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MCID: CRN017
MIFTS: 45

Coronary Thrombosis

Categories: Blood diseases, Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Coronary Thrombosis

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MalaCards integrated aliases for Coronary Thrombosis:

Name: Coronary Thrombosis 12 55 44 15 17 72
Coronary Artery Thrombosis 12

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases Blood diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:11847
MeSH 44 D003328
SNOMED-CT 68 66514008
ICD10 33 I21 I22
UMLS 72 C0010072
Sources

Summaries for Coronary Thrombosis

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MalaCards based summary : Coronary Thrombosis, also known as coronary artery thrombosis, is related to angina pectoris and intracranial embolism. An important gene associated with Coronary Thrombosis is PLAT (Plasminogen Activator, Tissue Type), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and ECM-receptor interaction. The drugs Clopidogrel and Ticagrelor have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and neutrophil, and related phenotypes are hematopoietic system and cardiovascular system

Wikipedia : 75 Coronary thrombosis is the formation of a blood clot inside a blood vessel of the heart. This blood clot... more...

Sources

Related Diseases for Coronary Thrombosis

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Diseases related to Coronary Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 232)
# Related Disease Score Top Affiliating Genes
1 angina pectoris 31.0 SERPINC1 PLAT
2 intracranial embolism 30.6 SERPINC1 PLAT
3 subendocardial myocardial infarction 30.4 SERPINE1 SERPINC1
4 heparin-induced thrombocytopenia 30.1 SERPINC1 F3
5 platelet aggregation, spontaneous 30.0 VWF SERPINC1 PLAT
6 thrombocytopenia 29.9 ITGB3 GP1BA F3
7 thrombocytopenic purpura, autoimmune 29.7 ITGB3 GP6 GP1BA
8 protein s deficiency 29.6 SERPINC1 F3
9 thrombophlebitis 29.6 SERPINE1 SERPINC1 PLAT
10 hemophilia 29.5 VWF F3
11 catastrophic antiphospholipid syndrome 29.5 SERPINE1 F3
12 hemophilia b 29.5 SERPINC1 F3
13 hemophilia a 29.4 VWF F3
14 coronary stenosis 29.3 VWF SERPINE1
15 von willebrand's disease 29.1 VWF GP1BA F3
16 carotid artery thrombosis 29.1 SERPINE1 PLAT F3
17 antiphospholipid syndrome 29.1 VWF SERPINC1 PLAT F3
18 intermediate coronary syndrome 29.1 VWF SERPINC1 PLAT P2RY12 F3
19 intracranial thrombosis 29.0 VWF SERPINC1 F3
20 thrombotic thrombocytopenic purpura 29.0 VWF F3
21 hypertension, essential 28.9 VWF SERPINE1 PLAT
22 purpura 28.9 VWF SERPINC1 ITGB3 F3
23 acute myocardial infarction 28.9 VWF SERPINE1 SERPINC1 PLAT F3
24 thrombophilia 28.6 VWF SERPINE1 SERPINC1 F3
25 disseminated intravascular coagulation 28.5 SERPINE1 SERPINC1 PLAT F3
26 pulmonary embolism 28.4 VWF SERPINE1 SERPINC1 PLAT F3
27 thrombophilia due to thrombin defect 28.3 VWF SERPINE1 SERPINC1 PLAT F3
28 essential thrombocythemia 28.1 VWF SERPINE1 ITGB3 GP1BA F3
29 thrombosis 28.1 VWF SERPINE1 SERPINC1 PLAT P2RY12 GP6
30 arteries, anomalies of 27.8 VWF SERPINE1 SERPINC1 PLAT P2RY12 F3
31 heart disease 27.7 VWF SERPINE1 SERPINC1 PLAT F3
32 vascular disease 27.2 VWF SERPINE1 SERPINC1 PLAT ITGB3 GP1BA
33 myocardial infarction 27.0 VWF SERPINE1 SERPINC1 PLAT P2RY12 ITGB3
34 arterial calcification of infancy 11.3
35 posterior myocardial infarction 10.5 SERPINC1 PLAT
36 encephalopathy, familial, with neuroserpin inclusion bodies 10.5 SERPINC1 PLAT
37 fetal and neonatal alloimmune thrombocytopenia 10.5 ITGB3 GP1BA
38 autosomal dominant macrothrombocytopenia 10.5 ITGB3 GP1BA
39 pleuropneumonia 10.5 SERPINC1 PLAT
40 dysfibrinogenemia 10.4 SERPINC1 PLAT
41 myeloproliferative syndrome, transient 10.4 ITGB3 GP1BA
42 clopidogrel resistance 10.4 P2RY12 ITGB3
43 atherosclerosis susceptibility 10.4
44 arteritic anterior ischemic optic neuropathy 10.4 ITGB3 GP1BA
45 eisenmenger syndrome 10.3 VWF PLAT
46 ischemia 10.3
47 acquired von willebrand syndrome 10.3 VWF GP1BA
48 pseudo-von willebrand disease 10.3 VWF GP1BA
49 plasminogen activator inhibitor-1 deficiency 10.3 SERPINE1 PLAT
50 central serous chorioretinopathy 10.3 SERPINE1 PLAT

Graphical network of the top 20 diseases related to Coronary Thrombosis:



Diseases related to Coronary Thrombosis
Sources

Symptoms & Phenotypes for Coronary Thrombosis

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MGI Mouse Phenotypes related to Coronary Thrombosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.96 F3 GP1BA GP6 ITGB3 P2RY12 PLAT
2 cardiovascular system MP:0005385 9.87 F3 ITGB3 PLAT SERPINC1 SERPINE1 SERPINF1
3 homeostasis/metabolism MP:0005376 9.81 F3 GP1BA GP6 ITGB3 P2RY12 PLAT
4 immune system MP:0005387 9.56 F3 GP6 ITGB3 PLAT SERPINC1 SERPINE1
5 vision/eye MP:0005391 9.1 F3 GP6 ITGB3 PLAT SERPINC1 SERPINF1
Sources

Drugs & Therapeutics for Coronary Thrombosis

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Drugs for Coronary Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 70)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clopidogrel Approved Phase 4 113665-84-2, 120202-66-6 60606
2
Ticagrelor Approved Phase 4 274693-27-5 9871419
3
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
4
Sirolimus Approved, Investigational Phase 4 53123-88-9 6436030 5284616 46835353
5
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
6
Everolimus Approved Phase 4 159351-69-6 6442177 70789204
7
Atorvastatin Approved Phase 4 134523-00-5 60823
8
Tirofiban Approved Phase 4 144494-65-5 60947
9 Neurotransmitter Agents Phase 4
10 Purinergic P2Y Receptor Antagonists Phase 4
11 Purinergic P2 Receptor Antagonists Phase 4
12 Neuroprotective Agents Phase 4
13 Respiratory System Agents Phase 4
14 Phosphodiesterase Inhibitors Phase 4
15 Protective Agents Phase 4
16 Anti-Asthmatic Agents Phase 4
17 Autonomic Agents Phase 4
18 Phosphodiesterase 3 Inhibitors Phase 4
19 Bronchodilator Agents Phase 4
20 Antifungal Agents Phase 4
21 Antibiotics, Antitubercular Phase 4
22 Immunosuppressive Agents Phase 4
23 Immunologic Factors Phase 4
24 Lipid Regulating Agents Phase 4
25 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
26 Hypolipidemic Agents Phase 4
27 Anticholesteremic Agents Phase 4
28 Antimetabolites Phase 4
29
tannic acid Approved Phase 3 1401-55-4
30
Chromium Approved Phase 3 7440-47-3 27668
31
Cobalt Approved, Experimental Phase 3 7440-48-4 104729
32
Benzocaine Approved, Investigational Phase 3 94-09-7, 1994-09-7 2337
33
Streptokinase Approved, Investigational Phase 3 9002-01-1
34
Nitroglycerin Approved, Investigational Phase 3 55-63-0 4510
35
Omeprazole Approved, Investigational, Vet_approved Phase 3 73590-58-6 4594
36 Micronutrients Phase 3
37 Nutrients Phase 3
38 Trace Elements Phase 3
39 Vasodilator Agents Phase 3
40 2-(4-(quinolin-2-yl-methoxy)phenyl)-2-cyclopentylacetic acid Phase 3
41 Lipoxygenase Inhibitors Phase 3
42
Iron Approved, Experimental Phase 2 15438-31-0, 7439-89-6 23925 27284
43
Heparin Approved, Investigational Phase 2 9005-49-6 46507594 772
44
Protein C Approved Phase 2
45 Nutmeg Approved Phase 2
46 Parenteral Nutrition Solutions Phase 2
47 Hematinics Phase 2
48 Pharmaceutical Solutions Phase 2
49 Ferrosoferric Oxide Phase 2
50 Thromboplastin Phase 2

Interventional clinical trials:

(show all 46)
# Name Status NCT ID Phase Drugs
1 Effect of aSpirin Versus CilOstazol for Inhibition of Antiplatelet aggRegaTion in Type 2 DM Patients Unknown status NCT02933788 Phase 4 Cilostazol;Acetylsalicylic acid
2 A Clinical Evaluation of Dual Antiplatelet Therapy Duration Following Treatment With the Medtronic Endeavor Zotarolimus-eluting Coronary Stent Unknown status NCT00963781 Phase 4 Reduced duration (6 months) DAPT
3 Comparison of Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI Undergoing PPCI Evaluated by SPECT Unknown status NCT02233790 Phase 4 Ticagrelor;Clopidogrel
4 Effects of Early Atorvastatin Treatment During the Acute Phase of Stroke on Immunoinflammatory Markers and Outcome in Patients With Acute Ischemic Stroke Classified as LAAS According TOAST Classification Completed NCT02225834 Phase 4 Atorvastatin
5 Optical Coherence Tomography Assessment of Gender diVersity In Primary Angioplasty: The OCTAVIA Trial Completed NCT02577965 Phase 4
6 Evaluation of Late Clinical Events After Drug-eluting Versus Bare-metal Stents in Patients at Risk: BAsel Stent Kosten Effektivitäts Trial - PROspective Validation Examination Part II (BASKET-PROVE II) Completed NCT01166685 Phase 4
7 Treatment by Anti GP IIb/IIIa in the Setting of a Strategy of Early Coronarography to Patients With an Acute Coronary Syndrome Without ST Elevation Terminated NCT00445263 Phase 4 TIROFIBAN
8 Comparative Effectiveness of the Eradication of Helicobacter Pylori and an Inhibitor of Pump With Proton Versus Control on the Gastric Lesions Induced by the Aspirin With the Low Dose Among Patients Treated With the Long Course Withdrawn NCT00713947 Phase 4 during one week for the active treatments;Pantoprazole;Placebo Formula 515
9 A Randomized Trial of Bare Metal Stent (Cronus®) - Cobalt Chromium Versus Stent Coating With Sirolimus (DES) Completed NCT01093391 Phase 3
10 Intravenous Streptokinase in Acute Myocardial Infarction Completed NCT00000507 Phase 3 streptokinase
11 Randomized Clinical Trial of Non-Surgical Reperfusion of the Coronary Arteries Completed NCT00000503 Phase 3 nitroglycerin;streptokinase
12 Coronary Angiography in Critically Ill Patients With Type II Myocardial Infarction Not yet recruiting NCT04043091 Phase 3
13 A Randomized, Double-Blind, Placebo-Controlled Study to Examine the Safety and Efficacy of Veliflapon (DG-031) in Reducing the Risk of Acute Cardiovascular Events in African American Patients With Coronary Artery Disease(The LTCAD Study). Suspended NCT00353067 Phase 3 veliflapon (DG-031)
14 A Randomized, Double-Blind, Double-Dummy, Parallel Group, Phase 3 Efficacy and Safety Study of CGT-2168 Compared With Clopidogrel to Reduce Upper Gastrointestinal Events Including Bleeding and Symptomatic Ulcer Disease Terminated NCT00557921 Phase 3 CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin;Plavix (clopidogrel 75 mg) and aspirin
15 ASSESSMENT OF CELLULAR INFLAMMATION FOLLOWING ACUTE MYOCARDIAL INFARCTION Application Of Ultrasmall Superparamagnetic Particles Of Iron Oxide Unknown status NCT01995799 Phase 2
16 A Double-Blind Study of E5555 in Japanese Patients With Acute Coronary Syndrome Completed NCT00619164 Phase 2 E5555;E5555;E5555;Placebo
17 A Randomized, Double-Blind Placebo-Controlled Study to Assess the Safety of Factor VIIa/Tissue Factor Inhibitor, Recombinant Nematode Anticoagulant Protein c2 (rNAPc2), in Subjects With Non-ST-Elevation Acute Coronary Syndromes - ANTHEM (Anticoagulation With rNAPc2 to Help Eliminate MACE)/TIMI 32. Amendment #3 - A Single Arm, Open-Label Study of rNAPc2 With Reduced Doses of Unfractionated Heparin Completed NCT00116012 Phase 2 rNAPc2
18 Evaluation of Neointimal Healing of Endothelial Progenitor Cell Capturing Sirolimus-Eluting (COMBO) Stent by Optical Coherence Tomography: the EGO-COMBO Pilot Study Completed NCT01274234 Phase 1, Phase 2
19 Periprocedural Myocardial Infarction: the Role of Human Neutrophil Peptide-1 to 3 Unknown status NCT02591264
20 Angiographic and Intravascular Ultrasound (IVUS) Follow-up After Simultaneously Implanted Different Drug-eluting Stents in Same Individuals Unknown status NCT00973375
21 Pilot Study Investigating the Use of a Variety of Assays to Detect Individual Response to Antiplatelet Therapy Unknown status NCT00327041
22 Study of ABSORB Stent in Acute Coronary Syndrome Unknown status NCT02071342
23 Platelets Function and Cardiovascular Events in Patients With End Stage Renal Disease Unknown status NCT00407368
24 Does the Human Gut Microbiome Serve as a Novel Personalized Therapeutic Target for Coronary Atherosclerosis? Unknown status NCT03009565
25 Multi-Ethnic Study of Atherosclerosis (MESA) Unknown status NCT00005487
26 Assessment of Coagulation and Thrombocyte Function After Termination of Ticagrelor in Patients Who Have Previously Undergone PCI Procedures and Insertion of Coronary Stents Completed NCT02297971
27 Study of Myeloid-related Protein 8/14 and Additional Biomarkers (Multi Marker Approach) for Early Diagnosis and Risk Stratification in Patients Presenting With Acute Chest Pain at the Emergency Department Completed NCT00657436
28 Xtractâ„¢ Aspiration Catheter Registry Study Completed NCT00349570
29 A Prospective Registry for the Use of CypherTM Sirolimus-Eluting Stents In Patients With Coronary Artery Disease Treated With Percutaneous Coronary Interventions at Scripps Clinic Completed NCT00714623
30 Optical Frequency Domain Imaging-Quantified Intracoronary Thrombus Mass During Primary Percutaneous Coronary Intervention, Its Relationship With Antiplatelet Pretreatment Effect And Its Impact On Myocardial Reperfusion Completed NCT03342521
31 Hs-CRP as Clinical Marker of Inflammatory Atherogenic Dyslipidemia Completed NCT00169871
32 Thrombogenic Factors and Recurrent Coronary Events Completed NCT00005358
33 Optical Coherence Tomography in Patients With Acute Myocardial Infarction and Nonobstructive Coronary Artery Disease: OCT and CMR Study (SOFT-MI) Completed NCT02783963
34 Single-centre, Prospective, Randomised, Placebo-controlled, Parallel-group Design to Determine the Cholesterol-lowering Efficacy of Lactobacillus Plantarum ECGC 13110402 in Normal to Mildly Hypercholesterolaemic Adults Completed NCT03263104
35 Thrombotic, Inflammatory & Gene Markers of CVD in Women Completed NCT00006539
36 Mechanisms of Very Late Bioresorbable Scaffold Thrombosis Assessed by Optical Coherence Tomography: Insights From the International INVEST Registry Completed NCT03180931
37 Prospective Evaluation of Acetyl-Coenzyme A Carboxylase Phosphorylation State in Platelets in Atherothrombotic Coronary Artery Disease. Completed NCT03034148
38 Etiology of Myocardial Injury Following Non-cardiac Surgery - a Prospective Clinical Trial Recruiting NCT03317561
39 Clinical Trial on Safety and Efficacy of Drug-coated Balloon in Treatment of Coronary Bifurcation Lesions Recruiting NCT03223974
40 Assessment of Thrombotic Status in Patients With Acute Coronary Syndrome Recruiting NCT02562690
41 EKG Criteria and Identification of Acute Coronary Occlusion Recruiting NCT03863327
42 Diagnostic Accuracy of Electrocardiogram for Acute Coronary Occlusion Recruiting NCT04022668
43 Proteomic and Lipidomic Profiling of Coronary Thrombus in Acute Myocardial Infarction Recruiting NCT03731884
44 Predictive Value of HAS-BLED and CHA2DS2-Vasc Scores for Clinical Outcome After PCI Not yet recruiting NCT04047199
45 The Cholesterol-lowering Efficacy of Probiotic Lactobacillus Plantarum ECGC 13110402 (LPLDL®) in Hypercholesterolemic Adults Not yet recruiting NCT03540108
46 Long Term Clinical Outcomes of Angioplasty With Paclitaxel-coated Balloon Only Strategy for Coronary de Novo Lesions: a Single Center Registry Study Not yet recruiting NCT04022200

Search NIH Clinical Center for Coronary Thrombosis

Inferred drug relations via UMLS 72 / NDF-RT 51 :


heparin
heparin calcium
heparin sodium
HEPARIN SODIUM (BEEF LUNG)
heparin sodium, bovine
heparin sodium, porcine
Tenecteplase
Urokinase

Cochrane evidence based reviews: coronary thrombosis

Sources

Genetic Tests for Coronary Thrombosis

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Sources

Anatomical Context for Coronary Thrombosis

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MalaCards organs/tissues related to Coronary Thrombosis:

41
Heart, Endothelial, Neutrophil, Testes, Smooth Muscle, Kidney, Myeloid
Sources

Publications for Coronary Thrombosis

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Articles related to Coronary Thrombosis:

(show top 50) (show all 2299)
# Title Authors PMID Year
1
[Annexin A5 inhibits homocysteine-induced tissue factor expression and activity in vascular smooth muscle cells]. 9 38
20137335 2009
2
Atherothrombosis: role of tissue factor; link between diabetes, obesity and inflammation. 9 38
17249334 2007
3
Rapid release of active tissue factor from human arterial smooth muscle cells under flow conditions. 9 38
16528008 2006
4
Detection of von Willebrand factor and tissue factor in platelets-fibrin rich coronary thrombi in acute myocardial infarction. 9 38
16377278 2006
5
[Regulatory effect of IL-10 on expression of tissue factor induced by IL-6 in peripheral blood mononuclear cells]. 9 38
15972146 2005
6
Angiographic demonstration of coronary dethrombosis with eptifibatide. 9 38
15156011 2004
7
Tumor necrosis factor alpha activates the human plasminogen activator inhibitor-1 gene through a distal nuclear factor kappaB site. 9 38
14963043 2004
8
How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration. 9 38
12808446 2003
9
Plasminogen activator inhibitor-1, which is released from blood product transfusions, might be associated with (sub)acute thrombosis after coronary dilatation and stenting: a case report. 9 38
12644882 2003
10
Glycoprotein IIIa Pl(A1/A2) polymorphism and sudden cardiac death. 9 38
11028489 2000
11
Plasminogen activator inhibitor-1 (PAI-1) 4G/5G polymorphism, coronary thrombosis, and myocardial infarction in middle-aged Finnish men who died suddenly. 9 38
10928474 2000
12
Polymorphisms in the 5' regulatory region of the tissue factor gene and the risk of myocardial infarction and venous thromboembolism: the ECTIM and PATHROS studies. Etude Cas-Témoins de l'Infarctus du Myocarde. Paris Thrombosis case-control Study. 9 38
10712418 2000
13
The PlA2 polymorphism of the platelet glycoprotein IIIA gene as a risk factor for acute renal allograft rejection. 9 38
10589700 1999
14
Glycoprotein IIIa Pl(A) polymorphism associates with progression of coronary artery disease and with myocardial infarction in an autopsy series of middle-aged men who died suddenly. 9 38
10521390 1999
15
Local inhibition of tissue factor reduces the thrombogenicity of disrupted human atherosclerotic plaques: effects of tissue factor pathway inhibitor on plaque thrombogenicity under flow conditions. 9 38
10199872 1999
16
Association between the ACE genotype and coronary artery disease. Insights from studies on restenosis, vasomotion and thrombosis. 9 38
9796837 1998
17
Coronary thrombosis associated with antithrombin-III deficiency. 9 38
9327319 1997
18
Plasminogen activator inhibitor-1 promoter 4G/5G genotype and plasma levels in relation to a history of myocardial infarction in patients characterized by coronary angiography. 9 38
9012634 1997
19
Identification of active tissue factor in human coronary atheroma. 9 38
8822973 1996
20
Enhanced platelet aggregability under high shear stress after treadmill exercise in patients with effort angina. 9 38
8725732 1996
21
Comparison of desulfatohirudin (REVASC) and heparin as adjuncts to thrombolytic therapy with reteplase in a canine model of coronary thrombosis. 9 38
8735626 1996
22
Attenuation of the synthesis of plasminogen activator inhibitor type 1 by niacin. A potential link between lipid lowering and fibrinolysis. 9 38
7641354 1995
23
Novel antithrombotic approaches to coronary artery disease. 9 38
7863968 1995
24
Coronary thrombolysis with Desmodus salivary plasminogen activator in dogs. Fast and persistent recanalization by intravenous bolus administration. 9 38
8026028 1994
25
Combination of inhibition of thrombin and blockade of thromboxane A2 synthetase and receptors enhances thrombolysis and delays reocclusion in canine coronary arteries. 9 38
1451271 1992
26
Reduced synthesis of tissue plasminogen activator by vascular endothelium during acute myocardial infarction. 9 38
1497553 1992
27
Role of heparin in coronary thrombolysis. 9 38
1555478 1992
28
Double bolus administration of the novel recombinant plasminogen activator BM 06.022 improves coronary blood flow after reperfusion in a canine model of coronary thrombosis. 9 38
1606285 1992
29
Thrombolytic effects of a novel modified tissue plasminogen activator, E6010, on coronary thrombosis in the pig. 9 38
1513078 1992
30
Correlation between intracoronary thrombus components and coronary blood flow after percutaneous coronary intervention for acute myocardial infarction at different onset time. 38
31423433 2019
31
Adaptation to extreme environments in an admixed human population from the Atacama Desert. 38
31384924 2019
32
Therapeutic Ultrasound Increases Myocardial Blood Flow in Ischemic Myocardium and Cardiac Endothelial Cells: Results of In Vivo and In Vitro Experiments. 38
31272838 2019
33
Role of Platelet Activation and Oxidative Stress in the Evolution of Myocardial Infarction. 38
31280622 2019
34
Intracoronary recombinant tissue plasminogen activator in an infant with hypoplastic left heart syndrome and complete left main coronary artery thrombosis. 38
30702202 2019
35
Targeting thrombogenicity and inflammation in chronic HIV infection. 38
31206016 2019
36
Expression profile of integrin family genes in patients with myocardial infarction and in healthy subjects: an oligonucleotide microarray and QRT-PCR assessment. Preliminary results. 38
30784245 2019
37
[Coronary involvement and nephrotic syndrome in systemic lupus: A case report]. 38
30981562 2019
38
Sudden unexpected death due to coronary thrombosis associated with isolated necrotizing vasculitis in the coronary arteries of a young adult. 38
30810977 2019
39
Isotretinoin-associated possible Kounis syndrome: A case report and a review of other cardiovascular side effects reported in the literature. 38
31219450 2019
40
Clinical Significance of Platelet Volume and Other Platelet Parameters in Acute Myocardial Infarction and Stable Coronary Artery Disease. 38
30942294 2019
41
Pulmonary thromboembolism and coronary thrombosis after chemotherapy with cisplatin: simultaneous diagnosis with non-ECG gated computed tomography. 38
31210696 2019
42
Incomplete Kawasaki disease with development of fatal coronary artery thrombosis in a 13-year-old male. 38
31306942 2019
43
Coronary Artery Thrombosis in a Neonate With Critical Aortic Stenosis. 38
31034441 2019
44
Automated detection of vulnerable plaque in intravascular ultrasound images. 38
30426362 2019
45
Extracellular traps derived from macrophages, mast cells, eosinophils and neutrophils are generated in a time-dependent manner during atherothrombosis. 38
30506885 2019
46
Erratum to arterial events in cancer patients-the case of acute coronary thrombosis. 38
31179122 2019
47
Biomechanical Stress Profiling of Coronary Atherosclerosis: Identifying a Multifactorial Metric to Evaluate Plaque Rupture Risk. 38
31005542 2019
48
Acute Myocardial Infarction as an Initial Presentation of Protein C and Protein S Deficiency Followed by Dilated Cardiomyopathy in a Young Male. 38
31259110 2019
49
Low-dose i.v. urokinase for coronary thrombosis in Kawasaki disease. 38
30854729 2019
50
Update on pathological platelet activation in coronary thrombosis. 38
30317596 2019
Sources

Variations for Coronary Thrombosis

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Expression for Coronary Thrombosis

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Search GEO for disease gene expression data for Coronary Thrombosis.
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Pathways for Coronary Thrombosis

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Pathways related to Coronary Thrombosis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Response to elevated platelet cytosolic Ca2+ 66
Show member pathways
 12.69 VWF SERPINE1 SERPINC1 PLAT P2RY12 ITGB3
2
ECM-receptor interaction 37
Show member pathways
 11.9 VWF ITGB3 GP6 GP1BA
3
Complement and coagulation cascades 37 1
11.8 VWF SERPINE1 SERPINC1 PLAT F3
4
Adhesion 4
11.78 SERPINE1 ITGB3 F3
5
Platelet activation 37
11.65 VWF P2RY12 ITGB3 GP6 GP1BA
6
Integrin alphaIIb beta3 signaling 66
Show member pathways
 11.62 VWF ITGB3 GP1BA
7
Angiogenesis (CST) 4
11.56 VWF ITGB3 F3
8
Formation of Fibrin Clot (Clotting Cascade) 66
Show member pathways
 11.37 VWF SERPINE1 SERPINC1 PLAT GP6 GP1BA
9
Platelet Aggregation Inhibitor Pathway, Pharmacodynamics 61
11.33 VWF P2RY12 ITGB3 GP6
10
amb2 Integrin signaling 1
11.21 PLAT GP1BA
11
Platelet Adhesion to exposed collagen 66
10.66 VWF GP6 GP1BA
12
Dissolution of Fibrin Clot 66
10.61 SERPINE1 PLAT
13
GP1b-IX-V activation signalling 66
10.48 VWF GP1BA
Sources

GO Terms for Coronary Thrombosis

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Cellular components related to Coronary Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 VWF SERPINF1 SERPINE1 SERPINC1 PLAT F3
2 extracellular exosome GO:0070062 9.76 VWF SERPINF1 SERPINE1 SERPINC1 PLAT ITGB3
3 extracellular space GO:0005615 9.73 SERPINF1 SERPINE1 SERPINC1 PLAT GP1BA F3
4 cell surface GO:0009986 9.43 PLAT P2RY12 ITGB3 GP6 GP1BA F3
5 collagen-containing extracellular matrix GO:0062023 9.1 VWF SERPINF1 SERPINE1 SERPINC1 PLAT F3

Biological processes related to Coronary Thrombosis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 extracellular matrix organization GO:0030198 9.69 VWF SERPINE1 ITGB3
2 negative regulation of endopeptidase activity GO:0010951 9.65 SERPINF1 SERPINE1 SERPINC1
3 platelet degranulation GO:0002576 9.61 VWF SERPINE1 ITGB3
4 platelet activation GO:0030168 9.55 VWF P2RY12 ITGB3 GP6 GP1BA
5 platelet aggregation GO:0070527 9.5 P2RY12 ITGB3 GP1BA
6 cell-substrate adhesion GO:0031589 9.49 VWF ITGB3
7 blood coagulation, intrinsic pathway GO:0007597 9.46 VWF GP1BA
8 fibrinolysis GO:0042730 9.43 SERPINE1 PLAT GP1BA
9 hemostasis GO:0007599 9.43 VWF SERPINC1 P2RY12 GP6 GP1BA F3
10 regulation of blood coagulation GO:0030193 9.4 SERPINC1 GP1BA
11 smooth muscle cell migration GO:0014909 9.37 PLAT ITGB3
12 blood coagulation GO:0007596 9.23 VWF SERPINC1 PLAT P2RY12 ITGB3 GP6

Molecular functions related to Coronary Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serine-type endopeptidase inhibitor activity GO:0004867 9.13 SERPINF1 SERPINE1 SERPINC1
2 protease binding GO:0002020 9.02 VWF SERPINE1 SERPINC1 ITGB3 F3
Sources

Sources for Coronary Thrombosis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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