MCID: CND001
MIFTS: 26

Conidiobolomycosis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Conidiobolomycosis

MalaCards integrated aliases for Conidiobolomycosis:

Name: Conidiobolomycosis 12 15
Infection by Conidiobolus 71

Classifications:



External Ids:

Disease Ontology 12 DOID:0050279
UMLS 71 C0276712

Summaries for Conidiobolomycosis

Disease Ontology : 12 An subcutaneous mycosis that is a chronic inflammatory or granulomatous fungal infection caused by Conidiobolus species, which is restricted to the nasal submucosa and characterized by polyps or palpable restricted subcutaneous masses. Symptoms include nasal obstruction, drainage and sinus pain. Subcutaneous nodules develop in the nasal and perinasal regions.

MalaCards based summary : Conidiobolomycosis, also known as infection by conidiobolus, is related to subcutaneous mycosis and mucormycosis. An important gene associated with Conidiobolomycosis is VPREB1 (V-Set Pre-B Cell Surrogate Light Chain 1), and among its related pathways/superpathways are Tamoxifen metabolism and Erlotinib Pathway, Pharmacokinetics. Affiliated tissues include skin, testes and tongue.

Wikipedia : 74 Conidiobolomycosis is a fungal... more...

Related Diseases for Conidiobolomycosis

Diseases related to Conidiobolomycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 subcutaneous mycosis 30.4 EMB CBSL B4GALNT2
2 mucormycosis 29.0 PPIG CYP51A1 CYP3A4 B4GALNT2
3 tinea pedis 10.3 CYP51A1 B4GALNT2
4 vasculitis 10.2
5 white piedra 10.1 CBSL B4GALNT2
6 tinea manuum 10.1 CBSL B4GALNT2
7 trichosporonosis 10.1 CBSL B4GALNT2
8 otomycosis 10.1 CBSL B4GALNT2
9 tracheal calcification 10.1 HEPH EPO
10 tinea unguium 10.1 CBSL B4GALNT2
11 dermatomycosis 10.1 CBSL B4GALNT2
12 phaeohyphomycosis 10.1 CBSL B4GALNT2
13 external ear disease 10.1 CBSL B4GALNT2
14 eumycotic mycetoma 10.1 LIX1 CBSL
15 otitis externa 10.1 CBSL B4GALNT2
16 sporotrichosis 10.1 EMB CBSL
17 tinea capitis 10.1 CBSL B4GALNT2
18 keratitis, hereditary 10.1
19 buruli ulcer 10.1
20 leukemia, acute lymphoblastic 10.1
21 spastic paraplegia, intellectual disability, nystagmus, and obesity 10.1
22 lymphocytic leukemia 10.1
23 orbital cellulitis 10.1
24 leukemia 10.1
25 cellulitis 10.1
26 elephantiasis 10.1
27 exophthalmos 10.1
28 hypereosinophilic syndrome 10.1
29 rare mycosis 10.1
30 lymphedema 10.1
31 tinea corporis 10.1 CBSL B4GALNT2
32 spastic paraplegia 24, autosomal recessive 10.0 CYP51A1 CBSL
33 superficial mycosis 10.0 CBSL B4GALNT2
34 dermatophytosis 10.0 CBSL B4GALNT2
35 primary systemic mycosis 9.9 EMB CBSL
36 tinea cruris 9.9 CYP51A1 CBSL B4GALNT2
37 esophageal candidiasis 9.9 CYP51A1 CYP3A4
38 acetaminophen metabolism 9.7 CYP3A4 CYP2D6
39 serotonin syndrome 9.7 CYP3A4 CYP2D6
40 clopidogrel resistance 9.6 PPIG CYP3A4
41 macular degeneration, age-related, 2 9.6 PPIG CYP3A4
42 nasopharyngitis 9.5 PPIG CYP3A4
43 hypertrophy of tongue papillae 9.4 PPIG CYP3A4 CYP2D6
44 severe cutaneous adverse reaction 9.3 PPIG CYP3A4 CYP2D6
45 sexual disorder 9.3 CYP3A4 CYP2D6
46 mycobacterium tuberculosis 1 9.2 PPIG CYP51A1 CYP3A4
47 diarrhea 9.0 PPIG CYP3A4 CYP2D6
48 hypertension, essential 8.2 PPIG EPO CYP3A4 CYP2D6 CBSL

Graphical network of the top 20 diseases related to Conidiobolomycosis:



Diseases related to Conidiobolomycosis

Symptoms & Phenotypes for Conidiobolomycosis

Drugs & Therapeutics for Conidiobolomycosis

Search Clinical Trials , NIH Clinical Center for Conidiobolomycosis

Genetic Tests for Conidiobolomycosis

Anatomical Context for Conidiobolomycosis

MalaCards organs/tissues related to Conidiobolomycosis:

40
Skin, Testes, Tongue

Publications for Conidiobolomycosis

Articles related to Conidiobolomycosis:

(show all 37)
# Title Authors PMID Year
1
Conidiobolomycosis: An Unusual Fungal Disease-Our Experience. 61
31763253 2019
2
Intranasal Rhinofacial Conidiobolomycosis (Entomophthoromycosis) With Splendore-Hoeppli Phenomenon. 61
29623742 2019
3
A Rhinofacial Conidiobolus coronatus Fungal Infection Presenting as an Intranasal Tumour. 61
30988980 2018
4
In vitro assessment of antifungal, antibacterial, and antiprotozoal drugs against clinical isolates of Conidiobolus lamprauges. 61
30289533 2018
5
Look before you leap: A case series of conidiobolomycosis from the Indian subcontinent. 61
30598971 2018
6
Experimental infection in gerbils by Conidiobolus lamprauges. 61
28258001 2017
7
Invasive Conidiobolomycosis Can Be Successfully Treated on Burn Survivors. 61
27294856 2017
8
Nasal Conidiobolomycosis- The Unknown Threat. 61
28208896 2016
9
Orofacial infection by Conidiobolus coronatus. 61
27622620 2016
10
A prospective case series evaluating efficacy and safety of combination of itraconazole and potassium iodide in rhinofacial conidiobolomycosis. 61
26234812 2016
11
Conidiobolomycosis: A case report of rare fungal infection from the eastern India. 61
26753137 2015
12
Disseminated Conidiobolus incongruus in a dog: A case report and literature review. 61
25830088 2015
13
Nasal conidiobolomycosis: a successful treatment option for localized disease. 61
25766357 2015
14
Classification of Rhinoentomophthoromycosis into Atypical, Early, Intermediate, and Late Disease: A Proposal. 61
26426120 2015
15
Interaction of Zygomycetes with innate immune cells reconsidered with respect to ecology, morphology, evolution and infection biology: a mini-review. 61
25231056 2014
16
[Rhinofacial conidiobolomycosis associated with cervical, thoracic and brachial localizations: one clinical case in Nigeria]. 61
24440611 2014
17
In vitro susceptibility of Conidiobolus lamprauges recovered from sheep to antifungal agents. 61
23958402 2013
18
Pathology of nasal infection caused by Conidiobolus lamprauges and Pythium insidiosum in sheep. 61
23375916 2013
19
Conidiobolomycosis in a young Malaysian woman showing chronic localized fibrosing leukocytoclastic vasculitis: a case report and meta-analysis focusing on clinicopathologic and therapeutic correlations with outcome. 61
22728716 2012
20
Rhinofacial conidiobolomycosis (entomophthoramycosis). 61
22682189 2012
21
Disseminated human conidiobolomycosis due to Conidiobolus lamprauges. 61
21147951 2011
22
Rhinofacial conidiobolomycosis caused by Conidiobolus coronatus in a Chinese rice farmer. 61
19422524 2010
23
Conidiobolomycosis in relapsed acute lymphoblastic leukemia. 61
19731329 2009
24
[Conidiobolomycosis, a rare fungal tumor: a case report in Ouagadougou, Burkina Faso]. 61
18431999 2008
25
Conidiobolomycosis in sheep in Brazil. 61
17491072 2007
26
Severe conidiobolomycosis complicating induction chemotherapy in a patient with acute lymphoblastic leukaemia. 61
15877726 2005
27
[Conidiobolomycosis: a case report with histophathologic findings]. 61
15678798 2004
28
Treatment of conidiobolomycosis with fluconazole in two pregnant mares. 61
15188826 2004
29
Orofacial conidiobolomycosis due to Conidiobolus incongruus. 61
12870203 2003
30
Entomophthoromycosis in Maharaj Nakorn Chiang Mai Hospital. 61
12501900 2002
31
Entomophthoromycosis in India--a 4-year study. 61
9610135 1998
32
Orbitofascial conidiobolomycosis in a child. 61
8970228 1996
33
Nasopharyngeal conidiobolomycosis in a horse. 61
8682695 1996
34
Nasofacial conidiobolomycosis. 61
1782884 1991
35
Immunodiffusion test for serodiagnosing subcutaneous zygomycosis. 61
2121787 1990
36
Surgical and medical management of rhinophycomycosis (conidiobolomycosis) in a horse. 61
3997631 1985
37
The comparative pathology of equine cutaneous phycomycosis. 61
6730223 1984

Variations for Conidiobolomycosis

Expression for Conidiobolomycosis

Search GEO for disease gene expression data for Conidiobolomycosis.

Pathways for Conidiobolomycosis

GO Terms for Conidiobolomycosis

Cellular components related to Conidiobolomycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.8 CYP51A1 CYP3A4 CYP2D6

Biological processes related to Conidiobolomycosis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 steroid metabolic process GO:0008202 9.58 CYP51A1 CYP3A4 CYP2D6
2 acute-phase response GO:0006953 9.51 IL6R EPO
3 cholesterol metabolic process GO:0008203 9.5 CYP51A1 CYP3A4 CYP2D6
4 exogenous drug catabolic process GO:0042738 9.49 CYP3A4 CYP2D6
5 drug metabolic process GO:0017144 9.48 CYP3A4 CYP2D6
6 long-chain fatty acid biosynthetic process GO:0042759 9.46 CYP3A4 CYP2D6
7 estrogen metabolic process GO:0008210 9.43 CYP3A4 CYP2D6
8 oxidative demethylation GO:0070989 9.37 CYP3A4 CYP2D6
9 heterocycle metabolic process GO:0046483 9.26 CYP3A4 CYP2D6
10 drug catabolic process GO:0042737 9.16 CYP3A4 CYP2D6
11 monoterpenoid metabolic process GO:0016098 8.96 CYP3A4 CYP2D6
12 alkaloid catabolic process GO:0009822 8.62 CYP3A4 CYP2D6

Molecular functions related to Conidiobolomycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.67 HEPH CYP51A1 CYP3A4 CYP2D6
2 iron ion binding GO:0005506 9.33 CYP51A1 CYP3A4 CYP2D6
3 steroid hydroxylase activity GO:0008395 9.32 CYP3A4 CYP2D6
4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 9.26 CYP3A4 CYP2D6
5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.13 CYP51A1 CYP3A4 CYP2D6
6 heme binding GO:0020037 8.92 CYP51A1 CYP3A4 CYP2D6 CBSL

Sources for Conidiobolomycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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