MCID: CNG133
MIFTS: 29

Congenital Varicella Syndrome

Categories: Eye diseases, Fetal diseases, Infectious diseases, Neuronal diseases, Rare diseases, Skin diseases

Aliases & Classifications for Congenital Varicella Syndrome

MalaCards integrated aliases for Congenital Varicella Syndrome:

Name: Congenital Varicella Syndrome 54 60 74
Mother-to-Child Transmission of Varicella Syndrome 60
Fetal Effects of Varicella Zoster Virus 54
Varicella Virus Antenatal Infection 54
Antenatal Varicella Virus Infection 60
Fetal Varicella Zoster Syndrome 54
Fetal Effects of Chickenpox 54
Fetal Varicella Infection 54
Varicella Embryopathy 54

Characteristics:

Orphanet epidemiological data:

60
congenital varicella syndrome
Inheritance: Not applicable; Age of onset: Antenatal,Neonatal;

Classifications:



Summaries for Congenital Varicella Syndrome

NIH Rare Diseases : 54 Congenital varicella syndrome is an extremely rare disorder in which affected infants have distinctive abnormalities at birth  due to the mother's infection with chickenpox (maternal varicella zoster) early during pregnancy (i.e., up to 20 weeks gestation). Affected newborns may have a low birth weight and characteristic abnormalities of the skin, brain, eyes, the arms, legs, hands, and/or feet, and/or, in rare cases, other areas of the body. The range and severity of associated symptoms and physical findings may vary greatly from case to case depending upon when maternal varicella zoster infection occurred during fetal development.

MalaCards based summary : Congenital Varicella Syndrome, also known as mother-to-child transmission of varicella syndrome, is related to hydrocephalus and heart disease. Affiliated tissues include skin, brain and eye, and related phenotypes are intrauterine growth retardation and atypical scarring of skin

Wikipedia : 77 Chickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with... more...

Related Diseases for Congenital Varicella Syndrome

Diseases in the Varicella, Severe Recurrent family:

Congenital Varicella Syndrome

Diseases related to Congenital Varicella Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hydrocephalus 9.8
2 heart disease 9.8
3 hypertensive heart disease 9.8
4 chickenpox 9.8
5 renal dysplasia 9.8

Graphical network of the top 20 diseases related to Congenital Varicella Syndrome:



Diseases related to Congenital Varicella Syndrome

Symptoms & Phenotypes for Congenital Varicella Syndrome

Human phenotypes related to Congenital Varicella Syndrome:

60 33 (show all 9)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 intrauterine growth retardation 60 33 hallmark (90%) Very frequent (99-80%) HP:0001511
2 atypical scarring of skin 60 33 hallmark (90%) Very frequent (99-80%) HP:0000987
3 intellectual disability 60 33 frequent (33%) Frequent (79-30%) HP:0001249
4 cataract 60 33 frequent (33%) Frequent (79-30%) HP:0000518
5 global developmental delay 60 33 frequent (33%) Frequent (79-30%) HP:0001263
6 microcephaly 60 33 frequent (33%) Frequent (79-30%) HP:0000252
7 micromelia 60 33 frequent (33%) Frequent (79-30%) HP:0002983
8 cerebral cortical atrophy 60 33 frequent (33%) Frequent (79-30%) HP:0002120
9 microphthalmia 60 33 frequent (33%) Frequent (79-30%) HP:0000568

Drugs & Therapeutics for Congenital Varicella Syndrome

Search Clinical Trials , NIH Clinical Center for Congenital Varicella Syndrome

Genetic Tests for Congenital Varicella Syndrome

Anatomical Context for Congenital Varicella Syndrome

MalaCards organs/tissues related to Congenital Varicella Syndrome:

42
Skin, Brain, Eye, Colon, Heart, Spinal Cord

Publications for Congenital Varicella Syndrome

Articles related to Congenital Varicella Syndrome:

(show top 50) (show all 55)
# Title Authors Year
1
Birth palsy in congenital varicella syndrome: A lesson in anatomy. ( 30505098 )
2018
2
Isolated lower limb hypoplasia secondary to congenital varicella syndrome: a rare occurrence and management of its complications. ( 28331020 )
2017
3
Congenital varicella syndrome: A systematic review. ( 26965725 )
2016
4
Congenital Varicella Syndrome. ( 27029702 )
2016
5
Congenital varicella syndrome in a monochorionic diamniotic twin pregnancy. ( 25097633 )
2014
6
Prenatal sonographic diagnosis of congenital varicella syndrome. ( 22323269 )
2012
7
Anesthetic implications of two genetic translocation (6p21; 6p13) in a patient with history of congenital varicella syndrome: a case report. ( 22788083 )
2012
8
Congenital varicella syndrome in a very low birthweight preterm infant. ( 21138830 )
2011
9
The prevalence of congenital varicella syndrome after a maternal infection, but before 20 weeks of pregnancy: a prospective cohort study. ( 20670093 )
2011
10
Congenital varicella syndrome: the evidence for secondary prevention with varicella-zoster immune globulin. ( 21262937 )
2011
11
Preventing congenital varicella syndrome with immunization. ( 21262940 )
2011
12
Congenital varicella syndrome/vericella zoster virus (VZV) fetopathy. ( 19936656 )
2010
13
Congenital varicella syndrome: still a problem? ( 19478488 )
2009
14
Unilateral laryngeal paralysis in a newborn with congenital varicella syndrome. ( 19054581 )
2009
15
Chronic varicella-zoster skin infection complicating the congenital varicella syndrome. ( 17845179 )
2007
16
Congenital varicella syndrome: presenting with eye complications. ( 16891691 )
2006
17
Prenatal ultrasound diagnosis, follow-up, and outcome of congenital varicella syndrome. ( 16601342 )
2006
18
Congenital varicella syndrome in the third trimester. ( 16271630 )
2005
19
Alphafoetoprotein and acetylcholinesterase in amniotic fluid as a factor suggesting fetal skin and nerve lesions in a case of congenital varicella syndrome. ( 15300737 )
2004
20
Genitourinary anomaly in congenital varicella syndrome: case report and review. ( 15015072 )
2004
21
Genitourinary anomaly in congenital varicella syndrome. ( 15221427 )
2004
22
Congenital varicella syndrome. ( 15346925 )
2004
23
Hints of intracerebral varicella-zoster virus reactivation in congenital varicella syndrome. ( 12692721 )
2003
24
Congenital varicella syndrome. ( 12619963 )
2003
25
Severe hydrocephalus associated with congenital varicella syndrome. ( 12615748 )
2003
26
Intracerebral varicella-zoster virus reactivation in congenital varicella syndrome. ( 14667077 )
2003
27
Congenital varicella syndrome with colonic atresias. ( 12862351 )
2003
28
Frequency of congenital varicella syndrome in a prospective cohort of 347 pregnant women. ( 12151147 )
2002
29
Congenital varicella syndrome: case with isolated brain damage. ( 11510932 )
2001
30
Congenital varicella syndrome as an unusual cause of congenital malformation: report of one case. ( 11550414 )
2001
31
The congenital varicella syndrome. ( 11190597 )
2000
32
Congenital varicella syndrome: a rare case of central nervous system involvement without dermatological features. ( 11110343 )
2000
33
Ipsilateral renal dysplasia with hypertensive heart disease in an infant with cutaneous varicella lesions: an unusual presentation of congenital varicella syndrome. ( 11050597 )
2000
34
Congenital varicella syndrome diagnosed by polymerase chain reaction--scarring of the spinal cord, not the skin. ( 10760023 )
2000
35
Congenital varicella syndrome in the absence of cutaneous lesions. ( 10760022 )
2000
36
Prenatal diagnosis of congenital varicella syndrome and detection of varicella-zoster virus in the fetus: a case report. ( 10215075 )
1999
37
Congenital varicella syndrome: cranial MRI in a long-term survivor. ( 10206169 )
1999
38
Congenital varicella syndrome. ( 27644722 )
1999
39
What syndrome is this? Congenital varicella syndrome. ( 8844756 )
1996
40
Detection of varicella-zoster virus in congenital varicella syndrome: a case report. ( 8841253 )
1996
41
Congenital varicella syndrome. ( 8924315 )
1995
42
Two lethal cases of congenital varicella syndrome. ( 7669392 )
1995
43
Case report 846. Congenital varicella syndrome. ( 8059264 )
1994
44
Congenital varicella syndrome: studies of the virus-specific humoral and cell-mediated immune responses. ( 7949816 )
1994
45
Prenatal diagnosis of second-trimester congenital varicella syndrome. ( 1494553 )
1992
46
Virus detection in the fetal tissue of a premature delivery with a congenital varicella syndrome. A case report. ( 2175786 )
1990
47
Ocular manifestations of the congenital varicella syndrome. ( 2910286 )
1989
48
Prenatal diagnosis of second-trimester congenital varicella syndrome by virus-specific immunoglobulin M. ( 2821214 )
1987
49
Congenital varicella syndrome. ( 3019895 )
1986
50
Picture of the month. Congenital varicella syndrome. ( 6720649 )
1984

Variations for Congenital Varicella Syndrome

Expression for Congenital Varicella Syndrome

Search GEO for disease gene expression data for Congenital Varicella Syndrome.

Pathways for Congenital Varicella Syndrome

GO Terms for Congenital Varicella Syndrome

Sources for Congenital Varicella Syndrome

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75 UMLS via Orphanet
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