MCID: CMP031
MIFTS: 12

Complement Component Deficiency

Categories: Rare diseases

Aliases & Classifications for Complement Component Deficiency

MalaCards integrated aliases for Complement Component Deficiency:

Name: Complement Component Deficiency 53 72

Classifications:



External Ids:

UMLS 72 C1285186

Summaries for Complement Component Deficiency

MalaCards based summary : Complement Component Deficiency is related to neisseria meningitidis infection and complement component 5 deficiency. An important gene associated with Complement Component Deficiency is C1QA (Complement C1q A Chain). Affiliated tissues include neutrophil.

Related Diseases for Complement Component Deficiency

Graphical network of the top 20 diseases related to Complement Component Deficiency:



Diseases related to Complement Component Deficiency

Symptoms & Phenotypes for Complement Component Deficiency

Drugs & Therapeutics for Complement Component Deficiency

Search Clinical Trials , NIH Clinical Center for Complement Component Deficiency

Genetic Tests for Complement Component Deficiency

Anatomical Context for Complement Component Deficiency

MalaCards organs/tissues related to Complement Component Deficiency:

41
Neutrophil

Publications for Complement Component Deficiency

Articles related to Complement Component Deficiency:

(show all 35)
# Title Authors PMID Year
1
A Fatal Case of Invasive Infection Caused By W135 Neisseria meningitidis in a Vaccinated French Soldier. 38
27849512 2016
2
Early Complement Component Deficiency in a Single-Centre Cohort of Pediatric Onset Lupus. 38
26563161 2015
3
Relationships Between Clinico-Epidemiological Patterns of Invasive Meningococcal Infections and Complement Deficiencies in French South Pacific Islands (New Caledonia). 38
25352052 2015
4
Updated recommendations for use of meningococcal conjugate vaccines --- Advisory Committee on Immunization Practices (ACIP), 2010. 38
21270745 2011
5
High prevalence of primary immune deficiencies in children with autoimmune disorders. 38
21345299 2011
6
Renal disease associated with inherited disorders of the complement system. 38
18958500 2009
7
Increased serum complement component 3 and mannose-binding lectin levels in adult Chinese patients with chronic rhinosinusitis. 38
19593977 2009
8
[Complement protein hereditary deficits during purulent meningitis: study of 61 adult Tunisian patients]. 38
19388594 2006
9
Complementing the patient: a complement component deficiency in a patient with recurrent infections and glomerulonephritis. 38
16285472 2005
10
Long term effects of vaccination of patients deficient in a late complement component with a tetravalent meningococcal polysaccharide vaccine. 38
14505927 2003
11
Early manifestation and recognition of C2 complement deficiency in the form of pyogenic infection in infancy. 38
12755933 2003
12
Antibody-dependent killing of meningococci by human neutrophils in serum of late complement component-deficient patients. 38
12740533 2003
13
The role of Fcgamma receptor polymorphisms and C3 in the immune defence against Neisseria meningitidis in complement-deficient individuals. 38
10792385 2000
14
[The bactericidal action of human neutrophils on meningococci in vitro]. 38
10851990 1999
15
[Clinical features of meningococcal infection in subjects with deficient terminal components of complement]. 38
10626326 1999
16
Protection against meningococcal serogroup ACYW disease in complement-deficient individuals vaccinated with the tetravalent meningococcal capsular polysaccharide vaccine. 38
9844044 1998
17
The effect of mannan-binding lectin on opsonophagocytosis of Neisseria meningitidis. 38
9476120 1997
18
Heterozygous C8beta complement deficiency does not predispose to meningococcal disease. 38
9182898 1997
19
Vaccination of patients deficient in a late complement component with tetravalent meningococcal capsular polysaccharide vaccine. 38
7697919 1995
20
[Homozygote CB deficiency revealed by recurrent Neisseria meningitidis infections in an adolescent]. 38
7842072 1994
21
Hereditary deficiency of the seventh component of complement and recurrent meningococcal infection: investigations of an Irish family using a novel haemolytic screening assay for complement activity and C7 M/N allotyping. 38
7523157 1994
22
Meningococcal disease in patients with late complement component deficiency: studies in the U.S.S.R. 38
8231787 1993
23
Regulation of antibody responses: the role of complement and adhesion molecules. 38
8500279 1993
24
Complement deficiency states and meningococcal disease. 38
8288947 1993
25
Inherited deficiencies of the late-acting complement components other than C9 found among healthy blood donors. 38
2592116 1989
26
Complement levels in dogs with familial canine dermatomyositis. 38
3238922 1988
27
Systemic lupus erythematosus with complement deficiency and IgA anti-cardiolipin antibody. 38
3207615 1988
28
[Complement component deficiency and autoimmune diseases]. 38
3056794 1988
29
Immunoregulatory disorders associated with hereditary angioedema. II. Serologic and cellular abnormalities. 38
3486201 1986
30
[Complement component deficiency]. 38
4094102 1985
31
Bacterial meningitis in the patient at risk: intrinsic risk factors and host defense mechanisms. 38
6372470 1984
32
C2 deficient systemic lupus erythematosus: its association with anti-Ro (SSA) antibodies. 38
6980631 1982
33
Phagocytosis, chemoluminescence, and intracellular killing of fungi by phagocytes from subjects with deficiency of the second component of complement. 38
7042584 1982
34
Meningococcal meningitis in familial deficiency of the fifth component of complement. 38
6785713 1981
35
The genetics of the complement system. 38
258168 1979

Variations for Complement Component Deficiency

Expression for Complement Component Deficiency

Search GEO for disease gene expression data for Complement Component Deficiency.

Pathways for Complement Component Deficiency

GO Terms for Complement Component Deficiency

Sources for Complement Component Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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