Cranial Nerve Malignant Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Cranial Nerve Malignant Neoplasm

MalaCards integrated aliases for Cranial Nerve Malignant Neoplasm:

Name: Cranial Nerve Malignant Neoplasm ¹² ¹⁵ ¹⁷

Cranial Nerve Neoplasms ⁴³ ⁷¹

Malignant Neoplasm of Cranial Nerves ¹²

Malignant Tumor of the Cranial Nerve ¹²

Malignant Neoplasm of Cranial Nerve ¹²

Malignant Tumor of Cranial Nerve ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:2815

ICD9CM ³⁴ 192.0

MeSH ⁴³ D003390

NCIt ⁴⁹ C3571

SNOMED-CT ⁶⁷ 93767009

ICD10 ³² C72.50

EFO ¹⁷ EFO_1000884

UMLS ⁷¹ C0010267 C0153644

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Summaries for Cranial Nerve Malignant Neoplasm

MalaCards based summary : Cranial Nerve Malignant Neoplasm, also known as cranial nerve neoplasms, is related to hydrocephalus and cranial nerve neoplasm. An important gene associated with Cranial Nerve Malignant Neoplasm is ENO2 (Enolase 2), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include lung, pituitary and kidney, and related phenotypes are behavior/neurological and nervous system

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Related Diseases for Cranial Nerve Malignant Neoplasm

Diseases related to Cranial Nerve Malignant Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 317)

#	Related Disease	Score	Top Affiliating Genes
1	hydrocephalus	29.6	SYP SMARCB1 GFAP ENO2
2	cranial nerve neoplasm	29.6	SYP SMARCB1 POMC OMP NUTM1 NCAM1
3	malignant oculomotor nerve tumor	11.4
4	malignant melanocytic neoplasm of the peripheral nerve sheath	10.6	SYP ENO2
5	sinonasal undifferentiated carcinoma	10.6	SYP ENO2
6	papillary tumor of the pineal region	10.6	SYP ENO2
7	bile duct mucinous adenocarcinoma	10.6	SYP ENO2
8	nodular prostate	10.6	SYP ENO2
9	cloacogenic carcinoma	10.5	SYP ENO2
10	vaginal glandular tumor	10.5	ENO2 CHGA
11	primary hepatic neuroendocrine carcinoma	10.5	SYP CHGA
12	cerebellar liponeurocytoma	10.5	SYP ENO2
13	acinar cell cystadenocarcinoma	10.5	SYP CHGA
14	retroperitoneal neuroblastoma	10.5	ENO2 CD99
15	vulvar eccrine porocarcinoma	10.5	SYP CHGA
16	gastrointestinal neuroendocrine benign tumor	10.5	SYP CHGA
17	gastric gastrinoma	10.5	ENO2 CHGA
18	optic nerve astrocytoma	10.5	SYP ENO2
19	mixed ductal-endocrine carcinoma	10.5	SYP CHGA
20	goblet cell carcinoid	10.5	ENO2 CHGA
21	breast papillary carcinoma	10.5	SYP CHGA
22	frontal lobe neoplasm	10.5	SYP ENO2
23	vaginal tubulovillous adenoma	10.5	SYP CHGA
24	pineal parenchymal tumor of intermediate differentiation	10.5	SYP ENO2
25	vaginal adenoma	10.5	SYP CHGA
26	hypoganglionosis	10.5	SYP NCAM1
27	gastric neuroendocrine neoplasm	10.5	SYP CHGA
28	vaginal benign neoplasm	10.5	SYP CHGA
29	extraskeletal mesenchymal chondrosarcoma	10.5	EWSR1 CD99
30	liver leiomyosarcoma	10.5	ENO2 CHGA
31	pancreatic gastrinoma	10.5	SYP CHGA
32	gastrointestinal neuroendocrine tumor	10.5	SYP CHGA
33	lymphocytic hypophysitis	10.5	POMC ENO2
34	testicular granulosa cell tumor	10.5	MLANA CD99
35	orbital cancer	10.5	NCAM1 ENO2
36	lung clear cell carcinoma	10.5	SYP CHGA
37	penis sarcoma	10.5	MLANA ENO2
38	cellular ependymoma	10.5	SYP CD99
39	pancreatic acinar cell adenocarcinoma	10.4	SYP CHGA
40	biliary tract benign neoplasm	10.4	SYP NCAM1
41	extra-adrenal pheochromocytoma	10.4	SYP CHGA
42	intracranial primitive neuroectodermal tumor	10.4	SYP ENO2 CD99
43	glomangiosarcoma	10.4	SYP MLANA
44	small cell carcinoma of the bladder	10.4	SYP ENO2 CHGA
45	appendix carcinoid tumor	10.4	SYP ENO2 CHGA
46	auditory system cancer	10.4	SYP ENO2 CHGA
47	thymus small cell carcinoma	10.4	SYP ENO2 CHGA
48	duodenal benign neoplasm	10.4	SYP ENO2 CHGA
49	ampulla of vater neoplasm	10.4	SYP ENO2 CHGA
50	middle ear adenoma	10.4	SYP ENO2 CHGA

Graphical network of the top 20 diseases related to Cranial Nerve Malignant Neoplasm:

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Symptoms & Phenotypes for Cranial Nerve Malignant Neoplasm

MGI Mouse Phenotypes related to Cranial Nerve Malignant Neoplasm:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	9.85	AVP ENO2 GFAP MYOG NCAM1 OMP
2	nervous system	MP:0003631	9.65	AVP CHGA ENO2 GFAP NCAM1 OMP
3	no phenotypic analysis	MP:0003012	9.17	AVP CHGA MLANA MYOG OMP POMC

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Drugs & Therapeutics for Cranial Nerve Malignant Neoplasm

Search Clinical Trials , NIH Clinical Center for Cranial Nerve Malignant Neoplasm

Cochrane evidence based reviews: cranial nerve neoplasms

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Genetic Tests for Cranial Nerve Malignant Neoplasm

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Anatomical Context for Cranial Nerve Malignant Neoplasm

MalaCards organs/tissues related to Cranial Nerve Malignant Neoplasm:

⁴⁰

Lung, Pituitary, Kidney, Breast, Ovary, Prostate, Pineal

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Publications for Cranial Nerve Malignant Neoplasm

Articles related to Cranial Nerve Malignant Neoplasm:

#	Title	Authors	PMID	Year
1	Predicting Readmission and Reoperation for Benign Cranial Nerve Neoplasms: A Nationwide Analysis. ⁶¹	Gupta S...Smith TR	30261394	2019
2	Morbid obesity increases risk of morbidity and reoperation in resection of benign cranial nerve neoplasms. ⁶¹	Murphy ME...Link MJ	27434528	2016
3	Is Patient Age Associated with Perioperative Outcomes After Surgical Resection of Benign Cranial Nerve Neoplasms? ⁶¹	McCutcheon BA...Mayo Clinic Neuro-Informatics Laboratory	26855306	2016
4	The Relation between Obesity and Hospital Length of Stay after Elective Lateral Skull Base Surgery: An Analysis of the American College of Surgeons National Surgical Quality Improvement Program. ⁶¹	O'Connell BP...Meyer TA	26360829	2015
5	MR imaging of primary trochlear nerve neoplasms. ⁶¹	Gentry LR...Weinstein JM	1882749	1991

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Genes for Cranial Nerve Malignant Neoplasm

Genes related to Cranial Nerve Malignant Neoplasm (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ENO2	Enolase 2	Protein Coding	7.86	DISEASES inferred ¹⁵
2	SYP	Synaptophysin	Protein Coding	7.77	DISEASES inferred ¹⁵
3	CD99	CD99 Molecule (Xg Blood Group)	Protein Coding	7.09	DISEASES inferred ¹⁵
4	CHGA	Chromogranin A	Protein Coding	6.63	DISEASES inferred ¹⁵
5	AVP	Arginine Vasopressin	Protein Coding	6.58	DISEASES inferred ¹⁵
6	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	6.53	DISEASES inferred ¹⁵
7	EWSR1	EWS RNA Binding Protein 1	Protein Coding	6.52	DISEASES inferred ¹⁵
8	CCDC54	Coiled-Coil Domain Containing 54	Protein Coding	6.26	DISEASES inferred ¹⁵
9	OMP	Olfactory Marker Protein	Protein Coding	6.13	DISEASES inferred ¹⁵
10	POMC	Proopiomelanocortin	Protein Coding	6.12	DISEASES inferred ¹⁵
11	MLANA	Melan-A	Protein Coding	5.94	DISEASES inferred ¹⁵
12	NUTM1	NUT Midline Carcinoma Family Member 1	Protein Coding	5.77	DISEASES inferred ¹⁵
13	MYOG	Myogenin	Protein Coding	5.62	DISEASES inferred ¹⁵
14	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	5.6	DISEASES inferred ¹⁵
15	SMARCB1	SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily B, Member 1	Protein Coding	5.53	DISEASES inferred ¹⁵
16	SERPINB3	Serpin Family B Member 3	Protein Coding	5.51	DISEASES inferred ¹⁵
17	PTPRC	Protein Tyrosine Phosphatase Receptor Type C	Protein Coding	5.51	DISEASES inferred ¹⁵

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Variations for Cranial Nerve Malignant Neoplasm

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Expression for Cranial Nerve Malignant Neoplasm

Search GEO for disease gene expression data for Cranial Nerve Malignant Neoplasm.

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Pathways for Cranial Nerve Malignant Neoplasm

Pathways related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ⁴	11.63	SYP POMC NCAM1 GFAP ENO2 AVP
2	Neural Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.03	SYP NCAM1 GFAP

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GO Terms for Cranial Nerve Malignant Neoplasm

Cellular components related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	secretory granule	GO:0030141	8.8	POMC CHGA AVP

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Sources for Cranial Nerve Malignant Neoplasm

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