CHDS2
MCID: CRN174
MIFTS: 17

Coronary Heart Disease 2 (CHDS2)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Coronary Heart Disease 2

MalaCards integrated aliases for Coronary Heart Disease 2:

Name: Coronary Heart Disease 2 58 6
Coronary Heart Disease, Susceptibility to, 2 58 13 74
Chds2 58

Classifications:



External Ids:

OMIM 58 608316
UMLS 74 C1842260

Summaries for Coronary Heart Disease 2

MalaCards based summary : Coronary Heart Disease 2, also known as coronary heart disease, susceptibility to, 2, is related to coronary heart disease 1 and heart disease. An important gene associated with Coronary Heart Disease 2 is CHDS2 (Coronary Heart Disease, Susceptibility To, 2). The drugs Calcium and Bone Density Conservation Agents have been mentioned in the context of this disorder. Affiliated tissues include heart and bone.

Description from OMIM: 608316

Related Diseases for Coronary Heart Disease 2

Diseases in the Coronary Heart Disease 1 family:

Coronary Heart Disease 3 Coronary Heart Disease 2
Coronary Heart Disease 4 Coronary Heart Disease 5
Coronary Heart Disease 7 Coronary Heart Disease 8
Coronary Heart Disease 9 Coronary Heart Disease 6

Diseases related to Coronary Heart Disease 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 coronary heart disease 1 9.8
2 heart disease 9.8

Symptoms & Phenotypes for Coronary Heart Disease 2

Clinical features from OMIM:

608316

Drugs & Therapeutics for Coronary Heart Disease 2

Drugs for Coronary Heart Disease 2 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Calcium Approved, Nutraceutical Not Applicable 7440-70-2 271
2 Bone Density Conservation Agents Not Applicable
3 Hormones Not Applicable
4 Calcium, Dietary Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Renal Sympathetic Denervation as Secondary Prevention for Patients After Percutaneous Coronary Intervention. Unknown status NCT01733901 Not Applicable
2 Clinical Evaluation of Magnetic Resonance Imaging in Coronary Heart Disease-2 Completed NCT01664858 Not Applicable
3 Online Study of Individuals With Genetic Changes and Features of Autism: Simons Variation in Individuals Project (Simons VIP) Recruiting NCT01238250

Search NIH Clinical Center for Coronary Heart Disease 2

Genetic Tests for Coronary Heart Disease 2

Anatomical Context for Coronary Heart Disease 2

MalaCards organs/tissues related to Coronary Heart Disease 2:

42
Heart, Bone

Publications for Coronary Heart Disease 2

Articles related to Coronary Heart Disease 2:

# Title Authors Year
1
Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease. ( 25497243 )
2015

Variations for Coronary Heart Disease 2

ClinVar genetic disease variations for Coronary Heart Disease 2:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 IL1B NM_000576.2(IL1B): c.99+383G> C single nucleotide variant not provided rs281864746 GRCh37 Chromosome 2, 113592760: 113592760
2 IL1B NM_000576.2(IL1B): c.99+383G> C single nucleotide variant not provided rs281864746 GRCh38 Chromosome 2, 112835183: 112835183

Expression for Coronary Heart Disease 2

Search GEO for disease gene expression data for Coronary Heart Disease 2.

Pathways for Coronary Heart Disease 2

GO Terms for Coronary Heart Disease 2

Sources for Coronary Heart Disease 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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