MCID: CRN004
MIFTS: 29

Corneal Abscess

Categories: Eye diseases

Aliases & Classifications for Corneal Abscess

MalaCards integrated aliases for Corneal Abscess:

Name: Corneal Abscess 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11543
ICD9CM 36 370.55
NCIt 51 C26969
SNOMED-CT 69 64366002
ICD10 34 H16.31
UMLS 74 C0155091

Summaries for Corneal Abscess

MalaCards based summary : Corneal Abscess is related to endophthalmitis and osteonecrosis of the jaw. An important gene associated with Corneal Abscess is DEFB1 (Defensin Beta 1), and among its related pathways/superpathways is Integrated Breast Cancer Pathway. The drugs Formaldehyde and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include breast, eye and lung, and related phenotype is neoplasm.

Related Diseases for Corneal Abscess

Diseases related to Corneal Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 99)
# Related Disease Score Top Affiliating Genes
1 endophthalmitis 30.3 DEFB1 PLG
2 osteonecrosis of the jaw 10.4 DEFB1 DEFB4A
3 vulvovaginal candidiasis 10.3 DEFB1 DEFB4A
4 vulvar sarcoma 10.3 AR KRT7
5 erysipeloid 10.3 PLG RAD51
6 vaginitis 10.3 AR DEFB4A
7 meibomian cyst 10.3 AR KRT7
8 paget disease, extramammary 10.3 AR KRT7
9 oral candidiasis 10.3 DEFB1 DEFB4A
10 sebaceous gland disease 10.3 AR DEFB4A
11 eccrine papillary adenocarcinoma 10.3 KRT7 PGR
12 localized scleroderma 10.3 DEFB1 DEFB4A
13 papillary adenocarcinoma 10.3 KRT7 PGR
14 endosalpingiosis 10.3 KRT7 PGR
15 infiltrative basal cell carcinoma 10.3 AR KRT7
16 cribriform carcinoma 10.3 KRT7 PGR
17 benign metastasizing leiomyoma 10.3 KRT7 PGR
18 adenoid basal cell carcinoma 10.3 KRT7 PGR
19 pancreatic serous cystadenoma 10.3 KRT7 PGR
20 cystadenoma 10.3 KRT7 PGR
21 papillary serous adenocarcinoma 10.3 KRT7 PGR
22 endometrial squamous cell carcinoma 10.3 AR PGR
23 glycogen-rich clear cell breast carcinoma 10.3 KRT7 PGR
24 apocrine adenocarcinoma 10.3 AR PGR
25 peritoneal benign neoplasm 10.2 AR PGR
26 gender identity disorder 10.2 AR PGR
27 intrahepatic bile duct adenoma 10.2 KRT19 KRT7
28 diffuse peritoneal leiomyomatosis 10.2 AR PGR
29 anal gland adenocarcinoma 10.2 KRT19 KRT7
30 proliferating trichilemmal cyst 10.2 KRT19 KRT7
31 breast adenoid cystic carcinoma 10.2 AR PGR
32 anus adenocarcinoma 10.2 KRT19 KRT7
33 bartholin's gland disease 10.2 AR PGR
34 renal pelvis adenocarcinoma 10.2 KRT19 KRT7
35 cutaneous adenocystic carcinoma 10.2 KRT19 KRT7
36 dermoid cyst 10.2 KRT7 PGR
37 sertoli-leydig cell tumor 10.2 KRT7 PGR
38 bladder carcinoma in situ 10.2 KRT19 KRT7
39 papillary hidradenoma 10.2 AR PGR
40 malignant leydig cell tumor 10.2 KRT19 KRT7
41 sclerosing hemangioma 10.2 KRT7 PGR
42 breast secretory carcinoma 10.2 KRT7 PGR
43 eccrine adenocarcinoma 10.2 KRT19 KRT7
44 anal canal adenocarcinoma 10.2 KRT19 KRT7
45 morpheaform basal cell carcinoma 10.2 AR KRT19
46 chondroid lipoma 10.2 KRT19 KRT7
47 anterior cranial fossa meningioma 10.2 PGR PLG
48 cystitis cystica 10.2 AR KRT7
49 renal pelvis carcinoma 10.2 KRT19 KRT7
50 pancreatic mucinous cystadenoma 10.2 KRT7 PGR

Graphical network of the top 20 diseases related to Corneal Abscess:



Diseases related to Corneal Abscess

Symptoms & Phenotypes for Corneal Abscess

MGI Mouse Phenotypes related to Corneal Abscess:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.02 AR KRT19 PGR PLG PTEN

Drugs & Therapeutics for Corneal Abscess

Drugs for Corneal Abscess (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Formaldehyde Approved, Vet_approved 50-00-0 712
2 Anti-Infective Agents
3 Disinfectants

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 CD160 Expression in Retinal Vessels is Associated With Retinal Neovascular Diseases Completed NCT03940664

Search NIH Clinical Center for Corneal Abscess

Genetic Tests for Corneal Abscess

Anatomical Context for Corneal Abscess

MalaCards organs/tissues related to Corneal Abscess:

42
Breast, Eye, Lung, Skin, Ovary, Prostate, Thymus

Publications for Corneal Abscess

Articles related to Corneal Abscess:

(show all 20)
# Title Authors Year
1
Corneal abscess due to Moraxella nonliquefaciens. ( 30128157 )
2018
2
360 Degree Deep Corneal Vascularization In A Case Of Endophthalmitis With Corneal Abscess. ( 28718272 )
2017
3
First reported case of a corneal abscess caused by Massilia timonae. ( 26279207 )
2016
4
Corneal abscess caused by Bipolaris spicifera. ( 21623109 )
2011
5
Over-Treated Corneal Abscess May Be Toxic Keratopathy. ( 20737055 )
2010
6
Intracameral recombinant tissue plasminogen activator for refractory glaucoma secondary to a fungal corneal abscess. ( 19888435 )
2009
7
Effect of voriconazole on a corneal abscess caused by fusarium. ( 15606478 )
2004
8
Endophthalmitis after Lasiodiplodia theobromae corneal abscess. ( 9143896 )
1997
9
Psoriatic corneal abscess. ( 7785699 )
1995
10
Topical and systemic Ofloxacin (Tarivid) in the treatment of Gentamycin-resistant Pseudomonas corneal abscess. ( 22827204 )
1993
11
"Cold" corneal abscess in psoriasis: a case report. ( 2628702 )
1989
12
Marginal corneal abscess associated with adult chlamydial ophthalmia. ( 3191080 )
1988
13
Conjunctival flaps in the treatment of refractory pseudomonas corneal abscess. ( 3504115 )
1986
14
Isolation of Klebsiella ozaenae from a corneal abscess. ( 3993631 )
1985
15
Corneal abscess from soft contact lenses. ( 6593690 )
1984
16
Central corneal abscess. ( 1275041 )
1976
17
A corneal abscess due to the fungus Botryodiplodia theobromae. ( 1148913 )
1975
18
Isolation of a new Moraxella from a corneal abscess. ( 5022507 )
1972
19
Deep fungal corneal abscess. Combined corticosteroid therapy. ( 4938789 )
1971
20
Streptomycin treatment of a corneal abscess caused by Escherichia coli. ( 20994642 )
1946

Variations for Corneal Abscess

Expression for Corneal Abscess

Search GEO for disease gene expression data for Corneal Abscess.

Pathways for Corneal Abscess

Pathways related to Corneal Abscess according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.99 AR PTEN RAD51

GO Terms for Corneal Abscess

Biological processes related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 prostate gland growth GO:0060736 8.96 AR PTEN
2 tertiary branching involved in mammary gland duct morphogenesis GO:0060748 8.62 AR PGR

Molecular functions related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear receptor activity GO:0004879 9.26 AR PGR
2 steroid binding GO:0005496 9.16 AR PGR
3 enzyme binding GO:0019899 9.02 AR PGR PLG PTEN RAD51
4 CCR6 chemokine receptor binding GO:0031731 8.96 DEFB1 DEFB4A

Sources for Corneal Abscess

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....