Cranial Nerve Malignant Neoplasm disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Cranial Nerve Malignant Neoplasm

MalaCards integrated aliases for Cranial Nerve Malignant Neoplasm:

Name: Cranial Nerve Malignant Neoplasm ¹² ¹⁵

Cranial Nerve Neoplasms ⁴⁴ ⁷³

Cranial Nerve Neoplasm ¹² ¹⁵

Malignant Neoplasm of Cranial Nerves ¹²

Malignant Tumor of the Cranial Nerve ¹²

Malignant Neoplasm of Cranial Nerve ¹²

Malignant Tumor of Cranial Nerve ¹²

Tumor of the Cranial Nerve ¹²

Neoplasm of Cranial Nerve ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:2815 DOID:338

ICD10 ³³ C72.50

ICD9CM ³⁵ 192.0

MeSH ⁴⁴ D003390

NCIt ⁵⁰ C3571 C2963

SNOMED-CT ⁶⁸ 93767009

UMLS ⁷³ C0153644 C0010267

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Summaries for Cranial Nerve Malignant Neoplasm

Disease Ontology : ¹² A central nervous system cancer develops from schwann cells located in cranial nerves, has material basis in abnormally proliferating cells.

MalaCards based summary : Cranial Nerve Malignant Neoplasm, also known as cranial nerve neoplasms, is related to malignant oculomotor nerve tumor and chondroid chordoma. An important gene associated with Cranial Nerve Malignant Neoplasm is TUBB3 (Tubulin Beta 3 Class III), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include lung, brain and ovary, and related phenotypes are nervous system and taste/olfaction

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Related Diseases for Cranial Nerve Malignant Neoplasm

Diseases related to Cranial Nerve Malignant Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 183)

#	Related Disease	Score	Top Affiliating Genes
1	malignant oculomotor nerve tumor	11.2
2	chondroid chordoma	10.3	ENO2 TUBB3
3	chondrosarcoma, extraskeletal myxoid	10.3	ENO2 SYP
4	central nervous system benign neoplasm	10.3	ENO2 SYP
5	mixed cell type cancer	10.3	ENO2 SYP
6	cystic teratoma	10.3	ENO2 SYP
7	optic nerve neoplasm	10.3	ENO2 SYP
8	medullomyoblastoma	10.3	ENO2 SYP
9	optic nerve glioma	10.3	ENO2 SYP
10	subependymal giant cell astrocytoma	10.3	ENO2 SYP
11	basaloid squamous cell carcinoma	10.3	ENO2 SYP
12	cerebral primitive neuroectodermal tumor	10.3	ENO2 SYP
13	tracheal cancer	10.2	AVP ENO2
14	nervous system benign neoplasm	10.2	ENO2 SYP
15	ganglioneuroblastoma	10.2	ENO2 SYP
16	carotid body cancer	10.2	ENO2 SYP
17	malignant sertoli cell tumor	10.2	ENO2 SYP
18	sinonasal undifferentiated carcinoma	10.2	ENO2 SYP
19	ovarian carcinosarcoma	10.2	SYP TUBB3
20	pancreatic somatostatinoma	10.2	ENO2 SYP
21	papillary tumor of the pineal region	10.2	ENO2 SYP
22	sensory organ benign neoplasm	10.2	ENO2 SYP
23	spinal meningioma	10.2	CHGA ENO2
24	spinal canal and spinal cord meningioma	10.2	CHGA ENO2
25	middle ear adenoma	10.2	ENO2 SYP
26	diffuse pulmonary fibrosis	10.2	CHGA ENO2
27	central nervous system primitive neuroectodermal neoplasm	10.2	ENO2 SYP
28	cerebellum cancer	10.2	ENO2 SYP
29	clear cell ependymoma	10.2	ENO2 SYP
30	tubular adenocarcinoma	10.2	CHGA SYP
31	gastric tubular adenocarcinoma	10.2	CHGA SYP
32	cerebral neuroblastoma	10.2	ENO2 SYP
33	binswanger's disease	10.2	CHGA SYP
34	extraosseous chondrosarcoma	10.2	ENO2 SYP
35	subependymal glioma	10.2	ENO2 SYP
36	astroblastoma	10.2	ENO2 SYP
37	cystadenoma	10.2	CHGA SYP
38	cerebral ventricle cancer	10.2	ENO2 SYP
39	mixed type thymoma	10.2	AVP SYP
40	ileum cancer	10.2	ENO2 NCAM1
41	melanotic neuroectodermal tumor	10.2	ENO2 SYP
42	intracranial primitive neuroectodermal tumor	10.2	CHGA ENO2
43	cloacogenic carcinoma	10.2	ENO2 POMC
44	benign ependymoma	10.2	ENO2 SYP
45	ureter small cell carcinoma	10.2	CHGA SYP
46	adrenal insufficiency, congenital, with 46,xy sex reversal, partial or complete	10.2	POMC SYP
47	adrenal cortical adenoma	10.2	POMC SYP
48	ectopic cushing syndrome	10.2	POMC SYP
49	sex cord-gonadal stromal tumor	10.2	POMC SYP
50	somatostatinoma	10.2	CHGA ENO2

Graphical network of the top 20 diseases related to Cranial Nerve Malignant Neoplasm:

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Symptoms & Phenotypes for Cranial Nerve Malignant Neoplasm

MGI Mouse Phenotypes related to Cranial Nerve Malignant Neoplasm:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	nervous system	MP:0003631	9.61	AVP CHGA CNGA2 ENO2 NCAM1 OMP
2	taste/olfaction	MP:0005394	8.8	CNGA2 ENO2 OMP

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Drugs & Therapeutics for Cranial Nerve Malignant Neoplasm

Search Clinical Trials , NIH Clinical Center for Cranial Nerve Malignant Neoplasm

Cochrane evidence based reviews: cranial nerve neoplasms

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Genetic Tests for Cranial Nerve Malignant Neoplasm

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Anatomical Context for Cranial Nerve Malignant Neoplasm

MalaCards organs/tissues related to Cranial Nerve Malignant Neoplasm:

⁴¹

Lung, Brain, Ovary, Pituitary, Pancreas, Thyroid, Pineal

The Foundational Model of Anatomy Ontology organs/tissues related to Cranial Nerve Malignant Neoplasm:

¹⁹

Cranial Nerves

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Publications for Cranial Nerve Malignant Neoplasm

Articles related to Cranial Nerve Malignant Neoplasm:

#	Title	Authors	Year
1	Predicting Readmission and Reoperation for Benign Cranial Nerve Neoplasms: A Nationwide Analysis. ( 30261394 )	Gupta S...Smith TR	2018
2	Morbid obesity increases risk of morbidity and reoperation in resection of benign cranial nerve neoplasms. ( 27434528 )	Murphy M.E....Link M.J.	2016
3	Is Patient Age Associated with Perioperative Outcomes After Surgical Resection of Benign Cranial Nerve Neoplasms? ( 26855306 )	McCutcheon BA...Mayo Clinic Neuro-Informatics Laboratory	2016

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Genes for Cranial Nerve Malignant Neoplasm

Genes related to Cranial Nerve Malignant Neoplasm (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	TUBB3	Tubulin Beta 3 Class III	Protein Coding	26.39	DISEASES inferred ¹⁵ ¹⁵ ¹⁵ ¹⁵
2	ENO2	Enolase 2	Protein Coding	24.04	DISEASES inferred ¹⁵ ¹⁵
3	SYP	Synaptophysin	Protein Coding	23.06	DISEASES inferred ¹⁵ ¹⁵
4	AVP	Arginine Vasopressin	Protein Coding	21.89	DISEASES inferred ¹⁵ ¹⁵
5	OMP	Olfactory Marker Protein	Protein Coding	21.89	DISEASES inferred ¹⁵ ¹⁵
6	CHGA	Chromogranin A	Protein Coding	21.04	DISEASES inferred ¹⁵ ¹⁵
7	POMC	Proopiomelanocortin	Protein Coding	20.18	DISEASES inferred ¹⁵ ¹⁵
8	CNGA2	Cyclic Nucleotide Gated Channel Alpha 2	Protein Coding	20.05	DISEASES inferred ¹⁵ ¹⁵
9	RASA2	RAS P21 Protein Activator 2	Protein Coding	19.86	DISEASES inferred ¹⁵ ¹⁵
10	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	19.61	DISEASES inferred ¹⁵ ¹⁵

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Variations for Cranial Nerve Malignant Neoplasm

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Expression for Cranial Nerve Malignant Neoplasm

Search GEO for disease gene expression data for Cranial Nerve Malignant Neoplasm.

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Pathways for Cranial Nerve Malignant Neoplasm

Pathways related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ⁴	11.63	AVP ENO2 NCAM1 POMC SYP TUBB3

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GO Terms for Cranial Nerve Malignant Neoplasm

Cellular components related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	secretory granule	GO:0030141	8.8	AVP CHGA POMC

Biological processes related to Cranial Nerve Malignant Neoplasm according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	generation of precursor metabolites and energy	GO:0006091	8.62	AVP POMC

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Sources for Cranial Nerve Malignant Neoplasm

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