MCID: CRN021
MIFTS: 28

Cornea Cancer

Categories: Cancer diseases, Eye diseases, Neuronal diseases

Aliases & Classifications for Cornea Cancer

MalaCards integrated aliases for Cornea Cancer:

Name: Cornea Cancer 12 15
Malignant Neoplasm of Cornea 12 74
Neoplasm of Cornea 12 74
Malignant Tumor of Cornea 12
Malignant Corneal Tumor 12
Corneal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6199
ICD9CM 36 190.4
NCIt 51 C3565 C4361
SNOMED-CT 69 93766000
ICD10 34 C69.1

Summaries for Cornea Cancer

MalaCards based summary : Cornea Cancer, also known as malignant neoplasm of cornea, is related to cerebral convexity meningioma and intraventricular meningioma. An important gene associated with Cornea Cancer is NF2 (Neurofibromin 2), and among its related pathways/superpathways are Neural Crest Differentiation and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include eye and brain, and related phenotypes are behavior/neurological and vision/eye

Related Diseases for Cornea Cancer

Graphical network of the top 20 diseases related to Cornea Cancer:



Diseases related to Cornea Cancer

Symptoms & Phenotypes for Cornea Cancer

MGI Mouse Phenotypes related to Cornea Cancer:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.35 FGF2 GFAP HDGF NF2 PLAU
2 vision/eye MP:0005391 8.92 FGF2 GFAP NF2 PLAU

Drugs & Therapeutics for Cornea Cancer

Search Clinical Trials , NIH Clinical Center for Cornea Cancer

Genetic Tests for Cornea Cancer

Anatomical Context for Cornea Cancer

MalaCards organs/tissues related to Cornea Cancer:

42
Eye, Brain

Publications for Cornea Cancer

Articles related to Cornea Cancer:

# Title Authors Year
1
Choroidal Lymphoma Discovered on Ultrasound in a Patient with Suspected Corneal Tumor. ( 30320105 )
2018
2
LEOPARD syndrome with a new association of congenital corneal tumor, choristoma. ( 12657016 )
2003

Variations for Cornea Cancer

Expression for Cornea Cancer

Search GEO for disease gene expression data for Cornea Cancer.

Pathways for Cornea Cancer

Pathways related to Cornea Cancer according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.38 FGF2 GFAP
2 11.15 FGF2 GFAP
3 10.97 FGF2 PLAU
4 10.76 FGF2 PLAU
5 10.4 FGF2 GFAP HDGF
6 10.31 FGF2 PLAU

GO Terms for Cornea Cancer

Cellular components related to Cornea Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.26 AZU1 FGF2 HDGF PLAU
2 cell body GO:0044297 8.62 GFAP NF2

Biological processes related to Cornea Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.13 FGF2 HDGF PLAU
2 chemotaxis GO:0006935 8.8 AZU1 FGF2 PLAU

Molecular functions related to Cornea Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 8.8 AZU1 FGF2 HDGF
2 integrin binding GO:0005178 8.65 FGF2

Sources for Cornea Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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