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MCID: CMM005
MIFTS: 62

Common Cold

Categories: Infectious diseases, Oral diseases, Respiratory diseases, Smell/Taste diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Common Cold

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MalaCards integrated aliases for Common Cold:

Name: Common Cold 12 77 56 44 45 15 17 74 3
Acute Viral Rhinopharyngitis 12
Nasopharyngitis - Acute 12
Nasopharyngitis, Acute 12
Acute Nasopharyngitis 12
Rhino-Sinusitis 12
Acute Rhinitis 12
Rhinosinusitis 15
Acute Coryza 12

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Respiratory diseases Smell/Taste diseases Oral diseases
See all MalaCards categories (disease lists)
ICD10: 34


External Ids:

Disease Ontology 12 DOID:10459
ICD9CM 36 460
MeSH 45 D003139
SNOMED-CT 69 54150009 82272006
ICD10 34 J00
UMLS 74 C0009443
Sources

Summaries for Common Cold

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MedlinePlus : 44 Sneezing, sore throat, a stuffy nose, coughing - everyone knows the symptoms of the common cold. It is probably the most common illness. In the course of a year, people in the United States suffer 1 billion colds. You can get a cold by touching your eyes or nose after you touch surfaces with cold germs on them. You can also inhale the germs. Symptoms usually begin 2 or 3 days after infection and last 2 to 14 days. Washing your hands and staying away from people with colds will help you avoid colds. There is no cure for the common cold. But there are treatments that can make you feel better while you wait for the cold to go away on its own: Getting plenty of rest Drinking fluids Gargling with warm salt water Using cough drops or throat sprays Taking over-the-counter pain or cold medicines However, do not give aspirin to children. And do not give cough medicine to children under four.

MalaCards based summary : Common Cold, also known as acute viral rhinopharyngitis, is related to pulmonary disease, chronic obstructive and viral infectious disease, and has symptoms including fever, pruritus and tinnitus. An important gene associated with Common Cold is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Montelukast and Capsaicin have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and bone, and related phenotypes are hematopoietic system and digestive/alimentary

Disease Ontology : 12 An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus.

CDC : 3 Sore throat and runny nose are usually the first signs of a cold, followed by coughing and sneezing. Most people recover in about 7-10 days. You can help reduce your risk of getting a cold: wash your hands often, avoid close contact with sick people, and don’t touch your face with unwashed hands.

Wikipedia : 77 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

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Related Diseases for Common Cold

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Diseases related to Common Cold via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 252)
# Related Disease Score Top Affiliating Genes
1 pulmonary disease, chronic obstructive 32.2 CCL11 CCL5 CXCL8 IL13 RNASE3
2 viral infectious disease 31.3 CCL5 CXCL8 IFNA2
3 sinusitis 30.5 CXCL8 IL5 RNASE3
4 cytokine deficiency 30.4 IL13 IL5
5 hypereosinophilic syndrome 30.3 CCL11 IL13 IL5 RNASE3
6 cellulitis 30.3 IL1R1 IL5 RNASE3
7 otitis media 30.1 ALB CCL11 CXCL8 RNASE3
8 ige responsiveness, atopic 30.1 IL13 IL5 RNASE3
9 pyoderma 30.0 CXCL8 IFNA2 IL1R1
10 maxillary sinusitis 29.9 CCL5 RNASE3 SELP
11 bronchitis 29.9 ALB CCL11 CXCL8 IL5 RNASE3
12 rhinitis 29.6 CCL11 CCL5 CXCL8 ICAM1 IL13 IL5
13 allergic rhinitis 29.5 CCL11 CXCL8 ICAM1 IL13 IL5 RNASE3
14 dermatitis 29.5 CCL11 IL13 IL5 TSLP
15 food allergy 29.5 ALB IL13 IL5 RNASE3
16 allergic hypersensitivity disease 29.4 CCL11 CCL5 IL13 IL5 RNASE3 TSLP
17 pneumonia 29.3 CCL11 CCL5 CXCL8 IL13 IL5
18 allergic asthma 29.2 CCL11 CCL5 IL13 IL5 RNASE3 TSLP
19 esophagitis, eosinophilic, 1 29.2 CCL11 IL13 IL5 TSLP
20 myocardial infarction 29.0 ALB CCL5 ICAM1 LDLR POSTN SELP
21 bronchiolitis 29.0 CCL11 CCL5 CXCL8 IL13 IL5 RNASE3
22 esophagitis 29.0 CCL11 CXCL8 IL13 IL5 TSLP
23 dermatitis, atopic 28.5 CCL11 CCL5 CXCL8 ICAM1 IL13 IL5
24 asthma 28.4 CCL11 CCL5 CXCL8 ICAM1 IL13 IL1R1
25 malaria 27.9 ALB CCL11 CCL5 CXCL8 ICAM1 IL13
26 nasopharyngitis 11.5
27 influenza 11.3
28 otosalpingitis 11.2
29 young syndrome 11.1
30 ciliary dyskinesia, primary, 22 11.1
31 tonsillitis 10.9
32 pertussis 10.9
33 mda5 deficiency 10.9
34 papillary conjunctivitis 10.4 CCL11 CXCL8
35 chloramine t respiratory allergy 10.4 ALB RNASE3
36 heterophyiasis 10.4 ALB ICAM1
37 pemphigoid gestationis 10.3 CCL11 IL5
38 st. louis encephalitis 10.3 IFNA2 RNASE3
39 vulvovaginitis 10.3 CCL11 CCL5 CXCL8
40 bone inflammation disease 10.3
41 toxicodendron dermatitis 10.3 CXCL8 ICAM1
42 pyuria 10.3 ALB CXCL8
43 scabies 10.3 CCL11 CXCL8
44 herpes simplex virus keratitis 10.3 CXCL8 ICAM1
45 blepharoconjunctivitis 10.3 CCL11 RNASE3
46 bagassosis 10.3 CXCL8 IL5
47 extrinsic allergic alveolitis 10.3 ALB CCL5 CXCL8
48 loeffler endocarditis 10.3 IL5 RNASE3
49 folliculitis 10.3 CCL11 CCL5 IL5
50 chronic meningitis 10.3 CCL11 IL5

Graphical network of the top 20 diseases related to Common Cold:



Diseases related to Common Cold
Sources

Symptoms & Phenotypes for Common Cold

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UMLS symptoms related to Common Cold:


fever, pruritus, tinnitus, snoring, rhinorrhea, sore throat, coughing, vertigo/dizziness, equilibration disorder, catarrh

MGI Mouse Phenotypes related to Common Cold:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 CCL11 CCL5 ICAM1 IL13 IL1R1 IL33
2 digestive/alimentary MP:0005381 9.8 ALB ICAM1 IL13 IL33 IL5 LDLR
3 immune system MP:0005387 9.7 CCL11 CCL5 ICAM1 IL13 IL1R1 IL33
4 respiratory system MP:0005388 9.17 CCL11 IL13 IL1R1 IL33 IL5 SELP
Sources

Drugs & Therapeutics for Common Cold

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Drugs for Common Cold (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 269)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Montelukast Approved Phase 4,Phase 3,Not Applicable 158966-92-8 5281040
2
Capsaicin Approved Phase 4,Phase 2 404-86-4 1548943
3
Ethanol Approved Phase 4,Not Applicable 64-17-5 702
4
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
5
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1 103-90-2 1983
6
Caffeine Approved Phase 4,Phase 3 58-08-2 2519
7
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
8
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
9
Histamine Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 51-45-6 774
10
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
11
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
12
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-42-7 6041
13
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1491-59-4 4636
14
Ipratropium Approved Phase 4 60205-81-4, 22254-24-6 43232 657309
15
Dextromethorphan Approved Phase 4,Phase 3,Phase 1 125-71-3 5362449 5360696
16
Thyme Approved Phase 4,Not Applicable
17
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3 55-56-1 2713 9552079
18
Echinacea Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable
19
Oseltamivir Approved Phase 4 204255-11-8, 196618-13-0 65028
20
Azelastine Approved Phase 4,Phase 3 58581-89-8 2267
21 Orange Approved Phase 4,Not Applicable
22
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
23
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Not Applicable 50-81-7 5785 54670067
24
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
25 Andrographolide Investigational Phase 4,Not Applicable 5508-58-7
26
SB-649868 Experimental, Investigational Phase 4,Phase 3 110-16-7, 110-17-8 444972
27
BCG vaccine Investigational Phase 4
28 Hormones Phase 4,Phase 3,Phase 2,Not Applicable
29 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Not Applicable
30 Hormone Antagonists Phase 4,Phase 3,Not Applicable
31 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Not Applicable
33 Leukotriene Antagonists Phase 4,Not Applicable
34 Antipruritics Phase 4,Phase 3,Phase 2,Phase 1
35 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Antifungal Agents Phase 4
39 Sodium Benzoate Phase 4
40 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
41 Anti-Inflammatory Agents Phase 4,Phase 3,Not Applicable
42 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
43 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 Andrographis Phase 4,Not Applicable
45 Antiprotozoal Agents Phase 4
46 Antirheumatic Agents Phase 4,Phase 3
47 Platelet Aggregation Inhibitors Phase 4,Phase 3
48 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
49 Antiparasitic Agents Phase 4
50 Antipyretics Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 235)
# Name Status NCT ID Phase Drugs
1 A Study of Arbidol (Umifenovir) for Treatment and Prophylaxis of Influenza and Common Cold Unknown status NCT01651663 Phase 4 Arbidol (Umifenovir);Arbidol (Umifenovir)
2 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
3 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
4 Bromelin, a Compound Prepared With Ananas Comocus Extract and Honey, for Acute Cough Unknown status NCT01356693 Phase 4 Bromelin;Placebo
5 Montelukast for Persistent Cough in Young People and Adults Unknown status NCT01279668 Phase 4 Montelukast;Placebo
6 A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis Unknown status NCT03132610 Phase 4 andrographolide sulfonate;andrographolide sulfonate simulation
7 Evaluate the Efficacy and Safety of Andrographolide Sulfonate in Patients With Acute Tonsillitis Unknown status NCT03134443 Phase 4 Andrographolide sulfonate;Andrographolide sulfonate simulation
8 Effects of a Common Cold Treatment on Cognitive Function Completed NCT01466348 Phase 4 Paracetamol and Caffeine;Paracetamol
9 Symptomatic Treatment of Common Cold Symptoms Completed NCT01033526 Phase 4 Aspirin (Acetylsalicylic acid, BAYE4465);Placebo
10 Iota-Carrageenan Nasal Spray in Common Cold Completed NCT01944631 Phase 4
11 Safety Trial of Atrovent® in Pediatric Patients With Rhinorrhea Associated With a Common Cold or Allergy Completed NCT02238210 Phase 4 Atrovent®
12 The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza. Completed NCT02246166 Phase 4 Test tablet
13 Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold Completed NCT01465009 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Placebo
14 Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold Completed NCT00378144 Phase 4 Pseudoephedrine/Paracetamol
15 PEACe: Ivy, Thyme and Cisti Extract (Phytus) Efficacy in Acute Cough Completed NCT02981147 Phase 4 Phytus (Cisti, Thyme and Ivy Leaves)
16 A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies Completed NCT01332578 Phase 4 Paracetamol;Phenylephrine;Ascorbic Acid
17 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction Completed NCT01847131 Phase 4 oxymetazoline;Placebo nasal spray
18 Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections Completed NCT01728090 Phase 4
19 Comparison of Efficacy and Tolerability of Two Cough Syrups in Cough Due to Cold in Children. Completed NCT01968434 Phase 4 carbocisteine cough syrup
20 Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults Completed NCT03154515 Phase 4 Ingavirin;Placebo
21 Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During Colds Completed NCT00189475 Phase 4 Montelukast
22 Efficacy and Safety of Imuneks 10 mg Capsules in the Prophylaxis of Cold Completed NCT02807220 Phase 4 Imuneks 10mg
23 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
24 Echinacea Safety Study Completed NCT01021995 Phase 4 echinacea;placebo
25 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
26 Prevention of RSV Infections in Bone Marrow Transplant Recipients Completed NCT00001903 Phase 4 RSV Polyclonal Immunoglobulin
27 A Study of Oseltamivir (Tamiflu) for the Seasonal Prophylaxis of Influenza in Immunocompromised Participants Completed NCT00412737 Phase 4 Oseltamivir;Placebo
28 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
29 Effect of OM-85 BV on Wheezing Related Morbidity in Children With Recurrent Wheezing Completed NCT00733226 Phase 4 OM-85 BV (Broncho-Vaxom);OM-85 BV (placebo)
30 Dextromethorphan Pediatric Acute Cough Study Recruiting NCT02651116 Phase 4 Dextromethorphan Hydrobromide;Placebo
31 Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea Recruiting NCT02630121 Phase 4 Oxymetazoline Hydrochloride;Placebo
32 Immune Response to High-Dose vs. Standard Dose Influenza Vaccine Active, not recruiting NCT02297542 Phase 4
33 Non-specific Effects of Rabies Vaccine Enrolling by invitation NCT03656198 Phase 4 Sterile Water Injection
34 Acute Cough Study In Children Terminated NCT01257542 Phase 4 Dextromethorphan;Placebo
35 Study Of RV-39 In Patients Who Also Have Asthma Terminated NCT00503009 Phase 4 fluticasone propionate/salmeterol;fluticasone propionate;placebo
36 Echinaforce Junior Bioavailability Trial Withdrawn NCT03070314 Phase 4 Echinaforce junior
37 Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold Unknown status NCT02735070 Phase 3 Resfenol;Coristina d
38 Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome Unknown status NCT00940836 Phase 3 Resfenol;Placebo;Co interventional acetaminophen
39 Effectiveness and Safety of the of Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup in Improvement of Symptoms Resulting From Acute Respiratory Infections. Unknown status NCT00857987 Phase 3 EMS Expectorant
40 Mepolizumab Treatment for Rhinovirus-induced Asthma Exacerbations Unknown status NCT01520051 Phase 3 Mepolizumab;Placebo
41 Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants Unknown status NCT01249911 Phase 3
42 Effects of Two Doses of a Common Cold Treatment on Alertness Completed NCT01686646 Phase 3 paracetamol + caffeine;paracetamol
43 Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold Completed NCT00452270 Phase 3 Xylometazoline
44 Evaluation of Efficacy and Safety of Oral Solution Resfenol in Reducing Symptoms of Common Cold And Flu Completed NCT01158326 Phase 3 Resfenol
45 A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold Completed NCT01744106 Phase 3 pseudoephedrine hydrochloride 30 mg tablets;Placebo tablets
46 Echinacea Versus Placebo Effect in Common Cold (Physician Echinacea Placebo) Completed NCT00065715 Phase 3
47 Pomegranate Products for Prevention of Common Cold Completed NCT00617318 Phase 3
48 Efficacy and Safety of Paracetamol, Chlorpheniramine and Phenylephrine in the Treatment of Common Cold and Flu Syndrome Completed NCT01389518 Phase 3 Active;Placebo
49 Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold Completed NCT01361399 Phase 3 Acetylsalicylic acid (Aspirin, BAYE4465) & Lidocain;Acetylsalicylic Acid (Aspirin, BAYE4465);Lidocain;Placebo
50 Safety and Intake Effect of EPs® 7630 (an Extract of the Roots of Pelargonium Sidoides) Completed NCT02174653 Phase 3 EPs® 7630;Placebo

Search NIH Clinical Center for Common Cold

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: common cold

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Genetic Tests for Common Cold

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Anatomical Context for Common Cold

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MalaCards organs/tissues related to Common Cold:

42
Eye, Testes, Bone, Breast, Lung, Bone Marrow, Tonsil
Sources

Publications for Common Cold

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Articles related to Common Cold:

(show top 50) (show all 1155)
# Title Authors Year
1
A pilot, open labelled, randomised controlled trial of hypertonic saline nasal irrigation and gargling for the common cold. ( 30705369 )
2019
2
The Common Cold. ( 30829428 )
2019
3
Antibiotic prescription for under-fives with common cold or upper respiratory tract infection in Savannakhet Province, Lao PDR. ( 30858755 )
2019
4
Smoking, leisure-time exercise and frequency of self-reported common cold among the general population in northeastern China: a cross-sectional study. ( 29486739 )
2018
5
Effects of common cold and concomitant administration of nasal decongestant on the pharmacokinetics and pharmacodynamics of nasal glucagon in otherwise healthy participants: A randomized clinical trial. ( 29053231 )
2018
6
Randomised controlled trial of rhinothermy for treatment of the common cold: a feasibility study. ( 29593018 )
2018
7
Prenatal exposure to ambient temperature variation increases the risk of common cold in children. ( 29476971 )
2018
8
A potential cure for the common cold. ( 29789723 )
2018
9
Potential common factors associated with predisposition to common cold in middle-aged and elderly Japanese: A community-based cross-sectional study. ( 29768343 )
2018
10
A case series on common cold to severe bronchiolitis and pneumonia in children following human metapneumovirus infection in Sri Lanka. ( 29444701 )
2018
11
Acupuncture for common cold: A systematic review and meta-analyze protocol. ( 29517665 )
2018
12
Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. ( 29760414 )
2018
13
Diagnostic delay for imported malaria: A case of<i>Plasmodium falciparum</i>malaria misdiagnosed as common cold. ( 29340263 )
2018
14
Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population. ( 29301349 )
2018
15
Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens. ( 29111214 )
2018
16
Eunkyosan for treatment of the common cold: A protocol for the systematic review of controlled trials. ( 29718842 )
2018
17
Effect of Tea Catechins on Influenza Infection and the Common Cold with a Focus on Epidemiological/Clinical Studies. ( 30037024 )
2018
18
Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials. ( 30069463 )
2018
19
Phenylephrine, a common cold remedy active ingredient, suppresses uterine contractions through cAMP signalling. ( 30076382 )
2018
20
Antibiotic use in the management of children with the common cold at a provincial hospital in Papua New Guinea: a point-prevalence study. ( 30079842 )
2018
21
Effects of paraprobiotic Lactobacillus paracasei MCC1849 supplementation on symptoms of the common cold and mood states in healthy adults. ( 30099891 )
2018
22
Eunkyosan for treatment of the common cold: A protocol for the systematic review of controlled trials: Erratum. ( 30113505 )
2018
23
Does vitamin C prevent the common cold? ( 30113569 )
2018
24
Effects of orally administered lactoferrin and lactoperoxidase on symptoms of the common cold. ( 30202407 )
2018
25
What treatments are effective for common cold in adults and children? ( 30305295 )
2018
26
What are the effects of vitamin C on the duration and severity of the common cold? ( 30339136 )
2018
27
Soshiho-tang for treating common cold in children younger than 12 years: A systematic review and meta-analysis of randomized controlled trials. ( 30407301 )
2018
28
"With fever it's the real flu I would say": laypersons' perception of common cold and influenza and their differences - a qualitative study in Austria, Belgium and Croatia. ( 30541479 )
2018
29
Human Rhinovirus Inhibits Macrophage Phagocytosis of Bacteria in COPD: More than a Common Cold. ( 30571921 )
2018
30
Healthier without healthcare? The paradox of the common cold. ( 30587182 )
2018
31
Efficacy and safety of Lian-Ju-Gan-Mao capsules for treating the common cold with wind-heat syndrome: study protocol for a randomized controlled trial. ( 28057058 )
2017
32
Vaccines for the common cold. ( 28516442 )
2017
33
Soothing Properties of Glycerol in Cough Syrups for Acute Cough Due to Common Cold. ( 28970416 )
2017
34
Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold: CHEST Expert Panel Report. ( 28837801 )
2017
35
Common cold among pre-school children in China - associations with ambient PM10 and dampness, mould, cats, dogs, rats and cockroaches in the home environment. ( 28351766 )
2017
36
Offspring of parents who were separated and not speaking to one another have reduced resistance to the common cold as adults. ( 28584098 )
2017
37
Rhinovirus - not just the common cold. ( 28646961 )
2017
38
Duration of the common cold and similar continuous outcomes should be analyzed on the relative scale: a case study of two zinc lozenge trials. ( 28494765 )
2017
39
Reasons for the preference of clinic visits to self-medication by common cold patients in Japan. ( 29264062 )
2017
40
Zinc Acetate Lozenges May Improve the Recovery Rate of Common Cold Patients: An Individual Patient Data Meta-Analysis. ( 28480298 )
2017
41
Trend Of Irrational Medication Among The Students Of Department Of Pharmacy Abbottabad University Of Science And Technology In Common Cold And Flu. ( 28712182 )
2017
42
The Efficacy and Safety of Shen Guo Lao Nian Granule for Common Cold of Qi-Deficiency Syndrome: Study Protocol for a Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase II Clinical Trial. ( 29430253 )
2017
43
Efficacy and safety of Reduqing granules in the treatment of common cold with wind-heat syndrome: a randomized, double-blind, double-dummy, positive-controlled trial. ( 29960290 )
2017
44
MEWDS, Common Cold of the Retina. ( 28540002 )
2017
45
Heated, humidified air for the common cold. ( 28849871 )
2017
46
Efficacy and Tolerability of High-dose Pelargonium Extract in Patients With the Common Cold. ( 29055287 )
2017
47
Is Corticosteroid of No Use for Pediatric Patients with Common Cold Undergoing Anesthesia? A Randomized, Double-Blind, Clinical Trial. ( 28824868 )
2017
48
Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. ( 28515951 )
2017
49
Hopes and challenges for the common cold. ( 28238227 )
2017
50
Propolis nasal spray effectively improves recovery from infectious acute rhinitis and common cold symptoms in children: a pilot study. ( 29254297 )
2017
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Variations for Common Cold

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Expression for Common Cold

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Search GEO for disease gene expression data for Common Cold.
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Pathways for Common Cold

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Pathways related to Common Cold according to GeneCards Suite gene sharing:

(show all 29)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 67
Show member pathways
 13.95 CCL11 CCL5 CXCL8 ICAM1 ICOSLG IFNA2
2
PEDF Induced Signaling 65
Show member pathways
 13.56 CCL11 CCL5 CXCL8 IFNA2 IL13 IL1R1
3
TGF-Beta Pathway 65
Show member pathways
 13.44 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13
4
Cytokine Signaling in Immune system 67
Show member pathways
 13.2 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13
5
Allograft rejection 1 38
Show member pathways
 12.66 CCL11 CXCL8 ICAM1 ICOSLG IFNA2 IL13
6
Influenza A 38
Show member pathways
 12.45 CCL5 CXCL8 ICAM1 IFNA2 IL13 IL33
7
JAK-STAT signaling pathway (KEGG) 66
Show member pathways
 12.3 IFNA2 IL13 IL5 TSLP
8
Immune response CCR3 signaling in eosinophils 23
Show member pathways
 12.24 CCL11 CCL5 CXCL8 ICAM1
9
Selenium Micronutrient Network 1
Show member pathways
 12.22 ALB CCL5 ICAM1 LDLR
10
IL-17 Family Signaling Pathways 66
Show member pathways
 12.21 CCL11 CXCL8 IL13 IL5
11
G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins 23
Show member pathways
 12.13 CCL11 CCL5 CXCL8 ICAM1 IL1R1
12
Spinal Cord Injury 1
11.9 CXCL8 ICAM1 IL1R1 SELP
13
Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions 66
Show member pathways
 11.88 CCL11 CCL5 CXCL8
14
Interleukin-4 and 13 signaling 67
11.87 CCL11 CXCL8 ICAM1 IL13
15
Immune response IFN gamma signaling pathway 23
Show member pathways
 11.81 CCL11 CCL5 CXCL8 ICAM1 IL13 IL1R1
16
NF-kappa B signaling pathway 38
11.78 CXCL8 ICAM1 IL1R1
17
Rheumatoid arthritis 38
11.75 CCL5 CXCL8 ICAM1
18
Glucocorticoid receptor regulatory network 1
11.69 CXCL8 ICAM1 IL13 IL5
19
Microglia Activation During Neuroinflammation: Microglia Polarization 66
11.62 CCL11 CCL5 IL13
20
IL4-mediated signaling events 1
11.53 CCL11 IL5 SELP
21
Innate Lymphoid Cell Differentiation Pathways 66
11.46 IL13 IL1R1 IL33 IL5 TSLP
22
Malaria 38
11.41 CXCL8 ICAM1 SELP
23
Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway 1
11.38 CCL11 CXCL8 TSLP
24
Th2 Differentiation Pathway 66
11.37 CCL11 IL13 IL33 IL5
25
Development and heterogeneity of the ILC family 1
11.17 IL13 IL33 IL5 TSLP
26
Lung fibrosis 1
11.15 CCL11 CCL5 CXCL8 IL13 IL5
27
G-protein signaling_RhoB regulation pathway 23
11.09 CCL11 CCL5 CXCL8 IL13 IL5
28
G-protein signaling_Rap2B regulation pathway 23
10.92 CCL11 CCL5 CXCL8 IL13 IL5
29
Interleukin-10 signaling 67
10.71 CCL5 CXCL8 ICAM1 IL13 IL1R1
Sources

GO Terms for Common Cold

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Cellular components related to Common Cold according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.77 ALB CCL11 CCL5 CXCL8 IFNA2 IL13
2 external side of plasma membrane GO:0009897 9.63 ICAM1 ICOSLG IL13 IL1R1 LDLR SELP
3 extracellular space GO:0005615 9.5 ALB CCL11 CCL5 CXCL8 ICAM1 IFNA2

Biological processes related to Common Cold according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.91 CCL11 CCL5 CXCL8 IL13 IL1R1 IL5
2 regulation of signaling receptor activity GO:0010469 9.76 CCL11 CCL5 CXCL8 IFNA2 IL13 IL33
3 cellular response to interferon-gamma GO:0071346 9.75 CCL11 CCL5 ICAM1
4 neutrophil chemotaxis GO:0030593 9.72 CCL11 CCL5 CXCL8
5 positive regulation of inflammatory response GO:0050729 9.7 IL33 LDLR TSLP
6 chemokine-mediated signaling pathway GO:0070098 9.69 CCL11 CCL5 CXCL8
7 cellular response to interleukin-1 GO:0071347 9.67 CCL11 CCL5 CXCL8 ICAM1
8 cellular response to tumor necrosis factor GO:0071356 9.65 CCL11 CCL5 CXCL8 ICAM1 POSTN
9 cellular response to fibroblast growth factor stimulus GO:0044344 9.63 CCL5 CXCL8 POSTN
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.62 CCL5 IFNA2 IL13 TSLP
11 positive regulation of smooth muscle cell migration GO:0014911 9.59 CCL5 POSTN
12 positive regulation of macrophage activation GO:0043032 9.58 IL13 IL33
13 leukocyte cell-cell adhesion GO:0007159 9.58 CCL5 ICAM1 SELP
14 negative regulation of G protein-coupled receptor signaling pathway GO:0045744 9.57 CCL5 CXCL8
15 positive regulation of immunoglobulin secretion GO:0051024 9.56 IL33 IL5
16 inflammatory response GO:0006954 9.56 CCL11 CCL5 CXCL8 IFNA2 IL13 IL1R1
17 neutrophil activation GO:0042119 9.54 CCL5 CXCL8
18 positive regulation of interleukin-13 production GO:0032736 9.49 IL33 TSLP
19 positive regulation of interleukin-5 production GO:0032754 9.48 IL33 TSLP
20 cytokine-mediated signaling pathway GO:0019221 9.23 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13

Molecular functions related to Common Cold according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CCL11 CCL5 CXCL8
2 low-density lipoprotein particle receptor activity GO:0005041 9.26 LDLR VLDLR
3 cytokine activity GO:0005125 9.23 CCL11 CCL5 CXCL8 IFNA2 IL13 IL33
4 very-low-density lipoprotein particle receptor activity GO:0030229 8.96 LDLR VLDLR
Sources

Sources for Common Cold

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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