ABS
MCID: CNS013
MIFTS: 34

Constricting Bands, Congenital (ABS)

Categories: Bone diseases, Fetal diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Constricting Bands, Congenital

MalaCards integrated aliases for Constricting Bands, Congenital:

Name: Constricting Bands, Congenital 56 71
Amniotic Band Sequence 56 58
Amniotic Band Syndrome 52 58
Streeter Anomaly 56 52
Congenital Constricting Bands 52
Congenital Ring Constrictions 58
Congenital Constricting Band 74
Amniotic Band Sequence; Abs 56
Constriction Rings Syndrome 58
Constriction Band Syndrome 58
Amniotic Bands Sequence 52
Familial Amniotic Bands 52
Streeter Dysplasia 58
Abs 56

Characteristics:

OMIM:

56
Inheritance:
isolated cases

Miscellaneous:
incidence 1/1,200-1/15,000 live births
distribution of involvement is variable and may include craniofacial, thoracic, abdominal, and extremity structures


HPO:

31
constricting bands, congenital:
Inheritance sporadic


Classifications:

Orphanet: 58  
Rare bone diseases
Developmental anomalies during embryogenesis


Summaries for Constricting Bands, Congenital

NIH Rare Diseases : 52 Amniotic band syndrome refers to a condition in which bands develop from the inner lining of the amnion . The amnion is the sac that surrounds the baby in the womb. As the baby develops in the womb, the bands may attach to and affect the development of different areas of the body. This may result in constriction of the affected area or even amputation. The signs and symptoms vary greatly depending on the area(s) of the body involved and may include: shortened or absent digits (fingers and/or toes) or limbs (arms and/or legs), an opening in the abdomen through which various abdominal organs can protrude (abdominal wall defects ), protrusion of a portion of the brain and its surrounding membranes through a skull defect (encephalocele ), and cleft lip and/or palate . In most instances, the cause of amniotic bands remains unknown. Researchers have suggested two main theories to explain the development: the extrinsic theory and the intrinsic theory. The extrinsic theory states that amniotic band syndrome occurs due to factors found outside of the developing baby (externally); the intrinsic theory states that amniotic band syndrome occurs due to factors found within the baby (internally). Treatment differs depending on the severity of the condition and the areas of the body affected and may include surgery, physical therapy , and occupational therapy.

MalaCards based summary : Constricting Bands, Congenital, also known as amniotic band sequence, is related to gm2-gangliosidosis, ab variant and thymoma type ab. Affiliated tissues include brain, skin and lung, and related phenotypes are scoliosis and cleft palate

Wikipedia : 74 Constriction ring syndrome (CRS) is a congenital disorder with unknown cause. Because of the unknown... more...

More information from OMIM: 217100

Related Diseases for Constricting Bands, Congenital

Diseases related to Constricting Bands, Congenital via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 718)
# Related Disease Score Top Affiliating Genes
1 gm2-gangliosidosis, ab variant 12.9
2 thymoma type ab 12.3
3 malignant type ab thymoma 12.2
4 gm2-gangliosidosis, b, b1, ab variant 12.2
5 antley-bixler syndrome 11.6
6 gangliosidosis 11.6
7 tay-sachs disease 11.5
8 antley-bixler syndrome with genital anomalies and disordered steroidogenesis 11.3
9 antley-bixler syndrome without genital anomalies or disordered steroidogenesis 11.3
10 hypoglossia-hypodactylia 11.3
11 fibular hemimelia 11.3
12 pseudoainhum 11.3
13 anemia, sideroblastic, 4 11.2
14 mucolipidosis iii alpha/beta 11.2
15 mycobacterium abscessus 11.2
16 mixed type thymoma 11.2
17 fraser jequier chen syndrome 11.2
18 acute bilirubin encephalopathy 11.2
19 intraocular pressure quantitative trait locus 10.7
20 open-angle glaucoma 10.6
21 syphilis 10.6
22 glaucoma, primary open angle 10.5
23 cataract 10.4
24 triiodothyronine receptor auxiliary protein 10.4
25 ovarian cancer 10.4
26 thymoma, familial 10.4
27 helix syndrome 10.4
28 thymoma 10.4
29 gm2 gangliosidosis 10.3
30 aneurysm 10.3
31 tetanus 10.3
32 facial cleft 10.3
33 systemic lupus erythematosus 10.3
34 transient pseudohypoaldosteronism 10.3
35 dowling-degos disease 1 10.2
36 rapidly involuting congenital hemangioma 10.2
37 leprosy 3 10.2
38 myasthenia gravis 10.2
39 lupus erythematosus 10.2
40 hansen's disease 10.2
41 allergic encephalomyelitis 10.2
42 thyroid carcinoma 10.1
43 cleft lip 10.1
44 cleft lip/palate 10.1
45 autoimmune disease 10.1
46 colorectal cancer 10.1
47 hair whorl 10.1
48 thrombocytopenia 10.1
49 severe combined immunodeficiency 10.1
50 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.1

Graphical network of the top 20 diseases related to Constricting Bands, Congenital:



Diseases related to Constricting Bands, Congenital

Symptoms & Phenotypes for Constricting Bands, Congenital

Human phenotypes related to Constricting Bands, Congenital:

31 (show all 15)
# Description HPO Frequency HPO Source Accession
1 scoliosis 31 HP:0002650
2 cleft palate 31 HP:0000175
3 talipes equinovarus 31 HP:0001762
4 cleft upper lip 31 HP:0000204
5 hand polydactyly 31 HP:0001161
6 encephalocele 31 HP:0002084
7 omphalocele 31 HP:0001539
8 facial cleft 31 HP:0002006
9 abnormal lung lobation 31 HP:0002101
10 gastroschisis 31 HP:0001543
11 syndactyly 31 HP:0001159
12 bladder exstrophy 31 HP:0002836
13 abnormality of the rib cage 31 HP:0001547
14 eyelid coloboma 31 HP:0000625
15 ectopia cordis 31 HP:0001683

Symptoms via clinical synopsis from OMIM:

56
Skeletal Spine:
scoliosis

Skeletal Feet:
talipes equinovarus
ring-like finger constrictions
syndactyly, distal
congenital amputation

Abdomen External Features:
omphalocele
gastroschisis
abdominoschisis

Genitourinary Bladder:
bladder exstrophy

Head And Neck Eyes:
eyelid coloboma
orbital clefts

Head And Neck Face:
facial clefts

Head And Neck Mouth:
cleft palate
cleft lip

Head And Neck Head:
encephalocele

Respiratory Lung:
abnormal lung lobation

Skeletal Hands:
polydactyly
ring-like finger constrictions
syndactyly, distal
congenital amputation

Cardiovascular Heart:
ectopia cordis

Chest External Features:
thoracoschisis

Clinical features from OMIM:

217100

Drugs & Therapeutics for Constricting Bands, Congenital

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Influence of 3D Printed Prostheses on Neural Activation Patterns of the Primary Motor Cortex in Children With Unilateral Congenital Upper-limb Reductions Not yet recruiting NCT04110730

Search NIH Clinical Center for Constricting Bands, Congenital

Genetic Tests for Constricting Bands, Congenital

Anatomical Context for Constricting Bands, Congenital

MalaCards organs/tissues related to Constricting Bands, Congenital:

40
Brain, Skin, Lung, Bone, T Cells, Kidney, Thyroid

Publications for Constricting Bands, Congenital

Articles related to Constricting Bands, Congenital:

(show top 50) (show all 325)
# Title Authors PMID Year
1
Typical facial clefting and constriction band anomalies: an unusual association in three unrelated patients. 61 56
12833410 2003
2
Amniotic band sequence: Streeter's hypothesis reexamined. 61 56
1488974 1992
3
The amniotic band syndrome in monozygotic twins. 61 56
6869458 1983
4
Phenotype and genotype in 17 patients with Goltz-Gorlin syndrome. 56
19586929 2009
5
Developmental anomalies with features of disorganization (Ds) and amniotic band sequence (ABS): A report of four cases. 56
19606475 2009
6
Congenital skin pedicles with or without amniotic band sequence: Extending the human phenotype resembling mouse disorganization. 56
19449403 2009
7
Clinical and epidemiological studies of amniotic deformity, adhesion, and mutilation (ADAM) sequence in a South American (ECLAMC) population. 56
12655494 2003
8
Constriction bands and limb reduction defects in two newborns with fetal ultrasound evidence for vascular disruption. 56
1481816 1992
9
Familial recurrence of terminal transverse defects of the arm. 56
4017277 1985
10
Discordant amniotic band sequence in monozygotic twins. 56
3887916 1985
11
Familial amniotic bands. 56
6822948 1983
12
Familial amniotic bands. 56
6829612 1983
13
Familial congenital amputations. 56
7202044 1982
14
"ADAM complex" (amniotic deformity, adhesions, mutilations)--a pattern of craniofacial and limb defects. 56
263584 1978
15
A pattern of craniofacial and limb defects secondary to aberrant tissue bands. 56
12119963 1974
16
Revisiting amniotic band sequence: a wide spectrum of manifestations. 52
24247024 2014
17
Body wall defects and amniotic band syndrome in pig (Sus scrofa domesticus). 61
31513296 2020
18
Prenatal diagnosis and clinical significance of cephalocoele - a single institution experience and literature review. 61
32003477 2020
19
Two case reports: Early detection of amniotic band syndrome by adhesion between hand and umbilical cord at 11 to 14 weeks' gestation. 61
31852110 2019
20
Septo-optic dysplasia with amniotic band syndrome sequence: a case report. 61
31839004 2019
21
Case series: Amniotic band sequence with craniofacial abnormalities. 61
31407870 2019
22
Amniotic band syndrome with Tessier number 4 and 7 clefts: a case report. 61
31337519 2019
23
Core outcome set for research studies evaluating treatments for twin-twin transfusion syndrome. 61
30520170 2019
24
Congenital Amniotic Constriction Band of the Pelvis: First Reported Case and Proposed Classification Criterion. 61
31942360 2019
25
[The amniotic band syndrome : a rare and severe malformative pathology]. 61
31373455 2019
26
Unusual facio-upper arm band of a fetus mimicking amniotic band syndrome. 61
30656803 2019
27
Amniotic Band Syndrome Associated with Exencephaly: A Case Report and Literature Review. 61
31516628 2019
28
[Amniotic band syndrome: prenatal diagnosis and management challenges (about 2 cases of lethal malformations)]. 61
31223406 2019
29
Fetoscopic Release of Amniotic Bands Causing Limb Constriction: Case Series and Review of the Literature. 61
30726851 2019
30
Low-cost sensor-integrated 3D-printed personalized prosthetic hands for children with amniotic band syndrome: A case study in sensing pressure distribution on an anatomical human-machine interface (AHMI) using 3D-printed conformal electrode arrays. 61
30921360 2019
31
Amniotic Band Syndrome: A Multidisciplinary Care Approach to the Treatment of a Rare Case. 61
29624436 2019
32
Fetal Surgery and Delayed Cord Clamping: Neonatal Implications. 61
30447809 2018
33
Digital-Facial Translocation in Amniotic Band Sequence: Evidence of the Intrinsic Theory. 61
30106805 2018
34
Amniotic Band Syndrome: A Review of 2 Cases. 61
29634607 2018
35
Tessier number 4 bilateral craniofacial cleft associated with amniotic band syndrome: 22 years of follow-up. 61
29246756 2018
36
The Impact of Microsurgery on Congenital Hand Anomalies Associated with Amniotic Band Syndrome. 61
29876159 2018
37
Retraction Notice to: Amniotic Band Syndrome with Pseudoarthrosis of Tibia and Fibula: A Case Report [J Foot Ankle Surg. 56 (2017) 1121-1124]. 61
29478484 2018
38
Intrauterine Linear Echogenicities in the Gravid Uterus: What Radiologists Should Know. 61
29528829 2018
39
Spontaneous Septostomy in a Twin Pregnancy Causing Fatal Amniotic Band Syndrome. 61
30693129 2018
40
Malformations attributed to the process of vascular disruption. 61
29377641 2018
41
Amniotic Band Syndrome With Pseudoarthrosis of Tibia and Fibula: A Case Report. 61
28623060 2017
42
A rare case of cleft number nine associated with atypical cleft number two. 61
28724820 2017
43
Amniotic band syndrome with pseudoarthrosis of tibia and fibula: A case report. 61
28737311 2017
44
Salvage of Necrotic-Appearing Limb after In Utero Endoscopic Lysis of Constriction Bands. 61
28428904 2017
45
Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso. 61
28292285 2017
46
Management of the Amniotic Band Syndrome with Cleft Palate: Literature Review and Report of a Case. 61
28246561 2017
47
Aplasia cutis congenita and amniotic band syndrome: an uncommon association. 61
28143861 2017
48
Amniotic band syndrome in dichorionic diamniotic twin pregnancy. 61
29904257 2017
49
Case of dominant dystrophic epidermolysis bullosa with amniotic band syndrome. 61
27130450 2017
50
A Rare Case of Two Accessory Maxillae 
with Bilateral Tessier 7 clefts. 61
28232967 2017

Variations for Constricting Bands, Congenital

Expression for Constricting Bands, Congenital

Search GEO for disease gene expression data for Constricting Bands, Congenital.

Pathways for Constricting Bands, Congenital

GO Terms for Constricting Bands, Congenital

Sources for Constricting Bands, Congenital

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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