YABA
MCID: CWP001
MIFTS: 46

Cowpox (YABA)

Categories: Infectious diseases, Skin diseases

Aliases & Classifications for Cowpox

MalaCards integrated aliases for Cowpox:

Name: Cowpox 12 74 54 43 15 17 71
Yaba 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8956
ICD9CM 34 051.01
MeSH 43 D015605
SNOMED-CT 67 70090004
ICD10 32 B08.010
UMLS 71 C0010232

Summaries for Cowpox

Disease Ontology : 12 A viral infectious disease that results in infection in rodents, cows, and humans, located in skin, has material basis in Cowpox virus, which is transmitted by contact with an infected animal. The infection results in formation of vesicopustular lesions on the hands or face.

MalaCards based summary : Cowpox, also known as yaba, is related to vaccinia and yellow fever. An important gene associated with Cowpox is CASP1 (Caspase 1), and among its related pathways/superpathways are Innate Immune System and Apoptotic Pathways in Synovial Fibroblasts. The drugs Vaccines and Rho(D) Immune Globulin have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and testes, and related phenotypes are Increased viability with MLN4924 (a NAE inhibitor) and Increased viability with MLN4924 (a NAE inhibitor)

Wikipedia : 74 Cowpox is an infectious disease caused by the cowpox virus. The virus, part of the genus Orthopoxvirus,... more...

Related Diseases for Cowpox

Diseases related to Cowpox via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 225)
# Related Disease Score Top Affiliating Genes
1 vaccinia 31.6 IL6 GZMB EIF2S1 CD80
2 yellow fever 30.7 IL6 CXCL1 CASP3
3 lymphadenitis 30.6 FAS CXCL8 CASP3
4 stomatitis 30.5 MX1 IL6 CXCL8
5 conjunctivitis 30.4 TNFRSF1A IL6 CXCL8
6 bronchopneumonia 30.4 IL6 CXCL8 CD8A
7 syphilis 30.3 IL6 FAS CD8A
8 tonsillitis 30.2 IL6 CXCL8 CXCL1 CASP3
9 cytomegalovirus infection 30.1 IL6 FAS CXCL8 CASP3
10 pneumonia 30.1 IL6 CXCL8 CXCL1 CD8A
11 exanthem 30.1 IL6 CXCL8 CD8A
12 herpes simplex 30.0 IL6 EIF2S1 CD8A CASP8
13 skin disease 29.7 MX1 IL6 CXCL8 CD8A CASP8 CASP1
14 panniculitis 29.6 GZMB FAS CD8A CASP3
15 viral infectious disease 29.5 MX1 KLRK1 IL6 GZMB FAS EIF2S1
16 autoimmune disease 29.4 TNFRSF1A KLRK1 IL6 FAS CXCL8 CD86
17 bacterial infectious disease 29.3 MX1 IL6 CXCL8 CD8A CD86 CD80
18 smallpox 10.9
19 variola major 10.9
20 monkeypox 10.7
21 idiopathic anterior uveitis 10.5 IL6 CXCL8
22 pneumococcal meningitis 10.5 CASP3 CASP1
23 streptococcal toxic-shock syndrome 10.5 IL6 CXCL8
24 acute transverse myelitis 10.5 IL6 CXCL8
25 tendinopathy 10.5 CASP8 CASP3
26 acute generalized exanthematous pustulosis 10.4 MX1 CXCL8
27 esophagus melanoma 10.4 FAS CXCL8
28 fuchs' heterochromic uveitis 10.4 IL6 CXCL8
29 fibroma 10.4
30 post-transplant lymphoproliferative disease 10.4 TNFRSF1A IL6 CASP8
31 bacteriuria 10.3 IL6 CXCL8 CXCL1
32 endometritis 10.3 IL6 CXCL8 CXCL1
33 brucellosis 10.3 IL6 CXCL8 CD86
34 avian influenza 10.3 IL6 CXCL8 CASP8
35 extrinsic allergic alveolitis 10.3 IL6 CXCL8 CD80
36 spinal cord injury 10.3 IL6 CXCL8 CASP3
37 acute cystitis 10.3 IL6 CXCL8 CXCL1
38 dystrophinopathies 10.3 TNFRSF1A CASP8
39 silicosis 10.3 FAS CXCL8 CASP1
40 dengue hemorrhagic fever 10.3 MX1 IL6 CXCL8
41 helicobacter pylori infection 10.3 CXCL8 CXCL1 CASP3
42 myelitis 10.3 TNFRSF1A IL6 CXCL8
43 prostatitis 10.3 IL6 CXCL8 CASP3
44 typhoid fever 10.3 TNFRSF1A IL6 CASP1
45 duodenal ulcer 10.3 IL6 CXCL8 CXCL1
46 anthrax disease 10.3
47 lymphocytic choriomeningitis 10.3 IL6 CXCL8 CD86 CD80
48 bacterial meningitis 10.3 IL6 CXCL8 CXCL1
49 pericarditis 10.3 TNFRSF1A IL6 CXCL8
50 chlamydia 10.3 IL6 CXCL8 CASP1

Graphical network of the top 20 diseases related to Cowpox:



Diseases related to Cowpox

Symptoms & Phenotypes for Cowpox

GenomeRNAi Phenotypes related to Cowpox according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased viability with MLN4924 (a NAE inhibitor) GR00250-A-1 9.91 CASP1 CASP4 CASP5 CASP8 MX1 XIAP
2 Increased viability with MLN4924 (a NAE inhibitor) GR00250-A-2 9.91 CASP1 CASP3 CASP4 CASP5 CASP8 FAS
3 Increased viability with MLN4924 (a NAE inhibitor) GR00250-A-3 9.91 CASP8 XIAP
4 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.58 CASP3 CXCL8 EIF2S1 FAS GZMB TNFRSF1A
5 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.58 CASP1 CASP3 CASP4 CASP5 CXCL8 EIF2S1
6 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-3 9.58 CASP8

MGI Mouse Phenotypes related to Cowpox:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.13 CASP1 CASP3 CASP4 CASP8 CD80 CD86
2 cellular MP:0005384 10.11 CASP1 CASP3 CASP4 CASP8 CD80 CD86
3 hematopoietic system MP:0005397 10.07 CASP1 CASP3 CASP4 CASP8 CD80 CD86
4 immune system MP:0005387 9.93 CASP1 CASP3 CASP4 CASP8 CD80 CD86
5 integument MP:0010771 9.61 CASP1 CASP3 CASP4 CASP8 CD8A FAS
6 renal/urinary system MP:0005367 9.28 CASP1 CASP3 CASP4 CASP8 CD8A FAS

Drugs & Therapeutics for Cowpox

Drugs for Cowpox (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 2
2 Rho(D) Immune Globulin Phase 2
3 gamma-Globulins Phase 2
4 Horseradish Tree
5 Antibodies Early Phase 1
6 Immunoglobulins, Intravenous Early Phase 1
7 Immunologic Factors Early Phase 1
8 Immunoglobulins Early Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation and Treatment of Ocular Complications of Vaccinia Vaccination: Suitability of NP-016 Vaccinia Immune Globulin (VIG) for Sight-Threatening Conditions [VIG31] Completed NCT00081835 Phase 2 NP-016 Vaccine Immune Globulin (IV-VIG)
2 Effect of Moringa Oleifera on Bone Density in Post-Menopausal Women Completed NCT03026660
3 Innovative Tools to Expand HIV Self-Testing Active, not recruiting NCT04070287 Early Phase 1

Search NIH Clinical Center for Cowpox

Cochrane evidence based reviews: cowpox

Genetic Tests for Cowpox

Anatomical Context for Cowpox

The Foundational Model of Anatomy Ontology organs/tissues related to Cowpox:

19
Skin

MalaCards organs/tissues related to Cowpox:

40
Skin, T Cells, Testes, Kidney, Ovary, Bone, Lung

Publications for Cowpox

Articles related to Cowpox:

(show top 50) (show all 1207)
# Title Authors PMID Year
1
Identification of proteins cleaved downstream of caspase activation in monocytes undergoing macrophage differentiation. 61 54
16636047 2006
2
Alkylphosphocholine-induced glioma cell death is BCL-X(L)-sensitive, caspase-independent and characterized by massive cytoplasmic vacuole formation. 61 54
15389288 2004
3
Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells. 54 61
15475455 2004
4
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes mitochondrial dysfunction and apoptosis induced by 7-hydroxystaurosporine and mitogen-activated protein kinase kinase inhibitors in human leukemia cells that ectopically express Bcl-2 and Bcl-xL. 61 54
14645670 2003
5
Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins. 61 54
12667137 2003
6
CrmE, a novel soluble tumor necrosis factor receptor encoded by poxviruses. 54 61
11119592 2001
7
Ectromelia, vaccinia and cowpox viruses encode secreted interleukin-18-binding proteins. 61 54
10769064 2000
8
Hepatitis C virus core protein does not inhibit apoptosis in human hepatoma cells. 61 54
10583438 1999
9
Comparison of thymidine kinase and A-type inclusion protein gene sequences from Norwegian and Swedish cowpox virus isolates. 61 54
10440063 1999
10
Uncouplers of oxidative phosphorylation can enhance a Fas death signal. 61 54
10207055 1999
11
Inhibition of human caspases by peptide-based and macromolecular inhibitors. 61 54
9829999 1998
12
A third distinct tumor necrosis factor receptor of orthopoxviruses. 54 61
9520445 1998
13
Caspase-4 and caspase-5, members of the ICE/CED-3 family of cysteine proteases, are CrmA-inhibitable proteases. 54 61
16465268 1997
14
Drug-induced apoptosis is associated with enhanced Fas (Apo-1/CD95) ligand expression but occurs independently of Fas (Apo-1/CD95) signaling in human T-acute lymphatic leukemia cells. 61 54
9269989 1997
15
Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. 61 54
9144192 1997
16
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases. 61 54
8972182 1997
17
Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA. 54 61
8793301 1996
18
Human IL-1 beta processing and secretion in recombinant baculovirus-infected Sf9 cells is blocked by the cowpox virus serpin crmA. 54 61
7868902 1995
19
Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition. 54 61
8034697 1994
20
Patchy Occurrence of Cowpox Virus in Voles from Germany. 61
32013767 2020
21
Early smallpox vaccine manufacturing in the United States: Introduction of the "animal vaccine" in 1870, establishment of "vaccine farms", and the beginnings of the vaccine industry. 61
32473878 2020
22
Harm as a Necessary Component of the Concept of Medical Disorder: Reply to Muckler and Taylor. 61
32437578 2020
23
Sir Matthew Tierney and the foundation of the 1804 Sussex Vaccine Institution. 61
31566102 2020
24
Lumpy skin disease (LSD) outbreaks in cattle in Odisha state, India in August 2019: Epidemiological features and molecular studies. 61
32304275 2020
25
SUCCESSFUL TREATMENT OF CLINICAL ORTHOPOXVIRUS INFECTION IN A GIANT ANTEATER (MYRMECOPHAGA TRIDACTYLA). 61
32212566 2020
26
Three different paths to introduce the smallpox vaccine in early 19th century United States. 61
32057569 2020
27
Poxvirus encoded eIF2α homolog, K3 family proteins, is a key determinant of poxvirus host species specificity. 61
32056708 2020
28
In Vivo Characterization of a Bank Vole-Derived Cowpox Virus Isolate in Natural Hosts and the Rat Model. 61
32093366 2020
29
Field Trial Vaccination against Cowpox in Two Alpaca Herds. 61
32093320 2020
30
What a Difference a Gene Makes: Identification of Virulence Factors of Cowpox Virus. 61
31645446 2020
31
Antibiotics: From the Beginning to the Future: Part 1. 61
31713213 2020
32
Common vole (Microtus arvalis) and bank vole (Myodes glareolus) derived permanent cell lines differ in their susceptibility and replication kinetics of animal and zoonotic viruses. 61
31513859 2019
33
Molecular Detection and Characterization of the First Cowpox Virus Isolate Derived from a Bank Vole. 61
31752129 2019
34
Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation. 61
31575740 2019
35
[Facial necrosis caused by orthopoxvirus : Differential diagnosis and dermatohistopathological correlation of infectious facial ulcers]. 61
31076814 2019
36
Zoonotic Virus Seroprevalence among Bank Voles, Poland, 2002-2010. 61
31310209 2019
37
A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection. 61
30996093 2019
38
Identification of CP77 as the Third Orthopoxvirus SAMD9 and SAMD9L Inhibitor with Unique Specificity for a Rodent SAMD9L. 61
30918078 2019
39
[Human poxvirus infections]. 61
31079914 2019
40
Polyglutamine Repeats in Viruses. 61
30182336 2019
41
CrmA orthologs from diverse poxviruses potently inhibit caspases-1 and -8, yet cleavage site mutagenesis frequently produces caspase-1-specific variants. 61
30992316 2019
42
RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals. 61
30883607 2019
43
Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-Terminal tripeptide of the vaccinia D4 processivity factor. 61
30578797 2019
44
Atypical Cowpox Virus Infection in Smallpox-Vaccinated Patient, France. 61
30666929 2019
45
Preliminary Screening and In Vitro Confirmation of Orthopoxvirus Antivirals. 61
31240676 2019
46
Recombinant Poxviruses: Versatile Tools for Immunological Assays. 61
31147943 2019
47
Cowpox virus infection in two brothers with possible human-to-human transmission. 61
29852532 2019
48
Use of Next Generation Sequencing to study two cowpox virus outbreaks. 61
30847261 2019
49
A System Based-Approach to Examine Cytokine Response in Poxvirus-Infected Macrophages. 61
30563103 2018
50
A standardized approach to the evaluation of antivirals against DNA viruses: Orthopox-, adeno-, and herpesviruses. 61
30287226 2018

Variations for Cowpox

Expression for Cowpox

Search GEO for disease gene expression data for Cowpox.

Pathways for Cowpox

Pathways related to Cowpox according to GeneCards Suite gene sharing:

(show top 50) (show all 72)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.02 TNFRSF1A MX1 KLRK1 KLHL2 IL6 IL18BP
2
Show member pathways
13.88 XIAP TNFRSF1A IL6 FAS EIF2S1 CASP8
3
Show member pathways
13.72 TNFRSF1A IL6 FAS CXCL8 CXCL1 CD80
4
Show member pathways
13.44 XIAP TNFRSF1A IL6 FAS CXCL8 CXCL1
5
Show member pathways
13.4 TNFRSF1A MX1 IL6 IL18BP CXCL8 CXCL1
6
Show member pathways
13.33 TNFRSF1A IL6 GZMB FAS EIF2S1 CXCL8
7
Show member pathways
13.32 TNFRSF1A IL6 FAS CXCL8 CXCL1 CD80
8
Show member pathways
13.19 TNFRSF1A IL6 FAS EIF2S1 CASP8 CASP3
9
Show member pathways
13.13 XIAP TNFRSF1A IL6 FAS CASP8 CASP5
10
Show member pathways
13.08 TNFRSF1A MX1 IL6 FAS EIF2S1 CXCL8
11
Show member pathways
13.02 TNFRSF1A MX1 IL6 FAS CASP8 CASP3
12
Show member pathways
13 TNFRSF1A IL6 FAS CXCL8 CXCL1 CD86
13 12.88 XIAP IL6 FAS CXCL8 CASP8 CASP3
14
Show member pathways
12.87 IL6 GZMB FAS CXCL8 CD8A CD86
15 12.84 TNFRSF1A IL6 FAS EIF2S1 CASP8 CASP3
16
Show member pathways
12.82 TNFRSF1A MX1 IL6 FAS EIF2S1 CXCL8
17 12.8 TNFRSF1A FAS CASP8 CASP3 CASP1
18
Show member pathways
12.8 XIAP GZMB FAS CASP8 CASP3
19
Show member pathways
12.75 IL6 IL18BP CXCL8 CASP5 CASP1
20
Show member pathways
12.73 XIAP FAS CASP8 CASP3 CASP1
21
Show member pathways
12.73 TNFRSF1A GZMB FAS CASP8 CASP3 CASP1
22
Show member pathways
12.71 XIAP TNFRSF1A GZMB FAS EIF2S1 CASP8
23
Show member pathways
12.63 TNFRSF1A FAS CASP8 CASP5 CASP4 CASP3
24
Show member pathways
12.57 XIAP CASP8 CASP5 CASP4 CASP3 CASP1
25 12.43 TNFRSF1A CXCL8 CASP4 CASP1
26
Show member pathways
12.39 IL6 CXCL8 CXCL1 CASP8 CASP3
27
Show member pathways
12.37 TNFRSF1A IL6 CXCL8 CXCL1
28
Show member pathways
12.36 XIAP TNFRSF1A FAS CASP8
29
Show member pathways
12.33 XIAP FAS CASP8 CASP3
30
Show member pathways
12.31 FAS CASP8 CASP5 CASP4 CASP3 CASP1
31 12.3 IL6 GZMB CXCL8 CD86
32
Show member pathways
12.3 XIAP TNFRSF1A CASP8 CASP3
33 12.28 TNFRSF1A IL6 CXCL8 CASP8 CASP5 CASP4
34 12.27 TNFRSF1A IL6 CASP8 CASP3
35
Show member pathways
12.27 XIAP TNFRSF1A FAS CASP8 CASP1
36 12.18 CASP8 CASP5 CASP4 CASP3 CASP1
37 12.17 TNFRSF1A FAS CASP8 CASP3
38 12.14 TNFRSF1A IL6 FAS CXCL8 CASP8 CASP4
39
Show member pathways
12.1 TNFRSF1A CASP8 CASP5 CASP4 CASP3 CASP1
40
Show member pathways
12.08 XIAP GZMB CASP8 CASP3
41 12.07 KLRK1 IL6 CD8A CD86 CD80
42 12.06 IL6 CXCL8 CXCL1 CASP3
43 12.05 TNFRSF1A IL6 FAS CXCL1 CASP8 CASP3
44 12.02 XIAP IL6 CXCL8 CXCL1 CASP8 CASP5
45 12.01 CASP8 CASP5 CASP4 CASP3 CASP1
46 11.99 XIAP TNFRSF1A CXCL8 CXCL1
47 11.98 IL6 CXCL8 CXCL1 CASP3
48 11.95 IL6 CXCL8 CXCL1 CD86 CD80
49
Show member pathways
11.92 IL6 GZMB CD86 CD80
50 11.9 TNFRSF1A CASP3 CASP1

GO Terms for Cowpox

Cellular components related to Cowpox according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 9.77 KLRK1 FAS CD8A CD86 CD80
2 membrane raft GO:0045121 9.73 TNFRSF1A FAS CASP8 CASP3
3 NLRP3 inflammasome complex GO:0072559 9.4 CASP4 CASP1
4 AIM2 inflammasome complex GO:0097169 9.32 CASP4 CASP1
5 CD95 death-inducing signaling complex GO:0031265 9.26 FAS CASP8
6 IPAF inflammasome complex GO:0072557 9.16 CASP4 CASP1
7 NLRP1 inflammasome complex GO:0072558 8.96 CASP5 CASP1
8 death-inducing signaling complex GO:0031264 8.8 FAS CASP8 CASP3

Biological processes related to Cowpox according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.16 TNFRSF1A MX1 KLRK1 IL6 FAS CXCL8
2 proteolysis GO:0006508 10.01 GZMB CASP8 CASP5 CASP4 CASP3 CASP1
3 inflammatory response GO:0006954 9.97 TNFRSF1A IL6 CXCL8 CXCL1 CASP4
4 immune response GO:0006955 9.95 IL6 FAS CXCL8 CXCL1 CD8A CD86
5 cell surface receptor signaling pathway GO:0007166 9.91 TNFRSF1A CD8A CD86 CD80 CASP8
6 regulation of apoptotic process GO:0042981 9.88 FAS CASP8 CASP5 CASP4 CASP1
7 defense response GO:0006952 9.83 TNFRSF1A MX1 CXCL8 CXCL1
8 activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 9.77 FAS CASP8 CASP5 CASP4 CASP1
9 positive regulation of T cell proliferation GO:0042102 9.75 IL6 CD86 CD80
10 regulation of inflammatory response GO:0050727 9.73 XIAP CASP5 CASP4 CASP1
11 T cell costimulation GO:0031295 9.72 KLRK1 CD86 CD80
12 cellular response to mechanical stimulus GO:0071260 9.72 TNFRSF1A FAS CASP8 CASP5 CASP1
13 cellular response to lipopolysaccharide GO:0071222 9.7 KLRK1 IL6 CXCL8 CXCL1 CD86 CD80
14 apoptotic signaling pathway GO:0097190 9.65 FAS CASP8 CASP5 CASP3 CASP1
15 positive regulation of interleukin-2 biosynthetic process GO:0045086 9.61 CD86 CD80
16 PERK-mediated unfolded protein response GO:0036499 9.6 EIF2S1 CXCL8
17 positive regulation of tumor necrosis factor-mediated signaling pathway GO:1903265 9.59 CASP4 CASP1
18 death-inducing signaling complex assembly GO:0071550 9.58 TNFRSF1A CASP8
19 response to cobalt ion GO:0032025 9.56 CASP8 CASP3
20 cytokine-mediated signaling pathway GO:0019221 9.56 TNFRSF1A IL6 CXCL8 CXCL1 CD86 CD80
21 positive regulation of type B pancreatic cell apoptotic process GO:2000676 9.49 IL6 EIF2S1
22 apoptotic process GO:0006915 9.32 XIAP TNFRSF1A MX1 GZMB FAS CASP8

Molecular functions related to Cowpox according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 10.39 XIAP TNFRSF1A MX1 KLRK1 KLHL2 IL6
2 peptidase activity GO:0008233 9.85 GZMB CASP8 CASP5 CASP4 CASP3 CASP1
3 cysteine-type peptidase activity GO:0008234 9.72 CASP8 CASP5 CASP4 CASP3 CASP1
4 cysteine-type endopeptidase activity GO:0004197 9.65 CASP8 CASP5 CASP4 CASP3 CASP1
5 coreceptor activity GO:0015026 9.58 CD8A CD86 CD80
6 cysteine-type endopeptidase activity involved in apoptotic process GO:0097153 9.55 CASP8 CASP5 CASP4 CASP3 CASP1
7 tumor necrosis factor-activated receptor activity GO:0005031 9.46 TNFRSF1A FAS
8 cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0097200 9.35 CASP8 CASP5 CASP4 CASP3 CASP1
9 cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO:0097199 9.02 CASP8 CASP5 CASP4 CASP3 CASP1

Sources for Cowpox

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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