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MCID: CMM005
MIFTS: 63

Common Cold

Categories: Infectious diseases, Oral diseases, Respiratory diseases, Smell/Taste diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Common Cold

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MalaCards integrated aliases for Common Cold:

Name: Common Cold 12 76 55 43 3 44 15 73
Acute Viral Rhinopharyngitis 12
Nasopharyngitis - Acute 12
Nasopharyngitis, Acute 12
Acute Nasopharyngitis 12
Rhino-Sinusitis 12
Acute Rhinitis 12
Rhinosinusitis 15
Acute Coryza 12
Common Colds 63

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Respiratory diseases Smell/Taste diseases Oral diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:10459
ICD10 33 J00
ICD9CM 35 460
MeSH 44 D003139
SNOMED-CT 68 54150009 82272006
UMLS 73 C0009443
Sources

Summaries for Common Cold

About this section
MedlinePlus : 43 Sneezing, sore throat, a stuffy nose, coughing - everyone knows the symptoms of the common cold. It is probably the most common illness. In the course of a year, people in the United States suffer 1 billion colds. You can get a cold by touching your eyes or nose after you touch surfaces with cold germs on them. You can also inhale the germs. Symptoms usually begin 2 or 3 days after infection and last 2 to 14 days. Washing your hands and staying away from people with colds will help you avoid colds. There is no cure for the common cold. But there are treatments that can make you feel better while you wait for the cold to go away on its own: Getting plenty of rest Drinking fluids Gargling with warm salt water Using cough drops or throat sprays Taking over-the-counter pain or cold medicines However, do not give aspirin to children. And do not give cough medicine to children under four.

MalaCards based summary : Common Cold, also known as acute viral rhinopharyngitis, is related to pulmonary disease, chronic obstructive and viral infectious disease, and has symptoms including fever, pruritus and tinnitus. An important gene associated with Common Cold is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Montelukast and Capsaicin have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and bone, and related phenotypes are Reduced mammosphere formation and hematopoietic system

Disease Ontology : 12 An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus.

CDC : 3 Sore throat and runny nose are usually the first signs of a cold, followed by coughing and sneezing. Most people recover in about 7-10 days. You can help reduce your risk of getting a cold: wash your hands often, avoid close contact with sick people, and don’t touch your face with unwashed hands.

PubMed Health : 63 About common colds: Common colds, or simply “colds,” are usually quite harmless and go away again on their own. Symptoms of a cold such as a cough, sore throat and a runny nose can be really annoying. A severe cold can make you feel weak and ill, too.Colds usually go away on their own after about a week, but some symptoms may last longer. Although a sore throat or a stuffy nose may be gone after just a few days, it can sometimes take up to three weeks for a cough to disappear completely.Treatment with medication usually isn’t necessary. Some medications may, at best, help relieve the symptoms a bit. Because colds are typically caused by viruses, it also doesn't make sense to use antibiotics to treat an ordinary cold. Antibiotics only work against bacteria.

Wikipedia : 76 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

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Related Diseases for Common Cold

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Diseases related to Common Cold via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 252)
# Related Disease Score Top Affiliating Genes
1 pulmonary disease, chronic obstructive 32.0 RNASE3 MUC5AC IL13 CXCL8 CCL5 CCL11
2 viral infectious disease 31.4 CCL5 CXCL8 IFNA2 TLR9
3 sinusitis 30.3 CXCL8 IL5 RNASE3
4 hypereosinophilic syndrome 30.3 RNASE3 IL5 IL13 CCL11
5 cellulitis 30.1 IL1R1 IL5 RNASE3
6 ige responsiveness, atopic 29.9 IL13 IL5 RNASE3
7 bronchitis 29.8 RNASE3 IL5 CXCL8 CCL11 ALB
8 maxillary sinusitis 29.8 SELP RNASE3 CCL5
9 otitis media 29.7 RNASE3 MUC5AC CXCL8 CCL11 ALB
10 allergic rhinitis 29.7 RNASE3 IL5 IL13 ICAM1 CXCL8 CCL11
11 rhinitis 29.6 CCL11 CCL5 CXCL8 ICAM1 IL13 IL5
12 allergic asthma 29.5 CCL11 CCL5 IL13 IL5 RNASE3 TSLP
13 food allergy 29.5 RNASE3 IL5 IL13 ALB
14 dermatitis 29.4 TSLP TLR9 IL5 IL13 CCL11
15 cystic fibrosis 29.2 CXCL8 LPO MUC5AC RNASE3
16 pneumonia 29.2 TLR9 IL5 IL13 CXCL8 CCL5 CCL11
17 esophagitis 29.2 TSLP IL5 IL13 CXCL8 CCL11
18 myocardial infarction 29.0 ALB CCL5 ICAM1 LDLR POSTN SELP
19 bronchiolitis 29.0 CCL11 CCL5 CXCL8 IL13 IL5 RNASE3
20 esophagitis, eosinophilic, 1 28.9 CCL11 IL13 IL5 POSTN TSLP
21 allergic hypersensitivity disease 28.9 CCL11 CCL5 IL13 IL5 RNASE3 TLR9
22 dermatitis, atopic 28.6 CCL11 CCL5 CXCL8 ICAM1 IL13 IL5
23 asthma 28.6 CCL11 CCL5 CXCL8 ICAM1 IL13 IL1R1
24 malaria 28.5 ALB CCL11 CCL5 CXCL8 ICAM1 IL13
25 nasopharyngitis 11.5
26 influenza 11.3
27 otosalpingitis 11.2
28 young syndrome 11.1
29 ciliary dyskinesia, primary, 22 11.1
30 tonsillitis 10.9
31 pertussis 10.9
32 erythema infectiosum 10.9
33 mda5 deficiency 10.9
34 bone inflammation disease 10.3
35 chloramine t respiratory allergy 10.3 ALB RNASE3
36 heterophyiasis 10.2 ALB ICAM1
37 vulvovaginitis 10.2 CXCL8 CCL5 CCL11
38 toxicodendron dermatitis 10.2 CXCL8 ICAM1
39 pemphigoid gestationis 10.2 CCL11 IL5
40 adenoid hypertrophy 10.2
41 st. louis encephalitis 10.2 IFNA2 RNASE3
42 pyoderma 10.2 CXCL8 IFNA2 IL1R1
43 extrinsic allergic alveolitis 10.2 ALB CCL5 CXCL8
44 herpes simplex virus keratitis 10.2 CXCL8 ICAM1
45 folliculitis 10.2 CCL11 CCL5 IL5
46 pyuria 10.2 ALB CXCL8
47 giant papillary conjunctivitis 10.2 RNASE3 CXCL8 CCL11
48 meningoencephalitis 10.2 ALB CCL5 TLR9
49 bagassosis 10.2 CXCL8 IL5
50 loeffler endocarditis 10.2 IL5 RNASE3

Graphical network of the top 20 diseases related to Common Cold:



Diseases related to Common Cold
Sources

Symptoms & Phenotypes for Common Cold

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UMLS symptoms related to Common Cold:


fever, pruritus, tinnitus, rhinorrhea, snoring, coughing, sore throat, vertigo/dizziness, equilibration disorder, catarrh

GenomeRNAi Phenotypes related to Common Cold according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 ALB CXCL8 IL5 LDLR MUC5AC TLR9

MGI Mouse Phenotypes related to Common Cold:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.03 CCL11 CCL5 ICAM1 IL13 IL1R1 IL33
2 digestive/alimentary MP:0005381 9.97 ALB ICAM1 IL13 IL33 IL5 LDLR
3 homeostasis/metabolism MP:0005376 9.97 ALB ICAM1 IL13 IL1R1 IL33 IL5
4 immune system MP:0005387 9.77 CCL11 CCL5 ICAM1 IL13 IL1R1 IL33
5 respiratory system MP:0005388 9.17 CCL11 IL13 IL1R1 IL33 IL5 SELP
Sources

Drugs & Therapeutics for Common Cold

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PubMedHealth treatment related to Common Cold: 63

Because there are so many different cold viruses, there is currently no medicine that can fight all cold viruses and shorten the length of colds. But various medications can relieve some of the symptoms a little. These include painkillers like ibuprofen and acetaminophen (paracetamol), as well as decongestant (anti-swelling) nasal sprays for temporary use.Antibiotics are usually not effective against colds and, because of their possible side effects, should only be used if there are complications. Products that contain zinc, vitamin C, or echinacea extracts are also commonly recommended for the treatment of colds. It's not currently possible to reliably evaluate the advantages and disadvantages of these herbal products because there has been little research in this area, and the studies that have been done have produced contradictory results. Herbal products like extracts taken from Pelargonium (umckaloabo), primrose, thyme, eucalyptus and ivy may possibly be able to relieve a cough somewhat.

Drugs for Common Cold (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 245)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Montelukast Approved Phase 4,Phase 3,Not Applicable 158966-92-8 5281040
2
Capsaicin Approved Phase 4,Phase 2 404-86-4 1548943
3
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
4
Ethanol Approved Phase 4,Not Applicable 64-17-5 702
5
Caffeine Approved Phase 4,Phase 3 58-08-2 2519
6
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1 103-90-2 1983
7
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
8
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
9
Histamine Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 51-45-6, 75614-87-8 774
10
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
11
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
12
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-42-7 6041
13
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1491-59-4 4636
14
Ipratropium Approved Phase 4 60205-81-4, 22254-24-6 43232
15
Dextromethorphan Approved Phase 4,Phase 3,Phase 1 125-71-3 5360696 5362449
16
Thyme Approved Phase 4,Not Applicable
17
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3 55-56-1 2713 9552079
18
Echinacea Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable
19
Oseltamivir Approved Phase 4 204255-11-8, 196618-13-0 65028
20
Azelastine Approved Phase 4,Phase 3 58581-89-8 2267
21 Orange Approved Phase 4,Not Applicable
22
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
23
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Not Applicable 50-81-7 5785 54670067
24
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
25
Maleic acid Experimental Phase 4,Phase 3 110-16-7 444266
26
BCG vaccine Investigational Phase 4
27 Andrographolide Investigational Phase 4,Not Applicable 5508-58-7
28 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Not Applicable
29 Hormone Antagonists Phase 4,Phase 3,Not Applicable
30 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
31 Hormones Phase 4,Phase 3,Not Applicable
32 Leukotriene Antagonists Phase 4,Not Applicable
33 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Not Applicable
34 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
35 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Antipruritics Phase 4,Phase 3,Phase 2,Phase 1
37 Sodium Benzoate Phase 4
38 Antifungal Agents Phase 4
39 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Central Nervous System Stimulants Phase 4,Phase 3,Not Applicable
42 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
43 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 Antipyretics Phase 4,Phase 3,Phase 2,Phase 1
45 Anti-Inflammatory Agents Phase 4,Phase 3,Not Applicable
46 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
47 Anti-Allergic Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Chlorpheniramine, phenylpropanolamine drug combination Phase 4,Phase 3,Phase 2,Phase 1
49 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Histamine H1 Antagonists Phase 4,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 231)
# Name Status NCT ID Phase Drugs
1 A Study of Arbidol (Umifenovir) for Treatment and Prophylaxis of Influenza and Common Cold Unknown status NCT01651663 Phase 4 Arbidol (Umifenovir);Arbidol (Umifenovir)
2 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
3 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
4 Bromelin, a Compound Prepared With Ananas Comocus Extract and Honey, for Acute Cough Unknown status NCT01356693 Phase 4 Bromelin;Placebo
5 Montelukast for Persistent Cough in Young People and Adults Unknown status NCT01279668 Phase 4 Montelukast;Placebo
6 Effects of a Common Cold Treatment on Cognitive Function Completed NCT01466348 Phase 4 Paracetamol and Caffeine;Paracetamol
7 Symptomatic Treatment of Common Cold Symptoms Completed NCT01033526 Phase 4 Aspirin (Acetylsalicylic acid, BAYE4465);Placebo
8 Iota-Carrageenan Nasal Spray in Common Cold Completed NCT01944631 Phase 4
9 Safety Trial of Atrovent® in Pediatric Patients With Rhinorrhea Associated With a Common Cold or Allergy Completed NCT02238210 Phase 4 Atrovent®
10 The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza. Completed NCT02246166 Phase 4 Test tablet
11 Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold Completed NCT01465009 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Placebo
12 Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold Completed NCT00378144 Phase 4 Pseudoephedrine/Paracetamol
13 PEACe: Ivy, Thyme and Cisti Extract (Phytus) Efficacy in Acute Cough Completed NCT02981147 Phase 4 Phytus (Cisti, Thyme and Ivy Leaves)
14 A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies Completed NCT01332578 Phase 4 Paracetamol;Phenylephrine;Ascorbic Acid
15 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction Completed NCT01847131 Phase 4 oxymetazoline;Placebo nasal spray
16 Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections Completed NCT01728090 Phase 4
17 Comparison of Efficacy and Tolerability of Two Cough Syrups in Cough Due to Cold in Children. Completed NCT01968434 Phase 4 carbocisteine cough syrup
18 Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults Completed NCT03154515 Phase 4 Ingavirin;Placebo
19 Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During Colds Completed NCT00189475 Phase 4 Montelukast
20 Efficacy and Safety of Imuneks 10 mg Capsules in the Prophylaxis of Cold Completed NCT02807220 Phase 4 Imuneks 10mg
21 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
22 Echinacea Safety Study Completed NCT01021995 Phase 4 echinacea;placebo
23 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
24 Prevention of RSV Infections in Bone Marrow Transplant Recipients Completed NCT00001903 Phase 4 RSV Polyclonal Immunoglobulin
25 A Study of Oseltamivir (Tamiflu) for the Seasonal Prophylaxis of Influenza in Immunocompromised Participants Completed NCT00412737 Phase 4 Oseltamivir;Placebo
26 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
27 Effect of OM-85 BV on Wheezing Related Morbidity in Children With Recurrent Wheezing Completed NCT00733226 Phase 4 OM-85 BV (Broncho-Vaxom);OM-85 BV (placebo)
28 Dextromethorphan Pediatric Acute Cough Study Recruiting NCT02651116 Phase 4 Dextromethorphan Hydrobromide;Placebo
29 Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea Recruiting NCT02630121 Phase 4 Oxymetazoline Hydrochloride;Placebo
30 A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis Recruiting NCT03132610 Phase 4 andrographolide sulfonate;andrographolide sulfonate simulation
31 Evaluate the Efficacy and Safety of Andrographolide Sulfonate in Patients With Acute Tonsillitis Recruiting NCT03134443 Phase 4 Andrographolide sulfonate;Andrographolide sulfonate simulation
32 Immune Response to High-Dose vs. Standard Dose Influenza Vaccine Active, not recruiting NCT02297542 Phase 4
33 Non-specific Effects of Rabies Vaccine Enrolling by invitation NCT03656198 Phase 4 Sterile Water Injection
34 Acute Cough Study In Children Terminated NCT01257542 Phase 4 Dextromethorphan;Placebo
35 Study Of RV-39 In Patients Who Also Have Asthma Terminated NCT00503009 Phase 4 fluticasone propionate/salmeterol;fluticasone propionate;placebo
36 Echinaforce Junior Bioavailability Trial Withdrawn NCT03070314 Phase 4 Echinaforce junior
37 Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold Unknown status NCT02735070 Phase 3 Resfenol;Coristina d
38 Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome Unknown status NCT00940836 Phase 3 Resfenol;Placebo;Co interventional acetaminophen
39 Effectiveness and Safety of the of Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup in Improvement of Symptoms Resulting From Acute Respiratory Infections. Unknown status NCT00857987 Phase 3 EMS Expectorant
40 Mepolizumab Treatment for Rhinovirus-induced Asthma Exacerbations Unknown status NCT01520051 Phase 3 Mepolizumab;Placebo
41 Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants Unknown status NCT01249911 Phase 3
42 Effects of Two Doses of a Common Cold Treatment on Alertness Completed NCT01686646 Phase 3 paracetamol + caffeine;paracetamol
43 Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold Completed NCT00452270 Phase 3 Xylometazoline
44 Evaluation of Efficacy and Safety of Oral Solution Resfenol in Reducing Symptoms of Common Cold And Flu Completed NCT01158326 Phase 3 Resfenol
45 A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold Completed NCT01744106 Phase 3 pseudoephedrine hydrochloride 30 mg tablets;Placebo tablets
46 Echinacea Versus Placebo Effect in Common Cold (Physician Echinacea Placebo) Completed NCT00065715 Phase 3
47 Pomegranate Products for Prevention of Common Cold Completed NCT00617318 Phase 3
48 Efficacy and Safety of Paracetamol, Chlorpheniramine and Phenylephrine in the Treatment of Common Cold and Flu Syndrome Completed NCT01389518 Phase 3 Active;Placebo
49 Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold Completed NCT01361399 Phase 3 Acetylsalicylic acid (Aspirin, BAYE4465) & Lidocain;Acetylsalicylic Acid (Aspirin, BAYE4465);Lidocain;Placebo
50 Safety and Intake Effect of EPs® 7630 (an Extract of the Roots of Pelargonium Sidoides) Completed NCT02174653 Phase 3 EPs® 7630;Placebo

Search NIH Clinical Center for Common Cold

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: common cold

Sources

Genetic Tests for Common Cold

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Sources

Anatomical Context for Common Cold

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MalaCards organs/tissues related to Common Cold:

41
Eye, Testes, Bone, Skin, Bone Marrow, Lung, Heart
Sources

Publications for Common Cold

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Articles related to Common Cold:

(show top 50) (show all 1001)
# Title Authors Year
1
Smoking, leisure-time exercise and frequency of self-reported common cold among the general population in northeastern China: a cross-sectional study. ( 29486739 )
2018
2
Effects of common cold and concomitant administration of nasal decongestant on the pharmacokinetics and pharmacodynamics of nasal glucagon in otherwise healthy participants: A randomized clinical trial. ( 29053231 )
2018
3
Randomised controlled trial of rhinothermy for treatment of the common cold: a feasibility study. ( 29593018 )
2018
4
Prenatal exposure to ambient temperature variation increases the risk of common cold in children. ( 29476971 )
2018
5
A potential cure for the common cold. ( 29789723 )
2018
6
Potential common factors associated with predisposition to common cold in middle-aged and elderly Japanese: A community-based cross-sectional study. ( 29768343 )
2018
7
A case series on common cold to severe bronchiolitis and pneumonia in children following human metapneumovirus infection in Sri Lanka. ( 29444701 )
2018
8
Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. ( 29760414 )
2018
9
Diagnostic delay for imported malaria: A case of<i>Plasmodium falciparum</i>malaria misdiagnosed as common cold. ( 29340263 )
2018
10
Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population. ( 29301349 )
2018
11
Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens. ( 29111214 )
2018
12
Eunkyosan for treatment of the common cold: A protocol for the systematic review of controlled trials. ( 29718842 )
2018
13
"With fever it's the real flu I would say": laypersons' perception of common cold and influenza and their differences - a qualitative study in Austria, Belgium and Croatia. ( 30541479 )
2018
14
Soshiho-tang for treating common cold in children younger than 12 years: A systematic review and meta-analysis of randomized controlled trials. ( 30407301 )
2018
15
What are the effects of vitamin C on the duration and severity of the common cold? ( 30339136 )
2018
16
What treatments are effective for common cold in adults and children? ( 30305295 )
2018
17
Effects of orally administered lactoferrin and lactoperoxidase on symptoms of the common cold. ( 30202407 )
2018
18
Does vitamin C prevent the common cold? ( 30113569 )
2018
19
Eunkyosan for treatment of the common cold: A protocol for the systematic review of controlled trials: Erratum. ( 30113505 )
2018
20
Effects of paraprobiotic Lactobacillus paracasei MCC1849 supplementation on symptoms of the common cold and mood states in healthy adults. ( 30099891 )
2018
21
Antibiotic use in the management of children with the common cold at a provincial hospital in Papua New Guinea: a point-prevalence study. ( 30079842 )
2018
22
Phenylephrine, a common cold remedy active ingredient, suppresses uterine contractions through cAMP signalling. ( 30076382 )
2018
23
Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials. ( 30069463 )
2018
24
Effect of Tea Catechins on Influenza Infection and the Common Cold with a Focus on Epidemiological/Clinical Studies. ( 30037024 )
2018
25
Acupuncture for common cold: A systematic review and meta-analyze protocol. ( 29517665 )
2018
26
Efficacy and safety of Lian-Ju-Gan-Mao capsules for treating the common cold with wind-heat syndrome: study protocol for a randomized controlled trial. ( 28057058 )
2017
27
Vaccines for the common cold. ( 28516442 )
2017
28
Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold: CHEST Expert Panel Report. ( 28837801 )
2017
29
Common cold among pre-school children in China - associations with ambient PM10 and dampness, mould, cats, dogs, rats and cockroaches in the home environment. ( 28351766 )
2017
30
Offspring of parents who were separated and not speaking to one another have reduced resistance to the common cold as adults. ( 28584098 )
2017
31
Rhinovirus - not just the common cold. ( 28646961 )
2017
32
Duration of the common cold and similar continuous outcomes should be analyzed on the relative scale: a case study of two zinc lozenge trials. ( 28494765 )
2017
33
Reasons for the preference of clinic visits to self-medication by common cold patients in Japan. ( 29264062 )
2017
34
Zinc Acetate Lozenges May Improve the Recovery Rate of Common Cold Patients: An Individual Patient Data Meta-Analysis. ( 28480298 )
2017
35
Trend Of Irrational Medication Among The Students Of Department Of Pharmacy Abbottabad University Of Science And Technology In Common Cold And Flu. ( 28712182 )
2017
36
The Efficacy and Safety of Shen Guo Lao Nian Granule for Common Cold of Qi-Deficiency Syndrome: Study Protocol for a Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase II Clinical Trial. ( 29430253 )
2017
37
Efficacy and safety of Reduqing granules in the treatment of common cold with wind-heat syndrome: a randomized, double-blind, double-dummy, positive-controlled trial. ( 29960290 )
2017
38
MEWDS, Common Cold of the Retina. ( 28540002 )
2017
39
Heated, humidified air for the common cold. ( 28849871 )
2017
40
Efficacy and Tolerability of High-dose Pelargonium Extract in Patients With the Common Cold. ( 29055287 )
2017
41
Is Corticosteroid of No Use for Pediatric Patients with Common Cold Undergoing Anesthesia? A Randomized, Double-Blind, Clinical Trial. ( 28824868 )
2017
42
Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. ( 28515951 )
2017
43
Hopes and challenges for the common cold. ( 28238227 )
2017
44
Propolis nasal spray effectively improves recovery from infectious acute rhinitis and common cold symptoms in children: a pilot study. ( 29254297 )
2017
45
Blood-letting therapy for the common cold: A protocol for a systematic review of controlled trials. ( 29390505 )
2017
46
Soothing Properties of Glycerol in Cough Syrups for Acute Cough Due to Common Cold. ( 28970416 )
2017
47
Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature. ( 27402752 )
2016
48
Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold. ( 26633727 )
2016
49
Knowledge, Attitude And Practice Of Common Cold And Its Management Among Doctors Of Pakistan. ( 28712227 )
2016
50
Common Cold - an Umbrella Term for Acute Infections of Nose, Throat, Larynx and Bronchi. ( 27912214 )
2016
Sources

Variations for Common Cold

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Expression for Common Cold

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Search GEO for disease gene expression data for Common Cold.
Sources

Pathways for Common Cold

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Pathways related to Common Cold according to GeneCards Suite gene sharing:

(show all 32)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 66
Show member pathways
 13.95 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13
2
PEDF Induced Signaling 64
Show member pathways
 13.61 CCL11 CCL5 CXCL8 IFNA2 IL13 IL1R1
3
TGF-Beta Pathway 64
Show member pathways
 13.47 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13
4
Akt Signaling 64
Show member pathways
 13.34 CCL11 CCL5 CXCL8 IL13 IL1R1 IL5
5
Cytokine Signaling in Immune system 66
Show member pathways
 13.22 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13
6
Allograft rejection 1 37
Show member pathways
 12.78 CCL11 CXCL8 ICAM1 IFNA2 IL13 IL5
7
Influenza A 37
Show member pathways
 12.64 CCL5 CXCL8 ICAM1 IFNA2 IL13 IL33
8
JAK-STAT signaling pathway (KEGG) 37
Show member pathways
 12.32 IFNA2 IL13 IL5 TSLP
9
Immune response CCR3 signaling in eosinophils 22
Show member pathways
 12.27 CCL11 CCL5 CXCL8 ICAM1
10
Selenium Micronutrient Network 1
Show member pathways
 12.25 ALB CCL5 ICAM1 LDLR
11
IL-17 Family Signaling Pathways 65
Show member pathways
 12.25 CCL11 CXCL8 IL13 IL5 MUC5AC
12
G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins 22
Show member pathways
 12.15 CCL11 CCL5 CXCL8 ICAM1 IL1R1 TLR9
13
IL-1 Family Signaling Pathways 65
Show member pathways
 12.14 CXCL8 IL1R1 IL33 MUC5AC
14
Bacterial infections in CF airways 22
Show member pathways
 12.11 CCL11 CXCL8 IL1R1 TLR9
15
MAPK Pathway 72
Show member pathways
 11.95 IL13 IL1R1 IL5 TLR9
16
Spinal Cord Injury 1
11.93 CXCL8 ICAM1 IL1R1 SELP
17
Interleukin-4 and 13 signaling 66
11.89 CCL11 CXCL8 ICAM1 IL13
18
Immune response IFN gamma signaling pathway 22
Show member pathways
 11.81 CCL11 CCL5 CXCL8 ICAM1 IL13 IL1R1
19
NF-kappa B signaling pathway 37
11.8 CXCL8 ICAM1 IL1R1
20
Rheumatoid arthritis 37
11.77 CCL5 CXCL8 ICAM1
21
Glucocorticoid receptor regulatory network 1
11.73 CXCL8 ICAM1 IL13 IL5
22
Microglia Activation During Neuroinflammation: Microglia Polarization 65
11.66 CCL11 CCL5 IL13
23
IL4-mediated signaling events 1
11.58 CCL11 IL5 SELP
24
Innate Lymphoid Cell Differentiation Pathways 65
11.46 IL13 IL1R1 IL33 IL5 TSLP
25
Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 1
11.43 CCL11 CXCL8 TSLP
26
Malaria 37
11.42 CXCL8 ICAM1 SELP TLR9
27
Th2 Differentiation Pathway 65
11.33 CCL11 IL13 IL33 IL5
28
Lung fibrosis 1
11.15 CCL11 CCL5 CXCL8 IL13 IL5
29
Development and heterogeneity of the ILC family 1
11.13 IL13 IL33 IL5 TSLP
30
G-protein signaling_RhoB regulation pathway 22
11.11 CCL11 CCL5 CXCL8 IL13 IL5
31
G-protein signaling_Rap2B regulation pathway 22
10.94 CCL11 CCL5 CXCL8 IL13 IL5
32
Interleukin-10 signaling 66
10.71 CCL5 CXCL8 ICAM1 IL13 IL1R1
Sources

GO Terms for Common Cold

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Cellular components related to Common Cold according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.83 ALB CCL11 CCL5 CXCL8 IFNA2 IL13
2 external side of plasma membrane GO:0009897 9.55 ICAM1 IL13 IL1R1 LDLR SELP
3 extracellular space GO:0005615 9.53 ALB CCL11 CCL5 CXCL8 ICAM1 IFNA2
4 endolysosome membrane GO:0036020 9.26 LDLR TLR9

Biological processes related to Common Cold according to GeneCards Suite gene sharing:

(show all 24)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.87 CCL11 CCL5 CXCL8 IL13 IL1R1 IL5
2 cellular response to interferon-gamma GO:0071346 9.79 CCL11 CCL5 ICAM1
3 defense response to Gram-negative bacterium GO:0050829 9.77 RNASE3 SELP TLR9
4 regulation of signaling receptor activity GO:0010469 9.76 CCL11 CCL5 CXCL8 IFNA2 IL13 IL33
5 neutrophil chemotaxis GO:0030593 9.75 CCL11 CCL5 CXCL8
6 chemokine-mediated signaling pathway GO:0070098 9.73 CCL11 CCL5 CXCL8
7 cellular response to interleukin-1 GO:0071347 9.73 CCL11 CCL5 CXCL8 ICAM1
8 positive regulation of inflammatory response GO:0050729 9.71 IL33 LDLR TLR9 TSLP
9 positive regulation of interleukin-6 production GO:0032755 9.69 IL33 TLR9 TSLP
10 positive regulation of B cell proliferation GO:0030890 9.67 IL13 IL5 TLR9
11 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.67 CCL5 IFNA2 IL13 TSLP
12 cellular response to fibroblast growth factor stimulus GO:0044344 9.65 CCL5 CXCL8 POSTN
13 cellular response to tumor necrosis factor GO:0071356 9.65 CCL11 CCL5 CXCL8 ICAM1 POSTN
14 leukocyte cell-cell adhesion GO:0007159 9.63 CCL5 ICAM1 SELP
15 positive regulation of macrophage activation GO:0043032 9.62 IL13 IL33
16 negative regulation of G protein-coupled receptor signaling pathway GO:0045744 9.61 CCL5 CXCL8
17 positive regulation of immunoglobulin secretion GO:0051024 9.59 IL33 IL5
18 response to molecule of bacterial origin GO:0002237 9.58 CXCL8 TLR9
19 neutrophil activation GO:0042119 9.57 CCL5 CXCL8
20 cytokine-mediated signaling pathway GO:0019221 9.56 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13
21 positive regulation of interleukin-13 production GO:0032736 9.55 IL33 TSLP
22 positive regulation of immunoglobulin production GO:0002639 9.54 IL13 TLR9
23 positive regulation of interleukin-5 production GO:0032754 9.52 IL33 TSLP
24 inflammatory response GO:0006954 9.28 CCL11 CCL5 CXCL8 IFNA2 IL13 IL1R1

Molecular functions related to Common Cold according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CCL11 CCL5 CXCL8
2 low-density lipoprotein particle receptor activity GO:0005041 9.26 LDLR VLDLR
3 cytokine activity GO:0005125 9.23 CCL11 CCL5 CXCL8 IFNA2 IL13 IL33
4 very-low-density lipoprotein particle receptor activity GO:0030229 8.96 LDLR VLDLR
Sources

Sources for Common Cold

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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