10 CD40LG
34 10.96 TNF IL6 IL1B IL10 CD40LG
35 10.48 TNF IL6 IL1B IL10 CD4

GO Terms for Commensal Bacterial Infectious Disease

Biological processes related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.95 TNF IL6 IL1B IL10 CD40LG CD4
2 positive regulation of protein phosphorylation GO:0001934 9.89 TNF IL1B EDNRB CD4
3 cytokine-mediated signaling pathway GO:0019221 9.89 TNF IL6 IL1B IL10 CD4
4 inflammatory response GO:0006954 9.88 TNF IL6 IL1B IL10 EPHX2 CD40LG
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.86 TNF IL6 IL1B CD40LG
6 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.8 TNF CD4 APELA
7 positive regulation of interleukin-6 production GO:0032755 9.77 TNF IL6 IL1B
8 positive regulation of DNA-binding transcription factor activity GO:0051091 9.76 TNF IL6 IL1B IL10
9 negative regulation of growth of symbiont in host GO:0044130 9.64 TNF IL10
10 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.63 IL1B CD4
11 negative regulation of lipid storage GO:0010888 9.62 TNF IL6
12 positive regulation of chemokine biosynthetic process GO:0045080 9.62 TNF IL1B
13 endothelial cell apoptotic process GO:0072577 9.61 TNF IL10
14 regulation of establishment of endothelial barrier GO:1903140 9.61 TNF IL1B
15 negative regulation of neurogenesis GO:0050768 9.61 TNF IL6 IL1B
16 negative regulation of cytokine secretion involved in immune response GO:0002740 9.58 TNF IL10
17 regulation of immunoglobulin secretion GO:0051023 9.58 TNF CD40LG
18 positive regulation of fever generation GO:0031622 9.57 TNF IL1B
19 sequestering of triglyceride GO:0030730 9.55 TNF IL1B
20 cellular response to lipopolysaccharide GO:0071222 9.55 TNF IL6 IL1B IL10 EDNRB
21 positive regulation of glial cell proliferation GO:0060252 9.54 TNF IL6 IL1B
22 receptor biosynthetic process GO:0032800 9.52 TNF IL10
23 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.51 TNF IL1B
24 response to glucocorticoid GO:0051384 9.5 TNF IL6 IL10
25 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.43 TNF IL1B IL10
26 positive regulation of T cell proliferation GO:0042102 9.26 IL6 IL1B CD40LG CD4
27 chronic inflammatory response to antigenic stimulus GO:0002439 9.24 TNF
28 positive regulation of neuroinflammatory response GO:0150078 8.8 TNF IL6 IL1B

Molecular functions related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 TNF IL6 IL1B IL10 CD40LG

Sources for Commensal Bacterial Infectious Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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