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MCID: CNS002
MIFTS: 42

Constrictive Pericarditis

Categories: Cardiovascular diseases
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Aliases & Classifications for Constrictive Pericarditis

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MalaCards integrated aliases for Constrictive Pericarditis:

Name: Constrictive Pericarditis 11 14 16 75 33
Pericarditis, Constrictive 43 71
Chronic Pericardial Constriction 33
Pericarditis Constrictive 53
Calcareous Pericarditis 33
Pericarditis Calculosa 33
Pick Syndrome of Heart 33
Hutinel-Pick Syndrome 33
Pick Disease of Heart 33
Chronic Tamponade 33
Concretio Cordis 33

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)
ICD11: 33


External Ids:

Disease Ontology 11 DOID:11481
ICD9CM 34 423.2
MeSH 43 D010494
NCIt 49 C78246
SNOMED-CT 68 155340008
ICD11 33 1722995229
UMLS 71 C0031048
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Summaries for Constrictive Pericarditis

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MalaCards based summary: Constrictive Pericarditis, also known as pericarditis, constrictive, is related to pericarditis and hemopericardium. An important gene associated with Constrictive Pericarditis is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Striated muscle contraction pathway. The drug Liver Extracts has been mentioned in the context of this disorder. Affiliated tissues include heart, liver and lung, and related phenotypes are normal and muscle

Wikipedia: 75 Constrictive pericarditis is a medical condition characterized by a thickened, fibrotic pericardium,... more...
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Related Diseases for Constrictive Pericarditis

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Diseases related to Constrictive Pericarditis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 770)
# Related Disease Score Top Affiliating Genes
1 pericarditis 31.7 TNNT2 TNNI3 NPPB IFNG CRP ADA
2 hemopericardium 31.3 TNNI3 NPPB CRP
3 heart septal defect 31.2 TNNT2 NPPB CRP
4 mediastinitis 30.9 CRP ALB ACE
5 protein-losing enteropathy 30.8 TTR SERPINA1 CRP ALB
6 cardiac tamponade 30.8 TNNI3 REN NPPB CRP ALB ADA
7 amyloidosis 30.8 TTR NPPB CRP ALB
8 angina pectoris 30.7 TNNI3 NPPB CRP ACE
9 pleurisy 30.6 IFNG CRP ADA
10 pericardial tuberculosis 30.6 IFNG CRP CALB2 ADA
11 portal hypertension 30.6 REN ALB ACE
12 atrial fibrillation 30.5 TNNI3 NPPB CRP ACE
13 whipple disease 30.5 SERPINA1 CRP ALB
14 actinomycosis 30.5 CRP ALB
15 aortic aneurysm 30.5 REN CRP ALB ACE
16 atrial standstill 1 30.5 TTR NPPB MYBPC3
17 pleural empyema 30.5 CRP ALB ADA
18 liver cirrhosis 30.4 TTR SERPINA1 REN ALB
19 esophageal varix 30.4 SERPINA1 CRP ALB
20 pulmonary tuberculosis 30.4 IFNG CRP ALB ADA
21 pulmonary valve insufficiency 30.4 REN NPPB CRP ACE
22 congenitally corrected transposition of the great arteries 30.3 TNNT2 NPPB
23 acute kidney failure 30.3 REN ALB ACE
24 severe acute respiratory syndrome 30.3 IFNG CRP ACE
25 tricuspid valve insufficiency 30.3 TNNT2 TNNI3 REN NPPB CRP ALB
26 pulmonary hypertension 30.3 SERPINA1 REN NPPB CRP ACE
27 uremia 30.3 REN CRP ALB ACE
28 infective endocarditis 30.3 NPPB CRP ALB ACE
29 pleural tuberculosis 30.3 IFNG CRP ADA
30 cat-scratch disease 30.3 CRP ACE
31 aortic valve disease 1 30.3 REN NPPB CRP ACE
32 aortic dissection 30.3 TNNT2 CRP ALB ACE
33 brucellosis 30.3 IFNG CRP ADA
34 sarcoidosis 1 30.2 IFNG CRP ALB ADA ACE
35 aortic valve insufficiency 30.2 TNNI3 REN NPPB CRP ALB ACE
36 pericardial effusion 30.2 TTR TNNT2 TNNI3 REN NPPB CRP
37 cardiac arrest 30.2 TNNT2 TNNI3 NPPB CRP ACE
38 exanthem 30.2 IFNG CRP ALB ACE
39 cardiomyopathy, familial hypertrophic, 1 30.2 TTN TNNT2 TNNI3 MYBPC3
40 arteries, anomalies of 30.2 TNNI3 REN CRP ALB ACE
41 heart cancer 30.1 TNNI3 CRP CALB2
42 mitral valve stenosis 30.1 TTR REN NPPB CRP ALB ACE
43 miliary tuberculosis 30.1 IFNG CRP ALB ADA ACE
44 peritonitis 30.1 IFNG CRP ALB ADA
45 acquired immunodeficiency syndrome 30.1 IFNG CRP ALB ADA
46 hypokalemia 30.0 REN ALB ACE
47 coronary stenosis 30.0 TNNI3 NPPB CRP ACE
48 pulmonary disease, chronic obstructive 30.0 SERPINA1 NPPB CRP ALB ACE
49 lung disease 30.0 SERPINA1 NPPB IFNG ACE
50 behcet syndrome 30.0 IFNG CRP ALB ADA ACE

Comorbidity relations with Constrictive Pericarditis via Phenotypic Disease Network (PDN):


Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Intermediate Coronary Syndrome
Mitral Valve Disease

Graphical network of the top 20 diseases related to Constrictive Pericarditis:



Diseases related to Constrictive Pericarditis
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Symptoms & Phenotypes for Constrictive Pericarditis

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MGI Mouse Phenotypes related to Constrictive Pericarditis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 9.76 ADA ALB CALB2 IFNG REN SERPINA1
2 muscle MP:0005369 9.65 ADA ALB IFNG MYBPC3 NPPB REN
3 cardiovascular system MP:0005385 9.44 ACE ADA ALB CRP IFNG MYBPC3
Sources

Drugs & Therapeutics for Constrictive Pericarditis

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Drugs for Constrictive Pericarditis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Septal Shift for the Diagnosis of COnstrictive Pericarditis: The Impact of Inspiratory Effort Quantification on Deep Breathing Manoeuvres (SCOPED) Unknown status NCT02685371
2 Characterization of the Liver Parenchyma Using Parametric T1 and T2 Magnetic Resonance Relaxometry Completed NCT04623528
3 Constrictive Pericarditis in the Adult Congenital Cardiac Population Terminated NCT00268086
4 Pressure-Volume Analysis of Constrictive Pericarditis Withdrawn NCT02027350

Search NIH Clinical Center for Constrictive Pericarditis

Cochrane evidence based reviews: pericarditis, constrictive

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Genetic Tests for Constrictive Pericarditis

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Anatomical Context for Constrictive Pericarditis

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Organs/tissues related to Constrictive Pericarditis:

MalaCards : Heart, Liver, Lung, Bone Marrow, Bone, Brain, Small Intestine
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Publications for Constrictive Pericarditis

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Articles related to Constrictive Pericarditis:

(show top 50) (show all 3323)
# Title Authors PMID Year
1
Two cases of restrictive cardiomyopathy in children. 53 62
20035098 2009
2
Utility of BNP in differentiating constrictive pericarditis from restrictive cardiomyopathy in patients with renal insufficiency. 53 62
17923360 2007
3
B-type natriuretic peptide level in a patient with constrictive pericarditis. 53 62
17086538 2006
4
Brain natriuretic peptide levels in constrictive pericarditis and restrictive cardiomyopathy. 53 62
16580543 2006
5
The efficacy of brain natriuretic peptide levels in differentiating constrictive pericarditis from restrictive cardiomyopathy. 53 62
15936624 2005
6
The diagnostic and prognostic value of adenosine deaminase in tuberculous pericarditis. 53 62
8665976 1995
7
Hemodynamic performance of INSPIRIS RESILIA aortic bioprosthesis for severe aortic stenosis: 2-year follow-up in Japanese cohort. 62
35129732 2022
8
Coronavirus disease 2019 vaccination-related pericarditis: a single tertiary-center experience. 62
36166325 2022
9
Ultrasonic Wave Pericardiectomy for IgG4-Related Constrictive Pericarditis. 62
35085526 2022
10
Isolated primary chylopericardium: A rare case report and literature review. 62
36283131 2022
11
A case of transient constrictive pericarditis after COVID-19. 62
35855854 2022
12
A case series of constrictive pericarditis and suggested echocardiographic diagnostic criteria. 62
36345170 2022
13
Pericardiectomy and Pericardial Window for the Treatment of Pericardial Disease in the Contemporary Era. 62
36029363 2022
14
Echocardiographic Differentiation of Pericardial Constriction and Left Ventricular Restriction. 62
36040551 2022
15
Chronic expanding intrapericardial hematoma associated with blunt chest trauma 50 years earlier. 62
36312772 2022
16
Delayed pericardial effusion or tamponade following left atrial appendage closure: A single-center experience. 62
36463080 2022
17
Left Ventricular Angiogram in Constrictive Pericarditis. 62
36201001 2022
18
Constrictive pericarditis following inactivated virus COVID-19 vaccine: a case report with review of the literature. 62
35950151 2022
19
Multimodality Imaging of Constrictive Pericarditis: Pathophysiology and New Concepts. 62
35917048 2022
20
Sclerotherapy of oesophageal varices may induce chronic constrictive pericarditis in children. 62
36220353 2022
21
[Takayasu's disease: an underdiagnosed entity in Sub-Saharan Africa. Report of five Gabonese cases]. 62
36284554 2022
22
A Case of Hodgkin Lymphoma Presenting Initially with Constrictive Pericarditis. 62
36172638 2022
23
Analysis of risk factors of multiorgan failure after pericardiectomy for constrictive pericarditis. 62
36180913 2022
24
Early-onset post-cardiotomy severe constrictive pericarditis: a case report. 62
36072421 2022
25
Erratum: Corrigendum to: Cardiac tamponade and constrictive pericarditis due to Actinomyces meyeri bacterial pericarditis: a case report. 62
36196147 2022
26
Constrictive pericarditis caused by viral myocarditis in children: a brief report. 62
36031615 2022
27
Constrictive pericarditis caused by pericardial substitution using expanded polytetrafluoroethylene. 62
35526126 2022
28
An Unusual Case of Effusive-Constrictive Pericarditis in the Intensive Care Unit. 62
36036044 2022
29
Pneumopericardium with massive pericardial effusion in the setting of tuberculosis constrictive pericarditis: a rare case report. 62
36003225 2022
30
Non-pulmonary Disseminated Tuberculosis Complicated by Constrictive Pericarditis and Cutaneous Gumma. 62
35501629 2022
31
Kaposiform lymphangiomatosis complicated with effusive constrictive pericarditis: a rare systemic malformation involving the heart. 62
35639989 2022
32
Pericardial Manifestations of Thyroid Diseases. 62
35635677 2022
33
Safety Signal between Azacitidine and Pericarditis. 62
35981518 2022
34
Exploring the pathophysiologic basis of constrictive pericarditis of Kohlmeier Degos disease: A case series and review of the literature. 62
35588602 2022
35
Deep venous thrombosis and acute pericarditis associated with severe acute respiratory syndrome coronavirus 2 infection in a Congolese infant with sickle cell disease: a case report. 62
35945602 2022
36
A curious case of pulmonary hypertension in a child. 62
35930167 2022
37
Constrictive pericarditis following mRNA COVID-19 vaccination in a patient with systemic sclerosis. 62
35401886 2022
38
A 15-year-old girl with pericardial tuberculosis complicated by cardiac tamponade: A case report in Somalia. 62
36045809 2022
39
Annular Indentation of the Ventricles in a Stillborn: A Case Report and Literature Review. 62
33305650 2022
40
T cell responses to Mycobacterium indicus pranii immunotherapy and adjunctive glucocorticoid therapy in tuberculous pericarditis. 62
35755143 2022
41
Predictors of low cardiac output after isolated pericardiectomy: an observational study. 62
35974413 2022
42
A 50-Year-Old Man With a History of Recurrent Exudative Right-Sided Pleural Effusion. 62
35983398 2022
43
Descriptive Study of Pericarditis Outcomes in Different Etiologies and Risk Factors: A Retrospective Record Review. 62
36039227 2022
44
Constrictive pericarditis caused by pericardial metastasis from esophageal squamous cell carcinoma: a case report. 62
35669905 2022
45
A case report of pericardial constriction with coexisting severe left main coronary artery disease. 62
35854891 2022
46
Multimodality Imaging for Pericardial Epithelioid Angiosarcoma Presenting With Pericardial Effusion and Constrictive Pericarditis. 62
35656933 2022
47
An eye-opening case report of constrictive pericarditis. 62
35975098 2022
48
Incidentally detected dual right coronary artery in patient with constrictive pericarditis. 62
35236003 2022
49
Cardiac tamponade and constrictive pericarditis due to Actinomyces meyeri bacterial pericarditis: a case report. 62
35821970 2022
50
Pericardiectomy for Constrictive Pericarditis in a Young Patient With Erdheim-Chester Disease. 62
35912320 2022
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Variations for Constrictive Pericarditis

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Expression for Constrictive Pericarditis

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Search GEO for disease gene expression data for Constrictive Pericarditis.
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Pathways for Constrictive Pericarditis

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Pathways related to Constrictive Pericarditis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers 65
11.38 TNNT2 TNNI3 SERPINA1 ALB
2
Striated muscle contraction pathway 74
Show member pathways
 10.79 TTN TNNT2 TNNI3 MYBPC3
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GO Terms for Constrictive Pericarditis

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Cellular components related to Constrictive Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sarcomere GO:0030017 9.63 TNNT2 TNNI3 MYBPC3
2 troponin complex GO:0005861 9.56 TNNT2 TNNI3
3 striated muscle thin filament GO:0005865 9.5 TTN TNNT2
4 cardiac Troponin complex GO:1990584 9.26 TNNT2 TNNI3
5 cardiac myofibril GO:0097512 9.1 TNNT2 TNNI3 MYBPC3

Biological processes related to Constrictive Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 angiotensin maturation GO:0002003 9.46 REN ACE
2 ventricular cardiac muscle tissue morphogenesis GO:0055010 9.43 TNNT2 TNNI3 MYBPC3
3 cardiac muscle contraction GO:0060048 9.23 TTN TNNT2 TNNI3 MYBPC3

Molecular functions related to Constrictive Pericarditis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 troponin C binding GO:0030172 8.92 TNNT2 TNNI3
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Sources for Constrictive Pericarditis

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2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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