CCHD
MCID: CRT057
MIFTS: 18

Critical Congenital Heart Disease (CCHD)

Aliases & Classifications for Critical Congenital Heart Disease

MalaCards integrated aliases for Critical Congenital Heart Disease:

Name: Critical Congenital Heart Disease 25
Critical Congenital Heart Defects 25
Cchd 25

Summaries for Critical Congenital Heart Disease

Genetics Home Reference : 25 Critical congenital heart disease (CCHD) is a term that refers to a group of serious heart defects that are present from birth. These abnormalities result from problems with the formation of one or more parts of the heart during the early stages of embryonic development. CCHD prevents the heart from pumping blood effectively or reduces the amount of oxygen in the blood. As a result, organs and tissues throughout the body do not receive enough oxygen, which can lead to organ damage and life-threatening complications. Individuals with CCHD usually require surgery soon after birth.

MalaCards based summary : Critical Congenital Heart Disease, also known as critical congenital heart defects, is related to ebstein anomaly and heart disease. Affiliated tissues include heart, brain and testes.

Related Diseases for Critical Congenital Heart Disease

Diseases related to Critical Congenital Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 ebstein anomaly 11.1
2 heart disease 10.9
3 brain injury 10.1
4 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.8

Symptoms & Phenotypes for Critical Congenital Heart Disease

Drugs & Therapeutics for Critical Congenital Heart Disease

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Pulse Oximeter Screening in Congenital Heart Disease Unknown status NCT02731248
2 The Impact of Implementing a Universal Newborn Screening for Critical Congenital Heart Disease Completed NCT01749059
3 Newborn Screening for Critical Congenital Heart Disease Completed NCT01765205
4 Health-economic Impact of Pulse Oximetry Systematic Screening of Critical Congenital Heart Disease in Asymptomatic Newborns Recruiting NCT03078218 Not Applicable
5 SVR III: Brain Connectome and Neurodevelopmental Outcomes Enrolling by invitation NCT02692443

Search NIH Clinical Center for Critical Congenital Heart Disease

Genetic Tests for Critical Congenital Heart Disease

Anatomical Context for Critical Congenital Heart Disease

MalaCards organs/tissues related to Critical Congenital Heart Disease:

41
Heart, Brain, Testes

Publications for Critical Congenital Heart Disease

Articles related to Critical Congenital Heart Disease:

(show top 50) (show all 211)
# Title Authors Year
1
Survival and Associated Risk Factors for Mortality Among Infants with Critical Congenital Heart Disease in a Developing Country. ( 29756159 )
2018
2
Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease. ( 29572821 )
2018
3
A Modified Algorithm for Critical Congenital Heart Disease Screening Using Pulse Oximetry. ( 29691284 )
2018
4
Revisiting the Approach to Newborn Screening for Critical Congenital Heart Disease. ( 29691283 )
2018
5
The impact of altitude on screening for critical congenital heart disease. ( 29379160 )
2018
6
The neonatal brain in critical congenital heart disease: Insights and future directions. ( 29787864 )
2018
7
Preoperative cerebral hemodynamics from birth to surgery in neonates with critical congenital heart disease. ( 29859676 )
2018
8
Amplitude-Integrated Electroencephalography for Early Recognition of Brain Injury in Neonates with Critical Congenital Heart Disease. ( 30144931 )
2018
9
Is pulse oximetry helpful for the early detection of critical congenital heart disease at high altitude? ( 30095227 )
2018
10
Early Childhood Inpatient Costs of Critical Congenital Heart Disease. ( 30268400 )
2018
11
Antenatal Detection of Treatable Critical Congenital Heart Disease Is Associated with Lower Morbidity and Mortality. ( 30292491 )
2018
12
Effect of Fetal Growth on 1-Year Mortality in Neonates With Critical Congenital Heart Disease. ( 30371167 )
2018
13
Does pulsatility index add value to newborn pulse oximetry screening for critical congenital heart disease? ( 30413491 )
2018
14
Birth Location of Infants with Critical Congenital Heart Disease in California. ( 30415381 )
2018
15
Can echocardiographic screening in the early days of life detect critical congenital heart disease among apparently healthy newborns? ( 30453920 )
2018
16
Cost-effectiveness analysis of pulse oximetry screening for critical congenital heart defects following homebirth and early discharge. ( 30334077 )
2018
17
"There's no acknowledgement of what this does to people": A qualitative exploration of mental health among parents of children with critical congenital heart defects. ( 29345005 )
2018
18
Pulse oximetry screening for critical congenital heart defects. ( 29494750 )
2018
19
Accuracy of Pulse Oximetry Screening for Critical Congenital Heart Defects after Home Birth and Early Postnatal Discharge. ( 29580679 )
2018
20
Public Views on Pulse Oximetry Screening for Critical Congenital Heart Disease. ( 28329450 )
2017
21
Transfer of Neonates with Critical Congenital Heart Disease Within a Regionalized Network. ( 28711963 )
2017
22
The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease. ( 28918207 )
2017
23
Texas Pulse Oximetry Project: A Multicenter Educational and Quality Improvement Project for Implementation of Critical Congenital Heart Disease Screening Using Pulse Oximetry. ( 28264208 )
2017
24
Visuospatial processing in adolescents with critical congenital heart disease: Organization, integration, and implications for academic achievement. ( 28277152 )
2017
25
Gestational Age and Outcomes in Critical Congenital Heart Disease. ( 28885171 )
2017
26
The association of maternal lymphatic markers and critical congenital heart defects in the fetus-A population based case-control study. ( 28323386 )
2017
27
Audit of pulse oximetry screening for critical congenital heart disease (CCHD) in newborns. ( 29479241 )
2017
28
Effectiveness of the critical congenital heart disease screening program for early diagnosis of cardiac abnormalities in newborn infants. ( 28917066 )
2017
29
The role of palliative care in critical congenital heart disease. ( 28189331 )
2017
30
Cost and Cost-Effectiveness Assessments of Newborn Screening for Critical Congenital Heart Disease Using Pulse Oximetry: A Review. ( 29376140 )
2017
31
A Multicenter Initiative for Critical Congenital Heart Disease Newborn Screening in Texas Neonatal Intensive Care Units. ( 28212589 )
2017
32
A National Call to Action-Improving the Detection of Critical Congenital Heart Disease. ( 28129863 )
2017
33
Should New Zealand introduce nationwide pulse oximetry screening for the detection of critical congenital heart disease in newborn infants? ( 28081558 )
2017
34
Perfusion index in healthy newborns during critical congenital heart disease screening at 24 hours: retrospective observational study from the USA. ( 29273653 )
2017
35
Critical congenital heart disease screening with a pulse oximetry in neonates. ( 28672762 )
2017
36
The Success of State Newborn Screening Policies for Critical Congenital Heart Disease. ( 29209703 )
2017
37
Critical Congenital Heart Disease Screening in NICU: Need for Revision and Standardization. ( 28614866 )
2017
38
Using State Birth Defects Registries to Evaluate Regional Critical Congenital Heart Disease Newborn Screening. ( 29152920 )
2017
39
An update work of pulse oximetry screening for detecting critical congenital heart disease in the newborn. ( 29731786 )
2017
40
Pulse oximetry is a feasible method for detecting neonatal critical congenital heart disease. ( 28235129 )
2017
41
A Post-operative Feeding Protocol to Improve Outcomes for Neonates With Critical Congenital Heart Disease. ( 28063770 )
2017
42
Critical Congenital Heart Disease Newborn Screening Implementation: Lessons Learned. ( 28092064 )
2017
43
CDC Grand Rounds: Newborn Screening for Hearing Loss and Critical Congenital Heart Disease. ( 28837548 )
2017
44
The limitations of pulse oximetry for critical congenital heart disease screening in the neonatal intensive care units. ( 28075515 )
2017
45
Erratum to: Critical Congenital Heart Disease Newborn Screening Implementation: Lessons Learned. ( 28477067 )
2017
46
Retinovascular findings in newborns with critical congenital heart disease: A case series. ( 28504505 )
2017
47
Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths. ( 29209720 )
2017
48
Pulse oximetry screening in newborns to enhance detection of critical congenital heart disease. ( 29479265 )
2017
49
Pulse oximetry screening for critical congenital heart defects: a European consensus statement. ( 30169211 )
2017
50
Neonates with critical congenital heart defects: Impact of fetal diagnosis on immediate and short-term outcomes. ( 28566819 )
2017

Variations for Critical Congenital Heart Disease

Expression for Critical Congenital Heart Disease

Search GEO for disease gene expression data for Critical Congenital Heart Disease.

Pathways for Critical Congenital Heart Disease

GO Terms for Critical Congenital Heart Disease

Sources for Critical Congenital Heart Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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