MCID: CRT057
MIFTS: 18

Critical Congenital Heart Disease

Aliases & Classifications for Critical Congenital Heart Disease

MalaCards integrated aliases for Critical Congenital Heart Disease:

Name: Critical Congenital Heart Disease 26
Critical Congenital Heart Defects 26
Cchd 26

Summaries for Critical Congenital Heart Disease

Genetics Home Reference : 26 Critical congenital heart disease (CCHD) is a term that refers to a group of serious heart defects that are present from birth. These abnormalities result from problems with the formation of one or more parts of the heart during the early stages of embryonic development. CCHD prevents the heart from pumping blood effectively or reduces the amount of oxygen in the blood. As a result, organs and tissues throughout the body do not receive enough oxygen, which can lead to organ damage and life-threatening complications. Individuals with CCHD usually require surgery soon after birth.

MalaCards based summary : Critical Congenital Heart Disease, also known as critical congenital heart defects, is related to ebstein anomaly and heart disease. Affiliated tissues include heart, brain and testes.

Related Diseases for Critical Congenital Heart Disease

Diseases related to Critical Congenital Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 ebstein anomaly 11.2
2 heart disease 10.9
3 brain injury 10.1
4 disease of mental health 10.0
5 acute insulin response 9.8
6 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.8

Graphical network of the top 20 diseases related to Critical Congenital Heart Disease:



Diseases related to Critical Congenital Heart Disease

Symptoms & Phenotypes for Critical Congenital Heart Disease

Drugs & Therapeutics for Critical Congenital Heart Disease

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Pulse Oximeter Screening in Congenital Heart Disease Unknown status NCT02731248
2 The Impact of Implementing a Universal Newborn Screening for Critical Congenital Heart Disease Completed NCT01749059
3 Newborn Screening for Critical Congenital Heart Disease Completed NCT01765205
4 Health-economic Impact of Pulse Oximetry Systematic Screening of Critical Congenital Heart Disease in Asymptomatic Newborns Recruiting NCT03078218 Not Applicable
5 SVR III: Brain Connectome and Neurodevelopmental Outcomes Enrolling by invitation NCT02692443
6 Critical Congenital Heart Defect (CHD) Outcomes in Children Terminated NCT00208689

Search NIH Clinical Center for Critical Congenital Heart Disease

Genetic Tests for Critical Congenital Heart Disease

Anatomical Context for Critical Congenital Heart Disease

MalaCards organs/tissues related to Critical Congenital Heart Disease:

42
Heart, Brain, Testes

Publications for Critical Congenital Heart Disease

Articles related to Critical Congenital Heart Disease:

(show top 50) (show all 223)
# Title Authors Year
1
The neonatal brain in critical congenital heart disease: Insights and future directions. ( 29787864 )
2019
2
Antenatal Detection of Treatable Critical Congenital Heart Disease Is Associated with Lower Morbidity and Mortality. ( 30292491 )
2019
3
Pulse oximetry screening for critical congenital heart disease: a comparative study of cohorts over 11 years ( 30332903 )
2019
4
Does pulsatility index add value to newborn pulse oximetry screening for critical congenital heart disease? ( 30413491 )
2019
5
Birth Location of Infants with Critical Congenital Heart Disease in California. ( 30415381 )
2019
6
Impact of Family Socioeconomic Status on Health-Related Quality of Life in Children With Critical Congenital Heart Disease. ( 30563422 )
2019
7
Brain microstructural development in neonates with critical congenital heart disease: An atlas-based diffusion tensor imaging study. ( 30677732 )
2019
8
Actions in Support of Newborn Screening for Critical Congenital Heart Disease - United States, 2011-2018. ( 30730872 )
2019
9
Brain and CSF Volumes in Fetuses and Neonates with Antenatal Diagnosis of Critical Congenital Heart Disease: A Longitudinal MRI Study. ( 30923087 )
2019
10
Should we start a nationwide screening program for critical congenital heart disease in Turkey? A pilot study on four centres with different altitudes. ( 30957737 )
2019
11
Perfusion index cannot be currently recommended as an additional newborn screen for critical congenital heart disease: more data needed. ( 30971399 )
2019
12
Oxygen Saturation and Perfusion Index-Based Enhanced Critical Congenital Heart Disease Screening. ( 31003242 )
2019
13
Newborn Screening Pulse Oximetry to Detect Critical Congenital Heart Disease: A Follow-Up Survey of Current Practice at Army, Navy and Air Force Hospitals. ( 31090912 )
2019
14
Cost-effectiveness analysis of pulse oximetry screening for critical congenital heart defects following homebirth and early discharge. ( 30334077 )
2019
15
Screening newborns for critical congenital heart defects. ( 30586044 )
2019
16
Pulse Oximetry Screening for Critical Congenital Heart Defects in Newborns. ( 30932460 )
2019
17
Amplitude-Integrated Electroencephalography for Early Recognition of Brain Injury in Neonates with Critical Congenital Heart Disease. ( 30144931 )
2018
18
Perioperative neonatal brain injury is associated with worse school-age neurodevelopment in children with critical congenital heart disease. ( 29572821 )
2018
19
Revisiting the Approach to Newborn Screening for Critical Congenital Heart Disease. ( 29691283 )
2018
20
A Modified Algorithm for Critical Congenital Heart Disease Screening Using Pulse Oximetry. ( 29691284 )
2018
21
Survival and Associated Risk Factors for Mortality Among Infants with Critical Congenital Heart Disease in a Developing Country. ( 29756159 )
2018
22
Preoperative cerebral hemodynamics from birth to surgery in neonates with critical congenital heart disease. ( 29859676 )
2018
23
Is pulse oximetry helpful for the early detection of critical congenital heart disease at high altitude? ( 30095227 )
2018
24
Early Childhood Inpatient Costs of Critical Congenital Heart Disease. ( 30268400 )
2018
25
Effect of Fetal Growth on 1-Year Mortality in Neonates With Critical Congenital Heart Disease. ( 30371167 )
2018
26
Can echocardiographic screening in the early days of life detect critical congenital heart disease among apparently healthy newborns? ( 30453920 )
2018
27
Visual-spatial processing style is associated with psychopathology in adolescents with critical congenital heart disease. ( 30585527 )
2018
28
Visuospatial processing in adolescents with critical congenital heart disease: Organization, integration, and implications for academic achievement. ( 28277152 )
2018
29
Critical congenital heart disease screening with a pulse oximetry in neonates. ( 28672762 )
2018
30
The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease. ( 28918207 )
2018
31
The impact of altitude on screening for critical congenital heart disease. ( 29379160 )
2018
32
"There's no acknowledgement of what this does to people": A qualitative exploration of mental health among parents of children with critical congenital heart defects. ( 29345005 )
2018
33
Pulse oximetry screening for critical congenital heart defects. ( 29494750 )
2018
34
Accuracy of Pulse Oximetry Screening for Critical Congenital Heart Defects after Home Birth and Early Postnatal Discharge. ( 29580679 )
2018
35
An update work of pulse oximetry screening for detecting critical congenital heart disease in the newborn. ( 29731786 )
2017
36
A novel, more efficient, staged approach for critical congenital heart disease screening. ( 27831548 )
2017
37
Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Position Statement on Pulse Oximetry Screening in Newborns to Enhance Detection of Critical Congenital Heart Disease. ( 28043739 )
2017
38
A Post-operative Feeding Protocol to Improve Outcomes for Neonates With Critical Congenital Heart Disease. ( 28063770 )
2017
39
The limitations of pulse oximetry for critical congenital heart disease screening in the neonatal intensive care units. ( 28075515 )
2017
40
Should New Zealand introduce nationwide pulse oximetry screening for the detection of critical congenital heart disease in newborn infants? ( 28081558 )
2017
41
Critical Congenital Heart Disease Newborn Screening Implementation: Lessons Learned. ( 28092064 )
2017
42
A National Call to Action-Improving the Detection of Critical Congenital Heart Disease. ( 28129863 )
2017
43
The role of palliative care in critical congenital heart disease. ( 28189331 )
2017
44
A Multicenter Initiative for Critical Congenital Heart Disease Newborn Screening in Texas Neonatal Intensive Care Units. ( 28212589 )
2017
45
Pulse oximetry is a feasible method for detecting neonatal critical congenital heart disease. ( 28235129 )
2017
46
Texas Pulse Oximetry Project: A Multicenter Educational and Quality Improvement Project for Implementation of Critical Congenital Heart Disease Screening Using Pulse Oximetry. ( 28264208 )
2017
47
Public Views on Pulse Oximetry Screening for Critical Congenital Heart Disease. ( 28329450 )
2017
48
Erratum to: Critical Congenital Heart Disease Newborn Screening Implementation: Lessons Learned. ( 28477067 )
2017
49
Retinovascular findings in newborns with critical congenital heart disease: A case series. ( 28504505 )
2017
50
Critical Congenital Heart Disease Screening in NICU: Need for Revision and Standardization. ( 28614866 )
2017

Variations for Critical Congenital Heart Disease

Expression for Critical Congenital Heart Disease

Search GEO for disease gene expression data for Critical Congenital Heart Disease.

Pathways for Critical Congenital Heart Disease

GO Terms for Critical Congenital Heart Disease

Sources for Critical Congenital Heart Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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