MCID: CNG241
MIFTS: 13

Congenital Laryngeal Palsy

Categories: Fetal diseases, Neuronal diseases, Oral diseases, Rare diseases

Aliases & Classifications for Congenital Laryngeal Palsy

MalaCards integrated aliases for Congenital Laryngeal Palsy:

Name: Congenital Laryngeal Palsy 52 58
Congenital Vocal Cord Paralysis 52 58

Classifications:

Orphanet: 58  
Rare neurological diseases
Rare otorhinolaryngological diseases
Developmental anomalies during embryogenesis


External Ids:

ICD10 via Orphanet 33 J38.0
UMLS via Orphanet 72 C0396058
Orphanet 58 ORPHA137932

Summaries for Congenital Laryngeal Palsy

NIH Rare Diseases : 52 Congenital laryngeal palsy is also known as congenital vocal cord paralysis. It represents 15%-20% of all cases of congenital anomalies of the larynx. It may affect one (unilateral) or both (bilateral) vocal cords. The cause of bilateral paralysis of the vocal cords is often unknown (idiopathic). In some cases, paralysis may be secondary to the immaturity of the nerve or muscle (neuromuscular) or due to central nervous system damage (including the Arnold-Chiari malformation , cerebral palsy , hydrocephalus , myelomeningocele , spina bifida , hypoxia (lack of oxygen in the blood), or bleeding). Birth trauma that causes excessive tension in the neck can cause transient bilateral vocal cord paralysis that can last 6-9 months. Unilateral paralysis is usually idiopathic but can be secondary to problems with the vagus nerve or recurrent laryngeal nerve trauma. The signs and symptoms of bilateral vocal fold paralysis may include making a noise when breathing (inspiratory stridor) that worsens upon exercise, progressive obstruction of the respiratory airway, aspiration, recurrent chest infections, cyanosis , nose flaring and signs of cranial nerve deficits during the head and neck exam. Flexible endoscopy can be used to diagnose the condition. Treatment may include medication, surgery, and speech therapy.

MalaCards based summary : Congenital Laryngeal Palsy, also known as congenital vocal cord paralysis, is related to laryngomalacia and chiari malformation type ii.

Related Diseases for Congenital Laryngeal Palsy

Diseases related to Congenital Laryngeal Palsy via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 laryngomalacia 10.2
2 chiari malformation type ii 10.2
3 chiari malformation 10.2
4 ptosis 10.0
5 cardiac arrest 10.0
6 congenital myasthenic syndrome 10.0
7 bronchitis 10.0
8 hypotonia 10.0

Graphical network of the top 20 diseases related to Congenital Laryngeal Palsy:



Diseases related to Congenital Laryngeal Palsy

Symptoms & Phenotypes for Congenital Laryngeal Palsy

Drugs & Therapeutics for Congenital Laryngeal Palsy

Search Clinical Trials , NIH Clinical Center for Congenital Laryngeal Palsy

Genetic Tests for Congenital Laryngeal Palsy

Anatomical Context for Congenital Laryngeal Palsy

Publications for Congenital Laryngeal Palsy

Articles related to Congenital Laryngeal Palsy:

# Title Authors PMID Year
1
Congenital Vocal Cord Paralysis and Late-Onset Limb-Girdle Weakness in MuSK-Congenital Myasthenic Syndrome. 61
31920924 2019
2
Familial impairment of vocal cord mobility in childhood with clubfoot. 61
29912011 2018
3
Congenital vocal cord paralysis. 61
20098198 2010
4
Applications of flexible bronchoscopy in infants with congenital vocal cord paralysis: a 12-year experience. 61
19133570 2008
5
Bilateral congenital vocal cord paralysis: a 16-year institutional review. 61
16087022 2005
6
Humans are born too soon: impact on pediatric otolaryngology. 61
15627440 2005
7
Respiratory distress in a pregnant woman with congenital vocal cord paralysis. 61
12423811 2002
8
Congenital vocal cord paralysis with possible autosomal recessive inheritance: case report and review of the literature. 61
8862626 1996
9
Outcome of laryngeal paralysis in neonates: a long term retrospective study of 113 cases. 61
8770677 1996
10
Systemic gas embolus: a discussion of its pathogenesis in the neonate, with a review of the literature. 61
900088 1977

Variations for Congenital Laryngeal Palsy

Expression for Congenital Laryngeal Palsy

Search GEO for disease gene expression data for Congenital Laryngeal Palsy.

Pathways for Congenital Laryngeal Palsy

GO Terms for Congenital Laryngeal Palsy

Sources for Congenital Laryngeal Palsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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