MCID: CNV007
MIFTS: 27

Conventional Central Osteosarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Conventional Central Osteosarcoma

MalaCards integrated aliases for Conventional Central Osteosarcoma:

Name: Conventional Central Osteosarcoma 12 15
Intracortical Osteosarcoma 74
Conventional Osteosarcoma 12
Medullary Osteosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3378
UMLS 74 C1266166

Summaries for Conventional Central Osteosarcoma

MalaCards based summary : Conventional Central Osteosarcoma, also known as intracortical osteosarcoma, is related to extraosseous osteosarcoma and liposarcoma, and has symptoms including pain An important gene associated with Conventional Central Osteosarcoma is BCOR (BCL6 Corepressor), and among its related pathways/superpathways are Glucocorticoid receptor regulatory network and Regulation of retinoblastoma protein. Affiliated tissues include bone, skin and kidney.

Related Diseases for Conventional Central Osteosarcoma

Diseases related to Conventional Central Osteosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 extraosseous osteosarcoma 29.8 MDM2 SPARC
2 liposarcoma 29.7 EWSR1 MDM2
3 malignant mesenchymoma 29.6 EWSR1 MDM2
4 childhood intracortical osteosarcoma 11.3
5 osteogenic sarcoma 10.3
6 retroperitoneal sarcoma 10.2 BCOR MDM2
7 kidney clear cell sarcoma 10.2 BCOR SATB2
8 small cell sarcoma 10.1 BCOR MDM2
9 juxtacortical osteosarcoma 10.1 MDM2 SATB2
10 malignant fibrous histiocytoma of bone 10.1 BGLAP MDM2
11 rhabdoid cancer 10.1 BCOR EWSR1
12 clear cell sarcoma 10.1 BCOR EWSR1
13 papillary cystadenocarcinoma 10.1 BGLAP SPARC
14 cellular myxoid liposarcoma 10.0 EWSR1 MDM2
15 myxoid liposarcoma 10.0 EWSR1 MDM2
16 histiocytoma 10.0 EWSR1 MDM2
17 fibrosarcomatous osteosarcoma 10.0 BGLAP SPARC
18 osseous heteroplasia, progressive 10.0 BGLAP SPARC
19 soft tissue sarcoma 10.0 EWSR1 MDM2
20 osteofibrous dysplasia 10.0 BGLAP SPARC
21 fibrous dysplasia 10.0 BGLAP SPARC
22 chondroblastoma 9.9
23 muscle cancer 9.9 EWSR1 MDM2
24 connective tissue cancer 9.9 EWSR1 MDM2
25 brittle bone disorder 9.9 BGLAP SPARC
26 small cell osteogenic sarcoma 9.9 BCOR EWSR1 SATB2
27 peripheral osteosarcoma 9.9 MDM2 SATB2 SPARC
28 osteoblastoma 9.8
29 sarcoma 9.8
30 mesenchymoma 9.8
31 skin sarcoma 9.8
32 pleomorphic liposarcoma 9.8
33 rhabdomyosarcoma 2 9.8 EWSR1 MDM2
34 nervous system cancer 9.7 EWSR1 MDM2
35 osteoporosis 9.6 BGLAP SATB2 SPARC
36 periosteal osteogenic sarcoma 9.6 BGLAP MDM2 SATB2 SPARC
37 bone osteosarcoma 9.2 BCOR BGLAP MAP7D3 MDM2 SATB2 SPARC

Graphical network of the top 20 diseases related to Conventional Central Osteosarcoma:



Diseases related to Conventional Central Osteosarcoma

Symptoms & Phenotypes for Conventional Central Osteosarcoma

UMLS symptoms related to Conventional Central Osteosarcoma:


pain

Drugs & Therapeutics for Conventional Central Osteosarcoma

Search Clinical Trials , NIH Clinical Center for Conventional Central Osteosarcoma

Genetic Tests for Conventional Central Osteosarcoma

Anatomical Context for Conventional Central Osteosarcoma

MalaCards organs/tissues related to Conventional Central Osteosarcoma:

42
Bone, Skin, Kidney

Publications for Conventional Central Osteosarcoma

Articles related to Conventional Central Osteosarcoma:

(show all 13)
# Title Authors Year
1
Intracortical osteosarcoma of the tibia in a 14-year-old girl. ( 21304410 )
2011
2
Intracortical osteosarcoma; two-year delay in diagnosis. ( 12324829 )
2002
3
Intracortical osteosarcoma: is MRI useful? ( 11588687 )
2001
4
Intracortical osteosarcoma: report of a case. ( 11000737 )
2000
5
Unusual evolution of a benign-looking cortical defect of the proximal humerus. A case of intracortical osteosarcoma? ( 9586258 )
1998
6
Intracortical osteosarcoma. ( 9592909 )
1998
7
Intracortical low grade osteosarcoma. A unique case and review of the literature on intracortical osteosarcoma. ( 8705794 )
1996
8
Case report 700: Primary intracortical osteosarcoma of femur, sclerosing variant, grade 1 to 2 anaplasia. ( 1776030 )
1991
9
Intracortical osteosarcoma. A case report. ( 2060212 )
1991
10
Case report 585: Intracortical osteosarcoma of tibia. ( 2692187 )
1989
11
Intracortical osteosarcoma. ( 6582789 )
1984
12
Intracortical osteosarcoma: rare entity or early manifestation of classical osteosarcoma? ( 6575445 )
1983
13
Intracortical osteosarcoma. ( 7002283 )
1980

Variations for Conventional Central Osteosarcoma

Expression for Conventional Central Osteosarcoma

Search GEO for disease gene expression data for Conventional Central Osteosarcoma.

Pathways for Conventional Central Osteosarcoma

Pathways related to Conventional Central Osteosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.87 BGLAP MDM2
2 10.37 BGLAP MDM2

GO Terms for Conventional Central Osteosarcoma

Biological processes related to Conventional Central Osteosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ossification GO:0001503 9.48 BGLAP SPARC
2 response to glucocorticoid GO:0051384 9.46 BGLAP SPARC
3 roof of mouth development GO:0060021 9.43 BCOR SATB2
4 heart development GO:0007507 9.43 BCOR MDM2 SPARC
5 bone development GO:0060348 9.4 BGLAP SPARC
6 cellular response to organic substance GO:0071310 9.37 MDM2 SATB2
7 odontogenesis GO:0042476 9.32 BCOR BGLAP
8 osteoblast development GO:0002076 9.16 BGLAP SATB2
9 response to gravity GO:0009629 8.96 BGLAP SPARC
10 cellular response to growth factor stimulus GO:0071363 8.8 BGLAP MDM2 SPARC

Sources for Conventional Central Osteosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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