MCID: CMM006
MIFTS: 29

Commensal Bacterial Infectious Disease

Categories: Infectious diseases

Aliases & Classifications for Commensal Bacterial Infectious Disease

MalaCards integrated aliases for Commensal Bacterial Infectious Disease:

Name: Commensal Bacterial Infectious Disease 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050339

Summaries for Commensal Bacterial Infectious Disease

Disease Ontology : 12 A bacterial infectious disease that results in infection by bacteria which are part of the normal human flora when one or more of the defense mechanisms designed to restrict them from the usually sterile internal tissues are breached by accident, by intent (surgery), or by an underlying metabolic or an infectious disorder.

MalaCards based summary : Commensal Bacterial Infectious Disease is related to ritter's disease and chlamydia. An important gene associated with Commensal Bacterial Infectious Disease is TST (Thiosulfate Sulfurtransferase), and among its related pathways/superpathways are Th17 cell differentiation and Immune response IL-23 signaling pathway. Affiliated tissues include lung, eye and bone, and related phenotypes are Increased transferrin (TF) endocytosis and vision/eye

Related Diseases for Commensal Bacterial Infectious Disease

Diseases related to Commensal Bacterial Infectious Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 206)
# Related Disease Score Top Affiliating Genes
1 ritter's disease 32.7 DSG1 EDNRB
2 chlamydia 32.2 IL10 IL1B IL6 TNF
3 pertussis 32.2 IL10 IL1B IL6 TNF
4 toxic shock syndrome 31.7 IL10 IL1B IL2 IL6 MYOM2 TNF
5 gas gangrene 11.3
6 trachoma 11.3
7 lemierre's syndrome 11.3
8 inclusion conjunctivitis 11.3
9 lymphogranuloma venereum 11.3
10 actinobacillosis 11.3
11 actinomycosis 11.3
12 critical limb ischemia 10.5 IL6 TNF
13 juvenile ankylosing spondylitis 10.5 IL6 TNF
14 autoimmune myocarditis 10.5 IL6 TNF
15 cardiogenic shock 10.5 IL6 TNF
16 periodontitis, chronic 10.5 IL1B IL6
17 autoimmune vasculitis 10.5 IL1B IL2
18 multifocal choroiditis 10.5 IL10 TNF
19 eye lymphoma 10.4 IL10 IL6
20 acute transverse myelitis 10.4 IL10 IL6
21 oral tuberculosis 10.4 IL2 TNF
22 exudative glomerulonephritis 10.4 IL1B TNF
23 staphyloenterotoxemia 10.4 EPHX2 FUT2 SETBP1
24 scorpion envenomation 10.4 IL6 TNF
25 punctate inner choroidopathy 10.4 IL10 TNF
26 tropical endomyocardial fibrosis 10.4 IL10 TNF
27 endomyocardial fibrosis 10.4 IL10 TNF
28 peripheral nervous system disease 10.4 IL6 MYOM2 TNF
29 periodontal disease 10.4 IL1B IL6 TNF
30 tungiasis 10.3 DPT IL10 TNF
31 sarcoidosis 1 10.3 IL1B IL2 TNF
32 bullous impetigo 10.3 DSG1 EDNRB IL6
33 glossitis 10.3 IL1B IL6 TNF
34 laryngitis 10.3 IL1B IL6 TNF
35 poliomyelitis 10.3 DPT IL10 TNF
36 rheumatic disease 10.3 IL10 IL1B TNF
37 acute vascular insufficiency of intestine 10.3 IL1B IL6 TNF
38 demyelinating disease 10.3 IL10 IL1B TNF
39 periapical periodontitis 10.3 IL1B IL6 TNF
40 central nervous system vasculitis 10.3 IL1B IL6 TNF
41 stachybotrys chartarum 10.3 IL1B IL6 TNF
42 endometrial disease 10.3 IL1B IL6 TNF
43 monoclonal gammopathy of uncertain significance 10.3 IL6 MYOM2 TNF
44 endometritis 10.3 IL1B IL6 TNF
45 pulpitis 10.3 IL1B IL6 TNF
46 joint disorders 10.3 IL1B IL6 TNF
47 crohn's colitis 10.3 IL1B IL2 TNF
48 middle ear disease 10.3 IL1B IL6 TNF
49 adult-onset still's disease 10.3 IL1B IL6 TNF
50 perinatal necrotizing enterocolitis 10.3 IL1B IL6 TNF

Graphical network of the top 20 diseases related to Commensal Bacterial Infectious Disease:



Diseases related to Commensal Bacterial Infectious Disease

Symptoms & Phenotypes for Commensal Bacterial Infectious Disease

GenomeRNAi Phenotypes related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased transferrin (TF) endocytosis GR00363-A 9.4 CIAO3 EDNRB EPHX2 FUT2 GTPBP4 IL10

MGI Mouse Phenotypes related to Commensal Bacterial Infectious Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 9.23 DPT DSG1 EDNRB EPHX2 IL10 IL2

Drugs & Therapeutics for Commensal Bacterial Infectious Disease

Search Clinical Trials , NIH Clinical Center for Commensal Bacterial Infectious Disease

Genetic Tests for Commensal Bacterial Infectious Disease

Anatomical Context for Commensal Bacterial Infectious Disease

MalaCards organs/tissues related to Commensal Bacterial Infectious Disease:

42
Lung, Eye, Bone, Heart, Lymph Node, Prostate, Tonsil

Publications for Commensal Bacterial Infectious Disease

Variations for Commensal Bacterial Infectious Disease

Expression for Commensal Bacterial Infectious Disease

Search GEO for disease gene expression data for Commensal Bacterial Infectious Disease.

Pathways for Commensal Bacterial Infectious Disease

Pathways related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 35)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.55 IL10 IL1B IL2 IL6 TNF
2
Show member pathways
12.54 IL10 IL1B IL2 IL6 TNF
3
Show member pathways
12.49 IL10 IL1B IL2 IL6 TNF
4
Show member pathways
12.27 IL1B IL2 IL6 SELENOO TNF
5
Show member pathways
12.22 IL10 IL1B IL2 IL6 TNF
6 12.2 IL10 IL1B IL6 TNF
7 12.14 IL10 IL1B IL6 TNF
8
Show member pathways
12.11 IL10 IL1B IL2 IL6 TNF
9 11.97 IL1B IL2 IL6 TNF
10 11.94 IL10 IL2 IL6 TNF
11 11.93 IL10 IL1B IL6 TNF
12
Show member pathways
11.88 IL10 IL1B IL2 IL6 TNF
13 11.84 IL1B IL6 TNF
14 11.83 IL1B IL6 TNF
15 11.83 IL10 IL1B IL6 TNF
16 11.79 IL1B IL6 TNF
17 11.73 IL10 IL1B IL2 TNF
18 11.69 IL10 IL1B IL6 TNF
19 11.63 IL1B IL6 TNF
20 11.56 IL1B IL6 TNF
21
Show member pathways
11.56 IL1B IL2 IL6 TNF
22 11.52 IL2 IL6 TNF
23 11.49 IL1B IL2 TNF
24 11.45 IL1B IL6 TNF
25 11.42 IL10 IL1B IL6 TNF
26 11.42 IL10 IL1B IL2 IL6 TNF
27 11.4 IL10 IL1B IL6 TNF
28 11.28 IL1B IL6 TNF
29 11.25 IL1B IL6 TNF
30 11.2 IL10 IL1B IL2 IL6 TNF
31 11.19 IL10 IL1B IL6 TNF
32 11.12 IL10 IL1B IL2 IL6 TNF
33 11.1 IL10 IL1B IL6 TNF
34 10.96 IL10 IL1B IL2 IL6 TNF
35 10.48 IL10 IL1B IL2 IL6 TNF

GO Terms for Commensal Bacterial Infectious Disease

Biological processes related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

(show all 28)
# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.95 EPHX2 IL10 IL1B IL6 TNF
2 positive regulation of protein phosphorylation GO:0001934 9.87 EDNRB IL1B IL2 TNF
3 cytokine-mediated signaling pathway GO:0019221 9.83 IL10 IL1B IL2 IL6 TNF
4 positive regulation of T cell proliferation GO:0042102 9.77 IL1B IL2 IL6
5 positive regulation of interleukin-6 production GO:0032755 9.76 IL1B IL6 TNF
6 positive regulation of DNA-binding transcription factor activity GO:0051091 9.71 IL10 IL1B IL6 TNF
7 positive regulation of interferon-gamma production GO:0032729 9.7 IL1B IL2 TNF
8 negative regulation of growth of symbiont in host GO:0044130 9.64 IL10 TNF
9 positive regulation of immunoglobulin secretion GO:0051024 9.63 IL2 IL6
10 negative regulation of lipid storage GO:0010888 9.62 IL6 TNF
11 endothelial cell apoptotic process GO:0072577 9.61 IL10 TNF
12 positive regulation of chemokine biosynthetic process GO:0045080 9.6 IL1B TNF
13 regulation of establishment of endothelial barrier GO:1903140 9.58 IL1B TNF
14 negative regulation of cytokine secretion involved in immune response GO:0002740 9.56 IL10 TNF
15 positive regulation of fever generation GO:0031622 9.54 IL1B TNF
16 negative regulation of neurogenesis GO:0050768 9.54 IL1B IL6 TNF
17 positive regulation of glial cell proliferation GO:0060252 9.5 IL1B IL6 TNF
18 sequestering of triglyceride GO:0030730 9.49 IL1B TNF
19 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.48 IL1B TNF
20 receptor biosynthetic process GO:0032800 9.46 IL10 TNF
21 response to glucocorticoid GO:0051384 9.43 IL10 IL6 TNF
22 cellular response to lipopolysaccharide GO:0071222 9.35 EDNRB IL10 IL1B IL6 TNF
23 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.33 IL10 IL1B TNF
24 chronic inflammatory response to antigenic stimulus GO:0002439 9.21 TNF
25 positive regulation of neuroinflammatory response GO:0150078 8.8 IL1B IL6 TNF
26 immune response GO:0006955 10.03 IL10 IL1B IL2 IL6 TNF
27 regulation of signaling receptor activity GO:0010469 10.02 IL10 IL1B IL2 IL6 TNF
28 negative regulation of cell proliferation GO:0008285 10.01 DPT GTPBP4 IL10 IL1B IL6

Molecular functions related to Commensal Bacterial Infectious Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 IL10 IL1B IL2 IL6 TNF
2 toxic substance binding GO:0015643 8.96 DSG1 EPHX2

Sources for Commensal Bacterial Infectious Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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