MCID: CRN004
MIFTS: 26

Corneal Abscess

Categories: Eye diseases

Aliases & Classifications for Corneal Abscess

MalaCards integrated aliases for Corneal Abscess:

Name: Corneal Abscess 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11543
ICD9CM 34 370.55
NCIt 49 C26969
SNOMED-CT 67 64366002
ICD10 32 H16.31
UMLS 71 C0155091

Summaries for Corneal Abscess

MalaCards based summary : Corneal Abscess is related to psoriasis and deep keratitis. An important gene associated with Corneal Abscess is HRK (Harakiri, BCL2 Interacting Protein), and among its related pathways/superpathways are Defensins and Staphylococcus aureus infection. Affiliated tissues include eye, testes and endothelial, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Corneal Abscess

Diseases related to Corneal Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
# Related Disease Score Top Affiliating Genes
1 psoriasis 28.8 SLPI PI3 DEFB4A
2 deep keratitis 10.2 IL4I1 HRK
3 keratitis, hereditary 10.2
4 keratopathy 9.9
5 pustulosis of palm and sole 9.9
6 endophthalmitis 9.9
7 conjunctivitis 9.9
8 candidiasis 9.9 DEFB4A DEFB1
9 vaginitis 9.9 SLPI DEFB4A
10 osteonecrosis of the jaw 9.9 DEFB4A DEFB1
11 vaginal disease 9.8 SLPI DEFB4A
12 vulvovaginal candidiasis 9.8 DEFB4A DEFB1
13 aggressive periodontitis 9.8 DEFB4A DEFB1
14 pustular psoriasis 9.8 SLPI PI3
15 intraocular pressure quantitative trait locus 9.8
16 hypopyon 9.8
17 chlamydia 9.8
18 punctate epithelial keratoconjunctivitis 9.8
19 urethritis 9.8
20 iritis 9.8
21 rhinitis 9.8
22 atrophic rhinitis 9.8
23 cataract 9.8
24 corneal ulcer 9.8
25 impetigo 9.8
26 ophthalmia neonatorum 9.8
27 bacterial conjunctivitis 9.8
28 48,xyyy 9.8
29 fungal keratitis 9.8
30 periodontitis 9.8 DEFB4A DEFB1
31 farmer's lung 9.7 SLPI PI3
32 pasteurellosis 9.7 SLPI PI3
33 neurofibromatosis, type ii 9.7 DEFB4A DEFB1
34 salmonellosis 9.7 DEFB4A DEFB1
35 gingivitis 9.7 SLPI DEFB4A
36 peptic ulcer disease 9.5 DEFB4A DEFB1
37 oral candidiasis 9.5 SLPI DEFB4A DEFB1
38 bacterial vaginosis 9.5 PI3 DEFB4A
39 bacterial pneumonia 9.4 SLPI DEFB4A
40 pulmonary disease, chronic obstructive 9.3 SLPI PI3 DEFB1
41 bacterial infectious disease 9.2 PI3 DEFB4A DEFB1
42 cystic fibrosis 8.9 SLPI PI3 DEFB4A DEFB1

Graphical network of the top 20 diseases related to Corneal Abscess:



Diseases related to Corneal Abscess

Symptoms & Phenotypes for Corneal Abscess

GenomeRNAi Phenotypes related to Corneal Abscess according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.28 NID1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.28 HRK
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.28 HRK
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.28 NID1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-181 9.28 HRK
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-38 9.28 HRK NID1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.28 NID1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.28 NID1

Drugs & Therapeutics for Corneal Abscess

Search Clinical Trials , NIH Clinical Center for Corneal Abscess

Genetic Tests for Corneal Abscess

Anatomical Context for Corneal Abscess

MalaCards organs/tissues related to Corneal Abscess:

40
Eye, Testes, Endothelial

Publications for Corneal Abscess

Articles related to Corneal Abscess:

(show top 50) (show all 129)
# Title Authors PMID Year
1
Microbiologic profile of the mycosic absess on a reference center in Tunisia. 61
31729735 2019
2
Polymicrobial Keratitis With Cryptococcus curvatus, Candida parapsilosis, and Stenotrophomonas maltophilia After Penetrating Keratoplasty: A Rare Case Report With Literature Review. 61
29944507 2019
3
Listeria monocytogenes and ocular abscess: an atypical but yet potential association. 61
29086326 2018
4
Corneal abscess due to Moraxella nonliquefaciens. 61
30128157 2018
5
Non-typeable Streptococcus pneumoniae infection in a medical center in Taiwan after wide use of pneumococcal conjugate vaccine. 61
29804657 2018
6
Results of therapeutic penetrating keratoplasty for bacterial and fungal keratitis. 61
27723008 2017
7
Surgical treatment of Metarhizium anisopliae sclerokeratitis and endophthalmitis. 61
28643721 2017
8
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions. 61
28516471 2017
9
Intracorneal Amphotericin B Injection in a Case of Indolent Candidal Keratitis. 61
28658821 2017
10
Lacrimal gland ductal carcinomas: Clinical, Morphological and Genetic characterization and implications for targeted treatment. 61
27808478 2017
11
360 Degree Deep Corneal Vascularization In A Case Of Endophthalmitis With Corneal Abscess. 61
28718272 2017
12
Corneal Cross-Linking as a Treatment for Fungal Keratitis Associated with Corneal Melting. 61
28611646 2017
13
Fusarium dimerum Species Complex (Fusarium penzigii) Keratitis After Corneal Trauma. 61
27631818 2016
14
Multiorganism, drug-resistant keratitis treated by corneal crosslinking. 61
26833230 2016
15
[Prolonged topical natamycin 5‚ÄČ% therapy before and after keratoplasty for Fusarium keratitis]. 61
26205744 2016
16
Post-traumatic endophthalmitis in 143 eyes of children and adolescents from India. 61
26869162 2016
17
First reported case of a corneal abscess caused by Massilia timonae. 61
26279207 2016
18
Ocular complications in children after hematopoietic stem cell transplantation without total body irradiation. 61
25708560 2015
19
Multidrug resistant Fusarium keratitis. 61
25443198 2015
20
Alternaria is an Infrequent Cause of Keratitis: A Case Report and Review of the Literature. 61
25794328 2015
21
[Non-traumatic corneal perforations: Therapeutic modalities]. 61
25891769 2015
22
Severe microbial keratitis and associated perforation after corneal crosslinking for keratoconus. 61
25435381 2015
23
Infectious crystalline keratopathy caused by Pseudomonas fluorescens. 61
24113463 2015
24
Severe Staphylococcus lugdunensis keratitis. 61
25082203 2015
25
[THE FIRST CASE OF OCULAR THELAZIASIS IN CROATIA]. 61
29087095 2015
26
Corneal Infection Therapy with Topical Bacteriophage Administration. 61
26862360 2015
27
Femtosecond Laser-Assisted Intra-Corneal Drug Delivery. 61
24506334 2015
28
Keratitis after corneal projection of biological fluids: a possible occupational prejudice? 61
25291778 2014
29
Topical voriconazole therapy of Purpureocillium lilacinum keratitis that occurred in disposable soft contact lens wearers. 61
24974133 2014
30
Histopathological Studies on Rabbits Infected by Bacteria Causing Infectious Keratitis in Human through Eye Inoculation. 61
25505861 2014
31
Fungal keratitis secondary to Scedosporium apiospermum infection and successful treatment with surgical and medical intervention. 61
23612853 2014
32
Alternaria keratitis and hypopyon after clear-cornea phacoemulsification. 61
24461506 2014
33
[Corneal abscess: serious complication of neglected and poorly managed corneal trauma]. 61
25821547 2014
34
Preparation and characterization of a hydrogel carrier to deliver gatifloxacin and its application as a therapeutic contact lens for bacterial keratitis therapy. 61
24057809 2013
35
Rehabilitation of an Infected Eye with an Acrylic Ball Implant and a Custom made Scleral Ocular Prosthesis. 61
24431757 2013
36
Long-term follow-up after successful treatment of Pythium insidiosum keratitis in Israel. 61
23627654 2013
37
Loss of sight caused by calcium hydroxide paste accidentally splashed into the eye during endodontic treatment: case report. 61
24195193 2013
38
Rapid diagnosis of acanthamoeba keratitis using non-nutrient agar with a lawn of E. coli. 61
23514313 2013
39
Acanthamoeba T4 genotype associated with keratitis infections in Tunisia. 61
23052779 2013
40
Bacillus cereus infection after Descemet stripping endothelial keratoplasty. 61
22262217 2012
41
Loss of sight caused by calcium hydroxide paste accidentally splashed into the eye during endodontic treatment: case report. 61
22673219 2012
42
Pseudomonas keratitis 4 years after laser in situ keratomileusis. 61
21666521 2011
43
[Severe keratomycosis due to Fusarium solani induced by a telluric foreign body: About a case in moroccan Sahara]. 61
24451564 2011
44
Corneal abscess caused by Bipolaris spicifera. 61
21623109 2011
45
Unusual presentation of phacolytic glaucoma: simulating microbial keratitis. 61
22606478 2011
46
Efficacy and safety of short-duration topical treatment with azithromycin oil-based eyedrops in an experimental model of corneal refractive surgery. 61
20544676 2010
47
Severe keratopathy in patients with AIDS with undiagnosed lagophthalmos. 61
20628297 2010
48
Successful treatment of Pseudallescheria boydii keratitis with topical natamycin as monotherapy. 61
20925580 2010
49
Over-Treated Corneal Abscess May Be Toxic Keratopathy. 61
20737055 2010
50
Atypical mycobacterium keratitis associated with penetrating keratoplasty: case report of successful therapy with topical gatifloxacin 0.3%. 61
20164758 2010

Variations for Corneal Abscess

Expression for Corneal Abscess

Search GEO for disease gene expression data for Corneal Abscess.

Pathways for Corneal Abscess

Pathways related to Corneal Abscess according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.13 PI3 DEFB4A DEFB1
2 10.94 DEFB4A DEFB1

GO Terms for Corneal Abscess

Cellular components related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.1 SLPI PI3 NID1 IL4I1 DEFB4A DEFB1
2 Golgi lumen GO:0005796 8.96 DEFB4A DEFB1

Biological processes related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.54 SLPI DEFB4A DEFB1
2 negative regulation of peptidase activity GO:0010466 9.43 SLPI PI3
3 defense response to Gram-positive bacterium GO:0050830 9.4 DEFB4A DEFB1
4 defense response to bacterium GO:0042742 9.33 SLPI DEFB4A DEFB1
5 defense response to Gram-negative bacterium GO:0050829 9.32 DEFB4A DEFB1
6 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.26 DEFB4A DEFB1
7 antibacterial humoral response GO:0019731 8.96 SLPI DEFB1
8 antimicrobial humoral response GO:0019730 8.8 PI3 DEFB4A DEFB1

Molecular functions related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 9.26 SLPI PI3
2 serine-type endopeptidase inhibitor activity GO:0004867 9.16 SLPI PI3
3 endopeptidase inhibitor activity GO:0004866 8.96 SLPI PI3
4 CCR6 chemokine receptor binding GO:0031731 8.62 DEFB4A DEFB1

Sources for Corneal Abscess

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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