CHDS7
MCID: CRN177
MIFTS: 19

Coronary Heart Disease 7 (CHDS7)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Coronary Heart Disease 7

MalaCards integrated aliases for Coronary Heart Disease 7:

Name: Coronary Heart Disease 7 56 73 29 6
Coronary Heart Disease, Susceptibility to, 7 56 13
Chds7 56 73
Heart, Coronary, Disease, Susceptibility to, Type 7 39

Classifications:



External Ids:

OMIM 56 610938
MeSH 43 D003327
MedGen 41 C1970441

Summaries for Coronary Heart Disease 7

UniProtKB/Swiss-Prot : 73 Coronary heart disease 7: A multifactorial disease characterized by an imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow. Decreased capacity of the coronary vessels is often associated with thickening and loss of elasticity of the coronary arteries.

MalaCards based summary : Coronary Heart Disease 7, also known as coronary heart disease, susceptibility to, 7, is related to coronary heart disease 1 and heart disease. An important gene associated with Coronary Heart Disease 7 is CD36 (CD36 Molecule). Affiliated tissues include heart, kidney and testes.

More information from OMIM: 610938

Related Diseases for Coronary Heart Disease 7

Diseases in the Coronary Heart Disease 1 family:

Coronary Heart Disease 3 Coronary Heart Disease 2
Coronary Heart Disease 4 Coronary Heart Disease 5
Coronary Heart Disease 7 Coronary Heart Disease 8
Coronary Heart Disease 9 Coronary Heart Disease 6

Diseases related to Coronary Heart Disease 7 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 coronary heart disease 1 9.9
2 heart disease 9.9

Symptoms & Phenotypes for Coronary Heart Disease 7

Clinical features from OMIM:

610938

Drugs & Therapeutics for Coronary Heart Disease 7

Search Clinical Trials , NIH Clinical Center for Coronary Heart Disease 7

Genetic Tests for Coronary Heart Disease 7

Genetic tests related to Coronary Heart Disease 7:

# Genetic test Affiliating Genes
1 Coronary Heart Disease 7 29 CD36

Anatomical Context for Coronary Heart Disease 7

MalaCards organs/tissues related to Coronary Heart Disease 7:

40
Heart, Kidney, Testes

Publications for Coronary Heart Disease 7

Articles related to Coronary Heart Disease 7:

# Title Authors PMID Year
1
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. 56 6
15282206 2004
2
Cardio-ankle vascular index predicts for the incidence of cardiovascular events in obese patients: a multicenter prospective cohort study (Japan Obesity and Metabolic Syndrome Study: JOMS). 61
26295798 2015
3
Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy. 61
22818936 2012
4
[Combined therapy of membranoproliferative glomerulonephritis in older patients]. 61
23130519 2012
5
Obesity-related changes in high-density lipoprotein metabolism. 61
18388903 2008
6
Red cell shape changes in the blood of people 60 years of age and older imply a role for blood rheology in the aging process. 61
12920351 2003
7
Long-term reproducibility of electrophysiologically guided therapy with sotalol in patients with ventricular tachyarrhythmias. 61
10362204 1999
8
Assessment of long-term risks for living related kidney donors by 24-h blood pressure monitoring and testing for microalbuminuria. 61
9361933 1997
9
[Intravenous fibrinolytic treatment in chronic ischemic heart disease (author's transl)]. 61
7210776 1981

Variations for Coronary Heart Disease 7

ClinVar genetic disease variations for Coronary Heart Disease 7:

6 ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 CD36 NM_001001547.3(CD36):c.429+2T>CSNV Likely pathogenic 417962 rs3211893 7:80290528-80290528 7:80661212-80661212
2 CD36 NM_001001547.3(CD36):c.1254+1G>ASNV Uncertain significance 417926 rs148051111 7:80302726-80302726 7:80673410-80673410
3 CD36 NM_001001547.3(CD36):c.701_701+3dupduplication Likely benign 417963 rs1554343345 7:80293811-80293812 7:80664495-80664496
4 CD36 NM_001001547.3(CD36):c.-184+11225A>GSNV no interpretation for the single variant 487077 rs1984112 7:80242920-80242920 7:80613604-80613604
5 CD36 -31118A-GSNV no interpretation for the single variant 487078
6 CD36 25444G-ASNV no interpretation for the single variant 487079
7 CD36 30294C-GSNV no interpretation for the single variant 487080
8 CD36 27645del/insindel no interpretation for the single variant 487081

Expression for Coronary Heart Disease 7

Search GEO for disease gene expression data for Coronary Heart Disease 7.

Pathways for Coronary Heart Disease 7

GO Terms for Coronary Heart Disease 7

Sources for Coronary Heart Disease 7

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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