Aliases & Classifications for Corneal Edema

MalaCards integrated aliases for Corneal Edema:

Name: Corneal Edema 12 44 15 17 72
Corneal Oedema 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11030
ICD9CM 35 371.2 371.20
MeSH 44 D015715
NCIt 50 C50508
SNOMED-CT 68 27194006
ICD10 33 H18.20
UMLS 72 C0010037

Summaries for Corneal Edema

MalaCards based summary : Corneal Edema, also known as corneal oedema, is related to glaucoma 1, open angle, a and primary congenital glaucoma, and has symptoms including edema and swelling of eye. An important gene associated with Corneal Edema is CYP1B1 (Cytochrome P450 Family 1 Subfamily B Member 1), and among its related pathways/superpathways are Degradation of the extracellular matrix and IL-17 Family Signaling Pathways. The drugs Hyaluronic acid and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include endothelial, eye and testes, and related phenotype is vision/eye.

Related Diseases for Corneal Edema

Diseases in the Corneal Edema family:

Secondary Corneal Edema

Diseases related to Corneal Edema via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 151)
# Related Disease Score Top Affiliating Genes
1 glaucoma 1, open angle, a 32.7 MYOC CYP1B1
2 primary congenital glaucoma 32.4 TEK MYOC LTBP2 CYP1B1
3 fuchs' endothelial dystrophy 31.9 SLC4A11 FBXO7 COL8A2
4 corneal dystrophy, posterior polymorphous, 1 31.6 SLC4A11 GRHL2 COL8A2
5 glaucoma 3, primary congenital, a 31.6 TEK MYOC LTBP2 FBXO7 CYP1B1
6 corneal endothelial dystrophy 31.4 SLC4A11 FBXO7 COL8A2
7 open-angle glaucoma 30.0 MYOC MMP1 LTBP2 CYP1B1
8 corneal dystrophy 29.8 SLC4A11 GRHL2 COL8A2
9 idiopathic corneal edema 12.5
10 secondary corneal edema 12.4
11 contact lens corneal edema 12.4
12 iridocorneal endothelial syndrome 11.5
13 essential iris atrophy 11.5
14 corneal dystrophy, posterior polymorphous, 4 11.3
15 corneal dystrophy and perceptive deafness 11.2
16 glaucoma 3, primary congenital, d 11.2
17 corneal dystrophy, fuchs endothelial, 4 11.2
18 corneal dystrophy, fuchs endothelial, 5 11.2
19 corneal dystrophy, fuchs endothelial, 6 11.2
20 corneal dystrophy, fuchs endothelial, 8 11.2
21 glaucoma 3, primary congenital, e 11.2
22 cogan-reese syndrome 11.2
23 megalocornea - spherophakia - secondary glaucoma 11.2
24 hydrops, lactic acidosis, and sideroblastic anemia 11.0
25 early-onset glaucoma 10.6 MYOC CYP1B1
26 cataract 10.6
27 excessive tearing 10.4 MYOC LTBP2 CYP1B1
28 keratopathy 10.4
29 periodontitis, chronic 10.4 MMP1 IL1B
30 superior limbic keratoconjunctivitis 10.4 MMP3 MMP1
31 kashin-beck disease 10.4 MMP1 IL1B
32 bullous keratopathy 10.4
33 glaucoma 3, primary infantile, b 10.4 TEK LTBP2 CYP1B1
34 spastic entropion 10.3 MMP3 MMP1
35 macular retinal edema 10.3
36 frozen shoulder 10.3 MMP3 IL1B
37 tendinopathy 10.3 MMP3 MMP1
38 intraocular pressure quantitative trait locus 10.3
39 keratoconus 10.3
40 corneal dystrophy, fuchs endothelial, 1 10.3
41 conjunctivochalasis 10.3 MMP3 MMP1
42 adult astrocytic tumour 10.2 MMP3 MMP1
43 hydrarthrosis 10.2 MMP3 IL1B
44 gingival disease 10.2 MMP1 IL1B
45 hydrophthalmos 10.2 LTBP2 FBXO7 CYP1B1
46 keratitis, hereditary 10.2
47 myopia 10.2
48 pulpitis 10.2 MMP1 IL1B
49 epidermolysis bullosa dystrophica 10.2 MMP3 MMP1
50 adamantinoma of long bones 10.2 MYOC MMP1 CYP1B1

Comorbidity relations with Corneal Edema via Phenotypic Disease Network (PDN):


Bullous Keratopathy Corneal Endothelial Dystrophy

Graphical network of the top 20 diseases related to Corneal Edema:



Diseases related to Corneal Edema

Symptoms & Phenotypes for Corneal Edema

UMLS symptoms related to Corneal Edema:


edema, swelling of eye

MGI Mouse Phenotypes related to Corneal Edema:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 9.17 COL8A2 CYP1B1 GRHL2 LTBP2 MYOC SLC4A11

Drugs & Therapeutics for Corneal Edema

Drugs for Corneal Edema (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 131)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741
2
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
3
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
4
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
5
Difluprednate Approved Phase 4 23674-86-4 443936
6
Fluprednisolone Approved Phase 4 53-34-9
7
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
8
Loteprednol Approved, Experimental Phase 4 129260-79-3, 82034-46-6 444025 9865442
9
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
10
Povidone Approved Phase 4 9003-39-8
11
Povidone-iodine Approved Phase 4 25655-41-8
12
Iodine Approved, Investigational Phase 4 7553-56-2 807
13
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
14 Adjuvants, Immunologic Phase 4
15 Immunologic Factors Phase 4
16 Protective Agents Phase 4
17 Viscosupplements Phase 4
18 Anti-Inflammatory Agents Phase 4
19 Neuroprotective Agents Phase 4
20 Methylprednisolone Acetate Phase 4
21 Peripheral Nervous System Agents Phase 4
22 Prednisolone acetate Phase 4
23 Anti-Allergic Agents Phase 4
24 Micronutrients Phase 4
25 Trace Elements Phase 4
26 Nutrients Phase 4
27 Anti-Infective Agents, Local Phase 4
28 Benzalkonium Compounds Phase 4
29 Analgesics Phase 4
30 Cyclooxygenase Inhibitors Phase 4
31 Anti-Inflammatory Agents, Non-Steroidal Phase 4
32 Analgesics, Non-Narcotic Phase 4
33 Ketorolac Tromethamine Phase 4
34 Antirheumatic Agents Phase 4
35 cadexomer iodine Phase 4
36 Plasma Substitutes Phase 4
37 Blood Substitutes Phase 4
38 Pharmaceutical Solutions Phase 4
39 Ophthalmic Solutions Phase 4
40
Timolol Approved Phase 3 26839-75-8 33624 5478
41
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
42
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
43
Acyclovir Approved Phase 3 59277-89-3 2022
44
Netilmicin Approved, Investigational Phase 3 56391-56-1 441306 6857423
45
Bromfenac Approved Phase 3 91714-94-2 60726
46
Moxifloxacin Approved, Investigational Phase 3 354812-41-2, 151096-09-2 152946
47
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
48
Norgestimate Approved, Investigational Phase 3 35189-28-7 6540478
49
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
50
Polyestradiol phosphate Approved Phase 3 28014-46-2

Interventional clinical trials:

(show top 50) (show all 60)
# Name Status NCT ID Phase Drugs
1 Intraindividual Randomized Clinical Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2% in Phacoemulsification Completed NCT01387620 Phase 4 Hyaluronic Acid and hydroxypropylmethylcellulose
2 A Randomized, Masked Multi-center Safety & Efficacy Study of the Effects of Preoperative & Postoperative Cataract Surgery Use of Difluprednate Ophthalmic Emulsion, 0.05% Compared to Prednisolone Acetate Ophthalmic Suspension 1% on Visual Acuity & Corneal Edema. Completed NCT01244334 Phase 4 Difluprednate ophthalmic emulsion 0.05%;Prednisolone acetate 1%
3 Prospective, Randomized Comparison of Corticosteroid Dosing Regimens Following Endothelial Keratoplasty Completed NCT01853696 Phase 4 loteprednol etabonate;prednisolone acetate 1%
4 Efficacy and Tolerability of Preservative-free 0.0015% Tafluprost in Glaucoma Patients Completed NCT03104621 Phase 4 Benzalkonium chloride (BAK);0.0015% tafluprost
5 Protein Profile of Immunoregulatory Factors in Diabetic Cataract Completed NCT01832311 Phase 4 Ketorolac
6 Prospective, Randomized, Double-blind Comparison of 5 % Against 1.25 % Povidone-iodine Solution as Preoperative Antisepsis for Strabismus Surgery in Young Children Completed NCT00461656 Phase 4 Preoperative conjunctival irrigation with 5% or 1.25% PI
7 A Pilot Study For Efficacy And Safety Of Glanatec® Opthalmic Solution 0.4% On Corneal Edema And Endothelial Cell Counts In Subjects With Fuchs Endothelial Dystrophy Undergoing Descemet Stripping Without Endothelial Keratoplasty Recruiting NCT03249337 Phase 4 Ripasudil hydrochloride hydrate 0.4% ophthalmic solution
8 Phase 3 Study of Brimonidine Tartrate Drops Efficacy in Reducing Post Operative Corneal Edema After Cataract Surgery Unknown status NCT00800423 Phase 3 Brimonidine Tartrate 0.2%;Timolol maleate 0.5%
9 Assessment of Clinical Efficacy of 1% Prednisolone Acetate (Ster ®), Produced by união química, Compared to 1% Prednisolone Acetate (Pred ® Fort), Produced by Allergan, in the Control of Postoperative Inflammation in Cataract Surgery. Unknown status NCT01227876 Phase 3 Ster;Pred Fort
10 The Berkeley Orthokeratology Study Completed NCT00000123 Phase 3
11 Herpetic Eye Disease Study (HEDS) II Completed NCT00000139 Phase 3 Acyclovir
12 A Prospective, Multi-center, Controlled, Double-blind Study to Evaluate the Efficacy and Tolerability of a Steroid/Antibiotic Associated Treatment Following Cataract Extraction by Means of Phaco-emulsification Completed NCT02973880 Phase 3 NETILDEX™ ophthalmic gel;NETILDEX™ eye drops solution
13 Prospective Randomized Study to Determine Whether Use of Rhopressa™ Can Ameliorate Corneal Edema Associated With Fuchs Dystrophy Recruiting NCT04051463 Phase 2, Phase 3 Netarsudil Ophthalmic Solution;Placebo
14 Use of Intracameral Moxifloxacin for the Prevention of Acute Endophthalmitis Following Cataract Surgery: a Controlled and Randomized Clinical Trial Terminated NCT02770729 Phase 3 Moxifloxacin;No injection of moxifloxacin
15 PART A: A PROSPECTIVE, RANDOMIZED, DOUBLE-MASKED, VEHICLE CONTROLLED, PAIRED-EYE PHASE 1/2 CLINICAL STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND EFFICACY OF ELAMIPRETIDE TOPICAL OPHTHALMIC SOLUTION IN SUBJECTS WITH FCED PRESENTING WITH MILD TO MODERATE CORNEAL EDEMA PART B: A PROSPECTIVE, RANDOMIZED, DOUBLE-MASKED, VEHICLE CONTROLLED, PHASE 1/2 CLINICAL STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND EFFICACY OF ELAMIPRETIDE TOPICAL OPHTHALMIC SOLUTION IN SUBJECTS WITH FCED PRESENTING WITH MILD TO MODERATE CORNEAL EDEMA Completed NCT02653391 Phase 1, Phase 2 Elamipretide 1.0% Ophthalmic Solution;Elamipretide 3.0% Ophthalmic Solution
16 Avastin as an Adjunct to Diode Laser Cyclophotoablation in the Treatment of Neovascular Glaucoma Completed NCT01051583 Phase 2
17 Comparative Analysis of Human Amniotic Membrane Graft Versus Contact Lenses in Syntomathic Bullous Keratopathy Completed NCT01926535 Phase 2
18 Prospective, Randomized Crossover Study Of The Hyper-CL™ Lens (Hyper Osmotic Contact Lens) In Subjects Suffering From Corneal Edema Unknown status NCT01890252 saline solution
19 Early Experience With Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) in Patients With Corneal Endothelial Cell Dysfunction: Clinical Outcomes and Diagnostic Imaging Analysis Unknown status NCT00744796
20 Phase 4 Study of Comparison Among 3 Different No-contact Instruments to Valuate Central Corneal Thickness Unknown status NCT01541501
21 Collagen Cross-linking With Riboflavin in a Hypotonic Solution, With UV Light, on Corneas Less Than 400 Microns Thick: an Exploratory Study. Unknown status NCT00890266
22 In Vitro and Clinical Comparison of Corneal Grafts Cultured in Serum Free Medium or Standard Serum Supplemented Medium in Patients With Degeneration of the Corneal Endothelium Unknown status NCT00623584
23 EyeKon Medical, Inc. Capsular Tension Ring Clinical Study Unknown status NCT02332369
24 Corneal Transplantation Guided by OCT RESCAN: Pre-op, Intra-op and Post-op Evaluation Unknown status NCT02736877
25 Cornea Donor Study Unknown status NCT00006411
26 The Variation of the Intraocular Pressure Measured by Different Tonometers in Patients With Clinical Corneal Edema Completed NCT01998568
27 Liquefaction Versus Torsional ip. A Comparative Study on Endothelial Cells, Corneal Edema and Corneal Sensitivity Completed NCT01480557
28 Prospective, Randomized Crossover Study of Using the Hyper-CL™ Lens (Hyper Osmotic Contact Lens) in Subjects Suffering From Corneal Edema Completed NCT02660151 Salt solution
29 ODM 5 in the Treatment of Corneal Edematous Fuchs' Endothelial Dystrophy Completed NCT02332109
30 Study of the Effects of Riboflavin/ Ultraviolet-A Corneal Cross-linking Completed NCT01106274
31 Central Corneal Thickness Assessment After Phacoemulsification: Subluxation Versus Divide-and-Conquer Completed NCT03689270
32 Fuchs' Endothelial Dystrophy: Clinical Characteristics, Treatment Outcome, and Pathology Completed NCT01979250
33 Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma Completed NCT01266343
34 Correlation Between Postoperative Central Corneal Thickness and Endothelial Damage After Cataract Surgery by Phacoemulsification Completed NCT03972670
35 A Prospective, Randomized, Single Center Study Evaluating Use of Surgeon- and Eye Bank-prepared Donor Tissue for Descemet's Stripping and Endothelial Keratoplasty, a Type of Cornea Transplant Completed NCT00624221
36 Amniotic Membrane and Anterior Stromal Puncture: a Comparative Study in the Treatment of Symptomatic Bullous Keratopathy Completed NCT00659308
37 Tobramycin 0.3% - Dexamethasone 0.1% Versus Tobramycin 0.3% - Dexamethasone 0.1% Plus Ketorolac Tromethamine 0.5% After Phacoemulsification Surgery. A Randomized Trial Completed NCT00992355 Tobramycin 0.3% - Dexamethasone 0.1%;Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5%
38 Impact of Ophthalmic Surgeon Experience on Early Postoperative Central Corneal Thickness After Cataract Surgery Completed NCT03685825
39 Viscoat Versus Visthesia. A Comparative Study of Post-cataract Endothelial Cell Loss Completed NCT02304861
40 Ketorolac Plus Tobramycin/Dexamethasone vs. Tobramycin/Dexamethasone After Uneventful Phacoemulsification Surgery Completed NCT01103401 Drug: Tobramycin 0.3% - Dexamethasone 0.1%;Drug: Tobramycin-Dexamethasone plus Ketorolac tromethamine
41 Protecting the Corneal Endothelium During Cataract Surgery Using the Anterior Capsule: a Prospective Randomised Double-masked Study Completed NCT03855293
42 Intracameral Use of Triamcinolone and Gatifloxacin Versus Standard Postoperative Steroid and Antibiotic Eye Drops After Cataract Surgery Completed NCT00478764 intraocular triamcinolone and gatifloxicin
43 Amniotic Membrane Transplant in Symptomatic Bullous Keratopathy Patients: Confocal Microscopy & AS-OCT Long Term Results Completed NCT03450954
44 Immediate Anterior Chamber Paracentesis With A 30-Gauge Needle for Acute Primary Angle - Closure Completed NCT01923454 Acetazolamide
45 The SNEC DSAEK EndoGlide Clinical Trial Completed NCT01122043
46 Effect of Fixed Brinzolamide-brimonidine Combination on Intraocular Pressure After Phacoemulsification Completed NCT03494257 Brinzolamide-Brimonidine fixed combination
47 Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma. Completed NCT03166566
48 Effect of Aflibercept on Human Corneal Endothelial Cells in Neovascular Age-Related Macular Degeneration: A Pilot Study Completed NCT03313401 Aflibercept
49 Ahmed Versus Baerveldt Comparison Study Completed NCT00376363
50 Deep Lamellar Endothelial Keratoplasty as Surgical Treatment for Corneal Endothelial Decompensation Completed NCT00346138

Search NIH Clinical Center for Corneal Edema

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Sodium chloride
Sodium Chloride
SODIUM CHLORIDE 0.9% PROCESSING SOLN
SODIUM CHLORIDE GRANULES

Cochrane evidence based reviews: corneal edema

Genetic Tests for Corneal Edema

Anatomical Context for Corneal Edema

MalaCards organs/tissues related to Corneal Edema:

41
Endothelial, Eye, Testes, Liver, Retina, T Cells, Brain

Publications for Corneal Edema

Articles related to Corneal Edema:

(show top 50) (show all 2599)
# Title Authors PMID Year
1
Prelamellar Dissection Donor Corneal Thickness Is Associated With Descemet Stripping Automated Endothelial Keratoplasty Operative Complications in the Cornea Preservation Time Study. 38
31180926 2019
2
Ocular coherence tomography for the diagnosis of Descemet's detachment after deep sclerectomy and resolution after intracameral air injection. 38
31388603 2019
3
Combined Pupilloplasty and Retropupillary Iris-Claw Intraocular Lens Implantation with DSAEK in a Patient with Traumatic Iridoplegia, Aphakia and Corneal Decompensation. 38
31317508 2019
4
Postoperative Endothelial Cell Density Is Associated with Late Endothelial Graft Failure after Descemet Stripping Automated Endothelial Keratoplasty. 38
30790587 2019
5
Corneal Edema Associated With Systemic Dopaminergic Agents. 38
30950895 2019
6
Unilateral acute hydrops in a child with bilateral microcornea and iridofundal coloboma. 38
31332140 2019
7
Antenatal Findings of Keratitis-Ichthyosis-Deafness Syndrome. 38
31421982 2019
8
Diurnal variation in corneal edema in Fuchs' Endothelial Corneal Dystrophy. 38
31415734 2019
9
Ocular Glands Become Infected Secondarily to Infectious Keratitis and Play a Role in Corneal Resistance to Infection. 38
31167909 2019
10
Protective Action of Linear Polyethylenimine against Staphylococcus aureus Colonization and Exaggerated Inflammation in Vitro and in Vivo. 38
31099239 2019
11
Indications and Outcomes for the Removal of Intraocular Lens Implants in a Retinal Surgery Practice. 38
31415697 2019
12
Effects of scleral-lens oxygen transmissibility on corneal thickness: A pilot study. 38
30995970 2019
13
Intra and post-operative complications observed with femtosecond laser-assisted cataract surgery versus conventional phacoemulsification surgery: a systematic review and meta-analysis. 38
31399070 2019
14
Biophysical and microstructural changes of swelling cornea caused by endothelial cells damage. 38
31424248 2019
15
Microscope-Integrated Optical Coherence Tomography-Guided Drainage of Acute Corneal Hydrops in Keratoconus Combined With Suturing and Gas-Aided Reattachment of Descemet Membrane. 38
31276463 2019
16
Corneal Endothelial Cell Loss and Morphometric Changes 5 Years after Phacoemulsification With or Without CyPass Micro-Stent. 38
31377278 2019
17
Long-term (≥10 years) results of corneal endothelial cell loss after cataract surgery. 38
31358141 2019
18
Treatment of Severe Keratoconus Hydrops With Intracameral Platelet-Rich Plasma Injection. 38
31335522 2019
19
Endothelial keratoplasty for corneal endothelial dystrophy in a dog. 38
30972947 2019
20
Corneal collagen cross-linking following superficial keratectomy as treatment for corneal endothelial cell dystrophy in dogs: Preliminary clinical study. 38
30109755 2019
21
Reliability of the Evidence Addressing Treatment of Corneal Diseases: A Summary of Systematic Reviews. 38
31070698 2019
22
Management of Nocardia Interface Keratitis After Descemet Membrane Endothelial Keratoplasty. 38
31306288 2019
23
Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics. 38
31302714 2019
24
Evaluation of complications and visual outcome in various nucleus delivery techniques of manual small incision cataract surgery. 38
31238414 2019
25
Treatment of chronic and extreme ocular hypotension following glaucoma surgery with intraocular platelet-rich plasma: A case report. 38
30295074 2019
26
ANTERIOR MIGRATION OF INTRAVITREAL FLUOCINOLONE ACETONIDE IMPLANTS: A CASE REPORT. 38
31339874 2019
27
Acute angle-closure glaucoma with choroidal effusion revealing a hantavirus infection: Description of ultrasound biomicroscopy imagery and optical coherence tomography Visante. 38
31256684 2019
28
Toxic anterior segment syndrome: A review. 38
30703402 2019
29
[Muraine sutures accelerate healing of corneal hydrops in acute keratotorus]. 38
30229285 2019
30
Effect of immediate postoperative intracameral tissue plasminogen activator (tPA) on anterior chamber fibrin formation in dogs undergoing phacoemulsification. 38
30773778 2019
31
Long-term outcome of scleral-fixated intraocular lens implantation without conjunctival peritomies and sclerotomy in ocular trauma patients. 38
31357978 2019
32
Effect of Graft Attachment Status and Intraocular Pressure on Descemet Stripping Automated Endothelial Keratoplasty Outcomes in the Cornea Preservation Time Study. 38
30849341 2019
33
Corneal Endotheliitis as a Presentation of Acanthamoeba Keratitis. 38
31219868 2019
34
High rate of recurrence of herpes zoster-related ocular disease after phacoemulsification cataract surgery. 38
30954337 2019
35
Hybrid clear corneal micro-incision surgical technique for stage 5 retinopathy of prematurity. 38
31124519 2019
36
Extrarenal Signs of Proximal Renal Tubular Acidosis Persist in Nonacidemic Nbce1b/c-Null Mice. 38
31040187 2019
37
[Endogenous Klebsiella pneumoniae endophthalmitis associated with Klebsiella pneumoniae pneumonia: 3 cases report and literature review]. 38
31189230 2019
38
Optical Coherence Tomography Assessment of the Cornea During Corneal Swelling: Should the Term "Descemet Membrane Folds" Be Reconsidered? 38
30844840 2019
39
Femtosecond Laser-Assisted Keratolimbal Allograft Transplantation for the Treatment of Total Limbal Stem Cell Deficiency. 38
31259860 2019
40
A Review of Corneal Endotheliitis and Endotheliopathy: Differential Diagnosis, Evaluation, and Treatment. 38
30859513 2019
41
Utility of digitally assisted vitreoretinal surgery systems (DAVS) for high-volume vitreoretinal surgery centre: a pilot study. 38
31177188 2019
42
Magnetic Human Corneal Endothelial Cell Transplant: Delivery, Retention, and Short-Term Efficacy. 38
31158276 2019
43
Comparative analysis of intravitreal triamcinolone acetonide-moxifloxacin versus standard perioperative eyedrops in cataract surgery. 38
30850125 2019
44
[The effectiveness and safety of topical 0.1% tacrolimus after high-risk penetrating keratoplasty]. 38
31189271 2019
45
Ammonia sensitive SLC4A11 mitochondrial uncoupling reduces glutamine induced oxidative stress. 38
31254733 2019
46
Cataract surgery outcomes in eyes with chorioretinal coloboma. 38
31030778 2019
47
Keratometric, Pachymetric, and Surface Elevation Characterization of Corneas With Fuchs Endothelial Corneal Dystrophy Treated With DMEK. 38
30681522 2019
48
Recurrence of herpes simplex virus endotheliitis in a Descemet membrane endothelial keratoplasty graft: mimicking fungal interface infection. 38
31064790 2019
49
Laser scanning in vivo confocal microscopic characterization of equine immune-mediated keratitis. 38
31050168 2019
50
Cucurbita argyrosperma Seed Extracts Attenuate Angiogenesis in a Corneal Chemical Burn Model. 38
31137826 2019

Variations for Corneal Edema

Expression for Corneal Edema

Search GEO for disease gene expression data for Corneal Edema.

Pathways for Corneal Edema

GO Terms for Corneal Edema

Cellular components related to Corneal Edema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.5 TEK MYOC MMP3 MMP1 LTBP2 IL1B
2 extracellular matrix GO:0031012 8.92 MMP3 MMP1 LTBP2 COL8A2

Biological processes related to Corneal Edema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.61 TEK MMP1 IL1B
2 collagen catabolic process GO:0030574 9.46 MMP3 MMP1
3 positive regulation of vascular endothelial growth factor production GO:0010575 9.37 IL1B CYP1B1
4 positive regulation of angiogenesis GO:0045766 9.33 TEK IL1B CYP1B1
5 positive regulation of focal adhesion assembly GO:0051894 9.32 TEK MYOC
6 positive regulation of interleukin-6 secretion GO:2000778 9.26 IL1B DHX9
7 response to hypoxia GO:0001666 9.1 TEK
8 positive regulation of protein oligomerization GO:0032461 8.96 MMP3 MMP1
9 regulation of defense response to virus by host GO:0050691 8.62 IL1B DHX9

Sources for Corneal Edema

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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44 MeSH
45 MESH via Orphanet
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49 NCI
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54 NINDS
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
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73 UMLS via Orphanet
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