MCID: CRN023
MIFTS: 24

Corneal Deposit

Categories: Eye diseases

Aliases & Classifications for Corneal Deposit

MalaCards integrated aliases for Corneal Deposit:

Name: Corneal Deposit 12 54 15 71
Deposits - Cornea 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11547
ICD9CM 34 371.10
SNOMED-CT 67 74460005
ICD10 32 H18.00
UMLS 71 C0162281

Summaries for Corneal Deposit

MalaCards based summary : Corneal Deposit, also known as deposits - cornea, is related to corneal edema and granular corneal dystrophy. An important gene associated with Corneal Deposit is TGFBI (Transforming Growth Factor Beta Induced). Affiliated tissues include eye, endothelial and heart, and related phenotypes are homeostasis/metabolism and vision/eye

Wikipedia : 74 The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.... more...

Related Diseases for Corneal Deposit

Diseases related to Corneal Deposit via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 corneal edema 29.6 TGFBI KRT3
2 granular corneal dystrophy 29.5 TGFBI TBCD KRT3 GCDH CHST6
3 recurrent corneal erosion 29.2 TGFBI TBCD KRT3 CHST6
4 corneal dystrophy, avellino type 28.7 UBIAD1 TGFBI TBCD KRT3 GCDH CHST6
5 lattice corneal dystrophy 28.6 TGFBI TBCD TACSTD2 GCDH CHST6
6 corneal dystrophy 27.6 UBIAD1 TGFBI TBCD TACSTD2 PFDN6 KRT3
7 corneal argyrosis 11.5
8 stromal corneal dystrophy 10.2 UBIAD1 TGFBI
9 postinflammatory pulmonary fibrosis 10.2 GCDH CYP4V2
10 keratopathy 10.2
11 keratitis, hereditary 10.1
12 myeloma, multiple 10.1
13 cataract 10.1
14 irregular astigmatism 10.1 TGFBI KRT3
15 monoclonal gammopathy of uncertain significance 10.0
16 keratoconjunctivitis 10.0
17 corneal dystrophy, fleck 10.0 TGFBI TBCD
18 schnyder corneal dystrophy 10.0 UBIAD1 TGFBI KRT3
19 arcus corneae 10.0 UBIAD1 LCAT
20 epithelial basement membrane dystrophy 10.0 TGFBI TBCD CHST6
21 immune deficiency disease 9.9
22 vernal keratoconjunctivitis 9.9
23 fuchs' endothelial dystrophy 9.9 TGFBI KRT3 CHST6
24 macular dystrophy, corneal 9.8 UBIAD1 TGFBI KRT3 CHST6
25 spondyloarthropathy 1 9.8
26 bietti crystalline corneoretinal dystrophy 9.8
27 fabry disease 9.8
28 graft-versus-host disease 9.8
29 herpes simplex virus keratitis 9.8
30 keratoconus 9.8
31 myopia 9.8
32 inflammatory spondylopathy 9.8
33 shipyard eye 9.8
34 uveitis 9.8
35 hyperparathyroidism 9.8
36 giant papillary conjunctivitis 9.8
37 papillary conjunctivitis 9.8
38 conjunctivitis 9.8
39 acquired immunodeficiency syndrome 9.8
40 spondylitis 9.8
41 fundus dystrophy 9.8
42 lupus erythematosus 9.8
43 48,xyyy 9.8
44 scleromyxedema 9.8
45 cytomegalovirus infection 9.8
46 amoebic keratitis 9.8
47 inherited retinal disorder 9.8
48 discoid lupus erythematosus 9.8
49 corneal dystrophy, posterior polymorphous, 1 9.8 UBIAD1 TGFBI KRT3 CHST6
50 corneal dystrophy, lisch epithelial 9.7 UBIAD1 TBCD KRT3 CHST6

Graphical network of the top 20 diseases related to Corneal Deposit:



Diseases related to Corneal Deposit

Symptoms & Phenotypes for Corneal Deposit

MGI Mouse Phenotypes related to Corneal Deposit:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 CTNS CYP4V2 FAS GCDH GLA LCAT
2 vision/eye MP:0005391 9.23 CHST6 CTNS CYP4V2 FAS GLA LCAT

Drugs & Therapeutics for Corneal Deposit

Search Clinical Trials , NIH Clinical Center for Corneal Deposit

Genetic Tests for Corneal Deposit

Anatomical Context for Corneal Deposit

MalaCards organs/tissues related to Corneal Deposit:

40
Eye, Endothelial, Heart

Publications for Corneal Deposit

Articles related to Corneal Deposit:

(show all 16)
# Title Authors PMID Year
1
Reversible postoperative visual loss from ciprofloxacin corneal deposit. 61
31208907 2019
2
Epidemiological profile of fungal keratitis in Sfax (Tunisia). 61
25442924 2014
3
Corneal deposit after topical ciprofloxacin as postoperative medication after cataract surgery. 61
25103659 2014
4
Corneal deposit of ciprofloxacin after laser assisted subepithelial keratomileusis procedure: a case report. 61
20634934 2010
5
The importance of amiodarone pulmonary toxicity in the differential diagnosis of a patient with dyspnea awaiting a heart transplant. 61
17057913 2006
6
Transient band-like keratopathy after treatment for seborrheic dermatitis. 61
15778610 2005
7
Morphometric analysis of deposits in granular and lattice corneal dystrophy: histopathologic implications for phototherapeutic keratectomy. 61
15097134 2004
8
Avellino corneal dystrophy after LASIK. 54
15019320 2004
9
[Corneal crystalline deposits in monoclonal gammapathy: a report of two cases]. 61
11591915 2001
10
Different recurrence patterns after phototherapeutic keratectomy in the corneal dystrophy resulting from homozygous and heterozygous R124H BIG-H3 mutation. 54
11476689 2001
11
Findings in the anterior segment on ultrasound biomicroscopy in Maroteaux-Lamy syndrome. 61
11322427 2001
12
Immunohistology of kerato-epithelin in corneal stromal dystrophies associated with R124 mutations of the BIGH3 gene. 54
11262611 2000
13
Unusual corneal deposit after the topical use of cyclosporine as eyedrops. 61
11078849 2000
14
Immunolocalization of beta ig-h3 protein in 5q31-linked corneal dystrophies and normal corneas. 54
9930162 1999
15
Ceasing of epithelisation and deposit formation of unknown origin on the cornea. 61
1721762 1991
16
Calcific band keratopathy after intraocular chondroitin sulfate. 61
3307722 1987

Variations for Corneal Deposit

Expression for Corneal Deposit

Search GEO for disease gene expression data for Corneal Deposit.

Pathways for Corneal Deposit

GO Terms for Corneal Deposit

Cellular components related to Corneal Deposit according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.17 TGFBI TACSTD2 LCAT KRT3 GLA FAS
2 lateral plasma membrane GO:0016328 8.96 TBCD TACSTD2

Biological processes related to Corneal Deposit according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 8.8 TGFBI TACSTD2 CYP4V2

Sources for Corneal Deposit

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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