MCID: CTN009
MIFTS: 28

Cutaneous Adenocystic Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Cutaneous Adenocystic Carcinoma

MalaCards integrated aliases for Cutaneous Adenocystic Carcinoma:

Name: Cutaneous Adenocystic Carcinoma 12 15
Adenoid Cystic Eccrine Carcinoma 12 71
Adenoid Cystic Eccrine Carcinoma of Skin 12
Adenoid Cystic Carcinoma of the Skin 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4871
NCIt 49 C4471
UMLS 71 C0346017

Summaries for Cutaneous Adenocystic Carcinoma

MalaCards based summary : Cutaneous Adenocystic Carcinoma, also known as adenoid cystic eccrine carcinoma, is related to adenoid basal cell carcinoma and basal cell carcinoma, and has symptoms including pain An important gene associated with Cutaneous Adenocystic Carcinoma is MYBL1 (MYB Proto-Oncogene Like 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Keratinization. Affiliated tissues include breast, skin and colon, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Cutaneous Adenocystic Carcinoma

Diseases related to Cutaneous Adenocystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 386)
# Related Disease Score Top Affiliating Genes
1 adenoid basal cell carcinoma 29.7 LALBA KRT7 KIT ACCS
2 basal cell carcinoma 28.7 MME KRT8 KRT7 KRT5 KRT19 KIT
3 adenoid cystic carcinoma 28.2 PGR NFIB MYBL1 KRT7 KRT5 KRT19
4 neurenteric cyst 10.5 KRT8 KRT18
5 classic pulmonary blastoma 10.5 NKX2-1 CEACAM5
6 urethral villous adenoma 10.5 KRT7 CEACAM5
7 cutaneous mucoepidermoid carcinoma 10.5 KRT7 CEACAM5
8 seminal vesicle adenocarcinoma 10.5 KRT7 CEACAM5
9 pancreatic foamy gland adenocarcinoma 10.5 KRT7 CEACAM5
10 endolymphatic sac tumor 10.5 KRT8 KRT7
11 mucinous adenofibroma 10.5 KRT7 CEACAM5
12 aortic malignant tumor 10.5 KRT7 CEACAM5
13 urinary bladder villous adenoma 10.5 KRT7 CEACAM5
14 sigmoid neoplasm 10.5 KRT7 CEACAM5
15 mucinous intrahepatic cholangiocarcinoma 10.5 KRT7 CEACAM5
16 bile duct cystadenocarcinoma 10.5 KRT7 CEACAM5
17 colonic lymphangioma 10.5 KRT7 CEACAM5
18 jejunal adenocarcinoma 10.5 KRT7 CEACAM5
19 krukenberg carcinoma 10.5 KRT7 CEACAM5
20 vaginal tubulovillous adenoma 10.5 KRT7 CEACAM5
21 vaginal adenoma 10.5 KRT7 CEACAM5
22 mucinous ovarian cystadenoma 10.5 KRT7 CEACAM5
23 small cell carcinoma of the bladder 10.5 NKX2-1 KRT7
24 transverse colon cancer 10.5 KRT7 CEACAM5
25 appendiceal neoplasm 10.5 KRT7 CEACAM5
26 rete testis neoplasm 10.5 NKX2-1 KRT7
27 cryptogenic cirrhosis 10.5 KRT8 KRT18
28 liver lymphoma 10.5 MME CEACAM5
29 rete testis adenocarcinoma 10.5 NKX2-1 KRT7
30 biliary papillomatosis 10.5 KRT7 CEACAM5
31 appendix adenocarcinoma 10.4 KRT7 CEACAM5
32 ectopic thymus 10.4 NKX2-1 KRT8
33 solid adenocarcinoma with mucin production 10.4 NKX2-1 KRT7
34 idiopathic corneal edema 10.4 KRT8 KRT19
35 nephrogenic adenoma of urinary bladder 10.4 MME KRT7
36 wolffian duct adenoma 10.4 MME KRT7
37 liver sarcoma 10.4 KRT7 CEACAM5
38 synovium neoplasm 10.4 KRT8 KRT7
39 intrahepatic bile duct adenoma 10.4 KRT7 KRT19
40 bile duct adenoma 10.4 KRT7 KRT19
41 malignant struma ovarii 10.4 NKX2-1 KRT19
42 struma ovarii 10.4 NKX2-1 KRT19
43 mixed epithelial stromal tumour 10.4 MME KRT7
44 cervical adenoma malignum 10.4 MME KRT7
45 ovarian mucinous neoplasm 10.4 KRT7 CEACAM5
46 epididymal neoplasm 10.4 MME KRT7
47 ovarian wilms' cancer 10.4 MME KRT7
48 clear cell papillary renal cell carcinoma 10.4 MME KRT7
49 chromophil adenoma of the kidney 10.4 MME KRT7
50 tall cell variant papillary carcinoma 10.4 NKX2-1 KRT19

Graphical network of the top 20 diseases related to Cutaneous Adenocystic Carcinoma:



Diseases related to Cutaneous Adenocystic Carcinoma

Symptoms & Phenotypes for Cutaneous Adenocystic Carcinoma

UMLS symptoms related to Cutaneous Adenocystic Carcinoma:


pain

GenomeRNAi Phenotypes related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.5 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.5 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.5 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.5 KRT18
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.5 KRT8
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.5 KRT7
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.5 KRT18 KRT5 KRT7 KRT8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-72 9.5 KRT7
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.5 KRT18
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.5 KRT5 KRT7

MGI Mouse Phenotypes related to Cutaneous Adenocystic Carcinoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.86 B2M KIT KRT19 KRT5 KRT8 NFIB
2 endocrine/exocrine gland MP:0005379 9.81 B2M KIT KRT19 LALBA MYBL1 NFIB
3 integument MP:0010771 9.56 B2M KIT KRT19 KRT5 LALBA MME
4 reproductive system MP:0005389 9.23 B2M KIT KRT19 KRT8 MYBL1 NKX2-1

Drugs & Therapeutics for Cutaneous Adenocystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Cutaneous Adenocystic Carcinoma

Genetic Tests for Cutaneous Adenocystic Carcinoma

Anatomical Context for Cutaneous Adenocystic Carcinoma

MalaCards organs/tissues related to Cutaneous Adenocystic Carcinoma:

40
Breast, Skin, Colon, Lung, Thymus, Liver, Kidney

Publications for Cutaneous Adenocystic Carcinoma

Articles related to Cutaneous Adenocystic Carcinoma:

# Title Authors PMID Year
1
Immunohistochemical demonstration of myoepithelial cells in sweat gland carcinomas. 61
8186107 1994

Variations for Cutaneous Adenocystic Carcinoma

Expression for Cutaneous Adenocystic Carcinoma

Search GEO for disease gene expression data for Cutaneous Adenocystic Carcinoma.

Pathways for Cutaneous Adenocystic Carcinoma

Pathways related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.04 KRT8 KRT7 KRT5 KRT19 KRT18
2
Show member pathways
11.81 KRT8 KRT7 KRT5 KRT19 KRT18
3 11.5 MME KIT CEACAM5
4
Show member pathways
11.05 KRT8 KRT7 KRT5 KRT19 KRT18

GO Terms for Cutaneous Adenocystic Carcinoma

Cellular components related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.81 PIP MME KRT8 KRT7 KRT5 KRT19
2 cell periphery GO:0071944 9.43 KRT8 KRT19 KRT18
3 apicolateral plasma membrane GO:0016327 9.4 KRT8 KRT19
4 costamere GO:0043034 9.37 KRT8 KRT19
5 dystrophin-associated glycoprotein complex GO:0016010 9.32 KRT8 KRT19
6 keratin filament GO:0045095 9.26 KRT8 KRT7 KRT5 KRT18
7 intermediate filament GO:0005882 9.02 KRT8 KRT7 KRT5 KRT19 KRT18

Biological processes related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lung development GO:0030324 9.58 NKX2-1 NFIB MME
2 hepatocyte apoptotic process GO:0097284 9.37 KRT8 KRT18
3 keratinization GO:0031424 9.35 KRT8 KRT7 KRT5 KRT19 KRT18
4 cell differentiation involved in embryonic placenta development GO:0060706 9.32 KRT8 KRT19
5 type II pneumocyte differentiation GO:0060510 9.26 NKX2-1 NFIB
6 Clara cell differentiation GO:0060486 9.16 NKX2-1 NFIB
7 cornification GO:0070268 9.02 KRT8 KRT7 KRT5 KRT19 KRT18

Molecular functions related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 scaffold protein binding GO:0097110 8.8 KRT8 KRT5 KRT18

Sources for Cutaneous Adenocystic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....