MCID: CNV007
MIFTS: 27

Conventional Central Osteosarcoma

Categories: Bone diseases, Cancer diseases

Aliases & Classifications for Conventional Central Osteosarcoma

MalaCards integrated aliases for Conventional Central Osteosarcoma:

Name: Conventional Central Osteosarcoma 12 15
Intracortical Osteosarcoma 73
Conventional Osteosarcoma 12
Medullary Osteosarcoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3378
UMLS 73 C1266166

Summaries for Conventional Central Osteosarcoma

MalaCards based summary : Conventional Central Osteosarcoma, also known as intracortical osteosarcoma, is related to extraosseous osteosarcoma and liposarcoma, and has symptoms including pain An important gene associated with Conventional Central Osteosarcoma is BCOR (BCL6 Corepressor), and among its related pathways/superpathways are Glucocorticoid receptor regulatory network and Regulation of retinoblastoma protein. Affiliated tissues include bone and kidney.

Related Diseases for Conventional Central Osteosarcoma

Diseases related to Conventional Central Osteosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 extraosseous osteosarcoma 29.8 MDM2 SPARC
2 liposarcoma 29.8 EWSR1 MDM2
3 malignant mesenchymoma 29.7 EWSR1 MDM2
4 childhood intracortical osteosarcoma 11.3
5 retroperitoneal sarcoma 10.1 BCOR MDM2
6 small cell sarcoma 10.1 BCOR MDM2
7 rhabdoid cancer 10.1 BCOR EWSR1
8 clear cell sarcoma 10.1 BCOR EWSR1
9 cellular myxoid liposarcoma 10.1 EWSR1 MDM2
10 myxoid liposarcoma 10.1 EWSR1 MDM2
11 malignant fibrous histiocytoma of bone 10.1 BGLAP MDM2
12 histiocytoma 10.1 EWSR1 MDM2
13 papillary cystadenocarcinoma 10.1 BGLAP SPARC
14 soft tissue sarcoma 10.0 EWSR1 MDM2
15 kidney clear cell sarcoma 10.0 BCOR SATB2
16 fibrosarcomatous osteosarcoma 10.0 BGLAP SPARC
17 osseous heteroplasia, progressive 10.0 BGLAP SPARC
18 osteogenic sarcoma 10.0
19 osteofibrous dysplasia 10.0 BGLAP SPARC
20 fibrous dysplasia 10.0 BGLAP SPARC
21 muscle cancer 10.0 EWSR1 MDM2
22 juxtacortical osteosarcoma 10.0 MDM2 SATB2
23 connective tissue cancer 10.0 EWSR1 MDM2
24 brittle bone disorder 10.0 BGLAP SPARC
25 rhabdomyosarcoma 2 9.9 EWSR1 MDM2
26 chondroblastoma 9.9
27 nervous system cancer 9.9 EWSR1 MDM2
28 small cell osteogenic sarcoma 9.9 BCOR EWSR1 SATB2
29 peripheral osteosarcoma 9.9 MDM2 SATB2 SPARC
30 sarcoma 9.8
31 mesenchymoma 9.8
32 pleomorphic liposarcoma 9.8
33 periosteal osteogenic sarcoma 9.7 BGLAP MDM2 SATB2 SPARC
34 osteoporosis 9.6 BGLAP SATB2 SPARC
35 bone osteosarcoma 9.4 BCOR BGLAP MAP7D3 MDM2 SATB2 SPARC

Graphical network of the top 20 diseases related to Conventional Central Osteosarcoma:



Diseases related to Conventional Central Osteosarcoma

Symptoms & Phenotypes for Conventional Central Osteosarcoma

UMLS symptoms related to Conventional Central Osteosarcoma:


pain

Drugs & Therapeutics for Conventional Central Osteosarcoma

Search Clinical Trials , NIH Clinical Center for Conventional Central Osteosarcoma

Genetic Tests for Conventional Central Osteosarcoma

Anatomical Context for Conventional Central Osteosarcoma

MalaCards organs/tissues related to Conventional Central Osteosarcoma:

41
Bone, Kidney

Publications for Conventional Central Osteosarcoma

Articles related to Conventional Central Osteosarcoma:

(show all 13)
# Title Authors Year
1
Intracortical osteosarcoma of the tibia in a 14-year-old girl. ( 21304410 )
2011
2
Intracortical osteosarcoma; two-year delay in diagnosis. ( 12324829 )
2002
3
Intracortical osteosarcoma: is MRI useful? ( 11588687 )
2001
4
Intracortical osteosarcoma: report of a case. ( 11000737 )
2000
5
Unusual evolution of a benign-looking cortical defect of the proximal humerus. A case of intracortical osteosarcoma? ( 9586258 )
1998
6
Intracortical osteosarcoma. ( 9592909 )
1998
7
Intracortical low grade osteosarcoma. A unique case and review of the literature on intracortical osteosarcoma. ( 8705794 )
1996
8
Case report 700: Primary intracortical osteosarcoma of femur, sclerosing variant, grade 1 to 2 anaplasia. ( 1776030 )
1991
9
Intracortical osteosarcoma. A case report. ( 2060212 )
1991
10
Case report 585: Intracortical osteosarcoma of tibia. ( 2692187 )
1989
11
Intracortical osteosarcoma. ( 6582789 )
1984
12
Intracortical osteosarcoma: rare entity or early manifestation of classical osteosarcoma? ( 6575445 )
1983
13
Intracortical osteosarcoma. ( 7002283 )
1980

Variations for Conventional Central Osteosarcoma

Expression for Conventional Central Osteosarcoma

Search GEO for disease gene expression data for Conventional Central Osteosarcoma.

Pathways for Conventional Central Osteosarcoma

Pathways related to Conventional Central Osteosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.87 BGLAP MDM2
2 10.37 BGLAP MDM2

GO Terms for Conventional Central Osteosarcoma

Biological processes related to Conventional Central Osteosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ossification GO:0001503 9.48 BGLAP SPARC
2 response to glucocorticoid GO:0051384 9.46 BGLAP SPARC
3 roof of mouth development GO:0060021 9.43 BCOR SATB2
4 heart development GO:0007507 9.43 BCOR MDM2 SPARC
5 bone development GO:0060348 9.4 BGLAP SPARC
6 cellular response to organic substance GO:0071310 9.37 MDM2 SATB2
7 odontogenesis GO:0042476 9.32 BCOR BGLAP
8 osteoblast development GO:0002076 9.16 BGLAP SATB2
9 response to gravity GO:0009629 8.96 BGLAP SPARC
10 cellular response to growth factor stimulus GO:0071363 8.8 BGLAP MDM2 SPARC

Sources for Conventional Central Osteosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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