MCID: CRT057
MIFTS: 18

Critical Congenital Heart Disease

Aliases & Classifications for Critical Congenital Heart Disease

MalaCards integrated aliases for Critical Congenital Heart Disease:

Name: Critical Congenital Heart Disease 25
Critical Congenital Heart Defects 25
Cchd 25

Summaries for Critical Congenital Heart Disease

Genetics Home Reference : 25 Critical congenital heart disease (CCHD) is a term that refers to a group of serious heart defects that are present from birth. These abnormalities result from problems with the formation of one or more parts of the heart during the early stages of embryonic development. CCHD prevents the heart from pumping blood effectively or reduces the amount of oxygen in the blood. As a result, organs and tissues throughout the body do not receive enough oxygen, which can lead to organ damage and life-threatening complications. Individuals with CCHD usually require surgery soon after birth.

MalaCards based summary : Critical Congenital Heart Disease, also known as critical congenital heart defects, is related to ebstein anomaly and heart disease. Affiliated tissues include heart, brain and testes.

Related Diseases for Critical Congenital Heart Disease

Diseases related to Critical Congenital Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 ebstein anomaly 11.0
2 heart disease 10.8
3 aging 10.0
4 brain injury 10.0
5 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.7
6 cerebritis 9.7

Graphical network of the top 20 diseases related to Critical Congenital Heart Disease:



Diseases related to Critical Congenital Heart Disease

Symptoms & Phenotypes for Critical Congenital Heart Disease

Drugs & Therapeutics for Critical Congenital Heart Disease

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Pulse Oximeter Screening in Congenital Heart Disease Unknown status NCT02731248
2 The Impact of Implementing a Universal Newborn Screening for Critical Congenital Heart Disease Completed NCT01749059
3 Newborn Screening for Critical Congenital Heart Disease Completed NCT01765205
4 SVR III: Brain Connectome and Neurodevelopmental Outcomes Enrolling by invitation NCT02692443
5 Health-economic Impact of Pulse Oximetry Systematic Screening of Critical Congenital Heart Disease in Asymptomatic Newborns Not yet recruiting NCT03078218 Not Applicable
6 Critical Congenital Heart Defect (CHD) Outcomes in Children Terminated NCT00208689

Search NIH Clinical Center for Critical Congenital Heart Disease

Genetic Tests for Critical Congenital Heart Disease

Anatomical Context for Critical Congenital Heart Disease

MalaCards organs/tissues related to Critical Congenital Heart Disease:

41
Heart, Brain, Testes

Publications for Critical Congenital Heart Disease

Articles related to Critical Congenital Heart Disease:

(show top 50) (show all 156)
# Title Authors Year
1
Survival and Associated Risk Factors for Mortality Among Infants with Critical Congenital Heart Disease in a Developing Country. ( 29756159 )
2018
2
Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease. ( 29572821 )
2018
3
A Modified Algorithm for Critical Congenital Heart Disease Screening Using Pulse Oximetry. ( 29691284 )
2018
4
Revisiting the Approach to Newborn Screening for Critical Congenital Heart Disease. ( 29691283 )
2018
5
The impact of altitude on screening for critical congenital heart disease. ( 29379160 )
2018
6
The neonatal brain in critical congenital heart disease: Insights and future directions. ( 29787864 )
2018
7
Preoperative cerebral hemodynamics from birth to surgery in neonates with critical congenital heart disease. ( 29859676 )
2018
8
Public Views on Pulse Oximetry Screening for Critical Congenital Heart Disease. ( 28329450 )
2017
9
Transfer of Neonates with Critical Congenital Heart Disease Within a Regionalized Network. ( 28711963 )
2017
10
The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease. ( 28918207 )
2017
11
Texas Pulse Oximetry Project: A Multicenter Educational and Quality Improvement Project for Implementation of Critical Congenital Heart Disease Screening Using Pulse Oximetry. ( 28264208 )
2017
12
Visuospatial processing in adolescents with critical congenital heart disease: Organization, integration, and implications for academic achievement. ( 28277152 )
2017
13
Gestational Age and Outcomes in Critical Congenital Heart Disease. ( 28885171 )
2017
14
The association of maternal lymphatic markers and critical congenital heart defects in the fetus-A population based case-control study. ( 28323386 )
2017
15
Audit of pulse oximetry screening for critical congenital heart disease (CCHD) in newborns. ( 29479241 )
2017
16
Effectiveness of the critical congenital heart disease screening program for early diagnosis of cardiac abnormalities in newborn infants. ( 28917066 )
2017
17
The role of palliative care in critical congenital heart disease. ( 28189331 )
2017
18
Cost and Cost-Effectiveness Assessments of Newborn Screening for Critical Congenital Heart Disease Using Pulse Oximetry: A Review. ( 29376140 )
2017
19
A Multicenter Initiative for Critical Congenital Heart Disease Newborn Screening in Texas Neonatal Intensive Care Units. ( 28212589 )
2017
20
A National Call to Action-Improving the Detection of Critical Congenital Heart Disease. ( 28129863 )
2017
21
Should New Zealand introduce nationwide pulse oximetry screening for the detection of critical congenital heart disease in newborn infants? ( 28081558 )
2017
22
Perfusion index in healthy newborns during critical congenital heart disease screening at 24 hours: retrospective observational study from the USA. ( 29273653 )
2017
23
Critical congenital heart disease screening with a pulse oximetry in neonates. ( 28672762 )
2017
24
The Success of State Newborn Screening Policies for Critical Congenital Heart Disease. ( 29209703 )
2017
25
Critical Congenital Heart Disease Screening in NICU: Need for Revision and Standardization. ( 28614866 )
2017
26
Using State Birth Defects Registries to Evaluate Regional Critical Congenital Heart Disease Newborn Screening. ( 29152920 )
2017
27
An update work of pulse oximetry screening for detecting critical congenital heart disease in the newborn. ( 29731786 )
2017
28
Pulse oximetry is a feasible method for detecting neonatal critical congenital heart disease. ( 28235129 )
2017
29
A Post-operative Feeding Protocol to Improve Outcomes for Neonates With Critical Congenital Heart Disease. ( 28063770 )
2017
30
Critical Congenital Heart Disease Newborn Screening Implementation: Lessons Learned. ( 28092064 )
2017
31
CDC Grand Rounds: Newborn Screening for Hearing Loss and Critical Congenital Heart Disease. ( 28837548 )
2017
32
Pulse oximetry screening in newborns to enhance detection of critical congenital heart disease. ( 29479265 )
2017
33
Retinovascular findings in newborns with critical congenital heart disease: A case series. ( 28504505 )
2017
34
Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths. ( 29209720 )
2017
35
The limitations of pulse oximetry for critical congenital heart disease screening in the neonatal intensive care units. ( 28075515 )
2017
36
A novel, more efficient, staged approach for critical congenital heart disease screening. ( 27831548 )
2016
37
Pulse Oximetry Overestimates Oxyhemoglobin in Neonates with Critical Congenital Heart Disease. ( 26800085 )
2016
38
Pulse Oximetry Screening for Critical Congenital Heart Disease after Home Birth and Early Discharge. ( 26746119 )
2016
39
Pulse oximetry screening for critical congenital heart disease in planned out of hospital births and the incidence of critical congenital heart disease in the Plain community. ( 27583398 )
2016
40
Newborn Critical Congenital Heart Disease Screening Using Pulse Oximetry: Nursing Aspects. ( 27603538 )
2016
41
Legal and Ethical Considerations in Allowing Parental Exemptions From Newborn Critical Congenital Heart Disease (CCHD) Screening. ( 26734736 )
2016
42
Pulse oximetry screening: a review of diagnosing critical congenital heart disease in newborns. ( 27468253 )
2016
43
Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Position Statement on Pulse Oximetry Screening in Newborns to Enhance Detection of Critical Congenital Heart Disease. ( 28043739 )
2016
44
Antenatal diagnosis of critical congenital heart disease. Optimal place of delivery is where appropriate care can be delivered. ( 26819268 )
2016
45
Universal Pulse Oximetry Screening for Early Detection of Critical Congenital Heart Disease. ( 27279759 )
2016
46
Development of a Newborn Screening Program for Critical Congenital Heart Disease (CCHD) in Taipei. ( 27073996 )
2016
47
Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury. ( 26902528 )
2016
48
Critical congenital heart disease screening. ( 27390667 )
2016
49
Parents Do Not Always Have to Get Their Way: Why Critical Congenital Heart Disease Screening for Newborns Should Be Mandatory. ( 26734746 )
2016
50
Complications of Long-Term Prostaglandin E1 Use in Newborns With Ductal-Dependent Critical Congenital Heart Disease. ( 26813395 )
2016

Variations for Critical Congenital Heart Disease

Expression for Critical Congenital Heart Disease

Search GEO for disease gene expression data for Critical Congenital Heart Disease.

Pathways for Critical Congenital Heart Disease

GO Terms for Critical Congenital Heart Disease

Sources for Critical Congenital Heart Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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