MCID: CNJ012
MIFTS: 45

Conjunctival Disease

Categories: Eye diseases, Neuronal diseases

Aliases & Classifications for Conjunctival Disease

MalaCards integrated aliases for Conjunctival Disease:

Name: Conjunctival Disease 12 15
Conjunctival Diseases 54 44 70
Conjunctival Disorder 17

Classifications:



External Ids:

Disease Ontology 12 DOID:4251
ICD9CM 34 372.9
MeSH 44 D003229
NCIt 50 C27605
SNOMED-CT 67 194583004
ICD10 32 H11.9
UMLS 70 C0009759

Summaries for Conjunctival Disease

Disease Ontology : 12 An eye disease affecting the conjunctiva, which is the mucous membrane surrounding the eye and interior of the eyelids.

MalaCards based summary : Conjunctival Disease, also known as conjunctival diseases, is related to conjunctivitis and atopic keratoconjunctivitis, and has symptoms including visual disturbance and eye manifestations. An important gene associated with Conjunctival Disease is IL4 (Interleukin 4), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Hyaluronic acid and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include eye, bone and skin, and related phenotypes are hematopoietic system and immune system

Wikipedia : 73 The conjunctiva is a tissue that lines the inside of the eyelids and covers the sclera (the white of the... more...

Related Diseases for Conjunctival Disease

Diseases related to Conjunctival Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 968)
# Related Disease Score Top Affiliating Genes
1 conjunctivitis 31.1 TNF RNASE3 NLRP3 IL6 IL5 IL4
2 atopic keratoconjunctivitis 30.7 RNASE3 IL5 IL4
3 vernal keratoconjunctivitis 30.6 RNASE3 IL5 IL4 IL13 CCL11
4 pemphigoid 30.5 TNF IL5 IL4 IL13 CCL11
5 severe cutaneous adverse reaction 30.4 TNF CRP CD8A CD4
6 erythema multiforme 30.3 TNF IL6 IL5 IL4 CXCL8
7 vernal conjunctivitis 30.3 RNASE3 IL4 CCR6
8 xerophthalmia 30.2 CRP CD8A CD4
9 trachoma 30.2 TNF IL6 IL4 IL10
10 vasculitis 30.2 TNF IL6 IFNA2 CRP
11 papillary conjunctivitis 30.1 IL6 IL4 CXCL8 CCL11
12 keratoconjunctivitis sicca 30.1 TNF IL4 CD4 CCR6 ALB
13 allergic conjunctivitis 30.1 TNF RNASE3 IL5 IL4 IL13 IL10
14 keratoconjunctivitis 30.0 TNF RNASE3 IL6 IL5 IL4 IL13
15 giant papillary conjunctivitis 29.9 RNASE3 IL6 IL4 CXCL8 CCL11
16 bacterial conjunctivitis 29.7 TNF IL6 IL1B IL10 CXCL8 CRP
17 keratitis, hereditary 29.5 TNF NLRP3 IL6 IL1B IL10 CXCL8
18 allergic disease 29.0 TNF RNASE3 IL6 IL5 IL4 IL1B
19 dermatitis 28.9 TNF RNASE3 IL6 IL5 IL4 IL1B
20 proteasome-associated autoinflammatory syndrome 1 28.9 TNF RNASE3 NLRP3 IL6 IL5 IL4
21 eye disease 28.7 TNF IL6 IL5 IL4 IL1B IL13
22 respiratory failure 28.7 TNF RNASE3 IL6 IL5 IL1B IL13
23 dermatitis, atopic 28.7 TNF RNASE3 IL6 IL5 IL4 IL1B
24 cytokine deficiency 10.5 IL5 IL13
25 geniculate ganglionitis 10.5 IFNA2 CD4
26 neurosyphilis 10.5 IL10 CXCL8
27 aztreonam allergy 10.5 IL5 IL13
28 external pathological resorption 10.5 TNF IL6
29 scorpion envenomation 10.5 TNF IL6
30 cefuroxime allergy 10.5 IL5 IL13
31 punctate inner choroidopathy 10.5 TNF IL10
32 drug reaction with eosinophilia and systemic symptoms 10.5 TNF CRP
33 necrotic uveal melanoma 10.5 CD8A CD4
34 suppurative lymphadenitis 10.5 CRP CD4 CCR6
35 riedel's fibrosing thyroiditis 10.5 CD4 ALB
36 childhood-onset asthma 10.5 RNASE3 IL13
37 blastomycosis 10.5 IL6 CD4 CCR6
38 tropical endomyocardial fibrosis 10.5 TNF IL4 IL10
39 ceftriaxone allergy 10.5 IL5 IL13 IL10
40 cow milk allergy 10.5 IL5 IL4 IL10
41 pustulosis palmaris et plantaris 10.5 TNF IL5 CCR6
42 acute asthma 10.5 RNASE3 IL5 IL4
43 cold agglutinin disease 10.5 IL6 CRP
44 hyper ige recurrent infection syndrome 1 10.5 IL6 CD4 CCR6
45 inflammatory bowel disease 18 10.5 IL4 IL10 CCR6
46 early yaws 10.5 CD8A CD4
47 panophthalmitis 10.5 CRP CD4
48 chronic duodenal ileus 10.5 CRP ALB
49 staphylococcal toxic shock syndrome 10.5 TNF IL1B
50 respiratory syncytial virus infectious disease 10.5 IL5 IL13

Graphical network of the top 20 diseases related to Conjunctival Disease:



Diseases related to Conjunctival Disease

Symptoms & Phenotypes for Conjunctival Disease

UMLS symptoms related to Conjunctival Disease:


visual disturbance; eye manifestations

MGI Mouse Phenotypes related to Conjunctival Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 CCL11 CCR6 CD4 CD8A HRH1 IL10
2 immune system MP:0005387 10.03 ALB CCL11 CCR6 CD4 CD8A CRP
3 digestive/alimentary MP:0005381 9.97 ALB CD4 IL10 IL13 IL4 IL5
4 integument MP:0010771 9.61 CD4 CD8A IL10 IL13 IL1B IL4
5 liver/biliary system MP:0005370 9.23 ALB HRH1 IL10 IL4 IL5 IL6

Drugs & Therapeutics for Conjunctival Disease

Drugs for Conjunctival Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 7)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hyaluronic acid Approved, Vet_approved 9004-61-9 53477741
2 Pharmaceutical Solutions
3 Viscosupplements
4 Adjuvants, Immunologic
5 Ophthalmic Solutions
6 Protective Agents
7 Immunologic Factors

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Autologous Serum 20% and Autologous Serum 50% for the Treatment of Severe Dry Eye Unknown status NCT03436576 Phase 3 Autologous Serum 20%;Autologous Serum 50%
2 The Use of Natural Latex Biomembrane in Ocular Surface Reconstruction and Pterygium Completed NCT01250353 Phase 2
3 Measuring the Recovery of the Conjunctival Tissue After 4 Days of Scleral Lens Wear Completed NCT04340518
4 Ocular Microvascular Changes in Patients With Sepsis Completed NCT04214743
5 Three-dimensional Analysis of EMMPRIN on Conjunctival Epithelial Cells Surface in Severe Dry Eye Syndrome (ALTESSE) Recruiting NCT03358979
6 Clinical Efficacy of Smile Exercise Versus 0.1% Hyaluronic Acid Sodium Eye Drops for Dry Eye Symptoms in Patients With Dry Eye Disease: a Randomized, Controlled, Non-inferiority Trial Enrolling by invitation NCT04421300 0.1% sodium hyaluronate eye drop
7 Cytokine Profile of Conjunctivitis, Performed Through Tears Analysis Among Patients Treated With Dupilumab Not yet recruiting NCT04066998

Search NIH Clinical Center for Conjunctival Disease

Cochrane evidence based reviews: conjunctival diseases

Genetic Tests for Conjunctival Disease

Anatomical Context for Conjunctival Disease

MalaCards organs/tissues related to Conjunctival Disease:

40
Eye, Bone, Skin, Heart, Lung, Liver, Kidney

Publications for Conjunctival Disease

Articles related to Conjunctival Disease:

(show top 50) (show all 180)
# Title Authors PMID Year
1
Corneal and conjunctival fibroblasts are major sources of eosinophil-recruiting chemokines. 61 54
19700933 2009
2
Silicone Scaffold Support Using a Bilayer Dermal Regeneration Matrix Template for Correction of Primary or Recurrent Eyelid Retraction. 61
32826828 2021
3
Clinical Observation of Allergic Conjunctival Diseases with Portable and Recordable Slit-Lamp Device. 61
33802736 2021
4
Plasma cell granuloma of the conjunctiva in a young female. 61
32116097 2021
5
Long-term outcomes of 0.1% tacrolimus eye drops in eyes with severe allergic conjunctival diseases. 61
33522964 2021
6
[QUANTIFICATION OF CONJUNCTIVAL HYPEREMIA IN RABBITS USING ANALYSIS SOFTWARE]. 61
33597343 2021
7
Atypical ocular Chelonoid herpesvirus manifestations in a captive Loggerhead turtle (Caretta caretta). 61
33058466 2021
8
Use of allergen immunotherapy for treatment of allergic conjunctivitis. 61
33044339 2020
9
Roles of Type 2 Immune Response-Initiating Cytokines and Detection of Type 2 Innate Lymphoid Cells in Mouse Models of Allergic Conjunctivitis. 61
33038152 2020
10
Conjunctival reconstruction via enrichment of human conjunctival epithelial stem cells by p75 through the NGF-p75-SALL2 signaling axis. 61
32602639 2020
11
Current research progress in allergic conjunctival diseases. 61
33008568 2020
12
Objective evaluation of allergic conjunctival disease (with a focus on the application of artificial intelligence technology). 61
32563623 2020
13
The burden of acute conjunctivitis attributable to ambient particulate matter pollution in Singapore and its exacerbation during South-East Asian haze episodes. 61
32562998 2020
14
Nanotechnology for the Treatment of Allergic Conjunctival Diseases. 61
33138064 2020
15
Ocular allergy test and biomarkers on the ocular surface: Clinical test for evaluating the ocular surface condition in allergic conjunctival diseases. 61
32563624 2020
16
Japanese guidelines for allergic conjunctival diseases 2020. 61
33211650 2020
17
The effects of soft cryotherapy on conjunctiva and cornea in isolated pig eyes and comparison with standard liquid nitrogen: A pilot ex vivo study. 61
32154991 2020
18
Immune - Goblet cell interaction in the conjunctiva. 61
31953222 2020
19
Potential Biomarkers for Allergic Conjunctival Diseases. 61
32097185 2020
20
Effect of Diquafosol on Hyperosmotic Stress-induced Tumor Necrosis Factor-α and Interleukin-6 Expression in Human Corneal Epithelial Cells. 61
32037744 2020
21
Management of vernal keratoconjunctivitis in children in Saudi Arabia. 61
32174733 2020
22
Pathophysiological Role and Drug Modulation of Calcium Transport in Ocular Surface Cells. 61
31237195 2020
23
Local allergic conjunctivitis: a phenotype of allergic conjunctivitis. 61
31093805 2019
24
Topical Tacrolimus for Chronic Allergic Conjunctival Disease with and without Atopic Dermatitis. 61
30947551 2019
25
Urea-De-Epithelialized Human Amniotic Membrane for Ocular Surface Reconstruction. 61
30868769 2019
26
Evaluation of Chemokine mRNA Expression to Assess Allergic Inflammation of the Ocular Surface in Chronic Allergic Conjunctival Diseases. 61
30829721 2019
27
Optimized Protocol for Regeneration of the Conjunctival Epithelium Using the Cell Suspension Technique. 61
29923861 2019
28
Hyperemia Analysis Software for Assessment of Conjunctival Hyperemia Severity. 61
30512976 2019
29
Staged ocular fornix reconstruction for glaucoma drainage device under neoconjunctiva at the time of Boston type 1 Keratoprosthesis implantation. 61
30742989 2019
30
The proteolytic effect of mast cell tryptase to eotaxin-1/CCL11·eotaxin-2/CCL24 and eotaxin-3/CCL26 produced by conjunctival fibroblasts. 61
30796548 2019
31
Randomized controlled trials in ophthalmology: a bibliometric study. 61
32318264 2019
32
Plasma rich in growth factors membrane as coadjuvant treatment in the surgery of ocular surface disorders. 61
29702971 2018
33
Diagnosis, treatment, and outcome of and risk factors for ophthalmic disease in leopard geckos (Eublepharis macularius) at a veterinary teaching hospital: 52 cases (1985-2013). 61
29346051 2018
34
[GUIDELINES FOR THE CLINICAL MANAGEMENT OF ALLERGIC CONJUNCTIVAL DISEASE THE POINT OF THE MANAGEMENT WITH USING CONVENTIONAL TOOL AND EYE DROPS]. 61
29553108 2018
35
Clinical Severity and Tear Biomarkers, Eosinophil Cationic Protein and CCL23, in Chronic Allergic Conjunctival Diseases. 61
27929738 2018
36
Histamine H1 and H4 receptor expression on the ocular surface of patients with chronic allergic conjunctival diseases. 61
28391980 2017
37
Medical Management of Blepharokeratoconjunctivitis in Children: A Delphi Consensus. 61
27977033 2017
38
Amniotic Membrane Transplantation for Corneal and Conjunctival Diseases: Classification of Application and Outcomes from Analysis of 95 cases. 61
30070444 2017
39
Japanese guidelines for allergic conjunctival diseases 2017. 61
28209324 2017
40
Clinical and allergological analysis of ocular manifestations of sick building syndrome. 61
28352150 2017
41
JACQLQ (Japanese allergic conjunctival diseases Quality of Life Questionnaire). 61
28331105 2017
42
A case of Granulomatosis with Polyangiitis presenting with significant ocular cicatricial scarring and symblepharon formation. 61
29503914 2016
43
Conjunctival cicatrizing disease presenting with lacrimal obstruction. 61
27559621 2016
44
Partial orbit irradiation achieves excellent outcomes for primary orbital lymphoma. 61
26935235 2016
45
Goblet cell density and distribution in cats with clinically and histologically normal conjunctiva. 61
26799820 2016
46
Rothmund-Thomson syndrome and ocular surface findings: case reports and review of the literature. 61
27463631 2016
47
A retrospective analysis of eye conditions among children attending St. John Eye Hospital, Hebron, Palestine. 61
27048163 2016
48
Pyoblepharitis Vegetans in Association With Pyodermatitis-Pyostomatitis Vegetans: Expanding the Spectrum of a Rare, Multisystem Disorder. 61
26519160 2016
49
[A Review 65 Diagnosis and Treatment of Allergic Conjunctival Diseases]. 61
26950973 2016
50
Aqueous Tear Deficiency Increases Conjunctival Interferon-γ (IFN-γ) Expression and Goblet Cell Loss. 61
26618646 2015

Variations for Conjunctival Disease

Expression for Conjunctival Disease

Search GEO for disease gene expression data for Conjunctival Disease.

Pathways for Conjunctival Disease

Pathways related to Conjunctival Disease according to GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.09 TNF RNASE3 NLRP3 IL6 IL5 IL4
2
Show member pathways
13.91 TNF IL6 IL5 IL4 IL1B IL13
3
Show member pathways
13.78 TNF IL6 IL5 IL4 IL1B IL13
4
Show member pathways
13.65 TNF IL6 IL5 IL4 IL1B IL13
5
Show member pathways
13.51 TNF IL6 IL5 IL4 IL1B IL13
6
Show member pathways
13.47 TNF IL6 IL5 IL4 IL1B IL13
7
Show member pathways
13.41 TNF IL6 IL5 IL4 IL1B IL13
8
Show member pathways
13.26 TNF NLRP3 IL6 IL1B IL10 IFNA2
9
Show member pathways
13 TNF IL6 IL1B IFNA2 CXCL8 CD4
10 12.92 IL6 IL5 IL4 IL13 IFNA2 CXCL8
11
Show member pathways
12.9 TNF NLRP3 IL6 IL1B IFNA2 CXCL8
12
Show member pathways
12.79 TNF NLRP3 IL6 IL1B CXCL8
13
Show member pathways
12.74 TNF IL6 IL5 IL4 IL1B IL10
14
Show member pathways
12.72 TNF IL6 IL5 IL4 IL1B IL13
15
Show member pathways
12.69 TNF IL4 IL10 ICOSLG CD4
16
Show member pathways
12.65 TNF IL6 IL1B IL10 CD4
17 12.63 TNF IL4 IL1B IL10 CD8A
18
Show member pathways
12.57 TNF NLRP3 IL6 IL1B IFNA2 CXCL8
19
Show member pathways
12.56 IL6 IL5 IL4 IL13 IL10 IFNA2
20
Show member pathways
12.49 TNF IL6 IL5 IL4 IL1B IL13
21
Show member pathways
12.48 TNF IL6 IL4 IL1B CRP ALB
22
Show member pathways
12.47 TNF IL6 IL10 CXCL8 CCR6 CCL11
23
Show member pathways
12.41 TNF IL6 IL5 IL4 IL1B IL13
24 12.38 TNF NLRP3 IL6 IL1B IFNA2 CXCL8
25 12.35 TNF IL6 IL1B IL10 IFNA2
26
Show member pathways
12.33 TNF NLRP3 IL6 IL1B IL10
27
Show member pathways
12.33 TNF IL6 IL4 IL1B CXCL8 CCL11
28
Show member pathways
12.32 TNF IL4 IL1B IL10
29 12.32 TNF IL6 IL1B IL13 IL10 CXCL8
30
Show member pathways
12.28 TNF IL6 IL1B CXCL8
31
Show member pathways
12.27 TNF NLRP3 IL1B IFNA2
32
Show member pathways
12.21 TNF RNASE3 IL6 IL5 IL4 IL1B
33 12.2 TNF NLRP3 IL6 IL1B IL10 CXCL8
34 12.16 TNF IL6 IL4 IL1B CXCL8
35 12.08 TNF IL6 IL1B IL10 CXCL8
36
Show member pathways
12.07 IL4 IL1B CD8A CD4
37 12.07 TNF IL6 IL5 IL4 IL10 IFNA2
38 12.06 TNF IL6 IL5 IL4 IL1B CD8A
39 12.03 TNF IL6 IL4 IL1B IL13 IL10
40 12.01 TNF IL6 IL1B CXCL8
41 11.98 TNF IL6 IL1B CXCL8
42
Show member pathways
11.97 IL6 IL4 IL1B CD4
43 11.96 IL6 IL5 IL4 IL13 CXCL8
44 11.93 TNF NLRP3 IL6 IL1B IL10 CXCL8
45
Show member pathways
11.92 TNF IL6 IL1B IL10 CD4
46
Show member pathways
11.89 TNF IL5 IL4 CXCL8
47 11.89 TNF IL6 IL1B IL10 IFNA2 CD8A
48
Show member pathways
11.8 TNF IL6 IL1B CXCL8
49 11.8 TNF IL6 IL5 IL4 IL10 ICOSLG
50 11.79 IL5 IL4 IL10 CCL11

GO Terms for Conjunctival Disease

Cellular components related to Conjunctival Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.77 TNF RNASE3 IL6 IL5 IL4 IL1B
2 external side of plasma membrane GO:0009897 9.63 TNF IL13 ICOSLG CD8A CD4 CCR6
3 extracellular region GO:0005576 9.5 TNF RNASE3 NLRP3 IL6 IL5 IL4

Biological processes related to Conjunctival Disease according to GeneCards Suite gene sharing:

(show all 48)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.18 NLRP3 IL6 IL5 IL4 IL1B IL10
2 positive regulation of transcription, DNA-templated GO:0045893 10.11 TNF IL6 IL5 IL4 IL1B IL10
3 positive regulation of gene expression GO:0010628 10.09 TNF IL6 IL4 IL1B IL13 CXCL8
4 defense response GO:0006952 9.97 TNF NLRP3 IFNA2 ICOSLG CXCL8
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.96 TNF NLRP3 IL6 IL1B
6 chemotaxis GO:0006935 9.96 RNASE3 CXCL8 CCR6 CCL11
7 negative regulation of inflammatory response GO:0050728 9.94 NLRP3 IL4 IL13 IL10
8 defense response to Gram-positive bacterium GO:0050830 9.91 TNF RNASE3 IL6 CRP
9 inflammatory response GO:0006954 9.9 TNF NLRP3 IL6 IL5 IL1B IL13
10 positive regulation of DNA-binding transcription factor activity GO:0051091 9.89 TNF IL6 IL5 IL1B IL10
11 regulation of insulin secretion GO:0050796 9.88 TNF IL6 IL1B
12 positive regulation of T cell proliferation GO:0042102 9.88 IL6 IL4 IL1B CD4
13 chemokine-mediated signaling pathway GO:0070098 9.87 CXCL8 CCR6 CCL11
14 response to glucocorticoid GO:0051384 9.87 TNF IL6 IL10
15 positive regulation of smooth muscle cell proliferation GO:0048661 9.86 TNF IL6 IL13
16 humoral immune response GO:0006959 9.86 TNF IL6 IFNA2 CCR6
17 positive regulation of interleukin-8 production GO:0032757 9.85 TNF IL6 IL1B
18 positive regulation of interleukin-1 beta production GO:0032731 9.85 TNF NLRP3 IL6
19 cellular response to lipopolysaccharide GO:0071222 9.85 TNF NLRP3 IL6 IL1B IL10 CXCL8
20 T cell activation GO:0042110 9.84 IL4 ICOSLG CD8A CD4
21 positive regulation of B cell proliferation GO:0030890 9.82 IL5 IL4 IL13
22 positive regulation of interleukin-10 production GO:0032733 9.82 IL6 IL4 IL13
23 negative regulation of endothelial cell apoptotic process GO:2000352 9.81 IL4 IL13 IL10
24 microglial cell activation GO:0001774 9.79 TNF IL4 IL13
25 positive regulation of glial cell proliferation GO:0060252 9.77 TNF IL6 IL1B
26 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.77 TNF IL1B IL10
27 positive regulation of JAK-STAT cascade GO:0046427 9.76 TNF IL6 IL5 IL10
28 positive regulation of neuroinflammatory response GO:0150078 9.75 TNF IL6 IL1B
29 negative regulation of neurogenesis GO:0050768 9.73 TNF IL6 IL1B CCL11
30 immune response GO:0006955 9.73 TNF IL6 IL5 IL4 IL1B IL13
31 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.72 TNF IL6 IL4 IL13 IFNA2
32 regulation of establishment of endothelial barrier GO:1903140 9.7 TNF IL1B
33 positive regulation of mast cell degranulation GO:0043306 9.7 IL4 IL13
34 negative regulation of lipid storage GO:0010888 9.7 TNF IL6 CRP
35 endothelial cell apoptotic process GO:0072577 9.69 TNF IL10
36 negative regulation of acute inflammatory response GO:0002674 9.69 NLRP3 IL4
37 positive regulation of T-helper 2 cell cytokine production GO:2000553 9.68 NLRP3 IL6
38 positive regulation of mononuclear cell migration GO:0071677 9.67 TNF IL4
39 negative regulation of cytokine production involved in immune response GO:0002719 9.67 TNF IL10
40 type 2 immune response GO:0042092 9.67 IL4 IL10
41 positive regulation of fever generation GO:0031622 9.66 TNF IL1B
42 sequestering of triglyceride GO:0030730 9.65 TNF IL1B
43 vascular endothelial growth factor production GO:0010573 9.65 TNF IL6 IL1B
44 negative regulation of complement-dependent cytotoxicity GO:1903660 9.63 IL4 IL13
45 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.62 TNF IL1B
46 regulation of isotype switching GO:0045191 9.62 IL4 IL10
47 positive regulation of immunoglobulin production GO:0002639 9.56 IL6 IL5 IL13 IL10
48 cytokine-mediated signaling pathway GO:0019221 9.36 TNF IL6 IL5 IL4 IL1B IL13

Molecular functions related to Conjunctival Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.46 IL6 IL5 IL4 IL10
2 cytokine activity GO:0005125 9.32 TNF IL6 IL5 IL4 IL1B IL13
3 cytokine receptor binding GO:0005126 9.13 IL4 IL13 IFNA2

Sources for Conjunctival Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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