MCID: CMM006
MIFTS: 29

Commensal Bacterial Infectious Disease

Categories: Infectious diseases

Aliases & Classifications for Commensal Bacterial Infectious Disease

MalaCards integrated aliases for Commensal Bacterial Infectious Disease:

Name: Commensal Bacterial Infectious Disease 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050339

Summaries for Commensal Bacterial Infectious Disease

Disease Ontology : 12 A bacterial infectious disease that results in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder.

MalaCards based summary : Commensal Bacterial Infectious Disease is related to ritter's disease and chlamydia. An important gene associated with Commensal Bacterial Infectious Disease is DPT (Dermatopontin), and among its related pathways/superpathways are Allograft rejection and Th17 cell differentiation. Affiliated tissues include lung, liver and bone, and related phenotype is integument.

Related Diseases for Commensal Bacterial Infectious Disease

Diseases related to Commensal Bacterial Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 213)
# Related Disease Score Top Affiliating Genes
1 ritter's disease 32.4 DSG1 EDNRB
2 chlamydia 32.0 IL10 IL1B IL6 TNF
3 pertussis 32.0 IL10 IL1B IL6 TNF
4 toxic shock syndrome 31.7 IL10 IL1B IL2 IL6 MYOM2 TNF
5 gas gangrene 11.3
6 trachoma 11.3
7 lemierre's syndrome 11.3
8 inclusion conjunctivitis 11.3
9 lymphogranuloma venereum 11.3
10 actinobacillosis 11.3
11 actinomycosis 11.3
12 staphyloenterotoxemia 10.3 FUT2 SETBP1
13 critical limb ischemia 10.3 IL6 TNF
14 cardiogenic shock 10.3 IL6 TNF
15 extramedullary plasmacytoma 10.3 IL6 MYOM2
16 periodontitis, chronic 10.3 IL1B IL6
17 microscopic polyangiitis 10.3 IL10 TNF
18 multifocal choroiditis 10.3 IL10 TNF
19 paraneoplastic syndromes 10.3 IL1B IL6
20 autoimmune vasculitis 10.3 IL1B IL2
21 exudative glomerulonephritis 10.3 IL1B TNF
22 oral tuberculosis 10.3 IL2 TNF
23 punctate inner choroidopathy 10.3 IL10 TNF
24 eye lymphoma 10.3 IL10 IL6
25 acute transverse myelitis 10.3 IL10 IL6
26 scorpion envenomation 10.3 IL6 TNF
27 tropical endomyocardial fibrosis 10.2 IL10 TNF
28 endomyocardial fibrosis 10.2 IL10 TNF
29 peripheral nervous system disease 10.2 IL6 MYOM2 TNF
30 loiasis 10.2 IL10 PHB2
31 periodontal disease 10.2 IL1B IL6 TNF
32 tungiasis 10.2 DPT IL10 TNF
33 rheumatic disease 10.2 IL10 IL1B TNF
34 demyelinating disease 10.2 IL10 IL1B TNF
35 glossitis 10.2 IL1B IL6 TNF
36 laryngitis 10.2 IL1B IL6 TNF
37 acute vascular insufficiency of intestine 10.2 IL1B IL6 TNF
38 periapical periodontitis 10.2 IL1B IL6 TNF
39 poliomyelitis 10.2 DPT IL10 TNF
40 central nervous system vasculitis 10.2 IL1B IL6 TNF
41 stachybotrys chartarum 10.2 IL1B IL6 TNF
42 monoclonal gammopathy of uncertain significance 10.2 IL6 MYOM2 TNF
43 endometrial disease 10.2 IL1B IL6 TNF
44 crohn's colitis 10.2 IL1B IL2 TNF
45 endometritis 10.2 IL1B IL6 TNF
46 pulpitis 10.2 IL1B IL6 TNF
47 joint disorders 10.2 IL1B IL6 TNF
48 bullous impetigo 10.2 DSG1 EDNRB IL6
49 middle ear disease 10.2 IL1B IL6 TNF
50 adult-onset still's disease 10.2 IL1B IL6 TNF

Graphical network of the top 20 diseases related to Commensal Bacterial Infectious Disease:



Diseases related to Commensal Bacterial Infectious Disease

Symptoms & Phenotypes for Commensal Bacterial Infectious Disease

MGI Mouse Phenotypes related to Commensal Bacterial Infectious Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.23 DPT DSG1 EDNRB IL10 IL1B IL6

Drugs & Therapeutics for Commensal Bacterial Infectious Disease

Search Clinical Trials , NIH Clinical Center for Commensal Bacterial Infectious Disease

Genetic Tests for Commensal Bacterial Infectious Disease

Anatomical Context for Commensal Bacterial Infectious Disease

MalaCards organs/tissues related to Commensal Bacterial Infectious Disease:

41
Lung, Liver, Bone, Heart, Lymph Node, Eye, Prostate

Publications for Commensal Bacterial Infectious Disease

Variations for Commensal Bacterial Infectious Disease

Expression for Commensal Bacterial Infectious Disease

Search GEO for disease gene expression data for Commensal Bacterial Infectious Disease.

Pathways for Commensal Bacterial Infectious Disease

Pathways related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 36)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.83 IL10 IL1B IL2 IL6 KLRC3 TNF
2
Show member pathways
12.55 IL10 IL1B IL2 IL6 TNF
3
Show member pathways
12.53 IL10 IL1B IL2 IL6 TNF
4
Show member pathways
12.35 IL10 IL1B IL2 IL6 TNF
5
Show member pathways
12.29 IL1B IL2 IL6 TNF
6
Show member pathways
12.21 IL10 IL1B IL2 IL6 TNF
7 12.2 IL10 IL1B IL6 TNF
8 12.14 IL10 IL1B IL6 TNF
9
Show member pathways
12.11 IL10 IL1B IL2 IL6 TNF
10 11.96 IL1B IL2 IL6 TNF
11 11.93 IL10 IL2 IL6 TNF
12 11.92 IL10 IL1B IL6 TNF
13
Show member pathways
11.88 IL10 IL1B IL2 IL6 TNF
14 11.84 IL1B IL6 TNF
15 11.83 IL1B IL6 TNF
16 11.82 IL10 IL1B IL6 TNF
17 11.79 IL1B IL6 TNF
18 11.73 IL10 IL1B IL2 TNF
19 11.69 IL10 IL1B IL6 TNF
20 11.63 IL1B IL6 TNF
21 11.56 IL1B IL6 TNF
22
Show member pathways
11.56 IL1B IL2 IL6 TNF
23 11.52 IL2 IL6 TNF
24 11.49 IL1B IL2 TNF
25 11.45 IL1B IL6 TNF
26 11.42 IL10 IL1B IL6 TNF
27 11.42 IL10 IL1B IL2 IL6 TNF
28 11.4 IL10 IL1B IL6 TNF
29 11.27 IL1B IL6 TNF
30 11.24 IL1B IL6 TNF
31 11.2 IL10 IL1B IL2 IL6 TNF
32 11.17 IL10 IL1B IL6 TNF
33 11.12 IL10 IL1B IL2 IL6 TNF
34 11.1 IL10 IL1B IL6 TNF
35 10.96 IL10 IL1B IL2 IL6 TNF
36 10.48 IL10 IL1B IL2 IL6 TNF

GO Terms for Commensal Bacterial Infectious Disease

Biological processes related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.99 DPT GTPBP4 IL10 IL1B IL6
2 positive regulation of protein phosphorylation GO:0001934 9.87 EDNRB IL1B IL2 TNF
3 cytokine-mediated signaling pathway GO:0019221 9.85 IL10 IL1B IL2 IL6 TNF
4 positive regulation of interleukin-6 production GO:0032755 9.76 IL1B IL6 TNF
5 positive regulation of interferon-gamma production GO:0032729 9.71 IL1B IL2 TNF
6 response to glucocorticoid GO:0051384 9.67 IL10 IL1B IL6 TNF
7 cellular response to lipopolysaccharide GO:0071222 9.65 EDNRB IL10 IL1B IL6 TNF
8 negative regulation of growth of symbiont in host GO:0044130 9.63 IL10 TNF
9 positive regulation of immunoglobulin secretion GO:0051024 9.63 IL2 IL6
10 negative regulation of lipid storage GO:0010888 9.62 IL6 TNF
11 endothelial cell apoptotic process GO:0072577 9.61 IL10 TNF
12 negative regulation of neurogenesis GO:0050768 9.61 IL1B IL6 TNF
13 positive regulation of chemokine biosynthetic process GO:0045080 9.6 IL1B TNF
14 regulation of establishment of endothelial barrier GO:1903140 9.58 IL1B TNF
15 positive regulation of glial cell proliferation GO:0060252 9.58 IL1B IL6 TNF
16 negative regulation of cytokine secretion involved in immune response GO:0002740 9.56 IL10 TNF
17 positive regulation of fever generation GO:0031622 9.55 IL1B TNF
18 chronic inflammatory response to antigenic stimulus GO:0002439 9.52 IL1B TNF
19 sequestering of triglyceride GO:0030730 9.51 IL1B TNF
20 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.5 IL10 IL1B TNF
21 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.49 IL1B TNF
22 receptor biosynthetic process GO:0032800 9.48 IL10 TNF
23 positive regulation of T cell proliferation GO:0042102 9.46 BTNL2 IL1B IL2 IL6
24 positive regulation of DNA-binding transcription factor activity GO:0051091 9.35 IL10 IL1B IL6 PHB2 TNF
25 positive regulation of neuroinflammatory response GO:0150078 8.8 IL1B IL6 TNF
26 negative regulation of apoptotic process GO:0043066 10.04 EDNRB IL10 IL2 IL6 PHB2
27 immune response GO:0006955 10.02 IL10 IL1B IL2 IL6 TNF
28 regulation of signaling receptor activity GO:0010469 10.01 IL10 IL1B IL2 IL6 TNF

Molecular functions related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL10 IL1B IL2 IL6 TNF

Sources for Commensal Bacterial Infectious Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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