MCID: CRN033
MIFTS: 26

Cranial Nerve Malignant Neoplasm

Categories: Cancer diseases, Neuronal diseases
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Aliases & Classifications for Cranial Nerve Malignant Neoplasm

MalaCards integrated aliases for Cranial Nerve Malignant Neoplasm:

Name: Cranial Nerve Malignant Neoplasm 11 14 16
Cranial Nerve Neoplasms 43 71
Malignant Tumor of the Cranial Nerve 11
Malignant Neoplasm of Cranial Nerve 11
Malignant Tumor of Cranial Nerve 11

Classifications:



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Disease Ontology 11 DOID:2815
ICD9CM 34 192.0
MeSH 43 D003390
NCIt 49 C2963 C3571
SNOMED-CT 68 126966009 188311003
UMLS 71 C0010267 C0153644

Summaries for Cranial Nerve Malignant Neoplasm

Disease Ontology: 11 A central nervous system cancer that affects a cranial nerve, develops from schwann cells located in cranial nerves, has material basis in abnormally proliferating cells.

MalaCards based summary: Cranial Nerve Malignant Neoplasm, also known as cranial nerve neoplasms, is related to hydrocephalus and neurilemmoma. An important gene associated with Cranial Nerve Malignant Neoplasm is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Neuroscience and Sudden infant death syndrome (SIDS) susceptibility pathways. Affiliated tissues include cranial nerves, and related phenotypes are Increased proliferation and nervous system

Related Diseases for Cranial Nerve Malignant Neoplasm

Diseases related to Cranial Nerve Malignant Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 434)
# Related Disease Score Top Affiliating Genes
1 hydrocephalus 29.9 SYP SMARCB1 NCAM1 GFAP ENO2
2 neurilemmoma 29.0 SYP SMARCB1 NF2 NF1 MLANA MIR409
3 vagus nerve neoplasm 10.4 SYP NF1
4 malignant melanocytic neoplasm of the peripheral nerve sheath 10.4 SYP ENO2
5 lumbosacral plexus lesion 10.4 SYP NF1
6 neuronal intestinal dysplasia, type b 10.4 SYP ENO2
7 pacinian tumor 10.4 NF1 ENO2
8 epithelioid neurofibroma 10.4 NF2 NF1
9 cloacogenic carcinoma 10.4 SYP ENO2
10 lung meningioma 10.4 SYP NF2
11 bile duct mucinous adenocarcinoma 10.4 SYP ENO2
12 myocardium cancer 10.4 SYP CD99
13 cerebellar liponeurocytoma 10.4 SYP ENO2
14 frontal lobe neoplasm 10.4 SYP ENO2
15 lipoma of spermatic cord 10.4 SYP ENO2
16 jejunal neoplasm 10.4 SYP ENO2
17 neurilemmoma of the fifth cranial nerve 10.4 NF2 NF1
18 trigeminal nerve neoplasm 10.4 NF2 NF1
19 paratesticular lipoma 10.4 SYP ENO2
20 pancreas lymphoma 10.4 SYP CHGA
21 vaginal glandular tumor 10.4 ENO2 CHGA
22 vaginal tubulovillous adenoma 10.4 SYP CHGA
23 prostate small cell carcinoma 10.4 SYP ENO2
24 mixed ductal-endocrine carcinoma 10.4 SYP CHGA
25 vulvar eccrine porocarcinoma 10.4 SYP CHGA
26 cervical large cell neuroendocrine carcinoma 10.4 SYP CHGA
27 subungual glomus tumor 10.4 SYP NF1
28 acinar cell cystadenocarcinoma 10.4 SYP CHGA
29 meninges hemangiopericytoma 10.4 NF2 CD99
30 goblet cell carcinoid 10.4 ENO2 CHGA
31 full schwannomatosis 10.4 SMARCB1 NF2
32 breast papillary carcinoma 10.4 SYP CHGA
33 myoblastoma 10.4 SYP ENO2
34 spinal cord astrocytoma 10.4 NF2 NF1
35 ovarian mucinous cystadenofibroma 10.4 SYP NCAM1
36 ovarian mucinous adenofibroma 10.4 SYP NCAM1
37 mucinous adenofibroma 10.4 SYP NCAM1
38 posterior pituitary gland neoplasm 10.3 SMARCB1 NF2
39 skin granular cell tumor 10.3 NF1 ENO2
40 childhood meningioma 10.3 SMARCB1 NF2
41 cerebral falx meningioma 10.3 SMARCB1 NF2
42 parasagittal meningioma 10.3 SMARCB1 NF2
43 parachordoma 10.3 EWSR1 ENO2
44 cerebral convexity meningioma 10.3 SMARCB1 NF2
45 mechanical ectropion 10.3 NF1 NCAM1
46 breast granular cell tumor 10.3 NCAM1 ENO2
47 schwannomatosis 1 10.3 SMARCB1 NF2
48 olfactory groove meningioma 10.3 SMARCB1 NF2
49 cerebellopontine angle tumor 10.3 SMARCB1 NF2
50 horner's syndrome 10.3 SYP NF1 ENO2

Graphical network of the top 20 diseases related to Cranial Nerve Malignant Neoplasm:



Diseases related to Cranial Nerve Malignant Neoplasm

Symptoms & Phenotypes for Cranial Nerve Malignant Neoplasm

GenomeRNAi Phenotypes related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Cranial Nerve Malignant Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 10 AVP CHGA ENO2 GFAP NCAM1 NF1
2 growth/size/body region MP:0005378 9.77 CHGA ENO2 EWSR1 GFAP NF1 NF2
3 behavior/neurological MP:0005386 9.44 AVP ENO2 EWSR1 GFAP NCAM1 NF1

Drugs & Therapeutics for Cranial Nerve Malignant Neoplasm

Search Clinical Trials, NIH Clinical Center for Cranial Nerve Malignant Neoplasm

Cochrane evidence based reviews: cranial nerve neoplasms

Genetic Tests for Cranial Nerve Malignant Neoplasm

Anatomical Context for Cranial Nerve Malignant Neoplasm

Organs/tissues related to Cranial Nerve Malignant Neoplasm:

FMA: Cranial Nerves

Publications for Cranial Nerve Malignant Neoplasm

Variations for Cranial Nerve Malignant Neoplasm

Expression for Cranial Nerve Malignant Neoplasm

Search GEO for disease gene expression data for Cranial Nerve Malignant Neoplasm.

Pathways for Cranial Nerve Malignant Neoplasm

Pathways related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.81 SYP POMC NKX2-2 NF2 NF1 NCAM1
2 11.66 SSTR2 SST NKX2-2 AVP
3 11.15 SYP NKX2-2 NCAM1 GFAP

GO Terms for Cranial Nerve Malignant Neoplasm

Cellular components related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal dense core vesicle GO:0098992 8.92 SST CHGA AVP

Biological processes related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of Schwann cell proliferation GO:0010626 9.26 NF2 NF1
2 Schwann cell proliferation GO:0014010 9.1 NF2 NF1 GFAP

Sources for Cranial Nerve Malignant Neoplasm

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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