MCID: CTN009
MIFTS: 26

Cutaneous Adenocystic Carcinoma

Categories: Cancer diseases, Skin diseases

Aliases & Classifications for Cutaneous Adenocystic Carcinoma

MalaCards integrated aliases for Cutaneous Adenocystic Carcinoma:

Name: Cutaneous Adenocystic Carcinoma 12 15
Adenoid Cystic Eccrine Carcinoma 12 72
Adenoid Cystic Eccrine Carcinoma of Skin 12
Adenoid Cystic Carcinoma of the Skin 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4871
NCIt 50 C4471
UMLS 72 C0346017

Summaries for Cutaneous Adenocystic Carcinoma

MalaCards based summary : Cutaneous Adenocystic Carcinoma, also known as adenoid cystic eccrine carcinoma, is related to adenoid cystic carcinoma and basal cell carcinoma, and has symptoms including pain An important gene associated with Cutaneous Adenocystic Carcinoma is KRT8 (Keratin 8), and among its related pathways/superpathways are Cytoskeletal Signaling and Keratinization. Affiliated tissues include skin, and related phenotypes are digestive/alimentary and endocrine/exocrine gland

Related Diseases for Cutaneous Adenocystic Carcinoma

Diseases related to Cutaneous Adenocystic Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 30.0 NFIB MYBL1 KRT7 KRT19
2 basal cell carcinoma 29.9 KRT8 KRT7 KRT19
3 adenoid basal cell carcinoma 29.3 LALBA KRT7 CEACAM5 B2M
4 neurenteric cyst 10.7 KRT8 KRT18
5 endolymphatic sac tumor 10.6 KRT8 KRT7
6 hidrocystoma 10.6 KRT8 KRT7
7 adenoid squamous cell carcinoma 10.6 KRT8 KRT7
8 cryptogenic cirrhosis 10.6 KRT8 KRT18
9 apocrine sweat gland neoplasm 10.6 KRT8 KRT7
10 nasal cavity cancer 10.6 KRT8 KRT7
11 epithelioid trophoblastic tumor 10.6 KRT7 KRT18
12 brooke-spiegler syndrome 10.6 KRT8 KRT7
13 metanephric adenoma 10.6 KRT7 KRT18
14 papillary ependymoma 10.6 KRT8 KRT18
15 seminal vesicle tumor 10.6 KRT7 KRT18
16 pleomorphic carcinoma 10.5 KRT8 KRT7
17 nasal cavity squamous cell carcinoma 10.5 KRT8 KRT7
18 atypical choroid plexus papilloma 10.5 KRT8 KRT7
19 basaloid squamous cell carcinoma 10.5 KRT8 KRT7
20 gastric tubular adenocarcinoma 10.4 KRT8 KRT7
21 mammary paget's disease 10.4 KRT8 KRT7
22 breast adenoid cystic carcinoma 10.4 NFIB MYBL1
23 ceruminoma 10.4 PIP KRT7
24 ovarian cystic teratoma 10.4 KRT7 B2M
25 oncocytic breast carcinoma 10.4 PIP KRT7
26 large intestine adenocarcinoma 10.4 PIP KRT7
27 lymphoepithelioma-like carcinoma 10.4 KRT8 KRT7 KRT18
28 nephrogenic adenofibroma 10.4 KRT8 KRT7 KRT18
29 microglandular adenosis 10.4 PIP KRT18
30 sweat gland cancer 10.4 KRT8 KRT7 KRT18
31 chromophobe renal cell carcinoma 10.4 KRT8 KRT7 KRT18
32 oncocytoma 10.4 KRT8 KRT7 KRT18
33 cecum adenocarcinoma 10.3 KRT7 B2M
34 transitional cell carcinoma 10.3 KRT8 KRT7 KRT18
35 epithelioid sarcoma 10.3 KRT8 KRT7
36 paget disease, extramammary 10.3 PIP KRT7
37 cutaneous mucoepidermoid carcinoma 10.3 KRT7 CEACAM5
38 malignant spiradenoma 10.3 KRT7 CEACAM5
39 mucinous adenofibroma 10.3 KRT7 CEACAM5
40 bile duct mucoepidermoid carcinoma 10.3 KRT7 CEACAM5
41 ovarian brenner tumor 10.3 KRT7 KRT18
42 ovarian lymphoma 10.3 KRT18 CEACAM5
43 bile duct cystadenocarcinoma 10.3 KRT7 CEACAM5
44 meibomian cyst 10.3 KRT7 CEACAM5
45 thymus adenocarcinoma 10.3 KRT7 CEACAM5
46 pancreatic serous cystadenoma 10.3 KRT7 CEACAM5
47 malignant biphasic mesothelioma 10.3 KRT7 CEACAM5
48 hidradenocarcinoma 10.2 PIP KRT7
49 rectum adenocarcinoma 10.2 KRT7 CEACAM5
50 mucinous ovarian cystadenoma 10.2 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Cutaneous Adenocystic Carcinoma:



Diseases related to Cutaneous Adenocystic Carcinoma

Symptoms & Phenotypes for Cutaneous Adenocystic Carcinoma

UMLS symptoms related to Cutaneous Adenocystic Carcinoma:


pain

MGI Mouse Phenotypes related to Cutaneous Adenocystic Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.35 B2M KRT19 KRT8 NFIB PIP
2 endocrine/exocrine gland MP:0005379 9.1 B2M KRT19 LALBA MYBL1 NFIB PIP

Drugs & Therapeutics for Cutaneous Adenocystic Carcinoma

Search Clinical Trials , NIH Clinical Center for Cutaneous Adenocystic Carcinoma

Genetic Tests for Cutaneous Adenocystic Carcinoma

Anatomical Context for Cutaneous Adenocystic Carcinoma

MalaCards organs/tissues related to Cutaneous Adenocystic Carcinoma:

41
Skin

Publications for Cutaneous Adenocystic Carcinoma

Articles related to Cutaneous Adenocystic Carcinoma:

# Title Authors PMID Year
1
Immunohistochemical demonstration of myoepithelial cells in sweat gland carcinomas. 38
8186107 1994

Variations for Cutaneous Adenocystic Carcinoma

Expression for Cutaneous Adenocystic Carcinoma

Search GEO for disease gene expression data for Cutaneous Adenocystic Carcinoma.

Pathways for Cutaneous Adenocystic Carcinoma

Pathways related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.95 KRT8 KRT7 KRT19 KRT18
2
Show member pathways
11.71 KRT8 KRT7 KRT19 KRT18
3
Show member pathways
10.96 KRT8 KRT7 KRT19 KRT18
4 10.8 KRT8 KRT19

GO Terms for Cutaneous Adenocystic Carcinoma

Cellular components related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.7 PIP KRT8 KRT7 KRT19 KRT18 CEACAM5
2 keratin filament GO:0045095 9.43 KRT8 KRT7 KRT18
3 dystrophin-associated glycoprotein complex GO:0016010 9.4 KRT8 KRT19
4 costamere GO:0043034 9.37 KRT8 KRT19
5 apicolateral plasma membrane GO:0016327 9.32 KRT8 KRT19
6 cell periphery GO:0071944 9.13 KRT8 KRT19 KRT18
7 intermediate filament GO:0005882 8.92 KRT8 KRT7 KRT19 KRT18

Biological processes related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.62 KRT8 KRT7 KRT19 KRT18
2 extrinsic apoptotic signaling pathway GO:0097191 9.43 KRT8 KRT18
3 retina homeostasis GO:0001895 9.4 PIP B2M
4 sarcomere organization GO:0045214 9.37 KRT8 KRT19
5 hepatocyte apoptotic process GO:0097284 9.26 KRT8 KRT18
6 keratinization GO:0031424 9.26 KRT8 KRT7 KRT19 KRT18
7 cell differentiation involved in embryonic placenta development GO:0060706 9.16 KRT8 KRT19
8 cornification GO:0070268 8.92 KRT8 KRT7 KRT19 KRT18

Molecular functions related to Cutaneous Adenocystic Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 8.32 KRT18

Sources for Cutaneous Adenocystic Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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