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MCID: CNT047
MIFTS: 63

Contact Dermatitis

Categories: Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Contact Dermatitis

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MalaCards integrated aliases for Contact Dermatitis:

Name: Contact Dermatitis 12 76 15 73
Contact Dermatitis/eczema 12
Dermatitis, Venenata 12
Dermatitis Venenata 12
Dermatitis, Contact 44
Dermatitis Contact 55
Contact Eczema 12

Classifications:

MalaCards categories:
Anatomical: Skin diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:2773
MeSH 44 D003877
NCIt 50 C26743
SNOMED-CT 68 40275004
UMLS 73 C0011616
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Summaries for Contact Dermatitis

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MalaCards based summary : Contact Dermatitis, also known as contact dermatitis/eczema, is related to palladium allergic contact dermatitis and nickel allergic contact dermatitis, and has symptoms including pruritus and exanthema. An important gene associated with Contact Dermatitis is FLG (Filaggrin), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Bacitracin and Bronopol have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and t cells, and related phenotypes are hematopoietic system and cellular

Wikipedia : 76 Contact dermatitis is a type of inflammation of the... more...

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Related Diseases for Contact Dermatitis

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Diseases related to Contact Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 483)
# Related Disease Score Top Affiliating Genes
1 palladium allergic contact dermatitis 34.0 CCL17 IL10
2 nickel allergic contact dermatitis 34.0 IFNG IL10 IL4 IL5
3 irritant dermatitis 33.5 FLG IL1A IL1B KRT16 TNF
4 allergic contact dermatitis 32.6 CCL17 CXCL8 CXCR3 FLG ICAM1 IFNG
5 toxicodendron dermatitis 32.2 CXCL8 ICAM1
6 dermatitis 31.5 CCL17 CCL22 FLG IFNG IL31 IL4
7 erythema multiforme 30.6 CCL17 CXCR3 ICAM1 IFNG TNF
8 scabies 30.2 CXCL8 IL10 IL1A
9 discoid lupus erythematosus 30.1 FLG IL10 IVL KRT16
10 alopecia areata 30.0 ICAM1 IFNG IL1A IL1B TNF
11 latex allergy 29.9 FLG IL4 IL5
12 folliculitis 29.8 IFNG IL4 IL5
13 food allergy 29.7 FLG IFNG IL10 IL4 IL5
14 actinic prurigo 29.7 ICAM1 IL1B SELE TNF
15 lepromatous leprosy 29.6 ICAM1 IFNG IL10 TNF
16 cutaneous t cell lymphoma 29.6 CCL17 IFNG IL4
17 cutaneous leishmaniasis 29.5 IFNG IL10 IL4 IL5 TNF
18 allergic hypersensitivity disease 29.4 CCL17 CCL22 IFNG IL10 IL4 IL5
19 lichen planus 29.3 CXCR3 FLG ICAM1 IFNG IL4 IVL
20 pertussis 29.3 IL10 IL1A IL1B IL6 TNF
21 pulpitis 29.3 CXCL8 IL1A IL1B IL6 TNF
22 conjunctivitis 29.3 CXCL8 ICAM1 IFNG IL4 IL5 IL6
23 allergic asthma 29.2 CCL17 IFNG IL10 IL4 IL5
24 ige responsiveness, atopic 29.1 IFNG IL10 IL4 IL5
25 keratoconjunctivitis 28.9 CCL17 CXCL8 ICAM1 IFNG IL4 IL5
26 lung disease 28.9 CXCL8 CXCR3 IL10 IL1B IL5 IL6
27 dermatitis, atopic 28.9 CCL17 CCL22 CXCL8 CXCR3 FLG ICAM1
28 leishmaniasis 28.5 CXCL8 IFNG IL10 IL1A IL1B IL4
29 skin disease 28.3 CCL17 CXCL8 FLG ICAM1 IFNG IL10
30 psoriasis 28.0 CCL17 CCL22 CXCL8 CXCR3 FLG ICAM1
31 asthma 27.9 CCL17 CCL22 CXCL8 FLG ICAM1 IFNG
32 1,4-phenylenediamine allergic contact dermatitis 12.6
33 chromium allergic contact dermatitis 12.6
34 cobalt allergic contact dermatitis 12.5
35 1-chloro-2,4-dinitrobenzene allergic contact dermatitis 12.5
36 4-tert-butylphenol allergic contact dermatitis 12.5
37 benzo[d]isothiazol-3-one allergic contact dermatitis 12.5
38 diphenylmethane-4,4'-diisocyanate allergic contact dermatitis 12.4
39 benzoic acid allergic contact dermatitis 12.4
40 carvone allergic contact dermatitis 12.4
41 neomycin sulfate allergic contact dermatitis 12.4
42 parthenolide allergic contact dermatitis 12.4
43 formaldehyde allergic contact dermatitis 12.4
44 2,4-dinitrophenyl allergic contact dermatitis 12.4
45 potassium dichromate allergic contact dermatitis 12.4
46 n,n'-diphenylthiourea allergic contact dermatitis 12.4
47 n,n'-diethylthiourea allergic contact dermatitis 12.4
48 allergic contact dermatitis of eyelid 12.2
49 photoallergic dermatitis 11.7
50 occupational dermatitis 11.6

Graphical network of the top 20 diseases related to Contact Dermatitis:



Diseases related to Contact Dermatitis
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Symptoms & Phenotypes for Contact Dermatitis

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UMLS symptoms related to Contact Dermatitis:


pruritus, exanthema

MGI Mouse Phenotypes related to Contact Dermatitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.18 CCL17 CXCR3 ICAM1 IFNG IL10 IL1A
2 cellular MP:0005384 10.16 CCL17 CXCR3 ICAM1 IFNG IL10 IL4
3 homeostasis/metabolism MP:0005376 10.15 CXCR3 ICAM1 IFNG IL10 IL1A IL1B
4 cardiovascular system MP:0005385 10.13 CXCR3 ICAM1 IFNG IL10 IL1A IL1B
5 immune system MP:0005387 10.13 CCL17 CCL22 CXCR3 ICAM1 IFNG IL10
6 digestive/alimentary MP:0005381 10.03 ICAM1 IFNG IL10 IL4 IL5 IL6
7 integument MP:0010771 9.96 ICAM1 IFNG IL10 IL1A IL1B IL4
8 liver/biliary system MP:0005370 9.7 IFNG IL10 IL4 IL5 IL6 SELE
9 neoplasm MP:0002006 9.61 CXCR3 ICAM1 IFNG IL10 IL1A IL1B
10 respiratory system MP:0005388 9.23 CXCR3 IFNG IL10 IL4 IL5 IL6
Sources

Drugs & Therapeutics for Contact Dermatitis

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Drugs for Contact Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 158)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bacitracin Approved, Vet_approved Phase 4,Phase 3,Phase 2 1405-87-4 10909430 439542
2
Bronopol Approved Phase 4,Phase 3,Phase 2 52-51-7
3 Parthenolide Approved, Investigational Phase 4,Phase 3,Phase 2 20554-84-1
4
Hydrocortisone acetate Approved, Vet_approved Phase 4,Phase 3 50-03-3
5
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3 50-23-7 5754
6
Glycerol Approved, Investigational Phase 4 56-81-5 753
7
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
8
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Not Applicable 124-94-7 31307
9
Mineral oil Approved, Vet_approved Phase 4,Phase 3 8042-47-5
10
Clobetasol Approved, Experimental, Investigational Phase 4,Phase 3,Phase 1 25122-46-7, 25122-41-2 5311051 32798
11
Povidone Approved Phase 4,Phase 3,Phase 2,Not Applicable 9003-39-8
12
Clindamycin Approved, Vet_approved Phase 4 18323-44-9 29029
13
Benzoyl peroxide Approved Phase 4 94-36-0 7187
14
Adapalene Approved Phase 4 106685-40-9 60164
15 sodium thiosulfate Phase 4,Phase 3
16 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Not Applicable
17 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
18 Cortisol succinate Phase 4,Phase 3
19 Gold Sodium Thiosulfate Phase 4,Phase 3
20 Dermatologic Agents Phase 4,Phase 3,Phase 1,Not Applicable
21 Hydrocortisone 17-butyrate 21-propionate Phase 4,Phase 3
22 Hydrocortisone-17-butyrate Phase 4,Phase 3
23 Antioxidants Phase 4,Phase 3
24 Anti-Infective Agents, Local Phase 4,Phase 3,Phase 2,Not Applicable
25 Antidotes Phase 4,Phase 3
26 Antitubercular Agents Phase 4,Phase 3,Phase 2
27 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
28 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2
29 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Not Applicable
30 Analgesics Phase 4,Phase 3,Phase 2
31 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Not Applicable
32 Chelating Agents Phase 4,Phase 3
33 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
34 Protective Agents Phase 4,Phase 3,Phase 1
35 triamcinolone acetonide Phase 4,Phase 2,Not Applicable
36 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Triamcinolone diacetate Phase 4,Phase 2,Not Applicable
38 Calcineurin Inhibitors Phase 4
39 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
40 Immunosuppressive Agents Phase 4,Phase 2,Not Applicable
41 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Triamcinolone hexacetonide Phase 4,Phase 2,Not Applicable
43 Emollients Phase 4,Phase 3,Phase 1,Not Applicable
44 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
45 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
46 Clindamycin palmitate Phase 4
47 Adapalene, Benzoyl Peroxide Drug Combination Phase 4
48 Clindamycin phosphate Phase 4
49
Betamethasone Approved, Vet_approved Phase 3,Not Applicable 378-44-9 9782
50
Prednisolone phosphate Approved, Vet_approved Phase 3,Phase 1 302-25-0

Interventional clinical trials:

(show top 50) (show all 128)
# Name Status NCT ID Phase Drugs
1 Clinical Evaluation of T.R.U.E. Test Allergens in Children an Adolescents Unknown status NCT01797562 Phase 4 T.R.U.E. Test Panel 3.2
2 Quaternium-15, Use Test Unknown status NCT00311454 Phase 4 T.R.U.E.Test
3 Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)
4 Study of the Safety and Efficacy of Tacrolimus Ointment in Treating Chronic Allergic Contact Dermatitis Completed NCT00667056 Phase 4 tacrolimus ointment;placebo ointment
5 Bioequivalence of Ethylenediamine Dihydrochloride Study Completed NCT01798589 Phase 4 Ethylenediamine dihydrochloride
6 A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne Completed NCT00887484 Phase 4 BENZOYL PEROXIDE/ CLINDAMYCIN;BENZOYL PEROXIDE/ ADAPALENE
7 A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne Completed NCT00964223 Phase 4 Clindamycin and benzoyl peroxide gel (Duac® Topical Gel);benzoyl peroxide and adapalene gel (EPIDUOâ„¢ Gel)
8 Topic Compatibility Lactoserum (Dermacyd Delicata - New Fragrance) Completed NCT00497692 Phase 4 Lactoserum
9 Dermacyd Infantile (Lactic Acid)- Compatibility. Completed NCT00881374 Phase 4 LACTIC ACID(ND)
10 Dermacyd Infantile (Lactic Acid) - Photo Evaluation. Completed NCT00881348 Phase 4 LACTIC ACID(ND)
11 Safety and Efficacy Study of Altabax Ointment in the Treatment of Secondarily Infected Atopic Dermatitis Completed NCT01064947 Phase 4 Retapamulin 1%
12 Clinical Evaluation of T.R.U.E. TEST in Children and Adolescents Completed NCT00795951 Phase 4
13 Tape Versus Semirigid Versus Lace-up Ankle Support in the Treatment of Acute Lateral Ankle Ligament Injury. Completed NCT01126242 Phase 4
14 Anti-IL-17 a New Treatment for Contact Dermatititis Unknown status NCT02778711 Phase 3 secukinumab
15 Efficacy and Tolerability of Prednisolone Acetate 0.5% Cream Versus Betamethasone Valerate 0.1% Cream in Cortisosensitive Dermatosis Unknown status NCT01011621 Phase 3 0.5% prednisolone acetate cream;0.1% betamethasone valerate cream
16 Topical Timolol for Superficial Infantile Hemangioma Unknown status NCT01685398 Phase 3 0.5% timolol maleate eye drop;Normal saline
17 Clinical Evaluation of T.R.U.E. TEST® : Safety and Efficacy Completed NCT00640614 Phase 3
18 Topic Compatibility Dermacyd Delicata - New Fragrance - Lactoserum - Hygiene Completed NCT00380991 Phase 3 lactoserum
19 Topic Compatibility Dermacyd Wipes - Lactoserum - Hygiene Completed NCT00371852 Phase 3 lactoserum
20 Dermacyd Teen Care Tangerina Mix - Compatibility Completed NCT00761800 Phase 3 Lactic acid
21 Dermacyd Silver Floral (Lactic Acid) - Compatibility. Completed NCT00933712 Phase 3 LACTIC ACID(ND)
22 Dermacyd Silver Floral (Lactic Acid) - Compatibility - Stay on Floral Completed NCT00933504 Phase 3 LACTIC ACID(ND)
23 Dermacyd Silver Frutal (Lactic Acid) - Compatibility. Completed NCT00933946 Phase 3 LACTIC ACID(ND)
24 Dermacyd PH_DESILSTY_FR (Lactic Acid) - Compatibility - Stay on Frutal Completed NCT00933907 Phase 3 LACTIC ACID(ND)
25 Dermacyd PH_DETINLYN (Lactic Acid) Tangerine Mix - Compatibility Completed NCT00786097 Phase 3 Dermacyd PH_DETINLYN (Lactic Acid)
26 Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Compatibility Completed NCT00785681 Phase 3 Dermacyd PH_DETINBACK (Lactic Acid)
27 Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Compatibility Completed NCT00785655 Phase 3 Dermacyd PH_DETINLYN (Lactic Acid)
28 Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid)- Compatibility Completed NCT00784160 Phase 3 Lactic Acid (Dermacyd PH_DETINBACK Tangerine Mix)
29 Dermacyd Breeze (Lactic Acid) Pocket BR - Compatibility Completed NCT00784121 Phase 3 Lactic Acid
30 Dermacyd Femina (Lactic Acid) Pocket BR - Compatibility Completed NCT00783861 Phase 3 Lactic Acid
31 Dermatological Evaluation of Topic Compatibility-Dermacyd Tina Gel Tangerina Mix Completed NCT00669058 Phase 3 Lactic acid (Dermacid)
32 Dermatological Evaluation of Topic Compatibility-Dermacyd Tina Gel Sweet Flower Completed NCT00668668 Phase 3 Lactic acid (Dermacid)
33 Dermatological Evaluation of Topic Compatibility - Dermacyd Breeze Completed NCT00668577 Phase 3 Lactic acid (Dermacid)
34 Dermatological Evaluation of Topic Compatibility-Dermacyd Delicata Pocket BR Completed NCT00668460 Phase 3 Lactic acid (Dermacid)
35 Dermacyd Silver Floral (Lactic Acid) - Photo Evaluation Completed NCT00932984 Phase 3 LACTIC ACID(ND)
36 Dermacyd PH_DESILSTY_FR (Lactic Acid) - Photo Evaluation - Stay on Frutal Completed NCT00933257 Phase 3 LACTIC ACID(ND)
37 Dermacyd PH_DESILSTY_FL (Lactic Acid) - Photo Evaluation - Stay on Floral Completed NCT00933842 Phase 3 LACTIC ACID(ND)
38 Dermacyd Silver Frutal (Lactic Acid) - Photo Evaluation. Completed NCT00933075 Phase 3 LACTIC ACID(ND)
39 Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Photo Avaluation Completed NCT00785720 Phase 3 Dermacyd PH_DETINBACK (Lactic Acid)
40 Dermacyd Tina Gel Tangerina Mix - Photo Evaluation Completed NCT00668889 Phase 3 Lactic acid (Dermacid)
41 Dermacyd Tina Gel Sweet Flower - Photo Evaluation Completed NCT00668629 Phase 3 Lactic acid (Dermacid)
42 Dermacyd Delicata Breeze - Photo Evaluation Completed NCT00668486 Phase 3 Lactic acid (Dermacid)
43 Dermacyd Delicata Pocket BR - Photo Evaluation Completed NCT00668226 Phase 3 Lactic acid (Dermacid)
44 Dermacyd PH_DETINLYN (Lactic Acid) Sweet Flower - Photo Evaluation. Completed NCT00785590 Phase 3 Dermacyd PH_DETINLYN (Lactic Acid)
45 Dermacyd PH_DETINLYN Tangerine Mix (Lactic Acid) - Photo Evaluation Completed NCT00784056 Phase 3 Lactic Acid (Dermacyd PH_DETINLYN Tangerine Mix)
46 Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid) - Photo Evaluation Completed NCT00783666 Phase 3 Lactic Acid (Dermacyd PH_DETINBACK Tangerine Mix)
47 Dermacyd Femina (Lactic Acid) Pocket BR - Photo Evaluation Completed NCT00783640 Phase 3 Lactic Acid
48 Dermacyd Femina (Lactic Acid) - Photo Dermatological Evaluation of the Irritation and Sensitivity Potential. Completed NCT00705744 Phase 3 Lactic acid (Dermacyd Femina)
49 Dermacyd Femina Delicata (Lactic Acid)- Photo Dermatological Evaluation of the Irritation and Sensitivity Potential Completed NCT00705276 Phase 3 Lactic acid (Dermacyd Femina Delicata)
50 A Trial Comparing the Efficacy and Safety of Open Dressing With Petrolatum Jelly vs. Standard Gauze Dressing With Silver Sulfadiazine Completed NCT02109718 Phase 3 Open Dressings with Petrolatum Jelly;Silver Sulfadiazine Gauze Dressing Group

Search NIH Clinical Center for Contact Dermatitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: dermatitis, contact

Sources

Genetic Tests for Contact Dermatitis

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Anatomical Context for Contact Dermatitis

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MalaCards organs/tissues related to Contact Dermatitis:

41
Testes, Skin, T Cells, Eye, Lung, Bone, Breast
Sources

Publications for Contact Dermatitis

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Articles related to Contact Dermatitis:

(show top 50) (show all 1935)
# Title Authors Year
1
Occupational allergic contact dermatitis caused by colophonium. ( 30229960 )
2019
2
Allergic contact dermatitis caused by isopropyl lauroyl sarcosinate. ( 30238468 )
2019
3
Occupational allergic contact dermatitis caused by cobalt in machine oil. ( 30246382 )
2019
4
"Crossed" allergic contact dermatitis caused by oxidized vitamin K1 in a patient previously sensitized to non-oxidized vitamin K1. ( 30264888 )
2019
5
Allergic contact dermatitis caused by vinylpyrrolidone/eicosene copolymer in a sunscreen. ( 30304757 )
2019
6
Allergic contact dermatitis caused by Dermabond in a paediatric patient undergoing skin surgery. ( 30304758 )
2019
7
Allergic contact dermatitis caused by clindamycin. ( 30311633 )
2019
8
Occupational airborne allergic contact dermatitis caused by N-(4-hydroxyphenyl)benzenesulfonamide. ( 30334269 )
2019
9
Tertiary prevention of occupational skin diseases: Prevalence of allergic contact dermatitis and pattern of patch test results. ( 30506828 )
2019
10
Severe contact dermatitis caused by urushiol in Japanese lacquer. ( 30175848 )
2019
11
What's the "buzz" about propolis? Propolis-induced systemic contact dermatitis. ( 30311211 )
2019
12
Contact Dermatitis: Emerging Trends. ( 30466685 )
2019
13
Allergic contact dermatitis caused by octylisothiazolinone in a leather sofa. ( 29790173 )
2018
14
Textile contact dermatitis caused by octylisothiazolinone in compression stockings. ( 29399813 )
2018
15
Chemokine Signaling in Allergic Contact Dermatitis: Toward Targeted Therapies. ( 29939854 )
2018
16
Allergic contact dermatitis caused by acrylic-based medical dressings and adhesives. ( 29888412 )
2018
17
Declining prevalence of allergic contact dermatitis caused by tosylamide formaldehyde resin in nail polish. ( 29726606 )
2018
18
Pesticide contact dermatitis in agricultural workers of Himachal Pradesh (India). ( 29974480 )
2018
19
Allergic contact dermatitis resulting from cetyl PEG/PPG-10/1 dimethicone in a deodorant cream. ( 29430705 )
2018
20
Pediatric "pet consort dermatitis"-Allergic contact dermatitis from transfer of bronopol from a pet cat. ( 29943851 )
2018
21
Allergic contact dermatitis caused by hydroxyacetophenone in a face cream. ( 29341188 )
2018
22
Allergic contact dermatitis caused by triethylenetetramine: the glue is the clue. ( 29392782 )
2018
23
Glove-Related Allergic Contact Dermatitis. ( 29901500 )
2018
24
Kumkum-induced allergic contact dermatitis: Are we missing the actual culprit? ( 29393081 )
2018
25
Occupational allergic contact dermatitis caused by antibiotics in healthcare workersA -A relationship with non-immediate drug eruptions. ( 29399806 )
2018
26
Involvement of the Negative Feedback of IL-33 Signaling in the Anti-Inflammatory Effect of Electro-acupuncture on Allergic Contact Dermatitis via Targeting MicroRNA-155 in Mast Cells. ( 29404871 )
2018
27
Contact dermatitis with concomitant contact urticaria syndrome due to multiple ingredients of oxidative hair dye. ( 29866587 )
2018
28
Chromium(III) release from chromium-tanned leather elicits allergic contact dermatitis: a use test study. ( 29322530 )
2018
29
Silkworm dropping extract ameliorate trimellitic anhydride-induced allergic contact dermatitis by regulating Th1/Th2 immune response. ( 29806566 )
2018
30
Boat builders' occupational contact dermatitis - 11-year data from the Finnish register of occupational diseases. ( 29383726 )
2018
31
Short contact with nickel causes allergic contact dermatitis: an experimental study. ( 29959775 )
2018
32
Severe allergic contact dermatitis mimicking angioedema caused by propolis used as a traditional remedy. ( 29845630 )
2018
33
Allergic contact dermatitis caused by benzyl salicylate in hair products. ( 29943414 )
2018
34
Food-Related Contact Dermatitis, Contact Urticaria, and Atopy Patch Test with Food. ( 29881951 )
2018
35
Contact Buzz: Allergic Contact Dermatitis to Cannabis. ( 29933254 )
2018
36
A case of allergic contact dermatitis caused by Disperse Blue dye in ultrasound gel. ( 29766523 )
2018
37
Systemic contact dermatitis caused by inhalation of epoxy resin in industrial waste vapour. ( 29869335 )
2018
38
Contact Dermatitis Due to Black Pepper Extract Used to Treat Vitiligo. ( 29937061 )
2018
39
Relapsing polyisoprene glove allergic contact dermatitis: Another call for more complete glove package label declaration. ( 29785753 )
2018
40
First report of allergic contact dermatitis caused by sorbitan caprylate. ( 29341184 )
2018
41
Pediatric Baseline Patch Test Series: Initial Findings of the Pediatric Contact Dermatitis Workgroup. ( 29933256 )
2018
42
Occupational allergic contact dermatitis caused by nickel in embroidery needles. ( 29781177 )
2018
43
Footwear Contact Dermatitis: A Prospective Cross-Sectional Study of 108 Outpatients from Delhi, India. ( 29911525 )
2018
44
Allergic contact dermatitis from formaldehyde mimicking impetigo and initiating rosacea. ( 29611264 )
2018
45
Innate immunity and effector and regulatory mechanisms involved in allergic contact dermatitis. ( 29723367 )
2018
46
Positive Patch Test to Metals in a Patient With Symmetrical Intertriginous Skin Eruptions: Systemic Contact Dermatitis or Lichen Planus Pigmentosus Inversus? ( 29570487 )
2018
47
A case of contact dermatitis and contact urticaria syndrome due to multiple allergens observed in a professional baseball player. ( 29395964 )
2018
48
Possible role of regional variation in allergic contact dermatitis: case report. ( 29430710 )
2018
49
Anti-pruritic and anti-inflammatory effects of oxymatrine in a mouse model of allergic contact dermatitis. ( 29903654 )
2018
50
A novel case of a brush with discomfort: allergic contact dermatitis caused by mercaptobenzothiazole in rubber components of a toothbrush. ( 29446120 )
2018
Sources

Variations for Contact Dermatitis

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Expression for Contact Dermatitis

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Search GEO for disease gene expression data for Contact Dermatitis.
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Pathways for Contact Dermatitis

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Pathways related to Contact Dermatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 86)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 66
Show member pathways
 14.1 CCL22 CXCL8 ICAM1 IFNG IL10 IL1A
2
ERK Signaling 64
Show member pathways
 13.94 CCL17 CCL22 CXCL8 CXCR3 IL10 IL1A
3
PEDF Induced Signaling 64
Show member pathways
 13.8 CCL17 CCL22 CXCL8 CXCR3 IFNG IL10
4
TGF-Beta Pathway 64
Show member pathways
 13.67 CCL17 CCL22 CXCL8 ICAM1 IFNG IL10
5
Akt Signaling 64
Show member pathways
 13.55 CCL17 CCL22 CXCL8 CXCR3 IL10 IL1A
6
Cytokine Signaling in Immune system 66
Show member pathways
 13.49 CCL22 CXCL8 ICAM1 IFNG IL10 IL1A
7
PAK Pathway 64
Show member pathways
 13.43 CCL17 CCL22 CXCL8 CXCR3 IL10 IL1A
8
Toll-like Receptor Signaling Pathway 37 1
Show member pathways
 13.08 CXCL8 IFNG IL10 IL1B IL6 TNF
9
Allograft rejection 1 37
Show member pathways
 13.03 CXCL8 ICAM1 IFNG IL10 IL1A IL1B
10
Influenza A 37
Show member pathways
 12.96 CXCL8 ICAM1 IFNG IL1A IL1B IL4
11
Pathways in cancer 37
12.88 CXCL8 IFNG IL4 IL5 IL6
12
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways 66
Show member pathways
 12.82 CXCL8 IFNG IL1B IL6 TNF
13
Th17 cell differentiation 37
Show member pathways
 12.77 IFNG IL10 IL1A IL1B IL4 IL5
14
Immune response IL-23 signaling pathway 22
Show member pathways
 12.68 IFNG IL10 IL1B IL6 TNF
15
NF-kappaB Signaling 4
12.66 IFNG IL10 IL1B IL4 TNF
16
T cell receptor signaling pathway 37
Show member pathways
 12.62 IFNG IL10 IL1A IL1B IL4 IL5
17
Immune response Role of DAP12 receptors in NK cells 22
Show member pathways
 12.54 ICAM1 IFNG IL4 TNF
18
IL-17 Family Signaling Pathways 65
Show member pathways
 12.52 CCL17 CXCL8 IFNG IL1B IL4 IL5
19
Selenium Micronutrient Network 1
Show member pathways
 12.51 ICAM1 IFNG IL1B IL4 IL6 TNF
20
JAK-STAT signaling pathway (KEGG) 37
Show member pathways
 12.5 IFNG IL10 IL4 IL5 IL6
21
Toll Comparative Pathway 64
Show member pathways
 12.48 CXCL8 IFNG IL1A IL1B IL6 TNF
22
Toxoplasmosis 37
Show member pathways
 12.44 IFNG IL10 IL1A IL1B IL4 TNF
23
Immune response IFN alpha/beta signaling pathway 22
Show member pathways
 12.43 CXCL8 IFNG IL10 IL1A IL1B IL4
24
Tuberculosis 37
12.42 IFNG IL10 IL1A IL1B IL6 TNF
25
C-type lectin receptor signaling pathway 37
Show member pathways
 12.39 CCL17 CCL22 IL10 IL1B IL6 TNF
26
IL-1 Family Signaling Pathways 65
Show member pathways
 12.37 CXCL8 IL1A IL1B IL6 TNF
27
G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins 22
Show member pathways
 12.37 CCL17 CCL22 CXCL8 CXCR3 ICAM1 IL1A
28
Bacterial infections in CF airways 22
Show member pathways
 12.37 CXCL8 IFNG IL1B IL4 IL6 TNF
29
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
12.36 CXCL8 IL10 IL1A IL1B IL6 TNF
30
Diseases associated with the TLR signaling cascade 66
Show member pathways
 12.34 CXCL8 IL1A IL6 TNF
31
Necroptosis 37
Show member pathways
 12.29 IFNG IL1A IL1B TNF
32
Fluid shear stress and atherosclerosis 37
12.29 ICAM1 IFNG IL1A IL1B SELE TNF
33
Th1 Differentiation Pathway 65
Show member pathways
 12.22 IFNG IL10 IL1B IL6 TNF
34
Microglia Activation During Neuroinflammation: Overview 65
Show member pathways
 12.21 IFNG IL1B IL4 IL6 TNF
35
Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers 65
12.2 IFNG IL10 IL4 IL5 IL6 TNF
36
Immune response IFN gamma signaling pathway 22
Show member pathways
 12.19 CCL17 CCL22 CXCL8 ICAM1 IFNG IL10
37
Spinal Cord Injury 1
12.18 CXCL8 ICAM1 IFNG IL1A IL1B IL4
38
Osteoclast differentiation 37
12.15 IFNG IL1A IL1B TNF
39
TNF signaling pathway 37
12.14 ICAM1 IL1B IL6 SELE TNF
40
Senescence and Autophagy in Cancer 1
12.12 CXCL8 IFNG IL1A IL1B IL6
41
Hematopoietic cell lineage 37
12.11 IL1A IL1B IL4 IL5 IL6 TNF
42
Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions 65
Show member pathways
 12.1 CCL17 CCL22 CXCL8 CXCR3
43
Amoebiasis 37
12.1 CXCL8 IFNG IL10 IL1B IL6 TNF
44
AGE-RAGE signaling pathway in diabetic complications 37
12.1 CXCL8 ICAM1 IL1A IL1B IL6 SELE
45
Rheumatoid arthritis 37
12.05 CXCL8 ICAM1 IFNG IL1A IL1B IL6
46
Salmonella infection (KEGG) 37
12.03 CXCL8 IFNG IL1A IL1B IL6
47
NF-kappa B signaling pathway 37
12.01 CXCL8 ICAM1 IL1B TNF
48
Glucocorticoid receptor regulatory network 1
11.99 CXCL8 ICAM1 IFNG IL4 IL5 IL6
49
Pertussis 37
11.98 CXCL8 IL10 IL1A IL1B IL6 TNF
50
Innate Lymphoid Cell Differentiation Pathways 65
11.97 CXCR3 IFNG IL10 IL1B IL4 IL5
Sources

GO Terms for Contact Dermatitis

About this section

Cellular components related to Contact Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 CCL17 CCL22 CXCL8 IFNG IL10 IL1A
2 extracellular space GO:0005615 9.47 CCL17 CCL22 CXCL8 ICAM1 IFNG IL10

Biological processes related to Contact Dermatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.98 ICAM1 IL1B SELE TNF
2 response to lipopolysaccharide GO:0032496 9.97 ICAM1 IL10 IL1B SELE
3 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.97 CCL17 CCL22 ICAM1 IL1B TNF
4 chemotaxis GO:0006935 9.96 CCL17 CCL22 CXCL8 CXCR3
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.94 ICAM1 IL1B IL6 TNF
6 inflammatory response GO:0006954 9.93 CCL17 CCL22 CXCL8 CXCR3 IL10 IL1A
7 cellular response to tumor necrosis factor GO:0071356 9.91 CCL17 CCL22 CXCL8 ICAM1
8 cellular response to interferon-gamma GO:0071346 9.9 CCL17 CCL22 ICAM1
9 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.9 ICAM1 IL5 IL6
10 calcium-mediated signaling GO:0019722 9.89 CXCL8 CXCR3 SELE
11 keratinocyte differentiation GO:0030216 9.89 FLG IVL KRT16
12 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.88 IFNG IL4 IL6
13 regulation of insulin secretion GO:0050796 9.88 IFNG IL1B TNF
14 positive regulation of T cell proliferation GO:0042102 9.87 IL1B IL4 IL6
15 neutrophil chemotaxis GO:0030593 9.87 CCL17 CCL22 CXCL8 IL1B
16 positive regulation of interleukin-6 production GO:0032755 9.86 IL1B IL6 TNF
17 humoral immune response GO:0006959 9.85 IFNG IL6 TNF
18 cellular response to interleukin-1 GO:0071347 9.85 CCL17 CCL22 CXCL8 ICAM1
19 monocyte chemotaxis GO:0002548 9.83 CCL17 CCL22 IL6
20 positive regulation of DNA-binding transcription factor activity GO:0051091 9.83 IL10 IL1B IL5 IL6 TNF
21 chemokine-mediated signaling pathway GO:0070098 9.81 CCL17 CCL22 CXCL8 CXCR3
22 negative regulation of endothelial cell apoptotic process GO:2000352 9.8 ICAM1 IL10 IL4
23 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.8 IL1A IL1B TNF
24 cellular response to lipopolysaccharide GO:0071222 9.8 CXCL8 ICAM1 IL10 IL1B IL6 TNF
25 response to glucocorticoid GO:0051384 9.78 IL10 IL1B IL6 TNF
26 positive regulation of cytokine secretion GO:0050715 9.77 IL10 IL1A TNF
27 negative regulation of neurogenesis GO:0050768 9.76 IL1B IL6 TNF
28 positive regulation of nitric oxide biosynthetic process GO:0045429 9.76 ICAM1 IFNG IL1B TNF
29 regulation of signaling receptor activity GO:0010469 9.73 CCL17 CCL22 CXCL8 IFNG IL10 IL1A
30 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.72 IL1A IL1B
31 positive regulation of immunoglobulin secretion GO:0051024 9.72 IL5 IL6
32 positive regulation of podosome assembly GO:0071803 9.72 IL5 TNF
33 response to molecule of bacterial origin GO:0002237 9.72 CXCL8 IL10
34 negative regulation of lipid storage GO:0010888 9.71 IL6 TNF
35 endothelial cell apoptotic process GO:0072577 9.71 IL10 TNF
36 positive regulation of glial cell proliferation GO:0060252 9.71 IL1B IL6 TNF
37 positive regulation of chemokine biosynthetic process GO:0045080 9.7 IL1B TNF
38 ectopic germ cell programmed cell death GO:0035234 9.7 IL1A IL1B
39 positive regulation of MHC class II biosynthetic process GO:0045348 9.7 IL10 IL4
40 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.7 IFNG IL1B TNF
41 regulation of establishment of endothelial barrier GO:1903140 9.69 IL1B TNF
42 negative regulation of cytokine secretion involved in immune response GO:0002740 9.68 IL10 TNF
43 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.67 ICAM1 TNF
44 positive regulation of fever generation GO:0031622 9.67 IL1B TNF
45 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.67 IL10 IL1B TNF
46 chronic inflammatory response to antigenic stimulus GO:0002439 9.65 IL1B TNF
47 regulation of isotype switching GO:0045191 9.65 IL10 IL4
48 sequestering of triglyceride GO:0030730 9.65 IL1B TNF
49 type 2 immune response GO:0042092 9.64 IL10 IL4
50 fever generation GO:0001660 9.62 IL1A IL1B

Molecular functions related to Contact Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.4 CCL17 CCL22 CXCL8 IFNG IL10 IL1A
2 chemokine activity GO:0008009 9.33 CCL17 CCL22 CXCL8
3 interleukin-1 receptor binding GO:0005149 9.26 IL1A IL1B
4 growth factor activity GO:0008083 9.26 IL10 IL4 IL5 IL6
Sources

Sources for Contact Dermatitis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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