MCID: CNV007
MIFTS: 20

Conventional Central Osteosarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Conventional Central Osteosarcoma

MalaCards integrated aliases for Conventional Central Osteosarcoma:

Name: Conventional Central Osteosarcoma 12 15
Intracortical Osteosarcoma 71
Conventional Osteosarcoma 12
Medullary Osteosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3378
UMLS 71 C1266166

Summaries for Conventional Central Osteosarcoma

MalaCards based summary : Conventional Central Osteosarcoma, also known as intracortical osteosarcoma, is related to malignant mesenchymoma and spindle cell sarcoma, and has symptoms including pain An important gene associated with Conventional Central Osteosarcoma is MIR539 (MicroRNA 539). Affiliated tissues include bone.

Related Diseases for Conventional Central Osteosarcoma

Diseases related to Conventional Central Osteosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 malignant mesenchymoma 30.2 SERPINA3 MDM2
2 spindle cell sarcoma 30.0 SERPINA3 MDM2 CCNB3
3 extraosseous osteosarcoma 29.5 MDM2 CDK4
4 liposarcoma 29.4 MDM2 EWSR1 CDK4
5 pleomorphic liposarcoma 29.2 SERPINA3 MDM2 EWSR1 CDK4
6 bone sarcoma 28.9 SERPINA3 MIR133A1 MDM2 EWSR1 CD99 CCNB3
7 childhood intracortical osteosarcoma 11.5
8 extraskeletal chondroma 10.5 SERPINA3 EWSR1
9 intracranial primitive neuroectodermal tumor 10.5 EWSR1 CD99
10 extraskeletal mesenchymal chondrosarcoma 10.5 EWSR1 CD99
11 osteogenic sarcoma 10.5
12 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.5 EWSR1 CD99
13 ewing sarcoma of bone 10.5 EWSR1 CD99
14 lung sarcoma 10.5 SERPINA3 EWSR1
15 sarcomatosis 10.5 EWSR1 CREB3L1
16 central nervous system mesenchymal non-meningothelial tumor 10.5 EWSR1 CD99
17 proliferative fasciitis 10.5 USP6 SERPINA3
18 extraskeletal ewing sarcoma 10.4 EWSR1 CD99
19 extraosseous ewing sarcoma 10.4 EWSR1 CD99
20 olfactory nerve neoplasm 10.4 EWSR1 CD99
21 cranial nerve malignant neoplasm 10.4 EWSR1 CD99
22 soft tissue sarcoma 10.4 MDM2 EWSR1
23 cranial nerve neoplasm 10.3 EWSR1 CD99
24 congenital fibrosarcoma 10.3 SERPINA3 EWSR1 CCNB3
25 tenosynovial giant cell tumor 10.3 USP6 SERPINA3
26 askin's tumor 10.3 EWSR1 CD99 CCNB3
27 cellular congenital mesoblastic nephroma 10.3 CCNB3 BCOR
28 hemangiopericytoma, malignant 10.2 SERPINA3 MDM2 CD99
29 ossifying fibroma 10.2 USP6 SERPINA3 MDM2
30 ossifying fibromyxoid tumor 10.2 CCNB3 BCOR
31 clear cell sarcoma 10.2 EWSR1 CCNB3 BCOR
32 periosteal osteogenic sarcoma 10.2 SATB2 MDM2 EWSR1
33 small cell sarcoma 10.2 EWSR1 CCNB3 BCOR
34 giant cell reparative granuloma 10.2 USP6 SERPINA3
35 kidney rhabdoid cancer 10.2 EWSR1 CCNB3 BCOR
36 endometrial stromal tumor 10.2 EWSR1 CCNB3 BCOR
37 heart cancer 10.1 SERPINA3 MDM2
38 kidney cortex disease 10.1 CCNB3 BCOR
39 fibrosarcomatous osteosarcoma 10.1 SERPINA3 FAM180A
40 sweat gland benign neoplasm 10.1 SERPINA3 EWSR1
41 chondroblastic osteosarcoma 10.1 SERPINA3 FAM180A
42 telangiectatic osteogenic sarcoma 10.1 USP6 MDM2 COPS3
43 autonomic nervous system neoplasm 10.1 SERPINA3 MDM2 EWSR1
44 peripheral nervous system neoplasm 10.0 SERPINA3 MDM2 EWSR1
45 pediatric fibrosarcoma 10.0 SERPINA3 EWSR1 CCNB3 BCOR
46 mesenchymal cell neoplasm 10.0 SERPINA3 EWSR1 CCNB3 BCOR
47 chondrosarcoma, extraskeletal myxoid 10.0 EWSR1 CD99 CCNB3 BCOR
48 kidney sarcoma 10.0 SATB2 EWSR1 CCNB3 BCOR
49 ring chromosome 7 9.9 MDM2 CDK4
50 mediastinum liposarcoma 9.9 MDM2 CDK4

Graphical network of the top 20 diseases related to Conventional Central Osteosarcoma:



Diseases related to Conventional Central Osteosarcoma

Symptoms & Phenotypes for Conventional Central Osteosarcoma

UMLS symptoms related to Conventional Central Osteosarcoma:


pain

Drugs & Therapeutics for Conventional Central Osteosarcoma

Search Clinical Trials , NIH Clinical Center for Conventional Central Osteosarcoma

Genetic Tests for Conventional Central Osteosarcoma

Anatomical Context for Conventional Central Osteosarcoma

MalaCards organs/tissues related to Conventional Central Osteosarcoma:

40
Bone

Publications for Conventional Central Osteosarcoma

Articles related to Conventional Central Osteosarcoma:

# Title Authors PMID Year
1
The association between the computed tomography findings, histologic features, and outcome of osteosarcoma of the jaw. 61
15742279 2005
2
Outcome of radiation-related osteosarcoma after treatment of childhood and adolescent cancer: a study of 23 cases. 61
10561354 1999
3
Chondroblastic osteosarcoma: characterisation by gadolinium-enhanced MR imaging correlated with histopathology. 61
9554005 1998
4
[Comparative genomic hybridization (CGH) for detecting a heretofore undescribed amplified chromosomal segment in high-grade medullary osteosarcoma]. 61
10095431 1998
5
Intracortical low grade osteosarcoma. A unique case and review of the literature on intracortical osteosarcoma. 61
8705794 1996
6
Juxtacortical osteosarcoma: a radiologic and histologic spectrum. 61
3860961 1985
7
Survival after metastasis in osteosarcoma. 61
6946292 1981

Variations for Conventional Central Osteosarcoma

Expression for Conventional Central Osteosarcoma

Search GEO for disease gene expression data for Conventional Central Osteosarcoma.

Pathways for Conventional Central Osteosarcoma

GO Terms for Conventional Central Osteosarcoma

Biological processes related to Conventional Central Osteosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell cycle arrest GO:0071157 8.62 MDM2 CDK4

Sources for Conventional Central Osteosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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