MCID: CNT001
MIFTS: 40

Contagious Pustular Dermatitis

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Contagious Pustular Dermatitis

MalaCards integrated aliases for Contagious Pustular Dermatitis:

Name: Contagious Pustular Dermatitis 12 15 17
Ecthyma, Contagious 12 45 74
Ecthyma Contagiosum 12
Thistle Disease 12
Scabby Mouth 12
Sheep Pox 12
Orf 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8771
ICD9CM 36 051.2
MeSH 45 D004474
SNOMED-CT 69 74050005
ICD10 34 B08.02
UMLS 74 C0013570

Summaries for Contagious Pustular Dermatitis

Disease Ontology : 12 A viral infectious disease that results in infection located in skin, has material basis in Orf virus, which is transmitted by contact with infected or recently vaccinated animals, or transmitted by fomites carrying the virus. The infection has symptom lesions on the finger, hand, arm, face, and penis.

MalaCards based summary : Contagious Pustular Dermatitis, also known as ecthyma, contagious, is related to milker's nodule and dermatitis, and has symptoms including lesions on the finger An important gene associated with Contagious Pustular Dermatitis is LAGE3 (L Antigen Family Member 3), and among its related pathways/superpathways is Cardiac muscle contraction. The drugs Amphetamine and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and liver.

Wikipedia : 77 Orf is an exanthemous disease caused by a parapox virus and occurring primarily in sheep and goats. It... more...

Related Diseases for Contagious Pustular Dermatitis

Diseases related to Contagious Pustular Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 milker's nodule 11.5
2 dermatitis 10.9
3 skin disease 10.4
4 erythema multiforme 10.3
5 ecthyma 10.3
6 human herpesvirus 8 10.2
7 bronchitis 10.2
8 chickenpox 10.2
9 kaposi sarcoma 10.2
10 sarcoma 10.2
11 severe acute respiratory syndrome 10.2
12 papilloma 10.2
13 vaccinia 10.2
14 leukemia 10.1
15 t-cell leukemia 10.1
16 stomatitis 10.1
17 deafness-infertility syndrome 10.1
18 hepatitis 10.0
19 gastroenteritis 10.0
20 epidermolysis bullosa 10.0
21 epidermolysis bullosa acquisita 10.0
22 bullous pemphigoid 10.0
23 bowenoid papulosis 10.0
24 platelet membrane fluidity 9.9
25 burns 9.9
26 diarrhea 9.9
27 hepatitis e 9.9
28 influenza 9.9
29 candida glabrata 9.9
30 isolated complex iii deficiency 9.9 CYC1 MT-CYB
31 radin blood group antigen 9.8
32 blood group--ul system 9.8
33 hypotrichosis 4 9.8
34 marfan syndrome 9.8
35 ocular cicatricial pemphigoid 9.8
36 6-phosphogluconolactonase deficiency 9.8
37 triiodothyronine receptor auxiliary protein 9.8
38 suppressor of tumorigenicity 3 9.8
39 myeloma, multiple 9.8
40 spastic ataxia, charlevoix-saguenay type 9.8
41 dermatitis, atopic 9.8
42 psoriatic arthritis 9.8
43 hepatitis c virus 9.8
44 infantile liver failure syndrome 1 9.8
45 al-raqad syndrome 9.8
46 acute liver failure 9.8
47 arthritis 9.8
48 hepatitis b 9.8
49 systemic scleroderma 9.8
50 erysipeloid 9.8

Graphical network of the top 20 diseases related to Contagious Pustular Dermatitis:



Diseases related to Contagious Pustular Dermatitis

Symptoms & Phenotypes for Contagious Pustular Dermatitis

Symptoms:

12
  • lesions on the finger

Drugs & Therapeutics for Contagious Pustular Dermatitis

Drugs for Contagious Pustular Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amphetamine Approved, Illicit, Investigational Phase 4 300-62-9 3007 5826
2
Dopamine Approved Phase 4 62-31-7, 51-61-6 681
3
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
4
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
5 Adrenergic Agents Phase 4
6 Neurotransmitter Agents Phase 4
7 Antihypertensive Agents Phase 4
8 Adrenergic Agonists Phase 4
9 Dopamine Uptake Inhibitors Phase 4
10 Adrenergic alpha-Agonists Phase 4
11 Sympathomimetics Phase 4
12 adderall Phase 4
13 Neurotransmitter Uptake Inhibitors Phase 4
14 Central Nervous System Stimulants Phase 4
15 Peripheral Nervous System Agents Phase 4,Phase 1
16 Atomoxetine Hydrochloride Phase 4
17 Dopamine Agents Phase 4
18 Adrenergic alpha-2 Receptor Agonists Phase 4
19 Autonomic Agents Phase 4
20
Irinotecan Approved, Investigational Phase 3 100286-90-6, 97682-44-5 60838
21
Deferiprone Approved Phase 2, Phase 3 30652-11-0 2972
22
Iron Approved, Experimental Phase 2, Phase 3 7439-89-6, 15438-31-0 27284 23925
23
Vancomycin Approved Phase 3 1404-90-6 14969 441141
24 Tezosentan Investigational Phase 3 180384-57-0
25 Dermatologic Agents Phase 3,Phase 2
26 Emollients Phase 3
27 topoisomerase I inhibitors Phase 3
28 Topoisomerase Inhibitors Phase 3
29 Anti-Infective Agents Phase 3,Phase 2
30 Iron Chelating Agents Phase 2, Phase 3
31 Chelating Agents Phase 2, Phase 3
32 methicillin Phase 3
33 Anti-Bacterial Agents Phase 3
34
Titanium dioxide Approved Phase 2 13463-67-7
35
Ethanol Approved Phase 2 64-17-5 702
36 Radiation-Protective Agents Phase 2
37 Photosensitizing Agents Phase 2
38 Protective Agents Phase 2
39 Sunscreening Agents Phase 2
40 Anti-Infective Agents, Local Phase 2
41 Pharmaceutical Solutions Phase 2
42 Central Nervous System Depressants Phase 2,Phase 1
43
Oxycodone Approved, Illicit, Investigational Phase 1 76-42-6 5284603
44 Analgesics Phase 1
45 Analgesics, Opioid Phase 1
46 Narcotics Phase 1
47
Methimazole Approved 60-56-0 1349907
48
Propylthiouracil Approved, Investigational 51-52-5 657298
49
Propranolol Approved, Investigational 525-66-6 4946
50
Curcumin Approved, Experimental, Investigational 458-37-7 969516

Interventional clinical trials:

(show all 31)
# Name Status NCT ID Phase Drugs
1 Interventions for Children With Attention and Reading Disorders Completed NCT01133847 Phase 4 Methylphenidate;Mixed Salt Amphetamine;Atomoxetine;Guanfacine
2 Long-term Efficacy and Safety of V0034 CR 01B Cream in Patients With Moderate-to-severe Uremic Xerosis Completed NCT01084148 Phase 3 V0034CR01B;V0034CR01B vehicle
3 Efficacy, Local Tolerance and Patient Acceptability of a Moisturizing Emollient in Patients With Uremic Xerosis Completed NCT01084720 Phase 3 V0034 CR
4 Irinotecan Versus Only Best Supportive Care for Gastric Cancer Completed NCT00144378 Phase 3 Irinotecan
5 Conservative Iron Chelation as a Disease-modifying Strategy in Amyotrophic Lateral Sclerosis Recruiting NCT03293069 Phase 2, Phase 3 Deferiprone;Placebo Oral Tablet
6 A Study of AeroVanc for the Treatment of MRSA Infection in CF Patients Recruiting NCT03181932 Phase 3 Vancomycin inhalation powder;Placebo inhalation powder
7 A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension Enrolling by invitation NCT03683186 Phase 3 Ralinepag
8 Evaluation of the Protection Activity of Microfine Titanium Dioxide (Ti02), Pigmentary Ti02 and Bisoctrizole and Their Combinations in Voluntary Patients With Idiopathic Solar Urticaria (SU) Completed NCT00483496 Phase 2 Titanium dioxide (Ti02) microfine 12.15% alone (formula RV3131A-MV1209);Ti02 pigmentary 3% alone (formula RV3131A-MV1211);bisoctrizole 10% alone (formula RV3131A-MV1237);Ti02 microfine 12.15% + Ti02 pigmentary 3% (formula RV3131A-MV1213);Ti02 microfine 12.15% + bisoctrizole 10% (formula RV3131A-MV1329);Ti02 pigmentary 3% + bisoctrizole 10% (formula RV3131A-MV1212);Ti02 microfine 12.15% + Ti02 pigmentary 3% + bisoctrizole 10% [V0096 CR (formula RV3131A-MV1166)];V0096 CR vehicle (formula RV3131A-MV1197)
9 Systemic and Local Diffusion of Ethanol After Administration of Ethanol 96% Formulated in a Gel and Ethanol 98% Solution by the Percutaneous Route, in Patients With Congenital Venous Malformations:Pharmacokinetic, Pharmacodynamic and Clinical Study. Completed NCT00462462 Phase 2 Ethanol 96% Gel;Ethanol 98% Solution
10 Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients Completed NCT01160614 Phase 1 Oxycodone hydrochloride controlled-release (ORF) tablets
11 A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis Active, not recruiting NCT03626012 Phase 1 BIIB078;Placebo
12 The Epidemiology of Hepatitis E Virus Infection in Israel and Potential Risk Factors Unknown status NCT02419625 Not Applicable
13 Serum Betatrophin Levels and Its Influencing Factors in Patients With Hyperthyroidism Unknown status NCT02812888 thionamide treatment for 3 months
14 Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348672
15 Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye Unknown status NCT01348633
16 Assessment of Hepatitis B Virus Intra-host Population and Host-specific Immune Marker Diversity Unknown status NCT02148562
17 Understanding Clinical Phenotype and Collecting Biomarker Samples in C9ORF72 ALS Completed NCT02686268
18 Protocol TARC-ABPA Completed NCT01710930 Not Applicable
19 Clinical Evaluation of Patients With X-linked Retinitis Pigmentosa (XLRP) Recruiting NCT03314207
20 Predict to Prevent Frontotemporal Lobar Degeneration (FDT) and Amyotrophic Lateral Sclerosis (ALS) Recruiting NCT02590276 Not Applicable
21 Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects Recruiting NCT02372773
22 Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders Recruiting NCT01459302
23 TRIAL READY (Clinical Trial Readiness) Recruiting NCT03912987
24 OCT Angiography and NRAI in Dementia Recruiting NCT03761381
25 Study of Predictive Factors of Progression of Lateral Amyotrophic Sclerosis Recruiting NCT02360891
26 The Impact of Cranberries On the Microbiome and the Brain in Healthy Ageing sTudy (COMBAT) Recruiting NCT03679533 Not Applicable
27 Amyotrophic Lateral Sclerosis (ALS) Families Project Recruiting NCT03865420
28 The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study Recruiting NCT00317616
29 Cytokine Profile of Allergic Bronchopulmonary Aspergillosis Recruiting NCT03643185
30 Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation Active, not recruiting NCT01925196
31 Presymptomatic Neuromuscular Junction Defects and Compensatory Mechanisms in ALS Active, not recruiting NCT03573466 Not Applicable

Search NIH Clinical Center for Contagious Pustular Dermatitis

Cochrane evidence based reviews: ecthyma, contagious

Genetic Tests for Contagious Pustular Dermatitis

Anatomical Context for Contagious Pustular Dermatitis

The Foundational Model of Anatomy Ontology organs/tissues related to Contagious Pustular Dermatitis:

20
Skin

MalaCards organs/tissues related to Contagious Pustular Dermatitis:

42
Skin, Liver, Eye, Brain, Testes, T Cells

Publications for Contagious Pustular Dermatitis

Articles related to Contagious Pustular Dermatitis:

(show all 38)
# Title Authors Year
1
Pathogenicity of blood orf virus isolates in the development of dairy goat contagious pustular dermatitis. ( 29778194 )
2018
2
Isolation and molecular characterization of contagious pustular dermatitis virus from Rajasthan, India. ( 25674607 )
2014
3
Molecular and virological studies on contagious pustular dermatitis isolates from Egyptian sheep and goats. ( 20304450 )
2010
4
Orf: contagious pustular dermatitis. ( 20666089 )
2010
5
Orf (contagious pustular dermatitis) in farmworkers: prevalence and risk factors in three areas of England. ( 10452390 )
1999
6
Western blot analysis of virus-specific antibody responses for capripox and contagious pustular dermatitis viral infections in sheep. ( 7925674 )
1994
7
Molecular analysis of contagious pustular dermatitis virus: a simplified method for viral DNA extraction from scab material. ( 1816256 )
1991
8
Contagious pustular dermatitis (orf) infection in sheep and goats in Saudi Arabia. ( 1909477 )
1991
9
Detection of contagious pustular dermatitis virus of goats in a severe outbreak. ( 2588444 )
1989
10
Orf: contagious pustular dermatitis. ( 3179870 )
1988
11
Contagious pustular dermatitis (orf) of sheep affecting the ear following ear tagging. ( 3606509 )
1987
12
Contagious pustular dermatitis of sheep--possible confusion with vesicular diseases. ( 4004656 )
1985
13
Antigenic relationships among sheep pox, goat pox and contagious pustular dermatitis viruses. ( 6151351 )
1984
14
Prevalence of contagious pustular dermatitis (orf) in six million lambs at slaughter: a three-year study. ( 16030998 )
1983
15
Cross-neutralization tests on sheep pox, goat pox and contagious pustular dermatitis viruses. ( 90458 )
1979
16
Contagious pustular dermatitis of sheep in a veterinary student. ( 584593 )
1977
17
Cytopathogenicity of contagious pustular dermatitis virus in primary cell culture with special reference to the formation of intracytoplasmic inclusions. ( 4675558 )
1972
18
Propagation of contagious pustular dermatitis virus in HeLa cell cultures. ( 5169601 )
1971
19
The vaccination of young lambs against contagious pustular dermatitis. ( 5555757 )
1971
20
An outbreak of contagious pustular dermatitis associated with Dermatophilus congolensis infection. ( 5274960 )
1970
21
Possible "orf" (contagious pustular dermatitis, contagious ecthyma of sheep) infection in the dog. ( 5494712 )
1970
22
A case of orf (ecthyma contagiosum; contagious pustular dermatitis) contracted by a human from a wild Alaskan mountain goat. ( 4297665 )
1968
23
Growth of contagious pustular dermatitis virus in human tissue cultures. ( 14467780 )
1961
24
Studies with a strain of contagious pustular dermatitis virus in tissue culture. ( 14433531 )
1959
25
Contagious pustular dermatitis. IV. Immunological reactions. ( 13502481 )
1958
26
The immunological relations of the contagious pustular dermatitis virus to the mammalian pox group. ( 13596274 )
1958
27
Contagious pustular dermatitis virus. I. Studies on morphology. ( 13416415 )
1957
28
Human infections with the virus of ovine contagious pustular dermatitis (scabby mouth). ( 13430966 )
1957
29
Contagious pustular dermatitis. II. Pathological histology. ( 13449179 )
1957
30
Contagious pustular dermatitis. III. Experimental infection. ( 13481166 )
1957
31
Orf: contagious pustular dermatitis of sheep. ( 13361058 )
1956
32
Human infection with the virus of contagious pustular dermatitis. ( 14814843 )
1951
33
Complement-fixation tests in the diagnosis of contagious pustular dermatitis infection in man. ( 14898387 )
1951
34
The immunological relationship between a new virus, proliferative dermatitis of the legs (strawberry foot rot) of sheep, and the viruses of vaccinia and contagious pustular dermatitis. ( 18099893 )
1948
35
A case of orf; contagious pustular dermatitis; identification of the virus. ( 18123062 )
1948
36
The immunological relationships of strains of contagious pustular dermatitis virus. ( 20293732 )
1947
37
The relationship between the virus of contagious pustular dermatitis and a virus isolated from sheep papillomatosis by Selbie. ( 20293733 )
1947
38
Infection of man by the virus of contagious pustular dermatitis of sheep. ( 20279048 )
1946

Variations for Contagious Pustular Dermatitis

Expression for Contagious Pustular Dermatitis

Search GEO for disease gene expression data for Contagious Pustular Dermatitis.

Pathways for Contagious Pustular Dermatitis

Pathways related to Contagious Pustular Dermatitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.52 CYC1 MT-CYB

GO Terms for Contagious Pustular Dermatitis

Cellular components related to Contagious Pustular Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 respiratory chain GO:0070469 8.96 CYC1 MT-CYB
2 mitochondrial respiratory chain complex III GO:0005750 8.62 CYC1 MT-CYB

Biological processes related to Contagious Pustular Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.33 AKR7A2 CYC1 MT-CYB
2 mitochondrial electron transport, ubiquinol to cytochrome c GO:0006122 8.96 CYC1 MT-CYB
3 response to glucagon GO:0033762 8.62 CYC1 MT-CYB

Molecular functions related to Contagious Pustular Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 electron transfer activity GO:0009055 8.8 AKR7A2 CYC1 MT-CYB

Sources for Contagious Pustular Dermatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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