MCID: CRS005
MIFTS: 44

Crest Syndrome

Categories: Genetic diseases, Rare diseases, Skin diseases

Aliases & Classifications for Crest Syndrome

MalaCards integrated aliases for Crest Syndrome:

Name: Crest Syndrome 12 74 52 54 43 15 71
Calcinosis-Raynaud Phenomenon-Esophageal Involvement-Sclerodactyly-Telangiectasia Syndrome 52
Calcinosis - Raynaud Phenomenon - Esophageal Involvement - Sclerodactyly - Telangiectasia 52
Systemic Sclerosis, Susceptibility to 52
Scleroderma, Familial Progressive 52

Classifications:



Summaries for Crest Syndrome

NIH Rare Diseases : 52 CREST syndrome , also known as limited scleroderma, is a widespread connective tissue disease characterized by changes in the skin, blood vessels, skeletal muscles, and internal organs . The symptoms involved in CREST syndrome are associated with the generalized form of the disease systemic sclerosis (scleroderma ). CREST is an acronym for the clinical features that are seen in a patient with this disease. (C) - Calcinosis: calcium deposits in the connective tissues (R) - Raynaud's phenomenon: where the hands and feet turn white and cold and then blue, in response to cold or anxiety (E) - Esophageal dysfunction resulting in swallowing difficulty (S) - Sclerodactyly: thick and tight skin on the fingers, caused by an excess of collagen deposits within skin layers. (T) - Telangiectasia: small red spots on the hands and face that are caused by the swelling of tiny blood vessels. At least two of these five features need to be present to be diagnosed with the disease. CREST syndrome is believed to be an autoimmune disorder, where the immune system appears to stimulate the production of too much collagen which builds up in the skin and internal organs, impairing their function. There is no cure. Current treatment focuses on relieving signs and symptoms and preventing complications.

MalaCards based summary : Crest Syndrome, also known as calcinosis-raynaud phenomenon-esophageal involvement-sclerodactyly-telangiectasia syndrome, is related to scleroderma, familial progressive and gastric antral vascular ectasia. An important gene associated with Crest Syndrome is CENPB (Centromere Protein B), and among its related pathways/superpathways are Cell Cycle, Mitotic and Signaling by Rho GTPases. The drugs Ropivacaine and Anesthetics, Local have been mentioned in the context of this disorder. Affiliated tissues include skin, skeletal muscle and bone, and related phenotypes are nausea and vomiting and edema

Disease Ontology : 12 A syndrome characterized by calcinosis, Raynaud's phenomeno, esophageal dysmotility, sclerodactyly and telangiectasia.

Wikipedia : 74 CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem... more...

Related Diseases for Crest Syndrome

Diseases related to Crest Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 208, show less)
# Related Disease Score Top Affiliating Genes
1 scleroderma, familial progressive 33.7 TOP1 CENPB
2 gastric antral vascular ectasia 32.6 TOP1 CENPS
3 limited scleroderma 31.2 TOP1 SNRNP70 EXOSC10 CENPS CENPC CENPB
4 systemic scleroderma 31.0 TOP1 SNRNP70 H2AC18 EXOSC10 CENPB CD40LG
5 diffuse scleroderma 30.0 TOP1 SNRNP70 EXOSC10 CENPB
6 telangiectasis 29.8 TOP1 SNRNP70 H2AC18 EXOSC10 CENPS CENPB
7 primary biliary cirrhosis 29.7 SP100 NUP210 CENPB CD40LG
8 xerophthalmia 29.4 CENPB CD40LG
9 connective tissue disease 28.9 TOP1 SNRNP70 H2AC18 CENPC CENPB CD40LG
10 peripheral nervous system disease 28.8 SOX10 H2AC18 CD40LG
11 dyskinesia of esophagus 28.7 TOP1 SNRNP70 EXOSC10 CENPS CENPC CENPB
12 collagen disease 28.6 TOP1 SNRNP70 H2AC18 EXOSC10 CENPB CD40LG
13 rheumatic disease 28.6 TOP1 H2AC18 CENPB CENPA CD40LG
14 raynaud disease 28.6 TOP1 SNRNP70 CENPB CENPA CD40LG
15 calcinosis 10.6
16 raynaud phenomenon 10.5
17 pulmonary hypertension 10.4
18 heart block, congenital 10.3 SNRNP70 H2AC18
19 liver cirrhosis 10.3
20 spinocerebellar ataxia type 1 with axonal neuropathy 10.3 TOP1 H2AC18
21 facial hemiatrophy 10.2 SNRNP70 EXOSC10
22 syndromic x-linked intellectual disability cabezas type 10.2 TOP1 EXOSC10
23 autoimmune disease 10.1
24 vascular disease 10.1
25 idiopathic interstitial pneumonia 10.1
26 pulmonary fibrosis 10.1
27 vasculitis 10.1
28 uveitis 10.0
29 nodular regenerative hyperplasia 10.0
30 sjogren syndrome 10.0
31 interstitial lung disease 10.0
32 mixed connective tissue disease 10.0
33 dysphagia 10.0
34 cataract 31, multiple types 9.9 AGBL3 AGBL2
35 pulmonary hypertension, primary, 1 9.9
36 branchiootic syndrome 1 9.9
37 reynolds syndrome 9.9
38 keratoconjunctivitis sicca 9.9
39 thyroiditis 9.9
40 lung disease 9.9
41 western equine encephalitis 9.9 H2AC18 CD40LG
42 orchitis 9.9 H2AC18 CD40LG
43 schuurs-hoeijmakers syndrome 9.8 H2AC18 CD40LG
44 hirschsprung disease 1 9.8
45 migraine with or without aura 1 9.8
46 sarcoidosis 1 9.8
47 varicose veins 9.8
48 pulmonary venoocclusive disease 2, autosomal recessive 9.8
49 pulmonary venoocclusive disease 1, autosomal dominant 9.8
50 waardenburg syndrome, type 4a 9.8
51 deficiency anemia 9.8
52 hepatic veno-occlusive disease 9.8
53 dermatomyositis 9.8
54 respiratory failure 9.8
55 pulmonary edema 9.8
56 hemopericardium 9.8
57 pericardial effusion 9.8
58 panuveitis 9.8
59 hereditary hemorrhagic telangiectasia 9.8
60 branch retinal artery occlusion 9.8
61 polyneuropathy 9.8
62 ectropion 9.8
63 thrombocytopenia 9.8
64 pericarditis 9.8
65 autoimmune hepatitis 9.8
66 gastritis 9.8
67 pulmonary venoocclusive disease 9.8
68 retinal artery occlusion 9.8
69 keratoconjunctivitis 9.8
70 iridocyclitis 9.8
71 cutaneous sclerosis 9.8
72 splenomegaly 9.8
73 aneurysm 9.8
74 cerebral aneurysms 9.8
75 immunodeficiency with hyper-igm, type 2 9.8 H2AC18 CD40LG
76 cecal disease 9.8 H2AC18 CD40LG
77 immune-complex glomerulonephritis 9.7 H2AC18 CD40LG
78 acroosteolysis 9.7
79 amyloidosis, primary localized cutaneous, 1 9.7
80 spondyloarthropathy 1 9.7
81 biliary cirrhosis, primary, 1 9.7
82 coloboma of macula 9.7
83 hypertelorism 9.7
84 lichen sclerosus et atrophicus 9.7
85 piebald trait 9.7
86 porphyria cutanea tarda 9.7
87 dowling-degos disease 1 9.7
88 temporal arteritis 9.7
89 anemia, autoimmune hemolytic 9.7
90 conotruncal heart malformations 9.7
91 moyamoya disease 1 9.7
92 myasthenia gravis 9.7
93 myelofibrosis 9.7
94 abnormal hair, joint laxity, and developmental delay 9.7
95 ataxia and polyneuropathy, adult-onset 9.7
96 abcd syndrome 9.7
97 phace association 9.7
98 patent ductus arteriosus 1 9.7
99 granulomatosis with polyangiitis 9.7
100 peripheral demyelinating neuropathy, central dysmyelination, waardenburg syndrome, and hirschsprung disease 9.7
101 intraocular pressure quantitative trait locus 9.7
102 cyanosis, transient neonatal 9.7
103 muscle hypertrophy 9.7
104 myelodysplastic syndrome 9.7
105 graft-versus-host disease 9.7
106 hydrops, lactic acidosis, and sideroblastic anemia 9.7
107 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.7
108 tendinosis 9.7
109 aspiration pneumonia 9.7
110 familial adenomatous polyposis 9.7
111 primary cutaneous amyloidosis 9.7
112 renal fibrosis 9.7
113 lymphoma 9.7
114 ptosis 9.7
115 migraine with aura 9.7
116 osteonecrosis 9.7
117 chronic endophthalmitis 9.7
118 portal hypertension 9.7
119 intracranial aneurysm 9.7
120 esophageal varix 9.7
121 megacolon 9.7
122 constrictive pericarditis 9.7
123 cardiac tamponade 9.7
124 mitral valve insufficiency 9.7
125 retinal vasculitis 9.7
126 esophagitis 9.7
127 cryptococcosis 9.7
128 inflammatory spondylopathy 9.7
129 central retinal artery occlusion 9.7
130 porphyria 9.7
131 scleritis 9.7
132 patent foramen ovale 9.7
133 sick sinus syndrome 9.7
134 peptic esophagitis 9.7
135 mononeuritis multiplex 9.7
136 cholecystitis 9.7
137 constipation 9.7
138 hepatitis 9.7
139 protein s deficiency 9.7
140 larynx cancer 9.7
141 chondroma 9.7
142 glomerulonephritis 9.7
143 periarthritis 9.7
144 adenocarcinoma 9.7
145 myelitis 9.7
146 lipid pneumonia 9.7
147 ischemia 9.7
148 plexopathy 9.7
149 extraskeletal chondroma 9.7
150 intestinal pseudo-obstruction 9.7
151 tricuspid valve insufficiency 9.7
152 hyperglycemia 9.7
153 hypertrichosis 9.7
154 macular retinal edema 9.7
155 endophthalmitis 9.7
156 rapidly progressive glomerulonephritis 9.7
157 pancreatitis 9.7
158 eye disease 9.7
159 hemolytic anemia 9.7
160 esophageal disease 9.7
161 reactive arthritis 9.7
162 spondylitis 9.7
163 juvenile rheumatoid arthritis 9.7
164 peptic ulcer disease 9.7
165 cataract 9.7
166 ileus 9.7
167 localized scleroderma 9.7
168 neuropathy 9.7
169 dermatophytosis 9.7
170 amyloidosis 9.7
171 hard palate cancer 9.7
172 achalasia 9.7
173 lichen planus 9.7
174 waardenburg's syndrome 9.7
175 exophthalmos 9.7
176 hypopituitarism 9.7
177 cholangitis 9.7
178 bronchiectasis 9.7
179 albinism 9.7
180 47,xyy 9.7
181 banti's syndrome 9.7
182 chronic graft versus host disease 9.7
183 chronic intestinal pseudoobstruction 9.7
184 encephalocele 9.7
185 hemiplegic migraine 9.7
186 hypoganglionosis 9.7
187 linear scleroderma 9.7
188 localized lipodystrophy 9.7
189 polymyositis 9.7
190 spondylarthropathy 9.7
191 sporadic hemiplegic migraine 9.7
192 back pain 9.7
193 chronic pain 9.7
194 headache 9.7
195 hypotonia 9.7
196 tremor 9.7
197 nodular cutaneous amyloidosis 9.7
198 congenital ectropion uveae 9.7
199 refractory anemia 9.7
200 congenital ectropion 9.7
201 tenosynovitis 9.6 CD40LG AGBL2
202 streptococcus pneumonia 9.6 H2AC18 CD40LG
203 cholangitis, primary sclerosing 9.6 SP100 NUP210 CD40LG
204 childhood type dermatomyositis 9.6 SNRNP70 EXOSC10 CD40LG
205 autoimmune disease of musculoskeletal system 9.5 TOP1 SNRNP70 H2AC18 CD40LG
206 autoimmune disease of urogenital tract 9.5 SP100 NUP210 H2AC18 CD40LG
207 goodpasture syndrome 9.5 H2AC18 CD40LG
208 muscular disease 9.3 SNRNP70 H2AC18 EXOSC10 CD40LG

Graphical network of the top 20 diseases related to Crest Syndrome:



Diseases related to Crest Syndrome

Symptoms & Phenotypes for Crest Syndrome

Human phenotypes related to Crest Syndrome:

31 (showing 16, show less)
# Description HPO Frequency HPO Source Accession
1 nausea and vomiting 31 hallmark (90%) HP:0002017
2 edema 31 hallmark (90%) HP:0000969
3 lack of skin elasticity 31 hallmark (90%) HP:0100679
4 autoimmunity 31 hallmark (90%) HP:0002960
5 stiff skin 31 hallmark (90%) HP:0030053
6 epigastric auras 31 hallmark (90%) HP:0011159
7 sclerodactyly 31 hallmark (90%) HP:0011838
8 abnormal fingertip morphology 31 hallmark (90%) HP:0001211
9 calcinosis 31 hallmark (90%) HP:0003761
10 dysphagia 31 frequent (33%) HP:0002015
11 dyspnea 31 frequent (33%) HP:0002094
12 telangiectasia of the skin 31 frequent (33%) HP:0100585
13 skin ulcer 31 frequent (33%) HP:0200042
14 lip telangiectasia 31 frequent (33%) HP:0000214
15 pulmonary fibrosis 31 occasional (7.5%) HP:0002206
16 pulmonary arterial hypertension 31 occasional (7.5%) HP:0002092

Drugs & Therapeutics for Crest Syndrome

Drugs for Crest Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 24, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
2 Anesthetics, Local Phase 4
3 Anesthetics Phase 4
4 Central Nervous System Depressants Phase 4
5
Bupivacaine Approved, Investigational Phase 2, Phase 3 38396-39-3, 2180-92-9 2474
6
Epinephrine Approved, Vet_approved 51-43-4 5816
7
Racepinephrine Approved 329-65-7 838
8
Nitric Oxide Approved 10102-43-9 145068
9
Calcium Approved, Nutraceutical 7440-70-2 271
10 Hormones
11 Calcium, Dietary
12 Epinephryl borate
13 Pharmaceutical Solutions
14 Analgesics, Opioid
15 Analgesics
16 Neurotransmitter Agents
17 Respiratory System Agents
18 Anti-Asthmatic Agents
19 Autonomic Agents
20 Free Radical Scavengers
21 Vasodilator Agents
22 Antioxidants
23 Protective Agents
24 Bronchodilator Agents

Interventional clinical trials:

(showing 7, show less)
# Name Status NCT ID Phase Drugs
1 Intérêt du TFP (Transversalis Fascia Plane) Bloc échoguidé Pour l'analgésie du prélèvement Osseux de crête Iliaque Completed NCT02398474 Phase 4 TFP block ropivacaine;ropivacaine infiltration of the iliac crest bone
2 Chemical Sympathectomy Following Peripheral Nerve Block With Liposomal Bupivacaine Terminated NCT02374320 Phase 2, Phase 3 liposomal bupivacaine
3 Phase I Trial of High Dose Rate Brachytherapy Combined With Stereotactic Body Radiation Therapy for Intermediate Risk Prostate Cancer Patients Active, not recruiting NCT01655836 Phase 1
4 Comparative Clinical Study of the Prevention of the Reduction of Alveolar Crest by Alveoli Filling With an Injectable Calcium Phosphate After Extraction of Mandibular Molar or Pre Molar Unknown status NCT00740311
5 The Analgesic Efficacy of the Transversalis Fascia Plane Block in Iliac Crest Bone Graft Harvesting Completed NCT01133730 Active treatment;Placebo Arm
6 A Prospective Pilot Study on the Performance of The Plexur P™ Bone Void Filler Completed NCT00837473
7 Localized Effects of Photobiomodulation and Exogenous Nitric Oxide on CREST Patients Calcinosis Cutis & Raynaud Phenomenon Not yet recruiting NCT03972566 INOMAX

Search NIH Clinical Center for Crest Syndrome

Cochrane evidence based reviews: crest syndrome

Genetic Tests for Crest Syndrome

Anatomical Context for Crest Syndrome

MalaCards organs/tissues related to Crest Syndrome:

40
Skin, Skeletal Muscle, Bone, Lung, Liver, Testes, Heart

Publications for Crest Syndrome

Articles related to Crest Syndrome:

(showing 508, show less)
# Title Authors PMID Year
1
Eukaryotic expression of recombinant human centromere autoantigen and its use in a novel ELISA for diagnosis of CREST syndrome. 54 61
8198697 1994
2
Successful treatment of calcinosis cutis of fingertip in the setting of CREST syndrome with topical 20% sodium thiosulfate. 61
31709293 2019
3
Distal Phalanx Osteolysis and Subcutaneous Calcinosis in CREST Syndrome. 61
31764379 2019
4
Autoimmune associations in a Mexican cohort with primary biliary cholangitis. 61
30017344 2019
5
Chronic Anterior Uveitis in a Patient with CREST Syndrome. 61
30691950 2019
6
Botulinum toxin for treatment of Raynaud phenomenon in CREST syndrome. 61
30677800 2018
7
A Rare Cause of Leg Ulcer: Calcinosis Cutis as a Part of CREST Syndrome. 61
30270692 2018
8
Imaging studies of kleptomania in a middle-aged woman with obsessive-compulsive disorder: a case report. 61
29987861 2018
9
Dermoscopic patterns of filiform papillae of the tongue in patients with and without connective tissue autoimmune diseases. 61
29774953 2018
10
Retinal vasculitis associated with CREST syndrome. 61
29780934 2018
11
Orbital Inflammation as a Presenting Sign for CREST Syndrome. 61
28990976 2018
12
Refractory Hepatic Hydrothorax: A Rare Complication of Systemic Sclerosis and Presinusoidal Portal Hypertension. 61
29854501 2018
13
Cardio-cephalic neural crest syndrome: A novel hypothesis of vascular neurocristopathy. 61
28814167 2017
14
Cutaneous calcinosis in a patient with limited scleroderma: CREST Syndrome. 61
29308290 2017
15
Cutaneous metastasis to the scalp as the primary presentation of colorectal adenocarcinoma. 61
29447644 2017
16
Upper gastrointestinal bleeding (watermelon stomach) in a patient with limited scleroderma (CREST syndrome). 61
27353193 2017
17
Pulmonary Capillary Hemangiomatosis Associated with CREST Syndrome: A Challenge of Diagnosis and Treatment. 61
29067967 2017
18
Coexistent Primary Biliary Cholangitis with CREST Syndrome (Reynolds Syndrome). 61
28602872 2017
19
Esophagocardioplasty, vagotomy-antrectomy and Roux-en-Y gastrojejunostomy: indication in cases with severe esophageal motor disfunction. 61
29040484 2017
20
CREST Syndrome: Clinical Expression of the Disease. 61
28742726 2017
21
Intravenous sodium thiosulfate for treating tumoral calcinosis associated with systemic disorders: Report of four cases. 61
27955821 2017
22
CREST Calcinosis Affecting the Lumbar and Cervical Spine and the Use of Minimally-Invasive Surgery. 61
28491486 2017
23
Complications in Placement of a Glaucoma Drainage Device in a Patient With CREST Syndrome. 61
27811572 2017
24
Evidence for the Use of Epoprostenol to Treat Raynaud's Phenomenon With or Without Digital Ulcers. 61
27465880 2016
25
Worsening of calcinosis cutis with teriparatide treatment in two osteoporotic patients. 61
26992073 2016
26
The Risk of Vocal Fold Atrophy after Serial Corticosteroid Injections of the Vocal Fold. 61
26620260 2016
27
Comparison of Screening Dilution and Automated Reading for Antinuclear Antibody Detection on HEP2 Cells in the Monitoring of Connective Tissue Diseases. 61
27225012 2016
28
Different contributions of angiostatin and endostatin in angiogenesis impairment in systemic sclerosis: a cohort study. 61
26885625 2016
29
Reversed shunting in CREST syndrome. 61
26678219 2016
30
Assessment and Surgical Treatment of Calcinosis of the Shoulder Associated with CREST Syndrome. 61
27437158 2016
31
A case of a generalized symptomatic calcinosis in systemic sclerosis. 61
27833984 2016
32
Crest Syndrome. 61
27072730 2016
33
Autoimmune liver disease and concomitant extrahepatic autoimmune disease. 61
26148248 2015
34
Osteonecrosis of multiple joints in a patient with limited scleroderma/CREST syndrome. 61
25807102 2015
35
Tinea Incognita in a Patient with Crest Syndrome: Case Report. 61
26476904 2015
36
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity. 61
26513367 2015
37
Dehydrated Amniotic Membrane Allograft for Treatment of Chronic Leg Ulcers in Patients With Multiple Comorbidities: A Case Series. 61
27104144 2014
38
Cryoglobulinemic vasculitis in a patient with CREST syndrome. 61
24852904 2014
39
A case of acute autoimmune hepatitis presenting after incomplete-type CREST syndrome and chronic thyroiditis. 61
25195969 2014
40
Oral medicine case book 62: CREST syndrome. 61
26548213 2014
41
Pathophysiology and recent findings of primary biliary cirrhosis complicated by systemic sclerosis. 61
24308674 2014
42
Dystrophic calcifications and Raynaud's phenomenon in an eight-year old girl. 61
24839783 2014
43
Pulsed versus continuous wave low-level light therapy on osteoarticular signs and symptoms in limited scleroderma (CREST syndrome): a case report. 61
25393970 2014
44
Telangiectasis in CREST syndrome and systemic sclerosis: correlation of clinical and pathological features with response to pulsed dye laser treatment. 61
23494102 2014
45
[The road to early diagnosis of systemic sclerosis : the evolution of diagnostic and classification criteria in the past decades]. 61
24337197 2013
46
Clinical significance of autoantibodies to the pericentromeric heterochromatin protein 1a protein. 61
24184038 2013
47
Surgical management of digital calcinosis in CREST syndrome. 61
24142114 2013
48
Surgical treatment of extensive subcutaneous calcification of the forearm in CREST syndrome. 61
23849984 2013
49
[Hyperostosis frontalis interna and epilepsy]. 61
24303658 2013
50
Scleroderma and IgG4-related disease. 61
23563250 2013
51
Incidence of scleroderma spectrum disorders in Slovenia. 61
23190708 2013
52
HCV-related autoimmune disorders in HCV chronic infection. 61
24045529 2013
53
Successful management of an inadvertent excessive treprostinil overdose. 61
23662045 2013
54
Primary cutaneous cryptococcosis in a patient with CREST syndrome. 61
22381693 2012
55
Peripheral phenomena in a woman with calcinosis, raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia (CREST) syndrome-associated pulmonary hypertension. 61
22392867 2012
56
CREST syndrome with pulmonary arterial hypertension. 61
22333384 2012
57
Anti-myelin-associated glycoprotein polyneuropathy coexistent with CREST syndrome. 61
22387650 2012
58
Slowly progressive insulin-dependent diabetes in a patient with primary biliary cirrhosis with portal hypertension-type progression. 61
22214628 2012
59
Partial breast irradiation in a patient with bilateral breast cancers and CREST syndrome. 61
21349774 2011
60
Non-healing leg ulcers in a patient with dystrophic calcification and crest syndrome: a challenging clinical case. 61
21827631 2011
61
Scleroderma and CREST syndrome: a case report in dentistry. 61
21956352 2011
62
Coronary artery abnormalities in CREST syndrome revealed by cardiovascular magnetic resonance imaging. 61
21474271 2011
63
Diagnosis and classification of systemic sclerosis. 61
20143182 2011
64
Livedo reticularis and bowel ischemia after carbon dioxide arteriography in a patient with CREST syndrome. 61
21277800 2011
65
Historical perspectives on the discovery and elucidation of autoantibodies to centromere proteins (CENP) and the emerging importance of antibodies to CENP-F. 61
20933614 2011
66
Small lymphocytic lymphoma in a patient with CREST syndrome. 61
21982887 2011
67
[Cor pulmonale-PHT secondary to crest syndrome. Treatment with slow continuous ultrafiltration]. 61
20346544 2010
68
Gastric variceal bleeding uncovering a rare association of CREST syndrome, primary biliary cirrhosis, nodular regenerative hyperplasia and pulmonary hypertension. 61
20485183 2010
69
Multiple cerebral aneurysms in a patient with CREST syndrome. 61
20510616 2010
70
Orbital bone and soft tissue calcification in CREST syndrome. 61
20584022 2010
71
Lung atelectasis secondary to massive esophageal dilation in a patient with scleroderma. 61
20808981 2010
72
Calcinosis cutis and Sjögren's syndrome. 61
20156928 2010
73
[Dystrophic calcinosis of the vulva in a patient with CREST syndrome]. 61
20734547 2010
74
Sporadic hemiplegic migraine and CREST syndrome. 61
20130953 2010
75
Elevated adiponectin serum levels in women with systemic autoimmune diseases. 61
21234350 2010
76
Intraoral telangiectasias associated with Raynaud disease: a report of two cases. 61
19907728 2010
77
Taxane-induced morphea in a patient with CREST syndrome. 61
25386245 2010
78
Pulmonary capillary hemangiomatosis associated with CREST syndrome: a case report and review of the literature. 61
20453487 2010
79
Peripheral arterial thrombosis with presence of anti-centromere antibodies and polycythemia vera. 61
19902720 2009
80
Intracranial aneurysms in patients with CREST syndrome. 61
19779284 2009
81
Association of collagenous colitis with prurigo nodularis. 61
19398916 2009
82
[Calcinosis. Limited systemic sclerosis (CREST syndrome)]. 61
19371916 2009
83
[Autoantibodies in systemic sclerosis: clinical interest and diagnosis approach]. 61
19411229 2009
84
[A 64-year-old woman with perianal bleeding, chronic diarrhea and severe fecal incontinence]. 61
19358063 2009
85
Surgical result of critical limb ischemia due to tibial arterial occlusion in patients with systemic scleroderma. 61
19223137 2009
86
Surgical debridement of painful fingertip calcinosis cutis in CREST syndrome. 61
19221282 2009
87
[A case of anti-AQP4 antibody-positive recurrent myelitis overlapped with autoimmune disorders including incomplete CREST syndrome revealed multiple discontinuous cord lesions]. 61
19348177 2009
88
Acute central retinal artery occlusion presenting as CREST syndrome: a case report. 61
19123948 2009
89
Adenocarcinoma of the third portion of the duodenum in a man with CREST syndrome. 61
18828905 2008
90
Inflammatory morphea in the context of Raynaud phenomenon. 61
19061610 2008
91
Primary localized cutaneous nodular amyloidosis and CREST syndrome: a case report and review of the literature. 61
18712025 2008
92
Juxtafoveolar telangiectasis associated with CREST syndrome. 61
18716957 2008
93
Bilateral infusion pump implants as therapy for refractory corneal ulcers in a patient with CREST syndrome: an interdisciplinary approach. 61
18625944 2008
94
Diagnosis and treatment of scleroderma. 61
18560030 2008
95
Primary biliary cirrhosis. 61
18215315 2008
96
Unusual dyspnea in a woman with CREST syndrome. 61
18187755 2008
97
[Autoimmune hepatitis and CREST syndrome]. 61
18265812 2007
98
Small mouths ... Big problems? A review of scleroderma and its oral health implications. 61
18028759 2007
99
Anti-chromatin and anti-C1q antibodies in systemic lupus erythematosus compared to other systemic autoimmune diseases. 61
17763207 2007
100
Mutations of activin-receptor-like kinase 1 (ALK-1) are not found in patients with pulmonary hypertension and underlying connective tissue disease. 61
16941203 2007
101
Combination therapy with oral sildenafil and beraprost for pulmonary arterial hypertension associated with CREST syndrome. 61
17592207 2007
102
Local implantation of autologous mononuclear cells from bone marrow and peripheral blood for treatment of ischaemic digits in patients with connective tissue diseases. 61
17309890 2007
103
[Low prevalence of anti-centromere antibodies in scleroderma in Morocco (about 272 cases)]. 61
17502303 2007
104
Primary biliary cirrhosis (PBC)-CREST overlap syndrome with coexistence of Sjögren's syndrome and thyroid dysfunction. 61
16496080 2007
105
[Pulmonary arterial hypertension--experience of Centro Hospitalar de Vila Nova de Gaia]. 61
17492235 2007
106
Increased prevalence of anti-third generation cyclic citrullinated peptide antibodies in patients with rheumatoid arthritis and CREST syndrome. 61
17426360 2007
107
Facial anomalies in a patient with cytochrome-oxidase deficiency and subsequent Kearns-Sayre syndrome with growth hormone deficiency. 61
17372585 2007
108
Two cases of primary biliary cirrhosis complicated by acute leukemia. 61
17473489 2007
109
Abnormal pulmonary vascular responses in patients registered with a systemic autoimmunity database: Pulmonary Hypertension Assessment and Screening Evaluation using stress echocardiography (PHASE-I). 61
16431161 2006
110
Enhanced MR imaging of tenosynovitis of hand and wrist in inflammatory arthritis. 61
16941192 2006
111
Soft-tissue infection and underlying calcinosis of CREST syndrome. 61
17060652 2006
112
Congenital iris ectropion and glaucoma associated with intestinal neuronal dysplasia: a manifestation of a neural crest syndrome. 61
17030723 2006
113
Anti-centromere antibodies in patients with systemic lupus erythematosus. 61
16882593 2006
114
Incidence and clinical correlation of anticentromere antibody in Thai patients. 61
16220222 2006
115
Solitary extramedullary plasmacytoma and granulomatous sialadenitis of the parotid gland preceding a B-cell non-Hodgkin's lymphoma. 61
16489463 2006
116
The presence of dominant T-cell clones in peripheral blood of patients with collagen vascular disorders: a prospective study of 97 cases. 61
16445773 2006
117
Intracellular Th1/Th2 balance of pulmonary CD4(+) T cells in patients with active interstitial pneumonia evaluated by serum KL-6. 61
16873097 2006
118
Antimitochondrial antibody negative primary biliary cirrhosis in Japan: utilization of clinical data when patients applied to receive public financial aid. 61
16369106 2006
119
Tumoral calcinosis in the cervical spine in a patient with CREST syndrome. A case report. 61
16391265 2006
120
Treatment of cutaneous calcinosis in CREST syndrome by extracorporeal shock wave lithotripsy. 61
16227105 2005
121
[Risedronate: a possible treatment for extraosseous calcification]. 61
16272635 2005
122
Clinical and serological heterogeneity in patients with anticentromere antibodies. 61
16078324 2005
123
Effect of granulocyte macrophage-colony stimulating factor on extracellular matrix deposition by dermal fibroblasts from patients with scleroderma. 61
15801021 2005
124
Unilateral recurrent laryngeal nerve neuropraxia following placement of a ProSeal laryngeal mask airway in a patient with CREST syndrome. 61
15777310 2005
125
Videodermatoscopy: a useful tool for diagnosing cutaneous dystrophic calcifications. 61
15748569 2005
126
Bone marrow necrosis successfully treated with corticosteroid. 61
15613112 2005
127
Association of an irregularly shaped anterior choroidal aneurysm with CREST syndrome. Case report. 61
15540926 2004
128
[Granulomatous uveitis and CREST syndrome: a case study]. 61
15547474 2004
129
[CREST syndrome and pulmonary hypertension: a dark prognosis]. 61
16197851 2004
130
Successful long-term treatment with cyclosporin A in protein losing gastroenteropathy. 61
15206552 2004
131
Cranial nerve VIII involvement in a patient with progressive systemic sclerosis. 61
15054944 2004
132
Primary biliary cirrhosis and CREST syndrome. 61
15053737 2004
133
[Pulmonary hypertension in patients with systemic scleroderma with CREST-syndrome and without it]. 61
15230125 2004
134
[Pulmonary veno-occlusive disease in a patient with scleroderma and the CREST syndrome]. 61
14713977 2003
135
Physical signs for the general dental practitioner. Case 10. CREST syndrome. 61
14710572 2003
136
Multifocal varicella-zoster virus vasculopathy without rash. 61
14623735 2003
137
[Acrocyanosis: crucial symptom in a case of chronic diarrhea and weight loss]. 61
14689078 2003
138
Severe Raynaud's phenomenon with yohimbine therapy for erectile dysfunction. 61
14677199 2003
139
Primary biliary cirrhosis--presentation and diagnosis. 61
14594129 2003
140
Induction of kinetochore-positive and kinetochore-negative micronuclei in CHO cells by ELF magnetic fields and/or X-rays. 61
12960412 2003
141
Successful palliation and significant remission of cutaneous calcinosis in CREST syndrome with carbon dioxide laser. 61
12930342 2003
142
Anemia in CREST syndrome. 61
12841022 2003
143
[Pulmonary artery hypertension associated with connective tissue diseases]. 61
12856325 2003
144
Annular, semicircular lipoatrophy of the thighs associated with incomplete "CREST" syndrome: Raynaud's, telangiectasias, and esophageal dysmotility. 61
17041445 2003
145
Antibodies to centromere antigens measured by an automated enzyme immunoassay. 61
12559609 2003
146
Prostacyclin for pulmonary hypertension. 61
12804447 2003
147
Isolated trochlear nerve palsy in CREST syndrome. 61
14530626 2003
148
[Anti-neutrophil cytoplasmic autoantibody-associated rapid progressive glomerulonephritis complicated with both limited and diffuse scleroderma]. 61
12599516 2002
149
Pulmonary hypertension associated with connective tissue disease. 61
12525998 2002
150
Amplification of the pulmonary vasodilatory response to inhaled iloprost by subthreshold phosphodiesterase types 3 and 4 inhibition in severe pulmonary hypertension. 61
12441759 2002
151
Bronchiectasis in a patient with CREST syndrome. 61
12477240 2002
152
Primary biliary cirrhosis accompanied by CREST syndrome. 61
12356109 2002
153
[Pulmonary hypertension associated with systemic sclerosis]. 61
12218891 2002
154
Post-menopause is the main risk factor for developing isolated pulmonary hypertension in systemic sclerosis. 61
12114278 2002
155
[CREST syndrome]. 61
12218901 2002
156
Clinicolaboratory characteristics of patients with primary biliary cirrhosis associated with CREST symptoms. 61
11882415 2002
157
Pulmonary edema caused by inhaled nitric oxide therapy in two patients with pulmonary hypertension associated with the CREST syndrome. 61
11834688 2002
158
Scleroderma--CREST syndrome. 61
11867856 2002
159
Protease nexin-1 messenger RNA levels are not affected by serum or interferon beta in cultured systemic sclerosis fibroblasts. 61
11876527 2002
160
Enhanced expression of the receptor for granulocyte macrophage colony stimulating factor on dermal fibroblasts from scleroderma patients. 61
11824978 2002
161
[Pulmonary hypertension associated with connective tissue diseases]. 61
11859694 2002
162
Prostacyclin for pulmonary hypertension. 61
12137667 2002
163
PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation. 61
11762945 2001
164
Three cases of digital ischemia successfully treated with cilostazol. 61
11958391 2001
165
Aerosolized iloprost in CREST syndrome related pulmonary hypertension. 61
11669165 2001
166
Progressive interstitial renal fibrosis due to Chinese herbs in a patient with calcinosis Raynaud esophageal sclerodactyly telangiectasia (CREST) syndrome. 61
11688835 2001
167
The diagnostic quandary of hereditary haemorrhagic telangiectasia vs. CREST syndrome. 61
11703295 2001
168
[Pulmonary hypertension screening in systemic scleroderma: a cohort study of 67 patients]. 61
11599184 2001
169
Disproportionately severe calcinosis cutis in an 88-year-old patient with CREST syndrome. 61
11479756 2001
170
[Elderly-onset anticentromere antibody-positive pulmonary-renal syndrome: report of an autopsy case]. 61
11579530 2001
171
Diltiazem in the treatment of calcinosis in juvenile dermatomyositis. 61
19078635 2001
172
[Oral administration of beraprost sodium did not exacerbate pulmonary hypertension with CREST syndrome]. 61
11460359 2001
173
[Advances in immunoserology tests in clinical medicine: autoantibodies, immune complexes and DNA analysis]. 61
11307318 2001
174
A case of porphyria cutanea tarda in association with idiopathic myelofibrosis and CREST syndrome. 61
11167703 2001
175
Cerebral vasculopathy showing moyamoya-like changes in a patient with CREST syndrome. 61
11598340 2001
176
Fabry's Disease Mimicking an Undifferentiated Connective Tissue Disease. 61
19078496 2000
177
Pulmonary hypertension with limited cutaneous scleroderma (CREST syndrome). 61
11099792 2000
178
Immunohistochemical expression of transforming growth factor beta3 in calcinosis in a patient with systemic sclerosis and CREST syndrome. 61
11069531 2000
179
Fetal microchimerism in primary biliary cirrhosis. 61
11097475 2000
180
Peripheral neuropathy with hypomyelination, chronic intestinal pseudo-obstruction and deafness: a developmental "neural crest syndrome" related to a SOX10 mutation. 61
11026454 2000
181
Limited cutaneous systemic sclerosis associated with MPO-ANCA positive renal small vessel vasculitis of the microscopic polyangiitis type. 61
10977809 2000
182
Granulomatous anterior uveitis in a patient with CREST syndrome. 61
11120581 2000
183
[Severe isolated pulmonary hypertension as main manifestation of Crest syndrome]. 61
10981335 2000
184
[Clinical, serological and genetic study in patients with CREST syndrome] [In Process Citation] 61
10934759 2000
185
Centromeric structure identification in Entamoeba histolytica by anticentromeric/kinetochore antibodies obtained from patients with the CREST syndrome. 61
11070286 2000
186
[CREST syndrome; a changing clinical significance] 61
10934751 2000
187
CREST syndrome; a changing clinical significance. 61
10852154 2000
188
Clinical, serological and genetic study in patients with CREST syndrome. 61
10852162 2000
189
Kinetics of anti-fibrillin-1 autoantibodies in MCTD and CREST syndrome. 61
10756089 2000
190
Granulomatous uveitis, CREST syndrome, and primary biliary cirrhosis. 61
10847709 2000
191
A case of CREST syndrome and myeloperoxidase-specific anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis. 61
10809419 2000
192
A 69-year-Old woman with CREST syndrome, dyspnea, and a mosaic CT attenuation pattern. 61
10669707 2000
193
[Primary biliary cirrhosis and CREST syndrome: a rare classical combination (literature review and case report)]. 61
10717934 2000
194
Myasthenia gravis associated with limited scleroderma (CREST syndrome) 61
10701901 2000
195
[Influence of age on the clinical and biological characteristics of systemic scleroderma]. 61
10635070 1999
196
Motor activity of the gallbladder in systemic sclerosis. 61
10606308 1999
197
[Pre-capillary pulmonary hypertension complicating CREST syndrome. Apropos of a case]. 61
10665332 1999
198
Concomitant spondylarthropathy and CREST syndrome. 61
10609082 1999
199
Scleroderma: what the general dentist should know. 61
10687451 1999
200
Periodontal manifestations of collagen vascular disorders. 61
10551177 1999
201
Late-onset unilateral primary developmental glaucoma associated with iridotrabecular dysgenesis, congenital ectropion uveae and thickened corneal nerves: a new neural crest syndrome? 61
10929982 1999
202
Dysgenesis of the internal carotid artery associated with transsphenoidal encephalocele: a neural crest syndrome? 61
10445462 1999
203
Phlebosclerosis of the colon with positive anti-centromere antibody. 61
10397079 1999
204
CREST syndrome and periodontal surgery: a case report. 61
10368058 1999
205
Peritoneal dialysis-associated peritonitis caused by Propionibacteria species. 61
10074606 1999
206
[CREST syndrome presenting as pulmonary hypertension]. 61
12555334 1999
207
[From Thibierge-Weissenbach syndrome (1910) to anti-centromere antibodies (1980). Clinical and biological features of scleroderma]. 61
10093661 1999
208
Clinical and immunological characterization of patients with systemic sclerosis overlapping primary biliary cirrhosis: a comparison with patients with systemic sclerosis alone. 61
10063207 1999
209
[Association of extrahepatic autoimmune diseases in primary biliary cirrhosis--clinical statistics and analyses of Japanese and non-Japanese cases]. 61
9796339 1998
210
[A case of idiopathic multiple calcinosis cutis]. 61
10189902 1998
211
Gastrointestinal hemorrhage in patients with systemic sclerosis and CREST syndrome. 61
9732924 1998
212
CREST syndrome: clinical manifestations and dental management. 61
9807098 1998
213
Anti-centromere autoantibody in a patient evolving from a lupus/Sjögren's overlap to the CREST variant of scleroderma. 61
9676778 1998
214
Parafoveal telangiectasia in association with CREST syndrome. 61
9639458 1998
215
[Primary biliary cirrhosis and systemic scleroderma (Reynolds syndrome): apropos of 8 new cases. The contribution of accessory salivary gland biopsy]. 61
9775180 1998
216
[Coincidence of scleroderma and primary biliary cirrhosis. Results of a systematic study of a dermatologic patient sample]. 61
9642556 1998
217
[Seeping gastrointestinal hemorrhage from telangiectasia in CREST syndrome]. 61
9606634 1998
218
Brain involvement in scleroderma: two autopsy cases. 61
9506617 1998
219
Clinical manifestations of systemic sclerosis. 61
9512107 1998
220
Esophagocardioplasty, vagotomy-antrectomy and Roux-en-Y gastrojejunostomy: indication in cases with severe esophageal motor disfunction. 61
9595236 1998
221
Management of severe scleroderma with long-term extracorporeal photopheresis. 61
9621138 1998
222
Epidermal growth factor and gastrin in scleroderma/CREST syndrome. 61
9556923 1998
223
Antinuclear antibodies (ANA) and complement fixing ANA in systemic connective tissue diseases. 61
9561921 1998
224
Immunological characterization of heterochromatin protein p25beta autoantibodies and relationship with centromere autoantibodies and pulmonary fibrosis in systemic scleroderma. 61
9462868 1998
225
A case-control and nerve biopsy study of CREST multiple mononeuropathy. 61
9409360 1997
226
Induction of kinetochore positive and negative micronuclei in V79 cells by N-methyl-N'-nitro-N-nitrosoguanidine: the protective effect of the pyridoindole antioxidant stobadine. 61
9465936 1997
227
Six cases positive for anti-centromere antibodies with ulcer and gangrene in the extremities. 61
9291859 1997
228
[Successful treatment of toe gangrene with moderate-dose steroid therapy in a patient with systemic sclerosis (CREST syndrome)]. 61
9256035 1997
229
[Argon plasma coagulation in endoscopic therapy of CREST syndrome associated upper gastrointestinal hemorrhage]. 61
9281240 1997
230
Calcium carbonate apatite deposition in the cervical spine with associated vertebral destruction. Case report. 61
9171183 1997
231
Image of the month. CREST syndrome: calcinosis cutis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasis. 61
9178667 1997
232
Comparison of antinuclear antibody testing methods: immunofluorescence assay versus enzyme immunoassay. 61
9067653 1997
233
[Idiopathic portal hypertension, multiple focal nodular hepatic hyperplasia, the CREST syndrome and protein S deficiency]. 61
9090984 1997
234
[Primary pulmonary hypertension: a rare but often fatal complication of Crest syndrome]. 61
9092028 1997
235
[The case of a 27-year old patient's survival with CREST syndrome]. 61
9591458 1997
236
[CREST syndrome]. 61
9277943 1997
237
Prevalence of scleroderma spectrum disorders in the general population of Estonia. 61
9433401 1997
238
Antibodies to membranes of endothelial cells and fibroblasts in scleroderma. 61
8973617 1996
239
Early recurrence or persistence of autoimmune diseases after unmanipulated autologous stem cell transplantation. 61
8896432 1996
240
Positivity for antinuclear antibody in patients with advanced rheumatoid arthritis. 61
8914679 1996
241
[Clinical significance of anti-centromere antibody and anti-CENP-B antibody in sera of patients with primary biliary cirrhosis]. 61
8911074 1996
242
Reversible cardiogenic shock in an angry woman--case report and review of the literature. 61
8689541 1996
243
Familial lichen sclerosus et atrophicus in association with CREST syndrome: a case report. 61
8763444 1996
244
Aerosolized prostacyclin and iloprost in severe pulmonary hypertension. 61
8610951 1996
245
Interchange between collagenous and lymphocytic colitis in severe disease with autoimmune associations requiring colectomy: a case report. 61
8707130 1996
246
[Myelodysplastic syndrome with CREST syndrome successfully treated with metenolone--A case report]. 61
8847810 1996
247
Achalasia-like syndrome as the first manifestation in a patient with CREST syndrome. 61
8724033 1996
248
Calcific constructive pericarditis: a rare complication of CREST syndrome. 61
8849391 1996
249
Selection and use of laboratory tests in the rheumatic diseases. 61
8604722 1996
250
Signal-averaged electrocardiography and echocardiography in the evaluation of myocardial involvement in progressive systemic sclerosis. 61
8682603 1996
251
Image interpretation session: 1995. Case 1. Exogenous lipoid pneumonia superimposed on systemic sclerosis with limited scleroderma (CREST syndrome). 61
10946703 1996
252
The evolution of Raynaud's phenomenon: a longterm prospective study. 61
8835553 1995
253
A case of CREST syndrome associated with sick sinus syndrome. 61
8586765 1995
254
Antibodies to fibrin bound tissue type plasminogen activator in systemic sclerosis. 61
8523346 1995
255
Primary biliary cirrhosis: lung involvement. 61
8544642 1995
256
Wegener's granulomatosis and CREST syndrome--Le Thi Huong D, Gatfosse M et al. 61
7646679 1995
257
Autosomal-recessive neural crest syndrome with albinism, black lock, cell migration disorder of the neurocytes of the gut, and deafness: ABCD syndrome. 61
7778600 1995
258
CREST syndrome: a variant of systemic sclerosis. 61
7761133 1995
259
Antifibrillarin autoantibodies present in systemic sclerosis and other connective tissue diseases interact with similar epitopes. 61
7532674 1995
260
Association of HLA-DR5 (DR11) with systemic sclerosis (scleroderma) in Mexican patients. 61
7774089 1995
261
Wegener's granulomatosis and CREST syndrome. 61
7981999 1994
262
Watermelon stomach in the CREST syndrome. 61
7831185 1994
263
Autonomic dysfunction in diffuse scleroderma vs CREST: an assessment by computerized heart rate variability. 61
7837149 1994
264
[Two patients with positive anticentromere antibody showing different clinical features of CREST syndrome or primary biliary cirrhosis (PBC)]. 61
7967139 1994
265
Clinical correlation of anticentromere antibodies. 61
7835004 1994
266
[Two cases of asymptomatic primary biliary cirrhosis (PBC) accompanied with CREST syndrome]. 61
7974028 1994
267
Anticentromere antibodies (ACA): clinical distribution and disease specificity. 61
7955469 1994
268
[Pulmonary involvement in sclerodermia]. 61
8084431 1994
269
[Detection of antinuclear antibodies and their significance as disease markers]. 61
8022074 1994
270
Gastric telangiectasis: a rare cause of severe blood loss in CREST syndrome. 61
8183780 1994
271
Familial CREST syndrome. 61
8035406 1994
272
Single lung transplantation: a temporal look at rejection, infection, and survival. 61
8304652 1994
273
Significance of in vivo pepper-dot epidermal nuclear reactions: correlation with anticentromere antibodies and CREST syndrome. 61
8288796 1994
274
[Vascular gastric anomalies, CREST syndrome and primary biliary cirrhosis: efficacy of ethinyl estradiol-norethisterone combination]. 61
7875423 1994
275
[Association of autoimmune disease in primary biliary cirrhosis]. 61
8114302 1994
276
[Correlation between various autoantibodies in scleroderma patients and their clinical features]. 61
8124613 1993
277
Annular bullous eruption in a patient with the CREST syndrome, primary biliary cirrhosis, and Sjögren's syndrome. 61
8408804 1993
278
Bilateral optic neuropathy associated with the crest variant of scleroderma. 61
8142747 1993
279
[Diagnostic role of the pharmacologic stress with dipyridamole in reduced coronary reserve associated with CREST syndrome. Description of 2 cases]. 61
8247311 1993
280
CREST syndrome with pericardial but not peripheral calcinosis. 61
8257217 1993
281
Oral problems associated with CREST syndrome: a case report. 61
8217427 1993
282
Silicone-reactive disorder: a new autoimmune disease caused by immunostimulation and superantigens. 61
8289701 1993
283
[Brucella infective endocarditis on sclerodermic mitral valve. Report of a case]. 61
8235016 1993
284
Sclerotherapy as treatment of recurrent bleeding from upper gastrointestinal telangiectasia in CREST syndrome. 61
8348284 1993
285
Anticentromere antibodies in subjects with no apparent connective tissue disease. 61
8215621 1993
286
The effects of warfarin on calcinosis in a patient with systemic sclerosis. 61
8371227 1993
287
Large vessel occlusive disease associated with CREST syndrome and scleroderma. 61
8323401 1993
288
[Prepatellar acute calcifying periarthritis disclosing Crest syndrome]. 61
8124285 1993
289
Occurrence of primary biliary cirrhosis, CREST syndrome and Sjögren's syndrome in a patient with HTLV-I-associated myelopathy. 61
8509804 1993
290
Familial scleroderma: HLA antigens and autoantibodies. 61
8461929 1993
291
Clinicopathological significance of cutaneous epidermal nuclear staining by direct immunofluorescence. 61
8320361 1993
292
[Simultaneous measurement of kinetochore protein and DNA by flow cytometry]. 61
8489280 1993
293
Prominent telangiectasia associated with marked bleeding in CREST syndrome. 61
8478499 1993
294
Soft-tissue chondroma as a cause of calcinosis in a patient with CREST syndrome. 61
8457459 1993
295
[The CREST syndrome and Hashimoto's thyroiditis, apropos a case seen in our primary care center]. 61
8452984 1993
296
Silicon and silicone: theoretical and clinical implications of breast implants. 61
8441826 1993
297
A case of progressive systemic sclerosis associated with sarcoidosis and esophageal adenocarcinoma. 61
8482751 1993
298
Geographical clustering of scleroderma in a rural area in the province of Rome. 61
8453796 1993
299
Anti-centromere antibody and CREST syndrome in patients with primary biliary cirrhosis. 61
1284406 1992
300
[Anti-centromere antibodies. Study of 67 positive sera]. 61
1344922 1992
301
Short- and long-term hemodynamic effects of captopril in patients with pulmonary hypertension and selected connective tissue disease. 61
1424860 1992
302
Acute calcific periarthritis in scleroderma. 61
1334516 1992
303
Long-term follow-up study of 164 patients with definite systemic sclerosis: classification considerations. 61
1458783 1992
304
Gastrointestinal transit times of radiolabeled meal in progressive systemic sclerosis. 61
1324142 1992
305
Fulminant dermatomyositis after removal of a cancer. 61
1401500 1992
306
Studies of the microvascular endothelium in uninvolved skin of patients with systemic sclerosis: direct evidence for a generalized microangiopathy. 61
1610706 1992
307
Systemic sclerosis. 61
1621127 1992
308
Characterization of centromere arrangements and test for random distribution in G0, G1, S, G2, G1, and early S' phase in human lymphocytes. 61
1551672 1992
309
Calcinosis and the anticentromere antibody: its clinical, radiological and immunogenetic aspects. 61
1730111 1992
310
A microchromosome derived from chromosome 11 in a patient with the CREST syndrome of scleroderma. 61
1582251 1992
311
A case of CREST syndrome with rapidly progressive liver damage. 61
1568046 1992
312
[Indirect immunofluorescence method using anticentromere antibodies and its application in the study of chromosome aberrations in tumor cells]. 61
1838965 1991
313
Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease. 61
1746473 1991
314
CREST-associated multiple intracranial aneurysms and bilateral optic neuropathies. 61
1838540 1991
315
A double blind, randomised, multicentre comparison of two doses of intravenous iloprost in the treatment of Raynaud's phenomenon secondary to connective tissue diseases. 61
1722967 1991
316
Non-invasive evaluation of long-term cardiac effects of captopril in systemic sclerosis. 61
1895042 1991
317
Lung function abnormalities and decline of spirometry in scleroderma: an overrated danger? 61
1924047 1991
318
[Absence of microalbuminuria in CREST syndrome]. 61
1830658 1991
319
[Primary biliary cirrhosis]. 61
2057739 1991
320
[Pulmonary arterial hypertension and systemic diseases]. 61
2057730 1991
321
Scleroderma and central nervous system vasculitis. 61
2003313 1991
322
Micronuclei with kinetochores in human melanoma cells and rectal carcinomas. 61
1671688 1991
323
[Clinical report of a case of CREST syndrome]. 61
1827381 1991
324
[The titers and complement-activating abilities of anticentromere antibody in systemic sclerosis, other connective tissue diseases, and other related conditions]. 61
2072581 1991
325
[Vital findings in capillary microscopy in collagen diseases]. 61
1788702 1991
326
Serological profiles as prognostic clues for progressive systemic scleroderma: the Italian experience. 61
1769409 1991
327
Pulmonary hypertension in connective tissue disease. Report of three cases and review of the literature. 61
1835119 1991
328
Idiotypic analysis of human anti-topoisomerase I autoantibodies. 61
1660312 1991
329
[Primary biliary cirrhosis. The clinical experience in 31 patients]. 61
2152667 1990
330
[Reynolds syndrome: primary biliary cirrhosis associated with CREST syndrome]. 61
2090176 1990
331
[Pulmonary involvement in a case of CREST syndrome]. 61
2255419 1990
332
A case of nodular regenerative hyperplasia of the liver, CREST syndrome, and primary biliary cirrhosis. 61
2253925 1990
333
Renal involvement in scleroderma. 61
2084079 1990
334
Clinical and laboratory profile of systemic sclerosis in northern India. 61
2084078 1990
335
Nifedipine and prazosin in the management of pulmonary hypertension in CREST syndrome. 61
2394157 1990
336
The analysis of antinuclear and antinucleolar autoantibodies of scleroderma by radioimmunoprecipitation assays. 61
2403405 1990
337
[The significance of autoantibodies coexisting with anti-centromere antibodies in sera of patients with primary biliary cirrhosis]. 61
2232249 1990
338
The effect of diltiazem on calcinosis in a patient with the CREST syndrome. 61
2390132 1990
339
Pericardial tamponade and limited cutaneous systemic sclerosis (CREST syndrome) 61
2379049 1990
340
[Immunoserological area--with special reference to the current topics on antinuclear antibodies]. 61
2205741 1990
341
Pulmonary diffusing capacity disturbances are related to nailfold capillary changes in patients with Raynaud's phenomenon with and without an underlying connective tissue disease. 61
2368791 1990
342
Autoantibodies to chromosomal domains in rheumatic diseases. 61
1967042 1990
343
The pulmonary pathologic manifestations of the CREST syndrome. 61
2186993 1990
344
[Autoimmune hemolytic anemia and CREST syndrome]. 61
2201843 1990
345
CREST syndrome: nodular regenerative hyperplasia of the liver and primary biliary cirrhosis an overlap syndrome? 61
2338281 1990
346
Early detection of connective tissue disease in patients with Raynaud's phenomenon. 61
2406802 1990
347
Scleroderma after silicone augmentation mammoplasty. A report of 2 cases. 61
2300858 1990
348
Microvasculature in systemic sclerosis. 61
2406812 1990
349
[Anti-Scl-70 antibodies in systemic scleroderma]. 61
2111650 1990
350
Cytotoxic effects of sera from patients with systemic scleroderma: comparison of three different in vitro methods. 61
2349435 1990
351
Arthroscopic resection of olecranon and prepatellar bursae. 61
2363785 1990
352
The diagnostic value of several immunological tests for anti-nuclear antibody in predicting the development of connective tissue disease in patients presenting with Raynaud's phenomenon. 61
2515974 1989
353
[Frequency of anti-centromere antibodies in the anti-mitochondrial antibody positive sera]. 61
2614966 1989
354
Lung function in patients with systemic lupus erythematosus and persistent chest symptoms. 61
2511998 1989
355
Nodular regenerative hyperplasia of the liver, CREST syndrome and primary biliary cirrhosis: an overlap syndrome? 61
2583572 1989
356
[Generalized sclerosis (scleroderma) in children]. 61
2695112 1989
357
[The CREST syndrome associated with the sicca syndrome]. 61
2491051 1989
358
Anticentromere antibody positive CREST syndrome associated with polyarthritis, renal impairment and mixed cryoglobulinaemia. 61
2805613 1989
359
[Two cases of CREST syndrome complicated with primary biliary cirrhosis and their correlation with HLA-DR]. 61
2592832 1989
360
[Angiopathy caused by vibration and CREST syndrome: beware of hidden pathologies!]. 61
2622414 1989
361
[Antinuclear antibodies in primary biliary cirrhosis]. 61
2680726 1989
362
Organ manifestations in 100 patients with progressive systemic sclerosis: a comparison between the CREST syndrome and diffuse scleroderma. 61
2787182 1989
363
Pulmonary hypertension in the CREST syndrome: variant of systemic sclerosis (scleroderma)--a case report. 61
2757266 1989
364
Marker antibodies in scleroderma and polymyositis: clinical associations. 61
2547546 1989
365
Induction of kinetochore positive and negative micronuclei in V79 cells by the alkylating agent diethylsulphate. 61
2659936 1989
366
Lumbosacral plexopathy in a woman with CREST syndrome and vasculitis. 61
2541729 1989
367
[Nodular regenerative hyperplasia of the liver associated with a CREST syndrome with multiorgan involvement]. 61
2577486 1989
368
Chromosome segregation from cell hybrids. VI. Centromeres of both parental chromosome sets stain with antikinetochore antibody. 61
2663641 1989
369
[Generalized morphea-like progressive systemic sclerosis with anticentromere antibodies and eosinophilic cellulitis]. 61
2614990 1989
370
Chromatin bodies in multidrug resistant hybrid cells have centromeres and originate from homogeneously staining regions. 61
2665631 1989
371
Digital nerve calcification in CREST syndrome. 61
2539407 1989
372
[Anti-Scl-70 and anti-centromere autoantibodies. Biological markers of 2 forms of systemic scleroderma]. 61
2522207 1989
373
[Pulmonary hypertension in diffuse scleroderma and the CREST syndrome]. 61
2798573 1989
374
Antinuclear antibodies detected by indirect immunofluorescence on HEp2 cells and by immunoblotting in patients with systemic sclerosis. 61
2491600 1989
375
Ketanserin: an effective treatment regimen for digital ischaemia in systemic sclerosis. 61
2734594 1989
376
Cineradiography identifies esophageal candidiasis in progressive systemic sclerosis. 61
2706818 1989
377
[New advances in rheumatology]. 61
2491405 1989
378
Hemoptysis secondary to respiratory tract telangiectasias in CREST syndrome. 61
3230574 1988
379
Piebaldism-Waardenburg syndrome: histopathologic evidence for a neural crest syndrome. 61
3228147 1988
380
CREST syndrome: a variant of progressive systemic sclerosis, associated with interstitial pulmonary fibrosis and malignancy. 61
3420453 1988
381
Normal cardiovascular autonomic function in patients with systemic sclerosis (CREST variant). 61
3415366 1988
382
Coexistence of CREST syndrome and primary biliary cirrhosis. Serological studies of two cases. 61
3172118 1988
383
[Differential diagnosis of Osler's telangiectasia and the CREST syndrome: significance of centromere antibodies]. 61
3403273 1988
384
[The CREST syndrome. Apropos of a case with Wolff-Parkinson-White type B syndrome]. 61
3061092 1988
385
Mononeuritis multiplex: the yield of evaluations for occult rheumatic diseases. 61
2835572 1988
386
[The CREST syndrome]. 61
3393644 1988
387
Evaluation of muscular lesions in connective tissue diseases: thallium 201 muscular scans. 61
3372758 1988
388
Prospective study of the evolution of Raynaud's phenomenon. 61
3261127 1988
389
Serum and urinary aminoterminal type III procollagen peptide in progressive systemic sclerosis: relationship to sclerodermal involvement, serum hyaluronan and urinary collagen metabolites. 61
3259985 1988
390
The CREST syndrome and sarcoidosis. Another example of an overlap syndrome. 61
3381024 1988
391
Clinical associations of anticentromere antibodies and antibodies to topoisomerase I. A study of 355 patients. 61
2833902 1988
392
Renal vascular histology and morphometry in systemic sclerosis. A case-control autopsy study. 61
3358801 1988
393
[Anticentromere antibodies in rheumatoid polyarthritis with Sjögren syndrome, without the elements of the CREST syndrome]. 61
3259719 1988
394
Clinical correlations and prognosis based on serum autoantibodies in patients with systemic sclerosis. 61
3348823 1988
395
[Cardiac involvement in scleroderma]. 61
3073274 1988
396
Primary biliary cirrhosis and the CREST syndrome: new terminology? 61
3338709 1988
397
Analysis of double minutes and double minute-like chromatin in human and murine tumor cells using antikinetochore antibodies. 61
3275490 1988
398
Significance of anticentromere antibody in idiopathic Raynaud's syndrome. 61
3314499 1987
399
Frequency, levels, and significance of blood eosinophilia in systemic sclerosis, localized scleroderma, and eosinophilic fasciitis. 61
3668010 1987
400
Vasculitis in systemic sclerosis: association with Sjögren's syndrome and the CREST syndrome variant. 61
3430523 1987
401
Immunoglobulin G subclass distribution of autoantibodies in systemic sclerosis, primary biliary cirrhosis, and overlap syndromes. 61
3115201 1987
402
[A case of CREST syndrome with reversible hypoventilatory respiratory failure probably caused by respiratory muscle weakness]. 61
3438781 1987
403
Cutaneous sclerosis localized to one limb after immobilization in a patient with CREST syndrome. 61
3625655 1987
404
Severe subcutaneous calcification in the 'CREST' syndrome: evidence of high turnover of calcific deposits. 61
3828674 1987
405
Primary biliary cirrhosis and CREST-syndrome, a classical but rare association. 61
3608278 1987
406
[The CREST syndrome]. 61
3596643 1987
407
[Cardiac repercussions in the CREST syndrome]. 61
2961963 1987
408
Primary biliary cirrhosis and the CREST syndrome: a report of 22 cases. 61
3423208 1987
409
Natural killer cell activity of peripheral blood mononuclear cells from patients with various forms of systemic scleroderma. 61
3814504 1987
410
Comparing HEp-2 cell line with rat liver in routine screening test for antinuclear and antinucleolar autoantibodies in autoimmune diseases. 61
3326434 1987
411
Barrett's metaplasia and adenocarcinoma of the esophagus in scleroderma. 61
3799692 1987
412
[Reynolds' syndrome: the combination of scleroderma of CREST syndrome type and primary biliary cirrhosis]. 61
3674670 1987
413
[Anti-centromere antibody (ACA) and its significance for the diagnosis of CREST syndrome]. 61
3494576 1986
414
Characterization of a polypeptide associated with coated vesicles and the cytoskeleton which is recognized by a CREST serum. 61
2875895 1986
415
[The CREST syndrome. Apropos of a case]. 61
3786917 1986
416
Anticentromere antibody in localized scleroderma. 61
3534010 1986
417
A highly conserved 72,000 dalton centromeric antigen reactive with autoantibodies from patients with progressive systemic sclerosis. 61
3531335 1986
418
Diagnostic significance of nailfold capillary patterns in patients with Raynaud's phenomenon. An analysis of patterns discriminating patients with and without connective tissue disease. 61
3735277 1986
419
[The cold test in the CREST syndrome with pulmonary hypertension]. 61
2940574 1986
420
Superior oblique muscle paralysis in the CREST syndrome. 61
3797624 1986
421
Pulmonary hypertension in the CREST syndrome variant of systemic sclerosis. 61
3707629 1986
422
Primary biliary cirrhosis and rheumatic diseases: a clinical, immunological and immunogenetical study. 61
3488154 1986
423
Bronchoalveolar lavage analysis of interstitial lung disease in CREST syndrome. 61
3731570 1986
424
Left ventricular dysfunction induced by cold exposure in patients with systemic sclerosis. 61
3953616 1986
425
Nuclear antigens recognized by antibodies present in liver disease sera. 61
3516468 1986
426
Centromere pattern in different mouse seminiferous tubule cells. 61
3542398 1986
427
Sclerodactyly, CREST syndrome, proximal scleroderma. 61
3954464 1986
428
Long-term griseofulvin treatment for progressive systemic sclerosis. 61
3823792 1986
429
Noninvasive evaluation of cardiac dysrhythmias, and their relationship with multisystemic symptoms, in progressive systemic sclerosis patients. 61
4063000 1985
430
[Hemorrhagic hereditary telangiectasia and CREST syndrome]. 61
4079553 1985
431
The demonstration of the spindle fiber attachments in the amphibian liver and sperm nuclei by the sera from scleroderma patients. 61
3879774 1985
432
Modulatory effect of sera from scleroderma patients on lymphocyte-induced angiogenesis. 61
2413869 1985
433
Anticytoskeletal autoantibodies in the connective tissue diseases. 61
4040759 1985
434
[Anti-centromere antibody, biological marker of the CREST syndrome as distinct from scleroderma]. 61
2931679 1985
435
Antinuclear antibodies in progressive systemic sclerosis. 61
3902296 1985
436
Pulmonary involvement in systemic sclerosis (scleroderma). 61
4015723 1985
437
Association of anti-centromere and anti-Scl 70 antibodies in scleroderma. Report of two cases. 61
3874966 1985
438
Anticentromere antibody and immunoglobulin allotypes in scleroderma. 61
3883903 1985
439
Evaluation of methods for detection of anticentromere antibodies and other antinuclear antibodies. 61
3882784 1985
440
Pulmonary vascular response during Raynaud's phenomenon in progressive systemic sclerosis. 61
3970048 1985
441
Evolution of primary Raynaud's phenomenon (Raynaud's disease) to connective tissue disease. 61
3871330 1985
442
[Centromere antibodies and antibodies against Scl 70 nucleoprotein in progressive systemic scleroderma. Diagnostic and prognostic significance]. 61
3880700 1985
443
Epistaxis secondary to Crest syndrome: a case report. 61
4012832 1985
444
Characterisation of centromere (kinetochore) antigen reactive with sera of patients with a scleroderma variant (CREST syndrome). 61
6524984 1984
445
Detection of antilymphocyte antibodies in patients with scleroderma using three different techniques. 61
6441668 1984
446
Clinical and serological comparison of 17 chronic progressive systemic sclerosis (PSS) and 17 CREST syndrome patients matched for sex, age, and disease duration. 61
6335385 1984
447
The CREST syndrome--successful reduction of pulmonary hypertension by captopril. 61
6387690 1984
448
The anticentromere antibody: disease specificity and clinical significance. 61
6384675 1984
449
Myocardial function and perfusion in the CREST syndrome variant of progressive systemic sclerosis. Exercise radionuclide evaluation and comparison with diffuse scleroderma. 61
6475990 1984
450
In vitro complement activation by antinuclear antibodies in the epidermis from patients with systemic sclerosis. 61
6380559 1984
451
CREST syndrome: a benign entity? 61
6465921 1984
452
Craniovertebral lesions in patient with CREST syndrome. 61
6429774 1984
453
Factors predicting development of renal involvement in progressive systemic sclerosis. 61
6372452 1984
454
[Vital microscopy of nailfold capillaries in progressive scleroderma in relation to the clinical picture]. 61
6730614 1984
455
Oral and gingival changes in systemic sclerosis (scleroderma). 61
6584594 1984
456
Lowered angiogeneic capability of peripheral blood lymphocytes in progressive systemic sclerosis (scleroderma). 61
6199433 1984
457
Clinical and laboratory associations of anticentromere antibody in patients with progressive systemic sclerosis. 61
6607734 1984
458
[Clinical significance of antinuclear antibodies in progressive systemic sclerosis]. 61
6366619 1984
459
Circulating anticoagulant in CREST syndrome. 61
6697068 1984
460
Hereditary hemorrhagic telangiectasia versus CREST syndrome: can serology aid diagnosis? 61
6609175 1984
461
A long-term longitudinal study of anticentromere antibodies. 61
6607733 1984
462
[What can be expected of biological tests in scleroderma?]. 61
6335633 1984
463
Speckled pattern antinuclear antibodies resembling anticentromere antibodies. 61
6197978 1984
464
The kinetochore is part of the metaphase chromosome scaffold. 61
6707096 1984
465
Epistaxis secondary to Crest syndrome: a case report. 61
6740754 1984
466
Unloading the right ventricle in the CREST syndrome variant of progressive systemic sclerosis (scleroderma). 61
6231150 1984
467
[Myositis disclosing systemic scleroderma]. 61
6505497 1984
468
[Mixed polyneuropathy in a patient with CREST syndrome]. 61
6322249 1983
469
Pulmonary function in progressive systemic sclerosis. Comparison of CREST syndrome variant with diffuse scleroderma. 61
6628005 1983
470
[The Crest syndrome. Apropos of a case with pericardial effusion and rapidly fatal severe pulmonary hypertension]. 61
6227001 1983
471
Prevalence and clinical correlates of pulmonary arterial hypertension in progressive systemic sclerosis. 61
6859087 1983
472
[Mitral valve calcification associated with CREST syndrome]. 61
6888060 1983
473
[Antinuclear, anti-DNA and anti-lymphocyte antibodies in systemic scleroderma. 62 cases]. 61
6604306 1983
474
Autoantibodies to nonhistone nuclear antigens and their clinical significance. 61
6341205 1983
475
Relapsing organising pneumonitis in a man with primary biliary cirrhosis, CREST syndrome, and chronic pancreatitis. 61
6867988 1983
476
Ultrastructural and crystallographic study of calcifications from a patient with CREST syndrome. 61
6864678 1983
477
[Significance of anti-centromere antibodies. Clinical value]. 61
6348931 1983
478
The iliac crest syndrome. A treatable cause of low-back pain. 61
6222490 1983
479
HLA-DR antigens in progressive systemic sclerosis (scleroderma). 61
6601709 1983
480
Bilateral bicolored irides with Hirschsprung's disease. A neural crest syndrome. 61
6849656 1983
481
Human fibroblasts, a convenient nuclear substrate for detection of anti-nuclear antibodies including anti-centromere antibodies. 61
6414079 1983
482
[Arterial hypertension with secondary hyperaldosteronism, reversible by nifedipine, in systemic scleroderma]. 61
6666913 1983
483
Hemiplegia and peripheral gangrene secondary to large and medium size vessels involvement in C.R.E.S.T. syndrome. 61
7188436 1982
484
The coexistence of rheumatoid arthritis and scleroderma: a case report and review of the literature. 61
7161787 1982
485
[Active chronic hepatitis with incomplete CREST syndrome: value of anticentromere antibodies]. 61
6983991 1982
486
[Anticentromere antibodies. Diagnostic and prognostic value]. 61
6755388 1982
487
Anticentromere antibody and primary pulmonary hypertension. 61
6752406 1982
488
Immunoglobulin M autoantibody to vimentin intermediate filaments. 61
7037855 1982
489
In vitro cytotoxicity of human endothelial cells in polymyalgia rheumatica and giant cell arteritis. 61
7163734 1982
490
Electromyographic findings in various forms of progressive systemic sclerosis. 61
7066037 1982
491
Thyroid disease in progressive systemic sclerosis: increased frequency of glandular fibrosis and hypothyroidism. 61
7283293 1981
492
Progressive systemic sclerosis subgroups: variable pulmonary features. 61
6789634 1981
493
Increased prevalence of DRw3 in the CREST syndrome. 61
6941787 1981
494
[Peptic esophagitis and scleroderma: apropos of a case of the CREST syndrome]. 61
7227754 1981
495
Abnormalities of T lymphocyte subsets in patients with progressive systemic sclerosis (PSS, scleroderma). 61
6450255 1981
496
The CREST syndrome: a distinct serologic entity with anticentromere antibodies. 61
6968511 1980
497
Diversity of antinuclear antibodies in progressive systemic sclerosis. Anti-centromere antibody and its relationship to CREST syndrome. 61
6155920 1980
498
[Reynolds syndrome associated with Sjögren's syndrome]. 61
7383399 1980
499
Hematological abnormalities in scleroderma. A study of 180 cases. 61
6774574 1980
500
[CREST syndrome. Report of 6 cases]. 61
545494 1979
501
The 'CREST' syndrome. Comparison with systemic sclerosis (scleroderma). 61
508020 1979
502
Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma. 61
420706 1979
503
Stimulation of lymphocyte reactivity by a low molecular weight cutaneous antigen in patients with progressive systemic sclerosis (scleroderma). 61
374734 1979
504
The CREST syndrome variant of scleroderma in a mother-daughter pair. 61
748555 1978
505
Pulmonary hypertension in the CREST syndrome variant of progressive systemic sclerosis (scleroderma). 61
848800 1977
506
Histocompatibility antigens in progressive systemic sclerosis (scleroderma). 61
604479 1977
507
Cutaneous antigen-stimulating lymphokine production by lymphocytes of patients with progressive systemic sclerosis (scleroderma). 61
791970 1976
508
[Variability of the clinical picture and the classification of progressive systemic scleroderma]. 61
961080 1976

Variations for Crest Syndrome

Expression for Crest Syndrome

Search GEO for disease gene expression data for Crest Syndrome.

Pathways for Crest Syndrome

GO Terms for Crest Syndrome

Cellular components related to Crest Syndrome according to GeneCards Suite gene sharing:

(showing 9, show less)
# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 10.23 TOP1 SP100 SOX10 SNRNP70 H2AC18 EXOSC10
2 nucleoplasm GO:0005654 10.14 TOP1 SP100 SOX10 SNRNP70 EXOSC10 CENPS
3 chromosome, centromeric region GO:0000775 9.67 CENPS CENPC CENPB CENPA
4 condensed chromosome kinetochore GO:0000777 9.62 CENPS CENPN CENPC CENPA
5 condensed nuclear chromosome kinetochore GO:0000778 9.43 CENPC CENPA
6 condensed nuclear chromosome, centromeric region GO:0000780 9.43 CENPC CENPB CENPA
7 kinetochore GO:0000776 9.35 CENPS CENPQ CENPN CENPC CENPA
8 nuclear pericentric heterochromatin GO:0031618 9.33 CENPC CENPB CENPA
9 chromosome GO:0005694 9.23 TOP1 H2AC18 CENPS CENPQ CENPN CENPC

Biological processes related to Crest Syndrome according to GeneCards Suite gene sharing:

(showing 4, show less)
# Name GO ID Score Top Affiliating Genes
1 chromosome segregation GO:0007059 9.43 TOP1 CENPN CENPC
2 kinetochore assembly GO:0051382 9.26 CENPS CENPN CENPC CENPA
3 protein side chain deglutamylation GO:0035610 9.16 AGBL3 AGBL2
4 CENP-A containing nucleosome assembly GO:0034080 9.02 CENPS CENPQ CENPN CENPC CENPA

Molecular functions related to Crest Syndrome according to GeneCards Suite gene sharing:

(showing 4, show less)
# Name GO ID Score Top Affiliating Genes
1 DNA binding GO:0003677 9.76 TOP1 SP100 SOX10 H2AC18 CENPS CENPC
2 metallocarboxypeptidase activity GO:0004181 9.26 AGBL3 AGBL2
3 chromatin binding GO:0003682 9.02 TOP1 SOX10 CENPS CENPB CENPA
4 centromeric DNA binding GO:0019237 8.96 CENPC CENPB

Sources for Crest Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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