MCID: CMP031
MIFTS: 11

Complement Component Deficiency

Categories: Rare diseases

Aliases & Classifications for Complement Component Deficiency

MalaCards integrated aliases for Complement Component Deficiency:

Name: Complement Component Deficiency 54 74

Classifications:



External Ids:

UMLS 74 C1285186

Summaries for Complement Component Deficiency

MalaCards based summary : Complement Component Deficiency is related to glomerulonephritis and rheumatic disease. An important gene associated with Complement Component Deficiency is C1QA (Complement C1q A Chain). The drugs Oxaliplatin and Complement C3 have been mentioned in the context of this disorder.

Related Diseases for Complement Component Deficiency

Diseases related to Complement Component Deficiency via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 glomerulonephritis 9.9
2 rheumatic disease 9.8
3 membranoproliferative glomerulonephritis 9.8
4 neisseria meningitidis infection 9.8

Symptoms & Phenotypes for Complement Component Deficiency

Drugs & Therapeutics for Complement Component Deficiency

Drugs for Complement Component Deficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Oxaliplatin Approved, Investigational 61825-94-3 6857599 5310940 9887054 43805
2 Complement C3
3 Immunologic Factors
4 Complement System Proteins
5
s 1 (combination)

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Predictive Value of Complement C3 in Patients With Advanced Gastric Cancer Completed NCT02425930 S-1+Oxaliplatin

Search NIH Clinical Center for Complement Component Deficiency

Genetic Tests for Complement Component Deficiency

Anatomical Context for Complement Component Deficiency

Publications for Complement Component Deficiency

Articles related to Complement Component Deficiency:

# Title Authors Year
1
Early Complement Component Deficiency in a Single-Centre Cohort of Pediatric Onset Lupus. ( 26563161 )
2015
2
Complementing the patient: a complement component deficiency in a patient with recurrent infections and glomerulonephritis. ( 16285472 )
2005
3
Meningococcal disease in patients with late complement component deficiency: studies in the U.S.S.R. ( 8231787 )
1993

Variations for Complement Component Deficiency

Expression for Complement Component Deficiency

Search GEO for disease gene expression data for Complement Component Deficiency.

Pathways for Complement Component Deficiency

GO Terms for Complement Component Deficiency

Sources for Complement Component Deficiency

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....