MCID: CRY003
MIFTS: 52

Cryptosporidiosis

Categories: Gastrointestinal diseases, Immune diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Cryptosporidiosis

MalaCards integrated aliases for Cryptosporidiosis:

Name: Cryptosporidiosis 12 77 54 60 56 44 3 45 15 74
Cryptosporidial Gastroenteritis 12 74
Infection by Cryptosporidium 12
Intestinal Cryptosporidiosis 12

Characteristics:

Orphanet epidemiological data:

60
cryptosporidiosis
Inheritance: Not applicable; Prevalence: 1-9/100000 (United States),1-9/100000 (Europe); Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 60  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:1733
ICD9CM 36 007.4
MeSH 45 D003457
NCIt 51 C128408
SNOMED-CT 69 58777003
ICD10 34 A07.2
MESH via Orphanet 46 D003457
ICD10 via Orphanet 35 A07.2
UMLS via Orphanet 75 C0010418
Orphanet 60 ORPHA1549

Summaries for Cryptosporidiosis

MedlinePlus : 44 Cryptosporidiosis (crypto) is an illness caused by a parasite. The parasite lives in soil, food, and water. It may also be on surfaces that have been contaminated with feces (poop). You can become infected by swallowing the parasite, if it is in your food, drinking water, or water that you swim in. You can also get it by touching your mouth with contaminated hands. The most common symptom of crypto is watery diarrhea. Other symptoms include Dehydration Weight loss Stomach cramps or pain Fever Nausea Vomiting Contact your health care provider if you have watery diarrhea that lasts more than a few days. Most people with crypto get better without treatment within one to two weeks. But crypto can cause serious problems in people with weak immune systems, like those with HIV/AIDS. To reduce your risk of crypto, wash your hands often, only drink water that you know is safe, and wash or peel fresh fruits and vegetables before eating. Centers for Disease Control and Prevention

MalaCards based summary : Cryptosporidiosis, also known as cryptosporidial gastroenteritis, is related to giardiasis and toxoplasmosis, and has symptoms including fever and pruritus. An important gene associated with Cryptosporidiosis is SST (Somatostatin), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Primary immunodeficiency. The drugs Anti-Infective Agents and Anti-Retroviral Agents have been mentioned in the context of this disorder. Affiliated tissues include small intestine, lung and breast, and related phenotypes are homeostasis/metabolism and immune system

Disease Ontology : 12 A coccidiosis that involves a parasitic protozoan infection of the intestine of humans and a wide range of animals caused by Cryptosporidium species, through contaminated water and food, The symptoms include watery diarrhea, dehydration, weight loss, abdominal pain, fever, nausea and vomiting. Cryptosporidium infections have also been found in other digestive tract organs, the lungs, and conjunctiva. Immunocompromised persons are at greater risk of developing the infection.

NIH Rare Diseases : 54 Cryptosporidiosis is an illness caused by the parasite, Cryptosporidium. The condition is most commonly associated with watery diarrhea. Other signs and symptoms may include dehydration, weight loss, stomach cramps, fever, nausea and/or vomiting. Cryptosporidiosis occurs when the parasite enters the body, often through contaminated food and water or because of poor handwashing hygiene. Although cryptosporidiosis can affect all people, young children, pregnant women and people with severely weakened immune systems (i.e. those with AIDS; cancer and transplant patients who are taking certain immunosuppressive drugs; and those with inherited diseases that affect the immune system) are likely to develop a more serious illness. Medications such as nitazoxanide have been used to treat diarrhea in both adults and children. However, most people who have healthy immune systems will recover without treatment.

CDC : 3 Cryptosporidium is a microscopic parasite that causes the diarrheal disease cryptosporidiosis. Both the parasite and the disease are commonly known as “Crypto.”

Wikipedia : 77 Cryptosporidiosis, also known as crypto, is a parasitic disease caused by Cryptosporidium, a genus of... more...

Related Diseases for Cryptosporidiosis

Diseases related to Cryptosporidiosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 146)
# Related Disease Score Top Affiliating Genes
1 giardiasis 30.6 CD79A TPI1
2 toxoplasmosis 30.2 CD40LG CD79A DHFR
3 coccidiosis 30.1 BFSP2 SLC15A1
4 immunoglobulin alpha deficiency 30.0 CD40LG CD79A
5 strongyloidiasis 30.0 CCL11 CD79A
6 pneumocystosis 29.9 CD40LG DHFR
7 malaria 29.5 CCL11 CD40LG CXCL10 DHFR IL1A
8 cryptorchidism, unilateral or bilateral 11.2
9 diarrhea 10.6
10 acquired immunodeficiency syndrome 10.5
11 wdha syndrome 10.4 SST VIP
12 postgastrectomy syndrome 10.4 SST VIP
13 glucagonoma 10.4 SST VIP
14 vipoma 10.4 SST VIP
15 acrodermatitis chronica atrophicans 10.4 CD40LG CXCL10
16 pancreatic cholera 10.4 SST VIP
17 anismus 10.4 TAC1 VIP
18 somatostatinoma 10.4 SST VIP
19 binswanger's disease 10.3 SST VIP
20 congenital rubella 10.3 CAT CD40LG
21 human immunodeficiency virus infectious disease 10.3
22 gastrinoma 10.3 SST VIP
23 c1q nephropathy 10.3 CD40LG CD79A
24 diffuse pulmonary fibrosis 10.3 TAC1 VIP
25 immunoglobulin g deficiency 10.3 CD40LG CD79A
26 cryofibrinogenemia 10.3 CD40LG CD79A
27 scabies 10.3 CCL11 IL1A
28 heparin-induced thrombocytopenia 10.3 CD40LG CD79A
29 immunoglobulin a deficiency 1 10.3 CD40LG CD79A
30 sporotrichosis 10.3 CD40LG CD79A
31 congenital syphilis 10.3 CD40LG CD79A
32 syphilis 10.3 CD40LG CD79A
33 secondary syphilis 10.3 CD40LG CD79A
34 japanese spotted fever 10.3 CCL11 CXCL10
35 immunodeficiency-centromeric instability-facial anomalies syndrome 1 10.3 CD40LG CD79A
36 breast abscess 10.3 CAT CD40LG
37 ocular toxoplasmosis 10.3 CD40LG CD79A
38 persistent generalized lymphadenopathy 10.3 CD40LG CD79A
39 keratopathy 10.3 IL1A TAC1
40 immunodeficiency with hyper-igm, type 1 10.3 CD40LG CD79A
41 congenital hypogammaglobulinemia 10.3 CD79A IL1A
42 congenital toxoplasmosis 10.2 CD40LG CD79A
43 radiculopathy 10.2 CCL11 IL1A
44 chronic graft versus host disease 10.2 CD79A IL1A
45 vasomotor rhinitis 10.2 CD40LG TAC1 VIP
46 lymphoproliferative syndrome 2 10.2 CD40LG CXCL10
47 carrion's disease 10.2 CCL11 CXCL10
48 microsporidiosis 10.2
49 islet cell tumor 10.2 SST VIP
50 constipation 10.2 SST TAC1 VIP

Graphical network of the top 20 diseases related to Cryptosporidiosis:



Diseases related to Cryptosporidiosis

Symptoms & Phenotypes for Cryptosporidiosis

UMLS symptoms related to Cryptosporidiosis:


fever, pruritus

MGI Mouse Phenotypes related to Cryptosporidiosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 CAT CD40LG CD79A CXCL10 DHFR IL1A
2 immune system MP:0005387 9.28 CCL11 CD40LG CD79A CXCL10 DHFR IL1A

Drugs & Therapeutics for Cryptosporidiosis

Drugs for Cryptosporidiosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 62)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
2 Anti-Retroviral Agents Phase 4,Phase 3
3 Antiviral Agents Phase 4,Phase 3
4
Nitazoxanide Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 55981-09-4 41684
5
Rifabutin Approved, Investigational Phase 3 72559-06-9 46783538 6323490
6
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2 22916-47-8 4189
7
Azithromycin Approved Phase 3,Phase 1,Phase 2,Not Applicable 83905-01-5 447043 55185
8
Fluconazole Approved, Investigational Phase 3,Phase 2 86386-73-4 3365
9
Ritonavir Approved, Investigational Phase 3 155213-67-5 392622
10
Sertraline Approved Phase 3 79617-96-2 68617
11 Antiparasitic Agents Phase 3,Phase 2,Phase 1,Not Applicable
12 Cytochrome P-450 Enzyme Inhibitors Phase 3,Phase 2
13 Antitubercular Agents Phase 3
14 Steroid Synthesis Inhibitors Phase 3,Phase 2
15 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
16 Hormone Antagonists Phase 3,Phase 2
17 Antibiotics, Antitubercular Phase 3
18 Cytochrome P-450 CYP2C19 Inhibitors Phase 3,Phase 2
19 Hormones Phase 3,Phase 2
20 Cytochrome P-450 CYP2C9 Inhibitors Phase 3,Phase 2
21 Antifungal Agents Phase 3,Phase 2
22 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1,Not Applicable
23
protease inhibitors Phase 3
24 Atazanavir Sulfate Phase 3
25 HIV Protease Inhibitors Phase 3
26 Pharmaceutical Solutions Phase 3
27 Anti-HIV Agents Phase 3
28 Cytochrome P-450 CYP3A Inhibitors Phase 3
29 Antiprotozoal Agents Phase 3,Phase 2,Phase 1,Not Applicable
30 Antidepressive Agents Phase 3
31 Serotonin Uptake Inhibitors Phase 3
32 Neurotransmitter Agents Phase 3
33 Serotonin Agents Phase 3
34 Psychotropic Drugs Phase 3
35 Neurotransmitter Uptake Inhibitors Phase 3
36
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
37
Paromomycin Approved, Investigational Phase 2,Phase 1,Not Applicable 7542-37-2, 1263-89-4 165580
38
Clofazimine Approved, Investigational Phase 2 2030-63-9 2794
39
Flucytosine Approved, Investigational Phase 2 2022-85-7 3366
40 Immunologic Factors Phase 1, Phase 2,Not Applicable
41 Anti-Inflammatory Agents Phase 2
42 Interleukin-12 Phase 1, Phase 2,Not Applicable
43 Angiogenesis Modulating Agents Phase 1, Phase 2,Not Applicable
44 Adjuvants, Immunologic Phase 1, Phase 2,Not Applicable
45 Angiogenesis Inhibitors Phase 1, Phase 2,Not Applicable
46 Antimetabolites Phase 2
47
Loperamide Approved Phase 1,Not Applicable 53179-11-6 3955
48
Spiramycin Approved Phase 1,Not Applicable 24916-50-5
49 Antidiarrheals Phase 1,Not Applicable
50 Antibodies Phase 1,Not Applicable

Interventional clinical trials:

(show all 33)
# Name Status NCT ID Phase Drugs
1 Optimal Time to Start Antiretroviral Therapy in HIV-infected Adults With Cryptococcal Meningitis Completed NCT00976040 Phase 4
2 A Randomized Study of Daily and Intermittent Prophylactic Regimens for the Prevention of Disseminated Mycobacterium Avium Complex (MAC) and Fungal Infections in HIV-Infected Patients Completed NCT00002122 Phase 3 Azithromycin;Rifabutin;Fluconazole
3 PRINCE: Study of Atazanavir (ATV)/Ritonavir (RTV) Completed NCT01099579 Phase 3 Atazanavir powder;Ritonavir oral solution;Atazanavir capsules;Ritonavir capsules
4 Safety and Effectiveness of Nitazoxanide for the Treatment of Cryptosporidiosis in AIDS Patients Terminated NCT00004986 Phase 3 Nitazoxanide
5 Cryptococcal Antigen Screening Plus Sertraline Terminated NCT03002012 Phase 3 Sertraline;Placebo Oral Tablet;Fluconazole
6 A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3 Completed NCT00000771 Phase 2 Paromomycin sulfate
7 A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by Cryptosporidium Completed NCT00001081 Phase 2 Nitazoxanide
8 Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected Children Completed NCT00055107 Phase 1, Phase 2 Nitazoxanide
9 A Phase 2A Evaluation of the Safety, Tolerability, Pharmacokinetics, Efficacy of Clofazimine (CFZ) in Cryptosporidiosis Recruiting NCT03341767 Phase 2 Clofazimine;Placebo
10 Interleukin 12 (IL-12) for the Treatment of Cryptosporidiosis in AIDS Patients Terminated NCT00057486 Phase 1, Phase 2 IL-12
11 Safety Study of Fluconazole in Combination With Flucytosine for the Treatment of Early Cryptococcal Infection Terminated NCT01562132 Phase 2 Flucytosine and fluconazole;Fluconazole
12 A Study of Letrazuril in the Treatment of AIDS-Related Diarrhea Completed NCT00001018 Phase 1 Letrazuril
13 A Randomized, Multicenter, Double-Blind, Parallel-Group, Placebo-Controlled Trial of the Efficacy and Safety of Bovine Anti-Cryptosporidium Immunoglobulin (BACI) in the Treatment of Cryptosporidium Enteritis in AIDS Patients Completed NCT00002248 Phase 1 Cryptosporidium Immune Whey Protein Concentrate (Bovine)
14 A Study of Spiramycin in the Treatment of Patients With AIDS-Related Diarrhea Completed NCT00000980 Phase 1 Spiramycin
15 A Study of Nitazoxanide in the Treatment of AIDS-Related Diarrhea Completed NCT00002444 Phase 1 Nitazoxanide
16 A Study to Evaluate the Use of Nitazoxanide to Treat Cryptosporidiosis Unknown status NCT00002158 Not Applicable Nitazoxanide
17 Transmission and the Respiratory Tract in Cryptosporidiosis Completed NCT00507871
18 Azithromycin in the Treatment of Cryptosporidiosis in Patients Who Have Not Had Success With Other Drugs Completed NCT00002328 Not Applicable Azithromycin
19 Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study Completed NCT00002082 Not Applicable Azithromycin
20 Protocol For the Treatment of Cryptosporidiosis in AIDS Patients With Diclazuril (R64,433) Completed NCT00002027 Not Applicable Diclazuril
21 A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS Completed NCT00002278 Not Applicable Diclazuril
22 Open-Label "Compassionate" Use Study of Spiramycin for the Treatment of Diarrhea Due to Chronic Cryptosporidiosis in Immunocompromised Patients Completed NCT00002062 Not Applicable Spiramycin
23 The Effectiveness of Cow's Milk Immune Globulin in the Treatment of AIDS-Related Diarrhea Completed NCT00002264 Not Applicable Cryptosporidium Immune Whey Protein Concentrate (Bovine)
24 Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya Completed NCT01695304 Not Applicable
25 Field Studies of Amebiasis in Bangladesh Completed NCT02734264
26 Breast Milk Composition and HIV-exposed/Unexposed Early Infant Growth and Infectious Disease Events Completed NCT01699841
27 Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders Completed NCT02105714
28 HIV Cohort Study At Johns Hopkins University, University of North Carolina at Chapel Hill and Vanderbilt University Completed NCT01339416
29 Kaiser Permanente HIV Cohort Study Completed NCT01339403
30 Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in Poland Recruiting NCT03490435
31 Cryptosporidiosis and Enteropathogens in Bangladesh Active, not recruiting NCT02764918
32 Treatment of Chronic Cryptosporidiosis in AIDS Patients Terminated NCT00001128 Not Applicable Interleukin-12;Paromomycin sulfate;Azithromycin
33 Parasitic Infections of the Gastrointestinal Tract Terminated NCT00001162

Search NIH Clinical Center for Cryptosporidiosis

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Cochrane evidence based reviews: cryptosporidiosis

Genetic Tests for Cryptosporidiosis

Anatomical Context for Cryptosporidiosis

MalaCards organs/tissues related to Cryptosporidiosis:

42
Small Intestine, Lung, Breast, Liver, T Cells, Testes, B Cells

Publications for Cryptosporidiosis

Articles related to Cryptosporidiosis:

(show top 50) (show all 1401)
# Title Authors Year
1
Risk Factors for Sporadic Cryptosporidiosis in the Netherlands: Analysis of a 3-Year Population Based Case-Control Study Coupled With Genotyping, 2013-2016. ( 30395258 )
2019
2
Case Report: Diagnosis of Cryptosporidiosis in Renal Transplantation in a Low-Prevalence Setting. ( 30457100 )
2019
3
Development of 5-aminopyrazole-4-carboxamide-based bumped-kinase inhibitors for Cryptosporidiosis therapy. ( 30830766 )
2019
4
Cryptosporidiosis Outbreak Investigation in a Canadian Correctional Facility Using Novel Case Finding Tools. ( 30866705 )
2019
5
Analysis of the Cryptosporidium spp. and gp60 subtypes linked to human outbreaks of cryptosporidiosis in England and Wales, 2009 to 2017. ( 30867023 )
2019
6
An apple a day: an outbreak of cryptosporidiosis in Norway associated with self-pressed apple juice. ( 30869057 )
2019
7
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. ( 30894487 )
2019
8
Case-case analyses of cryptosporidiosis and giardiasis using routine national surveillance data in the United States - 2005-2015. ( 31063098 )
2019
9
Outbreak of cryptosporidiosis due to Cryptosporidium parvum subtype IIdA19G1 in neonatal calves on a dairy farm in China. ( 31071320 )
2019
10
Long-term use of yeast fermentation products in comparison to halofuginone for the control of cryptosporidiosis in neonatal calves. ( 31079829 )
2019
11
The piglet acute diarrhea model for evaluating efficacy of treatment and control of cryptosporidiosis. ( 30036127 )
2018
12
Cryptosporidiosis Outbreak in Immunocompetent Children from a Remote Area of French Guiana. ( 29692312 )
2018
13
Impact of confinement housing on study end-points in the calf model of cryptosporidiosis. ( 29694356 )
2018
14
Assessing the impact of environmental exposures and Cryptosporidium infection in cattle on human incidence of cryptosporidiosis in Southwestern Ontario, Canada. ( 29698463 )
2018
15
Epidemiology and Risk Factors for Cryptosporidiosis in Children From 8 Low-income Sites: Results From the MAL-ED Study. ( 29701852 )
2018
16
Cryptosporidiosis in a fire skink (Lepidothyris fernandi) and molecular identification of infecting species ( 29717577 )
2018
17
Giardia/Cryptosporidium QUIK CHEK Assay Is More Specific Than Quantitative Polymerase Chain Reaction for Rapid Point-of-care Diagnosis of Cryptosporidiosis in Infants in Bangladesh. ( 29718129 )
2018
18
Long-term sequelae of sporadic cryptosporidiosis: a follow-up study. ( 29730717 )
2018
19
Cryptosporidiosis: A zoonotic disease concern. ( 29915508 )
2018
20
Laboratory diagnosis of cryptosporidiosis. ( 29930899 )
2018
21
Comparison of three cryptosporidiosis outbreaks in Western Australia: 2003, 2007 and 2011. ( 29974834 )
2018
22
Novel treatment strategies and drugs in development for cryptosporidiosis. ( 30003818 )
2018
23
Sheep as a Potential Source of Zoonotic Cryptosporidiosis in China. ( 30006394 )
2018
24
Intestinal cryptosporidiosis in renal transplant recipients: Prevalence, species detection and comparative evaluation of SSU rRNA and Cryptosporidium oocyst wall protein genes. ( 30084419 )
2018
25
Human cryptosporidiosis in immunodeficient patients in France (2015-2017). ( 30107154 )
2018
26
Rapid diagnostic tests relying on antigen detection from stool as an efficient point of care testing strategy for giardiasis and cryptosporidiosis? Evaluation of a new immunochromatographic duplex assay. ( 30122511 )
2018
27
Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial. ( 30139372 )
2018
28
Limitations in the screening of potentially anti-cryptosporidial agents using laboratory rodents with gastric cryptosporidiosis. ( 30152784 )
2018
29
Probiotic Product Enhances Susceptibility of Mice to Cryptosporidiosis. ( 30171003 )
2018
30
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. ( 30282735 )
2018
31
Amixicile Reduces Severity of Cryptosporidiosis but Does Not Have In Vitro Activity against Cryptosporidium. ( 30297368 )
2018
32
Socio-Behavioral Risk Factors Associated with Cryptosporidiosis in HIV/AIDS Patients Visiting the HIV Referral Clinic at Cape Coast Teaching Hospital, Ghana. ( 30369995 )
2018
33
A spatial analysis of giardiasis and cryptosporidiosis in relation to public water supply distribution in North West England. ( 30409377 )
2018
34
Disinfection with hydrated lime may help manage cryptosporidiosis in calves. ( 30503093 )
2018
35
Identification of novel vaccine candidates against cryptosporidiosis of neonatal bovines by reverse vaccinology. ( 30503096 )
2018
36
Beyond reasonable drought: hotspots reveal a link between the 'Big Dry' and cryptosporidiosis in Australia's Murray Darling Basin. ( 30540277 )
2018
37
Imported cryptosporidiosis caused by Cryptosporidium hominis IbA13G3 in Spain. The relevance of molecular-based surveillance. ( 30583883 )
2018
38
Two outbreaks of cryptosporidiosis associated with cattle spring pasture events. ( 31014741 )
2018
39
Evaluation of enzyme linked immunosorbent assay for stool antigen detection for the diagnosis of cryptosporidiosis among HIV negative immunocompromised patients in a tertiary care hospital of northern India. ( 28668658 )
2018
40
Clinical Manifestations of Cryptosporidiosis and Identification of a New Cryptosporidium Subtype in Patients From Sonora, Mexico. ( 28858043 )
2018
41
Foodborne cryptosporidiosis. ( 29122606 )
2018
42
Cryptosporidiosis in a transplant recipient with severe intractable diarrhea: Detection of Cryptosporidium oocysts by intestinal biopsies. ( 29277954 )
2018
43
The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases. ( 29300993 )
2018
44
Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model. ( 29309415 )
2018
45
A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open-Access Malaria Box. ( 29339392 )
2018
46
Treatment of cryptosporidiosis in captive green iguanas (Iguana iguana). ( 29559143 )
2018
47
Epidemiological observations on cryptosporidiosis and molecular characterization of Cryptosporidium spp. in sheep and goats in Kuwait. ( 29594423 )
2018
48
A Randomized Controlled Trial to Assess the Impact of Ceramic Water Filters on Prevention of Diarrhea and Cryptosporidiosis in Infants and Young Children-Western Kenya, 2013. ( 29611500 )
2018
49
Occupational Animal Exposure Among Persons with Campylobacteriosis and Cryptosporidiosis - Nebraska, 2005-2015. ( 28910275 )
2017
50
Gastric Intussusceptions in a Red Corn Snake (Pantherophis guttatus) Associated with Cryptosporidiosis. ( 29955428 )
2017

Variations for Cryptosporidiosis

Expression for Cryptosporidiosis

Search GEO for disease gene expression data for Cryptosporidiosis.

Pathways for Cryptosporidiosis

Pathways related to Cryptosporidiosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.34 IL1A SST TAC1
2 10.89 CD40LG CD79A
3 10.79 CCL11 CXCL10
4 10.36 CCL11 CD40LG CXCL10 IL1A
5 10.15 CCL11 CD40LG CXCL10 IL1A

GO Terms for Cryptosporidiosis

Cellular components related to Cryptosporidiosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 CAT CCL11 CD40LG CXCL10 IL1A SST
2 extracellular space GO:0005615 9.23 CAT CCL11 CD40LG CXCL10 IL1A SST

Biological processes related to Cryptosporidiosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor signaling pathway GO:0007186 9.77 CCL11 CXCL10 SST TAC1 VIP
2 cell-cell signaling GO:0007267 9.58 CXCL10 SST TAC1
3 immune response GO:0006955 9.46 CCL11 CD40LG CXCL10 IL1A
4 inflammatory response GO:0006954 9.35 CCL11 CD40LG CXCL10 IL1A TAC1
5 response to radiation GO:0009314 9.32 CAT CCL11
6 B cell proliferation GO:0042100 9.26 CD40LG CD79A
7 regulation of signaling receptor activity GO:0010469 9.1 CCL11 CD40LG CXCL10 IL1A SST VIP

Molecular functions related to Cryptosporidiosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 NADP binding GO:0050661 8.96 CAT DHFR
2 cytokine activity GO:0005125 8.92 CCL11 CD40LG CXCL10 IL1A

Sources for Cryptosporidiosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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