MCID: CNN005
MIFTS: 66

Connective Tissue Disease

Categories: Bone diseases, Cancer diseases, Muscle diseases, Skin diseases

Aliases & Classifications for Connective Tissue Disease

MalaCards integrated aliases for Connective Tissue Disease:

Name: Connective Tissue Disease 12 15 17
Connective Tissue Diseases 54 43 71
Abnormality of Connective Tissue 29 6
Connective Tissue Disorder 12 6
Disorder of Connective Tissue 12
Connective Tissue Disorders 42

Classifications:



External Ids:

Disease Ontology 12 DOID:65
MeSH 43 D003240
NCIt 49 C26729
UMLS 71 C0009782

Summaries for Connective Tissue Disease

MedlinePlus : 42 Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue. Over 200 disorders that impact connective tissue. There are different types: Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta Autoimmune disorders, such as lupus and scleroderma Cancers, like some types of soft tissue sarcoma Each disorder has its own symptoms and needs different treatment. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

MalaCards based summary : Connective Tissue Disease, also known as connective tissue diseases, is related to mixed connective tissue disease and collagen disease, and has symptoms including back pain, sciatica and muscle cramp. An important gene associated with Connective Tissue Disease is FBN1 (Fibrillin 1), and among its related pathways/superpathways are ERK Signaling and PAK Pathway. The drugs Pirfenidone and Aminolevulinic acid have been mentioned in the context of this disorder. Affiliated tissues include lung, skin and bone, and related phenotypes are cardiovascular system and cellular

Disease Ontology : 12 A musculoskeletal system disease that affects tissues such as skin, tendons, and cartilage.

Wikipedia : 74 A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as... more...

Related Diseases for Connective Tissue Disease

Diseases related to Connective Tissue Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 1274, show less)
# Related Disease Score Top Affiliating Genes
1 mixed connective tissue disease 36.6 TNF RNPC3 IL6 IL10 HSPD1 HLA-DRB1
2 collagen disease 34.5 TNF SMAD3 PLOD1 IL6 IL10 FBN1
3 aortic aneurysm, familial thoracic 1 33.8 SMAD3 FBN2 FBN1 COL5A1 COL3A1 ACTA2
4 systemic lupus erythematosus 33.8 TNF RNPC3 IL6 IL10 HSPD1 HLA-DRB1
5 rheumatic fever 33.7 TNF IL6 IL10 HLA-DRB1 CD40LG
6 marfan syndrome 33.6 FBN2 FBN1 COL5A1 COL3A1 ACTA2
7 raynaud disease 33.6 EDNRA CENPB CD40LG
8 weill-marchesani syndrome 33.3 TNF FBN2 FBN1 ADAMTS13
9 scleroderma, familial progressive 33.2 FBN1 CENPB
10 systemic scleroderma 33.2 TNF SFTPD IL6 FBN1 CENPB CD40LG
11 juvenile rheumatoid arthritis 33.1 TNF IL6 IL10 HLA-DRB1
12 arterial tortuosity syndrome 33.1 SMAD3 FBN1 COL3A1 ACTA2
13 sjogren syndrome 33.0 IL10 CENPB CD40LG APOH
14 autoimmune disease 33.0 TNF IL6 IL10 HSPD1 HLA-DRB1 CENPB
15 lung disease 33.0 TNF SFTPD IL6 IL10 CD40LG
16 interstitial lung disease 33.0 TNF SFTPD IL6 IL10 CD40LG
17 polyarteritis nodosa 32.9 SMAD3 IL6 HLA-DRB1 APOH
18 pulmonary hypertension 32.9 TNF SMAD3 IL6 EDNRA BMPR2 ACTA2
19 temporal arteritis 32.8 TNF IL6 HLA-DRB1 CD40LG APOH
20 vasculitis 32.8 TNF IL6 HSPD1 CD40LG APOH
21 takayasu arteritis 32.8 TNF IL6 IL10 HLA-DRB1 CD40LG APOH
22 rheumatic disease 32.8 TNF SFTPD RNPC3 IL10 HLA-DRB1 CENPB
23 childhood type dermatomyositis 32.7 TNF IL6 CD40LG
24 kawasaki disease 32.7 TNF IL6 IL10 HSPD1 CD40LG
25 behcet syndrome 32.6 TNF IL6 IL10 HSPD1 HLA-DRB1 CD40LG
26 microscopic polyangiitis 32.6 TNF HLA-DRB1
27 lupus erythematosus 32.6 TNF IL10 HLA-DRB1 CD40LG APOH
28 vascular disease 32.6 TNF IL6 IL10 HSPD1 CD40LG BMPR2
29 churg-strauss syndrome 32.5 TNF IL10 CD40LG
30 pulmonary fibrosis, idiopathic 32.5 TNF SMAD3 SFTPD IL6 IL10 COL3A1
31 pneumonia 32.5 TNF SFTPD IL6 IL10 HSPD1 CD40LG
32 adult-onset still's disease 32.5 TNF IL6 HLA-DRB1
33 purpura 32.4 TNF IL6 IL10 CD40LG APOH ADAMTS13
34 reactive arthritis 32.4 TNF IL6 IL10 HSPD1
35 antiphospholipid syndrome 32.4 TNF CD40LG APOH ADAMTS13
36 thrombocytopenia 32.4 TNF IL6 IL10 CD40LG APOH ADAMTS13
37 rheumatoid arthritis 32.3 TNF IL6 IL10 HSPD1 HLA-DRB1 CD40LG
38 primary biliary cirrhosis 32.3 TNF IL6 IL10 HSPD1 HLA-DRB1 CENPB
39 calcinosis 32.3 TNF HLA-DRB1 FBN1 CENPB
40 myocarditis 32.2 TNF IL6 IL10 CD40LG
41 exanthem 32.1 TNF IL6 IL10 CD40LG
42 spondylitis 32.1 TNF IL6 IL10
43 meningitis 32.1 TNF IL6 IL10 CD40LG
44 thrombotic thrombocytopenic purpura 32.1 HLA-DRB1 CD40LG APOH ADAMTS13
45 autoimmune hepatitis 32.1 TNF IL10 HLA-DRB1 CD40LG
46 portal hypertension 32.1 TNF EDNRA CD40LG BMPR2 ADAMTS13
47 sarcoidosis 1 32.1 TNF SFTPD HLA-DRB1 CD40LG
48 pericarditis 32.1 TNF IL6 CD40LG
49 psoriatic arthritis 32.0 TNF IL6 IL10 HLA-DRB1 CD40LG
50 myelitis 32.0 TNF IL6 IL10 CD40LG APOH
51 thyroiditis 32.0 TNF IL6 IL10
52 ehlers-danlos syndrome 32.0 PLOD1 FBN1 COL5A1 COL3A1
53 telangiectasis 32.0 FBN1 CENPB BMPR2
54 pre-eclampsia 31.9 TNF IL6 IL10 CD40LG APOH
55 pneumocystosis 31.9 TNF SFTPD IL6 CD40LG
56 cutaneous lupus erythematosus 31.9 TNF IL6 IL10 CD40LG
57 bronchiolitis 31.9 TNF SFTPD IL6 IL10 CD40LG
58 aseptic meningitis 31.9 TNF IL10 CD40LG
59 spondyloarthropathy 1 31.9 TNF HSPD1 CD40LG
60 localized scleroderma 31.9 TNF SMAD3 IL6
61 limited scleroderma 31.9 RNPC3 HLA-DRB1 EDNRA CENPB BMPR2
62 transverse myelitis 31.9 TNF IL6 IL10 APOH
63 peripheral nervous system disease 31.8 TNF IL6 IL10 CD40LG
64 discoid lupus erythematosus 31.8 IL10 HLA-DRB1 APOH
65 dilated cardiomyopathy 31.8 TNF IL6 IL10 HSPD1 HLA-DRB1 EDNRA
66 osteoporosis 31.8 TNF SMAD3 PLOD1 IL6 IL10 CD40LG
67 aortic aneurysm 31.8 SMAD3 IL6 FBN2 FBN1 COL3A1 ACTA2
68 aneurysm 31.8 SMAD3 FBN2 FBN1 COL3A1 ACTA2
69 skin disease 31.8 TNF SFTPD IL6 IL10 CD40LG
70 brittle bone disorder 31.8 PLOD1 FBN1 COL5A1 COL3A1
71 leprosy 3 31.8 TNF IL6 IL10 HSPD1 HLA-DRB1 CD40LG
72 hashimoto thyroiditis 31.7 TNF IL6 IL10 HLA-DRB1
73 inguinal hernia 31.7 IL6 HLA-DRB1 FBN1 COL5A1
74 placenta disease 31.7 TNF IL6 COL3A1 APOH
75 orthostatic intolerance 31.7 SMAD3 PLOD1 FBN2 FBN1 COL5A1 COL3A1
76 uveitis 31.7 TNF IL6 IL10 HSPD1
77 syphilis 31.7 HLA-DRB1 CD40LG APOH
78 drug-induced lupus erythematosus 31.7 TNF IL6 IL10
79 respiratory failure 31.7 TNF SFTPD IL6 IL10
80 viral hepatitis 31.7 TNF IL6 IL10 HLA-DRB1 CD40LG
81 inflammatory bowel disease 31.7 TNF SMAD3 IL6 IL10 HSPD1 HLA-DRB1
82 disseminated intravascular coagulation 31.7 TNF IL6 IL10 ADAMTS13
83 celiac disease 1 31.7 TNF IL6 IL10 HLA-DRB1 CD40LG
84 multiple sclerosis 31.6 TNF IL6 IL10 HSPD1 HLA-DRB1 CD40LG
85 chickenpox 31.6 TNF IL6 IL10 CD40LG
86 herpes zoster 31.6 TNF IL10 HLA-DRB1 CD40LG
87 loeys-dietz syndrome 31.6 SMAD3 FBN2 FBN1 COL5A1 COL3A1 ACTA2
88 bacterial infectious disease 31.6 TNF IL6 IL10 HSPD1 CD40LG
89 lyme disease 31.6 TNF IL6 HSPD1 HLA-DRB1 CD40LG
90 heart disease 31.6 TNF IL6 IL10 FBN1 EDNRA CD40LG
91 pemphigus 31.6 TNF IL10 HLA-DRB1 CD40LG
92 neuromyelitis optica 31.6 IL6 HLA-DRB1 CD40LG
93 aortic valve disease 1 31.6 SMAD3 PLOD1 FBN2 FBN1 COL5A1 COL3A1
94 spondyloarthropathy 31.5 TNF IL6 IL10
95 tenosynovitis 31.5 TNF IL6 CD40LG
96 migraine with or without aura 1 31.5 TNF IL6 EDNRA CD40LG APOH
97 aortic disease 31.5 SMAD3 IL6 FBN1 COL3A1 ACTA2
98 cryoglobulinemia 31.5 TNF IL6 IL10 HLA-DRB1 CD40LG APOH
99 diarrhea 31.5 TNF IL6 IL10 CD40LG
100 fibromyalgia 31.5 TNF IL6 IL10
101 varicose veins 31.5 TNF IL6 FBN1 COL3A1
102 esophagitis 31.5 TNF IL6 IL10
103 sclerosing cholangitis 31.5 TNF IL6 IL10 HLA-DRB1 CD40LG
104 cholangitis 31.5 TNF IL6 IL10 HLA-DRB1 CD40LG
105 tetanus 31.5 TNF IL6 IL10 CD40LG
106 bacterial pneumonia 31.5 TNF SFTPD IL6 IL10 CD40LG
107 cerebrovascular disease 31.5 TNF IL6 CD40LG APOH ADAMTS13 ACTA2
108 measles 31.4 TNF IL6 HLA-DRB1 CD40LG
109 silicosis 31.4 TNF SFTPD IL10
110 central nervous system vasculitis 31.4 TNF IL6 HLA-DRB1 CD40LG
111 meningoencephalitis 31.4 TNF IL6 IL10 CD40LG
112 graft-versus-host disease 31.4 TNF IL6 IL10 HLA-DRB1
113 acute cystitis 31.4 TNF IL6 IL10 CD40LG
114 candidiasis 31.4 TNF IL6 IL10 CD40LG
115 bronchiolitis obliterans 31.4 TNF SFTPD IL6 IL10
116 thrombocytopenic purpura, autoimmune 31.4 HLA-DRB1 CD40LG ADAMTS13
117 bronchitis 31.3 TNF IL6 IL10 CD40LG
118 familial mediterranean fever 31.3 TNF IL6 IL10
119 toxic shock syndrome 31.3 TNF IL6 IL10 HSPD1 EDNRA CD40LG
120 iridocyclitis 31.3 TNF IL6 CD40LG
121 neuritis 31.3 TNF IL6 IL10
122 extrinsic allergic alveolitis 31.3 SFTPD IL6 IL10
123 erysipelas 31.3 TNF IL6 CD40LG
124 leishmaniasis 31.3 TNF IL6 IL10 HLA-DRB1
125 bone inflammation disease 31.3 TNF IL6 IL10 HLA-DRB1 CD40LG
126 listeriosis 31.3 TNF IL6 IL10
127 pharyngitis 31.3 TNF IL6 HLA-DRB1 CD40LG
128 lymphoid interstitial pneumonia 31.2 TNF IL6 CD40LG
129 lepromatous leprosy 31.2 TNF IL10 HSPD1
130 polyradiculoneuropathy 31.2 IL10 HLA-DRB1 CD40LG
131 rubella 31.2 TNF IL6 IL10 HLA-DRB1 CD40LG
132 coronary artery anomaly 31.2 TNF IL6 IL10 CD40LG
133 proteasome-associated autoinflammatory syndrome 1 31.2 TNF IL6 IL10
134 demyelinating disease 31.2 TNF IL6 IL10 HLA-DRB1 CD40LG
135 arteriosclerosis 31.2 IL6 IL10 HSPD1 FBN1 EDNRA
136 endocarditis 31.2 TNF IL6 IL10 HSPD1 APOH
137 hellp syndrome 31.2 IL6 IL10 CD40LG APOH ADAMTS13
138 chorioretinitis 31.2 TNF IL6 IL10 CD40LG
139 ulcerative colitis 31.2 TNF SMAD3 IL6 IL10 HLA-DRB1
140 colitis 31.2 TNF SMAD3 IL6 IL10 HLA-DRB1
141 acute disseminated encephalomyelitis 31.2 IL10 HSPD1 HLA-DRB1 CD40LG
142 optic neuritis 31.2 TNF IL10 HLA-DRB1
143 encephalitis 31.2 TNF IL6 IL10 CD40LG
144 hair disease 31.1 TNF IL6 IL10 CD40LG
145 heritable thoracic aortic disease 31.1 SMAD3 FBN1 COL3A1 ACTA2
146 otitis media 31.1 TNF IL6 IL10 CD40LG
147 stroke, ischemic 31.1 IL6 FBN1 EDNRA APOH ADAMTS13
148 acute transverse myelitis 31.1 IL6 IL10
149 retinal vein occlusion 31.1 TNF IL6 CD40LG APOH
150 pulmonary disease, chronic obstructive 31.1 TNF SFTPD IL6 IL10
151 alopecia areata 31.1 TNF IL6 IL10 HLA-DRB1
152 scleral disease 31.1 TNF IL6 CD40LG
153 aspergillosis 31.1 TNF SFTPD IL6 IL10
154 visceral leishmaniasis 31.1 TNF IL10 HLA-DRB1
155 macs syndrome 31.1 TNF IL10 HSPD1
156 acquired immunodeficiency syndrome 31.1 TNF IL6 IL10 CD40LG
157 aortitis 31.1 TNF IL6 CD40LG
158 iritis 31.1 TNF IL6 CD40LG
159 crohn's disease 31.1 TNF IL6 IL10 HLA-DRB1
160 conjunctivitis 31.1 TNF IL6 IL10
161 hypersensitivity reaction type iii disease 31.1 TNF IL6 CD40LG
162 histoplasmosis 31.1 TNF HLA-DRB1 CD40LG
163 spotted fever 31.0 TNF IL10 CD40LG
164 irritable bowel syndrome 31.0 TNF IL6 IL10
165 scoliosis 31.0 PLOD1 IL6 FBN2 FBN1 COL5A1
166 keratitis, hereditary 31.0 TNF IL6 IL10
167 plague 31.0 TNF IL6 IL10
168 lymphoma, non-hodgkin, familial 31.0 TNF IL6 IL10 HLA-DRB1 CD40LG
169 eye disease 31.0 TNF IL6 IL10 FBN1 CD40LG
170 severe cutaneous adverse reaction 30.9 TNF HLA-DRB1 CD40LG
171 arteriovenous malformation 30.9 TNF IL6 BMPR2
172 contact dermatitis 30.9 TNF IL6 IL10
173 ileus 30.9 TNF IL6 IL10
174 pneumoconiosis 30.9 TNF IL6 IL10
175 common variable immunodeficiency 30.9 TNF IL6 IL10 CD40LG
176 lichen planus 30.8 TNF IL6 IL10
177 ehlers-danlos syndrome, classic type, 2 30.8 COL5A1 COL3A1
178 osteomyelitis 30.8 TNF IL6 IL10
179 neuromuscular disease 30.8 TNF IL6 IL10 CD40LG
180 sickle cell anemia 30.8 TNF IL6 CD40LG
181 corneal disease 30.8 TNF IL6 IL10
182 chronic fatigue syndrome 30.7 TNF IL6 IL10
183 tricuspid valve prolapse 30.6 FBN1 COL3A1
184 undifferentiated connective tissue disease 12.8
185 pulmonary arterial hypertension associated with connective tissue disease 12.6
186 secondary interstitial lung disease in childhood and adulthood associated with a connective tissue disease 12.6
187 overlapping connective tissue disease 12.5
188 secondary interstitial lung disease specific to childhood associated with a connective tissue disease 12.5
189 obsolete: unclassified overlapping connective tissue disease 12.4
190 emilin-1-related connective tissue disease 12.4
191 obsolete: connective tissue disease with eye involvement 12.4
192 bone fragility with contractures, arterial rupture, and deafness 12.2
193 mccune-albright syndrome 12.1
194 marden-walker syndrome 11.9
195 pulmonary hypertension, primary, 1 11.5
196 fibrodysplasia ossificans progressiva 11.5
197 ehlers-danlos syndrome, dermatosparaxis type 11.4
198 occipital horn syndrome 11.4
199 osteogenesis imperfecta, type xii 11.4
200 pulmonary fibrosis 11.4
201 crest syndrome 11.4
202 enthesopathy 11.4
203 synovitis 11.4
204 fasciitis 11.3
205 scleritis 11.3
206 pseudoxanthoma elasticum 11.3
207 ehlers-danlos syndrome, hypermobility type 11.3
208 loeys-dietz syndrome 2 11.3
209 winchester syndrome 11.3
210 bone disease 11.3
211 mucinoses 11.3
212 mediastinitis 11.3
213 lipodermatosclerosis 11.3
214 systemic onset juvenile idiopathic arthritis 11.3
215 hajdu-cheney syndrome 11.3
216 coronary artery dissection, spontaneous 11.3
217 lateral meningocele syndrome 11.3
218 cutis laxa, autosomal recessive, type ia 11.3
219 brittle cornea syndrome 2 11.3
220 ehlers-danlos syndrome, spondylodysplastic type, 2 11.3
221 gastroparesis 11.3
222 malaria 11.3 TNF IL6 IL10 HSPD1 HLA-DRB1 EDNRA
223 polymyositis 11.2
224 hypertension, essential 11.2 TNF SMAD3 IL6 IL10 FBN1 EDNRA
225 ehlers-danlos syndrome, vascular type 11.2
226 ehlers-danlos syndrome, kyphoscoliotic type, 1 11.2
227 commensal bacterial infectious disease 11.2 TNF IL6 IL10 HSPD1 EDNRA CD40LG
228 blood platelet disease 11.2 TNF IL6 IL10 CD40LG APOH ADAMTS13
229 diabetes mellitus, insulin-dependent 11.2 TNF IL6 IL10 HSPD1 HLA-DRB1 CD40LG
230 idiopathic neutropenia 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
231 panuveitis 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
232 echinococcosis 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
233 autoimmune disease of endocrine system 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
234 leptospirosis 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
235 autoimmune disease of gastrointestinal tract 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
236 chlamydia pneumonia 11.2 TNF IL6 IL10 HSPD1 CD40LG
237 chlamydia 11.2 TNF IL6 IL10 HSPD1 CD40LG
238 dengue hemorrhagic fever 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
239 mumps 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
240 primary systemic mycosis 11.2 TNF IL6 IL10 HSPD1 CD40LG
241 mycoplasma pneumoniae pneumonia 11.2 TNF SFTPD IL6 IL10 CD40LG
242 lymph node disease 11.2 TNF IL6 IL10 HSPD1 CD40LG
243 testicular disease 11.2 TNF IL6 IL10 HSPD1 CD40LG
244 autoimmune disease of central nervous system 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
245 relapsing-remitting multiple sclerosis 11.2 TNF IL6 IL10 HLA-DRB1 CD40LG
246 primary bacterial infectious disease 11.2 TNF IL6 IL10 HSPD1 CD40LG
247 blood coagulation disease 11.1 TNF IL6 CD40LG APOH ADAMTS13
248 autoimmune disease of musculoskeletal system 11.1 TNF IL6 IL10 CD40LG APOH
249 cutis laxa, autosomal dominant 1 11.1
250 ehlers-danlos syndrome, periodontal type, 1 11.1
251 osteogenesis imperfecta, type ix 11.1
252 weill-marchesani syndrome 1 11.1
253 ehlers-danlos syndrome, classic-like 11.1
254 weill-marchesani syndrome 2 11.1
255 osteogenesis imperfecta, type vii 11.1
256 osteogenesis imperfecta, type viii 11.1
257 osteogenesis imperfecta, type v 11.1
258 osteogenesis imperfecta, type xi 11.1
259 osteogenesis imperfecta, type x 11.1
260 osteogenesis imperfecta, type vi 11.1
261 cutis laxa, autosomal dominant 2 11.1
262 weill-marchesani syndrome 3 11.1
263 osteogenesis imperfecta, type xiii 11.1
264 osteogenesis imperfecta, type xiv 11.1
265 osteogenesis imperfecta, type xv 11.1
266 kyphoscoliotic ehlers-danlos syndrome 11.1
267 fungal meningitis 11.1 TNF IL6 IL10 CD40LG
268 immune system disease 11.1 TNF IL6 IL10 CD40LG APOH
269 african tick-bite fever 11.1 TNF IL6 IL10 CD40LG
270 orchitis 11.1 TNF IL6 IL10 CD40LG
271 autoimmune gastritis 11.1 TNF IL6 IL10 HLA-DRB1
272 cystic echinococcosis 11.1 IL6 IL10 HLA-DRB1 CD40LG
273 intermediate uveitis 11.1 TNF IL6 IL10 HLA-DRB1
274 bronchopneumonia 11.1 TNF IL6 IL10 CD40LG
275 streptococcus pneumonia 11.1 TNF IL6 IL10 CD40LG
276 urethritis 11.1 TNF IL6 HSPD1 CD40LG
277 viral pneumonia 11.1 TNF SFTPD IL6 IL10
278 lacrimal apparatus disease 11.1 TNF IL6 IL10 CD40LG
279 herpangina 11.1 TNF IL6 IL10 CD40LG
280 tularemia 11.1 TNF IL6 HSPD1 CD40LG
281 autoimmune disease of blood 11.1 IL6 IL10 CD40LG ADAMTS13
282 splenic disease 11.1 TNF IL6 IL10 CD40LG
283 autoimmune pancreatitis 11.1 TNF IL10 HLA-DRB1 CD40LG
284 trachoma 11.1 TNF IL6 IL10 HSPD1
285 middle ear disease 11.1 TNF IL6 IL10 CD40LG
286 dengue shock syndrome 11.1 TNF IL6 HLA-DRB1 CD40LG
287 conjunctival disease 11.1 TNF IL6 IL10 CD40LG
288 coccidiosis 11.1 TNF IL6 IL10 CD40LG
289 dysentery 11.1 TNF IL6 IL10 CD40LG
290 viral encephalitis 11.1 TNF IL6 IL10 CD40LG
291 autoimmune disease of urogenital tract 11.1 TNF IL6 IL10 CD40LG
292 rectal disease 11.1 TNF IL6 IL10 CD40LG
293 paracoccidioidomycosis 11.1 TNF IL6 IL10 CD40LG
294 endocardium disease 11.1 TNF IL6 HSPD1 CD40LG
295 plasmodium vivax malaria 11.1 TNF IL6 IL10 CD40LG
296 hepatic vascular disease 11.1 TNF IL6 CD40LG BMPR2
297 rheumatic heart disease 11.1 TNF IL6 IL10 HLA-DRB1
298 q fever 11.1 TNF IL6 IL10 CD40LG
299 opportunistic mycosis 11.1 TNF IL6 IL10 CD40LG
300 neonatal jaundice 11.1 TNF IL6 IL10 ADAMTS13
301 cellulitis 11.1 TNF IL6 IL10 CD40LG
302 spinal cord disease 11.1 TNF IL6 IL10 CD40LG
303 nose disease 11.1 TNF IL6 IL10 CD40LG
304 extrinsic cardiomyopathy 11.1 TNF IL6 IL10 CD40LG
305 hypersensitivity reaction type iv disease 11.1 TNF IL6 IL10 CD40LG
306 brucellosis 11.1 TNF IL6 IL10 CD40LG
307 typhoid fever 11.1 TNF IL6 HLA-DRB1 CD40LG
308 pulmonary alveolar proteinosis 11.1 TNF SFTPD IL6 IL10
309 parasitic helminthiasis infectious disease 11.1 TNF IL6 IL10 CD40LG
310 severe acute respiratory syndrome 11.1 TNF IL6 IL10 CD40LG
311 duodenal ulcer 11.1 TNF IL6 IL10 HLA-DRB1
312 uveal disease 11.1 TNF IL6 IL10 CD40LG
313 atrophic gastritis 11.1 TNF IL6 IL10 HLA-DRB1
314 legionellosis 11.1 TNF IL6 HSPD1 CD40LG
315 alcoholic hepatitis 11.1 TNF IL6 IL10 ADAMTS13
316 lymphatic system disease 11.1 TNF IL6 IL10 CD40LG
317 plasmodium falciparum malaria 11.1 TNF IL6 IL10 CD40LG
318 parasitic protozoa infectious disease 11.1 TNF IL6 IL10 CD40LG
319 toxoplasmosis 11.1 TNF IL6 IL10 CD40LG
320 adult respiratory distress syndrome 11.1 TNF SFTPD IL6 IL10
321 bronchial disease 11.1 TNF IL6 IL10 CD40LG
322 pulmonary tuberculosis 11.1 TNF IL6 IL10 HLA-DRB1
323 stomatitis 11.1 TNF IL6 IL10 CD40LG
324 intermittent claudication 11.1 IL6 IL10 CD40LG APOH
325 periodontitis 11.1 TNF IL6 IL10 HSPD1
326 cerebral arterial disease 11.1 IL6 EDNRA COL3A1 ACTA2
327 upper respiratory tract disease 11.1 TNF IL6 IL10 CD40LG
328 retinal artery occlusion 11.1 IL6 IL10 APOH ACTA2
329 nontuberculous mycobacterial lung disease 11.1 TNF HLA-DRB1 FBN1
330 aortic aneurysm, familial thoracic 2 11.1 FBN2 FBN1 COL3A1 ACTA2
331 combined thymoma 11.1 TNF IL10 ADAMTS13
332 transient hypogammaglobulinemia 11.1 TNF IL10 CD40LG
333 post-transplant lymphoproliferative disease 11.1 TNF IL6 IL10
334 leukocyte disease 11.1 TNF IL6 IL10 CD40LG
335 eales disease 11.1 TNF IL6 IL10
336 lung abscess 11.1 TNF IL6 CD40LG
337 sporotrichosis 11.1 TNF IL10 CD40LG
338 scarlet fever 11.1 TNF EDNRA CD40LG
339 intracranial aneurysm 11.1 TNF FBN2 EDNRA COL3A1
340 choroiditis 11.1 TNF IL10 CD40LG
341 familial thoracic aortic aneurysm and dissection 11.1 SMAD3 FBN1 COL3A1 ACTA2
342 salpingitis 11.1 TNF HSPD1 CD40LG
343 laryngitis 11.0 TNF IL6 CD40LG
344 trichomoniasis 11.0 TNF IL6 CD40LG
345 chronic conjunctivitis 11.0 TNF IL6 IL10
346 hantavirus hemorrhagic fever with renal syndrome 11.0 TNF IL6 CD40LG
347 catastrophic antiphospholipid syndrome 11.0 CD40LG APOH ADAMTS13
348 polyradiculopathy 11.0 TNF IL6 CD40LG
349 chronic pulmonary heart disease 11.0 TNF EDNRA BMPR2
350 cytomegalovirus retinitis 11.0 TNF IL10 HLA-DRB1
351 autoimmune disease of eyes, ear, nose and throat 11.0 TNF IL6 IL10
352 sympathetic ophthalmia 11.0 TNF IL10 HLA-DRB1
353 multidrug-resistant tuberculosis 11.0 TNF IL10 EDNRA
354 microscopic colitis 11.0 TNF IL6 HLA-DRB1
355 cysticercosis 11.0 IL6 IL10 CD40LG
356 primary thrombocytopenia 11.0 IL10 CD40LG ADAMTS13
357 cecal disease 11.0 TNF IL6 CD40LG
358 autoimmune lymphoproliferative syndrome 11.0 TNF IL10 CD40LG ACTA2
359 impetigo 11.0 IL6 EDNRA CD40LG
360 fallopian tube disease 11.0 TNF IL6 CD40LG
361 pyelitis 11.0 TNF IL6 CD40LG
362 endometrial disease 11.0 TNF IL6 IL10
363 lichen disease 11.0 TNF IL6 CD40LG
364 vaginitis 11.0 TNF IL6 IL10
365 poliomyelitis 11.0 TNF IL10 CD40LG
366 ehrlichiosis 11.0 IL10 HSPD1 CD40LG
367 gingival disease 11.0 TNF IL6 IL10
368 hepatopulmonary syndrome 11.0 TNF EDNRA BMPR2
369 pericardium disease 11.0 TNF IL6 CD40LG
370 perinatal necrotizing enterocolitis 11.0 TNF IL6 IL10
371 vaginal disease 11.0 TNF IL6 IL10
372 guillain-barre syndrome 11.0 TNF HLA-DRB1 CD40LG
373 scrub typhus 11.0 TNF IL10 CD40LG
374 viral infectious disease 11.0 TNF IL6 IL10 CD40LG
375 viral exanthem 11.0 FBN2 CD40LG APOH
376 williams-beuren syndrome 11.0
377 dermatitis herpetiformis 11.0 TNF IL10 CD40LG
378 subacute sclerosing panencephalitis 11.0 TNF IL6 IL10
379 erythema infectiosum 11.0 FBN2 CD40LG APOH
380 allergic bronchopulmonary aspergillosis 11.0 SFTPD IL10 HLA-DRB1
381 sudden infant death syndrome 11.0 TNF IL6 IL10 HSPD1
382 anus disease 11.0 TNF IL6 IL10
383 loeys-dietz syndrome 3 11.0 SMAD3 FBN1 ACTA2
384 monoclonal gammopathy of uncertain significance 11.0 TNF IL6 CD40LG
385 bacterial sepsis 11.0 TNF IL6 IL10
386 complex regional pain syndrome 11.0 TNF IL6 IL10
387 paranasal sinus disease 11.0 TNF IL10 CD40LG
388 nasal cavity disease 11.0 TNF IL6 IL10
389 punctate inner choroidopathy 11.0 TNF IL10
390 common cold 11.0 TNF IL6 IL10
391 external pathological resorption 11.0 TNF IL6
392 aphthous stomatitis 11.0 TNF IL6 IL10
393 pulmonary artery disease 11.0 IL6 CD40LG APOH
394 combined t cell and b cell immunodeficiency 11.0 IL6 IL10 CD40LG
395 aggressive periodontitis 11.0 TNF IL6 IL10
396 ileitis 11.0 TNF IL6 IL10
397 respiratory allergy 11.0 TNF IL6 IL10
398 systemic lupus erythematosus 9 11.0
399 systemic lupus erythematosus 11 11.0
400 bethlem myopathy 2 11.0
401 vein disease 11.0 TNF IL6 CD40LG
402 loeys-dietz syndrome 1 11.0 SMAD3 FBN1 ACTA2
403 appendicitis 11.0 TNF IL6 IL10
404 melioidosis 11.0 TNF IL6 IL10
405 juvenile myasthenia gravis 11.0 IL10 HLA-DRB1
406 tropical endomyocardial fibrosis 11.0 TNF IL10
407 bacterial vaginosis 11.0 TNF IL6 IL10
408 scorpion envenomation 11.0 TNF IL6
409 hypotrichosis 1 11.0 TNF IL6 IL10
410 tonsillitis 11.0 TNF IL6 IL10
411 infective endocarditis 11.0 TNF IL6 APOH
412 ainhum 11.0
413 vertical talus, congenital 11.0
414 hyaline fibromatosis syndrome 11.0
415 ossification of the posterior longitudinal ligament of spine 11.0
416 funisitis 11.0
417 frozen shoulder 11.0
418 ochronosis 11.0
419 volkmann contracture 11.0
420 plantar fascial fibromatosis 11.0
421 interstitial keratitis 11.0
422 periostitis 11.0
423 mounier-kuhn syndrome 11.0
424 necrotizing autoimmune myopathy 11.0
425 periodontal ehlers-danlos syndrome 11.0
426 bone structure disease 11.0 IL6 FBN2 FBN1
427 prostatitis 11.0 TNF IL6 IL10
428 pyelonephritis 11.0 TNF IL6 IL10
429 ehlers-danlos syndrome, arthrochalasia type, 1 11.0
430 ehlers-danlos syndrome, spondylodysplastic type, 1 11.0
431 myhre syndrome 11.0
432 buschke-ollendorff syndrome 11.0
433 peyronie disease 11.0
434 ehlers-danlos syndrome, cardiac valvular type 11.0
435 geroderma osteodysplasticum 11.0
436 wrinkly skin syndrome 11.0
437 osteogenesis imperfecta, type xix 11.0
438 ehlers-danlos syndrome, musculocontractural type, 1 11.0
439 ehlers-danlos syndrome, spondylodysplastic type, 3 11.0
440 weill-marchesani syndrome 4 11.0
441 cutis laxa, autosomal recessive, type ib 11.0
442 ehlers-danlos syndrome, kyphoscoliotic type, 2 11.0
443 osteogenesis imperfecta, type xvi 11.0
444 osteogenesis imperfecta, type xvii 11.0
445 cutis laxa, autosomal dominant 3 11.0
446 ehlers-danlos syndrome, periodontal type, 2 11.0
447 ehlers-danlos syndrome, arthrochalasia type, 2 11.0
448 osteogenesis imperfecta, type xviii 11.0
449 ehlers-danlos syndrome, classic-like, 2 11.0
450 ehlers-danlos syndrome progeroid type 11.0
451 autosomal recessive cutis laxa type i 11.0
452 arthrochalasia ehlers-danlos syndrome 11.0
453 musculocontractural ehlers-danlos syndrome 11.0
454 filariasis 11.0 TNF IL6 IL10
455 multifocal choroiditis 11.0 TNF IL10
456 allergic contact dermatitis 11.0 TNF IL6 IL10
457 idiopathic anterior uveitis 11.0 TNF IL6
458 salmonellosis 10.9 TNF IL6 IL10
459 streptococcal toxic-shock syndrome 10.9 TNF IL6
460 spotted fever rickettsiosis 10.9 TNF IL10
461 chorioamnionitis 10.9 TNF IL6 IL10
462 bullous impetigo 10.9 IL6 EDNRA
463 avian influenza 10.9 TNF SFTPD IL6
464 bacterial meningitis 10.9 TNF IL6 IL10
465 beryllium disease 10.9 TNF HLA-DRB1
466 primary progressive multiple sclerosis 10.9 TNF IL10 HLA-DRB1
467 cutaneous leishmaniasis 10.9 TNF IL6 IL10
468 angioimmunoblastic lymphadenopathy with dysproteinemia 10.9 TNF IL6
469 gingivitis 10.9 TNF IL6 IL10
470 osteosclerotic myeloma 10.9 IL6 CD40LG
471 lens disease 10.9 TNF IL6 FBN1
472 alcoholic liver cirrhosis 10.9 TNF IL6 IL10
473 familial abdominal aortic aneurysm 10.9 FBN1 COL3A1
474 sudden sensorineural hearing loss 10.9 IL6 APOH
475 rheumatoid arthritis interstitial lung disease 10.9 TNF SFTPD
476 palladium allergic contact dermatitis 10.9 TNF IL10
477 raynaud phenomenon 10.9
478 autoimmune atherosclerosis 10.9 HSPD1 APOH
479 japanese spotted fever 10.9 HSPD1 CD40LG
480 dermatomyositis 10.9
481 chronic beryllium disease 10.9 TNF HLA-DRB1
482 null-cell leukemia 10.8 TNF IL6
483 inclusion conjunctivitis 10.8 HSPD1 CD40LG
484 intracranial berry aneurysm 10.8 TNF IL6 EDNRA
485 non-alcoholic steatohepatitis 10.8 TNF IL6
486 osteonecrosis 10.8
487 sleep apnea 10.8 TNF IL6 IL10
488 diaphragmatic hernia, congenital 10.8 FBN1 EDNRA BMPR2
489 granulomatosis with polyangiitis 10.7
490 autoimmune hepatitis type 1 10.7 IL10 HLA-DRB1
491 radiation proctitis 10.7 TNF EDNRA
492 relapsing polychondritis 10.7
493 hypermobility syndrome 10.7
494 posterior urethral valves 10.7 TNF IL6
495 myositis 10.7
496 idiopathic interstitial pneumonia 10.6
497 eye lymphoma 10.6 IL6 IL10
498 reflex sympathetic dystrophy 10.5
499 osteochondrosis 10.5
500 hypersensitivity vasculitis 10.5
501 myopathy 10.5
502 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.5
503 endocrine exophthalmos 10.5 IL6 CD40LG
504 neuropathy 10.4
505 inflammatory spondylopathy 10.4
506 glomerulonephritis 10.4
507 pediatric systemic lupus erythematosus 10.4
508 nonspecific interstitial pneumonia 10.4
509 hemopericardium 10.4
510 pericardial effusion 10.4
511 metal allergy 10.3 IL10 HLA-DRB1
512 systemic autoimmune disease 10.3
513 heart block, congenital 10.3
514 fibrosis of extraocular muscles, congenital, 1 10.3
515 collagenoma, familial cutaneous 10.3
516 nephrotic syndrome 10.3
517 neutropenia 10.3
518 arthropathy 10.3
519 hemolytic anemia 10.3
520 arthritis 10.3
521 dysphagia 10.3
522 hypothyroidism 10.2
523 lymphopenia 10.2
524 panniculitis 10.2
525 cardiac tamponade 10.2
526 keratoconjunctivitis sicca 10.2
527 alopecia 10.2
528 bone mineral density quantitative trait locus 8 10.2
529 bone mineral density quantitative trait locus 15 10.2
530 allergic hypersensitivity disease 10.2
531 diffuse scleroderma 10.2
532 sensory peripheral neuropathy 10.2
533 hypereosinophilic syndrome 10.2
534 47,xyy 10.2
535 membranous nephropathy 10.1
536 polyneuropathy 10.1
537 liver disease 10.1
538 amyloidosis 10.1
539 anca-associated vasculitis 10.1
540 calvarial doughnut lesions with bone fragility 10.1
541 hyperostosis cranialis interna 10.1
542 hyperostosis frontalis interna 10.1
543 melorheostosis, isolated 10.1
544 osseous heteroplasia, progressive 10.1
545 arthrogryposis, distal, type 10 10.1
546 craniodiaphyseal dysplasia 10.1
547 goodpasture syndrome 10.1
548 van buchem disease 10.1
549 muscular dystrophy, congenital, producing arthrogryposis 10.1
550 sclerosteosis 1 10.1
551 thrombotic thrombocytopenic purpura, congenital 10.1
552 bone mineral density quantitative trait locus 18 10.1
553 calvarial hyperostosis 10.1
554 aneurysmal bone cysts 10.1
555 sclerosteosis 2 10.1
556 sting-associated vasculopathy, infantile-onset 10.1
557 autoimmune disease, multisystem, infantile-onset, 1 10.1
558 sclerosteosis 10.1
559 fibrous dysplasia 10.1
560 de quervain disease 10.1
561 calcific tendinitis 10.1
562 lethal midline granuloma 10.1
563 myositis fibrosa 10.1
564 condensing osteitis of the clavicle 10.1
565 infective myositis 10.1
566 juvenile polymyositis 10.1
567 macrophagic myofasciitis 10.1
568 melorheostosis with osteopoikilosis 10.1
569 oncogenic osteomalacia 10.1
570 isolated sternocostoclavicular hyperostosis 10.1
571 idiopathic eosinophilic myositis 10.1
572 unclassified vasculitis 10.1
573 drug-induced vasculitis 10.1
574 parasitic myositis 10.1
575 bacterial myositis 10.1
576 fungal myositis 10.1
577 viral myositis 10.1
578 infectious, fungal or parasitic myopathy 10.1
579 myalgia-eosinophilia syndrome associated with tryptophan 10.1
580 juvenile overlap myositis 10.1
581 mixed sclerosing bone dystrophy with extra-skeletal manifestations 10.1
582 tafro syndrome 10.1
583 neonatal dermatomyositis 10.1
584 systemic polyarteritis nodosa 10.1
585 secondary polyarteritis nodosa 10.1
586 single-organ polyarteritis nodosa 10.1
587 primary polyarteritis nodosa 10.1
588 mazabraud syndrome 10.1
589 monostotic fibrous dysplasia 10.1
590 cytophagic histiocytic panniculitis 10.1
591 pancytopenia 10.1
592 acute kidney failure 10.1
593 proliferative glomerulonephritis 10.1
594 liver cirrhosis 10.1
595 kidney disease 10.1
596 caffey disease 10.1
597 felty syndrome 10.1
598 patella, chondromalacia of 10.1
599 scheuermann disease 10.1
600 tumoral calcinosis, hyperphosphatemic, familial, 1 10.1
601 chronic recurrent multifocal osteomyelitis 10.1
602 osteoporosis, juvenile 10.1
603 bruck syndrome 10.1
604 primary hypertrophic osteoarthropathy 10.1
605 nodular nonsuppurative panniculitis 10.1
606 pigmented villonodular synovitis 10.1
607 osteochondritis dissecans 10.1
608 pyomyositis 10.1
609 intermittent hydrarthrosis 10.1
610 solitary bone cyst 10.1
611 thrombophilia due to thrombin defect 10.1
612 myasthenia gravis 10.1
613 rickets 10.1
614 protein-losing enteropathy 10.1
615 gout 10.1
616 keratoconjunctivitis 10.1
617 pulmonary embolism 10.1
618 bronchiectasis 10.1
619 banti's syndrome 10.1
620 cytokine deficiency 10.1
621 atherosclerosis susceptibility 10.1
622 gastroesophageal reflux 10.1
623 carpal tunnel syndrome 10.1
624 trigeminal neuralgia 10.1
625 systemic lupus erythematosus 1 10.1
626 crescentic glomerulonephritis 10.1
627 pneumatosis cystoides intestinalis 10.1
628 eclampsia 10.1
629 lymphadenitis 10.1
630 polycystic kidney disease 10.0
631 anemia, autoimmune hemolytic 10.0
632 eosinophilic fasciitis 10.0
633 deficiency anemia 10.0
634 atrioventricular block 10.0
635 cardiac arrest 10.0
636 sialadenitis 10.0
637 retinal vasculitis 10.0
638 agammaglobulinemia 10.0
639 tricuspid valve insufficiency 10.0
640 pustulosis of palm and sole 10.0
641 immune-complex glomerulonephritis 10.0
642 psoriasis 10.0
643 splenomegaly 10.0
644 spondylarthropathy 10.0
645 headache 10.0
646 diffuse alveolar hemorrhage 10.0
647 acroosteolysis 10.0
648 progressive familial heart block, type ia 10.0
649 neurofibromatosis, type iv, of riccardi 10.0
650 hyperprolactinemia 10.0
651 aspiration pneumonia 10.0
652 immunoglobulin alpha deficiency 10.0
653 hypogonadotropic hypogonadism 10.0
654 xerophthalmia 10.0
655 pneumothorax 10.0
656 hepatitis b 10.0
657 acute pancreatitis 10.0
658 ischemia 10.0
659 hyperglycemia 10.0
660 rapidly progressive glomerulonephritis 10.0
661 mesangial proliferative glomerulonephritis 10.0
662 pancreatitis 10.0
663 pulmonary venoocclusive disease 10.0
664 congestive heart failure 10.0
665 paraplegia 10.0
666 hyperthyroidism 10.0
667 septic arthritis 10.0
668 peritonitis 10.0
669 osteoarthritis 10.0
670 allergic angiitis 10.0
671 hansen's disease 10.0
672 nodular regenerative hyperplasia 10.0
673 encephalopathy 10.0
674 subacute cutaneous lupus erythematosus 10.0
675 thrombotic microangiopathy 10.0
676 osteopoikilosis 10.0
677 mammary paget's disease 10.0
678 paget's disease of bone 10.0
679 cryoglobulinemia, familial mixed 9.9
680 autosomal dominant polycystic kidney disease 9.9
681 type ii mixed cryoglobulinemia 9.9
682 lichen sclerosus et atrophicus 9.9
683 retinal detachment 9.9
684 chondrodysplasia punctata syndrome 9.9
685 immune deficiency disease 9.9
686 pulmonary venoocclusive disease 1, autosomal dominant 9.9
687 budd-chiari syndrome 9.9
688 coronary heart disease 1 9.9
689 human immunodeficiency virus type 1 9.9
690 systemic lupus erythematosus 12 9.9
691 myelodysplastic syndrome 9.9
692 hydrops, lactic acidosis, and sideroblastic anemia 9.9
693 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.9
694 cryptogenic organizing pneumonia 9.9
695 thrombosis 9.9
696 hepatic veno-occlusive disease 9.9
697 castleman disease 9.9
698 pleurisy 9.9
699 malignant hypertension 9.9
700 esophageal varix 9.9
701 pulmonary edema 9.9
702 goiter 9.9
703 hepatic coma 9.9
704 facial paralysis 9.9
705 renal tubular acidosis 9.9
706 cystitis 9.9
707 mononeuritis multiplex 9.9
708 optic nerve disease 9.9
709 nocardiosis 9.9
710 central nervous system disease 9.9
711 intestinal pseudo-obstruction 9.9
712 thyroid gland disease 9.9
713 t-cell leukemia 9.9
714 nervous system disease 9.9
715 sickle cell disease 9.9
716 47, xxy 9.9
717 fibrosing mediastinitis 9.9
718 neuromyelitis optica spectrum disorder 9.9
719 pleuroparenchymal fibroelastosis 9.9
720 retroperitoneal fibrosis 9.9
721 rheumatoid vasculitis 9.9
722 back pain 9.9
723 neonatal lupus erythematosus 9.9
724 acute liver failure 9.9
725 mucopolysaccharidosis, type ii 9.9
726 hurler syndrome 9.9
727 aortic aneurysm, familial abdominal, 1 9.8
728 pneumothorax, primary spontaneous 9.8
729 shprintzen-goldberg craniosynostosis syndrome 9.8
730 brittle cornea syndrome 1 9.8
731 spondyloepimetaphyseal dysplasia with joint laxity, type 1, with or without fractures 9.8
732 spondyloepimetaphyseal dysplasia, matrilin-3 related 9.8
733 alacrima, achalasia, and mental retardation syndrome 9.8
734 helix syndrome 9.8
735 meningocele 9.8
736 chronic mucocutaneous candidiasis 9.8
737 cerebritis 9.8
738 intracranial hypotension 9.8
739 epidermolysis bullosa dystrophica 9.8
740 muscular dystrophy 9.8
741 distal renal tubular acidosis 9.8
742 frontometaphyseal dysplasia 9.8
743 hypotonia 9.8
744 amyotrophic lateral sclerosis 1 9.8
745 atrial standstill 1 9.8
746 contractural arachnodactyly, congenital 9.8
747 ehlers-danlos syndrome, classic type, 1 9.8
748 ige responsiveness, atopic 9.8
749 pemphigus vulgaris, familial 9.8
750 lymphoma, hodgkin, classic 9.8
751 ocular motor apraxia 9.8
752 osteogenesis imperfecta, type iii 9.8
753 thymoma, familial 9.8
754 ataxia and polyneuropathy, adult-onset 9.8
755 yemenite deaf-blind hypopigmentation syndrome 9.8
756 malignant atrophic papulosis 9.8
757 macular degeneration, age-related, 1 9.8
758 dermatitis, atopic 9.8
759 ventricular fibrillation, paroxysmal familial, 1 9.8
760 progressive familial heart block, type ib 9.8
761 systemic lupus erythematosus 2 9.8
762 systemic lupus erythematosus 3 9.8
763 nasopharyngeal carcinoma 9.8
764 kala-azar 1 9.8
765 systemic lupus erythematosus 4 9.8
766 aplastic anemia 9.8
767 hepatitis c virus 9.8
768 systemic lupus erythematosus 6 9.8
769 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 9.8
770 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.8
771 livedoid vasculitis 9.8
772 erythema multiforme 9.8
773 adult t-cell leukemia 9.8
774 limb ischemia 9.8
775 aphasia 9.8
776 lymphoma 9.8
777 x-linked chondrodysplasia punctata 1 9.8
778 lymphoproliferative syndrome 9.8
779 cryptococcal meningitis 9.8
780 isolated ectopia lentis 9.8
781 left bundle branch hemiblock 9.8
782 interstitial nephritis 9.8
783 chondrocalcinosis 9.8
784 palindromic rheumatism 9.8
785 gestational diabetes 9.8
786 mononeuropathy 9.8
787 graves' disease 9.8
788 hepatitis a 9.8
789 hemolytic-uremic syndrome 9.8
790 right bundle branch block 9.8
791 pure red-cell aplasia 9.8
792 hepatic encephalopathy 9.8
793 poems syndrome 9.8
794 reye syndrome 9.8
795 pleural disease 9.8
796 urticaria 9.8
797 angioedema 9.8
798 thrombocytopenia due to platelet alloimmunization 9.8
799 constipation 9.8
800 hepatitis 9.8
801 ankylosis 9.8
802 lateral sclerosis 9.8
803 gastroenteritis 9.8
804 protein s deficiency 9.8
805 thrombophilia 9.8
806 periarthritis 9.8
807 thymoma 9.8
808 thymic carcinoma 9.8
809 gastritis 9.8
810 calciphylaxis 9.8
811 chronic inflammatory demyelinating polyradiculoneuropathy 9.8
812 demyelinating polyneuropathy 9.8
813 aortic valve insufficiency 9.8
814 muscular atrophy 9.8
815 end stage renal failure 9.8
816 bullous pemphigoid 9.8
817 herpes simplex 9.8
818 myeloid leukemia 9.8
819 dyskinesia of esophagus 9.8
820 heritable pulmonary arterial hypertension 9.8
821 hypermobile ehlers-danlos syndrome 9.8
822 48,xyyy 9.8
823 acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22) 9.8
824 allergic encephalomyelitis 9.8
825 antisynthetase syndrome 9.8
826 cutaneous polyarteritis nodosa 9.8
827 erythrokeratoderma ''en cocardes'' 9.8
828 granulocytopenia 9.8
829 heparin-induced thrombocytopenia 9.8
830 human t-cell leukemia virus type 1 9.8
831 linear scleroderma 9.8
832 lymphangiectasis 9.8
833 pemphigus foliaceus 9.8
834 autonomic dysfunction 9.8
835 chronic pain 9.8
836 mucopolysaccharidoses 9.8
837 obsolete: rapidly progressive glomerulonephritis 9.8
838 combined pulmonary fibrosis-emphysema syndrome 9.8
839 bronchiolitis obliterans with obstructive pulmonary disease 9.8
840 avascular necrosis 9.8
841 secondary vasculitis 9.8
842 erythema multiforme major 9.8
843 pik3ca-related overgrowth syndrome 9.8
844 red cell aplasia 9.8
845 gingival overgrowth 9.7
846 overgrowth syndrome 9.7
847 familial adenomatous polyposis 1 9.7
848 odontochondrodysplasia 9.7
849 alpha-2-deficient collagen disease 9.7
850 cutis laxa, autosomal recessive, type iia 9.7
851 diastrophic dysplasia 9.7
852 hydrocephalus, tall stature, joint laxity, and kyphoscoliosis 9.7
853 lipoid proteinosis of urbach and wiethe 9.7
854 scheie syndrome 9.7
855 anxiety 9.7
856 cutis laxa, autosomal recessive, type iic 9.7
857 hydrocephalus 9.7
858 mucopolysaccharidosis iii 9.7
859 avoidant personality disorder 9.7
860 personality disorder 9.7
861 mesenchymal cell neoplasm 9.7
862 atp6v0a2-related cutis laxa 9.7
863 plod1-related kyphoscoliotic ehlers-danlos syndrome 9.7
864 skeletal dysplasias 9.7
865 cerebral aneurysms 9.7
866 dysautonomia 9.7
867 intestinal polyposis syndrome 9.7
868 achondroplasia 9.7
869 neurofibromatosis, type ii 9.7
870 arteries, anomalies of 9.7
871 cardiac conduction defect 9.7
872 chiari malformation type i 9.7
873 epicanthus 9.7
874 hpa i recognition polymorphism, beta-globin-related 9.7
875 spondyloepiphyseal dysplasia with congenital joint dislocations 9.7
876 attention deficit-hyperactivity disorder 9.7
877 hypertelorism 9.7
878 cardiospondylocarpofacial syndrome 9.7
879 arthrogryposis, distal, type 7 9.7
880 parkinson disease, late-onset 9.7
881 hypokalemic periodic paralysis, type 1 9.7
882 polycystic kidney disease 1 with or without polycystic liver disease 9.7
883 pelvic organ prolapse 9.7
884 pseudoachondroplasia 9.7
885 chromosome 2q35 duplication syndrome 9.7
886 down syndrome 9.7
887 von hippel-lindau syndrome 9.7
888 australia antigen 9.7
889 buerger disease 9.7
890 cohen syndrome 9.7
891 epidermolysis bullosa dystrophica, autosomal recessive 9.7
892 gapo syndrome 9.7
893 factor xii deficiency 9.7
894 homocystinuria due to cystathionine beta-synthase deficiency 9.7
895 3-methylglutaconic aciduria, type iii 9.7
896 bruck syndrome 1 9.7
897 interstitial pneumonitis, desquamative, familial 9.7
898 polycythemia vera 9.7
899 orofaciodigital syndrome viii 9.7
900 menkes disease 9.7
901 reticuloendotheliosis, x-linked 9.7
902 branchiootic syndrome 1 9.7
903 bruck syndrome 2 9.7
904 systemic lupus erythematosus 5 9.7
905 potocki-lupski syndrome 9.7
906 chromosome 6q11-q14 deletion syndrome 9.7
907 loeys-dietz syndrome 5 9.7
908 hypertrophic scars 9.7
909 peyronie's disease 9.7
910 arrhythmogenic right ventricular cardiomyopathy 9.7
911 lissencephaly 9.7
912 autosomal recessive disease 9.7
913 recessive dystrophic epidermolysis bullosa 9.7
914 hyper ige syndrome 9.7
915 parotid disease 9.7
916 alport syndrome 9.7
917 visual epilepsy 9.7
918 coronary thrombosis 9.7
919 synostosis 9.7
920 otosclerosis 9.7
921 hyperostosis 9.7
922 thrombocytosis 9.7
923 craniosynostosis 9.7
924 acromegaly 9.7
925 rhizomelic chondrodysplasia punctata 9.7
926 membranoproliferative glomerulonephritis 9.7
927 thoracic outlet syndrome 9.7
928 tracheal stenosis 9.7
929 gm1 gangliosidosis 9.7
930 necrobiosis lipoidica 9.7
931 turner syndrome 9.7
932 granuloma annulare 9.7
933 hypokalemia 9.7
934 dysgraphia 9.7
935 gingival hypertrophy 9.7
936 diverticulitis 9.7
937 polycythemia 9.7
938 learning disability 9.7
939 zellweger syndrome 9.7
940 peroxisomal disease 9.7
941 homocystinuria 9.7
942 carotid artery dissection 9.7
943 developmental coordination disorder 9.7
944 keloid disorder 9.7
945 ltbp4-related cutis laxa 9.7
946 chiari malformation 9.7
947 gangliosidosis 9.7
948 lambdoid synostosis 9.7
949 perniosis 9.7
950 spondyloepimetaphyseal dysplasia joint laxity 9.7
951 developmental dyspraxia 9.7
952 seizure disorder 9.7
953 periodic paralysis 9.7
954 spontaneous intracranial hypotension 9.7
955 argyria 9.7
956 b4galt7-related spondylodysplastic ehlers-danlos syndrome 9.7
957 classic pyoderma gangrenosum 9.7
958 achard syndrome 9.7
959 pfeiffer syndrome 9.7
960 alzheimer disease 9.7
961 annular erythema 9.7
962 b-cell growth factor 9.7
963 burkitt lymphoma 9.7
964 breast cancer 9.7
965 cardiac arrhythmia 9.7
966 creatine phosphokinase, elevated serum 9.7
967 dupuytren contracture 9.7
968 ectopia lentis 1, isolated, autosomal dominant 9.7
969 ehlers-danlos syndrome, autosomal dominant, type unspecified 9.7
970 facial spasm 9.7
971 fibromuscular dysplasia 9.7
972 hernia, hiatus 9.7
973 hypercholesterolemia, familial, 1 9.7
974 hyperimmunoglobulin g1 syndrome 9.7
975 hypertriglyceridemia, familial 9.7
976 inclusion body myositis 9.7
977 leukemia, chronic lymphocytic 9.7
978 melkersson-rosenthal syndrome 9.7
979 myelopathy, htlv-1-associated 9.7
980 neutrophil migration 9.7
981 ocular cicatricial pemphigoid 9.7
982 osteogenesis imperfecta, type i 9.7
983 osteogenesis imperfecta, type ii 9.7
984 osteogenesis imperfecta, type iv 9.7
985 papillomatosis, confluent and reticulated 9.7
986 pectus excavatum 9.7
987 pernicious anemia 9.7
988 pityriasis rubra pilaris 9.7
989 porphyria cutanea tarda 9.7
990 dowling-degos disease 1 9.7
991 schistosoma mansoni infection, susceptibility/ 9.7
992 small cell cancer of the lung 9.7
993 spinal arachnoiditis 9.7
994 thyroid cancer, nonmedullary, 1 9.7
995 trichomegaly 9.7
996 triiodothyronine receptor auxiliary protein 9.7
997 vasculitis, lymphocytic, nodular 9.7
998 vitiligo-associated multiple autoimmune disease susceptibility 6 9.7
999 acrocallosal syndrome 9.7
1000 chondrosarcoma 9.7
1001 cystic fibrosis 9.7
1002 endocardial fibroelastosis 9.7
1003 fibrosclerosis, multifocal 9.7
1004 renal glucosuria 9.7
1005 pulmonary venoocclusive disease 2, autosomal recessive 9.7
1006 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 9.7
1007 hypoascorbemia 9.7
1008 myeloma, multiple 9.7
1009 myosclerosis, autosomal recessive 9.7
1010 myxedema 9.7
1011 reticulum cell sarcoma 9.7
1012 graves disease 1 9.7
1013 werner syndrome 9.7
1014 systemic lupus erythematosus 15 9.7
1015 fabry disease 9.7
1016 nuclear ribonucleic acid 9.7
1017 premature ovarian failure 1 9.7
1018 aging 9.7
1019 kearns-sayre syndrome 9.7
1020 helicobacter pylori infection 9.7
1021 patent ductus venosus 9.7
1022 leukemia, acute myeloid 9.7
1023 acute insulin response 9.7
1024 astigmatism 9.7
1025 homocysteinemia 9.7
1026 aceruloplasminemia 9.7
1027 langerhans cell histiocytosis 9.7
1028 psoriasis 7 9.7
1029 phace association 9.7
1030 vitiligo-associated multiple autoimmune disease susceptibility 1 9.7
1031 lymphangioleiomyomatosis 9.7
1032 bone mineral density quantitative trait locus 3 9.7
1033 allergic rhinitis 9.7
1034 neutrophilic dermatosis, acute febrile 9.7
1035 systemic lupus erythematosus 8 9.7
1036 esophagitis, eosinophilic, 1 9.7
1037 diabetes mellitus, ketosis-prone 9.7
1038 inflammatory bowel disease 13 9.7
1039 systemic lupus erythematosus 10 9.7
1040 systemic lupus erythematosus 13 9.7
1041 pulmonary hypertension, chronic thromboembolic, without deep vein thrombosis 9.7
1042 systemic lupus erythematosus 14 9.7
1043 fatty liver disease, nonalcoholic 1 9.7
1044 reynolds syndrome 9.7
1045 cholangitis, primary sclerosing 9.7
1046 nail disorder, nonsyndromic congenital, 10 9.7
1047 muscle hypertrophy 9.7
1048 systemic lupus erythematosus 16 9.7
1049 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.7
1050 chorea, childhood-onset, with psychomotor retardation 9.7
1051 mucopolysaccharidosis-plus syndrome 9.7
1052 hyperlipoproteinemia, type iii 9.7
1053 alkuraya-kucinskas syndrome 9.7
1054 chronic ulcer of skin 9.7
1055 peripheral vascular disease 9.7
1056 angina pectoris 9.7
1057 autoimmune vasculitis 9.7
1058 pemphigus gestationis 9.7
1059 hemophagocytic lymphohistiocytosis 9.7
1060 secretory diarrhea 9.7
1061 lambert-eaton myasthenic syndrome 9.7
1062 brachydactyly 9.7
1063 distal arthrogryposis 9.7
1064 diffuse large b-cell lymphoma 9.7
1065 metabolic acidosis 9.7
1066 first-degree atrioventricular block 9.7
1067 second-degree atrioventricular block 9.7
1068 renal fibrosis 9.7
1069 pain agnosia 9.7
1070 ischemic colitis 9.7
1071 cogan syndrome 9.7
1072 persistent generalized lymphadenopathy 9.7
1073 dental abscess 9.7
1074 glucocorticoid-induced osteoporosis 9.7
1075 drug allergy 9.7
1076 purpura fulminans 9.7
1077 erythema elevatum diutinum 9.7
1078 bone resorption disease 9.7
1079 stickler syndrome 9.7
1080 chronic myelomonocytic leukemia 9.7
1081 igg4-related disease 9.7
1082 mucolipidosis 9.7
1083 sensorineural hearing loss 9.7
1084 keratoconus 9.7
1085 venous insufficiency 9.7
1086 parotitis 9.7
1087 anthracosis 9.7
1088 lymphocytic leukemia 9.7
1089 osteomalacia 9.7
1090 mastitis 9.7
1091 hypospadias 9.7
1092 henoch-schoenlein purpura 9.7
1093 diphtheria 9.7
1094 mitral valve insufficiency 9.7
1095 autonomic neuropathy 9.7
1096 fissured tongue 9.7
1097 cauda equina syndrome 9.7
1098 infant gynecomastia 9.7
1099 portal vein thrombosis 9.7
1100 multicentric reticulohistiocytosis 9.7
1101 myopia 9.7
1102 hemosiderosis 9.7
1103 arachnoiditis 9.7
1104 leukemia 9.7
1105 secondary hyperparathyroidism 9.7
1106 von willebrand's disease 9.7
1107 acute leukemia 9.7
1108 gynecomastia 9.7
1109 hereditary hemorrhagic telangiectasia 9.7
1110 capillary disease 9.7
1111 choreatic disease 9.7
1112 mikulicz disease 9.7
1113 focal segmental glomerulosclerosis 9.7
1114 porphyria 9.7
1115 pulmonary sarcoidosis 9.7
1116 tuberous sclerosis 9.7
1117 hyperparathyroidism 9.7
1118 anterior scleritis 9.7
1119 facial neuralgia 9.7
1120 interstitial cystitis 9.7
1121 schistosomiasis 9.7
1122 peptic esophagitis 9.7
1123 algoneurodystrophy 9.7
1124 pyuria 9.7
1125 gonadal dysgenesis 9.7
1126 pemphigoid gestationis 9.7
1127 neuronal ceroid lipofuscinosis 9.7
1128 papilledema 9.7
1129 acute chest syndrome 9.7
1130 keratosis 9.7
1131 ichthyosis 9.7
1132 cheilitis 9.7
1133 factitious disorder 9.7
1134 hepatitis c 9.7
1135 hypogonadism 9.7
1136 telogen effluvium 9.7
1137 intestinal perforation 9.7
1138 iron metabolism disease 9.7
1139 central retinal vein occlusion 9.7
1140 gastric antral vascular ectasia 9.7
1141 dermatitis 9.7
1142 epidermolysis bullosa 9.7
1143 skin atrophy 9.7
1144 acute interstitial pneumonia 9.7
1145 hyperthyroxinemia 9.7
1146 euthyroid sick syndrome 9.7
1147 aleutian mink disease 9.7
1148 iga glomerulonephritis 9.7
1149 food allergy 9.7
1150 scleredema adultorum 9.7
1151 cutis laxa 9.7
1152 lipid metabolism disorder 9.7
1153 lipomatosis 9.7
1154 tropical spastic paraparesis 9.7
1155 lysosomal storage disease 9.7
1156 mood disorder 9.7
1157 histiocytosis 9.7
1158 granulomatous myositis 9.7
1159 skin carcinoma 9.7
1160 sagittal sinus thrombosis 9.7
1161 plexopathy 9.7
1162 brachial plexus neuritis 9.7
1163 plasmacytoma 9.7
1164 protein c deficiency 9.7
1165 thrombophlebitis 9.7
1166 acute myocarditis 9.7
1167 thyroid gland papillary carcinoma 9.7
1168 restrictive cardiomyopathy 9.7
1169 eosinophilic gastritis 9.7
1170 eosinophilic gastroenteritis 9.7
1171 intracranial thrombosis 9.7
1172 pyoderma 9.7
1173 granulomatous dermatitis 9.7
1174 macular retinal edema 9.7
1175 rhinitis 9.7
1176 large cell carcinoma 9.7
1177 type c thymoma 9.7
1178 uremia 9.7
1179 brain edema 9.7
1180 ureteral obstruction 9.7
1181 infertility 9.7
1182 aortic valve prolapse 9.7
1183 human immunodeficiency virus infectious disease 9.7
1184 intestinal disease 9.7
1185 t-cell adult acute lymphocytic leukemia 9.7
1186 subendocardial myocardial infarction 9.7
1187 eosinophilic pneumonia 9.7
1188 esophageal disease 9.7
1189 complement deficiency 9.7
1190 hypersplenism 9.7
1191 inherited metabolic disorder 9.7
1192 spinal stenosis 9.7
1193 lung lymphoma 9.7
1194 compartment syndrome 9.7
1195 b-cell lymphoma 9.7
1196 hypogonadotropism 9.7
1197 peptic ulcer disease 9.7
1198 chronic kidney disease 9.7
1199 carotid artery occlusion 9.7
1200 cocaine abuse 9.7
1201 paralytic ileus 9.7
1202 influenza 9.7
1203 acute cor pulmonale 9.7
1204 reticulosarcoma 9.7
1205 pyoderma gangrenosum 9.7
1206 eating disorder 9.7
1207 decubitus ulcer 9.7
1208 intermediate coronary syndrome 9.7
1209 erythromelalgia 9.7
1210 diabetes mellitus 9.7
1211 orbital plasma cell granuloma 9.7
1212 exophthalmos 9.7
1213 diabetes insipidus 9.7
1214 fatty liver disease 9.7
1215 dacryoadenitis 9.7
1216 necrotizing fasciitis 9.7
1217 diastolic heart failure 9.7
1218 hemophilia 9.7
1219 classic ehlers-danlos syndrome 9.7
1220 autoimmune encephalitis 9.7
1221 autoimmune enteropathy 9.7
1222 chromosomal triplication 9.7
1223 chronic intestinal pseudoobstruction 9.7
1224 chronic thromboembolic pulmonary hypertension 9.7
1225 congenital contractures 9.7
1226 coronary artery aneurysm 9.7
1227 cutaneous sclerosis 9.7
1228 diffuse cutaneous systemic sclerosis 9.7
1229 diffuse mesangial sclerosis 9.7
1230 dwarfism 9.7
1231 fibrillary glomerulonephritis 9.7
1232 homologous wasting disease 9.7
1233 htlv-1 associated myelopathy/tropical spastic paraparesis 9.7
1234 hypocomplementemic urticarial vasculitis 9.7
1235 kikuchi disease 9.7
1236 lathyrism 9.7
1237 mycobacterium chelonae 9.7
1238 myelodysplastic syndrome with excess blasts 9.7
1239 pityriasis lichenoides 9.7
1240 scleromyxedema 9.7
1241 spastic paraparesis 9.7
1242 thrombotic thrombocytopenic purpura, acquired 9.7
1243 vitreoretinal degeneration 9.7
1244 paraneoplastic syndromes 9.7
1245 syncope 9.7
1246 chronic cutaneous lupus erythematosus 9.7
1247 progeroid syndrome 9.7
1248 linear atrophoderma of moulin 9.7
1249 inflammatory myopathy with abundant macrophages 9.7
1250 isolated pulmonary capillaritis 9.7
1251 pulmonary hypertension owing to lung disease and/or hypoxia 9.7
1252 overlap myositis 9.7
1253 rare hereditary hemochromatosis 9.7
1254 cranial neuralgia 9.7
1255 primary anetoderma 9.7
1256 acute pandysautonomia 9.7
1257 acute sensory ataxic neuropathy 9.7
1258 pseudo-meigs syndrome 9.7
1259 primary eosinophilic gastrointestinal disease 9.7
1260 non-inflammatory vasculopathy 9.7
1261 congenital amyoplasia 9.7
1262 focal myositis 9.7
1263 mixed-type autoimmune hemolytic anemia 9.7
1264 lupus erythematosus panniculitis 9.7
1265 pauci-immune glomerulonephritis 9.7
1266 lymphedema 9.7
1267 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.7
1268 rare disease in surgical orthopedic 9.7
1269 cardiogenic shock 9.7
1270 severe immune-mediated enteropathy 9.7
1271 autoinflammatory syndrome 9.7
1272 refractory anemia 9.7
1273 rare pulmonary disease 9.7
1274 thyroid carcinoma 9.7

Graphical network of the top 20 diseases related to Connective Tissue Disease:



Diseases related to Connective Tissue Disease

Symptoms & Phenotypes for Connective Tissue Disease

UMLS symptoms related to Connective Tissue Disease:


back pain, sciatica, muscle cramp, joint symptom, musculoskeletal symptom

MGI Mouse Phenotypes related to Connective Tissue Disease:

45 (showing 14, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.35 ACTA2 BMPR2 CD40LG COL3A1 COL5A1 EDNRA
2 cellular MP:0005384 10.34 BMPR2 CD40LG CENPB COL3A1 EDNRA FBN1
3 growth/size/body region MP:0005378 10.32 BMPR2 CENPB COL3A1 COL5A1 EDNRA FBN1
4 mortality/aging MP:0010768 10.28 ADAMTS13 APOH BMPR2 CD40LG CENPB COL3A1
5 homeostasis/metabolism MP:0005376 10.25 ADAMTS13 APOH BMPR2 CD40LG COL3A1 EDNRA
6 hematopoietic system MP:0005397 10.23 ADAMTS13 BMPR2 CD40LG COL3A1 EDNRA FBN1
7 immune system MP:0005387 10.18 ADAMTS13 BMPR2 CD40LG COL3A1 EDNRA FBN1
8 embryo MP:0005380 10.16 BMPR2 COL5A1 EDNRA FBN1 HSPD1 IL10
9 endocrine/exocrine gland MP:0005379 10.15 CD40LG CENPB EDNRA FBN1 IL10 IL6
10 integument MP:0010771 10.15 BMPR2 CD40LG COL3A1 COL5A1 EDNRA FBN1
11 muscle MP:0005369 10 ACTA2 BMPR2 COL3A1 EDNRA FBN1 FBN2
12 respiratory system MP:0005388 9.81 BMPR2 COL3A1 EDNRA FBN1 FBN2 IL10
13 skeleton MP:0005390 9.65 BMPR2 CD40LG EDNRA FBN1 FBN2 IL10
14 vision/eye MP:0005391 9.32 ACTA2 ADAMTS13 BMPR2 COL5A1 EDNRA FBN2

Drugs & Therapeutics for Connective Tissue Disease

Drugs for Connective Tissue Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 327, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Pirfenidone Approved, Investigational Phase 4 53179-13-8 40632
2
Aminolevulinic acid Approved Phase 4 106-60-5 137
3
Linezolid Approved, Investigational Phase 4 165800-03-3 441401
4
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
5
Epoprostenol Approved Phase 4 61849-14-7, 35121-78-9 5280427 5282411
6
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
7
Nepafenac Approved, Investigational Phase 4 78281-72-8 151075
8
Etanercept Approved, Investigational Phase 4 185243-69-0
9
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
10
Silver sulfadiazine Approved, Vet_approved Phase 4 22199-08-2 441244
11
Nitric Oxide Approved Phase 4 10102-43-9 145068
12
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
13
AT-101 Approved, Investigational Phase 4 90141-22-3, 652-67-5 12597
14
Isosorbide Dinitrate Approved, Investigational Phase 4 87-33-2 6883
15
Bisoprolol Approved Phase 4 66722-44-9 2405
16
Ramipril Approved Phase 4 87333-19-5 5362129
17
leucovorin Approved Phase 4 58-05-9 6006 143
18
Adalimumab Approved Phase 4 331731-18-1 16219006
19
Budesonide Approved Phase 4 51333-22-3 63006 5281004
20
Sirolimus Approved, Investigational Phase 4 53123-88-9 5284616 6436030 46835353
21
Everolimus Approved Phase 4 159351-69-6 6442177 70789204
22
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
23
Angiotensin II Approved, Investigational Phase 4 68521-88-0, 4474-91-3, 11128-99-7 172198
24
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
25
Bosentan Approved, Investigational Phase 4 147536-97-8 104865
26
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244