Common Cold

Categories: Infectious diseases, Oral diseases, Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Common Cold

MalaCards integrated aliases for Common Cold:

Name: Common Cold 12 77 56 44 3 45 15 17 74
Acute Viral Rhinopharyngitis 12
Nasopharyngitis - Acute 12
Nasopharyngitis, Acute 12
Acute Nasopharyngitis 12
Rhino-Sinusitis 12
Acute Rhinitis 12
Rhinosinusitis 15
Acute Coryza 12
Common Colds 64


External Ids:

Disease Ontology 12 DOID:10459
ICD9CM 36 460
MeSH 45 D003139
SNOMED-CT 69 54150009 82272006
ICD10 34 J00
UMLS 74 C0009443

Summaries for Common Cold

MedlinePlus : 44 Sneezing, sore throat, a stuffy nose, coughing - everyone knows the symptoms of the common cold. It is probably the most common illness. In the course of a year, people in the United States suffer 1 billion colds. You can get a cold by touching your eyes or nose after you touch surfaces with cold germs on them. You can also inhale the germs. Symptoms usually begin 2 or 3 days after infection and last 2 to 14 days. Washing your hands and staying away from people with colds will help you avoid colds. There is no cure for the common cold. But there are treatments that can make you feel better while you wait for the cold to go away on its own: Getting plenty of rest Drinking fluids Gargling with warm salt water Using cough drops or throat sprays Taking over-the-counter pain or cold medicines However, do not give aspirin to children. And do not give cough medicine to children under four.

MalaCards based summary : Common Cold, also known as acute viral rhinopharyngitis, is related to pulmonary disease, chronic obstructive and viral infectious disease, and has symptoms including fever, pruritus and tinnitus. An important gene associated with Common Cold is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Montelukast and Capsaicin have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and testes, and related phenotypes are hematopoietic system and digestive/alimentary

Disease Ontology : 12 An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus.

CDC : 3 Sore throat and runny nose are usually the first signs of a cold, followed by coughing and sneezing. Most people recover in about 7-10 days. You can help reduce your risk of getting a cold: wash your hands often, avoid close contact with sick people, and don’t touch your face with unwashed hands.

PubMed Health : 64 About common colds: Common colds, or simply “colds,” are usually quite harmless and go away again on their own. Symptoms of a cold such as a cough, sore throat and a runny nose can be really annoying. A severe cold can make you feel weak and ill, too.Colds usually go away on their own after about a week, but some symptoms may last longer. Although a sore throat or a stuffy nose may be gone after just a few days, it can sometimes take up to three weeks for a cough to disappear completely.Treatment with medication usually isn’t necessary. Some medications may, at best, help relieve the symptoms a bit. Because colds are typically caused by viruses, it also doesn't make sense to use antibiotics to treat an ordinary cold. Antibiotics only work against bacteria.

Wikipedia : 77 The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory... more...

Related Diseases for Common Cold

Diseases related to Common Cold via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 270)
# Related Disease Score Top Affiliating Genes
1 pulmonary disease, chronic obstructive 32.2 CCL11 CCL5 CXCL8 IL13 RNASE3
2 viral infectious disease 31.3 CCL5 CXCL8 IFNA2
3 sinusitis 30.5 CXCL8 IL5 RNASE3
4 ige responsiveness, atopic 30.4 IL13 IL5 RNASE3
5 cytokine deficiency 30.3 IL13 IL5
6 cellulitis 30.3 IL1R1 IL5 RNASE3
7 otitis media 30.1 ALB CCL11 CXCL8 RNASE3
8 pyoderma 30.0 CXCL8 IFNA2 IL1R1
9 maxillary sinusitis 29.9 CCL5 RNASE3 SELP
10 bronchitis 29.9 ALB CCL11 CXCL8 IL5 RNASE3
11 rhinitis 29.5 CCL11 CCL5 CXCL8 ICAM1 IL13 IL5
12 allergic rhinitis 29.5 CCL11 CXCL8 ICAM1 IL13 IL5 RNASE3
13 dermatitis 29.4 CCL11 IL13 IL5 TSLP
14 food allergy 29.4 ALB IL13 IL5 RNASE3
15 allergic hypersensitivity disease 29.4 CCL11 CCL5 IL13 IL5 RNASE3 TSLP
16 hypereosinophilic syndrome 29.3 CCL11 IL13 IL5 RNASE3
17 pneumonia 29.3 CCL11 CCL5 CXCL8 IL13 IL5
18 allergic asthma 29.2 CCL11 CCL5 IL13 IL5 RNASE3 TSLP
19 esophagitis, eosinophilic, 1 29.2 CCL11 IL13 IL5 TSLP
20 myocardial infarction 29.0 ALB CCL5 ICAM1 LDLR POSTN SELP
21 bronchiolitis 29.0 CCL11 CCL5 CXCL8 IL13 IL5 RNASE3
22 esophagitis 28.9 CCL11 CXCL8 IL13 IL5 TSLP
23 dermatitis, atopic 28.5 CCL11 CCL5 CXCL8 ICAM1 IL13 IL5
24 asthma 28.4 CCL11 CCL5 CXCL8 ICAM1 IL13 IL1R1
25 malaria 27.9 ALB CCL11 CCL5 CXCL8 ICAM1 IL13
26 nasopharyngitis 11.5
27 influenza 11.3
28 otosalpingitis 11.2
29 young syndrome 11.1
30 ciliary dyskinesia, primary, 22 11.1
31 tonsillitis 10.9
32 pertussis 10.9
33 mda5 deficiency 10.9
34 papillary conjunctivitis 10.4 CCL11 CXCL8
35 chloramine t respiratory allergy 10.4 ALB RNASE3
36 heterophyiasis 10.4 ALB ICAM1
37 bone inflammation disease 10.4
38 pemphigoid gestationis 10.3 CCL11 IL5
39 st. louis encephalitis 10.3 IFNA2 RNASE3
40 vulvovaginitis 10.3 CCL11 CCL5 CXCL8
41 toxicodendron dermatitis 10.3 CXCL8 ICAM1
42 pyuria 10.3 ALB CXCL8
43 scabies 10.3 CCL11 CXCL8
44 herpes simplex virus keratitis 10.3 CXCL8 ICAM1
45 blepharoconjunctivitis 10.3 CCL11 RNASE3
46 bagassosis 10.3 CXCL8 IL5
47 spastic paraplegia, intellectual disability, nystagmus, and obesity 10.3
48 extrinsic allergic alveolitis 10.3 ALB CCL5 CXCL8
49 loeffler endocarditis 10.3 IL5 RNASE3
50 folliculitis 10.3 CCL11 CCL5 IL5

Graphical network of the top 20 diseases related to Common Cold:

Diseases related to Common Cold

Symptoms & Phenotypes for Common Cold

UMLS symptoms related to Common Cold:

fever, pruritus, tinnitus, snoring, rhinorrhea, sore throat, coughing, vertigo/dizziness, equilibration disorder, catarrh

MGI Mouse Phenotypes related to Common Cold:

# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.9 CCL11 CCL5 ICAM1 IL13 IL1R1 IL33
2 digestive/alimentary MP:0005381 9.8 ALB ICAM1 IL13 IL33 IL5 LDLR
3 immune system MP:0005387 9.7 CCL11 CCL5 ICAM1 IL13 IL1R1 IL33
4 respiratory system MP:0005388 9.17 CCL11 IL13 IL1R1 IL33 IL5 SELP

Drugs & Therapeutics for Common Cold

PubMedHealth treatment related to Common Cold: 64

Because there are so many different cold viruses, there is currently no medicine that can fight all cold viruses and shorten the length of colds. But various medications can relieve some of the symptoms a little. These include painkillers like ibuprofen and acetaminophen (paracetamol), as well as decongestant (anti-swelling) nasal sprays for temporary use.Antibiotics are usually not effective against colds and, because of their possible side effects, should only be used if there are complications. Products that contain zinc, vitamin C, or echinacea extracts are also commonly recommended for the treatment of colds. It's not currently possible to reliably evaluate the advantages and disadvantages of these herbal products because there has been little research in this area, and the studies that have been done have produced contradictory results. Herbal products like extracts taken from Pelargonium (umckaloabo), primrose, thyme, eucalyptus and ivy may possibly be able to relieve a cough somewhat.

Drugs for Common Cold (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 269)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Montelukast Approved Phase 4,Phase 3,Not Applicable 158966-92-8 5281040
Capsaicin Approved Phase 4,Phase 2 404-86-4 1548943
Ethanol Approved Phase 4,Not Applicable 64-17-5 702
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
Caffeine Approved Phase 4,Phase 3 58-08-2 2519
Acetaminophen Approved Phase 4,Phase 3,Phase 2,Phase 1 103-90-2 1983
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
Histamine Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 51-45-6 774
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 93-14-1 3516
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1491-59-4 4636
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-42-7 6041
Ipratropium Approved, Experimental Phase 4 22254-24-6, 60205-81-4 657309 43232
Dextromethorphan Approved Phase 4,Phase 3,Phase 1 125-71-3 5362449 5360696
Thyme Approved Phase 4,Not Applicable
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3 55-56-1 2713 9552079
Echinacea Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable
Oseltamivir Approved Phase 4 204255-11-8, 196618-13-0 65028
Azelastine Approved Phase 4,Phase 3 58581-89-8 2267
21 Orange Approved Phase 4,Not Applicable
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
Vitamin C Approved, Nutraceutical Phase 4,Phase 3,Not Applicable 50-81-7 54670067 5785
Glycine Approved, Nutraceutical, Vet_approved Phase 4 56-40-6 750
25 Andrographolide Investigational Phase 4,Not Applicable 5508-58-7
Maleic acid Experimental, Investigational Phase 4,Phase 3 110-17-8, 110-16-7 444972
BCG vaccine Investigational Phase 4
28 Hormones Phase 4,Phase 3,Phase 2,Not Applicable
29 Anti-Asthmatic Agents Phase 4,Phase 3,Phase 2,Not Applicable
30 Hormone Antagonists Phase 4,Phase 3,Not Applicable
31 Leukotriene Antagonists Phase 4,Not Applicable
32 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Not Applicable
33 Respiratory System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
34 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Dermatologic Agents Phase 4,Phase 3,Phase 2,Phase 1
36 Antipruritics Phase 4,Phase 3,Phase 2,Phase 1
37 Sodium Benzoate Phase 4
38 Antifungal Agents Phase 4
39 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Antirheumatic Agents Phase 4,Phase 3
42 Platelet Aggregation Inhibitors Phase 4,Phase 3
43 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
44 Anti-Inflammatory Agents Phase 4,Phase 3,Not Applicable
45 Andrographis Phase 4,Not Applicable
46 Antiparasitic Agents Phase 4
47 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
48 Antiprotozoal Agents Phase 4
49 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
50 Antipyretics Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 236)
# Name Status NCT ID Phase Drugs
1 A Study of Arbidol (Umifenovir) for Treatment and Prophylaxis of Influenza and Common Cold Unknown status NCT01651663 Phase 4 Arbidol (Umifenovir);Arbidol (Umifenovir)
2 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
3 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
4 Bromelin, a Compound Prepared With Ananas Comocus Extract and Honey, for Acute Cough Unknown status NCT01356693 Phase 4 Bromelin;Placebo
5 Montelukast for Persistent Cough in Young People and Adults Unknown status NCT01279668 Phase 4 Montelukast;Placebo
6 A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis Unknown status NCT03132610 Phase 4 andrographolide sulfonate;andrographolide sulfonate simulation
7 Evaluate the Efficacy and Safety of Andrographolide Sulfonate in Patients With Acute Tonsillitis Unknown status NCT03134443 Phase 4 Andrographolide sulfonate;Andrographolide sulfonate simulation
8 Effects of a Common Cold Treatment on Cognitive Function Completed NCT01466348 Phase 4 Paracetamol and Caffeine;Paracetamol
9 Symptomatic Treatment of Common Cold Symptoms Completed NCT01033526 Phase 4 Aspirin (Acetylsalicylic acid, BAYE4465);Placebo
10 Iota-Carrageenan Nasal Spray in Common Cold Completed NCT01944631 Phase 4
11 Safety Trial of Atrovent® in Pediatric Patients With Rhinorrhea Associated With a Common Cold or Allergy Completed NCT02238210 Phase 4 Atrovent®
12 The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza. Completed NCT02246166 Phase 4 Test tablet
13 Placebo and Active Controlled Study to Compare the Efficacy of Aspirin and Paracetamol in Treatment of Sore Throat Associated With a Common Cold Completed NCT01465009 Phase 4 Acetylsalicylic acid (Aspirin, BAYE4465);Paracetamol;Placebo
14 Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold Completed NCT00378144 Phase 4 Pseudoephedrine/Paracetamol
15 PEACe: Ivy, Thyme and Cisti Extract (Phytus) Efficacy in Acute Cough Completed NCT02981147 Phase 4 Phytus (Cisti, Thyme and Ivy Leaves)
16 A Comparison of Solid and Soluble Forms of Cold and Influenza Remedies Completed NCT01332578 Phase 4 Paracetamol;Phenylephrine;Ascorbic Acid
17 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction Completed NCT01847131 Phase 4 oxymetazoline;Placebo nasal spray
18 Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections Completed NCT01728090 Phase 4
19 Comparison of Efficacy and Tolerability of Two Cough Syrups in Cough Due to Cold in Children. Completed NCT01968434 Phase 4 carbocisteine cough syrup
20 Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults Completed NCT03154515 Phase 4 Ingavirin;Placebo
21 Evaluate the Potential of Montelukast to Prevent Nasal Symptomatology During Colds Completed NCT00189475 Phase 4 Montelukast
22 Efficacy and Safety of Imuneks 10 mg Capsules in the Prophylaxis of Cold Completed NCT02807220 Phase 4 Imuneks 10mg
23 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
24 Echinacea Safety Study Completed NCT01021995 Phase 4 echinacea;placebo
25 Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis Completed NCT00000411 Phase 4
26 Prevention of RSV Infections in Bone Marrow Transplant Recipients Completed NCT00001903 Phase 4 RSV Polyclonal Immunoglobulin
27 A Study of Oseltamivir (Tamiflu) for the Seasonal Prophylaxis of Influenza in Immunocompromised Participants Completed NCT00412737 Phase 4 Oseltamivir;Placebo
28 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
29 Effect of OM-85 BV on Wheezing Related Morbidity in Children With Recurrent Wheezing Completed NCT00733226 Phase 4 OM-85 BV (Broncho-Vaxom);OM-85 BV (placebo)
30 Dextromethorphan Pediatric Acute Cough Study Recruiting NCT02651116 Phase 4 Dextromethorphan Hydrobromide;Placebo
31 Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea Recruiting NCT02630121 Phase 4 Oxymetazoline Hydrochloride;Placebo
32 Immune Response to High-Dose vs. Standard Dose Influenza Vaccine Active, not recruiting NCT02297542 Phase 4
33 Non-specific Effects of Rabies Vaccine Enrolling by invitation NCT03656198 Phase 4 Sterile Water Injection
34 Acute Cough Study In Children Terminated NCT01257542 Phase 4 Dextromethorphan;Placebo
35 Study Of RV-39 In Patients Who Also Have Asthma Terminated NCT00503009 Phase 4 fluticasone propionate/salmeterol;fluticasone propionate;placebo
36 Echinaforce Junior Bioavailability Trial Withdrawn NCT03070314 Phase 4 Echinaforce junior
37 Study Comparing Coristina® D to Resfenol® in the Symptomatic Treatment of Common Cold Unknown status NCT02735070 Phase 3 Resfenol;Coristina d
38 Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome Unknown status NCT00940836 Phase 3 Resfenol;Placebo;Co interventional acetaminophen
39 Effectiveness and Safety of the of Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup in Improvement of Symptoms Resulting From Acute Respiratory Infections. Unknown status NCT00857987 Phase 3 EMS Expectorant
40 Mepolizumab Treatment for Rhinovirus-induced Asthma Exacerbations Unknown status NCT01520051 Phase 3 Mepolizumab;Placebo
41 Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants Unknown status NCT01249911 Phase 3
42 Effects of Two Doses of a Common Cold Treatment on Alertness Completed NCT01686646 Phase 3 paracetamol + caffeine;paracetamol
43 Decongestant Effect, Timing of Effect and Impact on Sleep and General Well-Being of Xylometazoline in Subjects With a Common Cold Completed NCT00452270 Phase 3 Xylometazoline
44 Evaluation of Efficacy and Safety of Oral Solution Resfenol in Reducing Symptoms of Common Cold And Flu Completed NCT01158326 Phase 3 Resfenol
45 A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold Completed NCT01744106 Phase 3 pseudoephedrine hydrochloride 30 mg tablets;Placebo tablets
46 Echinacea Versus Placebo Effect in Common Cold (Physician Echinacea Placebo) Completed NCT00065715 Phase 3
47 Pomegranate Products for Prevention of Common Cold Completed NCT00617318 Phase 3
48 Efficacy and Safety of Paracetamol, Chlorpheniramine and Phenylephrine in the Treatment of Common Cold and Flu Syndrome Completed NCT01389518 Phase 3 Active;Placebo
49 Active and Placebo Controlled Study to Test the Efficacy and Safety of an Aspirin-Lidocaine Lozenge in the Symptomatic Treatment of Sore Throat Associated With a Common Cold Completed NCT01361399 Phase 3 Acetylsalicylic acid (Aspirin, BAYE4465) & Lidocain;Acetylsalicylic Acid (Aspirin, BAYE4465);Lidocain;Placebo
50 Safety and Intake Effect of EPs® 7630 (an Extract of the Roots of Pelargonium Sidoides) Completed NCT02174653 Phase 3 EPs® 7630;Placebo

Search NIH Clinical Center for Common Cold

Inferred drug relations via UMLS 74 / NDF-RT 52 :

Cochrane evidence based reviews: common cold

Genetic Tests for Common Cold

Anatomical Context for Common Cold

MalaCards organs/tissues related to Common Cold:

Eye, Bone, Testes, Breast, Lung, Bone Marrow, Tonsil

Publications for Common Cold

Articles related to Common Cold:

(show top 50) (show all 1163)
# Title Authors Year
Short-course administration of a traditional herbal mixture ameliorates asthma symptoms of the common cold in children. ( 30984577 )
The use of a poster to reduce expectations to receive antibiotics for a common cold. ( 31102079 )
Non-interventional observational study broadens positive benefit-risk assessment of an immunomodulating herbal remedy in the common cold. ( 31074674 )
Assessment of patient counselling on the common cold treatment at Slovak community pharmacies using mystery shopping. ( 31061627 )
Not just the common cold: Rhinovirus infection in lung allograft recipients. ( 31004394 )
Safety and Efficacy of 0.5% Carbomer 980 Gel for Treatment of Symptoms of Common Cold: Results of 2 Randomized Trials. ( 31004286 )
Tackling the outcome bias related to the effectiveness of antibiotics against the common cold: results of a randomized controlled trial applying the Solomon four-group design. ( 30926995 )
Binafuxi granules in the treatment of common cold with heat syndrome based on traditional Uighur medicine: study protocol for a multicenter randomized controlled trial. ( 30922355 )
Antibiotic prescription for under-fives with common cold or upper respiratory tract infection in Savannakhet Province, Lao PDR. ( 30858755 )
The Common Cold. ( 30829428 )
A pilot, open labelled, randomised controlled trial of hypertonic saline nasal irrigation and gargling for the common cold. ( 30705369 )
A case series on common cold to severe bronchiolitis and pneumonia in children following human metapneumovirus infection in Sri Lanka. ( 29444701 )
Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens. ( 29111214 )
Efficacy and Tolerability of High-dose Pelargonium Extract in Patients With the Common Cold. ( 29055287 )
Effects of common cold and concomitant administration of nasal decongestant on the pharmacokinetics and pharmacodynamics of nasal glucagon in otherwise healthy participants: A randomized clinical trial. ( 29053231 )
Healthier without healthcare? The paradox of the common cold. ( 30587182 )
Human Rhinovirus Inhibits Macrophage Phagocytosis of Bacteria in COPD: More than a Common Cold. ( 30571921 )
"With fever it's the real flu I would say": laypersons' perception of common cold and influenza and their differences - a qualitative study in Austria, Belgium and Croatia. ( 30541479 )
Soshiho-tang for treating common cold in children younger than 12 years: A systematic review and meta-analysis of randomized controlled trials. ( 30407301 )
What are the effects of vitamin C on the duration and severity of the common cold? ( 30339136 )
What treatments are effective for common cold in adults and children? ( 30305295 )
Effects of orally administered lactoferrin and lactoperoxidase on symptoms of the common cold. ( 30202407 )
Does vitamin C prevent the common cold? ( 30113569 )
Eunkyosan for treatment of the common cold: A protocol for the systematic review of controlled trials: Erratum. ( 30113505 )
Effects of paraprobiotic Lactobacillus paracasei MCC1849 supplementation on symptoms of the common cold and mood states in healthy adults. ( 30099891 )
Antibiotic use in the management of children with the common cold at a provincial hospital in Papua New Guinea: a point-prevalence study. ( 30079842 )
Phenylephrine, a common cold remedy active ingredient, suppresses uterine contractions through cAMP signalling. ( 30076382 )
Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials. ( 30069463 )
Effect of Tea Catechins on Influenza Infection and the Common Cold with a Focus on Epidemiological/Clinical Studies. ( 30037024 )
A potential cure for the common cold. ( 29789723 )
Potential common factors associated with predisposition to common cold in middle-aged and elderly Japanese: A community-based cross-sectional study. ( 29768343 )
Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. ( 29760414 )
Eunkyosan for treatment of the common cold: A protocol for the systematic review of controlled trials. ( 29718842 )
Randomised controlled trial of rhinothermy for treatment of the common cold: a feasibility study. ( 29593018 )
Acupuncture for common cold: A systematic review and meta-analyze protocol. ( 29517665 )
Smoking, leisure-time exercise and frequency of self-reported common cold among the general population in northeastern China: a cross-sectional study. ( 29486739 )
Prenatal exposure to ambient temperature variation increases the risk of common cold in children. ( 29476971 )
Diagnostic delay for imported malaria: A case of Plasmodium falciparum malaria misdiagnosed as common cold. ( 29340263 )
Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population. ( 29301349 )
Efficacy and safety of Reduqing granules in the treatment of common cold with wind-heat syndrome: a randomized, double-blind, double-dummy, positive-controlled trial. ( 29960290 )
Soothing Properties of Glycerol in Cough Syrups for Acute Cough Due to Common Cold. ( 28970416 )
Heated, humidified air for the common cold. ( 28849871 )
Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold: CHEST Expert Panel Report. ( 28837801 )
Is Corticosteroid of No Use for Pediatric Patients with Common Cold Undergoing Anesthesia? A Randomized, Double-Blind, Clinical Trial. ( 28824868 )
Trend Of Irrational Medication Among The Students Of Department Of Pharmacy Abbottabad University Of Science And Technology In Common Cold And Flu. ( 28712182 )
Rhinovirus - not just the common cold. ( 28646961 )
Offspring of parents who were separated and not speaking to one another have reduced resistance to the common cold as adults. ( 28584098 )
MEWDS, Common Cold of the Retina. ( 28540002 )
Vaccines for the common cold. ( 28516442 )
Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage. ( 28515951 )

Variations for Common Cold

Expression for Common Cold

Search GEO for disease gene expression data for Common Cold.

Pathways for Common Cold

Pathways related to Common Cold according to GeneCards Suite gene sharing:

(show all 28)
# Super pathways Score Top Affiliating Genes
Show member pathways
Show member pathways
13.55 CCL11 CCL5 CXCL8 IFNA2 IL13 IL1R1
Show member pathways
Show member pathways
Show member pathways
Show member pathways
12.3 IFNA2 IL13 IL5 TSLP
Show member pathways
12.23 CCL11 CCL5 CXCL8 ICAM1
Show member pathways
Show member pathways
12.2 CCL11 CXCL8 IL13 IL5
Show member pathways
12.13 CCL11 CCL5 CXCL8 ICAM1 IL1R1
11 11.89 CXCL8 ICAM1 IL1R1 SELP
Show member pathways
11.88 CCL11 CCL5 CXCL8
13 11.85 CCL11 CXCL8 ICAM1 IL13
Show member pathways
11.81 CCL11 CCL5 CXCL8 ICAM1 IL13 IL1R1
15 11.8 CXCL8 ICAM1 IL1R1
16 11.75 CCL5 CXCL8 ICAM1
17 11.69 CXCL8 ICAM1 IL13 IL5
18 11.61 CCL11 CCL5 IL13
19 11.52 CCL11 IL5 SELP
20 11.46 IL13 IL1R1 IL33 IL5 TSLP
21 11.4 CXCL8 ICAM1 SELP
22 11.37 CCL11 CXCL8 TSLP
23 11.37 CCL11 IL13 IL33 IL5
24 11.17 IL13 IL33 IL5 TSLP
25 11.15 CCL11 CCL5 CXCL8 IL13 IL5
26 11.09 CCL11 CCL5 CXCL8 IL13 IL5
27 10.92 CCL11 CCL5 CXCL8 IL13 IL5
28 10.71 CCL5 CXCL8 ICAM1 IL13 IL1R1

GO Terms for Common Cold

Cellular components related to Common Cold according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.77 ALB CCL11 CCL5 CXCL8 IFNA2 IL13
2 external side of plasma membrane GO:0009897 9.63 ICAM1 ICOSLG IL13 IL1R1 LDLR SELP
3 extracellular space GO:0005615 9.5 ALB CCL11 CCL5 CXCL8 ICAM1 IFNA2

Biological processes related to Common Cold according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.91 CCL11 CCL5 CXCL8 IL13 IL1R1 IL5
2 regulation of signaling receptor activity GO:0010469 9.76 CCL11 CCL5 CXCL8 IFNA2 IL13 IL33
3 cellular response to interferon-gamma GO:0071346 9.75 CCL11 CCL5 ICAM1
4 neutrophil chemotaxis GO:0030593 9.72 CCL11 CCL5 CXCL8
5 positive regulation of inflammatory response GO:0050729 9.7 IL33 LDLR TSLP
6 chemokine-mediated signaling pathway GO:0070098 9.69 CCL11 CCL5 CXCL8
7 cellular response to interleukin-1 GO:0071347 9.67 CCL11 CCL5 CXCL8 ICAM1
8 cellular response to tumor necrosis factor GO:0071356 9.65 CCL11 CCL5 CXCL8 ICAM1 POSTN
9 cellular response to fibroblast growth factor stimulus GO:0044344 9.63 CCL5 CXCL8 POSTN
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.62 CCL5 IFNA2 IL13 TSLP
11 positive regulation of smooth muscle cell migration GO:0014911 9.59 CCL5 POSTN
12 positive regulation of macrophage activation GO:0043032 9.58 IL13 IL33
13 leukocyte cell-cell adhesion GO:0007159 9.58 CCL5 ICAM1 SELP
14 negative regulation of G protein-coupled receptor signaling pathway GO:0045744 9.57 CCL5 CXCL8
15 positive regulation of immunoglobulin secretion GO:0051024 9.56 IL33 IL5
16 inflammatory response GO:0006954 9.56 CCL11 CCL5 CXCL8 IFNA2 IL13 IL1R1
17 neutrophil activation GO:0042119 9.54 CCL5 CXCL8
18 positive regulation of interleukin-13 production GO:0032736 9.49 IL33 TSLP
19 positive regulation of interleukin-5 production GO:0032754 9.48 IL33 TSLP
20 cytokine-mediated signaling pathway GO:0019221 9.23 CCL11 CCL5 CXCL8 ICAM1 IFNA2 IL13

Molecular functions related to Common Cold according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemokine activity GO:0008009 9.33 CCL11 CCL5 CXCL8
2 low-density lipoprotein particle receptor activity GO:0005041 9.26 LDLR VLDLR
3 cytokine activity GO:0005125 9.23 CCL11 CCL5 CXCL8 IFNA2 IL13 IL33
4 very-low-density lipoprotein particle receptor activity GO:0030229 8.96 LDLR VLDLR

Sources for Common Cold

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
33 HPO
34 ICD10
35 ICD10 via Orphanet
39 LifeMap
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
56 Novoseek
59 OMIM via Orphanet
63 PubMed
71 SNOMED-CT via Orphanet
73 Tocris
75 UMLS via Orphanet
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