Aliases & Classifications for Corneal Disease

MalaCards integrated aliases for Corneal Disease:

Name: Corneal Disease 12 15
Corneal Diseases 55 44 73
Corneal Disorders 43

Classifications:



External Ids:

Disease Ontology 12 DOID:10124
ICD10 33 H18.9 H17.9
ICD9CM 35 371.9
MeSH 44 D003316
NCIt 50 C26731
SNOMED-CT 68 15250008
UMLS 73 C0010034

Summaries for Corneal Disease

MedlinePlus : 43 Your cornea is the outermost layer of your eye. It is clear and shaped like a dome. The cornea helps to shield the rest of the eye from germs, dust, and other harmful matter. It also helps your eye to focus. If you wear contact lenses, they float on top of your corneas. Problems with the cornea include Refractive errors Allergies Infections Injuries Dystrophies - conditions in which parts of the cornea lose clarity due to a buildup of cloudy material Treatments of corneal disorders include medicines, corneal transplantation, and corneal laser surgery. NIH: National Eye Institute

MalaCards based summary : Corneal Disease, also known as corneal diseases, is related to keratitis, hereditary and corneal dystrophy, avellino type, and has symptoms including eye manifestations An important gene associated with Corneal Disease is TGFBI (Transforming Growth Factor Beta Induced), and among its related pathways/superpathways is Hypertrophy Model. The drugs Bevacizumab and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include eye, endothelial and testes, and related phenotypes are homeostasis/metabolism and immune system

Wikipedia : 76 The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.... more...

Related Diseases for Corneal Disease

Diseases related to Corneal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 78)
# Related Disease Score Top Affiliating Genes
1 keratitis, hereditary 31.9 GJB2 GJB6 TLR9
2 corneal dystrophy, avellino type 31.5 CHST6 TGFBI
3 corneal dystrophy, meesmann 31.4 CHST6 COL8A2 KRT12 KRT3 TGFBI
4 keratoconus 31.4 VSX1 TGFBI KRT3 KRT12 IL1A GSN
5 corneal dystrophy, posterior polymorphous, 1 31.3 COL8A2 SLC4A11 TGFBI VSX1 ZEB1
6 limbal stem cell deficiency 30.2 IL1A KRT12 KRT3
7 kid syndrome 29.9 GJB2 GJB6
8 keratoconjunctivitis sicca 29.8 IL1A NGF TLR9
9 keratoendotheliitis fugax hereditaria 11.3
10 keratoconus 9 10.9
11 corneal dystrophy, fuchs endothelial, 1 10.8
12 megalocornea 10.8
13 peters-plus syndrome 10.8
14 corneal dystrophy, fuchs endothelial, 4 10.8
15 corneal dystrophy, fuchs endothelial, 6 10.8
16 corneal dystrophy, fuchs endothelial, 8 10.8
17 sclerocornea 10.8
18 corneal dystrophy and perceptive deafness 10.8
19 corneal dystrophy, fuchs endothelial, 2 10.8
20 corneal dystrophy, fuchs endothelial, 3 10.8
21 corneal dystrophy, lattice type i 10.3 GSN TGFBI
22 corneal dystrophy, endothelial, x-linked 10.2 SLC4A11 VSX1
23 macular dystrophy, corneal 10.2 CHST6 KRT12 TGFBI
24 epithelial basement membrane dystrophy 10.2 COL8A2 IL1A TGFBI
25 deafness, autosomal dominant 24 10.2 GJB2 GJB6
26 tyrosinemia, type ii 10.2 CHST6 KRT12
27 algoneurodystrophy 10.2 LCAT NGF
28 pseudoainhum 10.2 GJB2 GJB6
29 rheumatic myocarditis 10.2 GSN IL1A
30 knuckle pads 10.2 GJB2 GJB6
31 knuckle pads, leukonychia, and sensorineural deafness 10.2 GJB2 GJB6
32 corneal granular dystrophy 10.2 CHST6 KRT12 KRT3 TGFBI
33 deafness, x-linked 2 10.2 GJB2 GJB6
34 epithelial and subepithelial dystrophy 10.2 CHST6 KRT12 KRT3 TGFBI
35 hodgkin's lymphoma, nodular sclerosis 10.2 GJB2 GJB6
36 dfnb1 10.2 GJB2 GJB6
37 vohwinkel syndrome 10.2 GJB2 GJB6
38 bone inflammation disease 10.2 IL1A NLRP3 TLR9
39 epithelial-stromal tgfbi dystrophy 10.2 CHST6 GSN KRT12 TGFBI
40 corneal dystrophy, gelatinous drop-like 10.2 CHST6 GSN KRT12 TGFBI
41 corneal dystrophy, posterior polymorphous, 2 10.1 COL8A2 SLC4A11 VSX1 ZEB1
42 keratoconus 1 10.1 VSX1 ZNF469
43 amyloidosis 10.1 GSN NLRP3 TGFBI
44 auditory system disease 10.1 GJB2 GJB6 TLR9
45 corneal degeneration 10.1 KRT12 LCAT TGFBI VSX1
46 deafness, autosomal recessive 1a 10.1 GJB2 GJB6
47 herpes simplex 10.1
48 corneal endothelial dystrophy 10.1 CHST6 COL8A2 KRT12 KRT3 SLC4A11 TGFBI
49 deafness, autosomal recessive 23 10.0 GJB2 GJB6
50 corneal dystrophy, posterior polymorphous, 3 10.0 COL8A2 SLC4A11 TGFB2 VSX1 ZEB1

Graphical network of the top 20 diseases related to Corneal Disease:



Diseases related to Corneal Disease

Symptoms & Phenotypes for Corneal Disease

UMLS symptoms related to Corneal Disease:


eye manifestations

MGI Mouse Phenotypes related to Corneal Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.93 GJB2 GJB6 GSN IL1A LCAT NGF
2 immune system MP:0005387 9.65 AGBL1 GJB2 GJB6 GSN IL1A NLRP3
3 vision/eye MP:0005391 9.36 CHST6 COL8A2 GJB2 KRT12 LCAT NGF

Drugs & Therapeutics for Corneal Disease

Drugs for Corneal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 559)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 216974-75-3
2
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 137-58-6 3676
3
Racepinephrine Approved Phase 4,Not Applicable 329-65-7 838
4
Epinephrine Approved, Vet_approved Phase 4,Not Applicable 51-43-4 5816
5
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9004-61-9 53477741
6
Fluorometholone Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 426-13-1 9878
7
Loteprednol Approved, Experimental Phase 4,Phase 3,Phase 2,Not Applicable 82034-46-6, 129260-79-3 9865442 444025
8
Metformin Approved Phase 4 657-24-9 14219 4091
9
Ranibizumab Approved Phase 4,Phase 2,Phase 3,Phase 1 347396-82-1 459903
10
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 104987-11-3 445643 439492
11
Tocopherol Approved, Investigational Phase 4,Phase 2,Not Applicable 1406-66-2 14986
12
Povidone Approved Phase 4,Phase 3,Phase 2,Not Applicable 9003-39-8
13
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 22916-47-8 4189
14
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-24-8 5755
15
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 302-25-0
16
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2921-57-5
17
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83-43-2 6741
18
Latanoprost Approved, Investigational Phase 4,Phase 3 130209-82-4 5311221 5282380
19
Levofloxacin Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 100986-85-4 149096
20
Ethinyl Estradiol Approved Phase 4,Phase 3,Phase 2 57-63-6 5991
21
Ofloxacin Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 82419-36-1 4583
22
Moxifloxacin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 354812-41-2, 151096-09-2 152946
23
Polyestradiol phosphate Approved Phase 4,Phase 3,Phase 2 28014-46-2
24
Norgestimate Approved, Investigational Phase 4,Phase 3,Phase 2 35189-28-7 6540478
25
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-28-2 5757
26 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 979-32-8
27
Glycerol Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 56-81-5 753
28
Dipivefrin Approved Phase 4,Phase 3,Phase 1,Not Applicable 52365-63-6 3105
29
Iodine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 7553-56-2 807
30
Povidone-iodine Approved Phase 4,Phase 3,Phase 2,Not Applicable 25655-41-8
31
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 1177-87-3
32
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-02-2 5743
33
Vancomycin Approved Phase 4,Not Applicable 1404-90-6 14969 441141
34
Petrolatum Approved, Investigational Phase 4,Phase 3,Not Applicable 8009-03-8
35
Ganciclovir Approved, Investigational Phase 4,Phase 2,Not Applicable 82410-32-0 3454
36
Tobramycin Approved, Investigational Phase 4,Phase 3,Not Applicable 32986-56-4 36294 5496
37
Zinc Approved, Investigational Phase 4,Phase 2,Not Applicable 7440-66-6
38
Natamycin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 7681-93-8 5281099
39
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 564-25-0 54671203
40
Acyclovir Approved Phase 4,Phase 3 59277-89-3 2022
41
Flavin Mononucleotide Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 146-17-8 643976
42
Titanium dioxide Approved Phase 4 13463-67-7
43
Ketorolac Approved Phase 4,Phase 2 66635-83-4, 74103-06-3 3826
44
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
45
Azithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 83905-01-5 55185 447043
46
Tetracycline Approved, Vet_approved Phase 4,Not Applicable 60-54-8 5353990
47
Ethanol Approved Phase 4,Phase 2,Not Applicable 64-17-5 702
48
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 124-94-7 31307
49
Nepafenac Approved, Investigational Phase 4 78281-72-8 151075
50 Lifitegrast Approved Phase 4,Phase 3,Phase 2,Not Applicable 1025967-78-5

Interventional clinical trials:

(show top 50) (show all 1512)
# Name Status NCT ID Phase Drugs
1 Safety and Efficacy Study of Artificial Cornea Unknown status NCT01018888 Phase 4
2 The Impact of Topical Prostaglandins on the Biomechanical Properties of the Cornea in Patients With Open Angle Glaucoma Unknown status NCT02388360 Phase 4 topical prostaglandin analogs
3 Strategies for Management of Corneal Neovascularisation Unknown status NCT02594423 Phase 4 Bevacizumab
4 TRPV Expression in Subjects With Sensitive Skin Unknown status NCT01871883 Phase 4
5 Hyaluronic Acid Gels for Upper Lid Retraction in Active Stage Thyroid Eye Disease Unknown status NCT01738243 Phase 4 Hyaluronic Acid Gel injection;Saline injection
6 Comparison of Next Generation Laser Techniques of Myopia Correction: iDesign vs. SMILE Unknown status NCT03001401 Phase 4
7 0.3% Sodium Hyaluronate in the Treatment of Dry Eye of Diabetic Patients Unknown status NCT02595606 Phase 4 0.3% Sodium Hyaluronate
8 Safety and Efficacy of Lotemax Versus FML in Subjects Undergoing PRK for the Correction of Mild to Moderate Myopia, 3- Month Follow-up Study Unknown status NCT02974387 Phase 4 Fluorometholone(FML);Loteprednol (Lotemax)
9 Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity Unknown status NCT02438020 Phase 4 Metformin
10 Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty Unknown status NCT01225250 Phase 4
11 Evaluating Results of Neusidl Corneal Inserter in Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) Unknown status NCT01357122 Phase 4
12 Evaluation of Changes in the Parameters of Optical Coherence Tomography After Intravitreal Injection of Lucentis Unknown status NCT01669447 Phase 4
13 Topical Tacrolimus in Vernal Keratoconjunctivitis Unknown status NCT02456025 Phase 4 Topical tacrolimus
14 Effect of Intense Pulse Light (IPL) Treatment on Tear Film Osmolarity Unknown status NCT02992535 Phase 4
15 Oral Nutrition Impact on Tear Film Unknown status NCT01561040 Phase 4
16 Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity Unknown status NCT01386073 Phase 4 FreshKote;Systane
17 Altaire Gel Forming Solution Versus Refresh Tears for the Treatment of Dry Eye Signs and Symptoms Unknown status NCT01382810 Phase 4 Altaire Gel forming solution;Refresh Tears
18 Comparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry Eyes Unknown status NCT00704275 Phase 4 0.05% cyclosporin eye drop
19 Topical Cyclosporine for the Treatment of Dry Eye in Patients Infected With the Human Immunodeficiency Virus Unknown status NCT00797030 Phase 4 cyclosporine and sodium carboximethycellulose;sodium carboximethycellulose
20 Cornea Preservation Time Study Completed NCT01537393 Phase 4
21 Corneal Thickness Changes During Corneal Collagen Cross-linking With Ultraviolet-A Irradiation and Riboflavin Completed NCT01485211 Phase 4 cross-linking with hypo-osmolar riboflavin
22 Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty Completed NCT01853696 Phase 4 loteprednol etabonate;prednisolone acetate 1%
23 Dermal Penetration of the Titanium Dioxide in Anthelios SX SPF40 Cream Completed NCT01021787 Phase 4 Titanium dioxide
24 Ophthalmic Findings During 10-year Enzyme Substitution of Danish Fabry Patients. Completed NCT01997489 Phase 4 Enzyme replacement
25 Kynex Versus Refresh Plus Study in Subject With Dry Eye Completed NCT00809198 Phase 4
26 The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma Completed NCT01369771 Phase 4 Tafluprost 0.0015%
27 Lotoprednol vs. Prednisolone and Fluorometholone Completed NCT03123614 Phase 4 Loteprednol Etabonate 0.5% Oph Gel;Prednisolone Acetate 1% Oph Susp
28 Effect on Wound Healing of Vigamox Versus Cravit Completed NCT00840580 Phase 4 Moxifloxacin 0.5% ophthalmic solution (Vigamox);Levofloxacin 0.5% ophthalmic solution (Cravit)
29 Pain Management in Corneal Collagen Crosslinking for Keratoconus Completed NCT02867176 Phase 4 Gabapentin;Ketorolac
30 The Effect of Bevacizumab on Corneal Neovascularization Completed NCT00797303 Phase 4 Bevacizumab
31 Effect of Moisturising Creams on Skin Moisture in Atopic Dermatitis Completed NCT00846235 Phase 4
32 The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED Completed NCT02120079 Phase 4 Lotemax;Soothe Tired Eyes Lubricant Eye Drop (Artificial Tears)
33 Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear Completed NCT01015768 Phase 4
34 Partnership for Rapid Elimination of Trachoma Completed NCT00792922 Phase 4 Azithromycin;Azithromycin
35 A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry Eye Completed NCT02117687 Phase 4 carboxymethylcellulose 0.5%/glycerin 0.9%;sodium hyaluronate 0.18%
36 Role of Sub-Conjunctival Bevacizumab in Post Pterygium Excision Management Completed NCT01736449 Phase 4 Bevacizumab
37 Effects of Contact Lens Care Regimens on the Corneal Epithelium Completed NCT00349882 Phase 4 Marketed multipurpose disinfection regimen
38 Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function Completed NCT00560898 Phase 4 ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution;Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution;Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution;ProClear Lens Material soaked in Optifree RepleniSH Multipurpose Solution
39 Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C Completed NCT00599950 Phase 4 Mitomycin C and Photorefractive keratectomy (PRK)
40 Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia Completed NCT00347776 Phase 4 azithromycin;topical tetracycline
41 Comparison of Toric IOL Implantation and Opposite Clear Corneal Incision During Cataract Surgery to Correct Corneal Astigmatism Completed NCT01763151 Phase 4
42 2-Site Safety Study of Besivance Versus Vigamox Prophylactically in Routine Cataract Surgery Completed NCT01455233 Phase 4 besivance;vigamox
43 Mechanical vs. Alcohol Separation of the Corneal Epithelium During Surface Ablation Refractive Procedures Completed NCT00366808 Phase 4
44 Dropless™ vs. Less Drops™ Pharmaceutical Regimens After Cataract Surgery Completed NCT02819908 Phase 4 Imprimis Dropless;Imprimis Less Drops
45 Comparison of Functional Vision Provided by AMO Tecnis Z9000 and Alcon SA60AT Acrysof Completed NCT00459303 Phase 4
46 Soothe Versus Refresh Completed NCT00284999 Phase 4 Soothe;Refresh Tears
47 Comparison of Ex-PRESSTM Mini Glaucoma Shunt to Trabeculectomy in Subjects With Open Angle Glaucoma Completed NCT00444080 Phase 4
48 Povidone-iodine Antisepsis for Strabismus Surgery Completed NCT00461656 Phase 4 Preoperative conjunctival irrigation with 5% or 1.25% PI
49 Topical Cyclosporine for Vernal Keratoconjunctivitis (VKC) in Rwanda Completed NCT01211327 Phase 4 Cyclosporine A;Dexamethasone
50 GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients Completed NCT00598689 Phase 4 0.3% hypromellose

Search NIH Clinical Center for Corneal Disease

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: corneal diseases

Genetic Tests for Corneal Disease

Anatomical Context for Corneal Disease

MalaCards organs/tissues related to Corneal Disease:

41
Eye, Endothelial, Testes, T Cells, Small Intestine, Skin, Bone

Publications for Corneal Disease

Articles related to Corneal Disease:

(show top 50) (show all 240)
# Title Authors Year
1
Observation of corneal transplantation in peripheral corneal disease postoperatively. ( 29904417 )
2018
2
Attitudes and Perception Towards Eye Donation in Patients with Corneal Disease: A Case-controlled Population-based Study. ( 29652516 )
2018
3
Attenuated HSV-1 expressing a mutant form of ICP6 stimulates a strong immune response that protects mice against HSV-1-induced corneal disease. ( 29950407 )
2018
4
Impact of corneal disease from patients' and ophthalmologists' perspectives. ( 30207069 )
2018
5
A Review of the Cytokine IL-17 in Ocular Surface and Corneal Disease. ( 30230384 )
2018
6
Comparison of chlorhexidine disinfectant in vitro effect on environmental and ocular Acanthamoeba strains, the amoebic agents of human keratitis − an emerging sight-threatening corneal disease in Poland ( 30316219 )
2018
7
Comparison of ultrasonic pachymetry and Fourier-domain optical coherence tomography for measurement of corneal thickness in dogs with and without corneal disease. ( 30503546 )
2018
8
Investigating the Pathogenicity of VSX1 Missense Mutations and Their Association With Corneal Disease. ( 30535423 )
2018
9
Structural, ultrastructural, and morphometric study of the zebrafish ocular surface: a model for human corneal diseases? ( 29111817 )
2018
10
Optical coherence tomography for ocular surface and corneal diseases: a review. ( 29942817 )
2018
11
Mitochondrial dysfunction and oxidative stress in corneal disease. ( 28549842 )
2017
12
State of the Art and Beyond: Anterior Segment Diagnostics Genetic Diagnostics in Corneal Disease. ( 28590278 )
2017
13
Umbilical cord stem cells in the treatment of corneal disease. ( 28232219 )
2017
14
Keratoconus and Other Corneal Diseases: Pharmacologic Cross-Linking and Future Therapy. ( 27815790 )
2017
15
Novel Diagnostic and Therapeutic Methods in Ocular Surface and Corneal Diseases. ( 28491469 )
2017
16
City Lights: corneal diseases in Hollywood movies. ( 28576224 )
2017
17
The role of lipids in corneal diseases and dystrophies: a systematic review. ( 28782089 )
2017
18
Teleophthalmic Approach for Detection of Corneal Diseases: Accuracy and Reliability. ( 28820791 )
2017
19
A Novel Entity of Corneal Diseases with Irregular Posterior Corneal Surfaces: Concept and Clinical Relevance. ( 29016407 )
2017
20
Pattern of Corneal Diseases in Paediatric Age Group at a Tertiary Eye Care Center in Nepal. ( 29022953 )
2017
21
Nrf2, a Potential Therapeutic Target against Oxidative Stress in Corneal Diseases. ( 29209447 )
2017
22
Corneal Nerve Fiber Structure, Its Role in Corneal Function, and Its Changes in Corneal Diseases. ( 29238714 )
2017
23
Therapy for corneal diseases, layer by layer. ( 29296548 )
2017
24
Population-based assessment of vision-related quality of life in corneal disease: results from the CORE study. ( 26917676 )
2016
25
Keratoconus; a True Corneal Disease. ( 27195077 )
2016
26
In vivo confocal microscopic corneal images in health and disease with an emphasis on extracting features and visual signatures for corneal diseases: a review study. ( 26553917 )
2016
27
Aetiology-specific comparison of long-term outcome of deep anterior lamellar keratoplasty for corneal diseases. ( 26701685 )
2016
28
Detection of ectatic corneal diseases based on pentacam. ( 26777318 )
2016
29
Efficient Transduction of Corneal Stroma by Adeno-Associated Viral Serotype Vectors for Implications in Gene Therapy of Corneal Diseases. ( 27001051 )
2016
30
α-Lipoic Acid in Soluplus(®) Polymeric Nanomicelles for Ocular Treatment of Diabetes-Associated Corneal Diseases. ( 27103010 )
2016
31
Risk factors for visual impairment associated with corneal diseases in southern China. ( 27194904 )
2016
32
Cell Therapy of Corneal Diseases. ( 27631350 )
2016
33
Evaluation of a low-cost design keratoprosthesis in end-stage corneal disease: a preliminary study. ( 26271267 )
2015
34
Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice. ( 26398722 )
2015
35
Long-Term Results of the Boston Keratoprosthesis for Unilateral Corneal Disease. ( 26114818 )
2015
36
Comparing biometry in normal eyes of children with unilateral cataract/corneal disease to age-matched controls. ( 27363955 )
2015
37
Reinhard T, Larkin F (eds), Corneal Disease 2013, ISBN: 978-3-642-28746-6, Springer. ( 26371062 )
2015
38
Prevalence of corneal diseases in the rural Indian population: the Corneal Opacity Rural Epidemiological (CORE) study. ( 25395684 )
2015
39
Primary implantation of type I Boston keratoprosthesis in nonautoimmune corneal diseases. ( 25611395 )
2015
40
The role of oxidative stress in corneal diseases and injuries. ( 25803192 )
2015
41
Nanomedicine approaches for corneal diseases. ( 25941990 )
2015
42
A simple and non-contact optical imaging probe for evaluation of corneal diseases. ( 26429443 )
2015
43
Latest advances in the treatment of corneal diseases. ( 29018678 )
2015
44
Telemedicine for corneal disease in rural Nepal. ( 24906650 )
2014
45
Partial lamellar keratoplasty for peripheral corneal disease using a graft from the glycerin-preserved corneoscleral rim. ( 24796771 )
2014
46
Age distribution of various corneal diseases in China by histopathological examination of 3112 surgical specimens. ( 24722694 )
2014
47
Keratocyte progenitor cell transplantation: A novel therapeutic strategy for corneal disease. ( 23200457 )
2013
48
Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases. ( 23813972 )
2013
49
Cataract surgery in patients with corneal disease. ( 23197265 )
2013
50
Metaherpetic corneal disease in a dog associated with partial limbal stem cell deficiency and neurotrophic keratitis. ( 22958361 )
2013

Variations for Corneal Disease

Expression for Corneal Disease

Search GEO for disease gene expression data for Corneal Disease.

Pathways for Corneal Disease

Pathways related to Corneal Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.92 IL1A ZEB1

GO Terms for Corneal Disease

Cellular components related to Corneal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 COL8A2 GSN IL1A LCAT NGF NLRP3
2 connexin complex GO:0005922 8.96 GJB2 GJB6

Biological processes related to Corneal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.35 GJB6 IL1A NGF TGFB2 ZEB1
2 inner ear development GO:0048839 8.8 GJB2 GJB6 TGFB2

Molecular functions related to Corneal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 interleukin-1 receptor binding GO:0005149 8.62 IL1A TLR9

Sources for Corneal Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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