MCID: CMP031
MIFTS: 12

Complement Component Deficiency

Categories: Rare diseases

Aliases & Classifications for Complement Component Deficiency

MalaCards integrated aliases for Complement Component Deficiency:

Name: Complement Component Deficiency 53 73

Classifications:



External Ids:

UMLS 73 C1285186

Summaries for Complement Component Deficiency

MalaCards based summary : Complement Component Deficiency is related to glomerulonephritis and complement component 3 deficiency, autosomal recessive. An important gene associated with Complement Component Deficiency is C1QA (Complement C1q A Chain). The drugs Oxaliplatin and s 1 (combination) have been mentioned in the context of this disorder.

Related Diseases for Complement Component Deficiency

Diseases related to Complement Component Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 glomerulonephritis 9.8
2 complement component 3 deficiency, autosomal recessive 9.7
3 rheumatic disease 9.7
4 enthesopathy 9.7
5 membranoproliferative glomerulonephritis 9.7
6 neisseria meningitidis infection 9.7

Graphical network of the top 20 diseases related to Complement Component Deficiency:



Diseases related to Complement Component Deficiency

Symptoms & Phenotypes for Complement Component Deficiency

Drugs & Therapeutics for Complement Component Deficiency

Drugs for Complement Component Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Oxaliplatin Approved, Investigational 61825-94-3 5310940 9887054 43805 6857599
2
s 1 (combination)
3 Complement C3
4 Complement System Proteins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Predictive Value of Complement C3 in Patients With Advanced Gastric Cancer Completed NCT02425930 S-1+Oxaliplatin

Search NIH Clinical Center for Complement Component Deficiency

Genetic Tests for Complement Component Deficiency

Anatomical Context for Complement Component Deficiency

Publications for Complement Component Deficiency

Articles related to Complement Component Deficiency:

# Title Authors Year
1
Early Complement Component Deficiency in a Single-Centre Cohort of Pediatric Onset Lupus. ( 26563161 )
2015
2
Complementing the patient: a complement component deficiency in a patient with recurrent infections and glomerulonephritis. ( 16285472 )
2005
3
Meningococcal disease in patients with late complement component deficiency: studies in the U.S.S.R. ( 8231787 )
1993
4
Complement component deficiencies and infection: C5, C8 and C3 deficiencies in three families. ( 1396929 )
1992
5
Terminal complement component deficiencies and rheumatic disease: development of a rheumatic syndrome and anticomplementary activity in a patient with complete C6 deficiency. ( 3931570 )
1985
6
Inherited complement component deficiencies in membranoproliferative glomerulonephritis. ( 6663990 )
1983

Variations for Complement Component Deficiency

Expression for Complement Component Deficiency

Search GEO for disease gene expression data for Complement Component Deficiency.

Pathways for Complement Component Deficiency

GO Terms for Complement Component Deficiency

Sources for Complement Component Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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