MCID: CRN004
MIFTS: 25

Corneal Abscess

Categories: Neuronal diseases

Aliases & Classifications for Corneal Abscess

MalaCards integrated aliases for Corneal Abscess:

Name: Corneal Abscess 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11543
ICD9CM 34 370.55
NCIt 50 C26969
SNOMED-CT 67 64366002
ICD10 32 H16.31
UMLS 70 C0155091

Summaries for Corneal Abscess

MalaCards based summary : Corneal Abscess is related to psoriasis and keratitis, hereditary. An important gene associated with Corneal Abscess is SCGB1D1 (Secretoglobin Family 1D Member 1), and among its related pathways/superpathways are Defensins and Staphylococcus aureus infection. Affiliated tissues include eye, endothelial and lung.

Related Diseases for Corneal Abscess

Diseases related to Corneal Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 psoriasis 28.2 SLPI SLC12A8 PI3 FBXL19 DEFB4A CCHCR1
2 keratitis, hereditary 10.2
3 pustular psoriasis 10.1 SLPI PI3
4 farmer's lung 10.1 SLPI PI3
5 pasteurellosis 10.1 SLPI PI3
6 vaginitis 10.0 SLPI DEFB4A
7 vaginal disease 10.0 SLPI DEFB4A
8 candidiasis 10.0 DEFB4A DEFB1
9 dacryocystitis 10.0 DEFB4A DEFB1
10 acute inflammation of lacrimal passage 10.0 DEFB4A DEFB1
11 osteonecrosis of the jaw 10.0 DEFB4A DEFB1
12 bacterial vaginosis 10.0 PI3 DEFB4A
13 gingivitis 10.0 SLPI DEFB4A
14 keratopathy 10.0
15 pustulosis of palm and sole 10.0
16 endophthalmitis 10.0
17 conjunctivitis 10.0
18 vulvovaginal candidiasis 9.9 DEFB4A DEFB1
19 bacterial pneumonia 9.9 SLPI DEFB4A
20 tonsillitis 9.9 DEFB4A DEFB1
21 peptic ulcer disease 9.9 DEFB4A DEFB1
22 psoriasis 8 9.9 SLC12A8 CCHCR1
23 salmonellosis 9.9 DEFB4A DEFB1
24 psoriasis 10 9.9 SLC12A8 CCHCR1
25 psoriasis 7 9.9 SLC12A8 CCHCR1
26 aggressive periodontitis 9.8 DEFB4A DEFB1
27 intraocular pressure quantitative trait locus 9.8
28 chlamydia 9.8
29 urethritis 9.8
30 iritis 9.8
31 rhinitis 9.8
32 atrophic rhinitis 9.8
33 corneal ulcer 9.8
34 impetigo 9.8
35 ophthalmia neonatorum 9.8
36 bacterial conjunctivitis 9.8
37 fungal keratitis 9.8
38 oral candidiasis 9.8 SLPI DEFB4A DEFB1
39 periodontitis 9.8 DEFB4A DEFB1
40 pulmonary disease, chronic obstructive 9.8 SLPI PI3 DEFB1
41 allergic contact dermatitis 9.8 PI3 DEFB4A
42 deep keratitis 9.7 SLPI SLC12A8 SCGB1D1 PI3
43 acne 9.6 DEFB4A DEFB1
44 psoriasis 6 9.6 SLC12A8 FBXL19 CCHCR1
45 cystic fibrosis 9.5 SLPI PI3 DEFB4A DEFB1

Graphical network of the top 20 diseases related to Corneal Abscess:



Diseases related to Corneal Abscess

Symptoms & Phenotypes for Corneal Abscess

Drugs & Therapeutics for Corneal Abscess

Search Clinical Trials , NIH Clinical Center for Corneal Abscess

Genetic Tests for Corneal Abscess

Anatomical Context for Corneal Abscess

MalaCards organs/tissues related to Corneal Abscess:

40
Eye, Endothelial, Lung

Publications for Corneal Abscess

Articles related to Corneal Abscess:

(show top 50) (show all 135)
# Title Authors PMID Year
1
Severe Keratitis and Corneal Perforation by Paenibacillus glucanolyticus. 61
33264149 2020
2
Prognostic Factors Affecting Graft Survival in Patients Undergoing Penetrating Keratoplasty for Infectious Keratitis. 61
33389931 2020
3
Ocular basidiobolomycosis - Rare presentation: A case report. 61
32317530 2020
4
Equine non-healing corneal ulcers: a retrospective evaluation of 57 cases (2001-2017). 61
32325498 2020
5
Non-typeable Streptococcus pneumoniae infection in a medical center in Taiwan after wide use of pneumococcal conjugate vaccine. 61
29804657 2020
6
Corneal perforation: the most feared complication of corneal abscess. 61
32499850 2020
7
Microbiologic profile of the mycosic absess on a reference center in Tunisia. 61
31729735 2019
8
Polymicrobial Keratitis With Cryptococcus curvatus, Candida parapsilosis, and Stenotrophomonas maltophilia After Penetrating Keratoplasty: A Rare Case Report With Literature Review. 61
29944507 2019
9
Listeria monocytogenes and ocular abscess: an atypical but yet potential association. 61
29086326 2018
10
Corneal abscess due to Moraxella nonliquefaciens. 61
30128157 2018
11
Results of therapeutic penetrating keratoplasty for bacterial and fungal keratitis. 61
27723008 2017
12
Surgical treatment of Metarhizium anisopliae sclerokeratitis and endophthalmitis. 61
28643721 2017
13
Topical non-steroidal anti-inflammatory drugs for analgesia in traumatic corneal abrasions. 61
28516471 2017
14
Intracorneal Amphotericin B Injection in a Case of Indolent Candidal Keratitis. 61
28658821 2017
15
Lacrimal gland ductal carcinomas: Clinical, Morphological and Genetic characterization and implications for targeted treatment. 61
27808478 2017
16
360 Degree Deep Corneal Vascularization In A Case Of Endophthalmitis With Corneal Abscess. 61
28718272 2017
17
Corneal Cross-Linking as a Treatment for Fungal Keratitis Associated with Corneal Melting. 61
28611646 2017
18
Fusarium dimerum Species Complex (Fusarium penzigii) Keratitis After Corneal Trauma. 61
27631818 2016
19
Multiorganism, drug-resistant keratitis treated by corneal crosslinking. 61
26833230 2016
20
[Prolonged topical natamycin 5‚ÄČ% therapy before and after keratoplasty for Fusarium keratitis]. 61
26205744 2016
21
Post-traumatic endophthalmitis in 143 eyes of children and adolescents from India. 61
26869162 2016
22
First reported case of a corneal abscess caused by Massilia timonae. 61
26279207 2016
23
Ocular complications in children after hematopoietic stem cell transplantation without total body irradiation. 61
25708560 2015
24
Multidrug resistant Fusarium keratitis. 61
25443198 2015
25
Alternaria is an Infrequent Cause of Keratitis: A Case Report and Review of the Literature. 61
25794328 2015
26
[Non-traumatic corneal perforations: Therapeutic modalities]. 61
25891769 2015
27
Severe microbial keratitis and associated perforation after corneal crosslinking for keratoconus. 61
25435381 2015
28
Infectious crystalline keratopathy caused by Pseudomonas fluorescens. 61
24113463 2015
29
Severe Staphylococcus lugdunensis keratitis. 61
25082203 2015
30
[THE FIRST CASE OF OCULAR THELAZIASIS IN CROATIA]. 61
29087095 2015
31
Femtosecond Laser-Assisted Intra-Corneal Drug Delivery. 61
24506334 2015
32
Corneal Infection Therapy with Topical Bacteriophage Administration. 61
26862360 2015
33
Keratitis after corneal projection of biological fluids: a possible occupational prejudice? 61
25291778 2014
34
Topical voriconazole therapy of Purpureocillium lilacinum keratitis that occurred in disposable soft contact lens wearers. 61
24974133 2014
35
Histopathological Studies on Rabbits Infected by Bacteria Causing Infectious Keratitis in Human through Eye Inoculation. 61
25505861 2014
36
Fungal keratitis secondary to Scedosporium apiospermum infection and successful treatment with surgical and medical intervention. 61
23612853 2014
37
Alternaria keratitis and hypopyon after clear-cornea phacoemulsification. 61
24461506 2014
38
[Corneal abscess: serious complication of neglected and poorly managed corneal trauma]. 61
25821547 2014
39
Preparation and characterization of a hydrogel carrier to deliver gatifloxacin and its application as a therapeutic contact lens for bacterial keratitis therapy. 61
24057809 2013
40
Rehabilitation of an Infected Eye with an Acrylic Ball Implant and a Custom made Scleral Ocular Prosthesis. 61
24431757 2013
41
Long-term follow-up after successful treatment of Pythium insidiosum keratitis in Israel. 61
23627654 2013
42
Loss of sight caused by calcium hydroxide paste accidentally splashed into the eye during endodontic treatment: case report. 61
24195193 2013
43
Rapid diagnosis of acanthamoeba keratitis using non-nutrient agar with a lawn of E. coli. 61
23514313 2013
44
Acanthamoeba T4 genotype associated with keratitis infections in Tunisia. 61
23052779 2013
45
Bacillus cereus infection after Descemet stripping endothelial keratoplasty. 61
22262217 2012
46
Loss of sight caused by calcium hydroxide paste accidentally splashed into the eye during endodontic treatment: case report. 61
22673219 2012
47
Pseudomonas keratitis 4 years after laser in situ keratomileusis. 61
21666521 2011
48
[Severe keratomycosis due to Fusarium solani induced by a telluric foreign body: About a case in moroccan Sahara]. 61
24451564 2011
49
Corneal abscess caused by Bipolaris spicifera. 61
21623109 2011
50
Unusual presentation of phacolytic glaucoma: simulating microbial keratitis. 61
22606478 2011

Variations for Corneal Abscess

Expression for Corneal Abscess

Search GEO for disease gene expression data for Corneal Abscess.

Pathways for Corneal Abscess

Pathways related to Corneal Abscess according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.13 PI3 DEFB4A DEFB1
2 10.94 DEFB4A DEFB1

GO Terms for Corneal Abscess

Cellular components related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 SLPI SCGB1D1 PI3 DEFB4A DEFB1
2 Golgi lumen GO:0005796 9.16 DEFB4A DEFB1
3 extracellular space GO:0005615 9.02 SLPI SCGB1D1 PI3 DEFB4A DEFB1

Biological processes related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.54 SLPI DEFB4A DEFB1
2 negative regulation of peptidase activity GO:0010466 9.43 SLPI PI3
3 defense response to Gram-positive bacterium GO:0050830 9.4 DEFB4A DEFB1
4 defense response to bacterium GO:0042742 9.33 SLPI DEFB4A DEFB1
5 defense response to Gram-negative bacterium GO:0050829 9.32 DEFB4A DEFB1
6 antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 9.26 DEFB4A DEFB1
7 antimicrobial humoral response GO:0019730 9.13 PI3 DEFB4A DEFB1
8 antibacterial humoral response GO:0019731 8.8 SLPI PI3 DEFB1

Molecular functions related to Corneal Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 9.26 SLPI PI3
2 serine-type endopeptidase inhibitor activity GO:0004867 9.16 SLPI PI3
3 endopeptidase inhibitor activity GO:0004866 8.96 SLPI PI3
4 CCR6 chemokine receptor binding GO:0031731 8.62 DEFB4A DEFB1

Sources for Corneal Abscess

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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