Aliases & Classifications for Corneal Edema

MalaCards integrated aliases for Corneal Edema:

Name: Corneal Edema 12 44 15 73
Corneal Oedema 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11030
ICD10 33 H18.20
ICD9CM 35 371.2 371.20
MeSH 44 D015715
NCIt 50 C50508
UMLS 73 C0010037

Summaries for Corneal Edema

MalaCards based summary : Corneal Edema, also known as corneal oedema, is related to glaucoma 1, open angle, a and fuchs' endothelial dystrophy, and has symptoms including edema and swelling of eye. An important gene associated with Corneal Edema is LTBP2 (Latent Transforming Growth Factor Beta Binding Protein 2), and among its related pathways/superpathways are Degradation of the extracellular matrix and IL-17 Family Signaling Pathways. The drugs Methylprednisolone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include endothelial and eye, and related phenotypes are Increased HPV18 LCR reporter activity and Increased HPV18 LCR reporter activity

Related Diseases for Corneal Edema

Diseases in the Corneal Edema family:

Secondary Corneal Edema

Diseases related to Corneal Edema via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 96)
# Related Disease Score Top Affiliating Genes
1 glaucoma 1, open angle, a 31.5 CYP1B1 MYOC OPTN
2 fuchs' endothelial dystrophy 30.7 COL8A2 FBXO7 SLC4A11 TGFBI
3 glaucoma 3, primary congenital, a 30.6 CYP1B1 FBXO7 LTBP2 MYOC OPTN TEK
4 glaucoma 3, primary infantile, b 30.3 CYP1B1 LTBP2 TEK
5 recurrent corneal erosion 30.1 IL1B TGFBI
6 keratoconus 29.3 COL8A2 MMP1 MMP3 TGFBI
7 corneal dystrophy 29.1 COL8A2 SLC4A11 TGFBI
8 corneal endothelial dystrophy 29.1 COL8A2 FBXO7 OPTN SLC4A11 TGFBI
9 primary congenital glaucoma 28.7 CYP1B1 LTBP2 MYOC OPTN TEK
10 idiopathic corneal edema 12.2
11 secondary corneal edema 12.1
12 contact lens corneal edema 12.1
13 iridocorneal endothelial syndrome 11.2
14 essential iris atrophy 11.2
15 corneal dystrophy, posterior polymorphous, 1 10.9
16 corneal dystrophy and perceptive deafness 10.9
17 glaucoma 3, primary congenital, d 10.9
18 corneal dystrophy, fuchs endothelial, 4 10.9
19 corneal dystrophy, fuchs endothelial, 5 10.9
20 corneal dystrophy, fuchs endothelial, 6 10.9
21 corneal dystrophy, fuchs endothelial, 8 10.9
22 glaucoma 3, primary congenital, e 10.9
23 early-onset glaucoma 10.8 CYP1B1 MYOC
24 superior limbic keratoconjunctivitis 10.6 MMP1 MMP3
25 spastic entropion 10.6 MMP1 MMP3
26 frozen shoulder 10.6 IL1B MMP3
27 periodontitis, chronic 10.6 IL1B MMP1
28 adult astrocytic tumour 10.5 MMP1 MMP3
29 conjunctivochalasis 10.5 MMP1 MMP3
30 adenomyosis 10.5 MMP1 MMP3
31 hydrarthrosis 10.5 IL1B MMP3
32 acrofrontofacionasal dysostosis 10.4 CYP1B1 OPTN
33 joint disorders 10.4 IL1B MMP3
34 epidermolysis bullosa dystrophica 10.4 MMP1 MMP3
35 corneal ulcer 10.4 CYP1B1 IL1B MMP3
36 cataract 10.4
37 megalocornea 10.3 LTBP2 OPTN
38 phacogenic glaucoma 10.3 LTBP2 OPTN
39 endotheliitis 10.3
40 pulpitis 10.3 IL1B MMP1
41 gingival disease 10.3 IL1B MMP1
42 corneal dystrophy, posterior polymorphous, 2 10.2 COL8A2 SLC4A11
43 low tension glaucoma 10.2 MYOC OPTN
44 bone deterioration disease 10.2 IL1B MMP1 MMP3
45 bone inflammation disease 10.2 IL1B MMP1 MMP3
46 aortic aneurysm, familial abdominal, 1 10.2 IL1B MMP1 MMP3
47 tendinosis 10.2 MMP1 MMP3
48 synovitis 10.2 IL1B MMP1 MMP3
49 periodontitis 10.2 IL1B MMP1 MMP3
50 periodontal disease 10.2 IL1B MMP1 MMP3

Comorbidity relations with Corneal Edema via Phenotypic Disease Network (PDN):


Bullous Keratopathy Corneal Endothelial Dystrophy

Graphical network of the top 20 diseases related to Corneal Edema:



Diseases related to Corneal Edema

Symptoms & Phenotypes for Corneal Edema

UMLS symptoms related to Corneal Edema:


edema, swelling of eye

GenomeRNAi Phenotypes related to Corneal Edema according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased HPV18 LCR reporter activity GR00197-A-1 9.23 MMP3 TGFBI
2 Increased HPV18 LCR reporter activity GR00197-A-3 9.23 MMP3 TGFBI
3 Increased HPV18 LCR reporter activity GR00197-A-4 9.23 MMP3 TGFBI
4 Increased HPV18 LCR reporter activity GR00197-A-6 9.23 MMP3 TGFBI

MGI Mouse Phenotypes related to Corneal Edema:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 CYP1B1 FBXO7 IL1B MMP1 MMP3 OPTN
2 vision/eye MP:0005391 9.17 COL8A2 CYP1B1 LTBP2 MYOC SLC4A11 TEK

Drugs & Therapeutics for Corneal Edema

Drugs for Corneal Edema (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 135)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
2
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
3
Difluprednate Approved Phase 4 23674-86-4 443936
4
Fluprednisolone Approved Phase 4 53-34-9
5
Hyaluronic acid Approved, Vet_approved Phase 4,Phase 3,Not Applicable 9004-61-9 53477741
6
Loteprednol Approved Phase 4 82034-46-6, 129260-79-3 444025 9865442
7
Ephedrine Approved Phase 4,Phase 3,Not Applicable 299-42-3 9294
8
Pseudoephedrine Approved Phase 4,Phase 3,Not Applicable 90-82-4 7028
9
Iodine Approved, Investigational Phase 4,Not Applicable 7553-56-2 807
10
Povidone Approved Phase 4,Not Applicable 9003-39-8
11
Povidone-iodine Approved Phase 4,Not Applicable 25655-41-8
12
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
13 Estradiol valerate Approved, Investigational, Vet_approved Phase 4 979-32-8
14
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
15
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
16
Nepafenac Approved, Investigational Phase 4 78281-72-8 151075
17
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
18
Polyestradiol phosphate Approved Phase 4 28014-46-2
19
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
20
Vancomycin Approved Phase 4 1404-90-6 441141 14969
21
Ketorolac Approved Phase 4,Not Applicable 74103-06-3, 66635-83-4 3826
22
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
23
Lidocaine Approved, Vet_approved Phase 4,Not Applicable 137-58-6 3676
24
Racepinephrine Approved Phase 4 329-65-7 838
25
Dipivefrin Approved Phase 4,Phase 3,Not Applicable 52365-63-6 3105
26 Antiemetics Phase 4,Phase 3,Not Applicable
27 Anti-Inflammatory Agents Phase 4,Phase 3,Not Applicable
28 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Not Applicable
29 Autonomic Agents Phase 4,Phase 3,Not Applicable
30 Gastrointestinal Agents Phase 4,Phase 3,Not Applicable
31 glucocorticoids Phase 4,Phase 3,Not Applicable
32 Hormone Antagonists Phase 4,Phase 3,Not Applicable
33 Hormones Phase 4,Phase 3,Not Applicable
34 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Not Applicable
35 Methylprednisolone acetate Phase 4,Phase 3
36 Methylprednisolone Hemisuccinate Phase 4,Phase 3
37 Neuroprotective Agents Phase 4,Phase 3
38 Peripheral Nervous System Agents Phase 4,Phase 3,Not Applicable
39 Prednisolone acetate Phase 4,Phase 3
40 Prednisolone hemisuccinate Phase 4,Phase 3
41 Prednisolone phosphate Phase 4,Phase 3
42 Protective Agents Phase 4,Phase 3,Not Applicable
43 Pharmaceutical Solutions Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
44 Anti-Bacterial Agents Phase 4,Phase 3,Not Applicable
45 Antibiotics, Antitubercular Phase 4,Phase 3,Not Applicable
46 Adjuvants, Immunologic Phase 4,Phase 3,Not Applicable
47 Viscosupplements Phase 4,Phase 3,Not Applicable
48 Anti-Allergic Agents Phase 4,Phase 3
49 Ophthalmic Solutions Phase 4,Phase 3,Phase 1,Phase 2
50 Nasal Decongestants Phase 4,Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 69)
# Name Status NCT ID Phase Drugs
1 Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery. Completed NCT01244334 Phase 4 Difluprednate ophthalmic emulsion 0.05%;Prednisolone acetate 1%
2 Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2% Completed NCT01387620 Phase 4 Hyaluronic Acid and hydroxypropylmethylcellulose
3 Comparison of Corticosteroid Dosing Regimens After Endothelial Keratoplasty Completed NCT01853696 Phase 4 loteprednol etabonate;prednisolone acetate 1%
4 A Study to Compare Ocular Safety and Tolerability of Prednisolone Acetate 0.5% Eye Drops Versus Vehicle in Healthy Volunteers Completed NCT00134992 Phase 4 Prednisolone acetate
5 Povidone-iodine Antisepsis for Strabismus Surgery Completed NCT00461656 Phase 4 Preoperative conjunctival irrigation with 5% or 1.25% PI
6 Efficacy and Tolerability of Preservative-free 0.0015% Tafluprost in Glaucoma Patients Completed NCT03104621 Phase 4 Benzalkonium chloride (BAK);0.0015% tafluprost
7 Dropless vs. Standard Drops Contralateral Eye Study Completed NCT02515045 Phase 4 TriMoxiVanc;Moxifloxacin HCl 0.5%;Ilevro;Prednisolone acetate 1%
8 Protein Profile of Immunoregulatory Factors in Diabetic Cataract Completed NCT01832311 Phase 4 Ketorolac
9 A Study to Compare Ocular Safety and Tolerability of Eye Drops Containing Prednisolone Acetate in Patients With Intraocular Inflammation After Cataract Surgery Completed NCT00170729 Phase 4 Prednisolone acetate
10 DisCoVisc Versus DuoVisc, Healon5 and AmVisc Plus Completed NCT00712244 Phase 4
11 Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract Surgery Completed NCT01297153 Phase 4
12 A Comparison of One-site and Two-site Peribulbar Anaesthesia for Cataract Surgery at Kaduna, Nigeria Completed NCT02150460 Phase 4
13 Intraoperative Floppy Iris Syndrome Completed NCT00711347 Phase 4
14 Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy Recruiting NCT03249337 Phase 4 Ripasudil hydrochloride hydrate 0.4% ophthalmic solution
15 Effect of Topical Brimonidine on Post Cataract Surgery Corneal Edema Unknown status NCT00800423 Phase 3 Brimonidine Tartrate 0.2%;Timolol maleate 0.5%
16 Clinical Efficacy of the Drug Ster® Compared With Predfort® in Control of Postoperative Inflammation in Cataract Surgery Unknown status NCT01227876 Phase 3 Ster;Pred Fort
17 Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy Unknown status NCT02769169 Phase 2, Phase 3 Lucentis® (Raibizumab) double-dose;Lucentis® (Raibizumab) regular-dose
18 The Berkeley Orthokeratology Study Completed NCT00000123 Phase 3
19 DisCoVisc Comparative Evaluation Completed NCT00732225 Phase 3
20 Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers Completed NCT00889252 Phase 3
21 Study to Evaluate the Safety for the Treatment of Inflammation Associated With Cataract Surgery Completed NCT02547623 Phase 3 Dexamethasone;Prednisolone
22 Safety Study of a Contact Lens With Ketotifen in Healthy, Normal Volunteers Completed NCT00569777 Phase 3
23 ReSure Sealant Pivotal Study Completed NCT01498224 Phase 3
24 0.3% Sodium Hyaluronate Eye Drop to Prevent Recurrent Corneal Epithelium Exfoliation Recruiting NCT03000556 Phase 3 0.3% Sodium Hyaluronate Eye Drop
25 Clinical Study to Evaluate the Efficacy and Tolerability of an Anti-inflammatory/Antibiotic Treatment Following Ocular Cataract Extraction Not yet recruiting NCT02973880 Phase 3 NETILDEX™ ophthalmic gel;NETILDEX™ eye drops solution
26 Amniotic Membrane Graft In Syntomathic Bullous Keratopathy Completed NCT01926535 Phase 2
27 A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED) Active, not recruiting NCT02653391 Phase 1, Phase 2 Elamipretide 1.0% Ophthalmic Solution;Elamipretide 3.0% Ophthalmic Solution
28 Biodegradable Synthetic Scaffold as a Substitute for hAM in Limbal Epithelial Cells Transplant in LSCD Patients Unknown status NCT02568527 Phase 1
29 Hyper-CL™ Lens (Hyper Osmotic Contact Lens) In Subjects Suffering From Corneal Edema Unknown status NCT01890252 Not Applicable saline solution
30 Early Experience With Descemet's Stripping Automated Endothelial Keratoplasty Unknown status NCT00744796 Not Applicable
31 Cornea Donor Study Unknown status NCT00006411 Not Applicable
32 Comparison of Corneal Grafts Cultured in Serum-free Versus Corneal Grafts Cultured in Serum Supplemented Culture Media Unknown status NCT00623584 Not Applicable
33 Safety and Surgical Performance Study of Aurosleek Surgical Blades Unknown status NCT01763593
34 Corneal Transplantation Guided by OCT RESCAN Unknown status NCT02736877 Not Applicable
35 The Intraocular Pressure Measured by Different Tonometers in Corneal Edema Completed NCT01998568
36 Aqualase Versus Torsional ip. A Study on Endothelial Cells, Corneal Edema and Corneal Sensitivity Completed NCT01480557 Not Applicable
37 A Comparison Between Full Thickness and Partial Thickness Corneal Transplantation for Corneal Edema Completed NCT00346138 Not Applicable
38 ODM 5 in the Treatment of Corneal Edematous Fuchs' Endothelial Dystrophy Completed NCT02332109
39 Viscoat Versus Visthesia. A Comparative Study of Post-cataract Endothelial Cell Loss Completed NCT02304861 Not Applicable
40 Ketorolac Plus Tobramycin/Dexamethasone Versus Tobramycin/Dexamethasone After Uneventful Phacoemulsification Surgery Completed NCT01103401 Not Applicable Drug: Tobramycin 0.3% - Dexamethasone 0.1%;Drug: Tobramycin-Dexamethasone plus Ketorolac tromethamine
41 Study of Eye Bank Pre-cut Donor Grafts for Endothelial Keratoplasty Completed NCT00624221 Not Applicable
42 Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma. Completed NCT03166566 Not Applicable
43 Endoscopic Goniotomy for Infantile Glaucoma Completed NCT00338533 Not Applicable
44 Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma Completed NCT01266343
45 Ahmed Versus Baerveldt Comparison Study Completed NCT00376363 Not Applicable
46 Efficacy of FLACS USFREE Compared to Traditional Surgery Using Ultrasound. Completed NCT03050008 Not Applicable
47 Tobramycin-Dexamethasone Versus Tobramycin-Dexamethasone Plus Ketorolac After Phacoemulsification Surgery Completed NCT00992355 Not Applicable Tobramycin 0.3% - Dexamethasone 0.1%;Tobramycin 0.3% - Dexamethasone 0.1% plus Ketorolac tromethamine 0.5%
48 Comparison of Two Phacoemulsification-methods: HF EasyTip 2.2mm vs. HF EasyTip 2.8mm Completed NCT01936740 Not Applicable
49 Comparison of Two Phacoemulsification-methods: EasyTip 2.2mm vs. Infusion Assisted EasyTip 2.2mm Completed NCT01936727 Not Applicable
50 Comparison of Two Phacoemulsification-methods: Low Fluidic EasyTip 2.2mm vs. High Fluidic EasyTip 2.2mm Completed NCT01936714 Not Applicable

Search NIH Clinical Center for Corneal Edema

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: corneal edema

Genetic Tests for Corneal Edema

Anatomical Context for Corneal Edema

MalaCards organs/tissues related to Corneal Edema:

41
Endothelial, Eye

Publications for Corneal Edema

Articles related to Corneal Edema:

(show top 50) (show all 267)
# Title Authors Year
1
Ultramarathon-Induced Bilateral Corneal Edema: A Case Report and a Review of the Literature. ( 29536349 )
2018
2
A microinvasive technique for management of corneal edema secondary to glaucoma drainage device tube-corneal touch. ( 29786005 )
2018
3
Effects of Scleral-lens Tear Clearance on Corneal Edema and Post-lens Tear Dynamics: A Pilot Study. ( 29787488 )
2018
4
Amantadine-Induced Corneal Edema in a Pediatric Neuro-Oncology Patient: A Case Report. ( 29550414 )
2018
5
Delayed transient corneal edema after intravitreal injection of ocriplasmin. ( 29631850 )
2018
6
Atypical Presentation of Iridocorneal Endothelial Syndrome With Band Keratopathy but No Corneal Edema Managed With Descemet Membrane Endothelial Keratoplasty. ( 29668572 )
2018
7
Central corneal thickness determination in corneal edema. ( 28299437 )
2017
8
Localized Trichiasis Causing Focal Full-Thickness Corneal Edema, Endothelial Cell Loss, and Corneal Scarring Requiring Penetrating Keratoplasty. ( 29422758 )
2017
9
Corneal edema with a systemic epidermal growth factor receptor inhibitor. ( 28576229 )
2017
10
Author reply: central corneal thickness determination in corneal edema. ( 28331997 )
2017
11
Resolution of Chronic Corneal Edema After Surgical Treatment for Ocular Hypotony. ( 28234683 )
2017
12
Transient Ingrowth of Lymphatic Vessels into the Physiologically Avascular Cornea Regulates Corneal Edema and Transparency. ( 28775329 )
2017
13
Extensive bilateral corneal edema 6A weeks after cataract surgery: Keratopathy due to Asclepias physocarpa: a case report. ( 28100180 )
2017
14
Corneal edema after phacoemulsification. ( 29208818 )
2017
15
Corneal edema and keratitis following selective laser trabeculoplasty. ( 29260056 )
2017
16
Performing Reliable Lens Capsulotomy in the Presence of Corneal Edema With a Femtosecond Laser. ( 28873174 )
2017
17
Corneal edema in four horses treated with a superficial keratectomy and Gundersen inlay flap. ( 26778407 )
2016
18
Methylene blue-related corneal edema and iris discoloration. ( 27224079 )
2016
19
Coenzyme Q10 in the Treatment of Corneal Edema in Kearns-Sayre: Is There an Application in Fuchs Endothelial Corneal Dystrophy? ( 27442316 )
2016
20
UUnilateral corneal edema caused by a hidden foreign body. ( 27443601 )
2016
21
Persistent Corneal Edema Associated With Subconjunctival 5-fluorouracil in an Infant With Primary Congenital Glaucoma. ( 27783089 )
2016
22
Influence of early Descemet stripping endothelial keratoplasty on visual outcomes in pseudophakic corneal edema. ( 27633840 )
2016
23
Amantadine use as a risk factor for corneal edema: a nationwide cohort study in Taiwan. ( 27594137 )
2016
24
Non-Contact and Contact Tonometry in Corneal Edema. ( 26583789 )
2016
25
Bilateral corneal edema associated with amantadine. ( 25991839 )
2015
26
Transient corneal edema is a predictive factor for pseudophakic cystoid macular edema after uncomplicated cataract surgery. ( 25646056 )
2015
27
Pathophysiology of transient corneal edema and pseudophakic cystoid macular edema. ( 26028950 )
2015
28
Oxygen therapy for corneal edema after cataract surgery. ( 26232815 )
2015
29
Larger Descemetorhexis to Improve Graft Adhesion in Descemet Membrane Endothelial Keratoplasty Does Not Cause Postoperative Peripheral Corneal Edema. ( 26217874 )
2015
30
Transient Corneal Edema After Phacoemulsification. ( 26208554 )
2015
31
Transient corneal edema circumscribed to the LASIK flap after uneventful cataract surgery. ( 25677294 )
2015
32
Central corneal thickness determination in corneal edema using ultrasound pachymetry, a Scheimpflug camera, and anterior segment OCT. ( 25896108 )
2015
33
Acute corneal edema with subsequent thinning and hyperopic shift following selective laser trabeculoplasty. ( 25263043 )
2014
34
Simultaneous Surgery for Corneal Edema and Aphakia: DSEK and Placement of a Retropupillary Iris Claw Lens. ( 24322799 )
2014
35
A Surprising Cause for Corneal Edema After Cataract Surgery: A Missed Posterior Chamber Intraocular Lens Haptic Remnant. ( 24506516 )
2014
36
Tonometry in corneal edema after cataract surgery: rebound versus goldmann applanation tonometry. ( 24588266 )
2014
37
Self-limiting corneal edema with multiple parallel lines on the endothelium (SCEMPLE). ( 25192915 )
2014
38
Persistent corneal edema after collagen cross-linking for keratoconus. Reply. ( 23521905 )
2013
39
Corneal edema and cystoid macular edema by nuclear fragments after uneventful phacoemulsification. ( 23769795 )
2013
40
Amantadine induced corneal edema in a patient with primary progressive freezing of gait. ( 24868424 )
2013
41
Tonometry in corneal edema after cataract surgery: dynamic contour tonometry versus Goldmann applanation tonometry. ( 23662041 )
2013
42
Corneal edema after phacoemulsification surgery in patients with type II diabetes mellitus. ( 24172560 )
2013
43
The impact of corneal edema on intraocular pressure measurements using goldmann applanation tonometry, Tono-Pen XL, iCare, and ORA: an in vitro model. ( 22366704 )
2013
44
Clinical snapshot: Corneal edema in a Tennessee walking horse. ( 23713160 )
2013
45
Persistent corneal edema after collagen cross-linking for keratoconus. ( 23521904 )
2013
46
Liquefaction versus torsional IP: a comparative study on endothelial cells, corneal edema and corneal sensitivity. ( 23095606 )
2013
47
Persistent corneal edema after collagen cross-linking for keratoconus. ( 23394733 )
2013
48
Comparison of outcomes of penetrating keratoplasty versus Descemet's stripping automated endothelial keratoplasty for penetrating keratoplasty graft failure due to corneal edema. ( 22271071 )
2012
49
Improved intraoperative fundus visualization in corneal edema: the Viscoat trick. ( 22198302 )
2012
50
Massive corneal edema treated with corneal cross-linking. ( 22362237 )
2012

Variations for Corneal Edema

Expression for Corneal Edema

Search GEO for disease gene expression data for Corneal Edema.

Pathways for Corneal Edema

GO Terms for Corneal Edema

Cellular components related to Corneal Edema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 COL8A2 IL1B LTBP2 MMP1 MMP3 MYOC
2 extracellular matrix GO:0031012 9.1 COL8A2 LTBP2 MMP1 MMP3 MYOC TGFBI

Biological processes related to Corneal Edema according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 9.61 IL1B MMP1 TEK
2 positive regulation of angiogenesis GO:0045766 9.43 CYP1B1 IL1B TEK
3 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.4 IL1B OPTN
4 positive regulation of vascular endothelial growth factor production GO:0010575 9.37 CYP1B1 IL1B
5 positive regulation of focal adhesion assembly GO:0051894 9.32 MYOC TEK
6 angiogenesis GO:0001525 9.26 COL8A2 CYP1B1 TEK TGFBI
7 positive regulation of protein oligomerization GO:0032461 9.16 MMP1 MMP3
8 collagen catabolic process GO:0030574 8.8 COL8A2 MMP1 MMP3

Sources for Corneal Edema

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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