CHDS7
MCID: CRN177
MIFTS: 13

Coronary Heart Disease 7 (CHDS7)

Categories: Blood diseases, Genetic diseases

Aliases & Classifications for Coronary Heart Disease 7

MalaCards integrated aliases for Coronary Heart Disease 7:

Name: Coronary Heart Disease 7 58 76 30 6
Coronary Heart Disease, Susceptibility to, 7 58 13
Chds7 58 76
Heart, Coronary, Disease, Susceptibility to, Type 7 41

Classifications:



External Ids:

OMIM 58 610938
MeSH 45 D003327
MedGen 43 C1970441

Summaries for Coronary Heart Disease 7

UniProtKB/Swiss-Prot : 76 Coronary heart disease 7: A multifactorial disease characterized by an imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow. Decreased capacity of the coronary vessels is often associated with thickening and loss of elasticity of the coronary arteries.

MalaCards based summary : Coronary Heart Disease 7, is also known as coronary heart disease, susceptibility to, 7. An important gene associated with Coronary Heart Disease 7 is CD36 (CD36 Molecule). Affiliated tissues include heart.

Description from OMIM: 610938

Related Diseases for Coronary Heart Disease 7

Symptoms & Phenotypes for Coronary Heart Disease 7

Clinical features from OMIM:

610938

Drugs & Therapeutics for Coronary Heart Disease 7

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical and Molecular Study of CHARGE Syndrom Completed NCT03186144 Not Applicable

Search NIH Clinical Center for Coronary Heart Disease 7

Genetic Tests for Coronary Heart Disease 7

Genetic tests related to Coronary Heart Disease 7:

# Genetic test Affiliating Genes
1 Coronary Heart Disease 7 30 CD36

Anatomical Context for Coronary Heart Disease 7

MalaCards organs/tissues related to Coronary Heart Disease 7:

42
Heart

Publications for Coronary Heart Disease 7

Articles related to Coronary Heart Disease 7:

# Title Authors Year
1
A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians. ( 15282206 )
2004

Variations for Coronary Heart Disease 7

ClinVar genetic disease variations for Coronary Heart Disease 7:

6 (show all 12)
# Gene Variation Type Significance SNP ID Assembly Location
1 CD36 NM_001001547.2(CD36): c.429+2T> C single nucleotide variant Likely pathogenic rs3211893 GRCh37 Chromosome 7, 80290528: 80290528
2 CD36 NM_001001547.2(CD36): c.429+2T> C single nucleotide variant Likely pathogenic rs3211893 GRCh38 Chromosome 7, 80661212: 80661212
3 CD36 NM_001001547.2(CD36): c.701_701+3dup duplication Likely benign rs1554343345 GRCh38 Chromosome 7, 80664497: 80664500
4 CD36 NM_001001547.2(CD36): c.701_701+3dup duplication Likely benign rs1554343345 GRCh37 Chromosome 7, 80293813: 80293816
5 CD36 NM_001001547.2(CD36): c.1254+1G> A single nucleotide variant Likely pathogenic rs148051111 GRCh37 Chromosome 7, 80302726: 80302726
6 CD36 NM_001001547.2(CD36): c.1254+1G> A single nucleotide variant Likely pathogenic rs148051111 GRCh38 Chromosome 7, 80673410: 80673410
7 CD36 NM_001001547.2(CD36): c.-184+11225A> G single nucleotide variant no interpretation for the single variant GRCh38 Chromosome 7, 80613604: 80613604
8 CD36 NM_001001547.2(CD36): c.-184+11225A> G single nucleotide variant no interpretation for the single variant GRCh37 Chromosome 7, 80242920: 80242920
9 CD36 -31118A-G single nucleotide variant no interpretation for the single variant
10 CD36 25444G-A single nucleotide variant no interpretation for the single variant
11 CD36 30294C-G single nucleotide variant no interpretation for the single variant
12 CD36 27645del/ins indel no interpretation for the single variant

Expression for Coronary Heart Disease 7

Search GEO for disease gene expression data for Coronary Heart Disease 7.

Pathways for Coronary Heart Disease 7

GO Terms for Coronary Heart Disease 7

Sources for Coronary Heart Disease 7

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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