MCID: CRN034
MIFTS: 23

Cranial Nerve Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Cranial Nerve Neoplasm

MalaCards integrated aliases for Cranial Nerve Neoplasm:

Name: Cranial Nerve Neoplasm 12 15
Neoplasm of Cranial Nerve 12

Classifications:



External Ids:

Disease Ontology 12 DOID:338
MeSH 43 D003390
NCIt 49 C2963
SNOMED-CT 67 126966009
UMLS 71 C0010267

Summaries for Cranial Nerve Neoplasm

Disease Ontology : 12 A central nervous system cancer develops from schwann cells located in cranial nerves, has material basis in abnormally proliferating cells.

MalaCards based summary : Cranial Nerve Neoplasm, also known as neoplasm of cranial nerve, is related to hydrocephalus and cranial nerve malignant neoplasm. An important gene associated with Cranial Nerve Neoplasm is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Neuroscience and Neural Stem Cells and Lineage-specific Markers. Affiliated tissues include cranial nerves, and related phenotypes are Increased proliferation and nervous system

Related Diseases for Cranial Nerve Neoplasm

Diseases related to Cranial Nerve Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 340)
# Related Disease Score Top Affiliating Genes
1 hydrocephalus 30.1 SYP SMARCB1 GFAP ENO2
2 cranial nerve malignant neoplasm 29.3 SYP POMC OMP NUTM1 NCAM1 MLANA
3 malignant oculomotor nerve tumor 11.4
4 malignant melanocytic neoplasm of the peripheral nerve sheath 10.6 SYP ENO2
5 myocardium cancer 10.6 SYP CD99
6 sinonasal undifferentiated carcinoma 10.6 SYP ENO2
7 papillary tumor of the pineal region 10.6 SYP ENO2
8 pacinian tumor 10.6 NF1 ENO2
9 bile duct mucinous adenocarcinoma 10.6 SYP ENO2
10 epithelioid neurofibroma 10.6 NF2 NF1
11 nodular prostate 10.5 SYP ENO2
12 lung meningioma 10.5 SYP NF2
13 cerebellar liponeurocytoma 10.5 SYP ENO2
14 retroperitoneal neuroblastoma 10.5 ENO2 CD99
15 vaginal glandular tumor 10.5 ENO2 CHGA
16 jejunal neoplasm 10.5 SYP ENO2
17 primary hepatic neuroendocrine carcinoma 10.5 SYP CHGA
18 frontal lobe neoplasm 10.5 SYP ENO2
19 acinar cell cystadenocarcinoma 10.5 SYP CHGA
20 extraskeletal mesenchymal chondrosarcoma 10.5 EWSR1 CD99
21 myoblastoma 10.5 SYP ENO2
22 vulvar eccrine porocarcinoma 10.5 SYP CHGA
23 cervical large cell neuroendocrine carcinoma 10.5 SYP CHGA
24 pineal parenchymal tumor of intermediate differentiation 10.5 SYP ENO2
25 gastrointestinal neuroendocrine benign tumor 10.5 SYP CHGA
26 mixed ductal-endocrine carcinoma 10.5 SYP CHGA
27 goblet cell carcinoid 10.5 ENO2 CHGA
28 gastric gastrinoma 10.5 ENO2 CHGA
29 hypoganglionosis 10.5 SYP NCAM1
30 nodular ganglioneuroblastoma 10.5 ENO2 CHGA
31 vaginal tubulovillous adenoma 10.5 SYP CHGA
32 skin granular cell tumor 10.5 NF1 ENO2
33 meninges hemangiopericytoma 10.5 NF2 CD99
34 breast papillary carcinoma 10.5 SYP CHGA
35 epidural spinal canal neoplasm 10.5 NF2 CD99
36 adrenal neuroblastoma 10.5 SYP ENO2
37 gastric neuroendocrine neoplasm 10.5 SYP CHGA
38 nasal cavity benign neoplasm 10.5 NCAM1 EWSR1
39 lymphocytic hypophysitis 10.5 POMC ENO2
40 appendix lymphoma 10.5 ENO2 CHGA
41 appendix adenocarcinoma 10.5 SYP CHGA
42 cellular neurofibroma 10.5 SMARCB1 NF1
43 pancreatic gastrinoma 10.5 SYP CHGA
44 polyp of corpus uteri 10.5 NF2 NF1
45 ectomesenchymoma 10.5 ENO2 CD99
46 monosomy 22 10.4 SMARCB1 NF2
47 rare tumor 10.4 NF2 EWSR1
48 cellular schwannoma 10.4 NF2 NF1
49 large cell carcinoma with rhabdoid phenotype 10.4 SMARCB1 ENO2
50 plexiform schwannoma 10.4 NF2 NF1 ENO2

Graphical network of the top 20 diseases related to Cranial Nerve Neoplasm:



Diseases related to Cranial Nerve Neoplasm

Symptoms & Phenotypes for Cranial Nerve Neoplasm

GenomeRNAi Phenotypes related to Cranial Nerve Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Cranial Nerve Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.36 AVP CHGA ENO2 GFAP NCAM1 NF1

Drugs & Therapeutics for Cranial Nerve Neoplasm

Search Clinical Trials , NIH Clinical Center for Cranial Nerve Neoplasm

Genetic Tests for Cranial Nerve Neoplasm

Anatomical Context for Cranial Nerve Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Cranial Nerve Neoplasm:

19
Cranial Nerves

Publications for Cranial Nerve Neoplasm

Articles related to Cranial Nerve Neoplasm:

# Title Authors PMID Year
1
Morbid obesity increases risk of morbidity and reoperation in resection of benign cranial nerve neoplasms. 61
27434528 2016
2
Increased Operative Time for Benign Cranial Nerve Tumor Resection Correlates with Increased Morbidity Postoperatively. 61
27441161 2016

Variations for Cranial Nerve Neoplasm

Expression for Cranial Nerve Neoplasm

Search GEO for disease gene expression data for Cranial Nerve Neoplasm.

Pathways for Cranial Nerve Neoplasm

Pathways related to Cranial Nerve Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.76 SYP POMC NF2 NF1 NCAM1 GFAP
2 11.03 SYP NCAM1 GFAP

GO Terms for Cranial Nerve Neoplasm

Cellular components related to Cranial Nerve Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule GO:0030141 8.92 TFF3 POMC CHGA AVP

Sources for Cranial Nerve Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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