MCID: CMM007
MIFTS: 21

Common Bile Duct Disease

Categories: Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Common Bile Duct Disease

MalaCards integrated aliases for Common Bile Duct Disease:

Name: Common Bile Duct Disease 12 15
Common Bile Duct Diseases 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4137
MeSH 44 D003137
UMLS 73 C0009440

Summaries for Common Bile Duct Disease

MalaCards based summary : Common Bile Duct Disease, also known as common bile duct diseases, is related to bile duct disease and cecal disease. An important gene associated with Common Bile Duct Disease is STK10 (Serine/Threonine Kinase 10). The drugs Pinaverium and Morphine have been mentioned in the context of this disorder. Affiliated tissues include liver.

Wikipedia : 76 The common bile duct, sometimes abbreviated CBD, is a duct in the gastrointestinal tract of organisms... more...

Related Diseases for Common Bile Duct Disease

Diseases in the Bile Duct Disease family:

Common Bile Duct Disease

Diseases related to Common Bile Duct Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 bile duct disease 30.3 CCK GGT2
2 cecal disease 10.1 NODAL STK10
3 postcholecystectomy syndrome 10.0 CCK SOBP
4 cholecystolithiasis 10.0 CCK STK10
5 choledocholithiasis 10.0 CTSC SOBP STK10
6 biliary dyskinesia 10.0 CCK SOBP STK10
7 biliary tract disease 9.9 CCK GGT2
8 megalencephaly 9.9 CCK MLC1
9 gallbladder disease 9.9 CCK NODAL

Graphical network of the top 20 diseases related to Common Bile Duct Disease:



Diseases related to Common Bile Duct Disease

Symptoms & Phenotypes for Common Bile Duct Disease

Drugs & Therapeutics for Common Bile Duct Disease

Drugs for Common Bile Duct Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 71)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Pinaverium Approved Phase 4 59995-65-2
2
Morphine Approved, Investigational Phase 4 57-27-2 5288826
3
Secretin Approved Phase 4 108153-74-8
4
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
5
Meperidine Approved Phase 4,Not Applicable 57-42-1 4058
6
Midazolam Approved, Illicit Phase 4,Not Applicable 59467-70-8 4192
7
Etomidate Approved Phase 4 33125-97-2 667484 36339
8 Anticonvulsants Phase 4
9 Autonomic Agents Phase 4
10 Parasympatholytics Phase 4
11 Calcium, Dietary Phase 4
12 calcium channel blockers Phase 4
13 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
14 Bromides Phase 4
15 Analgesics Phase 4,Phase 3,Phase 2
16 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
17 Central Nervous System Depressants Phase 4,Phase 2
18 Tranquilizing Agents Phase 4,Phase 2
19 Psychotropic Drugs Phase 4,Phase 3,Phase 2
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
21 Cholinesterase Inhibitors Phase 4
22 Cholinergic Agents Phase 4
23 Analgesics, Opioid Phase 4
24 Hormone Antagonists Phase 4
25 Narcotics Phase 4
26 Hormones Phase 4
27 Gastrointestinal Agents Phase 4
28 Anti-Anxiety Agents Phase 4
29 Anesthetics Phase 4,Not Applicable
30 GABA Modulators Phase 4
31 Adjuvants, Anesthesia Phase 4
32 GABA Agents Phase 4
33 Anesthetics, Intravenous Phase 4
34 Hypnotics and Sedatives Phase 4
35 Anesthetics, General Phase 4
36
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
37
Norepinephrine Approved Phase 3 51-41-2 439260
38
Diclofenac Approved, Vet_approved Phase 2, Phase 3 15307-86-5 3033
39 Neurotransmitter Uptake Inhibitors Phase 3,Phase 2
40 Antidepressive Agents Phase 3,Phase 2
41 Analgesics, Non-Narcotic Phase 2, Phase 3
42 Dopamine Agents Phase 3
43 Serotonin and Noradrenaline Reuptake Inhibitors Phase 3
44 Duloxetine Hydrochloride Phase 3
45 Cyclooxygenase Inhibitors Phase 2, Phase 3
46 Anti-Inflammatory Agents Phase 2, Phase 3
47 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3
48 Antirheumatic Agents Phase 2, Phase 3
49
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
50
Amitriptyline Approved Phase 2 50-48-6 2160

Interventional clinical trials:

(show top 50) (show all 53)
# Name Status NCT ID Phase Drugs
1 Pinaverium Bromide in Post-cholecystectomy Sphincter of Oddi Dysfunction Unknown status NCT02833103 Phase 4 Danshu Capsules;Pinaverium Bromide
2 Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla Unknown status NCT02703077 Phase 4
3 A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers Completed NCT01134848 Phase 4 Morphine;Neostigmine;0.9% saline;Secretin;0.9% saline
4 Etomidate vs. Midazolam for Sedation During ERCP Completed NCT02027311 Phase 4 Etomidate;Midazolam;Meperidine
5 Digital SpyGlass Confirmed Common Bile Duct Stones Clearance Without Fluoroscopy Completed NCT02967926 Phase 3
6 Duloxetine in Patients With Suspected Functional Pancreatic/Biliary Pain (Sphincter of Oddi Dysfunction) Completed NCT00471315 Phase 3 Duloxetine
7 Comparison of Endoscopic Sphincterotomy Plus Large-balloon Dilatation and Conventional Treatment for Large CBD Stones Completed NCT02592811 Phase 3
8 Diclofenac for Prevention of Post-ERC Pancreatitis Not yet recruiting NCT03595150 Phase 2, Phase 3 Diclofenac
9 Trial of Laparoscopic Cholecystectomy vs. Non-operative Treatment for Gallbladder Dyskinesia Unknown status NCT02195115 Phase 2 amitriptyline
10 Transvaginal Cholecystectomy Using Endoscopic Assistance Withdrawn NCT00815438 Phase 1
11 A Comparison of Bile Duct Injuries Following Open Cholecystectomy Versus Laparoscopic Cholecystectomy Unknown status NCT00840138
12 Direct Peroral Cholangioscopy by Using an Ultra-slim Upper Endoscope Unknown status NCT02276157
13 The Clinical Characteristics of the Patients With Choledocholithiasis Without Cholangitis Unknown status NCT02647593
14 Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration Unknown status NCT02461147
15 A Prospective Randomized Study Comparing Different Dilation Durations for Endoscopic Papillary Balloon Dilatation Unknown status NCT00451581 Not Applicable
16 Comparison of Papillary Balloon Dilatation Vs.Sphincterotomy for Lithotripsy in Difficult Sphincterotomy or Distal CBD Tapering Unknown status NCT00329888
17 Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography). Unknown status NCT01414400 Not Applicable
18 Laparoendoscopic Rendez Vous Versus Standard Two Stage Approach for the Management of Cholelithiasis/Choledocholithiasis Unknown status NCT00416234 Not Applicable
19 Prospective Evaluation of the Ability of Spyglass Cholangioscopy to Facilitate Radiation Free ERCP Completed NCT03074201 Not Applicable
20 EUS Guided ERCP in Bile Duct Stone Removal Completed NCT02870686 Not Applicable
21 Left Lateral Position and Prone Position for Endoscopic Retrograde Cholangiopancreatography Completed NCT02594475 Not Applicable
22 Laser Versus Mechanical Lithotripsy of Bile Duct Stones Completed NCT01759979 Not Applicable
23 Primary Needle Knife Fistulotomy Versus Conventional Cannulation Method Completed NCT02916199 Not Applicable
24 Study of Endoscopic Sphincterotomy With Needle Knife Papillotome in Patients of Ampullary Impacted Stone Completed NCT00173368
25 Evaluating Predictors & Interventions in Sphincter of Oddi Dysfunction Completed NCT00688662 Not Applicable
26 Laryngeal Mask Airway Supreme Versus the Tracheal Tube as an Airway Device in Elective Laparoscopic Cholecystectomy Completed NCT02037958 Not Applicable
27 Prospective Multicenter Evaluation of a New Short-access-cholangioscope for Biliary Duct Strictures and Gall Stones Completed NCT01683240 Not Applicable
28 Loop-tipped Guidewire in Selective Biliary Cannulation Completed NCT02028845 Not Applicable
29 Trial Comparing Pain in Single-incision Laparoscopic Cholecystectomy Versus Conventional Laparoscopic Cholecystectomy Completed NCT01824186 Not Applicable
30 Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBD Completed NCT01673269 Not Applicable
31 Natural Orifice Translumenal Endoscopic Surgery (NOTES) Transvaginal Cholecystectomy Completed NCT00984100 Not Applicable
32 Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Cholecystectomy Completed NCT00981604 Not Applicable
33 Assessment of Cholangio-pancreatoscopy for the Diagnosis and the Treatment of Biliary and Pancreatic Diseases Recruiting NCT03190343
34 "Endoscopy First" or "Laparoscopic Cholecystectomy First" for Patients With Intermediate Risk of Choledocholithiasis Recruiting NCT03658863 Not Applicable
35 Role of EUS in High Risk of Choledocholithiasis Recruiting NCT03250286 Not Applicable
36 Comparison of LCBDE vs ERCP + LC for Choledocholithiasis Recruiting NCT02515474 Not Applicable
37 The Clinical Evaluation of Oddi Spincteroplasty With Blood Vessel Clamp After Iatrogenic Injury by ERCP Recruiting NCT03795584 Not Applicable
38 The Comparisons of One-stage and Two-stage Stone Removal in Moderate Cholangitis Recruiting NCT03754491 Not Applicable
39 Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCP Recruiting NCT02611453 Not Applicable
40 Microbiomes in Patients of Recurrent Common Bile Duct Stones Recruiting NCT03102281
41 Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient Recruiting NCT02958059 Not Applicable
42 Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders Recruiting NCT01438385
43 Chinese Registry Study on Treatment of Cholecysto-Choledocholithiasis Active, not recruiting NCT02554097
44 Pancreaticoduodenectomy With or Without Preoperative Hyperbaric Oxygen Therapy Enrolling by invitation NCT02575014 Not Applicable Preoperative hyperbaric oxygen
45 Papillary Balloon Dilation Versus Laser Lithotripsy Not yet recruiting NCT03536247 Not Applicable
46 Early MRI in Acute GallstonE Disease Not yet recruiting NCT03709030 Not Applicable
47 Early Precut in Difficult Biliary Cannulation Terminated NCT02596646 Not Applicable
48 Study Investigating the Best Method of Treatment of Bile Duct Stones in Higher Risk Patients Terminated NCT00612846 Not Applicable
49 Evaluation of Gastrointestinal Symptoms and Quality of Life in Patients With Sphincter of Oddi Dysfunction Terminated NCT01410071
50 Single-Incision Laparoscopic Cholecystectomy Versus Traditional Laparoscopic Cholecystectomy Terminated NCT01195285 Not Applicable

Search NIH Clinical Center for Common Bile Duct Disease

Cochrane evidence based reviews: common bile duct diseases

Genetic Tests for Common Bile Duct Disease

Anatomical Context for Common Bile Duct Disease

MalaCards organs/tissues related to Common Bile Duct Disease:

41
Liver

Publications for Common Bile Duct Disease

Articles related to Common Bile Duct Disease:

# Title Authors Year
1
Peroral cholangioscopy--an improved method in the diagnosis of common bile duct diseases. ( 2792678 )
1989
2
Radiomanometry in the diagnosis of common bile duct disease. ( 4445925 )
1974
3
Radiomanometry, flow rates, and cholangiography in the evaluation of common bile duct disease. A study of 220 cases. ( 5058873 )
1972
4
The incidence of common bile duct disease following surgical exploration. ( 14352652 )
1955

Variations for Common Bile Duct Disease

Expression for Common Bile Duct Disease

Search GEO for disease gene expression data for Common Bile Duct Disease.

Pathways for Common Bile Duct Disease

GO Terms for Common Bile Duct Disease

Sources for Common Bile Duct Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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