MCID: CRN309
MIFTS: 21

Cranial Neuralgia

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Cranial Neuralgia

MalaCards integrated aliases for Cranial Neuralgia:

Name: Cranial Neuralgia 58
Facial Neuralgia 58

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

UMLS via Orphanet 72 C0010269 C0015467
Orphanet 58 ORPHA221109

Summaries for Cranial Neuralgia

MalaCards based summary : Cranial Neuralgia, also known as facial neuralgia, is related to facial neuralgia and migraine with or without aura 1. The drugs Lidocaine and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include cortex and trigeminal ganglion.

Related Diseases for Cranial Neuralgia

Diseases related to Cranial Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 facial neuralgia 11.6
2 migraine with or without aura 1 10.1
3 epidermoid cysts 10.0
4 meningioma, familial 10.0
5 osteonecrosis 10.0
6 pulpitis 10.0
7 spinal meningioma 10.0
8 neuritis 10.0
9 secretory meningioma 10.0
10 lymphoplasmacyte-rich meningioma 10.0
11 central pain syndrome 10.0
12 postherpetic neuralgia 10.0
13 trigeminal neuralgia 9.9
14 glossopharyngeal neuralgia 9.9
15 neuropathy 9.9
16 headache 9.9
17 multiple sclerosis 9.8
18 keratitis, hereditary 9.8
19 brittle bone disorder 9.8
20 ptosis 9.8
21 osteomyelitis 9.8
22 horner's syndrome 9.8
23 dysthymic disorder 9.8
24 acoustic neuroma 9.8
25 mental depression 9.8
26 neuroma 9.8
27 dental caries 9.8
28 myoma 9.8
29 neurotic disorder 9.8
30 periodontitis 9.8
31 herpes simplex 9.8
32 exophthalmos 9.8
33 periostitis 9.8
34 cluster headache 9.8
35 persistent idiopathic facial pain 9.8

Graphical network of the top 20 diseases related to Cranial Neuralgia:



Diseases related to Cranial Neuralgia

Symptoms & Phenotypes for Cranial Neuralgia

Drugs & Therapeutics for Cranial Neuralgia

Drugs for Cranial Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 3 137-58-6 3676
2
Dopamine Approved Phase 3 51-61-6, 62-31-7 681
3
Prochlorperazine Approved, Vet_approved Phase 3 1984-02-6, 58-38-8 4917
4 Neurotransmitter Agents Phase 3
5 Dopamine Agents Phase 3
6 Sodium Channel Blockers Phase 3
7 Anesthetics Phase 3
8 Dopamine Antagonists Phase 3
9 Gastrointestinal Agents Phase 3
10 Diuretics, Potassium Sparing Phase 3
11 Psychotropic Drugs Phase 3
12 Antipsychotic Agents Phase 3
13 Anesthetics, Local Phase 3
14 Anti-Arrhythmia Agents Phase 3
15 Antiemetics Phase 3
16
Guaifenesin Approved, Investigational, Vet_approved Phase 2 93-14-1 3516
17
Dextromethorphan Approved Phase 2 125-71-3 5360696 5362449
18
Topiramate Approved Phase 2 97240-79-4 5284627
19 Respiratory System Agents Phase 2
20 Antitussive Agents Phase 2
21 Chlorpheniramine, phenylpropanolamine drug combination Phase 2
22 Excitatory Amino Acid Antagonists Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Sphenopalatine Ganglion Block for Treating Acute Frontal Migraine Headache in Pediatric Patients Recruiting NCT03984045 Phase 3 Lidocaine topical;Prochlorperazine Injection
2 Clinical Trials in Orofacial Neuralgias Completed NCT00001725 Phase 2 Dextromethorphan
3 A Randomized Clinical Trial of the Effect of Low Level Laser Therapy in Myofacial Pain Syndrome Unknown status NCT01417637
4 Treatment of Chronic Myofascial Pain Syndrome Over Neck by Using Intravascular Laser Irradiation of Blood Unknown status NCT02470000
5 Is Low-level Laser on Traditional Acupoint as Effective as That on Trigger Point in the Management of Cervical Myofascial Pain Syndrome? Completed NCT01516502
6 A Comparative Study of Two Dry Needling Interventions for Plantar Heel Pain: A Randomized Clinical Trial Completed NCT03236779
7 CSF Leak Following Microvascular Decompression: the Benefit of Routine Postoperative Lumbar Tap Withdrawn NCT01932255

Search NIH Clinical Center for Cranial Neuralgia

Genetic Tests for Cranial Neuralgia

Anatomical Context for Cranial Neuralgia

MalaCards organs/tissues related to Cranial Neuralgia:

40
Cortex, Trigeminal Ganglion

Publications for Cranial Neuralgia

Articles related to Cranial Neuralgia:

(show top 50) (show all 316)
# Title Authors PMID Year
1
Frank Hartley and his Contribution to Surgery. 61
33339489 2020
2
Pearls for Interpreting Neurosurgical Systematic Reviews and Meta-Analyses: Lessons From a Collaborative Effort. 61
32140720 2020
3
Bilateral Atypical Facial Pain Caused by Eagle's Syndrome. 61
32181021 2020
4
Clinical assessment, diagnosis and management of patients with unilateral sinonasal disease. 61
31349894 2020
5
Recurrent painful ophthalmoplegic neuropathy: MRI findings in 2 patients. 61
31236187 2019
6
Eslicarbazepine acetate for neuropathic pain, headache, and cranial neuralgia: Evidence and experience. 61
28215909 2019
7
Orofacial neuralgia associated with a middle cerebral artery aneurysm. 61
30525205 2019
8
Trigeminal hypertrophic interstitial neuropathy presenting as unilateral proptosis, ptosis, tearing, and facial neuralgia. 61
30302419 2018
9
Morphological variations of lingula and prevalence of accessory mandibular foramina in mandibles: A study. 61
30546225 2018
10
Botulinum toxin for facial neuralgia. 61
29930362 2018
11
Short-Lasting Unilateral Neuralgiform Headache Attacks. 61
29720816 2018
12
Treatment of Facial Pain with I Ching Balance Acupuncture. 61
29279736 2017
13
Trigeminal Neuralgia: Toward a Multimodal Approach. 61
28377244 2017
14
Other facial neuralgias. 61
28133989 2017
15
Clinical analysis and surgical treatment of trigeminal neuralgia caused by vertebrobasilar dolichoectasia: A retrospective study. 61
28392449 2017
16
Abducent nerve palsy after microballoon compression of the trigeminal ganglion: Case report. 61
28713629 2017
17
Linear headache: clinical characteristics of eight new cases. 61
27057481 2016
18
Cranial Neuralgias. 61
26252592 2015
19
Eagle's syndrome veiling as pain of odontogenic origin: Report of two cases with cone beam computed tomography illustration. 61
27390501 2015
20
Sphenopalatine ganglion electrical nerve stimulation implant for intractable facial pain. 61
26000687 2015
21
Cranial neuralgia vs entrapment neuropathy decompression … better names than migraine trigger site deactivation surgery. 61
25882274 2015
22
Ophthalmic branch radiofrequency thermocoagulation for atypical trigeminal neuralgia:a case report. 61
26722633 2015
23
Microvascular decompression of the posterior inferior cerebellar artery for intermediate nerve neuralgia. 61
25883844 2015
24
Linear headache: a recurrent unilateral head pain circumscribed in a line-shaped area. 61
24966056 2014
25
[Herpes zoster-induced neuralgia (neuropathy)]. 61
25715496 2014
26
Successful Management of Refractory Headache and Facial Pain due to Cavernous Sinus Meningioma with Sphenopalatine Ganglion Radiofrequency. 61
25343051 2014
27
Lacrimal neuralgia: so far, a missing cranial neuralgia. 61
23674831 2013
28
"Ophthalmoplegic migraine: migraine variant or cranial neuralgia?" by PK Chen and SJ Wang. 61
23197352 2013
29
Pain in trigeminal neuralgia: neurophysiology and measurement: a comprehensive review. 61
24701256 2013
30
Ophthalmoplegic migraine: migraine or oculomotor neuropathy? 61
23150890 2012
31
Characteristics of neurovascular compression in facial neuralgia patients by 3D high-resolution MRI and fusion technology. 61
23199722 2012
32
Characterization of neurovascular compression in facial neuralgia patients by 3D high-resolution MRI and image fusion technique. 61
22575982 2012
33
Ophthalmoplegic "migraine" or recurrent ophthalmoplegic cranial neuropathy: new cases and a systematic review. 61
22241707 2012
34
Ophthalmoplegic migraine: migraine variant or cranial neuralgia? 61
22345631 2012
35
Microendoscopic stereotactic-guided percutaneous radiofrequency trigeminal nucleotractotomy. 61
21999320 2012
36
Varicella-zoster virus infection and nummular headache: a possible association with epicranial neuralgia. 61
22975564 2012
37
[Neurotrophic ulceration following thermocoagulation of the Gasserian ganglion]. 61
21958840 2011
38
[Sinonasal headache--reality or mis-diagnosis?]. 61
22046791 2011
39
Virtual reality imaging technique in percutaneous radiofrequency rhizotomy for intractable trigeminal neuralgia. 61
19150598 2009
40
[Headache and facial pain in the elderly]. 61
17926068 2007
41
Idiopathic bilateral trigeminal neuralgia treated by bilateral microvascular decompression. 61
18050077 2007
42
[Atypical neuroleptics in the treatment of atypical facial neuralgia. Two case reports]. 61
17786865 2007
43
MRI findings in pediatric ophthalmoplegic migraine: a case report and literature review. 61
17628225 2007
44
[Classification of headache disorders]. 61
17431685 2007
45
[Naevus of Ota and idiopathic facial neuralgia: association or coincidence?]. 61
17384554 2007
46
Trigeminal neuralgia. 61
16700659 2006
47
[Drug-induced refractory arterial hypertension]. 61
16323733 2005
48
Facial pain in a neurological tertiary care centre--evaluation of the International Classification of Headache Disorders. 61
16109050 2005
49
[Medication, steel or radiation? The appropriate strategy to treat facial neuralgia]. 61
15957859 2005
50
[New international classification of headache disorders (ICHD-II)]. 61
15651338 2004

Variations for Cranial Neuralgia

Expression for Cranial Neuralgia

Search GEO for disease gene expression data for Cranial Neuralgia.

Pathways for Cranial Neuralgia

GO Terms for Cranial Neuralgia

Sources for Cranial Neuralgia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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