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MCID: CNJ004
MIFTS: 19

Conjunctival Pigmentation

Categories: Skin diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Conjunctival Pigmentation

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MalaCards integrated aliases for Conjunctival Pigmentation:

Name: Conjunctival Pigmentation 12 15 17 71

Classifications:

MalaCards categories:
Anatomical: Skin diseases
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External Ids:

Disease Ontology 12 DOID:12304
ICD9CM 34 372.55
SNOMED-CT 67 267645009
ICD10 32 H11.13
UMLS 71 C0155163
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Summaries for Conjunctival Pigmentation

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MalaCards based summary : Conjunctival Pigmentation is related to malignant dermis tumor and malignant skin fibrous histiocytoma. An important gene associated with Conjunctival Pigmentation is IFNA2 (Interferon Alpha 2), and among its related pathways/superpathways is Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include eye.

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Related Diseases for Conjunctival Pigmentation

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Diseases related to Conjunctival Pigmentation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Related Disease Score Top Affiliating Genes
1 malignant dermis tumor 10.0 MLANA IFNA2
2 malignant skin fibrous histiocytoma 10.0 MLANA IFNA2
3 severe cutaneous adverse reaction 10.0
4 erythema multiforme 10.0
5 vernal conjunctivitis 10.0
6 conjunctivitis 10.0
7 acne 10.0
8 keratoconjunctivitis 10.0
9 vernal keratoconjunctivitis 10.0
10 erythema multiforme major 10.0
11 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 10.0
12 sarcomatoid transitional cell carcinoma 10.0 MLANA CD68
13 spinal cord melanoma 10.0 MLANA CD68
14 malignant conjunctival melanoma 10.0 MLANA IFNA2
15 conjunctival cancer 10.0 MLANA IFNA2
16 orbit rhabdomyosarcoma 10.0 MLANA IFNA2
17 skin sarcoma 10.0 MLANA CD68
18 balloon cell malignant melanoma 10.0 MLANA CD68
19 rhinosporidiosis 10.0 IFNA2 CD68
20 parasitic ichthyosporea infectious disease 10.0 IFNA2 CD68
21 malignant granular cell myoblastoma 10.0 MLANA CD68
22 intravascular fasciitis 10.0 MLANA CD68
23 conjunctival nevus 10.0 SOX10 MLANA
24 gallbladder melanoma 10.0 SOX10 MLANA
25 bladder sarcoma 10.0 MLANA CD68
26 malignant giant cell tumor of the tendon sheath 9.9 SOX10 CD68
27 malignant choroid melanoma 9.9 SOX10 MLANA
28 cutaneous fibrous histiocytoma 9.9 MLANA CD68
29 epithelioid malignant peripheral nerve sheath tumor 9.9 SOX10 MLANA
30 malignant peripheral nerve sheath tumor 9.9 SOX10 MLANA
31 granular cell tumor 9.9 MLANA CD68
32 nasal cavity adenocarcinoma 9.9 SOX10 MLANA
33 mesenchymal cell neoplasm 9.9 MLANA CD68
34 connective tissue benign neoplasm 9.9 MLANA CD68
35 dowling-degos disease 1 9.9
36 retinal detachment 9.9
37 sympathetic ophthalmia 9.9
38 pyoderma 9.9
39 pyoderma gangrenosum 9.9
40 rosacea 9.9
41 ocular hypertension 9.9
42 large congenital melanocytic nevus 9.9 SOX10 MLANA
43 melanoma in congenital melanocytic nevus 9.8 SOX10 MLANA
44 skin benign neoplasm 9.8 MLANA CD68
45 clear cell sarcoma 9.8 SOX10 MLANA
46 vascular cancer 9.8 MLANA IFNA2 CD68
47 neurofibroma 9.7 SOX10 MLANA
48 angiosarcoma 9.7 MLANA CD68
49 melanoma, cutaneous malignant 1 9.7 SOX10 MLANA IFNA2
50 sarcomatoid squamous cell skin carcinoma 9.7 SOX10 MLANA CD68

Graphical network of the top 20 diseases related to Conjunctival Pigmentation:



Diseases related to Conjunctival Pigmentation
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Symptoms & Phenotypes for Conjunctival Pigmentation

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Drugs & Therapeutics for Conjunctival Pigmentation

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Search Clinical Trials , NIH Clinical Center for Conjunctival Pigmentation

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Genetic Tests for Conjunctival Pigmentation

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Anatomical Context for Conjunctival Pigmentation

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MalaCards organs/tissues related to Conjunctival Pigmentation:

40
Eye
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Publications for Conjunctival Pigmentation

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Articles related to Conjunctival Pigmentation:

(show top 50) (show all 52)
# Title Authors PMID Year
1
Primary acquired melanosis (PAM) without atypia/WHO low-grade conjunctival melanocytic intraepithelial lesion over areas of oculodermal melanocytosis. 61
33093059 2020
2
Bilateral Tarsal Conjunctival Pigmentation After Eight Months of Minocycline Therapy. 61
32809295 2020
3
Tear and serum interleukin-8 and serum CX3CL1, CCL2 and CCL5 in sulfur mustard eye-exposed patients. 61
31669888 2019
4
Imatinib-Related Conjunctival Pigmentation. 61
29935661 2018
5
Conjunctival Pigmentation Following Minocycline Therapy. 61
25226094 2016
6
Mascara-Induced Conjunctival Pigmentation. 61
27832281 2016
7
Conjunctival Melanoma With Morphologic Diversity and Orbital Invasion. 61
26909584 2016
8
Reversible Conjunctival Pigmentation Associated With Prostaglandin Use. 61
25967530 2016
9
In Vitro and In Vivo Evaluation of Cidofovir as a Topical Ophthalmic Antiviral for Ocular Canine Herpesvirus-1 Infections in Dogs. 61
26418618 2015
10
Unilateral Conjunctival in situ Squamous Carcinoma with Bilateral Conjunctival Chlorpromazine-Induced Secondary Melanosis Masquerading as in situ and Invasive Melanoma. 61
27171521 2015
11
Argon laser photoablation for postburn conjunctival pigmentation. 61
25505917 2014
12
[Interferon alpha 2b for treatment of conjunctival melanoma: a case report]. 61
23319061 2013
13
Argon laser photoablation of superficial conjunctival nevus: results of a 3-year study. 61
23394912 2013
14
Excision with corneoscleral lamellar keratoplasty and amniotic membrane transplantation of a corneal displaced recurrent conjunctival melanoma. 61
23060726 2012
15
The clinical significance of perilimbal conjunctival pigmentation in vernal conjunctivitis. 61
22237184 2012
16
Conjunctival pigmentation after 23-gauge microincisional vitrectomy surgery. 61
21852803 2011
17
The role of perivascular melanophage infiltrates in the conjunctiva in sympathetic ophthalmia. 61
21595534 2011
18
Endogenous ochronosis: case report and a systematic review of the literature. 61
21342157 2011
19
Conjunctival pigmentation after 25-gauge chandelier illumination system. 61
20516144 2010
20
Congenital yellow nail syndrome: a case report and its relationship to nonimmune fetal hydrops. 61
20807364 2010
21
A case of sympathetic ophthalmia presenting with extraocular symptoms and conjunctival pigmentation after repeated 23-gauge vitrectomy. 61
20662657 2010
22
Do antiglaucomatous prostaglandins induce melanogenesis in human conjunctiva?: an impression cytology pilot study. 61
20075674 2010
23
Primary acquired melanosis with atypia treated with mitomycin C. 61
18438612 2009
24
Perilimbal conjunctival pigmentation in Chinese patients with vernal keratoconjunctivitis. 61
17464306 2008
25
[Malignant melanoma of the conjunctiva]. 61
18642211 2008
26
Scleral and conjunctival pigmentation following minocycline therapy. 61
17641711 2007
27
Conjunctival pigmentation in Stevens-Johnson syndrome. 61
17984506 2007
28
Conjunctival pigmentation in Stevens-Johnson syndrome. 61
18004022 2007
29
Primary acquired melanosis of the conjunctiva. 61
16651212 2006
30
Perilimbal bulbar conjunctival pigmentation in vernal conjunctivitis: prospective evaluation of a new clinical sign in an Indian population. 61
15097129 2004
31
Conjunctival pigmentation as an adverse effect of latanoprost. 61
15004586 2004
32
Topical mitomycin treatment for primary acquired melanosis of the conjunctiva. 61
12644763 2003
33
Perilimbal conjunctival pigmentation in vernal keratoconjunctivitis: a new sign. 61
11973399 2002
34
Potentially life-threatening primary acquired melanosis. 61
11137435 2000
35
Topical mitomycin C chemotherapy for conjunctival melanoma and PAM with atypia. 61
9713051 1998
36
Conjunctival amelanotic malignant melanoma arising in primary acquired melanosis sine pigmento. 61
9442798 1998
37
Use of mitomycin C in the treatment of conjunctival primary acquired melanosis with atypia. 61
8859090 1996
38
Primary acquired melanosis and melanoma of the conjunctiva. 61
9396194 1996
39
Pigmented conjunctival and scleral lesions. 61
8309267 1994
40
Multifocal amelanotic conjunctival melanoma and acquired melanosis sine pigmento. 61
1540561 1992
41
Mascara pigmentation of the bulbar conjunctiva associated with rigid gas permeable lens wear. 61
1741114 1992
42
Transscleral cyclophotocoagulation of human autopsy and monkey eyes. 61
1792029 1991
43
Conjunctival pigmentation following pars plana vitrectomy. 61
3602605 1987
44
[Corneo-conjunctival pigmentation caused by lamprene]. 61
3790805 1986
45
Peutz-Jeghers syndrome. 61
3869001 1985
46
Corneal and superficial conjunctival pigmentation in Eskimos, Mongols, and Caucasians. 61
4050368 1985
47
Conjunctival pigmentation associated with tetracycline medication. 61
7322469 1981
48
[Conjunctival pigmentation following administration of adrenaline]. 61
761250 1979
49
Eye-cosmetic-induced conjunctival pigmentation. 61
677637 1978
50
Corneal and conjunctival pigmentation among workers in hydroquinone. 61
18919413 1947
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Variations for Conjunctival Pigmentation

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Expression for Conjunctival Pigmentation

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Search GEO for disease gene expression data for Conjunctival Pigmentation.
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Pathways for Conjunctival Pigmentation

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Pathways related to Conjunctival Pigmentation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 64
10.69 IFNA2 CD68
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GO Terms for Conjunctival Pigmentation

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Sources for Conjunctival Pigmentation

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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