MCID: CNG004
MIFTS: 40

Congenital Epulis

Categories: Cancer diseases, Oral diseases, Rare diseases

Aliases & Classifications for Congenital Epulis

MalaCards integrated aliases for Congenital Epulis:

Name: Congenital Epulis 12 59 15
Gingival Neoplasms 44 73
Congenital Granular Cell Tumor 59
Congenital Gingival Cell Tumor 59
Congenital Epulides 12
Neumann Tumor 59

Characteristics:

Orphanet epidemiological data:

59
congenital epulis
Age of onset: Infancy,Neonatal;

Classifications:



External Ids:

Disease Ontology 12 DOID:7280
MeSH 44 D005887
NCIt 50 C4675
SNOMED-CT 68 25511009
Orphanet 59 ORPHA157826
ICD10 via Orphanet 34 K06.8
UMLS via Orphanet 74 C0376319

Summaries for Congenital Epulis

MalaCards based summary : Congenital Epulis, also known as gingival neoplasms, is related to epulis and congenital granular cell tumor. An important gene associated with Congenital Epulis is DES (Desmin), and among its related pathways/superpathways are NF-kappaB Signaling and Adhesion. Affiliated tissues include skin, liver and breast, and related phenotypes are behavior/neurological and cellular

Related Diseases for Congenital Epulis

Diseases in the Epulis family:

Congenital Epulis

Diseases related to Congenital Epulis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 156)
# Related Disease Score Top Affiliating Genes
1 epulis 31.6 DES ENO2 NGFR PGR VIM
2 congenital granular cell tumor 30.5 ENO2 LYZ
3 granular cell tumor 30.5 CD68 DES ENO2 UCHL1 VIM
4 infantile digital fibromatosis 10.3 DES VIM
5 angiolipoma 10.3 DES VIM
6 cutaneous leiomyosarcoma 10.3 DES VIM
7 bednar tumor 10.3 ENO2 VIM
8 spindle cell lipoma 10.3 DES VIM
9 parachordoma 10.3 DES VIM
10 syringocystadenoma papilliferum 10.3 DES VIM
11 malignant ectomesenchymoma 10.3 DES ENO2
12 ectomesenchymoma 10.3 DES ENO2
13 papillary tumor of the pineal region 10.3 ENO2 VIM
14 benign breast phyllodes tumor 10.3 PGR VIM
15 endometrial mucinous adenocarcinoma 10.3 PGR VIM
16 clear cell ependymoma 10.3 ENO2 VIM
17 biphasic synovial sarcoma 10.3 DES VIM
18 lymphangiomatosis 10.3 DES PGR VIM
19 benign metastasizing leiomyoma 10.3 DES PGR VIM
20 primitive neuroectodermal tumor of the cervix uteri 10.3 DES ENO2 VIM
21 cystic nephroma 10.3 DES PGR VIM
22 auditory system cancer 10.3 ENO2 LYZ
23 ossifying fibromyxoid tumor 10.3 DES ENO2 VIM
24 epithelioid leiomyosarcoma 10.3 DES ENO2 VIM
25 perivascular epithelioid cell tumor 10.3 DES PGR VIM
26 desmoplastic small round cell tumor 10.3 DES ENO2 VIM
27 smooth muscle tumor 10.3 DES PGR VIM
28 extraskeletal ewing sarcoma 10.3 DES ENO2 VIM
29 glomus tumor 10.3 DES ENO2 VIM
30 spindle cell carcinoma 10.3 DES PGR VIM
31 carcinosarcoma 10.3 DES PGR VIM
32 clear cell meningioma 10.3 PGR VIM
33 sensory organ benign neoplasm 10.2 ENO2 LYZ
34 alveolar soft part sarcoma 10.2 DES ENO2 VIM
35 cutaneous fibrous histiocytoma 10.2 DES HAVCR1 VIM
36 adenoid squamous cell carcinoma 10.2 HBA1 VIM
37 endometrial stromal sarcoma 10.2 DES PGR VIM
38 cauda equina neoplasm 10.2 ENO2 UCHL1
39 astroblastoma 10.2 ENO2 VIM
40 juvenile xanthogranuloma 10.2 DES LYZ VIM
41 malignant fibroxanthoma 10.2 DES LYZ VIM
42 prostate stromal sarcoma 10.2 CD34 PGR
43 neurogenic arthropathy 10.2 HBA1 NGFR
44 glomangiomyoma 10.2 CD34 VIM
45 trigonitis 10.2 CD34 PGR
46 vulvar dystrophy 10.2 CD34 PGR
47 pericardial mesothelioma 10.2 ENO2 HBA1 VIM
48 dermis tumor 10.2 HAVCR1 LYZ
49 gallbladder sarcoma 10.2 CD34 DES
50 cerebral primitive neuroectodermal tumor 10.2 CD44 ENO2 VIM

Graphical network of the top 20 diseases related to Congenital Epulis:



Diseases related to Congenital Epulis

Symptoms & Phenotypes for Congenital Epulis

MGI Mouse Phenotypes related to Congenital Epulis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.18 AVPR2 CD44 DES ENO2 ITGA5 LIPE
2 cellular MP:0005384 10.1 CD34 CD44 DES ENO2 ITGA5 LIPE
3 cardiovascular system MP:0005385 10.02 CD44 DES ITGA5 LIPE LYZ NGFR
4 hematopoietic system MP:0005397 9.96 AVPR2 CD34 CD44 CD68 LYZ NGFR
5 homeostasis/metabolism MP:0005376 9.93 AVPR2 CD34 CD44 DES LIPE LYZ
6 immune system MP:0005387 9.65 CD34 CD44 CD68 ITGA5 LYZ NGFR
7 integument MP:0010771 9.23 AVPR2 CD34 CD44 LIPE LYZ NGFR

Drugs & Therapeutics for Congenital Epulis

Search Clinical Trials , NIH Clinical Center for Congenital Epulis

Cochrane evidence based reviews: gingival neoplasms

Genetic Tests for Congenital Epulis

Anatomical Context for Congenital Epulis

MalaCards organs/tissues related to Congenital Epulis:

41
Skin, Liver, Breast, Ovary, Spleen, Prostate, Testis

Publications for Congenital Epulis

Articles related to Congenital Epulis:

(show top 50) (show all 140)
# Title Authors Year
1
Congenital Epulis: A Case and Review of the Literature. ( 29962420 )
2018
2
Prenatal Diagnosis of Congenital Epulis: Implications for Delivery. ( 28026880 )
2017
3
Two variations of congenital epulis. ( 27280469 )
2016
4
Congenital epulis: A rare benign tumour. ( 28064302 )
2016
5
Congenital Epulis. ( 26933472 )
2016
6
Congenital Epulis: A Rare Benign Jaw Tumour in a 2-Day-Old Male Baby. ( 26379808 )
2015
7
Congenital epulis of the newborn. ( 26980979 )
2015
8
Twin congenital epulis in the alveolar ridge of the maxilla and mandible in a newborn: a rare and interesting case. ( 25199202 )
2014
9
Congenital epulis in a newborn: a case report, immunoprofiling and review of literature. ( 25489201 )
2014
10
Congenital epulis of the newborn: difficult to diagnose but easy to treat A case of unusual size. ( 25600926 )
2014
11
Relevance of fetal 2D/3D ultrasonography for assessing potential airway obstruction in congenital epulis. ( 25487070 )
2014
12
Congenital Epulis: a clinical case presentation. ( 28191214 )
2014
13
Congenital epulis: from birth to childhood. ( 24827956 )
2014
14
Multiple congenital epulis in alveolar ridges of maxilla and mandible in a newborn: a rare case report. ( 24808964 )
2014
15
Congenital epulis in a newborn. ( 24941588 )
2014
16
Spontaneous regression of a congenital epulis in a newborn. ( 23855175 )
2013
17
Congenital epulis. ( 23896792 )
2013
18
Prenatal diagnosis of congenital epulis by 2D/3D ultrasound and magnetic resonance. ( 23548590 )
2013
19
Congenital epulis. ( 22778448 )
2012
20
Multiple congenital epulis of the mandibular ridge: a case report. ( 24303409 )
2012
21
Congenital epulis. ( 22237195 )
2012
22
Congenital epulis in newborn. Case report. ( 22474798 )
2012
23
Anesthetic management of congenital epulis in neonate. ( 25885516 )
2012
24
Congenital epulis: a rare benign jaw tumor of newborn. ( 26023390 )
2012
25
Epidermal choristoma arising on the midline gingiva as a congenital epulis: a case report. ( 22487269 )
2012
26
Congenital epulis of the tongue: A case report and review of the literature. ( 21847444 )
2011
27
Leiomyomatous hamartoma of the midline maxillary gingival presenting as a congenital epulis: a case report with an immunohistochemical study. ( 21696920 )
2011
28
Prenatal sonographic diagnosis of congenital epulis. ( 21480287 )
2011
29
Congenital epulis of the newborn: 10 new cases of a rare oral tumor. ( 21393037 )
2011
30
Congenital epulis: a rare benign tumor in the newborn. ( 21157060 )
2010
31
Congenital epulis. ( 20657103 )
2010
32
Congenital epulis. ( 20628985 )
2010
33
Obstructive congenital epulis. ( 20822763 )
2010
34
Gingival mass. Congenital epulis. ( 20591782 )
2010
35
Spontaneous regression of congenital epulis: a case report and review of the literature. ( 20964807 )
2010
36
Congenital epulis: a case report and estimation of incidence. ( 20130770 )
2009
37
Congenital epulis in the newborn, review of the literature and a case report. ( 19262247 )
2009
38
Atypical presentation of congenital epulis: case report and review of the literature. ( 19442358 )
2009
39
Multiple congenital epulis in newborn - A rare presentation. ( 21887006 )
2009
40
Congenital epulis of the newborn. ( 19679987 )
2009
41
Congenital epulis of the jaw: a series of five cases and review of literature. ( 19082830 )
2009
42
Anaesthesia for excision of an intraoral mass in a neonate: use of a laryngeal mask during removal of congenital epulis. ( 18326145 )
2008
43
Congenital epulis. A case report. ( 18811099 )
2008
44
Congenital epulis: an unusual case of spontaneous regression. ( 21444268 )
2008
45
Neonatal oral tumors: congenital epulis and epignathus. ( 18778989 )
2008
46
Congenital epulis: prenatal ultrasonographic and postnatal MR features with pathologic correlation. ( 18424116 )
2008
47
Treatment of congenital epulis (granular cell tumour) with excision and gingivoperiosteoplasty. ( 19554180 )
2007
48
Complete spontaneous regression of congenital epulis in a baby by 8 months of age. ( 17559460 )
2007
49
Congenital epulis of the newborn: a case report with review of literature. ( 17883149 )
2007
50
Congenital epulis. ( 18326351 )
2007

Variations for Congenital Epulis

Expression for Congenital Epulis

Search GEO for disease gene expression data for Congenital Epulis.

Pathways for Congenital Epulis

Pathways related to Congenital Epulis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.97 CD34 CD44 CEACAM5 HAVCR1
2 11.52 CD44 CEACAM5 ITGA5
3 11.12 CD34 CD44 ITGA5
4 10.99 CD34 CD44 CD68 CEACAM5

GO Terms for Congenital Epulis

Cellular components related to Congenital Epulis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosol GO:0005829 9.93 CD44 DES ENO2 HBA1 LIPE NGFR
2 extracellular exosome GO:0070062 9.92 CD44 CEACAM5 DES ENO2 HBA1 LYZ
3 membrane GO:0016020 9.83 AVPR2 CD34 CD44 CD68 CEACAM5 DES
4 cell surface GO:0009986 9.65 CD34 CD44 CEACAM5 ITGA5 NGFR
5 plasma membrane GO:0005886 9.44 AVPR2 CD34 CD44 CD68 CEACAM5 DES

Biological processes related to Congenital Epulis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament organization GO:0045109 9.26 DES VIM
2 negative regulation of anoikis GO:2000811 9.16 CEACAM5 ITGA5
3 paracrine signaling GO:0038001 8.96 CD34 PGR
4 leukocyte migration GO:0050900 8.92 CD34 CD44 CEACAM5 ITGA5

Sources for Congenital Epulis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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