MCID: CRM010
MIFTS: 14

Cramp-Fasciculation Syndrome

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Cramp-Fasciculation Syndrome

MalaCards integrated aliases for Cramp-Fasciculation Syndrome:

Name: Cramp-Fasciculation Syndrome 54
Foley-Denny-Brown Syndrome 74

Classifications:



External Ids:

UMLS 74 C0751381

Summaries for Cramp-Fasciculation Syndrome

NIH Rare Diseases : 54 Cramp-fasciculation syndrome (CFS) is a rare condition of the muscles characterized by persistent muscle cramping and twitching (fasciculations) in otherwise healthy individuals. This can lead to muscle discomfort, pain, or tiredness. Muscles in the leg are most commonly affected, although this condition may involve several parts of the body. Symptoms are thought to be due to over-activity of the associated nerves. In most cases, CFS occurs sporadically in people with no family history of the condition. There is limited information about the treatment of CFS, but certain medications have been reported as beneficial in individual cases.

MalaCards based summary : Cramp-Fasciculation Syndrome, also known as foley-denny-brown syndrome, is related to fabry disease and neuropathy. An important gene associated with Cramp-Fasciculation Syndrome is GLA (Galactosidase Alpha).

Wikipedia : 77 Cramp fasciculation syndrome (CFS) is a rare peripheral nerve hyperexcitability disorder. It is more... more...

Related Diseases for Cramp-Fasciculation Syndrome

Diseases related to Cramp-Fasciculation Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 fabry disease 10.2
2 neuropathy 10.2

Symptoms & Phenotypes for Cramp-Fasciculation Syndrome

Drugs & Therapeutics for Cramp-Fasciculation Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Serial Fasciculation Measurements in Motor Neurone Disease Active, not recruiting NCT03809845 Not Applicable

Search NIH Clinical Center for Cramp-Fasciculation Syndrome

Genetic Tests for Cramp-Fasciculation Syndrome

Anatomical Context for Cramp-Fasciculation Syndrome

Publications for Cramp-Fasciculation Syndrome

Articles related to Cramp-Fasciculation Syndrome:

(show all 16)
# Title Authors Year
1
A novel TRPA1 variant is associated with carbamazepine-responsive cramp-fasciculation syndrome. ( 28436534 )
2018
2
Successful Improvement of Pain Symptomatology in a Suspected Case of Cramp-Fasciculation Syndrome via Interventional Pain Treatment. ( 29775120 )
2018
3
Cramp-fasciculation syndrome associated with monofocal motor neuropathy. ( 28006835 )
2017
4
Clinical, Electrophysiological, and Serological Evaluation of Patients with Cramp-Fasciculation Syndrome. ( 28680318 )
2017
5
Abnormal gating of axonal slow potassium current in cramp-fasciculation syndrome. ( 25304174 )
2015
6
Increased HCN channel driven inward rectification in benign cramp fasciculation syndrome. ( 26342125 )
2015
7
Cramp-fasciculation syndrome in patients with and without neural autoantibodies. ( 23836298 )
2014
8
Accuracy of repetitive nerve stimulation for diagnosis of the cramp-fasciculation syndrome. ( 17405138 )
2007
9
Later-onset Fabry disease: an adult variant presenting with the cramp-fasciculation syndrome. ( 16533976 )
2006
10
Postirradiation localized cramp-fasciculation syndrome. ( 16864803 )
2006
11
Bronchial involvement in the cramp-fasciculation syndrome. ( 16960453 )
2006
12
Involvement of the esophagus in the cramp-fasciculation syndrome. ( 9585337 )
1998
13
Cramp-fasciculation syndrome. ( 1310534 )
1992
14
Cramp-fasciculation syndrome. ( 1513486 )
1992
15
Cramp-fasciculation syndrome: a treatable hyperexcitable peripheral nerve disorder. ( 1648679 )
1991
16
Estimation of the frequency of the muscular pain-fasciculation syndrome and the muscular cramp-fasciculation syndrome in the adult population. ( 1834178 )
1991

Variations for Cramp-Fasciculation Syndrome

Expression for Cramp-Fasciculation Syndrome

Search GEO for disease gene expression data for Cramp-Fasciculation Syndrome.

Pathways for Cramp-Fasciculation Syndrome

GO Terms for Cramp-Fasciculation Syndrome

Sources for Cramp-Fasciculation Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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