MCID: CRN006
MIFTS: 32

Coronary Aneurysm

Categories: Cardiovascular diseases

Aliases & Classifications for Coronary Aneurysm

MalaCards integrated aliases for Coronary Aneurysm:

Name: Coronary Aneurysm 12 44 15 73
Arteriovenous Aneurysm of Coronary Vessels 12
Aneurysmal Lesion of Coronary Artery 12
Aneurysm of Coronary Vessels 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3362
ICD10 33 I25.41
ICD9CM 35 414.11
MeSH 44 D003323
SNOMED-CT 68 373139003 50570003
UMLS 73 C0010051

Summaries for Coronary Aneurysm

MalaCards based summary : Coronary Aneurysm, also known as arteriovenous aneurysm of coronary vessels, is related to coronary artery aneurysm and congenital coronary artery aneurysm. An important gene associated with Coronary Aneurysm is TET1 (Tet Methylcytosine Dioxygenase 1). The drugs Aspirin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and kidney.

Related Diseases for Coronary Aneurysm

Diseases related to Coronary Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
# Related Disease Score Top Affiliating Genes
1 coronary artery aneurysm 11.0
2 congenital coronary artery aneurysm 11.0
3 aneurysm 10.8
4 kawasaki disease 10.5
5 myocardial infarction 10.3
6 acute myocardial infarction 10.2
7 thrombosis 10.2
8 ischemia 10.0
9 systemic lupus erythematosus 9.9
10 polyarteritis nodosa, childhood-onset 9.9
11 lupus erythematosus 9.9
12 polyarteritis nodosa 9.9
13 supravalvular aortic stenosis 9.7
14 arteriovenous fistula 9.7
15 atrial fibrillation 9.7
16 hemopericardium 9.7
17 churg-strauss syndrome 9.7
18 kidney disease 9.7
19 hypereosinophilic syndrome 9.7
20 polycystic kidney disease 9.7
21 allergic angiitis 9.7
22 coronary arterial fistulas 9.7
23 cardiac conduction defect 9.6
24 fibromuscular dysplasia 9.6
25 hypercholesterolemia, familial 9.6
26 marfan syndrome 9.6
27 neurofibromatosis, type i 9.6
28 neurofibromatosis, type iv, of riccardi 9.6
29 rheumatoid arthritis 9.6
30 melioidosis 9.6
31 arthritis 9.6
32 intracranial aneurysm 9.6
33 cardiac tamponade 9.6
34 lyme disease 9.6
35 pericardial effusion 9.6
36 coronary thrombosis 9.6
37 pericarditis 9.6
38 coronary stenosis 9.6
39 pneumonia 9.6
40 silent myocardial infarction 9.6
41 acquired immunodeficiency syndrome 9.6
42 mediastinitis 9.6
43 autosomal dominant polycystic kidney disease 9.6
44 aortic coarctation 9.6
45 chronic active epstein-barr virus infection 9.6
46 microscopic polyangiitis 9.6
47 syncope 9.6
48 endotheliitis 9.6
49 heart aneurysm 6.8 CA8 CLMP IFNAR2 LDB3 TET1 UPK2

Graphical network of the top 20 diseases related to Coronary Aneurysm:



Diseases related to Coronary Aneurysm

Symptoms & Phenotypes for Coronary Aneurysm

Drugs & Therapeutics for Coronary Aneurysm

Drugs for Coronary Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 49)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
2
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
3
Ticlopidine Approved Phase 4 55142-85-3 5472
4 Antirheumatic Agents Phase 4,Phase 2
5 Analgesics Phase 4
6 Analgesics, Non-Narcotic Phase 4
7 Anti-Inflammatory Agents Phase 4
8 Anti-Inflammatory Agents, Non-Steroidal Phase 4
9 Antipyretics Phase 4
10 Cyclooxygenase Inhibitors Phase 4
11 Cytochrome P-450 Enzyme Inhibitors Phase 4
12 Fibrinolytic Agents Phase 4
13 Neurotransmitter Agents Phase 4
14 Peripheral Nervous System Agents Phase 4
15 Platelet Aggregation Inhibitors Phase 4
16 Purinergic P2 Receptor Antagonists Phase 4
17 Purinergic P2Y Receptor Antagonists Phase 4
18
Paclitaxel Approved, Vet_approved Phase 2, Phase 3,Phase 3 33069-62-4 36314
19 Albumin-Bound Paclitaxel Phase 2, Phase 3,Phase 3
20 Antimitotic Agents Phase 2, Phase 3,Phase 3
21 Antineoplastic Agents, Phytogenic Phase 2, Phase 3,Phase 3
22
Doxycycline Approved, Investigational, Vet_approved Phase 2 564-25-0 54671203
23
Infliximab Approved Phase 2 170277-31-3
24 Anticholesteremic Agents Phase 2
25 Antimetabolites Phase 2
26 Atorvastatin Calcium Phase 2 134523-03-8
27 Calcium, Dietary Phase 2,Not Applicable
28 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2
29 Hypolipidemic Agents Phase 2
30 Lipid Regulating Agents Phase 2
31 Antibodies Phase 2
32 gamma-Globulins Phase 2
33 Immunoglobulins Phase 2
34 Immunoglobulins, Intravenous Phase 2
35 Interleukin 1 Receptor Antagonist Protein Phase 2
36 Rho(D) Immune Globulin Phase 2
37 Anti-Bacterial Agents Phase 2
38 Anti-Infective Agents Phase 2
39 Antimalarials Phase 2
40 Antiparasitic Agents Phase 2
41 Antiprotozoal Agents Phase 2
42 Dermatologic Agents Phase 2
43 Gastrointestinal Agents Phase 2
44
Diltiazem Approved, Investigational Not Applicable 42399-41-7 39186
45
Adenosine Approved, Investigational Not Applicable 58-61-7 60961
46
Dobutamine Approved Not Applicable 34368-04-2 36811
47 Antihypertensive Agents Not Applicable
48 calcium channel blockers Not Applicable
49 Vasodilator Agents Not Applicable

Interventional clinical trials:

(show all 16)
# Name Status NCT ID Phase Drugs
1 Trial to Assess the Efficacy of Combination Formula of Aspirin Plus Clopidogrel in Patients With Coronary Stent Completed NCT02410083 Phase 4 Clopirin 1;Clopidogrel-Aspirin(co-administration) 1;Clopirin 2;Clopidogrel-Aspirin(co-administration) 2
2 Trial of Pulse Steroid Therapy in Kawasaki Disease--Pediatric Heart Network Completed NCT00132080 Phase 3 Steroids
3 Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo Coronary Lesions Completed NCT00301522 Phase 2, Phase 3
4 Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stent in the Treatment of In-Stent Restenosis Completed NCT00287573 Phase 2, Phase 3
5 Trial of Atorvastatin on the Persistent Coronary Aneurysm in Children With Kawasaki Disease Unknown status NCT02114099 Phase 2 Atorvastatin
6 Anakinra and Kawasaki Disease Unknown status NCT02390596 Phase 2 Anakinra
7 Prevention of Coronary Aneurysms in Kawasaki Syndrome Completed NCT00000520 Phase 2 immunoglobulins, intravenous;aspirin
8 Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease Recruiting NCT01917721 Phase 2 Doxycycline;Standard care
9 Study of Efficacy and Safety of Canakinumab in Pediatric Patients With Kawasaki Disease Withdrawn NCT02980263 Phase 2 Canakinumab
10 Endothelial Function in Patients With Ectatic Compared to Normal Coronary Arteries Unknown status NCT00548457
11 Assessment Of Total Coronary Circulation Time Using TIMI Frame Count Method (TCCT-TIMI) Unknown status NCT02818127 Not Applicable
12 Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method Unknown status NCT02831153 Not Applicable
13 Coronary Artery Aneurysm Registry Completed NCT02563626
14 Effect of Diltiazem on Coronary Artery Ectasia Completed NCT02024919 Not Applicable intracoronary administration of diltiazem;intracoronary injection of 5 mL saline
15 Prevalence and Early Markers of Atherosclerosis in Adults With a History of Kawasaki Disease Completed NCT01440075 Not Applicable
16 Etiology Study of Kawasaki Disease Recruiting NCT00154596

Search NIH Clinical Center for Coronary Aneurysm

Cochrane evidence based reviews: coronary aneurysm

Genetic Tests for Coronary Aneurysm

Anatomical Context for Coronary Aneurysm

MalaCards organs/tissues related to Coronary Aneurysm:

41
Heart, Endothelial, Kidney, Neutrophil, Lymph Node

Publications for Coronary Aneurysm

Articles related to Coronary Aneurysm:

(show top 50) (show all 298)
# Title Authors Year
1
Case Image: Coronary aneurysm causing fistulization and compression of the left atrium. ( 29853704 )
2018
2
Acute myocardial infarction after blunt chest wall trauma with underlying coronary aneurysm: a case report. ( 29914384 )
2018
3
Transcatheter Aortic Valve Replacement Incidentalomas: A Multimodality Imaging Case of Giant Right Coronary Aneurysm. ( 29796318 )
2018
4
Giant coronary aneurysm culprit of an acute coronary syndrome. ( 29317116 )
2018
5
Percutaneous Closure of a Fistulous Giant Coronary Aneurysm. ( 29705160 )
2018
6
Small right ventricular diverticulum mimicking coronary aneurysm. ( 29912444 )
2018
7
Very Late Stent Migration Within a GiantA Coronary Aneurysm in a Patient WithA Kawasaki Disease: Assessment With Multidetector Computed Tomography. ( 28823775 )
2017
8
Importance of detailed distribution of branches in giant coronary aneurysm. ( 28186232 )
2017
9
Coronary aneurysm formation following bare-metal stent implantation: an optical coherence tomography evaluation. ( 28102661 )
2017
10
Coronary Aneurysm Formation After Bioresorbable Vascular Scaffold Implantation Resulting in Acute Myocardial Infarction. ( 28512285 )
2017
11
Extraluminal Migration of a Drug-Eluting Stent Into a Thrombosed Coronary Aneurysm With Preserved Antegrade FlowA in the Right Coronary Artery. ( 28365264 )
2017
12
"Giant within a giant": a case of typical Kawasaki disease with a giant coronary aneurysm and a large coronary thrombus - a rare case report. ( 28835313 )
2017
13
Lesion preparation with cutting balloon angioplasty is associated with coronary aneurysm formation in polylactide bioresorbable vascular scaffold implantation. ( 28760724 )
2017
14
Long-Term Outcome of Kawasaki Disease Complicated by a Large Coronary Aneurysm. ( 28765734 )
2017
15
Giant coronary aneurysm management with Viabahn covered stent. ( 28483590 )
2017
16
Angioscopic observation of an atherosclerotic coronary aneurysm without yellow plaque. ( 28739628 )
2017
17
Long-Term Prognosis for Patients with Kawasaki Disease Complicated by Large Coronary Aneurysm (diameter a8Y6 mm). ( 28765744 )
2017
18
Stenotic false lumen as inflow of coronary aneurysm and full-metal jacket. ( 28688710 )
2017
19
Nationwide Survey of Patients With Giant Coronary Aneurysm Secondary to Kawasaki Disease 1999-2010 in Japan. ( 28855435 )
2017
20
Bioresorbable Vascular Scaffold Coronary Aneurysm and Thrombosis: Farewell to the Current Bioresorbable Vascular Scaffolds? ( 29086732 )
2017
21
Mega-giant coronary aneurysm: antithrombotic therapy is an option. ( 28821483 )
2017
22
Giant coronary aneurysm exposed on routine echocardiogram. ( 29020369 )
2017
23
Retrospective study of the impact of unrecognised Kawasaki disease, coronary aneurysm and ectasia. ( 28818354 )
2017
24
A Loeys-Dietz patient with a transatlantic odyssey: repeated aortic root surgery ending with a huge left main coronary aneurysm. ( 27624358 )
2016
25
Giant Coronary Aneurysms in a one-month-old Infant with Kawasaki Disease. ( 27641973 )
2016
26
A 5-year-old boy with only fever and giant coronary aneurysms: the enigma of Kawasaki disease? ( 27154559 )
2016
27
ST-elevation myocardial infarction in a young adult secondary to giant coronary aneurysm thrombosis: an important sequela of Kawasaki disease and a management challenge. ( 26791126 )
2016
28
Coronary aneurysm without malapposition after bioresorbable vascular scaffold implantation. ( 27173862 )
2016
29
Giant coronary aneurysm in a patient with non-ST myocardial infarction. ( 27044918 )
2016
30
Multiple coronary aneurysms in a young adult with acquired immunodeficiency syndrome. ( 27168940 )
2016
31
Importance of detailed distribution of branches in giant coronary aneurysm. ( 27634923 )
2016
32
Massive left main coronary aneurysm presenting as trepopnoea. ( 27594368 )
2016
33
Bilateral coronary artery fistulas with a giant coronary aneurysm complicated by aneurysm rupture: A case report. ( 27861394 )
2016
34
Kawasaki Disease With Giant Coronary Aneurysms Requiring a Ventricular Assist Device to Separate From Extracorporeal Membrane Oxygenation: Coronary Issues Can Be a Pediatric Problem Too! ( 27310902 )
2016
35
Coronary Stenosis Associated with a Giant Coronary Aneurysm. ( 26626563 )
2016
36
Biovascular scaffolds and reversible coronary aneurysm. ( 27070996 )
2016
37
Corticosteroid Therapy Might be Associated with the Development of Coronary Aneurysm in Children with Kawasaki Disease. ( 27064036 )
2016
38
An unexpected huge coronary aneurysm. ( 27753603 )
2016
39
Managing bioabsorbable vascular scaffold failure: combined scaffold restenosis and late-acquired coronary aneurysm treated with self-expandable stent. ( 25936494 )
2015
40
Giant coronary aneurysm diagnosed as incidental mediastinal mass. ( 25616825 )
2015
41
A giant coronary aneurysm on the right coronary artery in a 16-year-old patient. ( 26574772 )
2015
42
Giant coronary aneurysm caused by Kawasaki disease: consistency between catheter angiography and electrocardiogram gated dual-source computed tomography angiography. ( 26770226 )
2015
43
Giant coronary aneurysm secondary to coronary-atrial fistula. ( 25660938 )
2015
44
Multimodality Imaging of Giant Right Coronary Aneurysm and Postsurgical Coronary Artery Inflammation. ( 26149430 )
2015
45
A giant coronary aneurysm formed after coronary artery bypass grafting. ( 25634861 )
2015
46
Giant right coronary aneurysm untreatable by percutaneous intervention. ( 26481179 )
2015
47
Coronary Aneurysm and Stent Fracture Following Stenting of a Myocaridal Bridge. ( 25573225 )
2015
48
Surgical Resection of a Giant Coronary Aneurysm. ( 26046882 )
2015
49
Intracoronary blood sampling with a microcatheter for the diagnosis of giant infective coronary aneurysm: Melioidosis of coronary artery mycotic aneurysm. ( 25863294 )
2015
50
Acute Myocardial Infarction That Resulted From Poor Adherence to Medical Treatment for Giant Coronary Aneurysm. ( 26155999 )
2015

Variations for Coronary Aneurysm

Expression for Coronary Aneurysm

Search GEO for disease gene expression data for Coronary Aneurysm.

Pathways for Coronary Aneurysm

GO Terms for Coronary Aneurysm

Sources for Coronary Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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