MCID: CTN013
MIFTS: 36

Cutaneous Anthrax

Categories: Infectious diseases, Rare diseases, Respiratory diseases, Skin diseases

Aliases & Classifications for Cutaneous Anthrax

MalaCards integrated aliases for Cutaneous Anthrax:

Name: Cutaneous Anthrax 12 77 54 45 15 74
Anthrax, Skin Type 54
Skin Anthrax 54

Classifications:



External Ids:

Disease Ontology 12 DOID:7426
ICD9CM 36 022.0
MeSH 45 C531621
SNOMED-CT 69 84980006
ICD10 34 A22.0
UMLS 74 C0003177

Summaries for Cutaneous Anthrax

Disease Ontology : 12 An anthrax disease that results in infection located in skin, has material basis in Bacillus anthracis, which is transmitted by contact with infected animals or animal products. The infection has symptom skin lesion that eventually forms an ulcer with a black center.

MalaCards based summary : Cutaneous Anthrax, also known as anthrax, skin type, is related to anthrax disease and 3-methylglutaconic aciduria, type iii, and has symptoms including skin lesion An important gene associated with Cutaneous Anthrax is PON1 (Paraoxonase 1), and among its related pathways/superpathways is Legionellosis. Affiliated tissues include skin, lung and t cells, and related phenotypes are Decreased NANOG protein expression and Decreased NANOG protein expression

Wikipedia : 77 Anthrax is an infection caused by the bacterium Bacillus anthracis. It can occur in four forms: skin,... more...

Related Diseases for Cutaneous Anthrax

Diseases related to Cutaneous Anthrax via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 anthrax disease 33.1 CASP1 PRDX1
2 3-methylglutaconic aciduria, type iii 9.9
3 diabetes mellitus 9.9
4 hemolytic anemia 9.9
5 erythema multiforme 9.9
6 ulnar nerve lesion 9.9
7 cicatricial ectropion 9.9
8 urticaria 9.9
9 ectropion 9.9
10 cellulitis 9.9
11 hypokalemia 9.9
12 behcet syndrome 9.8 ADA HSPD1 PON1

Graphical network of the top 20 diseases related to Cutaneous Anthrax:



Diseases related to Cutaneous Anthrax

Symptoms & Phenotypes for Cutaneous Anthrax

Symptoms:

12
  • skin lesion

GenomeRNAi Phenotypes related to Cutaneous Anthrax according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased NANOG protein expression GR00184-A-3 10.06 ADA IBSP LARS
2 Decreased NANOG protein expression GR00184-A-6 10.06 IBSP LARS
3 Decreased NANOG protein expression GR00184-A-8 10.06 ADA IBSP LARS
4 Decreased OCT4 protein expression GR00184-A-2 9.86 ADA IBSP LARS
5 Decreased OCT4 protein expression GR00184-A-5 9.86 ADA IBSP LARS
6 Decreased OCT4 protein expression GR00184-A-7 9.86 IBSP LARS
7 Decreased POU5F1-GFP protein expression GR00184-A-1 9.1 ADA IBSP LARS
8 Decreased POU5F1-GFP protein expression GR00184-A-4 9.1 ADA IBSP LARS

Drugs & Therapeutics for Cutaneous Anthrax

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Natural History of Anthrax: a Study of Primary Infected, Recovered, and Exposed Individuals (SPoRE); and Evaluation of AVA-Vaccinated Recipients Recruiting NCT00050310

Search NIH Clinical Center for Cutaneous Anthrax

Cochrane evidence based reviews: cutaneous anthrax

Genetic Tests for Cutaneous Anthrax

Anatomical Context for Cutaneous Anthrax

MalaCards organs/tissues related to Cutaneous Anthrax:

42
Skin, Lung, T Cells, Brain, Liver, Testes, Lymph Node

The Foundational Model of Anatomy Ontology organs/tissues related to Cutaneous Anthrax:

20
Skin

Publications for Cutaneous Anthrax

Articles related to Cutaneous Anthrax:

(show top 50) (show all 172)
# Title Authors Year
1
An ELISA using a recombinant chimera of protective antigen and lethal factor for serodiagnosis of cutaneous anthrax in India. ( 30635155 )
2019
2
Cutaneous Anthrax Outbreak in the Trakya Region of Turkey ( 30701847 )
2019
3
Rates and risk factors for human cutaneous anthrax in the country of Georgia: National surveillance data, 2008-2015. ( 29415029 )
2018
4
Correction: Rates and risk factors for human cutaneous anthrax in the country of Georgia: National surveillance data, 2008-2015. ( 29718987 )
2018
5
Two cases of human cutaneous anthrax with massive tissue damage, severe edema, and slight injury to the liver. ( 29231245 )
2018
6
Risk factors for human cutaneous anthrax outbreaks in the hotspot districts of Northern Tanzania: an unmatched case-control study. ( 30839712 )
2018
7
Immune-modulating Activity of Hydrogel Microparticles Contributes to the Host Defense in a Murine Model of Cutaneous Anthrax. ( 28894739 )
2017
8
Diagnosis of cutaneous anthrax in resource-poor settings in West Arsi Province, Ethiopia. ( 29284252 )
2017
9
Evaluation of Clinical and Serological Findings For Diagnosis of Cutaneous Anthrax Infection after an Outbreak. ( 28076993 )
2017
10
Cutaneous Anthrax. ( 27742398 )
2016
11
Evaluation of cutaneous anthrax cases during an outbreak in the east region of Turkey. ( 27966316 )
2016
12
Source and risk factors of a cutaneous anthrax outbreak, Jiangsu, Eastern China, 2012. ( 27277672 )
2016
13
Cutaneous Anthrax on Eyelid in a Pregnant Woman. ( 27551179 )
2016
14
Serum paraoxonase activity and oxidative stress levels in patients with cutaneous anthrax. ( 27461010 )
2016
15
An outbreak of cutaneous anthrax in Yunnan, China. ( 27329849 )
2016
16
Human Cutaneous Anthrax, the East Anatolian Region of Turkey 2008-2014. ( 26720232 )
2016
17
Spatiotemporal Clustering Analysis and Risk Assessments of Human Cutaneous Anthrax in China, 2005-2012. ( 26208355 )
2015
18
A case of cutaneous anthrax presenting with classical lesions. ( 26340973 )
2015
19
Cutaneous anthrax: evaluation of 28 cases in the Eastern Anatolian region of Turkey. ( 26225872 )
2015
20
Two cases of human cutaneous anthrax in Bosnia and Herzegovina, September 2014. ( 25719961 )
2015
21
Genome Sequence of Bacillus anthracis Larissa, Associated with a Case of Cutaneous Anthrax in Greece. ( 26564034 )
2015
22
Periorbital cellulitis due to cutaneous anthrax. ( 25763844 )
2015
23
Cutaneous anthrax in an unusual location: case report. ( 26700091 )
2015
24
Development & validation of a quantitative anti-protective antigen IgG enzyme linked immunosorbent assay for serodiagnosis of cutaneous anthrax. ( 26354217 )
2015
25
Natural cutaneous anthrax infection, but not vaccination, induces a CD4(+) T cell response involving diverse cytokines. ( 26075052 )
2015
26
Cutaneous anthrax: evaluation of 28 cases in the Eastern Anatolian region of Turkey. ( 26293781 )
2015
27
Human cutaneous anthrax, Georgia 2010-2012. ( 24447721 )
2014
28
Retrospective review of the case of cutaneous anthrax-malignant pustule from 1995 in 15-year old girl. ( 25848786 )
2014
29
Whole proteome analysis of mouse lymph nodes in cutaneous anthrax. ( 25329596 )
2014
30
Exoproteome analysis of a novel strain of Bacillus cereus implicated in disease resembling cutaneous anthrax. ( 24412723 )
2014
31
Cutaneous anthrax in a school teacher. ( 24858169 )
2014
32
Three eyelid localized cutaneous anthrax cases. ( 24641116 )
2014
33
Serum adenosine deaminase activity in cutaneous anthrax. ( 24997584 )
2014
34
Optic Atrophy Secondary to Preseptal Cutaneous Anthrax: Case Report. ( 27928303 )
2014
35
Cutaneous anthrax in Southeast Anatolia of Turkey. ( 24678748 )
2014
36
Asymmetric dimethylarginine levels in patients with cutaneous anthrax: a laboratory analysis. ( 24669818 )
2014
37
Serodiagnosis of human cutaneous anthrax in India using an indirect anti-lethal factor IgG enzyme-linked immunosorbent assay. ( 23269414 )
2013
38
Cutaneous anthrax resulting in renal failure with generalized tissue damage. ( 23431997 )
2013
39
Suspect vector transmission of human cutaneous anthrax during an animal outbreak in Southern Italy. ( 23808978 )
2013
40
Periocular cutaneous anthrax in Jimma Zone, Southwest Ethiopia: a case series. ( 23924443 )
2013
41
Field-based PCR for rapid diagnosis of cutaneous anthrax in the deployed setting using the joint biological agent identification and diagnostic system. ( 23929060 )
2013
42
Fatal cutaneous anthrax in a heroin user. ( 23374534 )
2013
43
Three probable cases of cutaneous anthrax in autonomous province of Vojvodina, Serbia, June 2011. ( 22264812 )
2012
44
Outbreak of cutaneous anthrax in a tribal village: a clinico-epidemiological study. ( 22715553 )
2012
45
Naturally occurring cutaneous anthrax: antibiotic treatment and outcome. ( 22343361 )
2012
46
Anti-protective antigen IgG enzyme-linked immunosorbent assay for diagnosis of cutaneous anthrax in India. ( 22718130 )
2012
47
Outbreak of cutaneous anthrax in Musalimadugu village, Chittoor district, Andhra Pradesh, India, July-August 2011. ( 23103890 )
2012
48
Increased membrane turnover in the brain in cutaneous anthrax without central nervous system disorder: a magnetic resonance spectroscopy study. ( 22543072 )
2012
49
Recent outbreak of cutaneous anthrax in Bangladesh: clinico-demographic profile and treatment outcome of cases attended at Rajshahi Medical College Hospital. ( 22929128 )
2012
50
Investigation of an outbreak of cutaneous anthrax in Banlu village, Lianyungang, China, 2012. ( 23908932 )
2012

Variations for Cutaneous Anthrax

Expression for Cutaneous Anthrax

Search GEO for disease gene expression data for Cutaneous Anthrax.

Pathways for Cutaneous Anthrax

Pathways related to Cutaneous Anthrax according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.54 CASP1 EEF1A1 HSPD1

GO Terms for Cutaneous Anthrax

Cellular components related to Cutaneous Anthrax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.4 ACOT13 ADA CASP1 CEP70 EEF1A1 HSPD1
2 myelin sheath GO:0043209 8.96 DLD PRDX1

Biological processes related to Cutaneous Anthrax according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of T cell activation GO:0050870 8.62 ADA HSPD1

Sources for Cutaneous Anthrax

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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