MCID: CRY024
MIFTS: 21

Crystal Arthropathies

Categories: Bone diseases, Rare diseases

Aliases & Classifications for Crystal Arthropathies

MalaCards integrated aliases for Crystal Arthropathies:

Name: Crystal Arthropathies 52
Crystal Arthropathy 71

Classifications:



External Ids:

ICD10 32 M11.8 M11.9
UMLS 71 C0152087

Summaries for Crystal Arthropathies

NIH Rare Diseases : 52 Crystal arthropathies are a diverse group of bone diseases associated with the deposition of minerals within joints and the soft tissues around the joints. The group includes gout , basic calcium phosphate and calcium pyrophosphate dihydrate deposition diseases , and, in very rare cases, calcium oxalate crystal arthropathy which is a rare cause of arthritis characterized by deposition of calcium oxalate crystals within synovial fluid and typically occurs in patients with underlying primary or secondary hyperoxaluria . These crystals are responsible for different rheumatic syndromes , including acute or chronic synovial inflammation and cartilage degeneration. Treatment depends on the specific condition.

MalaCards based summary : Crystal Arthropathies, also known as crystal arthropathy, is related to tumoral calcinosis, hyperphosphatemic, familial, 1 and arthropathy, and has symptoms including arthralgia and metatarsalgia. The drugs Antirheumatic Agents and Interleukin 1 Receptor Antagonist Protein have been mentioned in the context of this disorder. Affiliated tissues include bone, kidney and skin.

Wikipedia : 74 Crystal arthropathy is a class of joint disorder (called arthropathy) that is characterized by... more...

Related Diseases for Crystal Arthropathies

Diseases related to Crystal Arthropathies via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 23)
# Related Disease Score Top Affiliating Genes
1 tumoral calcinosis, hyperphosphatemic, familial, 1 10.6
2 arthropathy 10.5
3 gout 10.5
4 tumoral calcinosis, normophosphatemic, familial 10.5
5 familial tumoral calcinosis 10.5
6 familial calcium pyrophosphate deposition 10.5
7 chondrocalcinosis 10.3
8 hyperuricemia 10.1
9 synovitis 10.1
10 spinal stenosis 10.0
11 osteoarthritis 10.0
12 spondylolisthesis 9.8
13 myeloma, multiple 9.8
14 cauda equina syndrome 9.8
15 hyperparathyroidism 9.8
16 frozen shoulder 9.8
17 adult-onset still's disease 9.8
18 hypothyroidism 9.8
19 rheumatic disease 9.8
20 bursitis 9.8
21 lipid metabolism disorder 9.8
22 septic arthritis 9.8
23 arthritis 9.8

Graphical network of the top 20 diseases related to Crystal Arthropathies:



Diseases related to Crystal Arthropathies

Symptoms & Phenotypes for Crystal Arthropathies

UMLS symptoms related to Crystal Arthropathies:


arthralgia, metatarsalgia

Drugs & Therapeutics for Crystal Arthropathies

Drugs for Crystal Arthropathies (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antirheumatic Agents Phase 2
2 Interleukin 1 Receptor Antagonist Protein Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment of Refractory Hemochromatosis Rheumatism by Anakinra: a Preliminary Phase II Study Terminated NCT02263638 Phase 2 Anakinra
2 A Structured Nurse Led Patient Management Programme to Improve Outcomes in Gout: A Randomized Controlled Trial Recruiting NCT03345186

Search NIH Clinical Center for Crystal Arthropathies

Genetic Tests for Crystal Arthropathies

Anatomical Context for Crystal Arthropathies

MalaCards organs/tissues related to Crystal Arthropathies:

40
Bone, Kidney, Skin, Testes, Neutrophil

Publications for Crystal Arthropathies

Articles related to Crystal Arthropathies:

(show top 50) (show all 137)
# Title Authors PMID Year
1
Prevalence and incidence of non-gout crystal arthropathy in southern Sweden. 61
31847885 2019
2
Pseudogout or pseudolymphoma? Calcium pyrophosphate deposition disease of the cervical spine: a rare presentation and literature review. 61
31796457 2019
3
Dual-energy CT in the differentiation of crystal depositions of the wrist: does it have added value? 61
31802167 2019
4
Acute kidney injury associated with febuxostat and allopurinol: a post-marketing study. 61
31703711 2019
5
Mixed crystal arthropathy of the wrist: The contribution of imaging in the diagnostic approach. 61
29183711 2019
6
Updating the use of the Madrid Sonographic Enthesis Index (MASEI): a systematic review of the literature. 61
31750519 2019
7
[Crystal arthropathies]. 61
31350748 2019
8
Clinical Utility of Multi-Energy Spectral Photon-Counting Computed Tomography in Crystal Arthritis. 61
30714678 2019
9
Elevated Procalcitonin in Acute Pseudogout Flare: A Case Report. 61
31410336 2019
10
Subgroups of patients with osteoarthritis and medial meniscus tear or crystal arthropathy benefit from arthroscopic treatment. 61
30128683 2019
11
Can C-Reactive Protein Be Used to Predict Acute Septic Arthritis in the Adult Population? 61
30708377 2019
12
Subclinical crystal arthropathy: a silent contributor to inflammation and functional disability in knees with osteoarthritis-an ultrasound study. 61
30327988 2019
13
A rare cause of back pain and radiculopathy - spinal tophi: a case report. 61
30626451 2019
14
Acute arthritis: predictive factors and current practice in the approach to diagnosis and management across two hospitals in Sydney. 61
29756282 2018
15
[Haemochromatosis and Arthropathies]. 61
30086562 2018
16
[Update on Gout and Calcium pyrophosphate deposition (CPPD)]. 61
30086561 2018
17
First Presentation of Acute Pseudogout Following Total Knee Replacement. 61
30687658 2018
18
Inflammatory arthritis and crystal arthropathy: Current concepts of skin and systemic manifestations. 61
30047436 2018
19
Socio-economic inequalities in occurrence and health care costs in rheumatic and musculoskeletal diseases: results from a Spanish population-based study including 1.9 million persons. 61
29465359 2018
20
Advanced Imaging in the Diagnosis of Gout and Other Crystal Arthropathies. 61
29672810 2018
21
Systematic Overview of Solid Particles and Their Host Responses. 61
29892295 2018
22
Knee joint synovitis: study of correlations and diagnostic performances of ultrasonography compared with histopathology. 61
29531789 2018
23
M1/M2 Macrophages in Diabetic Nephropathy: Nrf2/HO-1 as Therapeutic Targets. 61
30014796 2018
24
The Limitations of Gram-stain Microscopy of Synovial Fluid in Concomitant Septic and Crystal Arthritis. 61
28356052 2018
25
Shoulder Lesion in a 69 Year Old Woman. 61
29772993 2018
26
Direct crystal formation from micronized bone and lactic acid: The writing on the wall for calcium-containing crystal pathogenesis in osteoarthritis? 61
30388106 2018
27
The value of musculoskeletal ultrasound in geriatric care and rehabilitation. 61
28692451 2017
28
Arthropathy in Dermatology: A Comprehensive Review. 61
28405546 2017
29
Recent advances in understanding and managing gout. 61
28357052 2017
30
Is it easy to clinically distinguish inflammatory arthritis of bacterial origin from monoarthritis attacks of gout disease? 61
27902172 2016
31
Increasing Public Health Burden of Arthritis and Other Rheumatic Conditions and Comorbidity: Results From a Statewide Health Surveillance System, 2007-2012. 61
26866827 2016
32
Klebsiella pyomyositis with complications: a quadriceps quandary in a dialysis patient. 61
29497541 2016
33
Wide-field imaging of birefringent synovial fluid crystals using lens-free polarized microscopy for gout diagnosis. 61
27356625 2016
34
Synovial Fluid Findings and Demographic Analysis of Patients With Coexistent Intra-articular Monosodium Urate and Calcium Pyrophosphate Crystals. 61
26906297 2016
35
Native Joint Septic Arthritis: Epidemiology, Clinical Features, and Microbiological Causes in a New Zealand Population. 61
26523022 2015
36
[Indications and contraindications for radiosynoviorthesis]. 61
26555659 2015
37
Hospital burden of gout, pseudogout and other crystal arthropathies in France. 61
25881756 2015
38
[Austrian nutrition and lifestyle recommendations for gout and hyperuricemia]. 61
26014619 2015
39
Hypophosphatasia: validation and expansion of the clinical nosology for children from 25 years experience with 173 pediatric patients. 61
25731960 2015
40
[Gout and and calcium pyrophosphate crystal arthropathies: pathophysiology]. 61
26165104 2015
41
Prevalence of musculoskeletal disorders and rheumatic diseases in an urban community in Monagas State, Venezuela: a COPCORD study. 61
24924602 2015
42
Detection and characterization of crystal suspensions using single-source dual-energy computed tomography: a phantom model of crystal arthropathies. 61
25333310 2015
43
Use of ultrasound for diagnosis and monitoring of outcomes in crystal arthropathies. 61
25633243 2015
44
Persistent spontaneous synovial drainage from digital flexor sheath in proliferative tenosynovitis: Two case reports and a review of the literature. 61
26090353 2015
45
Unlocking the jaw: advanced imaging of the temporomandibular joint. 61
25341144 2014
46
Tophaceous calcium pyrophosphate dihydrate deposition disease of the knee mimicking an aggressive soft tissue tumour. 61
24916978 2014
47
Crystal arthropathies: The NET is closing in on inflammation in gout. 61
24818672 2014
48
Gout and crystal arthropathies. 61
24703354 2014
49
Gout and crystal arthropathies. 61
24703355 2014
50
[Chondrocalcinosis due to calcium pyrophosphate deposition (CPPD). From incidental radiographic findings to CPPD crystal arthritis]. 61
24811359 2014

Variations for Crystal Arthropathies

Expression for Crystal Arthropathies

Search GEO for disease gene expression data for Crystal Arthropathies.

Pathways for Crystal Arthropathies

GO Terms for Crystal Arthropathies

Sources for Crystal Arthropathies

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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