MCID: CRS013
MIFTS: 20

Crustacean Allergy

Categories: Immune diseases

Aliases & Classifications for Crustacean Allergy

MalaCards integrated aliases for Crustacean Allergy:

Name: Crustacean Allergy 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0060524

Summaries for Crustacean Allergy

Disease Ontology : 12 A shellfish allergy triggered by Crustacea.

MalaCards based summary : Crustacean Allergy is related to shrimp allergy and brown shrimp allergy. An important gene associated with Crustacean Allergy is TPM4 (Tropomyosin 4), and among its related pathways/superpathways are Aldosterone synthesis and secretion and Cardiac conduction. Related phenotype is Synthetic lethal with imatinib mesylate.

Related Diseases for Crustacean Allergy

Diseases related to Crustacean Allergy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 shrimp allergy 29.0 ACTB COPS7A GAPDH HLA-DQA2 LGALS3 SDF4
2 brown shrimp allergy 11.3
3 crab allergy 11.3
4 indian prawn allergy 11.3
5 tiger prawn allergy 11.3
6 white shrimp allergy 11.3
7 childhood-onset nemaline myopathy 10.3 TPM2 TPM3
8 cap myopathy 10.3 TPM2 TPM3
9 congenital structural myopathy 10.2 TPM2 TPM3
10 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 10.2 TPM2 TPM3
11 fetal adenoma 10.2 ACTB LGALS3
12 baylisascariasis 10.1 GAPDH IL4
13 mesenchymal cell neoplasm 10.0 TPM3 TPM4
14 fish allergy 9.7 LGALS3 TMEM189

Graphical network of the top 20 diseases related to Crustacean Allergy:



Diseases related to Crustacean Allergy

Symptoms & Phenotypes for Crustacean Allergy

GenomeRNAi Phenotypes related to Crustacean Allergy according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with imatinib mesylate GR00181-A 8.8 GAPDH IL4 TPM1

Drugs & Therapeutics for Crustacean Allergy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Crustacean Allergy and Dust Mites Sensitization Completed NCT01634737

Search NIH Clinical Center for Crustacean Allergy

Genetic Tests for Crustacean Allergy

Anatomical Context for Crustacean Allergy

Publications for Crustacean Allergy

Variations for Crustacean Allergy

Expression for Crustacean Allergy

Search GEO for disease gene expression data for Crustacean Allergy.

Pathways for Crustacean Allergy

GO Terms for Crustacean Allergy

Cellular components related to Crustacean Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton GO:0005856 9.85 ACTB GAPDH TPM1 TPM2 TPM3 TPM4
2 actin cytoskeleton GO:0015629 9.56 ACTB TPM1 TPM2 TPM3
3 stress fiber GO:0001725 9.33 TPM1 TPM3 TPM4
4 bleb GO:0032059 9.32 SDF4 TPM1
5 actin filament GO:0005884 9.26 TPM1 TPM2 TPM3 TPM4
6 muscle thin filament tropomyosin GO:0005862 8.92 TPM1 TPM2 TPM3 TPM4

Biological processes related to Crustacean Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 muscle contraction GO:0006936 9.46 TPM1 TPM2 TPM3 TPM4
2 positive regulation of macroautophagy GO:0016239 9.26 IL4 TBK1
3 actin filament organization GO:0007015 9.26 TPM1 TPM2 TPM3 TPM4
4 muscle filament sliding GO:0030049 8.92 TPM1 TPM2 TPM3 TPM4

Molecular functions related to Crustacean Allergy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 actin binding GO:0003779 9.56 TPM1 TPM2 TPM3 TPM4
2 actin filament binding GO:0051015 9.46 TPM1 TPM2 TPM3 TPM4
3 identical protein binding GO:0042802 9.17 ACTB GAPDH SDF4 TBK1 TPM1 TPM2
4 structural constituent of muscle GO:0008307 9.13 TPM1 TPM2 TPM4

Sources for Crustacean Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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