MCID: CMM006
MIFTS: 27

Commensal Bacterial Infectious Disease

Categories: Infectious diseases

Aliases & Classifications for Commensal Bacterial Infectious Disease

MalaCards integrated aliases for Commensal Bacterial Infectious Disease:

Name: Commensal Bacterial Infectious Disease 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050339

Summaries for Commensal Bacterial Infectious Disease

Disease Ontology : 12 A bacterial infectious disease that results in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder.

MalaCards based summary : Commensal Bacterial Infectious Disease is related to inclusion conjunctivitis and ritter's disease. An important gene associated with Commensal Bacterial Infectious Disease is CCR6 (C-C Motif Chemokine Receptor 6), and among its related pathways/superpathways are Allograft rejection and Immune response NFAT in immune response. Affiliated tissues include lung, bone and skin, and related phenotypes are cardiovascular system and immune system

Related Diseases for Commensal Bacterial Infectious Disease

Diseases related to Commensal Bacterial Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 588)
# Related Disease Score Top Affiliating Genes
1 inclusion conjunctivitis 33.3 NAT9 ESCO2 CD40LG
2 ritter's disease 33.2 TST SETBP1 EPHX2 EDNRB
3 actinomycosis 33.2 H2AC18 CD4 ADD2
4 trachoma 33.1 TNF IL6 IL10
5 chlamydia 33.0 TNF TLR4 IL6 IL10 CD40LG
6 pertussis 33.0 TNF TLR4 IL6 IL10
7 toxic shock syndrome 32.9 TNF TLR4 MYOM2 IL6 IL10 CD40LG
8 lemierre's syndrome 11.4
9 lymphogranuloma venereum 11.4
10 actinobacillosis 11.4
11 gas gangrene 11.4
12 external pathological resorption 10.8 TNF IL6
13 riedel's fibrosing thyroiditis 10.8 CD40LG CD4
14 punctate inner choroidopathy 10.8 TNF IL10
15 chancroid 10.8 CD40LG CD4 CCR6
16 spongiotic dermatitis 10.8 CD8A CD4 CCR6
17 granuloma inguinale 10.8 NAT9 ESCO2 CD4
18 ornithosis 10.8 NAT9 ESCO2 CD40LG
19 conjunctivitis 10.8 TNF IL6 IL10
20 cork-handlers' disease 10.8 CD8A CD40LG CD4
21 scorpion envenomation 10.8 TNF IL6
22 syphilitic meningitis 10.7 CD8A CD40LG CD4
23 tropical endomyocardial fibrosis 10.7 TNF IL10
24 autoimmune neuropathy 10.7 ICOSLG CD40LG CD4
25 igg4-related disease 10.7 ICOSLG CD4 CCR6
26 osteosclerotic myeloma 10.7 MYOM2 IL6 CD40LG
27 mononeuritis of upper limb and mononeuritis multiplex 10.7 MYOM2 CD40LG CD4
28 mononeuritis multiplex 10.7 MYOM2 CD40LG CD4
29 esophageal candidiasis 10.7 CD8A CD4 CCR6
30 early yaws 10.7 CD8A CD40LG CD4
31 streptococcal toxic-shock syndrome 10.7 TNF MYOM2 IL6
32 diabetes mellitus, insulin-dependent, 23 10.7 TNF CD8A CD4
33 norwegian scabies 10.7 CD8A CD40LG CD4
34 gastrointestinal tuberculosis 10.7 TNF CD40LG CD4
35 pustulosis palmaris et plantaris 10.7 TNF CD40LG CCR6
36 tertiary syphilis 10.7 CD8A CD40LG CD4
37 acute retinal necrosis syndrome 10.7 CD8A CD40LG CD4
38 immunodeficiency with hyper-igm, type 2 10.7 ICOSLG H2AC18 CD40LG
39 granulomatous hepatitis 10.7 CD8A CD40LG CD4
40 granulomatous dermatitis 10.7 TNF CD40LG CD4
41 spondyloarthropathy 10.7 TNF IL6 IL10
42 tuberculoid leprosy 10.7 IL10 CD4 CCR6
43 west nile encephalitis 10.7 CD8A CD40LG CD4
44 abdominal tuberculosis 10.7 TNF CD40LG CD4
45 t-cell adult acute lymphocytic leukemia 10.7 CD8A CD4 CCR6
46 corticosteroid allergy 10.7 NAT9 CD8A CD4
47 adult acute lymphocytic leukemia 10.7 CD8A CD4 CCR6
48 neurosarcoidosis 10.7 TNF CD8A CD4
49 cerebritis 10.7 CD8A CD40LG CD4
50 parotid disease 10.7 CD8A CD40LG CD4

Graphical network of the top 20 diseases related to Commensal Bacterial Infectious Disease:



Diseases related to Commensal Bacterial Infectious Disease

Symptoms & Phenotypes for Commensal Bacterial Infectious Disease

MGI Mouse Phenotypes related to Commensal Bacterial Infectious Disease:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.85 ADD2 CCR6 CD40LG EDNRB EPHX2 IL10
2 immune system MP:0005387 9.7 ADD2 CCR6 CD4 CD40LG CD8A EDNRB
3 nervous system MP:0003631 9.4 ADD2 CCR6 CD4 CD40LG CD8A EDNRB

Drugs & Therapeutics for Commensal Bacterial Infectious Disease

Search Clinical Trials , NIH Clinical Center for Commensal Bacterial Infectious Disease

Genetic Tests for Commensal Bacterial Infectious Disease

Anatomical Context for Commensal Bacterial Infectious Disease

MalaCards organs/tissues related to Commensal Bacterial Infectious Disease:

40
Lung, Bone, Skin, Eye, T Cells, B Cells, Thymus

Publications for Commensal Bacterial Infectious Disease

Variations for Commensal Bacterial Infectious Disease

Expression for Commensal Bacterial Infectious Disease

Search GEO for disease gene expression data for Commensal Bacterial Infectious Disease.

Pathways for Commensal Bacterial Infectious Disease

Pathways related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 27)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.74 TNF IL6 IL10 ICOSLG CD8A CD40LG
2
Show member pathways
12.55 TNF IL10 ICOSLG CD40LG CD4
3
Show member pathways
12.5 TNF TLR4 IL6 IL10 CD4
4
Show member pathways
12.34 TNF TLR4 IL6 IL10 CD8A CD40LG
5
Show member pathways
12.26 TNF IL6 IL10 CCR6
6
Show member pathways
12.19 TNF TLR4 IL10 CD40LG
7 12.15 TNF TLR4 IL6 IL10
8 12.03 ICOSLG CD8A CD40LG CD4
9
Show member pathways
11.94 TNF TLR4 IL6 IL10 CD4
10 11.9 TNF TLR4 IL6 IL10
11 11.87 TNF IL6 IL10 CD8A CD4
12 11.82 TNF TLR4 IL6 IL10
13 11.79 TNF IL6 CD8A CD4
14 11.67 TNF TLR4 CD4
15 11.66 TNF IL6 IL10
16 11.66 TNF TLR4 IL6 IL10
17
Show member pathways
11.59 TNF IL6 CD40LG
18 11.54 TNF TLR4 IL6
19 11.48 IL10 CD40LG CD4
20 11.46 TNF IL10 CD8A CD4 CCR6
21 11.44 TNF IL6 IL10
22 11.3 CD8A CD40LG CD4
23 11.28 TNF IL6 IL10
24 11.22 TNF IL6 IL10 CD8A CD4
25 11.21 TNF TLR4 IL6 IL10
26 11.09 TNF IL6 IL10 CD4
27 10.72 TNF TLR4 IL6 IL10 CD40LG

GO Terms for Commensal Bacterial Infectious Disease

Cellular components related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.17 TNF TLR4 ICOSLG CD8A CD40LG CD4

Biological processes related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 response to glucocorticoid GO:0051384 9.73 TNF IL6 IL10
2 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.73 TNF TLR4 IL6 CD40LG
3 positive regulation of T cell proliferation GO:0042102 9.71 IL6 CD40LG CD4
4 positive regulation of interleukin-6 production GO:0032755 9.7 TNF TLR4 IL6
5 humoral immune response GO:0006959 9.69 TNF IL6 CCR6
6 T cell activation GO:0042110 9.65 ICOSLG CD8A CD4
7 inflammatory response GO:0006954 9.63 TNF TLR4 IL6 IL10 EPHX2 CD40LG
8 positive regulation of MHC class II biosynthetic process GO:0045348 9.58 TLR4 IL10
9 negative regulation of interleukin-6 production GO:0032715 9.58 TNF TLR4 IL10
10 negative regulation of lipid storage GO:0010888 9.57 TNF IL6
11 endothelial cell apoptotic process GO:0072577 9.55 TNF IL10
12 positive regulation of JAK-STAT cascade GO:0046427 9.5 TNF IL6 IL10
13 negative regulation of cytokine secretion involved in immune response GO:0002740 9.49 TNF IL10
14 regulation of immunoglobulin secretion GO:0051023 9.46 TNF CD40LG
15 positive regulation of chemokine production GO:0032722 9.43 TNF TLR4 IL6
16 receptor biosynthetic process GO:0032800 9.37 TNF IL10
17 cellular response to lipopolysaccharide GO:0071222 9.35 TNF TLR4 IL6 IL10 EDNRB
18 immune response GO:0006955 9.23 TNF TLR4 IL6 IL10 CD8A CD40LG

Molecular functions related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 TNF IL6 IL10 CD40LG

Sources for Commensal Bacterial Infectious Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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