MCID: CMM007
MIFTS: 27

Common Bile Duct Disease

Categories: Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Common Bile Duct Disease

MalaCards integrated aliases for Common Bile Duct Disease:

Name: Common Bile Duct Disease 12 15
Common Bile Duct Diseases 44 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4137
MeSH 44 D003137
UMLS 70 C0009440

Summaries for Common Bile Duct Disease

MalaCards based summary : Common Bile Duct Disease, also known as common bile duct diseases, is related to obstructive jaundice and cholecystitis. An important gene associated with Common Bile Duct Disease is GPT (Glutamic--Pyruvic Transaminase), and among its related pathways/superpathways are FOXA2 and FOXA3 transcription factor networks and Farnesoid X Receptor Pathway. The drugs Diclofenac and Analgesics, Non-Narcotic have been mentioned in the context of this disorder.

Wikipedia : 73 The common bile duct, sometimes abbreviated CBD, is a duct in the gastrointestinal tract of organisms... more...

Related Diseases for Common Bile Duct Disease

Diseases in the Bile Duct Disease family:

Common Bile Duct Disease

Diseases related to Common Bile Duct Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 296)
# Related Disease Score Top Affiliating Genes
1 obstructive jaundice 30.2 GPT F2 CRP ALB
2 cholecystitis 29.8 GPT F2 CCK ALB ABCB4
3 bile duct disease 28.2 MIR222 GPT F2 CRP CEACAM5 CCK
4 uvulitis 10.4 GPT CRP
5 gummatous syphilis 10.4 GPT CRP
6 viral laryngitis 10.4 GPT CRP
7 intestinal tuberculosis 10.4 CRP ALB
8 tinea unguium 10.4 GPT CRP
9 external ear carcinoma 10.4 CRP CEACAM5
10 dipetalonemiasis 10.4 GPT ALB
11 chronic duodenal ileus 10.4 CRP ALB
12 heterophyiasis 10.4 GPT ALB
13 afferent loop syndrome 10.4 GPT ALB
14 pericardial tuberculosis 10.4 CRP CEACAM5
15 orbital osteomyelitis 10.4 F2 CRP
16 hepatoportal sclerosis 10.4 GPT F2
17 achenbach syndrome 10.4 F2 CRP
18 small intestine diverticulitis 10.4 F2 CRP
19 peptic ulcer perforation 10.4 CRP ALB
20 pyridoxine deficiency anemia 10.4 GPT F2
21 renal pelvis squamous cell carcinoma 10.4 F2 CRP
22 ankylosing spondylitis 3 10.4 CRP ALB
23 synovial angioma 10.3 F2 CRP
24 chronic intestinal vascular insufficiency 10.3 CRP ALB
25 cavernous sinus thrombosis 10.3 F2 CRP
26 subdural empyema 10.3 F2 CRP
27 lemierre's syndrome 10.3 F2 CRP
28 meningovascular neurosyphilis 10.3 CRP ALB
29 internal hemorrhoid 10.3 F2 CRP
30 lymphangitis 10.3 CRP CEACAM5
31 acute cor pulmonale 10.3 F2 CRP
32 intracranial sinus thrombosis 10.3 F2 CRP
33 aspiration pneumonitis 10.3 CRP ALB
34 hemopericardium 10.3 F2 CRP
35 inflammatory and toxic neuropathy 10.3 CRP ALB
36 abducens nerve disease 10.3 F2 CRP
37 non-a-e hepatitis 10.3 F2 ALB
38 antipyrine metabolism 10.3 F2 ALB
39 cholesterol embolism 10.3 F2 CRP
40 early congenital syphilis 10.3 F2 CRP
41 bacterial conjunctivitis 10.3 CRP ALB
42 generalized atherosclerosis 10.3 CRP ALB
43 benign essential hypertension 10.3 CRP ALB
44 suppurative cholangitis 10.3 GPT CRP ABCB4
45 cauda equina syndrome 10.3 F2 CRP
46 large intestine lipoma 10.3 GPT CRP CEACAM5
47 lipoma of colon 10.3 GPT CRP CEACAM5
48 duodenum adenoma 10.3 GPT CRP CEACAM5
49 toxic megacolon 10.3 CRP ALB
50 branch retinal artery occlusion 10.3 F2 CRP

Graphical network of the top 20 diseases related to Common Bile Duct Disease:



Diseases related to Common Bile Duct Disease

Symptoms & Phenotypes for Common Bile Duct Disease

Drugs & Therapeutics for Common Bile Duct Disease

Drugs for Common Bile Duct Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Diclofenac Approved, Vet_approved Phase 2, Phase 3 15307-86-5 3033
2 Analgesics, Non-Narcotic Phase 2, Phase 3
3 Analgesics Phase 2, Phase 3
4 Cyclooxygenase Inhibitors Phase 2, Phase 3
5 Antirheumatic Agents Phase 2, Phase 3
6 Anti-Inflammatory Agents Phase 2, Phase 3
7 Anti-Inflammatory Agents, Non-Steroidal Phase 2, Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Digital SpyGlass Cholangioscopy Confirmed Common Bile Duct Stones Clearance Without Fluoroscopy Completed NCT02967926 Phase 3
2 Diclofenac for Prevention of Post-ERC Pancreatitis Not yet recruiting NCT03595150 Phase 2, Phase 3 Diclofenac
3 Assessment of Cholangio-pancreatoscopy for the Diagnosis and the Treatment of Biliary and Pancreatic Diseases Trial " EASYSPY " Unknown status NCT03190343
4 Comparison of Iatrogenic Common Bile Duct Injuries Following Open Cholecystectomy vs Laparoscopic Cholecystectomy Unknown status NCT00840138
5 Double Guidewire Technique Versus Transpancreatic Precut in Patients With Repetitive Unintentional Cannulation of the Pancreatic Duct. Not yet recruiting NCT04503200
6 Early Precut Sphincterotomy During ERCP With Difficult Biliary Access (Italian: Esecuzione Del Pre-cut Precoce in Corso di ERCP Con Difficoltosa Incannulazione Della Via Biliare) Terminated NCT02596646

Search NIH Clinical Center for Common Bile Duct Disease

Cochrane evidence based reviews: common bile duct diseases

Genetic Tests for Common Bile Duct Disease

Anatomical Context for Common Bile Duct Disease

Publications for Common Bile Duct Disease

Articles related to Common Bile Duct Disease:

(show all 23)
# Title Authors PMID Year
1
OPTIMUM DURATION OF PERCUTANEOUS TRANSHEPATIC CHOLANGIODRAINAGE IN COMMON BILE DUCT DISEASES COMPLICATED BY OBSTRUCTIVE JAUNDICE. 61
33148834 2020
2
Effect of p38 mitogen-activate protein kinase on MUC5AC protein expression of bile duct epithelial cells in hepatolithiasis patients. 61
26722604 2015
3
[Percutaneous endoscopic cholangioscopy (percutaneous cholangioscopy)]. 61
15560566 2004
4
[Peroral cholangioscopy]. 61
15332645 2004
5
Endolaparoscopic rendezvous treatment: a satisfying therapeutic choice for cholecystocholedocolithiasis. 61
11972193 2002
6
Percutaneous cholangioscopy in the management of biliary disease: experience in 25 patients. 61
11232890 2000
7
Endoscopic retrograde cholangiopancreatography in elderly patients. 61
10408661 1998
8
Hepatobiliary disease in cystic fibrosis patients with pancreatic sufficiency. 61
7535738 1995
9
[Choledochoduodenostomy in the treatment of benign disease of the common bile duct: evaluation of long-term results]. 61
7547119 1995
10
[Percutaneous transhepatic cholangioscopy as a single-step technique]. 61
1950035 1991
11
Operative cholangiography. 61
2316802 1990
12
Peroral cholangioscopy--an improved method in the diagnosis of common bile duct diseases. 61
2792678 1989
13
Operative therapy of gallbladder disease in patients with cystic fibrosis. 61
2729516 1989
14
Rigid or flexible choledochoscopy? 61
4065050 1985
15
In vivo measurements of the internal and external diameters of the common bile duct in man. 61
7221849 1981
16
Is intravenous cholangiography still useful? 61
7409384 1980
17
[Biliary lithiasis in patients aged over 70 years: considerations on 125 operations]. 61
7225149 1980
18
The relationship between biliary tract infections and postoperative complications. 61
341378 1978
19
[Diagnosis and surgical management of cholecystitis complicated by common bile duct diseases]. 61
633759 1978
20
Radiomanometry in the diagnosis of common bile duct disease. 61
4445925 1974
21
[Serum enzyme and isoenzyme changes in acute common bile duct diseases]. 61
4144178 1973
22
Radiomanometry, flow rates, and cholangiography in the evaluation of common bile duct disease. A study of 220 cases. 61
5058873 1972
23
The incidence of common bile duct disease following surgical exploration. 61
14352652 1955

Variations for Common Bile Duct Disease

Expression for Common Bile Duct Disease

Search GEO for disease gene expression data for Common Bile Duct Disease.

Pathways for Common Bile Duct Disease

Pathways related to Common Bile Duct Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.44 F2 ALB AFP
2 10.23 ABCB4 ABCB11

GO Terms for Common Bile Duct Disease

Cellular components related to Common Bile Duct Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.76 SPATA20 F2 ERVMER34-1 CRP CEACAM5 CCK
2 extracellular space GO:0005615 9.28 MIRLET7F2 MIR222 GPT F2 CRP CELA3B
3 intercellular canaliculus GO:0046581 8.96 ABCB4 ABCB11

Sources for Common Bile Duct Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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