MCID: CRM010
MIFTS: 15

Cramp-Fasciculation Syndrome

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Cramp-Fasciculation Syndrome

MalaCards integrated aliases for Cramp-Fasciculation Syndrome:

Name: Cramp-Fasciculation Syndrome 52
Foley-Denny-Brown Syndrome 71

Classifications:



External Ids:

UMLS 71 C0751381

Summaries for Cramp-Fasciculation Syndrome

NIH Rare Diseases : 52 Cramp-fasciculation syndrome (CFS) is a rare condition of the muscles characterized by persistent muscle cramping and twitching (fasciculations ) in otherwise healthy individuals. This can lead to muscle discomfort, pain, or tiredness. Muscles in the leg are most commonly affected, although this condition may involve several parts of the body. Symptoms are thought to be due to over-activity of the associated nerves. In most cases, CFS occurs sporadically in people with no family history of the condition. There is limited information about the treatment of CFS, but certain medications have been reported as beneficial in individual cases.

MalaCards based summary : Cramp-Fasciculation Syndrome, also known as foley-denny-brown syndrome, is related to seizures, benign familial neonatal, 1 and episodic ataxia. An important gene associated with Cramp-Fasciculation Syndrome is GLA (Galactosidase Alpha). Affiliated tissues include t cells.

Wikipedia : 74 Cramp fasciculation syndrome (CFS) is a rare peripheral nerve hyperexcitability disorder. It is more... more...

Related Diseases for Cramp-Fasciculation Syndrome

Graphical network of the top 20 diseases related to Cramp-Fasciculation Syndrome:



Diseases related to Cramp-Fasciculation Syndrome

Symptoms & Phenotypes for Cramp-Fasciculation Syndrome

Drugs & Therapeutics for Cramp-Fasciculation Syndrome

Search Clinical Trials , NIH Clinical Center for Cramp-Fasciculation Syndrome

Genetic Tests for Cramp-Fasciculation Syndrome

Anatomical Context for Cramp-Fasciculation Syndrome

MalaCards organs/tissues related to Cramp-Fasciculation Syndrome:

40
T Cells

Publications for Cramp-Fasciculation Syndrome

Articles related to Cramp-Fasciculation Syndrome:

(show all 42)
# Title Authors PMID Year
1
A novel TRPA1 variant is associated with carbamazepine-responsive cramp-fasciculation syndrome. 61 52
28436534 2018
2
Cramp-fasciculation syndrome in patients with and without neural autoantibodies. 61 52
23836298 2014
3
Accuracy of repetitive nerve stimulation for diagnosis of the cramp-fasciculation syndrome. 61 52
17405138 2007
4
Episodic Muscle Disorders. 61
31794467 2019
5
Peripheral nerve hyperexcitability. 61
31307606 2019
6
Successful Improvement of Pain Symptomatology in a Suspected Case of Cramp-Fasciculation Syndrome via Interventional Pain Treatment. 61
29775120 2018
7
Cramp-fasciculation syndrome associated with monofocal motor neuropathy. 61
28006835 2017
8
Peripheral Nerve Hyperexcitability Syndromes. 61
28968370 2017
9
Clinical, Electrophysiological, and Serological Evaluation of Patients with Cramp-Fasciculation Syndrome. 61
28680318 2017
10
Afterdischarges following M waves in patients with voltage-gated potassium channels antibodies. 61
30214975 2017
11
Increased HCN channel driven inward rectification in benign cramp fasciculation syndrome. 61
26342125 2015
12
Abnormal gating of axonal slow potassium current in cramp-fasciculation syndrome. 61
25304174 2015
13
Fasciculations in human hereditary disease. 61
25073774 2015
14
Peripheral nerve hyperexcitability syndromes. 61
25719304 2015
15
[Epidemiology, clinical spectrum of ALS and differential diagnoses]. 61
24703738 2014
16
[An autopsy case of amyotrophic lateral sclerosis with prominent muscle cramps, fasciculation, and high titer of anti-voltage gated potassium channel (VGKC) complex antibody]. 61
24429646 2014
17
Cramps and small-fiber neuropathy. 61
23813593 2013
18
Fasciculation anxiety syndrome in clinicians. 61
23400500 2013
19
[Management of muscle cramp: what's to be done?]. 61
23789484 2013
20
Kinesigenic dyskinesia in a case of voltage-gated potassium channel-complex protein antibody encephalitis. 61
21149804 2011
21
Fasciculation-cramp syndrome preceding anterior horn cell disease: an intermediate syndrome? 61
20587485 2011
22
[Anti-VGKC antibody-associated limbic encephalitis/Morvan syndrome]. 61
20420173 2010
23
Defining normal duration for afterdischarges with repetitive nerve stimulation: a pilot study. 61
19151616 2009
24
Postirradiation localized cramp-fasciculation syndrome. 61
16864803 2006
25
Later-onset Fabry disease: an adult variant presenting with the cramp-fasciculation syndrome. 61
16533976 2006
26
Bronchial involvement in the cramp-fasciculation syndrome. 61
16960453 2006
27
Clinical aspects of neuromuscular transmission disorders. 61
16637919 2006
28
Neuromuscular junction channelopathies: a brief overview. 61
16482866 2005
29
[Cramp-fasciculation syndrome]. 61
16340924 2005
30
Neuromyotonia. 61
15269665 2004
31
Autoimmune disorders of neuronal potassium channels. 61
14592877 2003
32
Ion channel and striational antibodies define a continuum of autoimmune neuromuscular hyperexcitability. 61
12402293 2002
33
Phenotypic variants of autoimmune peripheral nerve hyperexcitability. 61
12135978 2002
34
Excitability properties of motor axons in patients with spontaneous motor unit activity. 61
11118248 2001
35
Myasthenia, thymoma, presynaptic antibodies, and a continuum of neuromuscular hyperexcitability. 61
10522878 1999
36
Involvement of the esophagus in the cramp-fasciculation syndrome. 61
9585337 1998
37
Botulinum toxin treatment of muscle cramps: a clinical and neurophysiological study. 61
9029067 1997
38
[Muscle cramps and fasciculations not always ominous: muscle cramp-fasciculation syndrome]. 61
8815407 1996
39
Cramp-fasciculation syndrome. 61
1513486 1992
40
Cramp-fasciculation syndrome. 61
1310534 1992
41
Cramp-fasciculation syndrome: a treatable hyperexcitable peripheral nerve disorder. 61
1648679 1991
42
Estimation of the frequency of the muscular pain-fasciculation syndrome and the muscular cramp-fasciculation syndrome in the adult population. 61
1834178 1991

Variations for Cramp-Fasciculation Syndrome

Expression for Cramp-Fasciculation Syndrome

Search GEO for disease gene expression data for Cramp-Fasciculation Syndrome.

Pathways for Cramp-Fasciculation Syndrome

GO Terms for Cramp-Fasciculation Syndrome

Sources for Cramp-Fasciculation Syndrome

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68 SNOMED-CT via HPO
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70 Tocris
71 UMLS
72 UMLS via Orphanet
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