MCID: CNG004
MIFTS: 41

Congenital Epulis

Categories: Cancer diseases, Oral diseases, Rare diseases

Aliases & Classifications for Congenital Epulis

MalaCards integrated aliases for Congenital Epulis:

Name: Congenital Epulis 12 60 15
Gingival Neoplasms 45 74
Congenital Granular Cell Tumor 60
Congenital Gingival Cell Tumor 60
Congenital Epulides 12
Neumann Tumor 60

Characteristics:

Orphanet epidemiological data:

60
congenital epulis
Age of onset: Infancy,Neonatal;

Classifications:



External Ids:

Disease Ontology 12 DOID:7280
MeSH 45 D005887
NCIt 51 C4675
SNOMED-CT 69 25511009
ICD10 via Orphanet 35 K06.8
UMLS via Orphanet 75 C0376319
Orphanet 60 ORPHA157826

Summaries for Congenital Epulis

MalaCards based summary : Congenital Epulis, also known as gingival neoplasms, is related to epulis and granular cell tumor. An important gene associated with Congenital Epulis is DES (Desmin), and among its related pathways/superpathways are NF-kappaB Signaling and ECM-receptor interaction. Affiliated tissues include tongue, liver and breast, and related phenotypes are behavior/neurological and cellular

Wikipedia : 77 Congenital epulis is a proliferation of cells most frequently occurring on the alveolar ridge of the... more...

Related Diseases for Congenital Epulis

Diseases in the Epulis family:

Congenital Epulis

Diseases related to Congenital Epulis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 140)
# Related Disease Score Top Affiliating Genes
1 epulis 31.6 DES ENO2 NGFR PGR VIM
2 granular cell tumor 30.3 CD68 DES ENO2 UCHL1 VIM
3 infantile digital fibromatosis 10.5 DES VIM
4 angiolipoma 10.5 DES VIM
5 spindle cell lipoma 10.5 DES VIM
6 parachordoma 10.4 DES VIM
7 malignant ectomesenchymoma 10.4 DES ENO2
8 syringocystadenoma papilliferum 10.4 DES VIM
9 ectomesenchymoma 10.4 DES ENO2
10 bednar tumor 10.4 ENO2 VIM
11 papillary tumor of the pineal region 10.4 ENO2 VIM
12 benign breast phyllodes tumor 10.4 PGR VIM
13 endometrial mucinous adenocarcinoma 10.4 PGR VIM
14 biphasic synovial sarcoma 10.4 DES VIM
15 clear cell ependymoma 10.4 ENO2 VIM
16 clear cell meningioma 10.4 PGR VIM
17 astroblastoma 10.4 ENO2 VIM
18 syringoma 10.4 DES VIM
19 lymphangiomatosis 10.4 DES PGR VIM
20 juvenile xanthogranuloma 10.4 DES VIM
21 melanotic neuroectodermal tumor 10.4 ENO2 VIM
22 benign metastasizing leiomyoma 10.4 DES PGR VIM
23 cystic nephroma 10.4 DES PGR VIM
24 perivascular epithelioid cell tumor 10.4 DES PGR VIM
25 smooth muscle tumor 10.4 DES PGR VIM
26 primitive neuroectodermal tumor of the cervix uteri 10.4 DES ENO2 VIM
27 ossifying fibromyxoid tumor 10.3 DES ENO2 VIM
28 epithelioid leiomyosarcoma 10.3 DES ENO2 VIM
29 spindle cell carcinoma 10.3 DES PGR VIM
30 cauda equina neoplasm 10.3 ENO2 UCHL1
31 desmoplastic small round cell tumor 10.3 DES ENO2 VIM
32 extraskeletal ewing sarcoma 10.3 DES ENO2 VIM
33 glomus tumor 10.3 DES ENO2 VIM
34 carcinosarcoma 10.3 DES PGR VIM
35 pleomorphic liposarcoma 10.3 DES VIM
36 cervical clear cell adenocarcinoma 10.3 ENO2 PGR
37 endometrial stromal sarcoma 10.3 DES PGR VIM
38 alveolar soft part sarcoma 10.3 DES ENO2 VIM
39 cutaneous fibrous histiocytoma 10.3 DES HAVCR1 VIM
40 pulmonary vein stenosis 10.3 DES PECAM1
41 congenital fibrosarcoma 10.3 DES VIM
42 prostate stromal sarcoma 10.3 CD34 PGR
43 trigonitis 10.3 CD34 PGR
44 vulvar dystrophy 10.3 CD34 PGR
45 hemangiopericytoma, malignant 10.3 DES NGFR VIM
46 gallbladder sarcoma 10.3 CD34 DES
47 glomangiomyoma 10.3 CD34 VIM
48 angiomyoma 10.3 CD34 ENO2
49 cavernous hemangioma 10.3 DES PECAM1 VIM
50 adenosarcoma 10.3 DES PGR

Graphical network of the top 20 diseases related to Congenital Epulis:



Diseases related to Congenital Epulis

Symptoms & Phenotypes for Congenital Epulis

MGI Mouse Phenotypes related to Congenital Epulis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.1 CD44 DES ENO2 ITGA5 LIPE NGFR
2 cellular MP:0005384 10.06 CD34 CD44 DES ENO2 ITGA5 LIPE
3 cardiovascular system MP:0005385 10.02 CD44 DES ITGA5 LIPE NGFR PECAM1
4 hematopoietic system MP:0005397 9.91 CD34 CD44 CD68 NGFR PECAM1 PGR
5 homeostasis/metabolism MP:0005376 9.9 CD34 CD44 DES LIPE NGFR PECAM1
6 immune system MP:0005387 9.61 CD34 CD44 CD68 ITGA5 NGFR PECAM1
7 muscle MP:0005369 9.17 CD44 DES LIPE NGFR PECAM1 PGR

Drugs & Therapeutics for Congenital Epulis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-Making Recruiting NCT03239834

Search NIH Clinical Center for Congenital Epulis

Cochrane evidence based reviews: gingival neoplasms

Genetic Tests for Congenital Epulis

Anatomical Context for Congenital Epulis

MalaCards organs/tissues related to Congenital Epulis:

42
Tongue, Liver, Breast, Skin, Lung, Prostate, Testes

Publications for Congenital Epulis

Articles related to Congenital Epulis:

(show top 50) (show all 143)
# Title Authors Year
1
Congenital epulis: a rare case of feeding obstruction in a neonate. ( 31031062 )
2019
2
Congenital Epulis: A Case and Review of the Literature. ( 29962420 )
2018
3
Prenatal Diagnosis of Congenital Epulis: Implications for Delivery. ( 28026880 )
2017
4
Congenital Epulis. ( 26933472 )
2016
5
Two variations of congenital epulis. ( 27280469 )
2016
6
Congenital epulis: A rare benign tumour. ( 28064302 )
2016
7
Two- and three-dimensional ultrasound for assessing potential airway obstruction in congenital epulis. ( 25487070 )
2015
8
Congenital Epulis: A Rare Benign Jaw Tumour in a 2-Day-Old Male Baby. ( 26379808 )
2015
9
Congenital epulis of the newborn. ( 26980979 )
2015
10
Congenital epulis. ( 23896792 )
2014
11
Multiple congenital epulis in alveolar ridges of maxilla and mandible in a newborn: a rare case report. ( 24808964 )
2014
12
Congenital epulis: from birth to childhood. ( 24827956 )
2014
13
Congenital epulis in a newborn. ( 24941588 )
2014
14
Twin congenital epulis in the alveolar ridge of the maxilla and mandible in a newborn: a rare and interesting case. ( 25199202 )
2014
15
Congenital epulis in a newborn: a case report, immunoprofiling and review of literature. ( 25489201 )
2014
16
Congenital epulis of the newborn: difficult to diagnose but easy to treat. A case of unusual size. ( 25600926 )
2014
17
Congenital Epulis: a clinical case presentation. ( 28191214 )
2014
18
Prenatal diagnosis of congenital epulis by 2D/3D ultrasound and magnetic resonance. ( 23548590 )
2013
19
Spontaneous regression of a congenital epulis in a newborn. ( 23855175 )
2013
20
Congenital epulis. ( 22237195 )
2012
21
Congenital epulis in newborn. Case report. ( 22474798 )
2012
22
Epidermal choristoma arising on the midline gingiva as a congenital epulis: a case report. ( 22487269 )
2012
23
Congenital epulis. ( 22778448 )
2012
24
Multiple congenital epulis of the mandibular ridge: a case report. ( 24303409 )
2012
25
Anesthetic management of congenital epulis in neonate. ( 25885516 )
2012
26
Congenital epulis: a rare benign jaw tumor of newborn. ( 26023390 )
2012
27
Congenital epulis of the newborn: 10 new cases of a rare oral tumor. ( 21393037 )
2011
28
Prenatal sonographic diagnosis of congenital epulis. ( 21480287 )
2011
29
Leiomyomatous hamartoma of the midline maxillary gingival presenting as a congenital epulis: a case report with an immunohistochemical study. ( 21696920 )
2011
30
Congenital epulis of the tongue: A case report and review of the literature. ( 21847444 )
2011
31
Gingival mass. Congenital epulis. ( 20591782 )
2010
32
Congenital epulis. ( 20628985 )
2010
33
Congenital epulis. ( 20657103 )
2010
34
Obstructive congenital epulis. ( 20822763 )
2010
35
Spontaneous regression of congenital epulis: a case report and review of the literature. ( 20964807 )
2010
36
Congenital epulis: a rare benign tumor in the newborn. ( 21157060 )
2010
37
Congenital epulis of the jaw: a series of five cases and review of literature. ( 19082830 )
2009
38
Congenital epulis in the newborn, review of the literature and a case report. ( 19262247 )
2009
39
Atypical presentation of congenital epulis: case report and review of the literature. ( 19442358 )
2009
40
Congenital epulis of the newborn. ( 19679987 )
2009
41
Congenital epulis: a case report and estimation of incidence. ( 20130770 )
2009
42
Multiple congenital epulis in newborn - A rare presentation. ( 21887006 )
2009
43
Anaesthesia for excision of an intraoral mass in a neonate: use of a laryngeal mask during removal of congenital epulis. ( 18326145 )
2008
44
Congenital epulis: prenatal ultrasonographic and postnatal MR features with pathologic correlation. ( 18424116 )
2008
45
Neonatal oral tumors: congenital epulis and epignathus. ( 18778989 )
2008
46
Congenital epulis. A case report. ( 18811099 )
2008
47
Congenital epulis: an unusual case of spontaneous regression. ( 21444268 )
2008
48
Congenital epulis of the newborn: a case report. ( 17508069 )
2007
49
Complete spontaneous regression of congenital epulis in a baby by 8 months of age. ( 17559460 )
2007
50
Congenital epulis of the newborn: a case report with review of literature. ( 17883149 )
2007

Variations for Congenital Epulis

Expression for Congenital Epulis

Search GEO for disease gene expression data for Congenital Epulis.

Pathways for Congenital Epulis

GO Terms for Congenital Epulis

Cellular components related to Congenital Epulis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.8 CD34 CD44 CD68 CEACAM5 DES ENO2
2 cell surface GO:0009986 9.55 CD34 CD44 CEACAM5 ITGA5 NGFR
3 plasma membrane GO:0005886 9.44 CD34 CD44 CD68 CEACAM5 DES ENO2

Biological processes related to Congenital Epulis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell adhesion GO:0007155 9.65 CD34 CD44 CEACAM5 ITGA5 PECAM1
2 intermediate filament organization GO:0045109 9.37 DES VIM
3 negative regulation of anoikis GO:2000811 9.32 CEACAM5 ITGA5
4 paracrine signaling GO:0038001 9.16 CD34 PGR
5 leukocyte migration GO:0050900 9.02 CD34 CD44 CEACAM5 ITGA5 PECAM1
6 glomerular endothelium development GO:0072011 8.96 CD34 PECAM1

Sources for Congenital Epulis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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