MCID: CRY005
MIFTS: 53

Cryptococcosis

Categories: Infectious diseases, Rare diseases, Respiratory diseases

Aliases & Classifications for Cryptococcosis

MalaCards integrated aliases for Cryptococcosis:

Name: Cryptococcosis 12 76 53 59 55 3 3 44 15
Infection by Cryptococcus Neoformans 73
Cryptococcus Neoformans Infection 12
Busse-Buschke's Disease 12
European Cryptococcosis 12
Cryptococcal Infection 12
Torulosis 12
Torula 12

Characteristics:

Orphanet epidemiological data:

59
cryptococcosis
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe); Age of onset: All ages; Age of death: any age;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:12053
ICD10 33 B45 B45.9
ICD9CM 35 117.5
MeSH 44 D003453
NCIt 50 C2967
SNOMED-CT 68 20850004 42386007
Orphanet 59 ORPHA1546
UMLS via Orphanet 74 C0010414
ICD10 via Orphanet 34 B45.1 B45.2 B45.3 more
MESH via Orphanet 45 D003453
UMLS 73 C0010414

Summaries for Cryptococcosis

CDC : 3 Cryptococcus gattii is a fungus that lives in the environment in primarily tropical and sub-tropical areas of the world but also in some temperate regions such as British Columbia and some parts of the United States. C. gattii cryptococcosis is a rare infection that people can get after breathing in the microscopic fungus. The infection can affect the lungs, central nervous system, or both.

MalaCards based summary : Cryptococcosis, also known as infection by cryptococcus neoformans, is related to cryptococcal meningitis and meningitis. An important gene associated with Cryptococcosis is SELL (Selectin L), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Amphotericin B and Miconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and skin, and related phenotypes are hematopoietic system and immune system

Disease Ontology : 12 An opportunistic mycosis that results in fungal infection and has material basis in Cryptococcus neoformans or Cryptococcus gattii.

Wikipedia : 76 Cryptococcosis, also known as cryptococcal disease, is a potentially fatal fungal disease. It is caused... more...

Related Diseases for Cryptococcosis

Diseases related to Cryptococcosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 244)
# Related Disease Score Top Affiliating Genes
1 cryptococcal meningitis 32.2 IFNG MBL2
2 meningitis 30.4 FCGR2A IFNG MBL2 TLR9
3 aspergillosis 30.1 IFNG IL4 MBL2 TLR9
4 coccidioidomycosis 30.0 CARD9 MBL2
5 candidiasis 29.9 CARD9 IFNG MBL2 PLB1
6 viral infectious disease 29.9 IFNG IL4 TLR9
7 colitis 29.8 IFNG IL4 TLR9
8 toxoplasmosis 29.8 IFNG IL4 TLR9
9 bronchiolitis 29.8 IFNG IL4 TLR9
10 central nervous system vasculitis 29.7 IFNG TLR9
11 invasive aspergillosis 29.7 IFNG MBL2 TLR9
12 pulmonary tuberculosis 29.6 IFNG IL4 MBL2 TLR9
13 lymphopenia 29.6 IFNG SELL UNC119
14 systemic lupus erythematosus 29.4 FCGR2A FCGR3A FCGR3B IFNG IL4 MBL2
15 mycobacterium tuberculosis 1 29.4 IFNG IL4 MBL2 TLR9
16 leishmaniasis 29.4 FCGR2A IFNG IL4 TLR9
17 acquired immunodeficiency syndrome 10.3
18 fixed drug eruption 10.3 IFNG SELL
19 lung cancer 10.2
20 transient neonatal neutropenia 10.2 FCGR3A FCGR3B
21 adult dermatomyositis 10.2 MBL2 TLR9
22 human immunodeficiency virus infectious disease 10.2
23 myositis fibrosa 10.2 IFNG TLR9
24 cellulitis 10.2
25 hyperlucent lung 10.2 IFNG IL4
26 adult lymphoma 10.2 FCGR2A FCGR3A
27 autoimmune myocarditis 10.2 IFNG IL4
28 kawasaki disease 10.2 FCGR2A MBL2 SELL
29 neisseria meningitidis infection 10.2 FCGR2A MBL2
30 lymphoma 10.2
31 molluscum contagiosum 10.2
32 b-cell growth factor 10.2 IFNG IL4
33 nickel allergic contact dermatitis 10.1 IFNG IL4
34 baylisascariasis 10.1 IFNG IL4
35 penicillin allergy 10.1 IFNG IL4
36 scleritis 10.1 IFNG IL4
37 atopic keratoconjunctivitis 10.1 IFNG IL4
38 crustacean allergy 10.1 IFNG IL4
39 arthritis 10.1
40 plasmodium falciparum malaria 10.1 FCGR2A IFNG TLR9
41 fungal meningitis 10.1 IFNG UNC119
42 toxic oil syndrome 10.1 IFNG IL4
43 urinary schistosomiasis 10.1 IFNG IL4
44 campylobacteriosis 10.1 IFNG ST5
45 vulvovaginal candidiasis 10.1 IL4 MBL2
46 skin conditions 10.1
47 chronic intestinal failure 10.1
48 hypersplenism 10.1 IFNG IL4
49 filarial elephantiasis 10.1 IL4 TLR9
50 hyper ige syndrome 10.1 IFNG IL4

Comorbidity relations with Cryptococcosis via Phenotypic Disease Network (PDN):


Acute Cystitis Cryptococcal Meningitis
Deficiency Anemia

Graphical network of the top 20 diseases related to Cryptococcosis:



Diseases related to Cryptococcosis

Symptoms & Phenotypes for Cryptococcosis

MGI Mouse Phenotypes related to Cryptococcosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.56 CARD9 FCGR2A FCGR3B IFNG IL4 MBL2
2 immune system MP:0005387 9.23 CARD9 FCGR2A FCGR3B IFNG IL4 MBL2

Drugs & Therapeutics for Cryptococcosis

Drugs for Cryptococcosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 85)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amphotericin B Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 1397-89-3 5280965 14956
2
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 22916-47-8 4189
3
Fluconazole Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 86386-73-4 3365
4
Voriconazole Approved, Investigational Phase 4,Phase 3 137234-62-9 71616
5
Itraconazole Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 84625-61-6 55283
6
Lamivudine Approved, Investigational Phase 4,Not Applicable 134678-17-4 60825
7
Zidovudine Approved Phase 4 30516-87-1 35370
8
Efavirenz Approved, Investigational Phase 4 154598-52-4 64139
9
Stavudine Approved, Investigational Phase 4,Not Applicable 3056-17-5 18283
10
Ritonavir Approved, Investigational Phase 4,Phase 3 155213-67-5 392622
11
Emtricitabine Approved, Investigational Phase 4 143491-57-0 60877
12
Nevirapine Approved Phase 4,Not Applicable 129618-40-2 4463
13
Tenofovir Experimental, Investigational Phase 4 147127-20-6 464205
14 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
15 Liposomal amphotericin B Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
16 Antiparasitic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
17 Antiprotozoal Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
19 Antifungal Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
20 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
21 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
22 Steroid Synthesis Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
23 Cytochrome P-450 CYP2C19 Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
24 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
26 Cytochrome P-450 CYP2C9 Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
27 Pharmaceutical Solutions Phase 4,Phase 3
28 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
29
Hydroxyitraconazole Phase 4,Phase 3,Phase 2,Not Applicable
30 Reverse Transcriptase Inhibitors Phase 4,Not Applicable
31 Anti-HIV Agents Phase 4,Phase 3,Not Applicable
32 Antiviral Agents Phase 4,Phase 3,Phase 2,Not Applicable
33 Nucleic Acid Synthesis Inhibitors Phase 4,Not Applicable
34 Anti-Retroviral Agents Phase 4,Phase 3,Not Applicable
35 Cytochrome P-450 CYP3A Inducers Phase 4,Not Applicable
36 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2
37 Atazanavir Sulfate Phase 4,Phase 3
38
protease inhibitors Phase 4,Phase 3,Phase 2
39 Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination Phase 4
40
Flucytosine Approved, Investigational Phase 2, Phase 3,Not Applicable 2022-85-7 3366
41
Posaconazole Approved, Investigational, Vet_approved Phase 3,Phase 2 171228-49-2 147912
42
Clotrimazole Approved, Vet_approved Phase 3 23593-75-1 2812
43
Aldesleukin Approved Phase 3 85898-30-2, 110942-02-4
44 tannic acid Approved Phase 3
45
Benzocaine Approved, Investigational Phase 3 94-09-7, 1994-09-7 2337
46
Sertraline Approved Phase 3 79617-96-2 68617
47 Antimetabolites Phase 2, Phase 3,Not Applicable
48 Peripheral Nervous System Agents Phase 3,Phase 2
49 Analgesics Phase 3
50 Interleukin-2 Phase 3

Interventional clinical trials:

(show top 50) (show all 64)
# Name Status NCT ID Phase Drugs
1 Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis Unknown status NCT02686853 Phase 4 Liposomal amphotericin B
2 Safety, Efficacy, and Pharmacokinetics of Amphotericin B Lipid Complex Completed NCT01656382 Phase 4 ABLC
3 Operational Research for Cryptococcal Antigen Screening Completed NCT01535469 Phase 4 Fluconazole
4 A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections Completed NCT00647907 Phase 4 Voriconazole
5 Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal Meningitis Completed NCT00976040 Phase 4
6 Efficacy of Itraconazole as Secondary Prophylaxis in Patients Undergoing Allogeneic Stem Cell Transplantation or Chemotherapy With Prior Invasive Fungal Infection Completed NCT01198236 Phase 4 Itraconazole
7 Cryptococcal Optimal ART Timing Trial Completed NCT01075152 Phase 4 efavirenz
8 Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT) Completed NCT00552240 Phase 4 tenofovir DF 300 mg QD;tenofovir DF 300 mg QD;emtricitabine 200 mg QD;emtricitabine 200 mg QD;Nevirapine 200 mg BID;Atazanavir 300 mg;Ritonavir 100 mg
9 Efficacy, Safety and Pharmacokinetics of SPK-843 in the Treatment of Pulmonary Mycosis Unknown status NCT01125644 Phase 3 SPK-843
10 Study Evaluating Efficiency and Tolerance of High-dose Fluconazole Associated With Flucytosine as Induction Therapy for Cryptococcal Meningitis Associated With HIV in Sub-saharan Africa Unknown status NCT01715922 Phase 2, Phase 3 Fluconazole;Flucytosine
11 Open Label Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P00041) Completed NCT00034658 Phase 3 Posaconazole
12 Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081) Completed NCT00000676 Phase 3 Clotrimazole;Fluconazole
13 Study of Posaconazole in the Treatment of Invasive Fungal Infections (Study P02095) Completed NCT00034632 Phase 3 Posaconazole oral suspension
14 A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection Completed NCT00784368 Phase 3 ITCZ Oral Solution;ITCZ-IV
15 Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS Completed NCT00001017 Phase 3 Fluconazole;Amphotericin B
16 PRINCE: Study of Atazanavir (ATV)/Ritonavir (RTV) Completed NCT01099579 Phase 3 Atazanavir powder;Ritonavir oral solution;Atazanavir capsules;Ritonavir capsules
17 Interleukin-2 Plus Antiretroviral Therapy for HIV-Infected Patients With Low CD4+ Counts (SILCAAT Study) Completed NCT00013611 Phase 3 Proleukin
18 An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy Completed NCT00004978 Phase 3 Recombinant interleukin-2 (rIL-2)
19 Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis Completed NCT01802385 Phase 3 Sertraline
20 Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases in Neurological Disorders in DRC Completed NCT01589289 Phase 3
21 Clinical Study of AK1820 (Isavuconazonium Sulfate) for the Treatment of Deep Mycosis Recruiting NCT03471988 Phase 3 AK1820;Voriconazole
22 Cryptococcal Antigen Screening Plus Sertraline Terminated NCT03002012 Phase 3 Sertraline;Placebo Oral Tablet;Fluconazole
23 PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893) Completed NCT00034671 Phase 2 Posaconazole oral suspension
24 High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals Completed NCT00885703 Phase 1, Phase 2 Fluconazole;Amphotericin B
25 Dexamethasone in Cryptococcal Meningitis Completed NCT00000776 Phase 2 Flucytosine;Fluconazole;Amphotericin B;Dexamethasone
26 Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis Completed NCT00145249 Phase 2 Amphotericin B;Fluconazole
27 Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis Completed NCT00012467 Phase 2 Itraconazole;Flucytosine;Fluconazole;Amphotericin B;Interferon gamma-1b
28 Treatment With Tamoxifen in Cryptococcal Meningitis Recruiting NCT03112031 Phase 2 Tamoxifen;Amphotericin B;Fluconazole
29 Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS Terminated NCT00847678 Phase 2
30 Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS Terminated NCT00324025 Phase 2 Mycograb;placebo
31 SCH 39304 as Therapy for Acute Cryptococcal Meningitis in HIV-Infected Patients Followed by Maintenance Therapy Completed NCT00000677 Phase 1 SCH 39304
32 Vietnam Cryptococcal Retention in Care Study (CRICS) Federal Financial Report Completed NCT02955862 Phase 1
33 The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis Completed NCT00002316 Phase 1 Lobradimil;Amphotericin B
34 Clinical Trial of Pulmonary Cryptococcosis in China Unknown status NCT02503449
35 Liposomal Amphotericin B for the Treatment of Cryptococcal Meningitis Unknown status NCT02136030 Not Applicable Liposomal amphotericin B;Amphotericin B-deoxycholate
36 Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans Infection Completed NCT00001701
37 Idiopathic CD4 Lymphocytopenia Completed NCT02113930
38 A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00000639 Not Applicable Itraconazole;Flucytosine;Fluconazole;Amphotericin B
39 A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients Completed NCT00002438 Not Applicable Itraconazole
40 Nevirapine Levels and Fluconazole Completed NCT00309582
41 A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS Completed NCT00002294 Not Applicable Fluconazole
42 Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00000708 Not Applicable Flucytosine;Fluconazole;Amphotericin B
43 A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis. Completed NCT00002113 Not Applicable Flucytosine;Fluconazole
44 A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B Completed NCT00002306 Not Applicable Fluconazole
45 Pilot Study of Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Completed NCT00002076 Not Applicable Fluconazole
46 Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome Completed NCT00002074 Not Applicable Fluconazole;Amphotericin B
47 Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome Completed NCT00002019 Not Applicable Amphotericin B, Lipid-based;Amphotericin B
48 A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis Completed NCT00002305 Not Applicable Flucytosine;Fluconazole;Amphotericin B
49 Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00002075 Not Applicable Flucytosine;Fluconazole;Amphotericin B
50 A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis Completed NCT00002068 Not Applicable Fluconazole;Amphotericin B

Search NIH Clinical Center for Cryptococcosis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: cryptococcosis

Genetic Tests for Cryptococcosis

Anatomical Context for Cryptococcosis

MalaCards organs/tissues related to Cryptococcosis:

41
Lung, Liver, Skin, T Cells, Heart, Bone, B Cells

Publications for Cryptococcosis

Articles related to Cryptococcosis:

(show top 50) (show all 1063)
# Title Authors Year
1
Repurposing drugs to fast-track therapeutic agents for the treatment of cryptococcosis. ( 29740519 )
2018
2
The status of cryptococcosis in Latin America. ( 29641639 )
2018
3
Diagnostic and therapeutic strategies in cryptococcosis: impact on outcome. ( 29742199 )
2018
4
Disseminated cryptococcosis in HIV negative patient. ( 29754135 )
2018
5
Additive potential of combination therapy against cryptococcosis employing a novel amphotericin B and fluconazole loaded dual delivery system. ( 29653177 )
2018
6
Outcomes of cryptococcosis in renal transplant recipients in a less-resourced health care system. ( 29677399 )
2018
7
Miliary tuberculosis with co-existing pulmonary cryptococcosis in non-HIV patient without underlying diseases: a case report. ( 29338706 )
2018
8
Tuberculous peritonitis and pleurisy accompanied by pulmonary cryptococcosis: A case report. ( 29756504 )
2018
9
Variability in innate host immune responses to cryptococcosis. ( 29668826 )
2018
10
Multifocal Soft Tissue Cryptococcosis in a Renal Transplant Recipient: The Importance of Suspecting Atypical Pathogens in the Immunocompromised Host. ( 29957160 )
2018
11
Antibody and B Cell Subset Perturbations in Human Immunodeficiency Virus-Uninfected Patients With Cryptococcosis. ( 29354657 )
2018
12
Pulmonary cryptococcosis mimicking neoplasm in terms of uptake PET/CT. ( 29540949 )
2018
13
Neglected disease, neglected populations: the fight against Cryptococcus and cryptococcosis. ( 29668824 )
2018
14
Disseminated cryptococcosis presenting initially as lower limb cellulitis in a renal transplant recipient - a case report. ( 29374464 )
2018
15
Isolated iliac cryptococcosis in an immunocompetent patient. ( 29596420 )
2018
16
Treatment of cryptococcosis in non-HIV immunocompromised patients. ( 29738314 )
2018
17
Cutaneous cryptococcosis. ( 29735406 )
2018
18
Cryptococcosis with bird's eye manifestation: A case report. ( 29697086 )
2018
19
Diminished CD40L expression on T-cells in a case of disseminated cryptococcosis. ( 29567905 )
2018
20
Clinical features and radiological characteristics of pulmonary cryptococcosis. ( 29848126 )
2018
21
Epidemiological trends of cryptococcosis in Italy: Molecular typing and susceptibility pattern of Cryptococcus neoformans isolates collected during a 20-year period. ( 29373716 )
2018
22
Ulcerative cellulitis of the arm: a case of primary cutaneous cryptococcosis. ( 29630156 )
2018
23
Duodenum Cryptococcosis Mimicking Primary Duodenum Cancer on PET/CT Imaging. ( 29538024 )
2018
24
Cryptococcosis as a cause of nephrotic syndrome? A case report and review of the literature. ( 29942774 )
2018
25
Cutaneous Cryptococcosis Mimicking Leishmaniasis. ( 29342402 )
2018
26
Disseminated cryptococcosis associated with administration of eculizumab. ( 29895518 )
2018
27
Pulmonary cryptococcosis coexisting with adenocarcinoma: a case report and review of the literature. ( 30384858 )
2018
28
Disseminated Cryptococcosis with Bronchiolitis and Cellulitis. ( 30179584 )
2018
29
A phenylthiazole derivative demonstrates efficacy on treatment of the cryptococcosis & candidiasis in animal models. ( 30057783 )
2018
30
Central Nervous System Vasculitis for Cryptococcosis in an Immunocompetent Patient. ( 30200288 )
2018
31
Disseminated cryptococcosis in Crohn's disease: a case report. ( 30514241 )
2018
32
Examination of cryptococcal glucuronoxylomannan antigen in bronchoalveolar lavage fluid for diagnosing pulmonary cryptococcosis in HIV-negative patients. ( 28419364 )
2018
33
Systemic cryptococcosis in an immune-competent child. ( 28965793 )
2018
34
Epidemiology and trends of cryptococcosis in the United States from 2000 to 2007: A population-based study. ( 28971712 )
2018
35
A new method for studying cryptococcosis in a murine model using 99mTc-Cryptococcus gattii. ( 28992125 )
2018
36
Disseminated cryptococcosis in a patient taking tocilizumab for Castleman's disease. ( 29021093 )
2018
37
Disseminated Cryptococcosis with Marked Eosinophilia in a Postpartum Woman. ( 29021482 )
2018
38
Comparative Epidemiology and Outcomes of Human Immunodeficiency virus (HIV), Non-HIV Non-transplant, and Solid Organ Transplant Associated Cryptococcosis: A Population-Based Study. ( 29028978 )
2018
39
Pulmonary cryptococcosis diagnosed on a lung fine-needle aspiration. ( 29063707 )
2018
40
Potassium iodide: A forgotten remedy for cutaneous cryptococcosis. ( 29124847 )
2018
41
Cryptococcosis in an Infectious Diseases Hospital of Buenos Aires, Argentina. Revision of 2041 cases: Diagnosis, clinical features and therapeutics. ( 29129578 )
2018
42
Fluconazole levels in serum and cerebrospinal fluid according to daily dosage in patients with cryptococcosis and other fungal infections. ( 29144957 )
2018
43
Cryptococcosis manifesting as isolated biliary infection: Case report and brief review of literature. ( 29150356 )
2018
44
Kinsbourne syndrome associated with cryptococcosis infection. ( 29174170 )
2018
45
Disseminated Cryptococcosis Presenting as Miliary Lung Shadows in an Immunocompetent Child. ( 29177510 )
2018
46
Brainstem dysfunction heralding disseminated cryptococcosis. ( 29454181 )
2018
47
Antifungal activity of Annona coriacea Mart. ethanol extracts against the aetiological agents of cryptococcosis. ( 29463129 )
2018
48
Cryptococcosis in Colombia: Compilation and Analysis of Data from Laboratory-Based Surveillance. ( 29494502 )
2018
49
The war on cryptococcosis: A Review of the antifungal arsenal. ( 29513785 )
2018
50
Pyoderma gangrenosum and primary cutaneous cryptococcosis in an ulcerative colitis patient. ( 29519678 )
2018

Variations for Cryptococcosis

Expression for Cryptococcosis

Search GEO for disease gene expression data for Cryptococcosis.

Pathways for Cryptococcosis

Pathways related to Cryptococcosis according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.78 CARD9 FCGR2A FCGR3A FCGR3B IFNG IL4
2 12.33 CARD9 IFNG IL4 TLR9
3
Show member pathways
12.27 FCGR3A FCGR3B IFNG IL4
4
Show member pathways
11.99 FCGR2A FCGR3A FCGR3B IFNG IL4
5
Show member pathways
11.94 IFNG IL4 TLR9
6 11.92 FCGR2A FCGR3A FCGR3B MBL2
7 11.81 FCGR2A FCGR3A FCGR3B IFNG
8 11.78 FCGR2A IFNG IL4
9 11.73 FCGR2A IFNG IL4 SELL
10 11.69 CARD9 FCGR2A FCGR3A FCGR3B IFNG TLR9
11
Show member pathways
11.65 FCGR2A FCGR3A FCGR3B IFNG IL4
12 11.58 FCGR2A FCGR3B TLR9
13 11.5 IFNG SELL TLR9
14 11.31 FCGR2A FCGR3A FCGR3B MBL2
15 11.1 IFNG IL4
16 11.08 IFNG IL4
17 11.03 IFNG IL4
18 10.97 IFNG IL4
19 10.87 FCGR2A FCGR3A FCGR3B IFNG IL4

GO Terms for Cryptococcosis

Cellular components related to Cryptococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule membrane GO:0030667 8.8 FCGR2A FCGR3B SELL

Biological processes related to Cryptococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to virus GO:0051607 9.33 CARD9 IFNG TLR9
2 immune response GO:0006955 9.02 FCGR3A FCGR3B IFNG IL4 TLR9
3 positive regulation of interleukin-12 production GO:0032735 8.96 IFNG TLR9

Molecular functions related to Cryptococcosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 IgG binding GO:0019864 8.8 FCGR2A FCGR3A FCGR3B

Sources for Cryptococcosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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