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MCID: CMM005
MIFTS: 57

Common Cold

Categories: Infectious diseases, Oral diseases, Respiratory diseases, Smell/Taste diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Common Cold

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MalaCards integrated aliases for Common Cold:

Name: Common Cold 12 74 54 42 3 43 15 17 71
Acute Viral Rhinopharyngitis 12
Nasopharyngitis - Acute 12
Nasopharyngitis, Acute 12
Acute Nasopharyngitis 12
Rhino-Sinusitis 12
Acute Rhinitis 12
Rhinosinusitis 15
Acute Coryza 12
Common Colds 62

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Respiratory diseases Smell/Taste diseases Oral diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:10459
ICD9CM 34 460
MeSH 43 D003139
NCIt 49 C78599
SNOMED-CT 67 82272006
ICD10 32 J00
UMLS 71 C0009443
Sources

Summaries for Common Cold

About this section
MedlinePlus : 42 Sneezing, sore throat, a stuffy nose, coughing - everyone knows the symptoms of the common cold. It is probably the most common illness. In the course of a year, people in the United States suffer 1 billion colds. You can get a cold by touching your eyes or nose after you touch surfaces with cold germs on them. You can also inhale the germs. Symptoms usually begin 2 or 3 days after infection and last 2 to 14 days. Washing your hands and staying away from people with colds will help you avoid colds. There is no cure for the common cold. But there are treatments that can make you feel better while you wait for the cold to go away on its own: Getting plenty of rest Drinking fluids Gargling with warm salt water Using cough drops or throat sprays Taking over-the-counter pain or cold medicines However, do not give aspirin to children. And do not give cough medicine to children under four.

MalaCards based summary : Common Cold, also known as acute viral rhinopharyngitis, is related to churg-strauss syndrome and pulmonary disease, chronic obstructive, and has symptoms including fever, pruritus and tinnitus. An important gene associated with Common Cold is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Cefditoren and Dexamethasone acetate have been mentioned in the context of this disorder. Affiliated tissues include testes, eye and lung, and related phenotypes are hematopoietic system and digestive/alimentary

Disease Ontology : 12 An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus.

CDC : 3 Sore throat and runny nose are usually the first signs of a cold, followed by coughing and sneezing. Most people recover in about 7-10 days. You can help reduce your risk of getting a cold: wash your hands often, avoid close contact with sick people, and don't touch your face with unwashed hands.

PubMed Health : 62 About common colds: Common colds, or simply “colds,” are usually quite harmless and go away again on their own. Symptoms of a cold such as a cough, sore throat and a runny nose can be really annoying. A severe cold can make you feel weak and ill, too. Colds usually go away on their own after about a week, but some symptoms may last longer. Although a sore throat or a stuffy nose may be gone after just a few days, it can sometimes take up to three weeks for a cough to disappear completely. Treatment with medication usually isn’t necessary. Some medications may, at best, help relieve the symptoms a bit. Because colds are typically caused by viruses, it also doesn't make sense to use antibiotics to treat an ordinary cold. Antibiotics only work against bacteria.

Wikipedia : 74 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

Sources

Related Diseases for Common Cold

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Diseases related to Common Cold via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 685)
# Related Disease Score Top Affiliating Genes
1 churg-strauss syndrome 33.1 RNASE3 IL5 CXCL8 CCL11
2 pulmonary disease, chronic obstructive 32.4 RNASE3 IL5 IL4 IL13 ICOSLG CXCL8
3 viral infectious disease 32.1 IL4 IL13 IFNA2 ICOSLG ICAM1 CXCL8
4 gastroesophageal reflux 31.4 IL5 IL4 CXCL8 CCL11
5 sleep apnea 31.4 SELP ICAM1 CXCL8 ALB
6 bone inflammation disease 31.2 IL4 IL13 ICOSLG CXCL8 CCR6 ALB
7 aspergillosis 31.0 IL5 IL4 IL1R1 CXCL8 CCR6 CCL5
8 bacterial infectious disease 30.9 IL1R1 ICOSLG CXCL8 CCR6
9 dacryoadenitis 30.8 IL4 IL13 ICOSLG CCR6
10 urticaria 30.8 RNASE3 IL5 IL4 IL13
11 acquired immunodeficiency syndrome 30.7 IFNA2 ICAM1 CCR6 ALB
12 igg4-related disease 30.7 IL4 IL33 ICOSLG CCR6
13 vaginitis 30.7 CXCL8 CCR6 CCL5
14 common variable immunodeficiency 30.6 IL5 IL4 IL1R1 ICOSLG
15 exanthem 30.6 ICOSLG CXCL8 CCR6 ALB
16 middle ear disease 30.6 CXCL8 CCR6 ALB
17 food allergy 30.6 RNASE3 IL5 IL4 IL13 CXCL8 ALB
18 immune deficiency disease 30.6 IL4 IL13 ICOSLG CCR6 CCL5
19 diarrhea 30.6 IL5 IL13 IFNA2 CXCL8 ALB
20 chronic fatigue syndrome 30.5 IL5 IL4 IL13 CXCL8 CCL5
21 dermatitis 30.5 TSLP IL5 IL4 IL13 CXCL8 CCR6
22 bronchitis 30.5 RNASE3 IL5 IL4 IL13 CXCL8 CCL5
23 sarcoidosis 1 30.5 SELP IL13 ICOSLG ICAM1 CCR6 CCL5
24 cellulitis 30.5 RNASE3 IL5 IL4 IL1R1 ICOSLG CCR6
25 allergic rhinitis 30.4 RNASE3 IL5 IL4 IL13 ICAM1 CXCL8
26 paranasal sinus disease 30.4 RNASE3 KIDINS220 IL5 IL4 IL13 ICOSLG
27 cytokine deficiency 30.4 IL5 IL13
28 endophthalmitis 30.4 ICAM1 CXCL8 ALB
29 proteasome-associated autoinflammatory syndrome 1 30.4 SELP RNASE3 IL5 IL4 IL1R1 IL13
30 otitis media 30.4 RNASE3 IL5 IL4 IL13 ICAM1 CXCL8
31 pyoderma 30.3 IL1R1 IFNA2 CXCL8 CCR6
32 pyoderma gangrenosum 30.3 IL1R1 IFNA2 CXCL8 CCR6
33 allergic asthma 30.3 TSLP RNASE3 IL5 IL4 IL13 ICAM1
34 pulmonary sarcoidosis 30.3 ICAM1 CCR6 CCL5
35 loeffler syndrome 30.3 IL5 IL33 IL13
36 yellow nail syndrome 30.3 CCR6 ALB
37 keratopathy 30.3 IL4 ICAM1 CXCL8
38 rosacea 30.3 IL33 CXCL8 CCR6
39 maxillary sinusitis 30.3 SELP RNASE3 KIDINS220 CCL5
40 meningoencephalitis 30.3 IL4 CCR6 CCL5 ALB
41 autoimmune disease 30.3 IL5 IL4 IL1R1 IL13 ICOSLG CXCL8
42 rhinitis 30.2 TSLP RNASE3 IL5 IL4 IL33 IL13
43 aphthous stomatitis 30.2 IL5 IL4 CXCL8
44 stomatitis 30.2 LDLR IL4 IFNA2 CXCL8
45 atherosclerosis susceptibility 30.2 SELP LDLR ICAM1 CXCL8 ALB
46 pollen allergy 30.2 RNASE3 IL5 IL13 ICAM1
47 castleman disease 30.2 IL5 IL4 ICAM1 CXCL8
48 osteomyelitis 30.2 IL4 IL13 CXCL8 CCL5
49 neuritis 30.1 IL4 CXCL8 CCL5
50 trichinosis 30.1 TSLP IL5 IL4 IL13

Graphical network of the top 20 diseases related to Common Cold:



Diseases related to Common Cold
Sources

Symptoms & Phenotypes for Common Cold

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UMLS symptoms related to Common Cold:


fever, pruritus, tinnitus, rhinorrhea, snoring, sore throat, coughing, vertigo/dizziness, equilibration disorder, catarrh

MGI Mouse Phenotypes related to Common Cold:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.03 CCL11 CCL5 CCR6 ICAM1 IL13 IL1R1
2 digestive/alimentary MP:0005381 9.97 ALB ICAM1 IL13 IL1R1 IL33 IL4
3 immune system MP:0005387 9.97 ALB CCL11 CCL5 CCR6 ICAM1 IL13
4 integument MP:0010771 9.61 ICAM1 IL13 IL1R1 IL33 IL4 LDLR
5 respiratory system MP:0005388 9.28 CCL11 IL13 IL1R1 IL33 IL4 IL5
Sources

Drugs & Therapeutics for Common Cold

About this section

PubMed Health treatment related to Common Cold: 62

Because there are so many different cold viruses , there is currently no medicine that can fight all cold viruses and shorten the length of colds . But various medications can relieve some of the symptoms a little. These include painkillers like ibuprofen and acetaminophen (paracetamol), as well as decongestant (anti-swelling) nasal sprays for temporary use. Antibiotics are usually not effective against colds and, because of their possible side effects, should only be used if there are complications. Products that contain zinc , vitamin C, or echinacea extracts are also commonly recommended for the treatment of colds. It's not currently possible to reliably evaluate the advantages and disadvantages of these herbal products because there has been little research in this area, and the studies that have been done have produced contradictory results. Herbal products like extracts taken from Pelargonium (umckaloabo), primrose, thyme, eucalyptus and ivy may possibly be able to relieve a cough somewhat.

Drugs for Common Cold (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 372)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cefditoren Approved, Investigational Phase 4 104145-95-1, 117467-28-4 9870843 9571074
2
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
4
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
5
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
6
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
7
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
8 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
9
Thyme Approved Phase 4
10
Caffeine Approved Phase 4 58-08-2 2519
11
Ipratropium Approved, Experimental Phase 4 60205-81-4, 22254-24-6 43232 657309
12
Chlorpheniramine Approved Phase 4 132-22-9, 113-92-8 2725
13
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
14
Budesonide Approved Phase 4 51333-22-3 63006 5281004
15
Capsaicin Approved Phase 4 404-86-4 1548943
16
Almotriptan Approved, Investigational Phase 4 181183-52-8, 154323-57-6 123606
17
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
18
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
19
Sodium citrate Approved, Investigational Phase 4 68-04-2
20
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
21
Racepinephrine Approved Phase 4 329-65-7 838
22
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
23
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
24
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
25
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
26
Prazosin Approved Phase 4 19216-56-9 4893
27
Acetaminophen Approved Phase 4 103-90-2 1983
28
Ibuprofen Approved Phase 4 15687-27-1 3672
29
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
30
Azithromycin Approved Phase 4 83905-01-5 447043 55185
31
Zinc sulfate Approved, Investigational Phase 4 7733-02-0
32
Hydroxychloroquine Approved Phase 4 118-42-3 3652
33
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
34
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
35
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
36
Nitazoxanide Approved, Investigational, Vet_approved Phase 4 55981-09-4 41684
37
Erenumab Approved, Investigational Phase 4 1582205-90-0
38
Salmon calcitonin Approved, Investigational Phase 4 47931-85-1 16129616
39
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
40
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
41
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
42
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
43
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
44
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
45
Polyestradiol phosphate Approved Phase 4 28014-46-2
46
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
47
mometasone furoate Approved, Investigational, Vet_approved Phase 4 83919-23-7
48
Montelukast Approved Phase 4 158966-92-8 5281040
49
Dextromethorphan Approved Phase 4 125-71-3 5360696 5362449
50
Clarithromycin Approved Phase 4 81103-11-9 84029

Interventional clinical trials:

(show top 50) (show all 557)
# Name Status NCT ID Phase Drugs
1 Clinical Relevance of Middle Meatal Bacteriology During Acute Respiratory Infection in Children - Randomised, Double-Blinded Clinical Study Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 Randomized,Double-blind, Placebo Controlled Clinical Trial to Evaluate the Efficacy of the Phytotherapic Compound "Bromelin" on Acute Irritative Cough Unknown status NCT01356693 Phase 4 Bromelin;Placebo
3 A Comparison of Cefditoren Pivoxil 10 mg/kg/Day and Cefditoren Pivoxil 20 mg/kg/Day in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4 cefditoren pivoxil
4 Double-blind, Randomized, Placebo-controlled Clinical Study Investigating Efficacy and Safety of Arbidol (Umifenovir) in Treatment and Prophylaxis of Influenza and Common Cold. Unknown status NCT01651663 Phase 4 Arbidol (Umifenovir);Arbidol (Umifenovir)
5 The Adjunctive Use of a Dexamethasone-Sinufoam Mixture on Endoscopic Sinus Surgery Outcomes: A Randomized, Double-Blind, Placebo-controlled Trial Unknown status NCT01024075 Phase 4 Dexamethasone;Saline
6 The Evaluation of Singulair for the Treatment of Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
7 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery: a 9-month Randomized, Open-label, Controlled Study Unknown status NCT02110654 Phase 4 Montelukast;mometasone furoate nasal spray
8 A Double Blind Randomised Placebo Controlled Trial of Montelukast in the Treatment of Acute Persistent Cough in Young People and Adults in Primary Care Unknown status NCT01279668 Phase 4 Montelukast;Placebo
9 Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children Unknown status NCT00494624 Phase 4 prednisolone
10 PEACe: Ivy, Thyme and Cisti Extract (Phytus) Efficacy in Acute Cough Completed NCT02981147 Phase 4 Phytus (Cisti, Thyme and Ivy Leaves)
11 The HVSI STUDY: High Volume Saline Irrigation in the Post-operative Management of Chronic Rhinosinusitis: A Multicenter Randomized Single-Blind Controlled Trial Completed NCT01575223 Phase 4
12 Effects of a Common Cold Treatment on Cognitive Function Completed NCT01466348 Phase 4 Paracetamol and Caffeine;Paracetamol
13 A Phase IV Safety Trial in Pediatric Patients (Ages 2-5) With Rhinorrhea Associated With a Common Cold or Allergy Completed NCT02238210 Phase 4 Atrovent®
14 Efficacy and Safety of Iota-Carrageenan Nasal Spray 1.2 g/l (0.12 Percent) (Bisolviral) Versus Placebo Nasal Spray in the Early Treatment of Common Cold Completed NCT01944631 Phase 4
15 A Two-arm, Multicenter, Randomized, Double-blind, Single Dose Placebo-controlled Parallel Groups Study Evaluating Efficacy and Tolerability of 800 mg Acetylsalicylic Acid (Aspirina® C) in Adult Patients With a Common Cold During a Two Hour in Patient Phase; and a Follow-up Period of Five Days of Home Treatment as Required Completed NCT01033526 Phase 4 Aspirin (Acetylsalicylic acid, BAYE4465);Placebo
16 Double-blind, Randomized, Placebo-controlled, Single Dose, Parallel Group Study Evaluating Efficacy and Safety of 1000 mg Acetylsalicylic Acid and 1000 mg Paracetamol in Adult Patients With Sore Throat Associated With a Common Cold Completed NCT01465009 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Placebo
17 The Use of Antibiotic Sinonasal Rinse After Sinus Surgery: A Randomized Double-Blind Control Trial Completed NCT02218307 Phase 4 Mupirocin;Placebo
18 Randomised Double Blind Placebo Controlled Multicenter Study for Evaluation of Clinical Efficacy and Safety of Ingavirin 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults. Completed NCT03154515 Phase 4 Ingavirin;Placebo
19 Safety and Efficacy of Long-term Treatment With Echinaforce® Over 4 Months Completed NCT01021995 Phase 4 echinacea;placebo
20 A Double-Blind, Randomised, Placebo-Controlled, Parallelgroup, Single-Dose Study to Evaluate Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza Over a 4 Hour Period Completed NCT02246166 Phase 4 Test tablet
21 Evaluation of Histamine, CGRP and VIP as Biological Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers in Response to "Sinus" Symptoms Completed NCT00208065 Phase 4 almotriptan or pseudoephedrine
22 Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitis - a Randomized, Double Blind, Placebo Controlled Trial Completed NCT03086070 Phase 4 Omeprazole 20mg;Placebo oral capsule
23 A Community Pharmacy Based Investigation in the Self-Medication Area Efficacy and Safety of Sinutab and Pseudoephedrine on Subjects With Nasal Congestion Accompanied by Headache in the Setting of a Common Cold Completed NCT00378144 Phase 4 Pseudoephedrine/Paracetamol
24 Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis Completed NCT03705793 Phase 4 Mometasone Furoate Nasal Irrigation;Mometasone Nasal Spray
25 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis. A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Phase IV Study (Sinusitis Study) Completed NCT02296814 Phase 4 Sinusitis Hevert SL Tablet;Placebo for Sinusitis Hevert SL Tablet
26 A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies Completed NCT01332578 Phase 4 Paracetamol;Phenylephrine;Ascorbic Acid
27 Efficacy and Tolerability of Systemic Methylprednisolone in Children and Adolescents With Chronic Rhinosinusitis Completed NCT01205984 Phase 4 methylprednisolone
28 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4 probiotic containing L.rhamnosus R0011 strain
29 Randomized Clinical Trial to Evaluate Guidelines for Acute Rhinosinusitis (Phase IV Study) Completed NCT00377403 Phase 4 Acetaminophen;Amoxicillin;Dextromethorphan hydrobromide with guaifenesin;Guaifenesin;Pseudoephedrine Sustained Action;Saline spray (0.65%)
30 A Prospective, Multi-Center, Randomized, Controlled, Subject-Blinded Study to Evaluate the Safety and Effectiveness of AdvaCoat Sinus Gel Following Endoscopic Ethmoid Sinus Surgery Completed NCT00554190 Phase 4
31 A Randomized, Double-Blind, Parallel-Group, Multicenter, Placebo-Controlled Study of the Safety and Efficacy of Mucinex D as Adjunct Therapy to Antibiotic Treatment of Acute Respiratory Infection Completed NCT00441246 Phase 4 Mucinex D (600 mg guaifenesin and 60 mg pseudoephedrine HCl extended-release bi-layer tablets)
32 Randomized, Single Blind, Multicenter Study to Evaluate the Efficacy and Tolerability of Syr. Grintuss Pediatric and Syr. Mucolit in Cough Due to Upper Respiratory Tract Infection in Children Completed NCT01968434 Phase 4 carbocisteine cough syrup
33 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Completed NCT02288156 Phase 4 Capsaicin;placebo
34 Azithromycin as add-on Therapy in Patients Failing Medical and Surgical Treatment for Chronic Rhinosinusitis: a Double-blind, Randomized, Placebo-controlled Trial Completed NCT02307825 Phase 4 Azithromycin;Placebo
35 A Proof Of Concept Study to Investigate the Clinical, Histological And Molecular Predictors of Response to Oral and Intranasal Corticosteroid in Nasal Polyposis Completed NCT00788749 Phase 4 Prednisolone;Placebo
36 Spine Patient Outcomes Research Trial (SPORT): A Multicenter Trial for Spinal Stenosis (SpS) Completed NCT00000411 Phase 4
37 Prevention of RSV Infections in Bone Marrow Transplant Recipients Completed NCT00001903 Phase 4 RSV Polyclonal Immunoglobulin
38 The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis Completed NCT02696850 Phase 4 Budesonide;Saline alone
39 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial Completed NCT01919411 Phase 4 Amoxicillin-Potassium Clavulanate;Placebo
40 Clinical Trial for the Assessment of Delayed Antibiotic Treatment Strategies in the Non-complicated Acute Respiratory Tract Infections in General Practice Completed NCT01363531 Phase 4
41 Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections Completed NCT01728090 Phase 4
42 A Randomized Study of Nasal Irrigation Versus Nasal Spray for Chronic Nasal and Sinus Symptoms Completed NCT00318006 Phase 4
43 The Role of Nonspecific Immune Response of the Airway Mucosa in Children With Chronic Rhinosinusitis and Asthma Completed NCT03011632 Phase 4 Mometasone Nasal;placebo mometasone
44 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery: Cocaine Versus Adrenaline Completed NCT01706952 Phase 4 Cocaine;Adrenaline
45 Clinical Trial for the Assessment of Delayed Antibiotic Treatment in the Non-complicated Acute Respiratory Tract Infections in Pediatric (Study DAP-Pediatrics) Completed NCT01800747 Phase 4
46 A Randomized Cohort Trial Evaluating Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4 Doxycycline;Azithromycin;Augmentin
47 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. A Prospective, Randomised, Clinical Trial. Completed NCT01694108 Phase 4
48 Total Intravenous Versus Inhaled Anesthesia in Endoscopic Sinus Surgery for High-Grade Paranasal Disease Completed NCT02578862 Phase 4 Propofol;Sevoflurane
49 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4 Triamcinolone
50 Spine Patient Outcomes Research Trial (SPORT): A Multicenter Randomized Trial for Intervertebral Disc Herniation (IDH) Completed NCT00000410 Phase 4

Search NIH Clinical Center for Common Cold

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Ascorbic Acid
Ascorbic Acid Powder
Echinacea Preparation
Guaifenesin
Phenylpropanolamine
Phenylpropanolamine Hydrochloride
Pseudoephedrine
Pseudoephedrine Hydrochloride
Pseudoephedrine sulfate
Sodium Ascorbate
Zinc Acetate
zinc chloride
Zinc Gluconate
Zinc Sulfate
ZINC SULFATE PWDR

Cochrane evidence based reviews: common cold

Sources

Genetic Tests for Common Cold

About this section
Sources

Anatomical Context for Common Cold

About this section

MalaCards organs/tissues related to Common Cold:

40
Testes, Eye, Lung, T Cells, Skin, Bone, Heart
Sources

Publications for Common Cold

About this section

Articles related to Common Cold:

(show top 50) (show all 3590)
# Title Authors PMID Year
1
Treatment of the Common Cold. 61 42
31478634 2019
2
Treating the Common Cold in Adults. 42 61
31478636 2019
3
Treating the Common Cold in Children. 61 42
31478637 2019
4
Cigarette smoke extract enhances rhinovirus-induced toll-like receptor 3 expression and interleukin-8 secretion in A549 cells. 61 54
19769802 2009
5
Systemic therapy of malignant human melanoma tumors by a common cold-producing enterovirus, coxsackievirus a21. 54 61
14734451 2004
6
The common cold at the turn of the millennium. 54 61
11068660 2000
7
Experimental rhinovirus 16 infection increases intercellular adhesion molecule-1 expression in bronchial epithelium of asthmatics regardless of inhaled steroid treatment. 61 54
10848925 2000
8
Experimental common cold increases mucosal output of eotaxin in atopic individuals. 54 61
10604558 1999
9
Allergen challenge-induced acute exudation of IL-8, ECP and alpha2-macroglobulin in human rhinovirus-induced common colds. 54 61
10836321 1999
10
Association between interleukin-8 concentration in nasal secretions and severity of symptoms of experimental rhinovirus colds. 54 61
9564459 1998
11
Role of nasal interleukin-8 in neutrophil recruitment and activation in children with virus-induced asthma. 54 61
9105080 1997
12
Elevated levels of interleukins IL-1 beta, IL-6 and IL-8 in naturally acquired viral rhinitis. 61 54
7734976 1995
13
Being a front-line dentist during the Covid-19 pandemic: a literature review. 61
32341913 2020
14
Recent progress and challenges in drug development against COVID-19 coronavirus (SARS-CoV-2) - an update on the status. 61
32320825 2020
15
Antiviral activity of furanocoumarins isolated from Angelica dahurica against influenza a viruses H1N1 and H9N2. 61
32389854 2020
16
COVID-19 and anosmia in Tehran, Iran. 61
32344276 2020
17
Correlations in Trends of Sinusitis-Related Online Google Search Queries in the United States. 61
32064888 2020
18
Modeling the impact of mass influenza vaccination and public health interventions on COVID-19 epidemics with limited detection capability. 61
32507746 2020
19
Coronavirus in water environments: Occurrence, persistence and concentration methods - A scoping review. 61
32361598 2020
20
Children's Respiratory Infections in Tianjin Area, China: Associations with Home Environments and Lifestyles. 61
32517360 2020
21
A cross-reactive mouse monoclonal antibody against rhinovirus mediates phagocytosis in vitro. 61
32546721 2020
22
Effect of Panax ginseng on preventing acute respiratory tract infection: A protocol for systematic review and meta-analysis. 61
32541519 2020
23
Ethnobotanical study and phytochemical profiling of Heptapleurum hypoleucum leaf extract and evaluation of its antimicrobial activities against diarrhea-causing bacteria. 61
32537731 2020
24
Nontypeable Haemophilus influenzae Type IV pilus mediates augmented adherence to rhinovirus-infected human airway epithelial cells. 61
32540869 2020
25
Knowledge, attitudes, and practices of Egypt's future physicians towards antimicrobial resistance (KAP-AMR study): a multicenter cross-sectional study. 61
32270452 2020
26
An Aberration Detection-Based Approach for Sentinel Syndromic Surveillance of COVID-19 and Other Novel Influenza-Like Illnesses. 61
32577704 2020
27
COVID-19 pandemic: Impact caused by school closure and national lockdown on pediatric visits and admissions for viral and non-viral infections, a time series analysis. 61
32492117 2020
28
COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles' heel conserved region to minimize probability of escape mutations and drug resistance. 61
32568687 2020
29
A cluster of tertiary transmissions of 2019 novel coronavirus (SARS-CoV-2) in the community from infectors with common cold symptoms. 61
32506866 2020
30
Treatment of SARS-CoV-2 with high dose oral zinc salts: A report on four patients. 61
32522597 2020
31
Empirical Treatment and Prevention of COVID-19. 61
32476308 2020
32
Neurological manifestations of COVID-19, SARS and MERS. 61
32562214 2020
33
An Urgent Need for "Common Cold Units" to Study COVID-19. 61
32274988 2020
34
Predictive Value of Sudden Olfactory Loss in the Diagnosis of COVID-19. 61
32526759 2020
35
Respiratory Virus Infections: Understanding COVID-19. 61
32497522 2020
36
Fighting the Common Cold: ORMDL3 in the Crosshairs? 61
32109135 2020
37
Common Cold and Acute Rhinosinusitis: Up-to-Date Management in 2020. 61
32495003 2020
38
Facial Reconstruction Based on Combined Three-Dimensional Printing and Microsurgical Free Transfer. 61
32433137 2020
39
Protease Inhibitors: Candidate Drugs to Inhibit Severe Acute Respiratory Syndrome Coronavirus 2 Replication. 61
32448818 2020
40
Community antibiotic prescribing for children in France from 2015 to 2017: a cross-sectional national study. 61
32449915 2020
41
Rapid discrimination of Notopterygium incisum and Notopterygium franchetii based on characteristic compound profiles detected by UHPLC-QTOF-MS/MS coupled with multivariate analysis. 61
31908072 2020
42
Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells. 61
32094077 2020
43
Effects of cinnamon on controlling metabolic parameters of polycystic ovary syndrome: A systematic review and meta-analysis. 61
32151755 2020
44
Effects of different pediatric drugs and toothbrushing on color change of restorative materials used in pediatric dentistry. 61
32367866 2020
45
[Disease spectrum among guests and staff of an international luxury beach resort in the tropics]. 61
32383074 2020
46
ColdZyme® Mouth Spray reduces duration of upper respiratory tract infection symptoms in endurance athletes under free living conditions. 61
32419645 2020
47
Could nasal nitric oxide help to mitigate the severity of COVID-19? 61
32387333 2020
48
The outlook for diagnostic purposes of the 2019-novel coronavirus disease. 61
32452050 2020
49
Phase 1 LymfactinⓇ Study: Short-term Safety of Combined Adenoviral VEGF-C and Lymph Node Transfer Treatment for Upper Extremity Lymphedema. 61
32513642 2020
50
Counting the cost of COVID-19. 61
32412538 2020
Sources

Variations for Common Cold

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Sources

Expression for Common Cold

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Search GEO for disease gene expression data for Common Cold.
Sources

Pathways for Common Cold

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Pathways related to Common Cold according to GeneCards Suite gene sharing:

(show all 33)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 65
Show member pathways
 13.94 RNASE3 IL5 IL4 IL33 IL1R1 IL13
2
PEDF Induced Signaling 63
Show member pathways
 13.59 TSLP IL5 IL4 IL33 IL1R1 IL13
3
TGF-Beta Pathway 63
Show member pathways
 13.48 IL5 IL4 IL1R1 IL13 IFNA2 ICAM1
4
Akt Signaling 63
Show member pathways
 13.35 IL5 IL4 IL1R1 IL13 CXCL8 CCR6
5
PAK Pathway 63
Show member pathways
 13.24 IL5 IL4 IL1R1 IL13 CXCL8 CCR6
6
Cytokine Signaling in Immune system 65
Show member pathways
 13.24 IL5 IL4 IL33 IL1R1 IL13 IFNA2
7
Pathways in cancer 36
12.78 IL5 IL4 IL13 IFNA2 CXCL8
8
Measles 36
Show member pathways
 12.76 IL33 IFNA2 ICAM1 CXCL8 CCL5
9
Allograft rejection 1 36
Show member pathways
 12.72 RNASE3 IL5 IL4 IL13 IFNA2 ICOSLG
10
JAK-STAT signaling pathway 36
Show member pathways
 12.41 TSLP IL5 IL4 IL13 IFNA2
11
Immune response CCR3 signaling in eosinophils 22
Show member pathways
 12.29 ICAM1 CXCL8 CCL5 CCL11
12
IL-17 Family Signaling Pathways 64
Show member pathways
 12.29 IL5 IL4 IL13 CXCL8 CCL11
13
Folate Metabolism 1
Show member pathways
 12.28 LDLR IL4 ICAM1 CCL5 ALB
14
Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions 64
Show member pathways
 12.27 CXCL8 CCR6 CCL5 CCL11
15
Immune response IFN alpha/beta signaling pathway 22
Show member pathways
 12.22 IL5 IL4 IL13 IFNA2 CXCL8
16
Bacterial infections in CF airways 22
Show member pathways
 12.15 IL4 IL1R1 CXCL8 CCL11
17
Spinal Cord Injury 1
11.95 SELP IL4 IL1R1 ICAM1 CXCL8
18
Interleukin-4 and 13 signaling 65
11.91 IL4 IL13