MCID: CWM001
MIFTS: 42

Cow Milk Allergy

Categories: Immune diseases

Aliases & Classifications for Cow Milk Allergy

MalaCards integrated aliases for Cow Milk Allergy:

Name: Cow Milk Allergy 12 15
Cow's Milk Protein Sensitivity 74
Bos Taurus Milk Allergy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060521
UMLS 74 C0266815

Summaries for Cow Milk Allergy

Disease Ontology : 12 A milk allergy triggered by Bos taurus milk.

MalaCards based summary : Cow Milk Allergy, also known as cow's milk protein sensitivity, is related to milk allergy and dermatitis, atopic. An important gene associated with Cow Milk Allergy is IL10 (Interleukin 10), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Caseins and Chelating Agents have been mentioned in the context of this disorder. Affiliated tissues include testes, bone and lung, and related phenotypes are hematopoietic system and immune system

Related Diseases for Cow Milk Allergy

Diseases related to Cow Milk Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 111, show less)
# Related Disease Score Top Affiliating Genes
1 milk allergy 31.1 CD79A IL10 IL5 RNASE3
2 dermatitis, atopic 30.2 IL10 IL5 RNASE3
3 ige responsiveness, atopic 30.0 IL10 IL5 RNASE3
4 hypereosinophilic syndrome 29.6 IL2RA IL5 RNASE3
5 sporotrichosis 10.3 CD79A IL10
6 clonorchiasis 10.2 CD79A IL10
7 anisakiasis 10.2 CD79A RNASE3
8 cephalosporin allergy 10.2 IL10 IL5
9 orofacial granulomatosis 10.2 CD79A IL10
10 nickel allergic contact dermatitis 10.2 IL10 IL5
11 allergic contact dermatitis 10.2 IL10 IL5
12 contact dermatitis 10.2 IL10 IL5
13 necatoriasis 10.2 IL10 IL5
14 apple allergy 10.2 IL10 IL5
15 lipoid nephrosis 10.2 CD79A IL10
16 gaucher disease, type ii 10.2 IL10 IL5
17 loeffler endocarditis 10.2 IL5 RNASE3
18 eosinophilic meningitis 10.2 IL10 IL5
19 multicentric castleman disease 10.2 IL10 IL5
20 filarial elephantiasis 10.2 IL10 IL5
21 paragonimiasis 10.2 IL5 RNASE3
22 cough variant asthma 10.2 IL5 RNASE3
23 inflammatory bowel disease 4 10.2 IL5 RNASE3
24 atopic keratoconjunctivitis 10.2 IL5 RNASE3
25 keratoconjunctivitis 10.2 IL5 RNASE3
26 henoch-schoenlein purpura 10.2 CD79A RNASE3
27 conjunctivitis 10.2 IL5 RNASE3
28 intrinsic asthma 10.2 IL5 RNASE3
29 keratoconjunctivitis sicca 10.2 CD79A IL10
30 eosinophilic gastroenteritis 10.2 IL5 RNASE3
31 latex allergy 10.2 IL5 RNASE3
32 ocular cicatricial pemphigoid 10.2 CD79A RNASE3
33 dermatitis 10.2
34 chronic conjunctivitis 10.2 IL5 RNASE3
35 status asthmaticus 10.2 IL5 RNASE3
36 chronic eosinophilic pneumonia 10.2 IL5 RNASE3
37 eosinophilic pneumonia 10.2 IL5 RNASE3
38 kimura disease 10.2 IL5 RNASE3
39 vernal keratoconjunctivitis 10.2 IL5 RNASE3
40 urinary schistosomiasis 10.2 IL5 RNASE3
41 paranasal sinus disease 10.2 IL10 IL5
42 sinusitis 10.2 IL5 RNASE3
43 strongyloidiasis 10.2 CD79A IL5
44 pollen allergy 10.2 IL5 RNASE3
45 conjunctival disease 10.2 IL5 RNASE3
46 pulmonary eosinophilia 10.1 IL5 RNASE3
47 spondyloarthropathy 10.1 IL10 TNFSF11
48 cellulitis 10.1 IL5 RNASE3
49 paracoccidioidomycosis 10.1 IL10 IL5
50 echinococcosis 10.1 IL10 IL5
51 onchocerciasis 10.1 IL5 RNASE3
52 pustulosis palmaris et plantaris 10.1 CD79A IL5
53 allergic conjunctivitis 10.1 IL5 RNASE3
54 filariasis 10.1 IL10 IL5
55 common cold 10.1 IL5 RNASE3
56 aggressive periodontitis 10.1 IL10 TNFSF11
57 cutaneous leishmaniasis 10.1 IL10 IL5
58 osteomyelitis 10.1 IL10 TNFSF11
59 chlamydia 10.1 CD79A IL10
60 aspergillosis 10.0 IL10 IL5
61 hyperlucent lung 10.0 IL10 IL2RA
62 bone inflammation disease 10.0 IL10 TNFSF11
63 otitis media 10.0 CD79A IL10 RNASE3
64 leukocyte disease 10.0 CD79A IL5
65 gastroesophageal reflux 10.0
66 thrombocytopenia 10.0
67 colitis 10.0
68 rickets 10.0
69 constipation 10.0
70 intermediate uveitis 10.0 IL10 IL2RA
71 toxoplasmosis 10.0 CD79A IL10
72 churg-strauss syndrome 10.0 IL10 IL5 RNASE3
73 nasal cavity disease 10.0 IL10 IL5 RNASE3
74 nose disease 10.0 IL10 IL5 RNASE3
75 respiratory allergy 10.0 IL10 IL5 RNASE3
76 parasitic helminthiasis infectious disease 10.0 IL10 IL5 RNASE3
77 food allergy 10.0 IL10 IL5 RNASE3
78 upper respiratory tract disease 10.0 IL10 IL5 RNASE3
79 gastroenteritis 10.0 IL10 IL5 RNASE3
80 bronchial disease 10.0 IL10 IL5 RNASE3
81 schistosomiasis 10.0 IL10 IL5 RNASE3
82 bronchiolitis 10.0 IL10 IL5 RNASE3
83 proteasome-associated autoinflammatory syndrome 1 10.0 IL10 IL5 RNASE3
84 allergic asthma 10.0 IL10 IL5 RNASE3
85 respiratory system disease 10.0 IL10 IL5 RNASE3
86 allergic hypersensitivity disease 10.0 IL10 IL5 RNASE3
87 allergic rhinitis 10.0 IL10 IL5 RNASE3
88 acute graft versus host disease 10.0 IL10 IL2RA
89 vernal conjunctivitis 10.0 IL2RA RNASE3
90 idiopathic neutropenia 10.0 IL10 IL2RA
91 lung disease 10.0 IL10 IL5 RNASE3
92 brucellosis 9.9 IL10 IL2RA
93 tropical spastic paraparesis 9.9 IL10 IL2RA
94 bullous pemphigoid 9.9 CD79A IL5 RNASE3
95 vogt-koyanagi-harada disease 9.9 IL10 IL2RA
96 extrinsic allergic alveolitis 9.9 IL10 IL2RA
97 toxic oil syndrome 9.9 IL2RA IL5
98 folliculitis 9.9 IL2RA IL5
99 bronchitis 9.9 IL5 RNASE3
100 chronic mucocutaneous candidiasis 9.9 IL10 IL2RA
101 chronic graft versus host disease 9.8 CD79A IL10 IL2RA
102 immune deficiency disease 9.8 CD79A IL10 IL2RA
103 radiculopathy 9.8 IL10 IL2RA IL5
104 wells syndrome 9.7 IL2RA IL5 RNASE3
105 sezary's disease 9.7 IL2RA IL5
106 skin disease 9.7 CD79A IL10 IL5 RNASE3
107 acquired immunodeficiency syndrome 9.7 IL10 IL2RA
108 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 9.6 IL10 IL2RA
109 asthma 9.5 IL10 IL2RA IL5 RNASE3
110 tetanus 9.5 CD79A IL10 IL2RA IL5
111 common variable immunodeficiency 9.5 CD79A IL10 IL2RA IL5

Graphical network of the top 20 diseases related to Cow Milk Allergy:



Diseases related to Cow Milk Allergy

Symptoms & Phenotypes for Cow Milk Allergy

MGI Mouse Phenotypes related to Cow Milk Allergy:

47 (showing 4, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.73 CD79A IL10 IL2RA IL5 LGALS3 TNFSF11
2 immune system MP:0005387 9.63 CD79A IL10 IL2RA IL5 LGALS3 TNFSF11
3 neoplasm MP:0002006 9.35 CD79A IL10 IL5 LGALS3 TNFSF11
4 respiratory system MP:0005388 9.02 IL10 IL2RA IL5 LGALS3 TNFSF11

Drugs & Therapeutics for Cow Milk Allergy

Drugs for Cow Milk Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 40, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Caseins Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
2 Chelating Agents Phase 4,Phase 2,Phase 1,Not Applicable,Early Phase 1
3 Soy Bean Phase 4,Not Applicable
4 Immunologic Factors Phase 2, Phase 3,Phase 1,Not Applicable,Early Phase 1
5
Omalizumab Approved, Investigational Phase 2,Early Phase 1 242138-07-4
6 Acidophilus Phase 2,Not Applicable
7 Vaccines Phase 2,Not Applicable
8 Antibodies Phase 2,Phase 1,Not Applicable
9 Anti-Asthmatic Agents Phase 2,Early Phase 1
10 Anti-Allergic Agents Phase 2,Early Phase 1
11 Respiratory System Agents Phase 2,Early Phase 1
12 Antibodies, Monoclonal Phase 2
13 Immunoglobulins Phase 2,Phase 1,Not Applicable
14 Immunoglobulin E Phase 1, Phase 2,Phase 2,Not Applicable
15 Whey Protein Phase 2,Not Applicable
16 Cassava Phase 1
17
Calcium Carbonate Approved, Investigational Not Applicable 471-34-1
18 Menaquinone Approved, Investigational Not Applicable 1182-68-9
19
Phylloquinone Approved, Investigational Not Applicable 84-80-0
20
Benzocaine Approved, Investigational Not Applicable 1994-09-7, 94-09-7 2337
21
tannic acid Approved Not Applicable 1401-55-4
22
Calcium Approved, Nutraceutical Not Applicable 7440-70-2 271
23
Menadione Approved, Nutraceutical Not Applicable 58-27-5 4055
24 Calcium, Dietary Not Applicable
25 Hormones Not Applicable
26 Complement System Proteins Not Applicable
27 Dermatologic Agents
28 Nutrients Not Applicable
29 Vitamin K 2 Not Applicable
30 Vitamin MK 7 Not Applicable
31 Flax Not Applicable
32 Hemostatics Not Applicable
33 Antifibrinolytic Agents Not Applicable
34 Coagulants Not Applicable
35 Micronutrients Not Applicable
36 naphthoquinone Not Applicable
37 Trace Elements Not Applicable
38 Vitamins Not Applicable
39 Vitamin K Not Applicable
40 Immunoglobulin G

Interventional clinical trials:

(showing 99, show less)
# Name Status NCT ID Phase Drugs
1 Growth, Safety and Tolerance of a Rice Protein Hydrolysate Formula in Infants With Cow's Milk Protein Allergy Unknown status NCT02405923 Phase 4
2 Safety of Oral Immunotherapy for Cow's Milk Allergy in School-aged Children Completed NCT01361347 Phase 4
3 Basophil Activation Test (BAT) Sensitivity in Child Food Allergy Recruiting NCT01966640 Phase 4
4 Parmigiano-Reggiano Cheese as a Possible Strategy to Acquire Oral Tolerance in Children With Cow's Milk Allergy Unknown status NCT02081651 Phase 3
5 Cow Milk Allergy: Evaluation of the Efficacy of a New Thickened Extensively Hydrolyzed Formula in Infants With Confirmed Cow Milk Allergy Completed NCT02351531 Phase 3
6 Evaluation of the Hypoallergenicity of an Extensively Hydrolyzed Formula Completed NCT02711163 Phase 3
7 Improving the Safety of Oral Immunotherapy for Cow's Milk Allergy Recruiting NCT02216175 Phase 2, Phase 3
8 Epigenetic Effects Elicited By Lactobacillus GG In Children With Cow's Milk Allergy Unknown status NCT02062476 Phase 2
9 Evaluation of the Efficacy of a New Infant Formula in Subjects With Cow's Milk Allergy Unknown status NCT02149134 Phase 2
10 Study to Assess Hypoallergenicity of a New Amino-acid Based Infant Formula in Children With Cow's Milk Allergy Unknown status NCT02414243 Phase 2
11 Efficacy and Safety of Viaskin Milk in Children With IgE-Mediated Cow's Milk Allergy Unknown status NCT02223182 Phase 1, Phase 2
12 The Effect of Baked Milk on Cow's Milk Allergy Completed NCT02738060 Phase 2
13 OIT and Xolair® (Omalizumab) in Cow's Milk Allergy Completed NCT01157117 Phase 2 Milk powder
14 Milk ALLERGY ELIMINATION THROUGH NAET® (Nambudripad's Allergy Elimination Techniques). Completed NCT00328731 Phase 1, Phase 2
15 Free Amino Acid-based Formula to Treat Children Cow's Milk Protein Allergy Completed NCT02536482 Phase 2
16 A Randomized, Double-Blind, Placebo-Controlled Study of Oral Milk Immunotherapy for Cow's Milk Allergy Completed NCT00465569 Phase 1, Phase 2 cow's milk powder
17 Study of Milk Allergy and Tolerance in Children Completed NCT00778258 Phase 2
18 The Safety and Efficacy of Sublingual/Oral Immunotherapy for the Treatment of Milk Protein Allergy Completed NCT00732654 Phase 1, Phase 2 Milk Protein Extract Immunotherapy goal of 4mg/day;Milk Protein Extract Immunotherapy goal of 7mg/day;Milk Powder Immunotherapy goal dose 2000 mg/day;Milk Powder Immunotherapy goal dose 1000mg/day
19 Milk Patch for Eosinophilic Esophagitis Completed NCT02579876 Phase 2 Viaskin Milk 500 mcg;Viaskin Placebo
20 A Clinical Study to Investigate the Effects of an Infant Formula Containing Partially Hydrolysed Proteins on Growth, Safety and Tolerance in Healthy Term Infants Completed NCT03062761 Phase 2
21 Tolerance of Infants With Cow's Milk Protein Allergy to Extensively Hydrolyzed Rice Protein or Casein Infant Formulas Completed NCT01909661 Phase 2
22 Food-Specific and Component IgE Threshold Levels That Predict Food Allergy in People With Elevated Total Serum IgE Levels and Atopic Dermatitis Recruiting NCT03835767 Phase 2
23 Impact of Infant Formula on Resolution of Cow's Milk Allergy Terminated NCT02719405 Phase 2
24 Baked Milk Oral Immunotherapy for Cow's Milk Allergy Enrolling by invitation NCT03462030 Phase 1 Baked non-fat cow's milk powder;Placebo: Tapioca Powder
25 Hypoallergenicity To Substitutive Formulas In Children With Cow's Milk Allergy Unknown status NCT02144428
26 Oral Tolerance in Cow’s Milk Allergy in the Infant Unknown status NCT00298376
27 Cow's Milk Allergy in Infants With Obstructive Sleep Apnea (OSA) Unknown status NCT00659854 Not Applicable
28 Nutrition in Children With Food Allergy Unknown status NCT01583907
29 Effect Of Lactobacillus GG on Atopic March Unknown status NCT01891916 Not Applicable
30 Young Adults With Life Threatening Cow's Milk Allergy: Risks of Decrease Bone Mineralization and Methods of Calcium Supplementation Unknown status NCT01930266 Not Applicable
31 Use of Baked Milk in Oral Immunotherapy for Severe IgE-mediated Cow's Milk Protein Allergic Patients Unknown status NCT01968278 Not Applicable
32 Cow's Milk and Hen's Egg Hyposensitization in Adults Unknown status NCT02083471 Not Applicable
33 The Influence of Probiotics on the Immunologic Response to Vaccinations in Infants Unknown status NCT00645996 Not Applicable
34 Epigenetic Effects Involved in Children With Cow's Milk Allergy (EPICMA) Completed NCT02466035 Not Applicable
35 Effect of Therapy With Aminoacid Based Formula Versus Hydrolyzed Whey Proteins in Children With Cow's Milk Allergy Completed NCT02379598
36 Tolerance to a New Free Amino Acid-based Formula in Children With IgE or Non-IgE-mediated Cow's Milk Allergy Completed NCT01622426 Not Applicable
37 A Growth and Hypoallergenicity Study of a New Formula for Infants With Cow Milk Allergy Completed NCT00664768 Not Applicable
38 Cow's Milk Allergy and Functional Gastrointestinal Disorders Completed NCT01901380
39 Oral Immunotherapy in Cow's Milk Allergy (CMA) in Children : "Petit Lait" Study Completed NCT02465905 Not Applicable
40 Prevention of Cow's Milk Allergy in Children Completed NCT00792090 Not Applicable
41 Epigenetic Features of FoxP3 in Children With Cow's Milk Allergy Completed NCT02779881
42 Effects of Different Dietary Regimens on Tolerance Acquisition in Children With Cow's Milk Allergy Completed NCT01634490
43 Camel's Milk as a Safe Alternative in Cow's Milk Allergy Completed NCT01223885 Not Applicable
44 Specific Oral Tolerance Induction to Cow's Milk Allergy Completed NCT01199484 Not Applicable
45 Formula for Children With Cow's Milk Allergy Completed NCT02317952 Not Applicable
46 Polymerized Beta-lactoglobulin Comparative Immunoreactivity Completed NCT01589731
47 Isomil Post Marketing Observational Study Completed NCT01809951
48 Tolerability and Safety of An Infant Formula Completed NCT00938483 Not Applicable
49 Hypoallergenicity Evaluation of a New Extensively Hydrolyzed Formula Completed NCT03236207 Not Applicable
50 Evaluation of Hypoallergenicity of a New Extensively Hydrolyzed Formula Completed NCT02450643 Not Applicable
51 Sublingual Milk Immunotherapy in Children Completed NCT00874627 Not Applicable
52 Oral Immunotherapy With Baked Milk Products for Patients Allergic to Cow's Milk - A Multicenter Study Completed NCT01760837 Not Applicable
53 Partially Hydrolyzed Whey Formula in Cow's Milk Allergic Patients Completed NCT02397876 Not Applicable
54 Xolair Treatment for Milk Allergic Children Completed NCT00968110 Early Phase 1 omalizumab
55 Symptoms Based Awareness Confirmation Study - CoMiSS Validation Completed NCT03004729 Not Applicable
56 A Double-blind Randomized Controlled Trial of a Thickened Amino-acid-based Formula in Children Allergic to Cow's Milk and to Protein Hydrolysates Completed NCT01940068 Not Applicable
57 Elemental Formula Hypoallergenicity Completed NCT01569776 Not Applicable
58 An Interventional Study of Milk Allergy Completed NCT00578656 Early Phase 1
59 Double Blind Controlled Trial of an Extensively Hydrolyzed Formula With a Probiotic vs. an Extensively Hydrolyzed Formula Without a Probiotic Completed NCT01181297 Not Applicable
60 Double-Blind, Parallel, Randomised Study to Investigate the Effect of Oral Probiotics in Infants With Atopic Dermatitis Completed NCT00224432 Not Applicable probiotics: Lactobacillus GG, lactobacillus Rhamnosus
61 An Observational Study of Childhood Food Allergy Completed NCT00356174
62 Milk Oral Immunotherapy in Children to Treat Food Allergy Completed NCT01162473 Early Phase 1 Milk Protein Powder
63 Specific Oral Tolerance Induction in Children Allergic to Cow's Milk Proteins Completed NCT01641731 Not Applicable
64 Extensively Hydrolyzed Formula: Hypoallergenicity Completed NCT01278446 Not Applicable
65 Amino Acid Feed Children's Study Completed NCT02569840 Not Applicable
66 Efficacy of a New Thickened Extensively Hydrolyzed Formula Completed NCT01985607 Not Applicable
67 Arabic Gum-Absorption Study Completed NCT00858767 Not Applicable
68 Milk-induced Gastrointestinal Symptoms in Infants Completed NCT01684319 Not Applicable
69 Study to Identify Non-Invasive Markers of Gastrointestinal Allergy Completed NCT00272818
70 Post-exercise Recovery After Dietary Protein Ingestion in Healthy Young Men (Meat-Milk Study) Completed NCT01578590 Not Applicable
71 Impact of Vaccination on Th2 Immunity in Infancy Completed NCT02213341
72 Potential Allergens in Wine: Double-blind Placebo-controlled Trial Completed NCT00163735 Not Applicable Administration of wine fined with potential food allergens
73 Growth of Infants With Cow's Milk Allergy Fed an Amino Acid-based Formula Containing Two Human Milk Oligosaccharides Recruiting NCT03661736
74 Dietary Choice for the Management of Cow's Milk Allergy Influences Other Allergic Manifestations Recruiting NCT03861910
75 Microbiota as Potential Target for Food Allergy Recruiting NCT02087930
76 Swedish Study of Immunotherapy for Milk Allergy in Children Recruiting NCT03819556 Not Applicable
77 Synbiotic Extensively Hydrolysed Feed Study Recruiting NCT03874104 Not Applicable
78 Evaluation of the Hypoallergenicity of a New Formula Based on Hydrolyzed Rice Proteins Recruiting NCT03557671 Not Applicable
79 Tolerability of Hypoallergenic Formula in Children With Cow's Milk Allergy Recruiting NCT03909113 Not Applicable
80 Milk Desensitization in Children Recruiting NCT03644381 Not Applicable
81 Growth and Plasma Amino Acids in Infants With CMPA and Treated With a Newly Innovated Amino Acid Formula Recruiting NCT01637688
82 Assessment of Cow's Milk-related Symptom Scoring Awareness Tool in Young Turkish Children Recruiting NCT03223181
83 The Effect of Per Oral Immunotherapy in Severe Milk, Peanut and Egg Allergy in Adults Recruiting NCT03361072 Not Applicable
84 Efficacy of the "Milk Ladder" Intervention in the Development of Tolerance and the Recognition of B Cell Epitopes in Babies Who Are Allergic to Cow's Milk Proteins Recruiting NCT03466931 Not Applicable
85 Association Between Soy Based Formula in Infancy and Puberty Recruiting NCT02908971
86 Basophil Activation Test to Diagnose Food Allergy Recruiting NCT03309488
87 The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults Active, not recruiting NCT01822353 Not Applicable
88 The Utility of Food-Specific IgE Measured With the IMMULITE 2000 Assay to Predict Symptomatic Food Allergy Active, not recruiting NCT01950533
89 Oral Immunotherapy in Food Allergy in Finland Active, not recruiting NCT02640014 Not Applicable
90 The Influence of Early and Continuous Exposure of Infants to Cow's Milk Formula on the Prevention of Milk Allergy Not yet recruiting NCT02785679 Not Applicable
91 Step Down Approach in Children With Cow Milk Allergy Not yet recruiting NCT03449537 Not Applicable
92 COMISS Score for Detection of Cow's Milk Protein Allergy in Children With Recrrent or Persistent Gastrointestinal Manifistations in Infants Attending Assuit University Children Hospital - Egypt Not yet recruiting NCT03664076
93 Diagnosis of Cow's Milk Protein Allergy Among Infants and Children in Assuit University Children Hospital Not yet recruiting NCT03456479 Not Applicable
94 Determine Immunoglobulin G4 (IgG4) Standards for Cow's Milk and Egg in Different Populations of Allergic and Non-allergic Children Not yet recruiting NCT03776474
95 Evaluation of the Efficacy of an Amino Acid Based Formula in Infants Terminated NCT01584245 Not Applicable
96 An Elimination Diet Using a New Amino Acid Based Formula: Immunological and Clinical Effects in Cow's Milk Allergy Terminated NCT01109966 Not Applicable
97 the Effectiveness of Probiotics on Atopic Dermatitis With Cow Milk Allergy Withdrawn NCT01045486 Not Applicable ATP mixed probiotics;Placebo
98 Evaluation of Fatty Acid Levels and Growth in Infants Fed Amino Acid Based (AA) Formulas Withdrawn NCT01470768 Not Applicable
99 Safety Study of Infant Formula With Partially Hydrolized Whey Withdrawn NCT00548106 Not Applicable

Search NIH Clinical Center for Cow Milk Allergy

Genetic Tests for Cow Milk Allergy

Anatomical Context for Cow Milk Allergy

MalaCards organs/tissues related to Cow Milk Allergy:

42
Testes, Bone, Lung, B Cells, Breast, T Cells, Skin

Publications for Cow Milk Allergy

Articles related to Cow Milk Allergy:

(showing 71, show less)
# Title Authors Year
1
A new score to predict allergic march in patients with IgE-mediated cow milk allergy. ( 31018894 )
2019
2
Brazilian artisanal ripened cheeses as sources of proteolytic lactic acid bacteria capable of reducing cow milk allergy. ( 29654625 )
2018
3
Association between Caesarean Delivery and Isolated Doses of Formula Feeding in Cow Milk Allergy. ( 28787733 )
2017
4
Matrix effect on baked milk tolerance in children with IgE cow milk allergy. ( 27480790 )
2016
5
IgE-mediated cow milk allergy and infantile colic: diagnostic and management challenges. ( 23391944 )
2013
6
A comparison between two different in vitro basophil activation tests for gluten- and cow's milk protein sensitivity in irritable bowel syndrome (IBS)-like patients. ( 23183757 )
2013
7
Non-IgE-mediated cow milk allergy is linked to early childhood clusters of commonly seen illnesses: a pilot study. ( 22013147 )
2012
8
Cost-effectiveness of using an extensively hydrolysed formula compared to an amino acid formula as first-line treatment for cow milk allergy in the UK. ( 22360663 )
2012
9
Allergen-specific responses of CD19(+)CD5(+)Foxp3(+) regulatory B cells (Bregs) and CD4(+)Foxp3(+) regulatory T cell (Tregs) in immune tolerance of cow milk allergy of late eczematous reactions. ( 22398308 )
2012
10
Characteristics of patients suffering from cow milk allergy. ( 22722049 )
2012
11
Response to: Cost-effectiveness of using an extensively hydrolysed formula compared to an amino acid formula as first-line treatment for cow milk allergy in the UK. ( 22985421 )
2012
12
Impact of oral immunotherapy on quality of life in children with cow milk allergy: a pilot study. ( 23058033 )
2012
13
Camel milk is a safer choice than goat milk for feeding children with cow milk allergy. ( 23724227 )
2011
14
Resource implications and budget impact of managing cow milk allergy in the UK. ( 20092426 )
2010
15
Oligosaccharide-induced whey-specific CD25(+) regulatory T-cells are involved in the suppression of cow milk allergy in mice. ( 20164372 )
2010
16
Budget impact of managing cow milk allergy in the Netherlands. ( 20469979 )
2010
17
Modelling the health economic impact of managing cow milk allergy in South Africa. ( 20469980 )
2010
18
Characterisation of allergen-specific responses of IL-10-producing regulatory B cells (Br1) in Cow Milk Allergy. ( 20646682 )
2010
19
Diagnosis of cow milk allergy in the gut, never an easy task. ( 20711552 )
2010
20
Basophil activation test based on the expression of CD203c in the diagnostics of cow milk allergy in children. ( 21147615 )
2010
21
A survey on clinical presentation and nutritional status of infants with suspected cow' milk allergy. ( 20416046 )
2010
22
Modelling the resource implications and budget impact of managing cow milk allergy in Australia. ( 19192978 )
2009
23
Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3. ( 19309568 )
2009
24
Tolerance to water buffalo milk in a child with cow milk allergy. ( 19441608 )
2009
25
Cow milk allergy symptoms are reduced in mice fed dietary synbiotics during oral sensitization with whey. ( 19474160 )
2009
26
Effects of heating and glycation of beta-lactoglobulin on its recognition by IgE of sera from cow milk allergy patients. ( 19489627 )
2009
27
Modelling the resource implications and budget impact of new reimbursement guidelines for the management of cow milk allergy in Finland. ( 18341760 )
2008
28
Specific oral tolerance induction in children with very severe cow-milk allergy. ( 20477567 )
2008
29
Cow's milk protein sensitivity assessed by the mucosal patch technique is related to irritable bowel syndrome in patients with primary Sjögren's syndrome. ( 18498540 )
2008
30
Hypogammaglobulinaemia secondary to cow-milk allergy in children under 2 years of age. ( 17498216 )
2007
31
Lessons from the clinical course of IgE-mediated cow milk allergy in Israel. ( 17561928 )
2007
32
Comparisons of a chicken-based formula with soy-based formula in infants with cow milk allergy. ( 18042533 )
2007
33
A follow-up study of nutrient intake, nutritional status, and growth in infants with cow milk allergy fed either a soy formula or an extensively hydrolysed whey formula. ( 16707991 )
2006
34
A follow-up study of nutrient intake, nutritional status, and growth in infants with cow milk allergy fed either a soy formula or an extensively hydrolyzed whey formula. ( 16002812 )
2005
35
Cesarean delivery and cow milk allergy/intolerance. ( 16076303 )
2005
36
The almond milk: a new approach to the management of cow-milk allergy/intolerance in infants. ( 16172596 )
2005
37
The role of cow milk allergy in increasing the severity of atopic dermatitis. ( 15015834 )
2004
38
Bone mineral status in children with cow milk allergy. ( 15610372 )
2004
39
Cow milk allergy presenting as colitis. ( 12802687 )
2003
40
Hematemesis in infants induced by cow milk allergy. ( 15198338 )
2003
41
Gastroesophageal reflux and cow milk allergy: is there a link? ( 12415039 )
2002
42
Oral desensitisation in cow milk allergy: immunological findings. ( 12593788 )
2002
43
Relation between weak HLA-DR expression on human breast milk macrophages and cow milk allergy (CMA) in suckling infants. ( 9890612 )
1999
44
Markedly high eosinophilia and an elevated serum IL-5 level in an infant with cow milk allergy. ( 10094215 )
1999
45
Soy protein for the prevention and treatment of children with cow-milk allergy. ( 9848515 )
1998
46
Oral cow milk challenge abolishes antigen-specific interferon-gamma production in the peripheral blood of children with atopic dermatitis and cow milk allergy. ( 9088654 )
1997
47
Cow-milk allergy. ( 21781812 )
1997
48
Cow milk allergy in infancy and early childhood. ( 8729658 )
1996
49
Efficacy and safety of hydrolyzed cow milk and amino acid-derived formulas in infants with cow milk allergy. ( 7562275 )
1995
50
Chronic constipation as a symptom of cow milk allergy. ( 7815220 )
1995
51
The cow milk allergy complex: overlapping disease profiles in infancy. ( 8647057 )
1995
52
Cow's milk protein sensitivity: a possible cause of nephrotic syndrome in early infancy. ( 7472914 )
1995
53
Cow milk allergy within the spectrum of atopic disorders. ( 7889427 )
1994
54
Safety of a new, ultrafiltrated whey hydrolysate formula in children with cow milk allergy: a clinical investigation. ( 8353646 )
1993
55
Gamma-interferon production in cow milk allergy. ( 8457036 )
1993
56
Local immune response in patients with cow milk allergy: follow-up of patients retaining allergy or becoming tolerant. ( 1370536 )
1992
57
Cow milk allergy in infancy and hypoallergenic formulas. ( 1447628 )
1992
58
Prospective estimation of IgG, IgG subclass and IgE antibodies to dietary proteins in infants with cow milk allergy. Levels of antibodies to whole milk protein, BLG and ovalbumin in relation to repeated milk challenge and clinical course of cow milk allergy. ( 1510234 )
1992
59
Immunologic changes associated with the development of tolerance in children with cow milk allergy. ( 1517910 )
1992
60
Levels of IgA and cow milk antibodies in breast milk vs. the development of atopy in children. Low colostral IgA associated with cow milk allergy. ( 1809019 )
1991
61
Management of infants with cow milk allergy. ( 1809021 )
1991
62
Natural history and immunological markers in children with cow milk allergy. ( 1809024 )
1991
63
Safety of casein hydrolysate formula in children with cow milk allergy. ( 2007924 )
1991
64
Infants and children with cow milk allergy/intolerance. Investigation of the uptake of cow milk protein and activation of the complement system. ( 2252165 )
1990
65
A prospective study of cow milk allergy in Danish infants during the first 3 years of life. Clinical course in relation to clinical and immunological type of hypersensitivity reaction. ( 2288394 )
1990
66
IgE antibodies to hydrolysates of cow milk proteins in children with cow milk allergy. ( 2310057 )
1990
67
Value of immunologic tests in cow milk allergy. ( 2327558 )
1990
68
Natural history of cow milk allergy: clinical outcome. ( 2348289 )
1990
69
Cow's milk protein sensitivity during infancy in patients with inflammatory bowel disease. ( 2371984 )
1990
70
Maternal immune status against beta-lactoglobulin and cow milk allergy in the infant. ( 2596761 )
1989
71
Leukocyte migration inhibition test in children with cow milk allergy. ( 3425860 )
1987

Variations for Cow Milk Allergy

Expression for Cow Milk Allergy

Search GEO for disease gene expression data for Cow Milk Allergy.

Pathways for Cow Milk Allergy

Pathways related to Cow Milk Allergy according to GeneCards Suite gene sharing:

(showing 20, show less)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.46 CD79A IL10 IL2RA IL5 LGALS3 RNASE3
2
Show member pathways
13 IL10 IL2RA IL5 TNFSF11
3
Show member pathways
12.93 IL10 IL2RA IL5 TNFSF11
4
Show member pathways
12.41 IL10 IL2RA IL5 RNASE3
5
Show member pathways
12.28 CD79A IL10 IL2RA
6
Show member pathways
12.24 IL10 IL2RA IL5
7
Show member pathways
12.04 IL10 IL2RA IL5
8
Show member pathways
11.9 IL10 IL2RA IL5
9
Show member pathways
11.73 IL10 IL2RA IL5
10 11.54 CD79A IL10 IL2RA LGALS3 TNFSF11
11 11.47 IL10 IL5
12
Show member pathways
11.46 IL2RA IL5
13 11.36 IL10 IL5
14 11.34 IL10 IL2RA IL5
15 11.32 CD79A IL10 IL2RA IL5
16 11 IL2RA IL5
17 10.99 IL10 IL2RA IL5
18 10.92 IL10 IL5
19 10.85 IL10 IL5
20 10.81 IL10 IL5 TNFSF11

GO Terms for Cow Milk Allergy

Cellular components related to Cow Milk Allergy according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.35 IL10 IL5 LGALS3 RNASE3 TNFSF11
2 extracellular space GO:0005615 9.02 IL10 IL5 LGALS3 RNASE3 TNFSF11

Biological processes related to Cow Milk Allergy according to GeneCards Suite gene sharing:

(showing 8, show less)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.61 IL10 IL5 TNFSF11
2 immune response GO:0006955 9.46 IL10 IL2RA IL5 TNFSF11
3 B cell differentiation GO:0030183 9.4 CD79A IL10
4 monocyte chemotaxis GO:0002548 9.37 LGALS3 TNFSF11
5 negative regulation of T cell proliferation GO:0042130 9.32 IL10 IL2RA
6 B cell proliferation GO:0042100 9.26 CD79A IL10
7 positive regulation of DNA-binding transcription factor activity GO:0051091 9.13 IL10 IL5 TNFSF11
8 cytokine-mediated signaling pathway GO:0019221 8.92 IL10 IL2RA IL5 TNFSF11

Molecular functions related to Cow Milk Allergy according to GeneCards Suite gene sharing:

(showing 1, show less)
# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.8 IL10 IL5 TNFSF11

Sources for Cow Milk Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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