Conjunctival Squamous Cell Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Disease Ontology: ¹¹ A conjunctival cancer characterized by abnormal growth of dysplastic squamous epithelial cells on the surface of the eye that arises from the conjunctiva that has infiltrated beyond the confines of the epithelial basement membrane.

MalaCards based summary: Conjunctival Squamous Cell Carcinoma, also known as squamous cell carcinoma of conjunctiva, is related to keratitis, hereditary and conjunctival cancer. An important gene associated with Conjunctival Squamous Cell Carcinoma is ADAM3A (ADAM Metallopeptidase Domain 3A (Pseudogene)), and among its related pathways/superpathways are T-cell activation SARS-CoV-2 and Inhibition of Ribosome Biogenesis by p14(ARF). The drugs Mitomycin and Fibrin Tissue Adhesive have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and t cells.

Wikipedia: ⁷⁵ Conjunctival squamous cell carcinoma (conjunctival SCC) and corneal intraepithelial neoplasia comprise... more...

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Related Diseases for Conjunctival Squamous Cell Carcinoma

Diseases related to Conjunctival Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 263)

#	Related Disease	Score	Top Affiliating Genes
1	keratitis, hereditary	30.7	KRT3 KRT12 CD4
2	conjunctival cancer	30.6	TP53 KRT12 IFNA2 CDKN2A
3	corneal intraepithelial neoplasm	30.5	IFNA2 IFNA1
4	pseudopterygium	30.5	KRT3 KRT12
5	papilloma	30.5	TYMS TP53 CDKN2A
6	acquired immunodeficiency syndrome	30.4	TP53 IFNA2 IFNA1 CD4
7	basosquamous carcinoma	30.4	TP53 KRT15
8	cervix uteri carcinoma in situ	30.4	TP53 CDKN2A CD4
9	basaloid squamous cell carcinoma	30.4	TP53 CDKN2A
10	actinic keratosis	30.4	TP53 IFNA1 CDKN2A CD4
11	punctate epithelial keratoconjunctivitis	30.3	KRT3 IFNA2
12	recurrent corneal erosion	30.2	KRT3 KRT12
13	conjunctival disease	30.2	IFNA2 IFNA1 CD4
14	conjunctival intraepithelial neoplasm	30.1	S100A2 IFNA2
15	keratopathy	30.1	KRT3 KRT12
16	human papillomavirus infectious disease	30.1	TP53 CDKN2A CD4
17	epidermodysplasia verruciformis 1	30.0	TP53 CDKN2A CD4
18	basal cell carcinoma	29.9	TP53 S100A2 KRT15 CDKN2A
19	eye disease	29.2	TP53 KRT3 KRT12 IFNA1 CDKN2A CD4
20	squamous cell carcinoma	10.9
21	immune deficiency disease	10.5
22	mucolipidosis iv	10.4
23	keratosis	10.4
24	hypopyon	10.4
25	xeroderma pigmentosum, variant type	10.3
26	viral infectious disease	10.3
27	lymphomatoid granulomatosis	10.3	IFNA2 IFNA1
28	ige responsiveness, atopic	10.3
29	dermatitis, atopic	10.3
30	basal cell carcinoma 1	10.3
31	keratomalacia	10.3
32	dermatitis	10.3
33	49, xxxxy syndrome	10.3
34	atopic keratoconjunctivitis	10.3
35	cryoglobulinemia, familial mixed	10.3	IFNA2 IFNA1
36	human immunodeficiency virus type 1	10.3
37	focal epithelial hyperplasia	10.3	TP53 IFNA2
38	necrotizing sialometaplasia	10.2	TP53 KRT15
39	geniculate ganglionitis	10.2	IFNA2 CD4
40	eccrine sweat gland cancer	10.2	TP53 KRT15
41	sebaceous gland neoplasm	10.2	TP53 KRT15
42	b-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	10.2	TP53 CDKN2A
43	endometrial squamous cell carcinoma	10.2	TP53 CDKN2A
44	esophagus verrucous carcinoma	10.2	TP53 CDKN2A
45	verrucous carcinoma	10.2	TP53 CDKN2A
46	gastric antral vascular ectasia	10.2
47	mucoepidermoid carcinoma	10.2
48	papillon-lefevre syndrome	10.2
49	pinguecula	10.2
50	excessive tearing	10.2

Graphical network of the top 20 diseases related to Conjunctival Squamous Cell Carcinoma:

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Symptoms & Phenotypes for Conjunctival Squamous Cell Carcinoma

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Drugs & Therapeutics for Conjunctival Squamous Cell Carcinoma

Drugs for Conjunctival Squamous Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Mitomycin

Approved

50-07-7

5746

2

Fibrin Tissue Adhesive

3

Anti-Bacterial Agents

4

Antibiotics, Antitubercular

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Anterior Segment Optical Coherence Tomography (AS-OCT) Guided Treatment of Diffuse Conjunctival Squamous Cell Carcinoma (CSCC) With Excision, Amniotic Membrane Graft Using Fibrin Glue and Topical Mitomycin C (MMC)	Completed	NCT03515954
2	Feasibility Study of Ocular Surface Squamous Neoplasia (OSSN) Surgical Excision in People Living With HIV in Sub-Saharan Africa (SSA)	Not yet recruiting	NCT04704648

Search NIH Clinical Center for Conjunctival Squamous Cell Carcinoma

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Genetic Tests for Conjunctival Squamous Cell Carcinoma

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Anatomical Context for Conjunctival Squamous Cell Carcinoma

Organs/tissues related to Conjunctival Squamous Cell Carcinoma:

MalaCards : Eye, Skin, T Cells, Retina, Endothelial, Liver

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Publications for Conjunctival Squamous Cell Carcinoma

Articles related to Conjunctival Squamous Cell Carcinoma:

(show top 50) (show all 619)

#	Title	Authors	PMID	Year
1	Clinicopathological characteristics of ocular surface squamous neoplasia: a 10-year review form a referral tertiary centre in Nigeria. ⁶²	Suleiman DE...Ahmed SA	35802299	2022
2	Brachytherapy as a curative option for ocular surface squamous neoplasia. ⁶²	Rahal A...Westekemper H	36436169	2022
3	Anterior segment optical coherence tomography characteristics of conjunctival papilloma as compared to papilliform ocular surface squamous neoplasia. ⁶²	Sripawadkul W...Karp CL	36402855	2022
4	Novel ocular immunotherapy induces tumor regression in an equine model of ocular surface squamous neoplasia. ⁶²	Wotman KL...Dow S	36367558	2022
5	Pegylated Interferon Alpha 2a for the Treatment of Ocular Surface Squamous Neoplasia. ⁶²	Park J...Choi CY	36107845	2022
6	Metastatic conjunctival squamous cell carcinoma: a study of 5 patients. ⁶²	Vempuluru VS...Kaliki S	35524835	2022
7	HPV16 conjunctival squamous cell carcinoma. ⁶²	Chiodi S...Rutigliani M	36377068	2022
8	Ocular Surface Squamous Neoplasia Masquerading as Recalcitrant Epithelial Keratitis. ⁶²	Watane A...Karp CL	34907943	2022
9	Unresectable and chemoresistant conjunctival squamous cell carcinoma on xeroderma pigmentosum treated by salvage radiation therapy: A case report and a review of the literature. ⁶²	Maimouna M...Dirk VG	36188050	2022
10	Supportive treatment to chemotherapy with MMC, in patients with ocular surface squamous neoplasia or conjunctival melanocytic tumor. ⁶²	Sammarco MG...Blasi MA	36074189	2022
11	Molluscum Contagiosum Masquerading as Ocular Surface Squamous Neoplasia. ⁶²	Younus O...Cauchi P	35760591	2022
12	OVOL1 immunohistochemical expression is a useful tool to diagnose invasion in ocular surface squamous neoplasms. ⁶²	Teran S...Zoroquiain P	35787378	2022
13	Spontaneous regression of presumed ocular surface squamous neoplasia: A report of 8 cases. ⁶²	Vempuluru VS...Kaliki S	34747253	2022
14	Ocular surface squamous neoplasia with 360° limbal involvement: a study of 130 patients. ⁶²	Vempuluru VS...Kaliki S	35951148	2022
15	Topical Chemotherapy for Treating Ocular Surface Squamous Neoplasia with a Combination of Interferon α-2b and 5-Fluorouracil. ⁶²	Geng W...Zhang MC	35704159	2022
16	Topical pharmacotherapy for ocular surface squamous neoplasia: systematic review and meta-analysis. ⁶²	Kozma K...Szalai E	35987957	2022
17	Ocular surface squamous neoplasia in New Zealand: a ten-year review of incidence in the Waikato region. ⁶²	Hossain RR...McKelvie J	34262162	2022
18	Ocular Surface Squamous Neoplasia: A 12-Month Prospective Evaluation of Incidence in Waikato, New Zealand. ⁶²	Hossain RR...McKelvie J	35997381	2022
19	Midterm results of conjunctival reconstruction with buccal mucosa and amniotic membrane after resecting ocular surface squamous neoplasia of the fornix. ⁶²	Rahal A...Westekemper H	35940212	2022
20	Holding back the tears: is there a role for marsupialisation? ⁶²	Chiu SJ...Tan JH	36161857	2022
21	Conjunctival myxoma masquerading as conjunctival lymphoma: A case report. ⁶²	Alkharashi M...Otaif W	35872550	2022
22	The Use of Panitumumab-IRDye800CW in a Novel Murine Model for Conjunctival Squamous Cell Carcinoma. ⁶²	Youn GM...Wu AY	35895055	2022
23	Clinicopathological profile, management and clinical outcomes in recurrent cases of ocular surface squamous neoplasia at a tertiary care centre. ⁶²	Kumar SV...Sati A	35857192	2022
24	Occurrence of Occult Neoplasia in Pterygium Specimens Among Hispanic and Non-Hispanic Patients. ⁶²	Zhu C...Kheirkhah A	35180019	2022
25	Bulbar conjunctival rhinosporidiosis mimicking ocular surface squamous neoplasia. ⁶²	Mishra DK...Bothra N	35900515	2022
26	The clinical presentation and treatment of an invasive conjunctival squamous spindle cell carcinoma. ⁶²	Chen CY...Wang JJ	36248073	2022
27	Optical coherence tomography angiography in the evaluation of vascular patterns of ocular surface squamous neoplasia during topical medical treatment. ⁶²	Theotoka D...Karp CL	35358712	2022
28	Racial and socioeconomic disparities in ocular surface squamous neoplasia: a National Cancer Database analysis. ⁶²	Zhang KY...Silberstein P	33977826	2022
29	Ocular surface squamous neoplasia in India: a study of 438 patients. ⁶²	Kaliki S...Mishra DK	35094225	2022
30	Management of coexisting bilateral ocular surface disease in xeroderma pigmentosum - sequence and outcomes. ⁶²	Rajagopal R...Agarwal M	35535407	2022
31	Identification of Metastatic Conjunctival Squamous Cell Carcinoma through Neck Palpation. ⁶²	Nishath T...Stacey AW	35950032	2022
32	Association of high-risk human papillomavirus with ocular surface squamous neoplasia: a case-control study in Mexico. ⁶²	De La Parra-Colin P...Hidalgo-Bravo A	35438930	2022
33	Clinical and Optical Coherence Tomography Comparison Between Ocular Surface Squamous Neoplasia and Squamous Metaplasia. ⁶²	Stevens SM...Dubovy S	35439777	2022
34	Treatment challenges associated with a superiorly located bulbar conjunctival mass-case report and review of the literature. ⁶²	Helayel HB...AlMutlak M	35128156	2022
35	Conjunctival Lesions: A 5-Year Basic Demographic Data and Clinicopathological Review in a Tertiary Eye Care Hospital. ⁶²	Alkatan HM...Alshalan AM	34846715	2022
36	Amniotic Membrane Grafting for Ocular Surface Inflammation Following Topical Interferon Alpha 2b Therapy. ⁶²	Shah SG...Shah GY	35298286	2022
37	Ocular surface squamous neoplasia in Northern Thailand: a 16-year review. ⁶²	Tananuvat N...Mahanupap P	35279126	2022
38	Clinical Significance of Cyclin Expression Profiling in Ocular Surface Squamous Neoplasia. ⁶²	Chauhan S...Bajaj MS	34657082	2022
39	A case of sight threatening complications from topical 1% 5-fluorouracil in the treatment of ocular surface squamous neoplasia. ⁶²	Lin WV...Suh LH	35128150	2022
40	Masquerade syndrome in ocular surface squamous neoplasia. ⁶²	Oliveira Cechim RV...Freitas D	35417519	2022
41	Immunohistochemical and mutational status of telomerase reverse transcriptase in conjunctival squamous cell carcinoma. ⁶²	Jayaraj P...Pushker N	35225554	2022
42	Pterygium and Ocular Surface Squamous Neoplasia: Optical Biopsy Using a Novel Autofluorescence Multispectral Imaging Technique. ⁶²	Habibalahi A...Goldys EM	35326744	2022
43	The impact of the COVID-19 pandemic on the diagnosis and treatment of ocular cancer. ⁶²	Fontes Junior VC...Belfort Neto R	35417515	2022
44	Ocular Surface Squamous Neoplasia With Coexistent Microbial Keratitis: Incidence, Risk Factors, Clinical Features, Microbiological Profile, and Treatment Outcome. ⁶²	Kapoor AG...Kaliki S	34294636	2022
45	Histopathological Rate of Ocular Surface Squamous Neoplasia in Clinically Suspected Pterygium Specimens: 10-Year Results. ⁶²	Modabber M...Kim E	34690264	2022
46	Ocular surface squamous neoplasia with orbital tumour extension: risk factors and outcomes. ⁶²	Kaliki S...Mohamed A	35115716	2022
47	Visualizing Ocular Surface Squamous Neoplasia. ⁶²	Witsberger EM...Patel SV	35065728	2022
48	Spontaneous rupture of ocular surface squamous neoplasia-a case report. ⁶²	Son JH...Lim SH	35186700	2022
49	Pegylated interferon-alpha-2a for the treatment of ocular surface squamous neoplasia. ⁶²	Nuruddin M...Hoque F	35388258	2022
50	Functional impact of titin (TTN) mutations in ocular surface squamous neoplasia. ⁶²	Djulbegovic MB...Harbour JW	34838574	2022

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Genes for Conjunctival Squamous Cell Carcinoma

Genes related to Conjunctival Squamous Cell Carcinoma (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ADAM3A	ADAM Metallopeptidase Domain 3A (Pseudogene)	Pseudogene	17.48	GeneCards inferred via : Publications Summaries (show sections)
2	IFNA2	Interferon Alpha 2	Protein Coding	8.43	DISEASES inferred ¹⁴
3	KRT12	Keratin 12	Protein Coding	6.66	DISEASES inferred ¹⁴
4	IFNA1	Interferon Alpha 1	Protein Coding	5.72	DISEASES inferred ¹⁴
5	TP53	Tumor Protein P53	Protein Coding	5.6	DISEASES inferred ¹⁴
6	KRT15	Keratin 15	Protein Coding	5.28	DISEASES inferred ¹⁴
7	ABCB5	ATP Binding Cassette Subfamily B Member 5	Protein Coding	5.17	DISEASES inferred ¹⁴
8	CDKN2A	Cyclin Dependent Kinase Inhibitor 2A	Protein Coding	5.02	DISEASES inferred ¹⁴
9	CD4	CD4 Molecule	Protein Coding	4.87	DISEASES inferred ¹⁴
10	TYMS	Thymidylate Synthetase	Protein Coding	4.86	DISEASES inferred ¹⁴
11	KRT3	Keratin 3	Protein Coding	4.82	DISEASES inferred ¹⁴
12	S100A2	S100 Calcium Binding Protein A2	Protein Coding	4.61	DISEASES inferred ¹⁴
13	CRCT1	Cysteine Rich C-Terminal 1	Protein Coding	4.61	DISEASES inferred ¹⁴

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Variations for Conjunctival Squamous Cell Carcinoma

Cosmic variations for Conjunctival Squamous Cell Carcinoma:

⁸ (show top 50) (show all 318)

#	Cosmic Mut ID	Gene Symbol	COSMIC Disease Classification (Primary site, Site subtype, Primary histology, Histology subtype)	Mutation CDS	Mutation AA	GRCh38 Location	Conf
1	COSM144706553	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.589T>C	p.Y197H	17:7674257-7674257	14
2	COSM144020377	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.692G>T	p.C231F	17:7674238-7674238	14
3	COSM122323579	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.310T>C	p.Y104H	17:7674257-7674257	14
4	COSM142560375	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.736G>A	p.E246K	17:7673767-7673767	14
5	COSM121886355	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.8G>T	p.C3F	17:7675208-7675208	14
6	COSM111766278	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.725G>T	p.C242F	17:7674238-7674238	14
7	COSM142568532	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.287G>T	p.C96F	17:7675208-7675208	14
8	COSM93191077	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.725G>T	p.C242F	17:7674238-7674238	14
9	COSM106105114	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.706T>C	p.Y236H	17:7674257-7674257	14
10	COSM121876085	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.457G>A	p.E153K	17:7673767-7673767	14
11	COSM93239210	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.706T>C	p.Y236H	17:7674257-7674257	14
12	COSM144087163	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.376G>A	p.E126K	17:7673767-7673767	14
13	COSM106053265	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.853G>A	p.E285K	17:7673767-7673767	14
14	COSM122741996	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.8G>T	p.C3F	17:7675208-7675208	14
15	COSM143949949	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.248G>T	p.C83F	17:7674238-7674238	14
16	COSM122271649	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.457G>A	p.E153K	17:7673767-7673767	14
17	COSM122278514	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.329G>T	p.C110F	17:7674238-7674238	14
18	COSM112260228	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.725G>T	p.C242F	17:7674238-7674238	14
19	COSM112253698	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.853G>A	p.E285K	17:7673767-7673767	14
20	COSM145025120	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.608G>T	p.C203F	17:7674238-7674238	14
21	COSM145067318	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.589T>C	p.Y197H	17:7674257-7674257	14
22	COSM112261547	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.404G>T	p.C135F	17:7675208-7675208	14
23	COSM87908091	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.404G>T	p.C135F	17:7675208-7675208	14
24	COSM143951100	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.-74G>T	p.?	17:7675208-7675208	14
25	COSM145017758	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.736G>A	p.E246K	17:7673767-7673767	14
26	COSM144092148	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.248G>T	p.C83F	17:7674238-7674238	14
27	COSM144659280	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.608G>T	p.C203F	17:7674238-7674238	14
28	COSM105684805	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.706T>C	p.Y236H	17:7674257-7674257	14
29	COSM112308171	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.706T>C	p.Y236H	17:7674257-7674257	14
30	COSM145026448	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.287G>T	p.C96F	17:7675208-7675208	14
31	COSM121934113	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.310T>C	p.Y104H	17:7674257-7674257	14
32	COSM143370962	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.736G>A	p.E246K	17:7673767-7673767	14
33	COSM144093313	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.-74G>T	p.?	17:7675208-7675208	14
34	COSM144021843	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.371G>T	p.C124F	17:7675208-7675208	14
35	COSM93183725	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.853G>A	p.E285K	17:7673767-7673767	14
36	COSM105627860	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.725G>T	p.C242F	17:7674238-7674238	14
37	COSM87906616	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.725G>T	p.C242F	17:7674238-7674238	14
38	COSM121884866	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.329G>T	p.C110F	17:7674238-7674238	14
39	COSM111812818	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.706T>C	p.Y236H	17:7674257-7674257	14
40	COSM143943874	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.376G>A	p.E126K	17:7673767-7673767	14
41	COSM144315997	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.608G>T	p.C203F	17:7674238-7674238	14
42	COSM142615001	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.589T>C	p.Y197H	17:7674257-7674257	14
43	COSM143993833	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.229T>C	p.Y77H	17:7674257-7674257	14
44	COSM143204251	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.229T>C	p.Y77H	17:7674257-7674257	14
45	COSM144310279	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.736G>A	p.E246K	17:7673767-7673767	14
46	COSM144317156	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.287G>T	p.C96F	17:7675208-7675208	14
47	COSM122740814	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.329G>T	p.C110F	17:7674238-7674238	14
48	COSM143379946	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.287G>T	p.C96F	17:7675208-7675208	14
49	COSM142881780	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.706T>C	p.Y236H	17:7674257-7674257	14
50	COSM111767835	TP53	eye,conjunctiva,carcinoma,squamous cell carcinoma	c.404G>T	p.C135F	17:7675208-7675208	14

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Expression for Conjunctival Squamous Cell Carcinoma

Search GEO for disease gene expression data for Conjunctival Squamous Cell Carcinoma.

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Pathways for Conjunctival Squamous Cell Carcinoma

Pathways related to Conjunctival Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	T-cell activation SARS-CoV-2 ⁷⁴ Show member pathways T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection ⁷⁴	11.51	TP53 CDKN2A CD4
2	Inhibition of Ribosome Biogenesis by p14(ARF) ⁶⁴	10.6	TP53 CDKN2A
3	TP53 network ⁷⁴ Show member pathways Activation, translocation and oligomerization of BAX ⁶⁶	10.26	TP53 CDKN2A
4	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha ⁶¹	9.85	TP53 CDKN2A

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GO Terms for Conjunctival Squamous Cell Carcinoma

Biological processes related to Conjunctival Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	epithelial cell differentiation	GO:0030855	9.1	KRT3 KRT15 KRT12

Sources

Sources for Conjunctival Squamous Cell Carcinoma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: CNJ018 MIFTS: 40	Conjunctival Squamous Cell Carcinoma Categories: Cancer diseases, Neuronal diseases, Skin diseases	Data Licensing For inquiries, contact: [email protected]
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