MCID: CRN034
MIFTS: 26

Cranial Nerve Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cranial Nerve Neoplasm

MalaCards integrated aliases for Cranial Nerve Neoplasm:

Name: Cranial Nerve Neoplasm 12 15
Neoplasm of Cranial Nerve 12

Classifications:



External Ids:

Disease Ontology 12 DOID:338
MeSH 43 D003390
NCIt 49 C2963
UMLS 71 C0010267

Summaries for Cranial Nerve Neoplasm

Disease Ontology : 12 A central nervous system cancer develops from schwann cells located in cranial nerves, has material basis in abnormally proliferating cells.

MalaCards based summary : Cranial Nerve Neoplasm, also known as neoplasm of cranial nerve, is related to hydrocephalus and cranial nerve malignant neoplasm. An important gene associated with Cranial Nerve Neoplasm is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Neuroscience and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include cranial nerves, lung and prostate, and related phenotypes are Increased proliferation and behavior/neurological

Related Diseases for Cranial Nerve Neoplasm

Diseases related to Cranial Nerve Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 348)
# Related Disease Score Top Affiliating Genes
1 hydrocephalus 30.1 SYP SMARCB1 GFAP ENO2
2 cranial nerve malignant neoplasm 28.3 SYP SMARCB1 POMC OMP NUTM1 NCAM1
3 malignant oculomotor nerve tumor 11.4
4 malignant melanocytic neoplasm of the peripheral nerve sheath 10.6 SYP ENO2
5 pacinian tumor 10.6 NF1 ENO2
6 sinonasal undifferentiated carcinoma 10.6 SYP ENO2
7 papillary tumor of the pineal region 10.6 SYP ENO2
8 epithelioid neurofibroma 10.6 NF2 NF1
9 bile duct mucinous adenocarcinoma 10.6 SYP ENO2
10 nodular prostate 10.6 SYP ENO2
11 vaginal glandular tumor 10.6 ENO2 CHGA
12 amyloid tumor 10.6 NF2 NF1
13 cloacogenic carcinoma 10.5 SYP ENO2
14 lung meningioma 10.5 SYP NF2
15 primary hepatic neuroendocrine carcinoma 10.5 SYP CHGA
16 retroperitoneal neuroblastoma 10.5 ENO2 CD99
17 pancreas lymphoma 10.5 SYP CHGA
18 cerebellar liponeurocytoma 10.5 SYP ENO2
19 acinar cell cystadenocarcinoma 10.5 SYP CHGA
20 vulvar eccrine porocarcinoma 10.5 SYP CHGA
21 gastrointestinal neuroendocrine benign tumor 10.5 SYP CHGA
22 gastric gastrinoma 10.5 ENO2 CHGA
23 frontal lobe neoplasm 10.5 SYP ENO2
24 mixed ductal-endocrine carcinoma 10.5 SYP CHGA
25 breast papillary carcinoma 10.5 SYP CHGA
26 goblet cell carcinoid 10.5 ENO2 CHGA
27 vaginal tubulovillous adenoma 10.5 SYP CHGA
28 vaginal adenoma 10.5 SYP CHGA
29 hypoganglionosis 10.5 SYP NCAM1
30 lumbosacral plexus lesion 10.5 SYP NF1
31 pineal parenchymal tumor of intermediate differentiation 10.5 SYP ENO2
32 gastric neuroendocrine neoplasm 10.5 SYP CHGA
33 extraskeletal mesenchymal chondrosarcoma 10.5 EWSR1 CD99
34 vaginal benign neoplasm 10.5 SYP CHGA
35 lymphocytic hypophysitis 10.5 POMC ENO2
36 skin granular cell tumor 10.5 NF1 ENO2
37 optic nerve astrocytoma 10.5 SYP NF1 ENO2
38 large cell carcinoma with rhabdoid phenotype 10.5 SMARCB1 ENO2
39 intracranial primitive neuroectodermal tumor 10.5 SYP ENO2 CD99
40 monosomy 22 10.5 SMARCB1 NF2
41 plexiform schwannoma 10.5 NF2 NF1 ENO2
42 liver leiomyosarcoma 10.5 ENO2 CHGA
43 pancreatic gastrinoma 10.5 SYP CHGA
44 polyp of corpus uteri 10.4 NF2 NF1
45 cerebral falx meningioma 10.4 SMARCB1 NF2
46 testicular granulosa cell tumor 10.4 MLANA CD99
47 small cell carcinoma of the bladder 10.4 SYP ENO2 CHGA
48 appendix carcinoid tumor 10.4 SYP ENO2 CHGA
49 auditory system cancer 10.4 SYP ENO2 CHGA
50 thymus small cell carcinoma 10.4 SYP ENO2 CHGA

Graphical network of the top 20 diseases related to Cranial Nerve Neoplasm:



Diseases related to Cranial Nerve Neoplasm

Symptoms & Phenotypes for Cranial Nerve Neoplasm

GenomeRNAi Phenotypes related to Cranial Nerve Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Cranial Nerve Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.7 AVP ENO2 GFAP MYOG NCAM1 NF1
2 nervous system MP:0003631 9.36 AVP CHGA ENO2 GFAP NCAM1 NF1

Drugs & Therapeutics for Cranial Nerve Neoplasm

Search Clinical Trials , NIH Clinical Center for Cranial Nerve Neoplasm

Genetic Tests for Cranial Nerve Neoplasm

Anatomical Context for Cranial Nerve Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Cranial Nerve Neoplasm:

19
Cranial Nerves

MalaCards organs/tissues related to Cranial Nerve Neoplasm:

40
Lung, Prostate, Pineal, Brain, Spinal Cord, Kidney, Breast

Publications for Cranial Nerve Neoplasm

Articles related to Cranial Nerve Neoplasm:

# Title Authors PMID Year
1
Morbid obesity increases risk of morbidity and reoperation in resection of benign cranial nerve neoplasms. 61
27434528 2016
2
Increased Operative Time for Benign Cranial Nerve Tumor Resection Correlates with Increased Morbidity Postoperatively. 61
27441161 2016

Variations for Cranial Nerve Neoplasm

Expression for Cranial Nerve Neoplasm

Search GEO for disease gene expression data for Cranial Nerve Neoplasm.

Pathways for Cranial Nerve Neoplasm

Pathways related to Cranial Nerve Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.76 SYP POMC NF2 NF1 NCAM1 GFAP
2 11.03 SYP NCAM1 GFAP

GO Terms for Cranial Nerve Neoplasm

Cellular components related to Cranial Nerve Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule GO:0030141 8.92 TFF3 POMC CHGA AVP

Sources for Cranial Nerve Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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