MCID: CNS002
MIFTS: 36

Constrictive Pericarditis

Categories: Cardiovascular diseases

Aliases & Classifications for Constrictive Pericarditis

MalaCards integrated aliases for Constrictive Pericarditis:

Name: Constrictive Pericarditis 12 15
Pericarditis, Constrictive 44 73
Pericarditis Constrictive 55

Classifications:



External Ids:

Disease Ontology 12 DOID:11481
ICD9CM 35 423.2
MeSH 44 D010494
NCIt 50 C78246
UMLS 73 C0031048

Summaries for Constrictive Pericarditis

MalaCards based summary : Constrictive Pericarditis, also known as pericarditis, constrictive, is related to pericarditis and pericardial effusion. An important gene associated with Constrictive Pericarditis is NPPB (Natriuretic Peptide B). The drugs Coal tar and Colchicine have been mentioned in the context of this disorder. Affiliated tissues include heart, liver and lung.

Wikipedia : 76 Constrictive pericarditis is a medical condition characterized by a thickened, fibrotic pericardium,... more...

Related Diseases for Constrictive Pericarditis

Diseases related to Constrictive Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 142)
# Related Disease Score Top Affiliating Genes
1 pericarditis 31.6 ADA NPPB PRG4
2 pericardial effusion 31.0 ADA NPPB
3 protein-losing enteropathy 29.9 ALB SERPINA1
4 arteries, anomalies of 29.6 ALB NPPB
5 peritonitis 29.3 ADA ALB
6 mulibrey nanism 11.6
7 restrictive cardiomyopathy 10.6
8 hemopericardium 10.4
9 extrapulmonary tuberculosis 10.3 ADA IL1RN
10 rheumatoid arthritis 10.2
11 ascites, chylous 10.2
12 arthritis 10.2
13 cardiac tamponade 10.2
14 pericardial mesothelioma 10.2
15 aneurysm 10.2
16 myocardial infarction 10.1
17 lymphoma 10.1
18 viral meningitis 10.1 ADA SERPINA1
19 atrial heart septal defect 10.1
20 atrial fibrillation 10.1
21 ventricular septal defect 10.1
22 amyloidosis 10.1
23 histidine metabolism disease 10.0 SERPINA1 TRIM37
24 synovitis 10.0 IL1RN PRG4
25 malignant atrophic papulosis 10.0
26 coronary artery anomaly 10.0
27 hepatitis 10.0
28 thrombosis 10.0
29 heart disease 10.0
30 hypertrophic cardiomyopathy 10.0
31 porphyria 10.0
32 mediastinitis 10.0
33 diastolic heart failure 10.0
34 syncope 10.0
35 omenn syndrome 10.0 ADA IL1RN
36 syndrome of inappropriate antidiuretic hormone 10.0 ALB NPPB
37 tricuspid valve insufficiency 10.0 ALB NPPB
38 histidinemia 10.0 SERPINA1 TRIM37
39 gastrointestinal tuberculosis 10.0 ADA ALB
40 abdominal tuberculosis 10.0 ADA ALB
41 renal hypertension 9.9 ALB NPPB
42 tuberculous peritonitis 9.9 ADA ALB
43 pick disease of brain 9.9
44 porphyria cutanea tarda 9.9
45 tetralogy of fallot 9.9
46 thrombophilia due to thrombin defect 9.9
47 melioidosis 9.9
48 liver disease 9.9
49 esophagitis 9.9
50 endomyocardial fibrosis 9.9

Comorbidity relations with Constrictive Pericarditis via Phenotypic Disease Network (PDN):


Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Intermediate Coronary Syndrome
Ischemic Heart Disease Mitral Valve Disease

Graphical network of the top 20 diseases related to Constrictive Pericarditis:



Diseases related to Constrictive Pericarditis

Symptoms & Phenotypes for Constrictive Pericarditis

Drugs & Therapeutics for Constrictive Pericarditis

Drugs for Constrictive Pericarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Coal tar Approved Phase 4,Phase 3 8007-45-2
2
Colchicine Approved Phase 4,Phase 3 64-86-8 6167 2833
3 Antimitotic Agents Phase 4,Phase 3
4 Antirheumatic Agents Phase 4,Phase 3
5 Fibrinolytic Agents Phase 3
6 Plasminogen Phase 3
7 Tissue Plasminogen Activator Phase 3
8
Cabergoline Approved 81409-90-7 54746
9
Dopamine Approved 51-61-6, 62-31-7 681
10
Levodopa Approved 59-92-7 6047
11 Autonomic Agents
12 Dopamine Agents
13 Dopamine agonists
14 Neurotransmitter Agents
15 Peripheral Nervous System Agents
16 Protective Agents

Interventional clinical trials:

(show all 11)
# Name Status NCT ID Phase Drugs
1 Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment. Completed NCT00235079 Phase 4 Colchicine;Placebo
2 Study of Colchicine to Prevent the Postpericardiotomy Syndrome Completed NCT00128427 Phase 3 Colchicine (for 1 month)
3 Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode) Completed NCT00128414 Phase 3 Colchicine (for 6 months);Placebo
4 Study of Colchicine to Treat Acute Pericarditis and Prevent Recurrences Completed NCT00128453 Phase 3 Colchicine (for 3 months);Placebo
5 IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion Recruiting NCT02673879 Phase 3
6 Septal Shift for the Diagnosis of COnstrictive Pericarditis: The Impact of Inspiratory Effort Quantification on Deep Breathing Manoeuvres Unknown status NCT02685371
7 The Association Between Dopamine Agonists and Cardiac Valvulopathy, Fibrosis and Other Cardiopulmonary Events Completed NCT01052948
8 Prognostic Biomarkers in Patients With Acute Pericarditis Recruiting NCT02754713
9 Management of Pericarditis in Children. Not yet recruiting NCT03253315
10 Constrictive Pericarditis in the Adult Congenital Cardiac Population Terminated NCT00268086
11 New Methods to Diagnose Constrictive Pericarditis Withdrawn NCT02027350 Not Applicable

Search NIH Clinical Center for Constrictive Pericarditis

Cochrane evidence based reviews: pericarditis, constrictive

Genetic Tests for Constrictive Pericarditis

Anatomical Context for Constrictive Pericarditis

MalaCards organs/tissues related to Constrictive Pericarditis:

41
Heart, Liver, Lung, Bone, B Cells, Bone Marrow, Brain

Publications for Constrictive Pericarditis

Articles related to Constrictive Pericarditis:

(show top 50) (show all 710)
# Title Authors Year
1
Radical pericardiectomy for chronic constrictive pericarditis. ( 29761570 )
2018
2
Model for end-stage liver disease predicts mortality after pericardiectomy for constrictive pericarditis. ( 29893857 )
2018
3
Difficult diagnosis of heart failure in rheumatoid arthritis: six-year follow-up of constrictive pericarditis. ( 29558019 )
2018
4
A Case of Constrictive Pericarditis Associated with Melioidosis in an Immunocompetent Patient Treated by Pericardiectomy. ( 29551765 )
2018
5
Constrictive Pericarditis. ( 29809259 )
2018
6
Kohlmeier-Degos disease with constrictive pericarditis and atrial fibrillation. ( 29974345 )
2018
7
Successful Total Pericardiectomy for Constrictive Pericarditis in the First Series of Japanese Patients With Mulibrey Nanism. ( 29731032 )
2018
8
Anterior Pericardiectomy for Post Infective Constrictive Pericarditis; Intermediate Term Outcomes. ( 29777668 )
2018
9
Surgical Pericardiectomy for Constrictive Pericarditis: A Single Tertiary Center Experience. ( 29804284 )
2018
10
Clinical features, management and outcome of patients with constrictive pericarditis - Experience from a third world country. ( 29296059 )
2018
11
Constrictive pericarditis: retrospective study of 109 patients. ( 29703105 )
2018
12
Implantable epicardial cardioverter-defibrillator-induced localized constrictive pericarditis. ( 29049636 )
2018
13
Incremental Value of the Tissue Motion of Annular Displacement Derived From Speckle-Tracking Echocardiography for Differentiating Chronic Constrictive Pericarditis From Restrictive Cardiomyopathy. ( 29603321 )
2018
14
Chylothorax and constrictive pericarditis in a woman due to generalized lymphatic anomaly: a case report. ( 29871646 )
2018
15
Constrictive Pericarditis Presenting as Bilateral Pleural Effusion: A Report of Two Cases. ( 29888155 )
2018
16
Longitudinal strain by speckle tracking echocardiography in constrictive pericarditis. ( 29529320 )
2018
17
Constrictive Pericarditis as a Long-term Undetermined Etiology of Ascites and Edema. ( 29321423 )
2018
18
Echocardiography with Elevated Central Venous Pressure Diagnosing Constrictive Pericarditis More Accurately Than Chest CT Scan: A Retrospective Study in 36 Cases. ( 29893679 )
2018
19
Pericardiectomy for Constrictive Pericarditis: An Institution's 21 Years Experience. ( 28780766 )
2017
20
Restrictive Cardiomyopathy or Constrictive Pericarditis: An Unresolved Conundrum. ( 29187041 )
2017
21
Pericardial interstitial cell senescence responsible for pericardial structural remodeling in idiopathic and postsurgical constrictive pericarditis. ( 28456362 )
2017
22
Constrictive pericarditis caused by Cutibacterium (Propionibacterium) acnes: A case report and review of literature. ( 29021959 )
2017
23
Constrictive Pericarditis 5 Months after Radiation Therapy in a 62-Year-Old Woman with Esophageal Cancer. ( 29276442 )
2017
24
Effectiveness and long-term outcomes of surgical intervention for constrictive epicardium in constrictive pericarditis. ( 29080093 )
2017
25
Purulent constrictive pericarditis caused by Salmonella enteritidis in a patient with adult-onset Still's disease: A case report. ( 29390286 )
2017
26
Effusive constrictive pericarditis diagnosed with PET/CT and treated medically. ( 29256890 )
2017
27
Effusive-Constrictive Pericarditis. ( 29025546 )
2017
28
A mysterious cause of constrictive pericarditis: unfolding of the missing link. ( 29293944 )
2017
29
Major vessel venous thrombosis in patients of posttubercular chronic constrictive pericarditis undergoing pericardectomy: A rare scenario. ( 28701604 )
2017
30
Constrictive Pericarditis. ( 29025545 )
2017
31
Uremic pericarditis, pericardial effusion, and constrictive pericarditis in end-stage renal disease: Insights and pathophysiology. ( 28873222 )
2017
32
Visualization of suppressed intraventricular flow by constrictive pericarditis. ( 28800477 )
2017
33
Constrictive Pericarditis: A Practical Clinical Approach. ( 28062267 )
2017
34
Effusive-Constrictive Pericarditis After Pericardiocentesis: Incidence, Associated Findings, and Natural History. ( 28917680 )
2017
35
Constrictive pericarditis: diagnosis, management and clinical outcomes. ( 29175978 )
2017
36
Localized constrictive pericarditis compressing and obstructing the right ventricular inflow tract due to a giant anterior calcified cardiac mass. A case report. ( 28886389 )
2017
37
A Case of Severe Adult-onset Still Disease with Constrictive pericarditis and Pleuritis that Was Successfully Treated with Tocilizumab in Addition to Corticosteroids and Cyclosporin A. ( 29269680 )
2017
38
Surgical Treatment of Constrictive Pericarditis. ( 28461794 )
2017
39
New Cardiac Imaging Algorithms to Diagnose Constrictive Pericarditis Versus Restrictive Cardiomyopathy. ( 28405937 )
2017
40
Chylous Ascites and Chylothorax Caused by Constrictive Pericarditis. ( 29052575 )
2017
41
Importance of Clinical and Laboratory Findings in the Diagnosis and Surgical Prognosis of Patients with Constrictive Pericarditis. ( 28977057 )
2017
42
A Rare Case of Pneumopericardium in the Setting of Tuberculous Constrictive Pericarditis. ( 28634555 )
2017
43
Transient constrictive pericarditis following acute idiopathic pericarditis. AA case report. ( 28827145 )
2017
44
Multidrug Resistant Invasive Nontyphoidal Salmonella Isolated from and Masquerading Healed Tubercular Constrictive Pericarditis and Study of Virulence Markers. ( 28560124 )
2017
45
Progressive Constrictive Pericarditis Shortly after Purulent Pericarditis. ( 29021457 )
2017
46
A clinical enigma of ongoing constrictive pericarditis. ( 28572226 )
2017
47
Experience With Pericardiectomy for Constrictive Pericarditis Over Eight Decades. ( 28760468 )
2017
48
Large ventricular septal defect and coexisting chronic constrictive pericarditis: "reversible Eisenmenger syndrome"-5 years after corrective surgery. ( 28303664 )
2017
49
A case report of combined radical pericardiectomy and beating heart coronary artery bypass grafting in a patient with tubercular chronic constrictive pericarditis with coronary artery disease. ( 28994689 )
2017
50
Constrictive Pericarditis ( 29083701 )
2017

Variations for Constrictive Pericarditis

Expression for Constrictive Pericarditis

Search GEO for disease gene expression data for Constrictive Pericarditis.

Pathways for Constrictive Pericarditis

GO Terms for Constrictive Pericarditis

Cellular components related to Constrictive Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 ALB IL1RN NPPB PRG4 SERPINA1
2 platelet alpha granule lumen GO:0031093 9.16 ALB SERPINA1
3 extracellular space GO:0005615 9.02 ADA ALB IL1RN NPPB SERPINA1

Sources for Constrictive Pericarditis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....