CAVC
MCID: CMP035
MIFTS: 30

Complete Atrioventricular Canal (CAVC)

Categories: Cardiovascular diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Complete Atrioventricular Canal

MalaCards integrated aliases for Complete Atrioventricular Canal:

Name: Complete Atrioventricular Canal 53 59
Common Atrioventricular Canal 53 59 73
Complete Atrioventricular Septal Defect 53 59
Cavc 53 59
Complete Atrioventricular Canal Defect 29

Characteristics:

Orphanet epidemiological data:

59
complete atrioventricular canal
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: Infancy,Neonatal;

Classifications:



External Ids:

Orphanet 59 ORPHA1329
UMLS via Orphanet 74 C0221215 C0344787
ICD10 via Orphanet 34 Q21.2
SNOMED-CT via HPO 69 253273004 396351009 59494005
UMLS 73 C0221215

Summaries for Complete Atrioventricular Canal

MalaCards based summary : Complete Atrioventricular Canal, also known as common atrioventricular canal, is related to complete atrioventricular canal-tetralogy of fallot syndrome and complete atrioventricular canal-ventricle hypoplasia syndrome. An important gene associated with Complete Atrioventricular Canal is LEFTY2 (Left-Right Determination Factor 2). Affiliated tissues include heart, lung and small intestine, and related phenotypes are abnormality of the cardiac septa and abnormal cardiac septum morphology

Related Diseases for Complete Atrioventricular Canal

Diseases related to Complete Atrioventricular Canal via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 complete atrioventricular canal-tetralogy of fallot syndrome 12.4
2 complete atrioventricular canal-ventricle hypoplasia syndrome 12.4
3 complete atrioventricular canal-left heart obstruction syndrome 12.4
4 partial atrioventricular canal 11.4
5 tetralogy of fallot 10.6
6 double outlet right ventricle 10.4
7 aortopulmonary window 10.3
8 down syndrome 10.2
9 cor triatriatum 10.2
10 pulmonary hypertension, primary, 1 10.2
11 pulmonary hypertension 10.2
12 pulmonary vein stenosis 10.2
13 ventricular septal defect 10.1
14 vascular disease 10.1
15 transposition of the great arteries 10.1
16 atrial heart septal defect 10.1
17 aortic arch interruption 10.0
18 infective endocarditis 10.0
19 aortic coarctation 10.0
20 chromosomal triplication 10.0
21 hypoxia 10.0
22 noonan syndrome 1 9.9
23 williams-beuren syndrome 9.9
24 heterotaxy, visceral, 1, x-linked 9.9
25 tricuspid atresia 9.9
26 atrioventricular septal defect 9.9
27 chromosome 3pter-p25 deletion syndrome 9.9
28 endocarditis 9.9
29 mitral valve insufficiency 9.9
30 situs inversus 9.9
31 dextrocardia 9.9
32 heterotaxy 9.9
33 hypertrophic cardiomyopathy 9.9
34 atrial septal defect coronary sinus 9.9
35 congenitally corrected transposition of the great arteries 9.9
36 double discordia 9.9
37 pseudo-turner syndrome 9.9
38 right atrial isomerism 9.9
39 conotruncal heart malformations 9.9
40 ebstein anomaly 9.9
41 ellis-van creveld syndrome 9.9
42 mitral atresia 9.9

Graphical network of the top 20 diseases related to Complete Atrioventricular Canal:



Diseases related to Complete Atrioventricular Canal

Symptoms & Phenotypes for Complete Atrioventricular Canal

Human phenotypes related to Complete Atrioventricular Canal:

59 32
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 abnormality of the cardiac septa 59 Very frequent (99-80%)
2 abnormal cardiac septum morphology 32 hallmark (90%) HP:0001671

Drugs & Therapeutics for Complete Atrioventricular Canal

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of Triostat in Infants During Heart Surgery Completed NCT00027417 Phase 3 Liothyronine sodium/triiodothyronine
2 Infant Weight Gain With Trisomy 21 and CAVC Terminated NCT00327951
3 Optimal Timing for Repair of Left to Right Shunt Lesions Terminated NCT00229827

Search NIH Clinical Center for Complete Atrioventricular Canal

Genetic Tests for Complete Atrioventricular Canal

Genetic tests related to Complete Atrioventricular Canal:

# Genetic test Affiliating Genes
1 Complete Atrioventricular Canal Defect 29

Anatomical Context for Complete Atrioventricular Canal

MalaCards organs/tissues related to Complete Atrioventricular Canal:

41
Heart, Lung, Small Intestine

Publications for Complete Atrioventricular Canal

Articles related to Complete Atrioventricular Canal:

(show top 50) (show all 215)
# Title Authors Year
1
Retrospective study of complete atrioventricular canal defects: Anesthetic and perioperative challenges. ( 29336386 )
2018
2
Complete atrioventricular canal repair with a decellularized porcine small intestinal submucosa patch. ( 30242970 )
2018
3
Bloodless Heart Surgery for an 11-kg Infant of the Jehovah's Witness Faith Undergoing Second Repair for Complete Atrioventricular Canal. ( 30250346 )
2018
4
Echocardiographic Assessment of Complete Atrioventricular Canal Defects: A Balancing Act. ( 30447289 )
2018
5
Cardiac Function After Tetralogy of Fallot/Complete Atrioventricular Canal Repair. ( 28329461 )
2017
6
Complete Atrioventricular Canal Defect: Towards a More Physiological Repair. ( 28705664 )
2017
7
Biventricular repair for common atrioventricular canal defect with parachute left atrioventricular valve. ( 25838456 )
2016
8
Early Complete Atrioventricular Canal Repair Yields Outcomes Equivalent to Late Repair. ( 25886812 )
2015
9
Palliation of Truncus Arteriosus Associated With Complete Atrioventricular Canal-Results of Single Ventricle Palliation. ( 26467884 )
2015
10
Atypical Williams syndrome in an infant with complete atrioventricular canal defect. ( 26271350 )
2015
11
A Novel Technique for Repair of Complete Atrioventricular Canal Defect: The Central Patch Technique. ( 24958047 )
2014
12
A Rare Case of Pulmonary Artery Sling and Complete Atrioventricular Canal Defect in an Infant With Trisomy 21. ( 24958055 )
2014
13
Fetal complete common atrioventricular canal defect: spontaneous closure of the ventricular septal defect--in utero anatomic evolution and postnatal outcomes. ( 23799731 )
2013
14
Noonan syndrome with complete atrioventricular canal defect with pulmonary stenosis. ( 24055746 )
2013
15
Changes in left atrioventricular valve geometry after surgical repair of complete atrioventricular canal. ( 22078711 )
2012
16
Anesthesia for an infant with Beckwith-Wiedman syndrome who underwent open heart surgery for complete atrioventricular canal defect. ( 25631696 )
2012
17
Descriptive epidemiology of non-syndromic complete atrioventricular canal defects. ( 23061687 )
2012
18
Improving left ventricular outflow tract obstruction repair in common atrioventricular canal defects. ( 22626757 )
2012
19
Outcome after two-patch repair of complete common atrioventricular canal defects in patients weighing four kilograms or less. ( 23804859 )
2012
20
Complete atrioventricular canal with guarded primum septal defect. ( 21188369 )
2011
21
Prolonged QT in a 13-year-old patient with Down syndrome and complete atrioventricular canal defect. ( 22008496 )
2011
22
Individualized approach to repair of complete atrioventricular canal: selective use of the traditional single-patch technique versus the Australian technique. ( 23804726 )
2010
23
No-patch technique for complete atrioventricular canal repair. ( 20609816 )
2010
24
Complete atrioventricular canal in a dog. ( 20615778 )
2010
25
Management of complete atrioventricular canal defect with aortic arch obstruction: an unresolved debate. ( 23804821 )
2010
26
Complete atrioventricular canal repair under 1 year: Rastelli one-patch procedure yields excellent long-term results. ( 19049757 )
2008
27
Prenatal diagnosis of complete atrioventricular canal associated with tetralogy of Fallot. ( 17663460 )
2008
28
Traditional single patch versus the "Australian" technique for repair of complete atrioventricular canal defects. ( 18958557 )
2008
29
Echocardiographic evaluation and surgical implications of common atrioventricular canal defects with absent or diminutive ostium primum defect. ( 18489945 )
2008
30
Overview: history, anatomy, timing, and results of complete atrioventricular canal. ( 17433985 )
2007
31
Primary repair of d-transposition with complete atrioventricular canal defect. ( 17244905 )
2007
32
Complete atrioventricular canal: comparison of modified single-patch technique with two-patch technique. ( 18036931 )
2007
33
What is the best technique for repair of complete atrioventricular canal? ( 17983953 )
2007
34
Common atrioventricular canal in a newborn foal--case report and review of the literature. ( 17385556 )
2007
35
Analysis of surgical outcome in complex double-outlet right ventricle with heterotaxy syndrome or complete atrioventricular canal defect. ( 16798205 )
2006
36
No patch technique for complete atrioventricular canal repair. ( 17670589 )
2006
37
Complete atrioventricular canal. ( 16722604 )
2006
38
No patch technique for complete atrioventricular canal repair. ( 17670590 )
2006
39
Biventricular repair of right-dominant complete atrioventricular canal defect. ( 17072673 )
2006
40
Complete atrioventricular canal defect in a foal: Clinical and pathological features. ( 19083319 )
2005
41
Biventricular repair of complete atrioventricular canal, double-outlet right ventricle and common atrium using a modified double switch technique. A valid alternative to univentricular procedure. ( 17670392 )
2005
42
[Infections as a preoperative problem in patients with tetralogy of Fallot (TOF) associated with complete atrioventricular canal septal defect (AVC)]. ( 15724657 )
2004
43
Complete atrioventricular canal and tetralogy of Fallot with pulmonary atresia. ( 15464457 )
2004
44
Complete endocardial cushion defect (complete atrioventricular canal) manifested in adult life by Streptococcus mitis endocarditis of the common atrioventricular valve. ( 12727016 )
2003
45
One-stage repair of complete atrioventricular canal, double-outlet right ventricle, left superior vena cava, cor triatriatum and pulmonary stenosis. ( 12537251 )
2003
46
Play safe: band the late presenting complete atrioventricular canal. ( 12079967 )
2002
47
Single-stage anatomical repair of complete atrioventricular canal, double-outlet right ventricle, and cor triatriatum using ventricular septal defect translocation. ( 11996287 )
2002
48
Macroreentrant atrial flutter around a common atrioventricular canal in an infant with complicated congenital heart anomaly. ( 12418755 )
2002
49
Unusual association of hypertrophic cardiomyopathy with complete atrioventricular canal defect and Down syndrome. ( 11093415 )
2000
50
Surgery of the complete atrioventricular canal: relationship between age at operation, mitral regurgitation, size of the ventricular septum defect, additional malformations and early postoperative outcome. ( 10545678 )
1999

Variations for Complete Atrioventricular Canal

Expression for Complete Atrioventricular Canal

Search GEO for disease gene expression data for Complete Atrioventricular Canal.

Pathways for Complete Atrioventricular Canal

GO Terms for Complete Atrioventricular Canal

Sources for Complete Atrioventricular Canal

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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